Hub : Genes

Ncaph2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000055808 0.02 0.02 3.4e-03 0 0.01 0 0 1.6e-01 1.0e-02 2.0e-01 8.3e-02
2 Adipose alternative polyA ENSRNOT00000084776 0.02 0.02 5.2e-03 0 0.01 -0 0 2.2e-01 2.3e-02 4.3e-01 1.6e-01
3 Brain alternative polyA ENSRNOT00000055808 0.03 0.03 4.4e-03 0.03 0.02 0.01 0.02 8.1e-04 1.0e-02 5.4e-02 9.0e-03
4 Brain alternative polyA ENSRNOT00000084776 0.03 0.03 4.2e-03 0.03 0.02 0.01 0.02 6.3e-04 1.0e-02 5.8e-02 9.8e-03
5 Brain gene expression ENSRNOG00000009598 0.04 0.03 6.1e-05 0.04 0.05 0.04 0.04 1.7e-04 3.6e-05 8.6e-05 2.7e-04
6 IL gene expression ENSRNOG00000009598 0.22 0.11 1.3e-04 0.19 0.12 0.17 0.16 2.4e-05 7.0e-04 8.0e-05 1.4e-04
7 Liver gene expression ENSRNOG00000009598 0.12 0.05 2.2e-15 0.1 0.09 0.09 0.09 4.5e-11 2.3e-10 2.1e-10 1.3e-10
8 NAcc gene expression ENSRNOG00000009598 0.04 0.03 4.2e-03 0.03 0.02 0.01 0.02 5.3e-03 1.9e-02 4.7e-02 1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail4.514.516.63.9-3.83.5-3.5-3.5-4.04.0-4.1
BMI without tail2.96.18.32.5-2.52.1-2.1-2.3-2.42.9-2.9
Body weight2.29.310.03.2-3.12.9-2.9-2.9-3.13.2-3.1
Epididymis fat weight0.92.03.31.8-1.60.3-0.3-1.1-1.81.7-1.6
Glucose0.50.71.0-0.90.9-0.30.30.91.0-0.91.0
Heart weight0.20.30.7-0.50.5-0.80.80.30.4-0.50.4
Left kidney weight4.412.715.53.8-3.82.8-2.8-3.6-3.63.9-3.9
Right kidney weight8.022.926.25.1-5.04.2-4.2-4.8-4.75.1-5.1
Tail length0.41.21.8-1.11.1-1.01.01.01.3-1.01.1
Length with tail0.00.10.3-0.20.3-0.20.20.30.4-0.50.6
Length without tail0.40.81.21.1-1.00.9-0.9-0.9-1.10.7-0.7
Liver weight, left0.10.10.3-0.30.40.3-0.30.40.2-0.50.5
Liver weight, right1.01.72.4-1.21.3-1.11.11.51.2-1.51.5
Parametrial fat weight0.20.30.80.3-0.40.9-0.9-0.6-0.30.3-0.4
Retroperitoneal fat weight1.13.64.61.9-1.91.8-1.8-1.7-1.82.1-2.1
Intraocular pressure0.20.30.7-0.40.4-0.80.80.7-0.4-0.10.0
Extensor digitorum longus weight0.31.41.61.1-1.11.2-1.2-1.1-1.21.2-1.3
Soleus weight1.02.93.11.7-1.71.8-1.8-1.7-1.61.7-1.7
Tibialis anterior weight0.00.00.10.2-0.2-0.00.0-0.1-0.20.2-0.3
Tibia length1.23.36.1-1.91.9-0.80.81.61.9-2.52.4
Number of licking bursts0.00.10.2-0.10.1-0.40.40.10.1-0.0-0.1
Food consumed during 24 hour testing period2.53.03.51.9-1.91.4-1.4-1.8-1.91.8-1.8
Times rat made contact with spout1.92.23.81.2-1.41.9-1.9-1.8-1.21.0-1.1
Mean time between licks in bursts2.53.44.3-2.12.0-1.91.91.81.8-1.71.6
Mean num. licks in bursts0.60.71.90.6-0.61.4-1.4-0.8-0.40.2-0.2
Std. dev. time between licks in bursts1.21.43.10.9-0.91.8-1.8-0.9-0.51.0-1.0
Water consumed over 24 hours0.91.02.20.9-0.91.5-1.5-1.0-0.60.6-0.7
