Hub : Genes

Tcf20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009585 0.11 0.06 3.9e-08 0.06 0.06 0.06 0.06 5.9e-07 3.8e-07 4.8e-07 9.4e-07
2 Adipose mRNA stability ENSRNOG00000009585 0.02 0.02 3.2e-03 0 0.01 0 0 1.5e-01 7.2e-02 3.6e-01 2.0e-01
3 BLA gene expression ENSRNOG00000009585 0.17 0.08 2.4e-09 0.11 0.15 0.14 0.13 1.8e-06 1.3e-08 5.7e-08 1.7e-07
4 Brain gene expression ENSRNOG00000009585 0.33 0.11 0.0e+00 0.43 0.46 0.45 0.46 4.2e-43 7.0e-47 4.2e-46 1.3e-46
5 Brain mRNA stability ENSRNOG00000009585 0.06 0.03 7.0e-05 0.01 0.04 0.03 0.03 2.1e-02 1.1e-04 8.8e-04 8.7e-04
6 IL gene expression ENSRNOG00000009585 0.26 0.12 2.1e-04 0.11 0.11 0.1 0.09 1.4e-03 1.1e-03 1.8e-03 3.5e-03
7 LHb gene expression ENSRNOG00000009585 0.41 0.17 2.1e-05 0.13 0.17 0.17 0.16 4.9e-04 8.9e-05 6.7e-05 9.9e-05
8 Liver gene expression ENSRNOG00000009585 0.52 0.18 0.0e+00 0.14 0.15 0.16 0.16 2.4e-15 1.4e-16 3.8e-17 7.0e-17
9 Liver mRNA stability ENSRNOG00000009585 0.03 0.02 9.2e-03 0.02 0.02 0.01 0.02 1.2e-03 5.2e-03 3.7e-02 2.7e-03
10 NAcc gene expression ENSRNOG00000009585 0.11 0.06 6.2e-09 0.11 0.11 0.12 0.11 1.2e-08 2.8e-08 6.0e-09 2.4e-08
11 OFC gene expression ENSRNOG00000009585 0.16 0.1 5.5e-03 0.08 0.05 0.02 0.01 6.6e-03 3.1e-02 1.4e-01 2.1e-01
12 PL gene expression ENSRNOG00000009585 0.33 0.17 0.0e+00 0.2 0.2 0.21 0.15 4.8e-15 3.4e-15 6.2e-16 2.4e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.82.75.6-0.9-2.4-1.8-2.0-1.4-1.3-2.1-0.5-1.1-1.1-2.2-1.8
BMI without tail0.20.30.50.1-0.5-0.7-0.6-0.6-0.5-0.7-0.7-0.7-0.3-0.6-0.4
Body weight1.25.37.20.0-2.5-2.6-2.7-2.4-2.3-2.6-1.3-2.2-2.3-2.7-2.6
Epididymis fat weight2.55.89.11.6-1.8-2.5-2.6-2.8-3.0-2.3-2.5-3.0-1.8-2.3-2.2
Glucose0.50.81.1-0.40.71.01.01.00.91.10.80.60.81.01.0
Heart weight2.43.47.2-1.4-2.5-1.8-2.0-1.1-0.9-2.7-0.3-0.9-2.3-2.5-2.2
Left kidney weight11.332.447.2-0.5-6.6-6.6-6.9-6.1-5.8-6.2-2.0-4.4-5.6-6.6-6.7
Right kidney weight11.833.848.4-0.8-6.8-6.7-6.9-6.0-5.7-6.6-2.2-4.5-5.8-7.0-6.8
Tail length0.10.20.50.70.6-0.00.2-0.1-0.10.0-0.7-0.7-0.20.30.2
Length with tail0.51.72.60.6-0.9-1.5-1.4-1.6-1.6-1.1-0.7-1.5-1.6-1.2-1.5
Length without tail0.71.42.6-0.3-1.4-1.3-1.4-1.3-1.3-0.90.2-0.6-1.3-1.5-1.6
Liver weight, left1.32.03.51.7-0.3-1.2-1.2-1.7-1.9-0.7-1.6-1.8-1.7-1.0-1.4
Liver weight, right2.43.97.32.3-0.7-1.8-1.8-2.4-2.7-1.2-2.3-2.7-1.6-1.4-1.7
Parametrial fat weight0.00.10.2-0.4-0.20.30.10.40.4-0.20.10.1-0.1-0.3-0.1
Retroperitoneal fat weight2.06.69.10.7-2.6-2.7-3.0-2.8-3.0-2.7-1.7-2.7-2.0-3.0-2.8
Intraocular pressure0.20.30.50.5-0.3-0.6-0.6-0.6-0.6-0.5-0.5-0.7-0.2-0.3-0.3
Extensor digitorum longus weight0.00.10.20.10.30.10.20.20.3-0.1-0.40.0-0.30.20.1
Soleus weight0.10.20.7-0.8-0.10.30.30.50.60.10.70.60.60.10.2
Tibialis anterior weight0.51.84.5-1.20.91.61.62.02.10.60.71.31.01.11.3
Tibia length0.82.34.0-0.3-1.8-1.8-1.8-1.7-1.5-1.4-0.1-0.9-1.7-1.7-2.0
Number of licking bursts0.10.20.30.00.50.40.50.40.50.40.00.30.30.60.5
Food consumed during 24 hour testing period1.01.22.8-0.8-1.7-1.3-1.4-0.9-0.8-1.20.0-0.5-1.1-1.3-1.2
Times rat made contact with spout0.70.81.8-0.7-1.2-0.8-0.9-0.5-0.4-1.3-0.3-0.5-1.2-1.2-1.0
