Hub : Genes

Cyb5r3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009592 0.03 0.03 1.9e-03 0.02 0.02 0.01 0.02 2.9e-03 6.0e-03 7.7e-03 5.6e-03
2 Adipose mRNA stability ENSRNOG00000009592 0.05 0.04 4.8e-05 0.03 0.03 0.03 0.03 1.1e-04 2.4e-04 4.1e-04 2.0e-04
3 BLA gene expression ENSRNOG00000009592 0.3 0.11 0.0e+00 0.35 0.35 0.37 0.34 1.1e-19 8.6e-20 1.4e-20 7.0e-19
4 Brain gene expression ENSRNOG00000009592 0.11 0.05 0.0e+00 0.2 0.21 0.21 0.21 2.3e-18 4.3e-19 5.5e-19 4.8e-19
5 Liver gene expression ENSRNOG00000009592 0.16 0.08 0.0e+00 0.17 0.15 0.16 0.16 3.8e-18 9.9e-17 1.6e-17 6.9e-18
6 NAcc gene expression ENSRNOG00000009592 0.08 0.05 4.9e-06 0.07 0.07 0.06 0.07 7.6e-06 8.3e-06 1.5e-05 1.3e-05
7 PL gene expression ENSRNOG00000009592 0.16 0.08 5.6e-17 0.17 0.19 0.18 0.19 3.6e-13 1.4e-14 5.8e-14 3.8e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail1.75.46.5-2.32.52.22.32.42.42.2
BMI without tail0.51.12.0-0.91.40.70.91.11.10.9
Body weight1.66.68.4-2.72.92.72.62.12.22.7
Epididymis fat weight1.43.34.3-2.01.92.11.81.51.32.1
Glucose0.50.81.21.1-0.7-0.9-0.9-0.8-1.0-0.9
Heart weight2.84.06.0-2.41.72.32.21.51.61.9
Left kidney weight14.742.048.8-6.96.26.86.75.75.97.0
Right kidney weight16.145.950.2-7.06.77.16.96.26.47.0
Tail length0.00.10.30.10.2-0.2-0.2-0.5-0.4-0.1
Length with tail0.31.01.8-1.11.11.21.10.30.31.4
Length without tail0.51.12.0-1.00.91.31.10.50.61.4
Liver weight, left0.20.30.7-0.40.50.90.50.30.30.8
Liver weight, right0.40.71.8-0.90.61.30.70.30.31.1
Parametrial fat weight0.10.10.40.3-0.10.0-0.2-0.5-0.6-0.4
Retroperitoneal fat weight1.44.57.9-2.52.02.82.21.31.12.4
Intraocular pressure0.30.40.8-0.70.70.40.60.80.90.5
Extensor digitorum longus weight0.00.10.2-0.10.2-0.20.00.40.4-0.2
Soleus weight0.10.20.6-0.10.5-0.10.20.60.80.1
Tibialis anterior weight0.31.22.10.9-1.0-1.2-1.0-1.0-0.9-1.4
Tibia length1.02.73.7-1.71.51.81.81.31.41.9
Number of licking bursts0.10.10.30.4-0.3-0.5-0.4-0.4-0.3-0.4
Food consumed during 24 hour testing period2.42.93.7-1.71.91.51.71.81.71.6
Times rat made contact with spout1.71.92.9-1.21.71.11.31.51.51.1
Mean time between licks in bursts0.81.11.70.8-1.3-1.0-1.1-1.0-1.0-1.3
Mean num. licks in bursts1.92.22.6-1.51.61.51.51.61.51.4
Std. dev. time between licks in bursts0.60.81.10.7-1.1-0.8-0.7-1.0-1.0-0.6
Water consumed over 24 hours4.14.86.8-2.02.61.72.12.52.41.9
Indifference point 0 sec0.10.10.30.6-0.3-0.4-0.2-0.4-0.3-0.2
Indifference point AUC0.10.10.20.3-0.4-0.2-0.3-0.2-0.4-0.3
Indifference point function ln k1.21.72.5-1.31.61.21.31.11.11.4
Indifference point function log k1.21.72.5-1.31.61.21.31.11.11.4
Delay discounting total patch changes 0 sec0.10.20.50.7-0.4-0.5-0.3-0.4-0.4-0.4
Delay discounting total patch changes 12 sec0.10.10.20.00.10.20.30.50.40.4