Indifference point 0 sec0.30.50.70.8-0.80.5-0.5-0.7-0.80.7-0.8
Indifference point AUC0.60.71.4-0.81.0-0.50.51.20.9-0.80.7
Indifference point function ln k3.04.35.22.1-2.12.3-2.3-2.2-2.01.8-1.6
Indifference point function log k3.04.35.22.1-2.12.3-2.3-2.2-2.01.8-1.6
Delay discounting total patch changes 0 sec0.10.20.30.5-0.50.2-0.2-0.4-0.50.4-0.6
Delay discounting total patch changes 12 sec0.10.10.2-0.10.2-0.50.50.50.1-0.1-0.0
Delay discounting total patch changes 18 sec1.82.43.3-1.51.6-1.61.61.81.4-1.51.3
Delay discounting total patch changes 24 sec0.91.12.6-0.70.8-1.61.61.10.4-0.80.7
Delay discounting total patch changes 6 sec0.00.00.1-0.10.20.2-0.20.30.3-0.0-0.1
Delay discounting time to switch 0 sec0.50.81.7-0.70.7-1.31.30.70.7-0.60.6
Delay discounting water rate 0 sec1.42.24.01.3-1.42.0-2.0-1.5-1.21.0-1.0
Delay discounting water rate 12 sec2.84.26.12.1-2.02.5-2.5-2.1-2.01.6-1.4
Delay discounting water rate 18 sec5.16.78.32.6-2.72.9-2.9-2.8-2.52.1-2.1
Delay discounting water rate 24 sec2.12.94.91.6-1.62.2-2.2-1.8-1.21.4-1.4
Delay discounting water rate 6 sec1.32.03.81.3-1.32.0-2.0-1.4-0.91.0-0.9
Locomotor activity0.10.10.20.4-0.30.4-0.4-0.1-0.40.4-0.5
Locomotor testing distance0.50.80.9-1.00.9-0.80.80.90.9-0.90.8
Locomotor testing rearing0.40.61.2-0.70.8-0.40.41.10.8-0.80.8
Light reinforcement 10.20.40.80.8-0.70.2-0.2-0.5-0.60.7-0.9
Light reinforcement 22.02.73.41.8-1.71.6-1.6-1.5-1.41.6-1.8
Reaction time number correct0.50.81.2-1.01.0-0.20.20.91.0-1.01.1
Reaction time mean minus median0.00.00.10.2-0.1-0.20.2-0.0-0.30.3-0.3
Reaction time mean minus median AUC0.10.10.20.4-0.40.1-0.1-0.4-0.20.4-0.4
Reaction time num false alarms0.30.41.1-0.40.4-1.11.10.60.3-0.20.4
Reaction time num false alarms AUC0.10.20.5-0.30.3-0.70.70.30.2-0.10.2
Reaction time trials correct on left0.50.81.2-1.01.0-0.20.20.91.0-1.01.1
Reaction time trials on left0.60.81.2-1.11.0-0.30.30.91.0-1.01.1
Reaction time mean0.10.10.4-0.30.2-0.70.70.10.1-0.30.2
Reaction time mean AUC0.20.20.6-0.50.4-0.80.80.30.2-0.40.3
Median of all reaction times0.10.20.6-0.40.3-0.80.80.10.1-0.40.3
Reaction time omissions1.21.63.0-1.21.1-1.71.71.11.0-0.90.9
Reaction time false alarm rate0.10.20.60.1-0.1-0.70.70.1-0.20.3-0.2
Reaction time premature initiation rate2.02.63.51.9-1.71.4-1.4-1.2-1.81.8-1.7
Reaction time premature initiations0.71.01.31.0-0.91.1-1.1-0.6-1.00.9-0.8
Std. dev. reaction times0.00.00.20.1-0.2-0.10.1-0.2-0.50.2-0.2
Reaction time trials completed0.60.81.2-1.11.0-0.30.30.91.0-1.01.1
Reaction time trials AUC0.30.50.8-0.80.8-0.10.10.70.7-0.80.9