Mean time between licks in bursts0.50.71.20.11.01.11.11.11.10.5-0.00.50.41.01.0
Mean num. licks in bursts1.31.62.6-0.1-1.4-1.3-1.4-1.1-1.1-1.6-0.7-1.1-1.5-1.6-1.5
Std. dev. time between licks in bursts1.01.22.4-1.10.51.01.01.11.21.11.51.51.01.00.9
Water consumed over 24 hours1.72.04.4-0.4-1.6-1.6-1.5-1.2-1.0-1.8-0.6-1.0-2.1-1.5-1.6
Indifference point 0 sec0.40.72.0-1.20.10.60.50.70.90.61.41.20.80.30.2
Indifference point AUC0.00.00.1-0.10.30.30.30.20.20.40.20.20.10.20.1
Indifference point function ln k0.81.21.70.1-1.1-1.3-1.3-1.2-1.2-1.2-0.4-0.9-1.0-1.2-1.3
Indifference point function log k0.81.21.70.1-1.1-1.3-1.3-1.2-1.2-1.2-0.4-0.9-1.0-1.2-1.3
Delay discounting total patch changes 0 sec0.40.71.8-1.10.20.70.70.91.00.61.31.20.80.40.3
Delay discounting total patch changes 12 sec0.20.21.0-0.9-0.40.0-0.10.00.10.31.00.60.3-0.2-0.3
Delay discounting total patch changes 18 sec0.40.62.4-1.3-0.30.30.30.50.60.41.51.10.60.10.1
Delay discounting total patch changes 24 sec0.20.30.9-0.20.40.50.50.40.40.60.60.61.00.40.4
Delay discounting total patch changes 6 sec0.20.31.4-1.2-0.40.00.10.30.5-0.10.60.6-0.3-0.4-0.4
Delay discounting time to switch 0 sec0.30.41.30.50.60.40.40.1-0.11.20.40.41.10.90.8
Delay discounting water rate 0 sec0.30.51.7-1.2-0.7-0.4-0.30.10.5-1.10.10.1-1.3-0.9-0.7
Delay discounting water rate 12 sec0.00.00.2-0.10.2-0.10.10.00.2-0.2-0.10.1-0.4-0.1-0.2
Delay discounting water rate 18 sec0.20.20.5-0.40.50.40.50.40.60.40.50.7-0.30.30.1
Delay discounting water rate 24 sec0.60.91.6-1.2-1.3-1.1-1.0-0.7-0.4-1.00.30.1-0.8-1.1-1.1
Delay discounting water rate 6 sec0.20.20.90.70.90.30.50.00.00.5-0.4-0.3-0.50.60.3
Locomotor activity2.84.57.00.5-1.9-2.4-2.3-2.4-2.3-2.1-1.3-2.2-2.6-2.3-2.4
Locomotor testing distance0.00.00.30.10.10.00.0-0.1-0.10.1-0.1-0.4-0.5-0.0-0.1
Locomotor testing rearing1.32.13.50.8-1.0-1.3-1.4-1.4-1.5-1.4-1.5-1.9-1.8-1.5-1.3
Light reinforcement 10.51.02.31.2-0.2-1.1-0.9-1.4-1.5-0.3-0.6-1.3-0.9-0.5-0.9
Light reinforcement 20.30.41.40.7-0.5-0.7-0.8-1.0-1.2-0.1-0.3-0.7-0.1-0.3-0.4
Reaction time number correct0.71.03.21.51.80.91.10.40.31.2-0.9-0.00.31.21.0
Reaction time mean minus median0.81.03.20.7-0.4-0.8-0.7-0.7-0.6-1.3-1.6-1.1-1.8-0.7-0.8
Reaction time mean minus median AUC0.91.22.80.6-0.7-1.0-0.9-0.7-0.7-1.5-1.7-1.2-1.6-0.9-0.8
Reaction time num false alarms0.60.92.61.60.3-0.7-0.5-1.0-1.1-0.2-1.6-0.9-1.0-0.3-0.6
Reaction time num false alarms AUC0.60.92.61.50.3-0.7-0.5-1.0-1.1-0.2-1.6-0.8-1.2-0.3-0.6
Reaction time trials correct on left0.71.03.21.51.80.91.10.40.31.2-0.9-0.00.31.21.0
Reaction time trials on left0.81.13.41.51.80.91.10.40.21.2-1.0-0.00.31.21.0
Reaction time mean0.10.10.3-0.20.20.20.20.30.4-0.1-0.20.5-0.30.20.2
Reaction time mean AUC0.10.10.3-0.10.20.30.30.40.40.0-0.20.5-0.10.30.3
Median of all reaction times0.30.41.1-0.40.40.60.60.70.70.50.41.10.40.60.6
Reaction time omissions0.20.21.10.70.60.20.30.10.1-0.2-1.1-0.4-0.40.40.5
Reaction time false alarm rate0.50.61.00.5-0.6-0.9-0.9-0.9-0.9-0.7-0.9-0.6-1.0-0.8-0.8
Reaction time premature initiation rate0.50.63.0-1.4-0.40.20.10.30.40.71.71.30.2-0.0-0.2