Delay discounting total patch changes 18 sec0.00.00.1-0.2-0.2-0.00.0-0.4-0.30.1
Delay discounting total patch changes 24 sec0.10.20.40.7-0.5-0.4-0.4-0.3-0.3-0.4
Delay discounting total patch changes 6 sec0.00.00.1-0.00.00.30.30.10.00.1
Delay discounting time to switch 0 sec0.30.50.70.6-0.8-0.7-0.8-0.7-0.8-0.4
Delay discounting water rate 0 sec0.61.01.8-0.91.00.71.01.21.30.6
Delay discounting water rate 12 sec0.40.61.4-0.40.90.10.41.21.10.3
Delay discounting water rate 18 sec0.00.00.10.2-0.2-0.3-0.2-0.1-0.1-0.1
Delay discounting water rate 24 sec1.92.63.5-1.81.91.31.71.51.31.8
Delay discounting water rate 6 sec0.10.20.30.5-0.4-0.6-0.6-0.4-0.4-0.4
Locomotor activity2.74.35.2-2.31.92.32.11.71.92.3
Locomotor testing distance0.00.00.10.1-0.3-0.0-0.1-0.20.10.0
Locomotor testing rearing0.60.91.6-1.00.51.30.90.70.91.0
Light reinforcement 10.30.51.0-0.60.40.60.60.50.81.0
Light reinforcement 20.30.40.9-0.40.80.50.60.60.71.0
Reaction time number correct1.52.12.41.5-1.5-1.4-1.5-1.4-1.5-1.3
Reaction time mean minus median0.40.50.7-0.80.80.70.70.70.60.4
Reaction time mean minus median AUC0.81.11.7-1.11.10.90.91.31.10.6
Reaction time num false alarms0.00.00.1-0.2-0.10.30.1-0.10.20.3
Reaction time num false alarms AUC0.00.00.1-0.2-0.10.30.1-0.10.30.3
Reaction time trials correct on left1.52.12.41.5-1.5-1.4-1.5-1.4-1.5-1.3
Reaction time trials on left1.52.22.41.6-1.5-1.4-1.5-1.4-1.5-1.3
Reaction time mean0.00.00.1-0.2-0.0-0.2-0.1-0.0-0.2-0.2
Reaction time mean AUC0.00.00.1-0.1-0.1-0.2-0.2-0.0-0.2-0.3
Median of all reaction times0.10.10.20.1-0.4-0.5-0.4-0.3-0.5-0.4
Reaction time omissions0.10.20.4-0.0-0.6-0.4-0.4-0.3-0.5-0.5
Reaction time false alarm rate0.40.50.8-0.80.60.80.80.50.90.7
Reaction time premature initiation rate0.00.00.10.00.10.20.1-0.2-0.00.4
Reaction time premature initiations0.20.30.50.6-0.5-0.3-0.5-0.7-0.7-0.2
Std. dev. reaction times0.40.61.1-1.10.70.90.80.60.30.6
Reaction time trials completed1.52.22.41.6-1.5-1.4-1.5-1.4-1.5-1.3
Reaction time trials AUC1.11.61.91.4-1.3-1.2-1.3-1.3-1.4-1.1
Social response proportion0.30.30.5-0.70.70.50.60.70.30.4
Social responses0.10.10.5-0.2-0.30.2-0.1-0.4-0.70.1
Social time2.22.93.61.5-1.7-1.8-1.7-1.5-1.9-1.7
Conditioned locomotion0.10.10.2-0.40.30.40.20.10.00.3
Cocaine response after cond. corrected0.00.00.0-0.0-0.10.10.00.00.20.0
Cocaine response after cond. not corrected0.00.00.1-0.1-0.10.20.00.10.20.0
Cocaine response before conditioning0.10.10.10.3-0.3-0.2-0.3-0.2-0.3-0.3
Saline control response0.30.30.6-0.40.80.80.50.40.40.6
Condit. Reinf. active minus inactive responses0.10.10.3-0.30.30.30.40.0-0.00.5
Condit. Reinf. active-inactive response ratio0.20.20.4-0.50.40.40.5-0.00.10.7
Condit. Reinf. active responses0.81.11.8-1.00.91.11.10.90.81.3
Condit. Reinf. inactive responses0.81.01.5-0.90.91.01.01.21.01.1