Social response proportion0.50.50.8-0.70.7-0.90.90.80.2-0.70.7
Social responses0.30.50.9-0.50.6-1.01.00.80.1-0.60.5
Social time0.40.50.90.6-0.70.7-0.7-0.9-0.90.5-0.6
Conditioned locomotion0.40.50.70.7-0.70.4-0.4-0.7-0.80.8-0.7
Cocaine response after cond. corrected1.51.72.21.4-1.41.0-1.0-1.3-1.41.4-1.5
Cocaine response after cond. not corrected3.84.25.22.1-2.11.7-1.7-2.0-2.12.2-2.3
Cocaine response before conditioning1.11.31.71.1-1.11.0-1.0-1.0-1.21.3-1.3
Saline control response0.91.11.61.1-1.01.0-1.0-0.8-1.01.3-1.2
Condit. Reinf. active minus inactive responses0.30.30.7-0.40.5-0.40.40.70.2-0.80.8
Condit. Reinf. active-inactive response ratio0.30.30.6-0.30.3-0.80.80.5-0.1-0.50.6
Condit. Reinf. active responses0.00.10.20.2-0.10.2-0.20.2-0.5-0.10.1
Condit. Reinf. inactive responses0.50.71.30.7-0.71.2-1.2-0.6-0.80.6-0.7
Condit. Reinf. lever presses0.60.81.31.0-1.00.7-0.7-0.7-1.20.9-0.9
Condit. Reinf. lever reinforcers received0.00.00.10.2-0.00.2-0.20.3-0.4-0.20.2
Pavlov. Cond. lever latency1.21.72.8-1.41.4-0.90.91.31.7-1.21.3
Pavlov. Cond. magazine entry latency0.30.41.10.7-0.70.2-0.2-0.6-1.10.6-0.6
Pavlov. Cond. change in total contacts0.10.10.30.3-0.20.2-0.2-0.0-0.6-0.10.1
Pavlov. Cond. index score0.91.11.81.1-1.11.0-1.0-1.0-1.30.9-1.0
Pavlov. Cond. latency score1.31.62.51.4-1.31.1-1.1-1.2-1.61.1-1.2
Pavlov. Cond. lever contacts1.11.52.21.4-1.30.9-0.9-1.2-1.51.2-1.3
Pavlov. Cond. magazine entry number0.40.51.1-0.70.7-0.50.50.61.1-0.60.7
Pavlov. Cond. intertrial magazine entries0.30.31.10.3-0.31.0-1.0-0.50.30.2-0.1
Pavlov. Cond. lever-magazine prob. diff.0.81.01.61.1-1.00.9-0.9-0.9-1.30.8-0.9
Pavlov. Cond. response bias0.40.51.00.8-0.80.3-0.3-0.7-1.00.7-0.8
Conditioned reinforcement - actives0.30.30.50.6-0.60.2-0.2-0.5-0.70.6-0.5
Conditioned reinforcement - inactives0.40.40.60.7-0.70.4-0.4-0.8-0.80.8-0.7
Conditioned locomotion3.33.94.52.1-2.01.9-1.9-2.0-2.12.1-1.9
Intermittent access intake day 1-15 change1.01.01.41.0-1.01.2-1.2-1.1-0.80.9-0.9
Intermittent access intake escalation1.41.31.71.2-1.21.3-1.3-1.2-1.01.1-1.0
Intermittent access intake escalation 22.82.73.41.9-1.71.7-1.7-1.6-1.51.6-1.5
Intermitt. access day 1 inactive lever presses1.61.82.91.3-1.21.7-1.7-1.1-1.21.2-1.2
Intermitt. access day 15 inactive lever presses5.35.96.52.4-2.42.5-2.5-2.6-2.32.3-2.4
Intermitt. access escalation Index0.80.81.7-0.70.7-1.31.30.70.6-0.70.6
Intermittent access day 1 total infusions0.00.00.10.2-0.3-0.00.0-0.3-0.30.3-0.2
Intermittent access day 15 total infusions0.30.40.50.6-0.70.6-0.6-0.7-0.60.6-0.5