Reaction time premature initiations0.30.41.2-0.70.40.60.60.40.51.01.01.10.30.40.2
Std. dev. reaction times0.81.13.40.5-0.7-1.0-1.0-0.9-0.8-1.3-1.3-0.9-1.8-1.0-1.0
Reaction time trials completed0.81.13.41.51.80.91.10.40.21.2-1.0-0.00.31.21.0
Reaction time trials AUC0.60.82.61.41.60.81.00.20.11.1-0.9-0.00.21.10.8
Social response proportion0.30.31.2-1.1-0.7-0.1-0.20.20.4-0.60.70.40.0-0.4-0.3
Social responses0.10.20.40.50.1-0.3-0.3-0.5-0.5-0.1-0.6-0.6-0.6-0.1-0.2
Social time2.02.74.0-0.41.51.91.81.81.71.80.91.61.71.82.0
Conditioned locomotion0.80.91.91.3-0.2-0.7-0.7-1.0-1.2-0.7-1.3-1.4-0.9-0.5-0.7
Cocaine response after cond. corrected0.10.20.40.50.1-0.3-0.2-0.4-0.4-0.2-0.6-0.7-0.5-0.2-0.2
Cocaine response after cond. not corrected0.20.20.70.70.1-0.3-0.3-0.5-0.6-0.2-0.7-0.8-0.7-0.2-0.2
Cocaine response before conditioning0.10.10.20.20.20.20.20.10.10.50.20.10.10.40.4
Saline control response1.21.64.31.4-0.1-1.1-0.9-1.3-1.4-0.7-1.4-1.6-2.1-0.8-1.2
Condit. Reinf. active minus inactive responses0.50.62.3-1.5-0.70.0-0.10.30.40.21.51.00.7-0.1-0.0
Condit. Reinf. active-inactive response ratio0.80.93.5-1.9-0.90.0-0.10.30.50.21.81.30.8-0.2-0.2
Condit. Reinf. active responses0.50.71.6-0.7-1.3-1.0-1.1-0.9-0.8-0.50.6-0.1-0.4-0.9-0.9
Condit. Reinf. inactive responses0.91.12.00.6-0.9-1.2-1.2-1.3-1.4-0.8-0.6-1.2-1.0-0.9-1.0
Condit. Reinf. lever presses0.40.62.2-1.1-0.10.40.40.50.60.91.51.00.80.50.5
Condit. Reinf. lever reinforcers received0.30.41.0-0.9-1.0-0.6-0.7-0.5-0.4-0.11.00.3-0.1-0.5-0.6
Pavlov. Cond. lever latency0.60.92.61.2-0.2-0.6-0.6-0.6-0.8-1.1-1.6-1.4-0.9-0.6-0.5
Pavlov. Cond. magazine entry latency4.85.58.5-2.51.22.42.32.62.82.22.92.92.11.81.8
Pavlov. Cond. change in total contacts1.72.38.5-2.8-0.50.80.61.11.31.02.92.40.90.1-0.0
Pavlov. Cond. index score2.73.67.3-2.20.71.81.71.92.11.92.72.51.71.41.3
Pavlov. Cond. latency score3.44.48.3-2.40.82.01.92.22.42.02.92.72.01.51.5
Pavlov. Cond. lever contacts0.91.34.3-1.40.10.70.70.70.91.42.11.71.20.80.6
Pavlov. Cond. magazine entry number3.13.87.52.3-0.7-1.9-1.7-2.0-2.2-1.9-2.7-2.6-1.9-1.3-1.3
Pavlov. Cond. intertrial magazine entries1.51.94.7-0.5-1.9-1.5-1.6-0.9-0.9-2.2-0.7-1.0-1.3-1.7-1.2
Pavlov. Cond. lever-magazine prob. diff.2.83.67.2-2.00.81.81.71.92.02.02.72.41.81.51.4
Pavlov. Cond. response bias1.52.16.1-1.90.21.00.91.11.31.62.52.11.40.80.7
Conditioned reinforcement - actives0.30.30.80.5-0.2-0.4-0.4-0.5-0.6-0.4-0.8-0.7-0.9-0.4-0.4
Conditioned reinforcement - inactives0.40.41.3-1.1-0.20.50.40.70.80.21.11.0-0.4-0.00.1
Conditioned locomotion0.91.11.9-0.3-1.4-1.1-1.2-0.9-0.9-1.3-0.3-0.8-0.9-1.4-1.2
Intermittent access intake day 1-15 change0.30.30.5-0.20.50.70.70.70.70.60.50.60.40.60.6
Intermittent access intake escalation0.40.40.5-0.30.50.70.70.70.70.60.60.70.30.60.6
Intermittent access intake escalation 20.10.10.10.10.30.30.30.20.20.20.20.1-0.10.40.3
Intermitt. access day 1 inactive lever presses0.80.82.7-1.6-1.3-0.4-0.6-0.00.2-0.71.30.6-0.6-1.1-1.0
Intermitt. access day 15 inactive lever presses1.11.25.3-2.3-1.6-0.2-0.50.30.5-0.71.61.00.2-1.1-0.8
Intermitt. access escalation Index0.20.20.5-0.7-0.10.40.30.50.60.20.60.70.6-0.00.0