Condit. Reinf. lever presses0.10.10.40.4-0.6-0.3-0.2-0.3-0.3-0.1
Condit. Reinf. lever reinforcers received0.20.30.8-0.50.40.70.70.30.20.9
Pavlov. Cond. lever latency0.20.20.5-0.60.70.50.30.50.50.1
Pavlov. Cond. magazine entry latency3.03.54.22.0-2.1-1.9-1.7-1.8-1.9-1.7
Pavlov. Cond. change in total contacts0.10.20.40.6-0.6-0.1-0.1-0.5-0.50.1
Pavlov. Cond. index score1.41.82.51.5-1.6-1.3-1.2-1.3-1.4-1.0
Pavlov. Cond. latency score1.72.22.91.7-1.7-1.5-1.3-1.4-1.5-1.2
Pavlov. Cond. lever contacts0.20.30.50.7-0.7-0.6-0.4-0.5-0.5-0.1
Pavlov. Cond. magazine entry number1.82.23.1-1.61.81.41.31.51.51.2
Pavlov. Cond. intertrial magazine entries2.63.34.4-2.11.81.81.91.81.91.5
Pavlov. Cond. lever-magazine prob. diff.1.62.12.91.7-1.7-1.4-1.3-1.4-1.5-1.1
Pavlov. Cond. response bias0.40.61.00.9-1.0-0.7-0.6-0.7-0.8-0.3
Conditioned reinforcement - actives0.20.10.40.1-0.40.3-0.1-0.6-0.6-0.1
Conditioned reinforcement - inactives0.00.00.10.3-0.2-0.0-0.1-0.2-0.1-0.2
Conditioned locomotion0.81.01.7-1.10.91.31.10.60.91.0
Intermittent access intake day 1-15 change0.60.61.00.4-0.9-0.6-0.7-0.8-1.0-0.7
Intermittent access intake escalation0.40.40.80.4-0.8-0.6-0.6-0.6-0.9-0.6
Intermittent access intake escalation 20.10.10.20.2-0.4-0.3-0.3-0.3-0.5-0.3
Intermitt. access day 1 inactive lever presses0.90.91.2-0.80.91.01.01.01.10.9
Intermitt. access day 15 inactive lever presses0.70.81.1-0.90.61.11.10.80.80.9
Intermitt. access escalation Index0.10.10.20.3-0.3-0.0-0.2-0.3-0.4-0.2
Intermittent access day 1 total infusions0.60.70.9-0.90.91.00.90.60.80.9
Intermittent access day 15 total infusions0.00.00.0-0.10.10.10.20.20.20.1
Intermittent access terminal intake (last 3 days)0.00.00.0-0.1-0.0-0.0-0.00.10.1-0.1
Intermittent access total infusions0.10.10.3-0.30.30.30.30.40.50.3
Intermittent access day 1 locomotion0.10.10.2-0.40.30.40.3-0.10.10.3
Intermittent access day 15 total locomotion0.10.10.2-0.40.20.20.30.30.50.2
Intermittent access total locomotion0.20.20.5-0.30.40.40.40.60.70.3
Intermittent access standard deviation0.40.40.8-0.90.60.70.70.60.60.6
Cocaine induced anxiety2.32.74.8-1.21.61.01.52.22.11.4
Post-drug Anxiety1.71.92.8-1.11.60.91.31.71.61.3
Baseline Anxiety1.92.03.91.0-1.0-1.1-1.3-2.0-2.0-1.2
Lifetime Intake0.40.50.8-0.60.60.70.70.80.90.7
Incentive Sensitization - Responses0.40.41.1-0.10.5-0.10.31.01.00.2
Incentive Sensitization - Breakpoint0.50.51.3-0.20.60.10.51.11.10.3
Progressive ratio test 1 active lever presses0.10.10.1-0.30.20.30.3-0.2-0.10.3
Progressive ratio test 1 breakpoint0.10.10.3-0.0-0.10.0-0.1-0.6-0.4-0.1
Progressive ratio test 1 inactive lever presses0.00.00.1-0.1-0.10.30.30.20.20.1
Progressive ratio test 2 active lever presses0.00.00.20.00.2-0.10.10.30.4-0.0
Progressive ratio test 2 breakpoint0.10.10.1-0.20.30.10.30.30.40.2