Intermittent access terminal intake (last 3 days)2.83.03.61.9-1.81.7-1.7-1.8-1.71.7-1.6
Intermittent access total infusions0.30.30.40.7-0.70.4-0.4-0.7-0.60.6-0.5
Intermittent access day 1 locomotion0.10.10.10.2-0.30.1-0.1-0.3-0.30.3-0.2
Intermittent access day 15 total locomotion0.50.50.80.6-0.60.9-0.9-0.6-0.60.7-0.6
Intermittent access total locomotion0.80.91.10.9-1.01.1-1.1-1.1-0.91.0-0.8
Intermittent access standard deviation1.41.42.01.2-1.21.4-1.4-1.4-1.01.0-1.0
Cocaine induced anxiety3.84.45.22.3-2.31.6-1.6-2.3-2.22.2-2.2
Post-drug Anxiety3.33.64.42.1-2.11.5-1.5-2.0-1.91.9-2.1
Baseline Anxiety1.11.21.4-1.11.1-0.90.91.21.2-1.11.1
Lifetime Intake0.30.40.50.6-0.70.5-0.5-0.7-0.70.6-0.5
Incentive Sensitization - Responses0.20.20.40.6-0.50.4-0.4-0.4-0.50.6-0.5
Incentive Sensitization - Breakpoint0.20.20.30.5-0.40.3-0.3-0.3-0.50.6-0.5
Progressive ratio test 1 active lever presses0.40.40.80.6-0.70.2-0.2-0.9-0.70.6-0.5
Progressive ratio test 1 breakpoint0.50.51.00.7-0.80.3-0.3-1.0-0.80.7-0.6
Progressive ratio test 1 inactive lever presses0.30.30.50.6-0.60.1-0.1-0.7-0.60.6-0.5
Progressive ratio test 2 active lever presses0.40.50.50.7-0.70.6-0.6-0.7-0.70.7-0.6
Progressive ratio test 2 breakpoint0.30.30.40.6-0.60.4-0.4-0.6-0.60.7-0.5
Progressive ratio test 2 inactive lever presses0.50.50.60.7-0.70.8-0.8-0.7-0.60.8-0.8
Total sessions with >9 infusions0.40.50.70.6-0.60.7-0.7-0.7-0.80.7-0.6
Short access day 1 total inactive lever presses4.34.86.02.2-2.31.7-1.7-2.4-2.42.4-2.3
Short access day 10 total inactive lever presses9.510.411.63.4-3.33.3-3.3-3.1-3.13.1-3.2
Short access day 1 total infusions0.80.81.10.8-0.90.8-0.8-1.1-1.10.9-0.8
Short access day 10 total infusions1.21.31.61.2-1.21.0-1.0-1.3-1.21.2-1.1
Short access total infusions0.60.60.90.7-0.80.7-0.7-0.9-0.90.8-0.7
Short access day 1 locomotion0.91.01.30.9-1.01.0-1.0-1.1-1.01.0-0.9
Short access day 10 total locomotion4.24.65.02.1-2.12.2-2.2-2.2-2.22.2-2.1
Short access total locomotion1.31.31.61.1-1.21.1-1.1-1.2-1.21.2-1.1
Compulsive drug intake0.70.70.9-0.80.8-0.90.90.90.8-0.90.7
One hour access (0.3 mA shock)0.30.30.60.8-0.60.7-0.7-0.5-0.40.5-0.5
One hour access (shock baseline)0.91.11.31.1-1.11.1-1.1-1.0-0.91.0-0.8
Number of responses in last shaping day0.10.10.3-0.10.00.5-0.5-0.2-0.10.1-0.1
Context. condit. distance diff. score1.72.12.91.3-1.41.3-1.3-1.5-1.71.5-1.5
Locomotion velocity, session 10.10.10.20.1-0.10.2-0.2-0.1-0.40.5-0.5
Locomotion distance, session 12.33.03.9-2.01.9-1.21.21.91.8-1.71.8
Locomotion velocity, session 20.60.71.30.8-0.80.4-0.4-0.6-1.01.1-1.1
Locomotion distance, session 21.01.42.0-1.31.3-0.70.71.21.4-1.21.2