Intermittent access day 1 total infusions0.50.61.2-0.6-1.1-0.7-0.9-0.6-0.5-0.90.1-0.2-0.8-1.0-0.9
Intermittent access day 15 total infusions0.20.20.8-0.9-0.30.20.10.40.50.10.80.7-0.1-0.10.1
Intermittent access terminal intake (last 3 days)0.00.00.1-0.0-0.10.0-0.00.0-0.0-0.00.10.0-0.3-0.00.0
Intermittent access total infusions0.10.10.2-0.5-0.5-0.1-0.2-0.0-0.0-0.20.30.1-0.4-0.4-0.2
Intermittent access day 1 locomotion0.10.10.3-0.5-0.6-0.2-0.3-0.1-0.1-0.30.30.1-0.0-0.5-0.4
Intermittent access day 15 total locomotion0.00.10.1-0.3-0.3-0.1-0.2-0.1-0.0-0.20.30.1-0.3-0.3-0.3
Intermittent access total locomotion0.10.20.6-0.7-0.6-0.1-0.20.00.1-0.30.50.2-0.1-0.6-0.4
Intermittent access standard deviation0.30.30.9-0.9-1.0-0.3-0.5-0.1-0.0-0.50.80.3-0.1-0.6-0.4
Cocaine induced anxiety0.60.72.6-1.6-1.5-0.6-0.7-0.10.0-0.70.80.60.7-0.8-0.6
Post-drug Anxiety0.40.51.2-1.1-1.1-0.7-0.7-0.3-0.1-0.70.40.40.3-0.8-0.7
Baseline Anxiety0.60.61.91.11.40.80.90.40.30.9-0.5-0.0-0.11.00.7
Lifetime Intake0.40.41.4-1.2-1.1-0.3-0.50.00.1-0.50.90.4-0.1-0.7-0.5
Incentive Sensitization - Responses0.70.72.4-1.4-0.30.50.40.80.90.41.61.40.00.30.4
Incentive Sensitization - Breakpoint0.70.72.5-1.5-0.50.30.20.70.80.31.61.30.00.10.2
Progressive ratio test 1 active lever presses0.30.31.2-1.1-0.70.1-0.10.30.3-0.21.00.60.1-0.4-0.1
Progressive ratio test 1 breakpoint0.10.10.5-0.7-0.30.30.10.40.30.10.70.40.2-0.10.1
Progressive ratio test 1 inactive lever presses1.11.14.3-2.0-1.00.50.10.90.90.12.11.40.5-0.4-0.0
Progressive ratio test 2 active lever presses0.60.72.0-1.4-0.30.60.40.80.90.41.41.30.40.20.4
Progressive ratio test 2 breakpoint0.60.72.6-1.6-0.60.40.20.70.80.21.51.30.2-0.10.2
Progressive ratio test 2 inactive lever presses1.61.84.9-2.2-0.31.00.81.41.60.72.22.11.00.40.7
Total sessions with >9 infusions0.70.82.1-0.9-1.4-0.8-1.0-0.6-0.5-1.00.4-0.2-0.6-1.3-1.1
Short access day 1 total inactive lever presses1.51.73.3-1.1-1.8-1.4-1.4-1.0-0.8-1.50.2-0.4-1.2-1.8-1.8
Short access day 10 total inactive lever presses1.01.11.8-0.1-1.2-1.4-1.3-1.2-1.0-1.3-0.3-0.8-0.7-1.2-1.2
Short access day 1 total infusions1.11.22.9-1.1-1.7-1.0-1.2-0.7-0.6-1.20.5-0.2-0.8-1.6-1.4
Short access day 10 total infusions0.10.10.5-0.7-0.60.0-0.20.20.1-0.10.50.30.3-0.4-0.1
Short access total infusions0.91.03.3-1.6-1.8-0.7-1.0-0.3-0.2-0.91.10.30.2-1.3-0.9
Short access day 1 locomotion0.20.20.7-0.7-0.30.40.20.50.40.20.60.60.8-0.10.1
Short access day 10 total locomotion0.40.41.1-0.20.40.90.70.80.60.70.40.51.10.50.8
Short access total locomotion0.20.30.8-0.8-0.9-0.0-0.40.1-0.0-0.20.60.20.8-0.5-0.1
Compulsive drug intake0.70.71.1-0.20.90.81.00.80.90.90.41.00.61.10.9
One hour access (0.3 mA shock)0.60.71.3-0.20.70.90.90.90.80.90.60.90.91.01.2
One hour access (shock baseline)0.20.20.50.20.40.60.50.50.30.50.20.20.30.50.7
Number of responses in last shaping day2.12.23.9-1.60.31.51.21.71.71.31.92.01.60.91.1
Context. condit. distance diff. score5.77.08.61.0-2.3-2.9-2.9-2.9-2.9-2.9-2.0-2.8-2.6-2.9-2.9
Locomotion velocity, session 10.80.82.10.9-0.3-1.2-1.0-1.4-1.4-0.1-0.4-0.8-1.0-0.4-0.8
Locomotion distance, session 11.01.32.90.81.51.01.20.70.61.60.20.71.11.71.6