Progressive ratio test 2 inactive lever presses0.00.00.10.3-0.1-0.3-0.10.0-0.0-0.2
Total sessions with >9 infusions0.70.71.3-0.80.71.21.00.50.61.0
Short access day 1 total inactive lever presses2.62.93.7-1.51.51.81.81.81.91.7
Short access day 10 total inactive lever presses2.52.83.8-1.51.81.31.62.01.91.6
Short access day 1 total infusions1.51.62.1-1.11.11.41.41.31.31.3
Short access day 10 total infusions0.10.10.4-0.0-0.10.30.1-0.6-0.40.1
Short access total infusions1.11.21.6-1.11.01.21.21.01.11.2
Short access day 1 locomotion0.10.10.30.2-0.5-0.0-0.10.10.3-0.2
Short access day 10 total locomotion0.80.91.70.7-1.3-0.7-0.9-0.9-0.8-1.0
Short access total locomotion0.10.10.2-0.4-0.40.40.2-0.3-0.10.2
Compulsive drug intake0.40.40.70.6-0.9-0.8-0.7-0.5-0.3-0.7
One hour access (0.3 mA shock)0.40.50.80.8-0.7-0.9-0.7-0.4-0.2-0.8
One hour access (shock baseline)0.30.30.70.8-0.4-0.7-0.6-0.3-0.2-0.6
Number of responses in last shaping day0.90.91.30.9-1.0-0.9-0.8-1.0-1.1-0.8
Context. condit. distance diff. score5.77.08.0-2.62.42.82.62.72.82.5
Locomotion velocity, session 10.70.81.4-0.70.80.70.80.91.01.2
Locomotion distance, session 10.70.92.31.2-0.8-1.5-1.1-0.5-0.3-0.9
Locomotion velocity, session 20.91.01.5-0.81.00.70.91.21.11.2
Locomotion distance, session 21.31.92.91.6-1.2-1.7-1.4-1.2-1.0-1.4
Locomotion velocity, session 30.50.61.2-0.30.90.40.51.11.10.8
Locomotion distance, session 31.11.21.91.2-1.0-1.4-1.3-0.7-0.6-1.3
Stereotopy head waving bouts, day 31.01.21.9-0.91.11.31.11.10.71.4
Stereotopy head waving duration, day 35.26.37.9-2.32.62.62.52.52.22.8
Locomotion velocity, session 70.10.10.10.30.1-0.3-0.20.40.2-0.1
Locomotion distance, session 71.11.42.01.4-1.1-1.3-1.3-1.0-0.9-1.2
Stereotopy head waving bouts, day 75.25.87.6-2.52.42.42.32.42.22.8
Stereotopy head waving duration, day 73.34.05.1-2.12.11.91.92.01.82.3
Locomotion velocity, session 86.57.88.6-2.92.82.52.72.92.92.7
Locomotion distance, session 81.01.42.1-1.21.11.21.11.21.41.1
Degree of sensitization distance0.90.91.2-1.00.91.11.10.80.81.1
Degree of sensitization stereotypy3.53.84.4-2.11.91.81.82.01.92.1
Condit. Reinf. active minus inactive responses1.31.42.50.9-1.4-0.7-1.0-1.6-1.6-0.8
Condit. Reinf. active-inactive response ratio0.10.10.2-0.30.00.40.3-0.1-0.10.5
Condit. Reinf. active responses3.44.15.71.8-2.3-1.6-1.9-2.4-2.2-1.9
Condit. Reinf. inactive responses3.94.75.32.2-2.2-2.2-2.1-2.1-1.9-2.3
Incentive salience index mean2.12.53.91.3-1.8-1.3-1.4-2.0-1.9-1.3
Condit. Reinf. lever presses2.22.93.81.5-1.8-1.6-1.7-2.0-1.8-1.5
Time in familiar zone, hab. session 10.10.10.3-0.10.30.10.20.40.50.3
Time in novel zone, hab. session 11.41.42.0-1.41.11.41.21.11.00.9
Total zone transitions, hab. session 12.23.14.02.0-1.5-2.0-1.8-1.7-1.6-1.7