Locomotion velocity, session 30.40.40.70.6-0.70.5-0.5-0.9-0.50.7-0.7
Locomotion distance, session 30.20.20.6-0.30.3-0.80.80.30.0-0.10.1
Stereotopy head waving bouts, day 32.42.83.6-1.61.6-1.91.91.81.5-1.51.6
Stereotopy head waving duration, day 30.91.11.6-0.91.0-1.31.31.00.8-0.91.0
Locomotion velocity, session 70.60.71.80.9-0.9-0.20.2-0.8-1.30.8-0.7
Locomotion distance, session 70.20.30.80.5-0.50.5-0.5-0.5-0.90.4-0.4
Stereotopy head waving bouts, day 70.30.30.8-0.40.5-0.60.60.40.9-0.30.4
Stereotopy head waving duration, day 70.81.02.0-0.80.8-1.41.40.81.1-0.60.7
Locomotion velocity, session 81.21.42.41.3-1.3-0.10.1-1.1-1.41.5-1.5
Locomotion distance, session 80.60.91.30.8-0.81.1-1.1-0.8-0.91.0-1.0
Degree of sensitization distance1.51.51.91.3-1.21.4-1.4-1.2-1.21.1-1.1
Degree of sensitization stereotypy0.00.00.2-0.00.0-0.10.1-0.10.50.1-0.0
Condit. Reinf. active minus inactive responses0.91.01.91.0-1.0-0.20.2-0.5-1.41.3-1.3
Condit. Reinf. active-inactive response ratio0.30.30.60.2-0.1-0.80.80.1-0.50.6-0.6
Condit. Reinf. active responses1.51.83.01.5-1.40.3-0.3-1.0-1.71.7-1.7
Condit. Reinf. inactive responses1.21.41.61.3-1.21.0-1.0-1.0-1.31.2-1.3
Incentive salience index mean1.31.62.91.4-1.30.2-0.2-0.8-1.71.6-1.6
Condit. Reinf. lever presses1.21.62.41.5-1.40.7-0.7-1.0-1.51.5-1.6
Time in familiar zone, hab. session 10.50.50.70.6-0.70.8-0.8-0.8-0.50.7-0.7
Time in novel zone, hab. session 11.11.11.5-1.01.0-1.21.21.21.0-0.80.8
Total zone transitions, hab. session 12.23.24.5-2.02.0-0.70.71.82.0-2.12.1
Total locomotion distance, hab. session 10.30.40.7-0.50.50.8-0.80.30.8-0.50.5
Locomotion velocity, hab. session 10.30.50.8-0.60.60.7-0.70.50.9-0.70.7
Time in familiar zone, hab. session 21.71.82.71.4-1.50.6-0.6-1.4-1.71.5-1.5
Time in novel zone, hab. session 22.12.23.3-1.61.6-1.21.21.51.8-1.41.4
Total zone transitions, hab. session 20.20.20.70.1-0.20.8-0.8-0.4-0.30.2-0.2
Total locomotion distance, hab. session 21.21.53.11.0-1.01.7-1.7-1.1-0.81.1-1.1
Locomotion velocity, hab. session 21.11.53.30.9-1.01.8-1.8-1.1-0.81.0-1.0
Novel to familiar place preference ratio0.30.31.0-0.30.3-1.01.00.30.2-0.10.1
Novelty place preference0.20.20.6-0.10.1-0.80.80.00.00.1-0.1
Time in novel zone, NPP test0.20.20.6-0.20.1-0.80.80.00.10.1-0.1
Total zone transitions, NPP test0.50.81.2-1.11.0-0.10.10.81.1-1.01.1
Total locomotion distance, NPP test0.10.10.4-0.20.20.6-0.60.10.30.00.0
Locomotion velocity, NPP test0.10.10.5-0.00.00.7-0.7-0.00.20.1-0.1
Pavlov. Cond. lever latency0.60.81.3-1.00.9-0.40.40.71.2-1.11.2