Locomotion velocity, session 20.50.61.60.5-0.6-1.0-1.0-1.2-1.3-0.2-0.2-0.6-0.2-0.6-0.6
Locomotion distance, session 22.43.54.6-1.21.31.91.92.02.02.01.82.12.01.81.9
Locomotion velocity, session 30.70.81.91.3-0.1-0.9-0.8-1.3-1.4-0.1-0.8-1.0-0.8-0.3-0.5
Locomotion distance, session 30.91.02.61.31.60.91.10.60.41.0-0.70.00.71.31.2
Stereotopy head waving bouts, day 31.01.32.30.0-1.1-1.3-1.3-1.4-1.3-0.8-0.1-0.8-1.4-1.3-1.5
Stereotopy head waving duration, day 34.45.48.00.6-2.2-2.8-2.7-2.8-2.8-1.9-0.8-1.9-2.7-2.4-2.8
Locomotion velocity, session 70.20.21.10.90.3-0.0-0.0-0.3-0.50.5-0.3-0.31.00.40.5
Locomotion distance, session 71.41.85.5-0.40.81.51.21.41.21.41.01.22.41.21.6
Stereotopy head waving bouts, day 75.86.611.31.7-1.7-3.1-2.8-3.4-3.3-1.9-1.7-2.5-3.1-2.1-2.7
Stereotopy head waving duration, day 74.15.18.41.7-1.3-2.6-2.4-2.9-2.9-1.7-1.8-2.4-2.7-1.7-2.2
Locomotion velocity, session 83.54.26.5-0.2-2.4-2.5-2.5-2.2-2.0-2.3-0.6-1.4-2.1-2.3-2.4
Locomotion distance, session 80.91.31.90.6-1.0-1.3-1.3-1.4-1.4-1.1-0.9-1.3-1.0-1.1-1.2
Degree of sensitization distance0.80.82.7-1.5-1.6-0.5-0.9-0.2-0.2-0.81.00.10.2-1.1-0.8
Degree of sensitization stereotypy4.24.67.51.7-1.1-2.5-2.2-2.7-2.7-1.6-1.8-2.3-2.6-1.6-2.1
Condit. Reinf. active minus inactive responses0.80.92.0-0.80.41.00.80.90.81.11.31.11.40.70.9
Condit. Reinf. active-inactive response ratio0.10.20.3-0.1-0.5-0.4-0.5-0.6-0.6-0.00.3-0.3-0.1-0.4-0.4
Condit. Reinf. active responses2.42.94.8-0.71.31.91.71.81.71.91.51.82.21.61.8
Condit. Reinf. inactive responses3.33.85.2-0.41.92.32.22.22.12.01.11.82.22.02.2
Incentive salience index mean1.92.24.6-1.00.71.51.31.41.31.71.71.72.21.31.6
Condit. Reinf. lever presses2.02.75.9-0.51.11.71.51.51.32.11.61.72.41.72.0
Time in familiar zone, hab. session 10.10.10.40.60.0-0.3-0.2-0.4-0.50.1-0.3-0.40.50.10.1
Time in novel zone, hab. session 11.81.84.50.2-1.0-1.3-1.2-1.1-0.9-1.8-1.2-1.3-2.1-1.5-1.6
Total zone transitions, hab. session 11.62.34.60.92.21.61.81.21.11.90.11.01.22.01.8
Total locomotion distance, hab. session 10.70.93.71.91.60.20.6-0.3-0.51.2-0.9-0.30.31.10.8
Locomotion velocity, hab. session 10.81.12.91.41.70.70.90.10.01.7-0.20.30.81.51.2
Time in familiar zone, hab. session 20.70.73.41.80.7-0.2-0.1-0.6-0.80.1-1.5-1.00.20.40.3
Time in novel zone, hab. session 20.80.82.3-1.5-1.1-0.5-0.5-0.10.2-1.00.70.2-1.4-1.1-1.1
Total zone transitions, hab. session 20.30.40.7-0.40.40.60.60.50.50.90.80.80.50.60.5
Total locomotion distance, hab. session 20.30.40.7-0.20.60.60.60.50.50.80.50.60.80.70.7
Locomotion velocity, hab. session 20.70.91.7-0.10.90.91.00.80.81.30.70.91.21.11.1
Novel to familiar place preference ratio5.96.214.20.6-1.7-2.5-2.3-2.3-2.0-3.0-2.0-2.6-3.8-2.7-3.0
Novelty place preference7.47.716.70.8-1.9-2.8-2.6-2.6-2.3-3.4-2.3-3.0-4.1-3.0-3.3
Time in novel zone, NPP test8.89.219.00.8-2.2-3.1-2.9-2.8-2.5-3.7-2.5-3.2-4.4-3.3-3.6
Total zone transitions, NPP test0.91.32.60.51.51.11.30.90.91.40.10.81.01.61.5
Total locomotion distance, NPP test0.50.61.10.10.90.70.90.60.71.00.30.71.01.01.0
Locomotion velocity, NPP test1.31.83.20.41.61.41.51.11.01.70.41.01.61.71.8