Total locomotion distance, hab. session 10.50.71.11.0-0.7-1.1-1.0-0.8-0.8-0.6
Locomotion velocity, hab. session 10.91.22.01.3-0.9-1.4-1.2-1.0-1.0-0.8
Time in familiar zone, hab. session 20.10.10.20.2-0.4-0.4-0.4-0.4-0.5-0.3
Time in novel zone, hab. session 21.01.01.2-0.91.11.11.11.10.90.9
Total zone transitions, hab. session 20.10.10.30.5-0.3-0.6-0.4-0.1-0.1-0.2
Total locomotion distance, hab. session 20.20.20.50.6-0.4-0.7-0.5-0.4-0.4-0.4
Locomotion velocity, hab. session 20.50.71.31.0-0.7-1.1-0.9-0.7-0.7-0.7
Novel to familiar place preference ratio3.94.16.7-2.31.92.62.11.61.51.9
Novelty place preference5.05.28.2-2.62.12.92.41.91.82.1
Time in novel zone, NPP test6.56.810.1-2.92.53.22.72.22.22.4
Total zone transitions, NPP test0.81.22.31.2-1.0-1.5-1.2-0.9-0.7-1.1
Total locomotion distance, NPP test0.30.51.00.7-0.6-1.0-0.7-0.5-0.4-0.6
Locomotion velocity, NPP test1.42.03.01.5-1.3-1.7-1.5-1.3-1.2-1.3
Pavlov. Cond. lever latency2.73.44.8-1.71.91.71.72.12.21.5
Pavlov. Cond. magazine entry latency2.32.93.71.6-1.6-1.6-1.6-1.8-1.9-1.7
Pavlov. Cond. change in total contacts2.42.63.71.4-1.6-1.5-1.4-1.8-1.9-1.5
Pavlov. Cond. index score1.62.13.21.3-1.4-1.3-1.3-1.6-1.8-1.3
Pavlov. Cond. latency score1.31.72.71.1-1.3-1.1-1.2-1.5-1.7-1.2
Pavlov. Cond. lever contacts3.33.95.21.8-1.9-1.9-1.9-2.2-2.3-1.8
Pavlov. Cond. magazine entry number2.02.53.7-1.41.51.51.51.71.91.6
Pavlov. Cond. intertrial magazine entries0.40.40.60.6-0.8-0.7-0.6-0.6-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.2.32.83.91.6-1.6-1.6-1.6-1.8-2.0-1.6
Pavlov. Cond. response bias3.34.15.61.9-1.9-1.9-1.9-2.2-2.4-1.9
Bone: apparent density0.30.50.60.7-0.5-0.6-0.7-0.8-0.7-0.6
Bone surface0.00.00.10.10.10.30.1-0.1-0.00.4
Bone volume0.00.00.00.10.00.2-0.0-0.2-0.10.2
Bone: connectivity density0.10.10.20.3-0.1-0.3-0.4-0.4-0.5-0.3
Bone: cortical apparent density1.31.62.21.1-1.4-1.2-1.2-1.5-1.5-1.1
Bone: cortical area1.72.63.2-1.61.61.81.71.31.51.7
Bone: cortical porosity0.50.61.0-0.70.80.70.71.00.70.8
Bone: cortical porosity1.31.41.6-1.21.11.31.21.31.11.3
Bone: cortical thickness0.10.10.3-0.50.50.40.5-0.0-0.10.3
Bone: cortical thickness0.30.30.6-0.80.60.50.70.50.50.3
Bone: cortical tissue density1.21.52.11.0-1.3-1.1-1.2-1.4-1.4-1.1
Bone: elastic displacement1.21.41.5-1.11.21.11.11.21.21.2
Bone: elastic work4.65.96.1-2.52.42.52.42.42.52.4
Bone: endosteal estimation2.14.57.0-1.61.82.11.92.32.72.3
Bone: endosteal perimeter2.04.05.2-1.71.72.21.82.02.22.3
Bone: final force1.11.82.5-1.41.11.61.41.01.31.4
Bone: final moment1.72.83.6-1.71.51.91.81.41.71.7
Bone: marrow area2.35.07.6-1.71.92.22.02.52.82.4
Bone: maximum diameter5.710.511.6-3.13.13.43.23.23.33.4
Bone: maximum force2.95.16.1-2.32.22.52.32.02.22.2
Bone: maximum moment3.86.67.7-2.62.52.82.72.42.62.6
Bone: minimum diameter0.71.31.9-1.10.91.31.11.01.21.4