Pavlov. Cond. magazine entry latency0.70.92.1-0.70.7-1.51.50.90.5-0.70.7
Pavlov. Cond. change in total contacts0.50.51.7-0.30.4-1.31.30.8-0.3-0.10.0
Pavlov. Cond. index score0.20.20.70.00.0-0.80.80.3-0.30.0-0.1
Pavlov. Cond. latency score0.10.20.40.3-0.2-0.60.60.0-0.50.2-0.3
Pavlov. Cond. lever contacts1.01.22.21.2-1.10.1-0.1-0.7-1.51.4-1.5
Pavlov. Cond. magazine entry number0.60.81.90.6-0.61.4-1.4-0.9-0.40.6-0.5
Pavlov. Cond. intertrial magazine entries1.11.31.71.1-1.11.0-1.0-0.9-1.31.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.10.1-0.90.90.4-0.2-0.1-0.0
Pavlov. Cond. response bias0.20.20.40.3-0.2-0.60.60.0-0.50.4-0.5
Bone: apparent density1.21.93.3-1.21.3-1.81.81.41.4-0.91.0
Bone surface0.91.62.1-1.11.2-1.41.41.41.4-0.90.9
Bone volume1.42.32.9-1.41.5-1.71.71.61.6-1.31.3
Bone: connectivity density0.91.43.1-0.91.0-1.81.81.11.1-0.40.6
Bone: cortical apparent density2.53.33.7-1.91.8-1.71.71.71.7-1.91.9
Bone: cortical area0.10.10.50.3-0.30.4-0.4-0.1-0.70.2-0.2
Bone: cortical porosity0.10.10.30.4-0.30.3-0.3-0.1-0.30.4-0.5
Bone: cortical porosity0.60.71.10.8-0.71.0-1.0-0.5-0.60.8-1.0
Bone: cortical thickness0.10.10.3-0.30.30.1-0.10.3-0.2-0.50.5
Bone: cortical thickness0.10.21.00.2-0.20.2-0.2-0.3-1.0-0.1-0.0
Bone: cortical tissue density2.33.03.4-1.81.8-1.61.61.61.7-1.81.8
Bone: elastic displacement0.10.20.8-0.40.4-0.10.10.30.9-0.20.1
Bone: elastic work0.30.41.00.5-0.51.0-1.0-0.6-0.20.5-0.6
Bone: endosteal estimation0.10.20.40.4-0.30.5-0.5-0.2-0.40.5-0.6
Bone: endosteal perimeter0.10.20.40.5-0.3-0.10.10.3-0.60.5-0.6
Bone: final force0.10.20.4-0.60.6-0.30.30.6-0.0-0.60.6
Bone: final moment0.20.30.6-0.70.7-0.30.30.60.2-0.70.7
Bone: marrow area0.00.10.20.3-0.20.3-0.3-0.1-0.30.3-0.5
Bone: maximum diameter0.50.92.01.0-1.00.6-0.6-0.6-1.41.0-1.1
Bone: maximum force0.00.10.1-0.30.30.3-0.30.20.0-0.30.4
Bone: maximum moment0.10.10.2-0.40.30.3-0.30.20.2-0.40.4
Bone: minimum diameter0.10.10.50.3-0.20.1-0.10.0-0.70.3-0.4
Bone: periosteal estimation0.10.20.50.5-0.40.6-0.6-0.2-0.70.4-0.5
Bone: periosteal perimeter0.20.30.80.7-0.50.3-0.3-0.1-0.90.6-0.7
Bone: post-yield work0.50.71.3-1.00.9-0.30.30.70.8-1.11.1
Bone: stiffness0.20.30.8-0.70.6-0.10.10.50.4-0.80.9
Bone: tissue strength0.60.61.8-0.80.70.6-0.60.31.3-0.60.7
Bone: trabecular number0.81.32.5-0.91.0-1.61.61.11.2-0.50.6
Bone: trabecular spacing2.22.94.41.6-1.62.1-2.1-1.7-1.71.3-1.4
Bone: trabecular thickness0.20.20.4-0.40.4-0.70.70.60.2-0.30.3
Bone: trabecular tissue density1.82.53.9-1.91.8-0.90.91.61.3-2.01.9
Breakpoint value in progressive ratio session1.21.41.81.2-1.11.3-1.3-1.1-1.01.0-1.1