Pavlov. Cond. lever latency2.12.64.70.5-1.2-1.7-1.5-1.5-1.4-2.1-1.6-1.8-2.2-1.6-1.9
Pavlov. Cond. magazine entry latency2.02.63.9-1.01.11.91.72.01.91.41.21.71.91.41.8
Pavlov. Cond. change in total contacts2.83.04.8-1.40.81.81.62.01.91.51.82.12.21.41.8
Pavlov. Cond. index score1.82.23.7-1.20.61.61.31.71.61.41.61.81.91.11.5
Pavlov. Cond. latency score1.41.82.9-1.10.51.41.21.51.51.21.51.71.71.01.4
Pavlov. Cond. lever contacts2.93.46.1-0.71.32.01.81.91.82.11.61.92.51.82.2
Pavlov. Cond. magazine entry number1.72.13.40.9-0.9-1.7-1.5-1.8-1.7-1.2-1.1-1.5-1.8-1.2-1.7
Pavlov. Cond. intertrial magazine entries0.60.71.5-0.80.60.90.91.01.10.60.91.20.30.60.5
Pavlov. Cond. lever-magazine prob. diff.2.22.84.8-1.00.91.81.61.91.81.61.61.92.21.41.8
Pavlov. Cond. response bias2.93.66.4-1.01.22.11.92.12.01.91.62.02.51.72.1
Bone: apparent density0.30.51.0-0.30.60.70.70.70.70.80.61.00.50.60.5
Bone surface0.10.20.50.50.2-0.4-0.3-0.7-0.60.40.00.1-0.5-0.1-0.5
Bone volume0.00.10.20.30.1-0.3-0.2-0.4-0.40.30.00.0-0.2-0.1-0.3
Bone: connectivity density0.20.21.0-0.40.30.40.40.40.50.60.61.00.10.30.2
Bone: cortical apparent density0.70.91.3-0.30.91.21.11.11.01.20.80.90.91.01.0
Bone: cortical area1.32.03.2-0.0-1.7-1.8-1.8-1.6-1.5-1.5-0.4-0.9-1.1-1.6-1.7
Bone: cortical porosity0.40.50.80.4-0.6-0.8-0.8-0.8-0.9-0.5-0.3-0.5-0.8-0.6-0.7
Bone: cortical porosity1.21.31.80.3-1.1-1.4-1.4-1.4-1.4-1.0-0.5-0.9-1.3-1.2-1.3
Bone: cortical thickness0.40.62.6-1.6-0.90.0-0.10.50.7-0.41.10.90.6-0.4-0.1
Bone: cortical thickness0.40.41.9-1.4-0.9-0.1-0.20.40.6-0.90.50.20.1-0.7-0.3
Bone: cortical tissue density0.70.91.3-0.30.91.11.11.01.01.10.80.80.91.01.0
Bone: elastic displacement1.31.52.40.9-0.5-1.4-1.1-1.4-1.3-1.1-1.3-1.3-1.6-1.0-1.3
Bone: elastic work2.93.85.8-0.1-2.1-2.4-2.3-2.1-1.9-2.1-0.8-1.4-1.9-2.3-2.4
Bone: endosteal estimation2.65.710.12.0-1.2-2.7-2.4-3.2-3.2-1.5-1.9-2.5-2.6-2.0-2.5
Bone: endosteal perimeter3.46.912.92.6-1.2-2.9-2.7-3.5-3.6-1.7-2.4-2.9-2.6-2.0-2.5
Bone: final force0.81.33.3-1.4-1.8-1.1-1.2-0.7-0.5-1.10.90.2-0.6-1.5-1.4
Bone: final moment1.11.84.3-1.4-2.1-1.4-1.5-1.0-0.8-1.40.70.0-0.9-1.8-1.7
Bone: marrow area2.86.110.72.0-1.3-2.8-2.5-3.3-3.3-1.6-1.9-2.5-2.8-2.1-2.7
Bone: maximum diameter4.88.712.40.6-2.9-3.5-3.5-3.4-3.3-3.0-1.4-2.4-3.1-3.3-3.5
Bone: maximum force1.83.16.4-1.1-2.5-2.0-2.1-1.6-1.4-2.00.3-0.7-1.4-2.3-2.2
Bone: maximum moment2.34.07.7-1.2-2.8-2.3-2.4-1.8-1.6-2.30.1-0.8-1.7-2.6-2.5
Bone: minimum diameter0.91.73.71.1-0.9-1.7-1.5-1.9-1.9-0.7-0.8-1.0-0.9-1.0-1.3
Bone: periosteal estimation2.85.79.61.3-1.8-2.9-2.7-3.1-3.0-1.9-1.5-2.2-2.5-2.3-2.7
Bone: periosteal perimeter4.37.112.01.7-2.0-3.1-3.0-3.4-3.5-2.2-1.9-2.7-2.4-2.5-2.8
Bone: post-yield work0.20.30.9-0.9-1.0-0.5-0.6-0.2-0.1-0.60.50.20.0-0.7-0.5
Bone: stiffness0.81.23.0-0.9-1.7-1.2-1.4-0.9-0.8-1.20.4-0.3-0.5-1.4-1.3
Bone: tissue strength0.30.30.6-0.3-0.6-0.6-0.6-0.6-0.5-0.30.2-0.1-0.5-0.6-0.7
Bone: trabecular number0.10.10.70.90.60.20.2-0.1-0.30.4-0.50.0-0.10.30.1
Bone: trabecular spacing0.40.51.6-0.7-1.3-0.8-1.0-0.6-0.5-0.90.3-0.4-0.0-0.9-0.6
Bone: trabecular thickness0.10.20.40.10.40.40.40.30.20.70.30.40.60.50.3