Bone: periosteal estimation2.75.66.8-2.12.22.52.32.32.62.5
Bone: periosteal perimeter3.65.97.2-2.32.22.72.42.32.42.7
Bone: post-yield work0.60.81.4-0.81.00.80.91.01.20.7
Bone: stiffness1.21.92.3-1.41.31.51.51.11.41.4
Bone: tissue strength0.40.40.6-0.70.40.70.70.60.70.8
Bone: trabecular number0.10.10.30.5-0.3-0.3-0.5-0.3-0.3-0.4
Bone: trabecular spacing0.81.01.4-1.20.91.01.10.91.01.0
Bone: trabecular thickness0.30.40.80.6-0.5-0.4-0.5-0.6-0.9-0.4
Bone: trabecular tissue density0.60.81.20.7-1.1-0.8-0.7-1.1-1.0-0.9
Breakpoint value in progressive ratio session0.10.10.2-0.20.40.10.30.10.10.3
Distance traveled before self-admin0.20.20.30.4-0.5-0.6-0.40.30.1-0.4
Distance traveled after self-admin0.40.40.9-0.50.50.60.61.00.70.5
Delta time in closed arm before/after self-admin0.10.10.5-0.4-0.10.70.3-0.00.10.2
Delta time in open arm before/after self-admin0.20.20.70.10.1-0.4-0.10.80.8-0.0
Diff in mean of infusions in LGA sessions0.91.11.50.7-1.2-0.8-1.0-1.1-1.1-1.0
Extinction: sum of active levers before priming0.20.20.50.5-0.7-0.1-0.3-0.6-0.1-0.4
Active lever presses in extinction session 60.50.40.6-0.70.70.50.70.70.60.7
Delta distance traveled before/after self-admin2.22.32.8-1.51.71.61.51.41.31.5
Delta ambulatory time before/after self-admin3.43.74.7-2.12.22.02.01.61.62.0
Time in closed arm before self-admin3.13.54.82.0-1.7-2.2-1.9-1.6-1.7-1.9
Time in closed arm after self-admin0.10.10.2-0.3-0.10.2-0.0-0.5-0.5-0.0
Time in open arm before self-admin0.10.10.20.3-0.3-0.2-0.4-0.4-0.2-0.3
Time in open arm after self-admin0.30.30.50.7-0.3-0.7-0.50.40.6-0.5
Sum of active levers in priming session hrs 5-60.00.00.10.1-0.3-0.1-0.10.20.2-0.1
Time to tail flick, vehicle, before self-admin0.20.20.5-0.60.50.70.50.20.20.5
Time to tail flick, vehicle, after self-admin0.30.40.80.1-0.9-0.6-0.8-0.4-0.4-0.7
Time to tail flick, test, before self-admin0.00.00.1-0.10.10.00.00.10.30.1
Time to tail flick, test, after self-admin2.82.83.71.9-1.9-1.5-1.7-1.6-1.2-1.8
Delta time to tail flick, vehicle, before/after SA0.10.10.20.1-0.5-0.3-0.20.20.4-0.3
Delta time to tail flick, test, before/after SA3.02.73.81.9-1.8-1.4-1.6-1.5-1.3-1.8
Ambulatory time before self-admin0.10.10.30.2-0.3-0.4-0.20.60.4-0.3
Ambulatory time after self-admin0.20.30.8-0.30.40.20.30.90.70.2
Total heroin consumption0.30.30.7-0.30.50.40.60.60.90.6
Area under the delay curve1.71.82.41.2-1.5-0.9-1.3-1.6-1.5-1.3
Delay disc. indifference point, 0s delay0.30.30.4-0.40.50.60.60.50.60.5
Delay disc. indifference point, 16s delay3.33.34.51.5-2.0-1.5-1.8-2.1-2.0-1.7
Delay disc. indifference point, 2s delay0.40.40.70.8-0.6-0.4-0.6-0.6-0.6-0.7
Delay disc. indifference point, 24s delay0.50.50.80.5-0.8-0.4-0.7-0.9-0.8-0.6
Delay disc. indifference point, 4s delay0.10.10.30.3-0.50.2-0.2-0.3-0.3-0.3