Distance traveled before self-admin1.31.41.8-1.31.2-1.01.01.11.2-1.21.4
Distance traveled after self-admin0.10.10.20.2-0.3-0.10.1-0.3-0.40.4-0.1
Delta time in closed arm before/after self-admin0.20.20.30.3-0.30.5-0.5-0.4-0.40.3-0.4
Delta time in open arm before/after self-admin0.00.00.1-0.10.1-0.10.10.20.3-0.20.3
Diff in mean of infusions in LGA sessions1.61.82.61.5-1.50.9-0.9-1.3-1.51.5-1.6
Extinction: sum of active levers before priming0.10.10.2-0.00.10.5-0.50.10.2-0.2-0.3
Active lever presses in extinction session 62.42.32.41.5-1.51.5-1.5-1.5-1.51.5-1.3
Delta distance traveled before/after self-admin3.43.74.92.1-2.11.3-1.3-1.9-2.22.2-2.0
Delta ambulatory time before/after self-admin1.92.12.81.6-1.61.0-1.0-1.5-1.71.6-1.5
Time in closed arm before self-admin1.72.03.7-1.01.2-1.91.91.71.0-0.91.1
Time in closed arm after self-admin0.10.10.3-0.10.2-0.40.40.5-0.1-0.1-0.1
Time in open arm before self-admin0.10.10.30.1-0.30.3-0.3-0.6-0.20.1-0.5
Time in open arm after self-admin0.10.20.30.4-0.40.6-0.6-0.5-0.10.1-0.2
Sum of active levers in priming session hrs 5-60.20.20.30.4-0.40.1-0.1-0.3-0.50.6-0.5
Time to tail flick, vehicle, before self-admin1.11.11.41.1-1.01.1-1.1-0.9-1.01.1-1.2
Time to tail flick, vehicle, after self-admin0.80.81.31.1-1.00.4-0.4-0.8-1.11.1-0.9
Time to tail flick, test, before self-admin0.80.81.41.0-1.0-0.10.1-0.8-1.21.0-1.1
Time to tail flick, test, after self-admin1.92.02.71.5-1.51.0-1.0-1.4-1.61.6-1.5
Delta time to tail flick, vehicle, before/after SA0.80.81.2-0.80.8-1.11.10.90.8-0.90.9
Delta time to tail flick, test, before/after SA0.20.20.60.1-0.10.7-0.7-0.3-0.10.2-0.1
Ambulatory time before self-admin0.20.20.6-0.60.5-0.40.40.30.5-0.50.8
Ambulatory time after self-admin0.20.30.50.5-0.60.2-0.2-0.6-0.70.7-0.3
Total heroin consumption0.20.30.40.5-0.50.6-0.6-0.4-0.50.4-0.6
Area under the delay curve1.41.52.3-1.51.5-0.30.31.51.3-1.41.4
Delay disc. indifference point, 0s delay0.00.00.10.3-0.1-0.00.00.2-0.20.2-0.2
Delay disc. indifference point, 16s delay0.40.40.7-0.70.7-0.30.30.80.6-0.60.6
Delay disc. indifference point, 2s delay2.93.25.5-1.92.1-0.90.92.31.8-1.91.9
Delay disc. indifference point, 24s delay0.30.30.90.4-0.40.3-0.3-0.4-0.90.6-0.6
Delay disc. indifference point, 4s delay1.11.22.1-1.21.20.0-0.01.11.4-1.31.1
Delay disc. indifference point, 8s delay1.41.42.1-1.41.4-0.30.31.31.2-1.51.4
Delay discount exponential model param1.31.32.01.4-1.40.2-0.2-1.4-1.21.3-1.3
Delay discount hyperbolic model param1.41.52.21.4-1.50.2-0.2-1.5-1.21.4-1.3
Fecal boli incidents, locomotor time 10.30.30.5-0.70.60.4-0.40.50.7-0.60.6