Bone: trabecular tissue density0.71.02.4-1.20.61.11.11.41.60.61.01.20.20.70.7
Breakpoint value in progressive ratio session0.20.20.8-0.9-0.40.10.00.30.40.10.80.60.7-0.1-0.0
Distance traveled before self-admin1.41.53.9-1.4-0.11.10.81.31.20.91.51.52.00.60.9
Distance traveled after self-admin0.30.41.5-1.2-0.8-0.1-0.30.10.3-0.50.70.5-0.7-0.7-0.6
Delta time in closed arm before/after self-admin0.30.30.9-0.3-0.8-0.4-0.6-0.3-0.4-0.7-0.4-0.60.1-0.9-0.6
Delta time in open arm before/after self-admin0.20.10.60.80.5-0.10.1-0.2-0.30.3-0.2-0.2-0.00.60.4
Diff in mean of infusions in LGA sessions0.70.81.1-0.50.71.11.01.11.01.00.61.00.70.80.9
Extinction: sum of active levers before priming0.00.00.1-0.3-0.00.20.20.30.30.20.20.20.2-0.10.0
Active lever presses in extinction session 60.20.20.4-0.4-0.6-0.4-0.5-0.2-0.2-0.4-0.1-0.10.4-0.6-0.5
Delta distance traveled before/after self-admin2.93.18.30.7-1.0-1.8-1.6-1.8-1.7-1.9-1.5-1.8-2.9-1.6-1.9
Delta ambulatory time before/after self-admin4.04.311.40.5-1.4-2.2-2.0-2.1-1.9-2.4-1.6-1.9-3.4-2.0-2.4
Time in closed arm before self-admin3.74.35.6-0.52.02.32.42.22.22.31.52.31.72.32.3
Time in closed arm after self-admin0.10.10.40.3-0.3-0.1-0.3-0.2-0.3-0.3-0.6-0.50.2-0.2-0.0
Time in open arm before self-admin0.30.31.31.10.5-0.10.0-0.3-0.4-0.1-1.1-0.9-0.2-0.0-0.0
Time in open arm after self-admin0.30.41.61.31.00.20.4-0.1-0.20.5-0.5-0.40.30.80.5
Sum of active levers in priming session hrs 5-60.10.10.6-0.20.10.20.20.20.20.40.30.30.80.10.1
Time to tail flick, vehicle, before self-admin0.70.71.80.5-0.3-0.9-0.7-0.9-0.8-0.8-0.9-0.8-1.3-0.7-0.8
Time to tail flick, vehicle, after self-admin0.80.93.61.91.3-0.00.3-0.4-0.50.2-1.7-1.0-0.60.70.3
Time to tail flick, test, before self-admin0.70.73.01.40.3-0.5-0.4-0.8-0.9-0.4-1.7-1.2-0.10.00.0
Time to tail flick, test, after self-admin1.31.32.60.61.61.41.41.11.01.30.10.71.01.31.3
Delta time to tail flick, vehicle, before/after SA0.20.10.3-0.30.30.40.40.50.50.30.20.40.50.30.3
Delta time to tail flick, test, before/after SA1.91.72.7-0.31.51.61.61.51.51.51.11.30.41.21.1
Ambulatory time before self-admin0.90.92.1-1.2-0.10.80.61.01.00.81.51.31.30.50.8
Ambulatory time after self-admin0.20.21.2-0.7-0.10.00.10.20.3-0.30.10.3-1.1-0.3-0.4
Total heroin consumption0.10.10.6-0.8-0.6-0.3-0.3-0.00.1-0.20.40.20.2-0.5-0.4
Area under the delay curve0.70.71.3-0.10.81.11.01.00.91.00.40.80.90.80.9
Delay disc. indifference point, 0s delay0.30.30.6-0.1-0.8-0.5-0.7-0.5-0.6-0.6-0.1-0.40.3-0.7-0.5
Delay disc. indifference point, 16s delay1.81.82.8-0.21.41.71.61.51.41.60.91.31.11.41.4
Delay disc. indifference point, 2s delay0.20.20.50.10.30.60.40.50.30.5-0.00.20.70.30.5
Delay disc. indifference point, 24s delay0.20.20.50.70.70.30.30.0-0.00.3-0.6-0.2-0.20.40.2
Delay disc. indifference point, 4s delay0.40.41.4-1.2-0.30.50.30.70.70.20.90.90.3-0.3-0.1
Delay disc. indifference point, 8s delay1.81.82.60.01.31.61.51.51.31.60.61.11.61.41.6
Delay discount exponential model param0.70.71.20.0-0.8-1.1-1.0-1.0-0.8-1.0-0.3-0.7-0.9-0.8-0.9
Delay discount hyperbolic model param0.50.50.90.1-0.6-0.9-0.8-0.8-0.7-0.8-0.3-0.6-0.8-0.6-0.7
Fecal boli incidents, locomotor time 10.30.30.5-0.10.50.60.60.60.60.70.20.50.70.50.5