Delay disc. indifference point, 8s delay2.93.03.51.6-1.9-1.5-1.7-1.9-1.9-1.7
Delay discount exponential model param1.61.72.3-1.21.50.91.21.51.51.3
Delay discount hyperbolic model param1.11.21.6-1.01.30.71.11.31.21.1
Fecal boli incidents, locomotor time 10.20.30.50.7-0.6-0.6-0.5-0.2-0.1-0.5
Change in fecal boli incidents, locomotor task0.60.61.0-1.00.90.70.70.60.50.8
Time >=10cm from walls, locomotor time 10.00.00.10.2-0.3-0.1-0.10.00.20.0
Bouts of movement, locomotor time 10.10.10.20.0-0.4-0.2-0.3-0.2-0.4-0.4
Total resting periods, locomotor time 10.30.30.40.3-0.6-0.5-0.6-0.4-0.6-0.7
Rest time, locomotor task time 10.10.10.10.4-0.2-0.3-0.20.1-0.1-0.3
Distance moved, locomotor task time 10.30.30.8-0.60.40.90.5-0.00.20.7
Vertical activity count, locomotor time 10.10.10.1-0.30.20.40.2-0.10.10.3
Time >=10cm from walls, locomotor time 20.40.40.50.6-0.7-0.6-0.7-0.6-0.7-0.6
Bouts of movement, locomotor time 20.10.10.40.0-0.4-0.1-0.2-0.5-0.7-0.2
Total resting periods, locomotor time 20.10.10.5-0.0-0.4-0.1-0.2-0.6-0.7-0.2
Rest time, locomotor task time 20.20.20.30.5-0.3-0.5-0.4-0.4-0.6-0.4
Distance moved, locomotor task time 20.60.70.9-1.00.80.80.80.90.90.8
Vertical activity count, locomotor time 20.70.81.1-1.10.90.70.90.80.90.9
Weight adjusted by age0.10.10.2-0.30.30.40.30.30.40.3
Seeking ratio, delayed vs. immediate footshock3.03.55.92.4-1.6-2.4-1.9-1.1-1.3-2.0
Locomotion in novel chamber0.20.20.40.4-0.2-0.5-0.6-0.4-0.6-0.4
Locomotion in novel chamber post-restriction1.21.42.41.2-1.2-1.5-1.3-0.9-0.8-1.2
Progressive ratio0.00.00.10.2-0.2-0.0-0.1-0.3-0.2-0.1
Food seeking constrained by brief footshock0.91.11.6-1.11.01.21.10.70.81.2
Seeking ratio, punishment vs. effort0.30.30.4-0.60.60.60.60.50.50.6
Run reversals in cocaine runway, females1.61.62.71.1-1.0-1.1-1.3-1.4-1.6-1.0
Run reversals in cocaine runway, males1.31.31.6-1.11.20.91.11.21.31.1
Latency to leave start box in cocaine runway0.30.41.0-0.40.60.20.40.81.00.4
Latency to leave start box in cocaine runway, F0.20.20.40.5-0.3-0.6-0.50.10.3-0.5
Latency to leave start box in cocaine runway, M1.51.41.7-1.21.31.21.31.11.11.1
Cd content in liver1.92.13.7-1.91.41.61.51.31.41.1
Co content in liver0.70.81.1-1.01.01.01.00.80.80.6
Cu content in liver5.87.08.62.5-2.8-2.4-2.6-2.8-2.9-2.4
Fe content in liver0.40.50.7-0.70.70.80.60.60.60.9
K content in liver0.30.30.70.7-0.5-0.4-0.4-0.7-0.8-0.2
Mg content in liver0.90.91.41.2-0.8-0.9-0.8-1.1-1.2-0.6
Mn content in liver0.00.00.1-0.10.20.20.10.10.10.3
Na content in liver2.42.53.41.8-1.3-1.8-1.6-1.4-1.4-1.6
Rb content in liver0.00.00.1-0.20.20.30.2-0.1-0.20.3
Se content in liver1.11.42.11.2-1.3-0.8-1.1-1.4-1.4-0.8
Sr content in liver1.11.01.90.9-0.8-1.1-1.0-0.9-0.9-1.4
Zn content in liver0.80.91.20.8-1.0-1.0-0.9-1.0-1.1-0.9