Change in fecal boli incidents, locomotor task0.50.50.80.7-0.70.9-0.9-0.8-0.60.4-0.5
Time >=10cm from walls, locomotor time 10.60.60.80.9-0.80.8-0.8-0.6-0.50.7-0.9
Bouts of movement, locomotor time 10.30.30.50.5-0.5-0.60.6-0.4-0.70.6-0.7
Total resting periods, locomotor time 10.20.20.60.0-0.1-0.80.8-0.1-0.20.2-0.3
Rest time, locomotor task time 10.00.00.10.1-0.2-0.10.1-0.3-0.20.2-0.1
Distance moved, locomotor task time 10.30.30.50.7-0.60.4-0.4-0.4-0.70.6-0.6
Vertical activity count, locomotor time 10.80.91.21.1-1.00.9-0.9-0.7-1.00.9-0.9
Time >=10cm from walls, locomotor time 22.12.22.71.6-1.51.3-1.3-1.4-1.51.6-1.6
Bouts of movement, locomotor time 20.40.40.6-0.70.7-0.50.50.60.5-0.80.8
Total resting periods, locomotor time 20.60.60.8-0.80.8-0.70.70.70.6-0.80.9
Rest time, locomotor task time 20.80.91.4-1.00.9-0.90.90.71.2-0.91.0
Distance moved, locomotor task time 21.51.82.71.5-1.41.0-1.0-1.1-1.61.5-1.5
Vertical activity count, locomotor time 22.62.83.71.7-1.61.8-1.8-1.4-1.91.6-1.6
Weight adjusted by age4.34.85.32.2-2.22.3-2.3-2.1-2.12.2-2.2
Seeking ratio, delayed vs. immediate footshock0.70.81.3-0.70.8-1.11.10.80.9-0.70.7
Locomotion in novel chamber0.50.61.30.8-0.90.7-0.7-1.1-0.80.5-0.5
Locomotion in novel chamber post-restriction0.20.20.6-0.10.2-0.80.80.40.1-0.20.4
Progressive ratio0.40.41.00.6-0.60.3-0.3-0.7-0.60.8-1.0
Food seeking constrained by brief footshock3.44.15.91.8-1.82.4-2.4-1.8-1.82.0-2.0
Seeking ratio, punishment vs. effort0.10.10.30.1-0.00.6-0.60.0-0.10.00.2
Run reversals in cocaine runway, females0.00.00.1-0.0-0.0-0.30.3-0.10.10.0-0.3
Run reversals in cocaine runway, males1.31.31.6-1.21.2-1.01.01.31.0-1.11.0
Latency to leave start box in cocaine runway1.92.12.71.2-1.31.6-1.6-1.4-1.61.4-1.4
Latency to leave start box in cocaine runway, F2.42.63.41.5-1.61.3-1.3-1.8-1.81.6-1.8
Latency to leave start box in cocaine runway, M0.10.10.4-0.20.20.6-0.60.3-0.0-0.10.4
Cd content in liver0.20.20.6-0.50.50.1-0.10.40.3-0.80.8
Co content in liver0.30.40.90.7-0.60.3-0.3-0.4-0.60.8-0.9
Cu content in liver1.61.92.6-1.61.4-1.41.41.21.0-1.41.6
Fe content in liver0.00.00.1-0.10.1-0.20.20.3-0.2-0.30.3
K content in liver0.50.51.9-0.20.3-1.41.40.50.20.1-0.0
Mg content in liver1.01.02.0-0.90.9-1.41.41.11.0-0.40.5
Mn content in liver0.20.30.9-0.10.1-1.01.00.30.30.3-0.3
Na content in liver6.16.48.4-2.32.5-2.92.92.81.9-2.42.4
Rb content in liver0.50.60.8-0.80.8-0.70.70.90.8-0.70.7
Se content in liver0.91.01.81.1-1.10.3-0.3-1.0-1.11.3-1.2
Sr content in liver1.11.01.3-1.11.0-1.01.00.90.9-1.11.1
Zn content in liver0.00.00.1-0.10.0-0.30.30.0-0.1-0.00.1