Change in fecal boli incidents, locomotor task1.11.12.00.9-0.4-1.1-0.9-1.2-1.2-1.0-1.2-1.2-1.4-0.6-0.8
Time >=10cm from walls, locomotor time 10.00.00.1-0.0-0.00.0-0.0-0.1-0.20.10.20.00.30.1-0.0
Bouts of movement, locomotor time 10.00.00.20.00.10.30.20.20.10.30.10.20.40.10.3
Total resting periods, locomotor time 10.40.51.2-0.40.30.80.60.80.70.70.70.81.10.50.7
Rest time, locomotor task time 10.60.72.1-1.0-0.20.70.40.90.80.51.10.91.50.20.6
Distance moved, locomotor task time 11.01.11.70.8-0.5-1.0-1.0-1.3-1.3-0.9-1.1-1.2-1.2-0.8-1.1
Vertical activity count, locomotor time 10.10.10.5-0.0-0.2-0.4-0.3-0.4-0.3-0.3-0.1-0.1-0.7-0.3-0.5
Time >=10cm from walls, locomotor time 20.10.20.40.50.60.40.40.20.10.5-0.00.10.50.50.4
Bouts of movement, locomotor time 20.30.30.9-0.9-0.30.50.20.60.50.20.80.70.60.10.4
Total resting periods, locomotor time 20.40.41.2-1.1-0.30.50.30.70.70.20.90.80.50.10.4
Rest time, locomotor task time 20.30.30.5-0.50.30.60.60.70.70.50.50.60.40.50.6
Distance moved, locomotor task time 20.80.91.60.9-0.7-1.1-1.1-1.2-1.3-0.9-0.9-1.2-0.5-0.7-0.7
Vertical activity count, locomotor time 20.60.61.00.4-0.7-1.0-1.0-1.0-1.0-0.9-0.5-0.8-0.7-0.6-0.7
Weight adjusted by age0.80.92.21.20.2-0.7-0.5-0.9-0.9-0.6-1.5-1.3-1.2-0.4-0.6
Seeking ratio, delayed vs. immediate footshock4.65.37.6-0.91.82.42.42.42.42.52.02.52.82.42.4
Locomotion in novel chamber1.01.35.32.31.1-0.3-0.0-0.8-0.9-0.0-1.9-1.7-0.30.60.3
Locomotion in novel chamber post-restriction1.21.52.70.71.41.21.30.90.71.60.30.81.61.61.5
Progressive ratio0.10.20.6-0.8-0.10.30.20.40.50.20.60.60.10.10.1
Food seeking constrained by brief footshock0.91.11.6-0.0-1.3-1.2-1.3-1.1-1.2-1.1-0.4-0.9-1.1-1.2-1.2
Seeking ratio, punishment vs. effort0.30.30.50.2-0.6-0.6-0.7-0.6-0.7-0.6-0.3-0.6-0.3-0.6-0.6
Run reversals in cocaine runway, females0.80.82.91.71.50.60.7-0.0-0.30.9-1.1-0.6-0.11.00.7
Run reversals in cocaine runway, males1.71.63.60.8-0.6-1.3-1.2-1.4-1.3-1.2-1.5-1.5-1.9-1.0-1.1
Latency to leave start box in cocaine runway0.10.10.10.0-0.3-0.3-0.3-0.2-0.3-0.3-0.2-0.30.3-0.3-0.1
Latency to leave start box in cocaine runway, F0.20.20.40.30.60.50.50.40.30.6-0.00.10.40.50.5
Latency to leave start box in cocaine runway, M0.80.82.1-0.7-1.4-0.9-1.1-0.6-0.6-1.20.1-0.40.2-1.2-0.9
Cd content in liver2.22.44.50.7-1.1-1.6-1.4-1.3-1.2-2.1-2.1-1.8-1.8-1.5-1.4
Co content in liver0.60.72.0-0.5-1.0-0.7-0.7-0.3-0.1-1.4-0.5-0.5-1.3-1.1-1.0
Cu content in liver3.84.57.2-0.22.32.42.42.12.02.71.42.12.22.52.2
Fe content in liver0.50.61.50.4-0.4-0.8-0.8-1.0-1.0-0.3-0.3-0.6-1.2-0.8-1.1
K content in liver0.70.72.0-1.10.20.70.60.70.80.91.41.11.00.40.4
Mg content in liver2.22.35.5-1.60.41.31.21.31.41.72.42.11.81.21.1
Mn content in liver0.30.30.90.9-0.0-0.4-0.4-0.7-0.8-0.1-0.8-0.70.0-0.3-0.3
Na content in liver2.42.63.5-0.31.71.81.91.71.71.70.91.51.71.81.7
Rb content in liver0.10.20.7-0.7-0.4-0.0-0.10.00.10.20.80.7-0.0-0.1-0.2
Se content in liver0.40.51.20.71.10.70.80.30.21.1-0.00.40.80.90.7
Sr content in liver1.01.02.10.31.11.11.11.21.20.4-0.30.40.91.21.5
Zn content in liver0.50.51.20.41.10.70.90.60.61.00.20.50.41.10.8