Hub : Genes

Scp2d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000009461 0.32 0.11 5.6e-11 0.23 0.18 0.22 0.23 2.3e-12 7.6e-10 3.2e-12 2.1e-12
2 Brain alternative polyA ENSRNOT00000012524 0.03 0.02 1.2e-03 0.04 0.03 0.03 0.04 2.7e-04 1.1e-03 4.0e-04 2.9e-04
3 Brain gene expression ENSRNOG00000009461 0.2 0.07 0.0e+00 0.23 0.23 0.24 0.25 1.5e-21 9.1e-21 5.2e-22 7.6e-23
4 IL gene expression ENSRNOG00000009461 0.45 0.2 5.1e-04 0.07 0.05 0.08 0.08 7.4e-03 2.4e-02 5.2e-03 5.2e-03
5 LHb gene expression ENSRNOG00000009461 0.49 0.15 7.5e-08 0.36 0.18 0.3 -0.01 1.5e-09 5.1e-05 8.3e-08 8.5e-01
6 NAcc gene expression ENSRNOG00000009461 0.21 0.08 1.9e-14 0.23 0.17 0.21 0.22 2.4e-17 6.7e-13 1.1e-15 1.6e-16
7 OFC gene expression ENSRNOG00000009461 0.55 0.16 1.0e-05 0.11 0.15 0.15 0.14 1.2e-03 2.5e-04 2.5e-04 4.4e-04
8 PL gene expression ENSRNOG00000009461 0.27 0.09 0.0e+00 0.25 0.14 0.25 0.21 7.3e-19 4.6e-11 3.9e-19 8.2e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail4.815.720.8-4.2-4.3-3.4-2.5-4.1-4.3-4.6-4.0
BMI without tail3.98.211.4-3.1-2.5-3.4-2.1-2.4-3.3-2.9-3.0
Body weight3.715.722.4-4.3-4.1-3.8-1.7-3.8-4.7-4.6-3.9
Epididymis fat weight2.66.18.2-2.6-2.5-2.6-1.2-2.2-2.9-2.9-2.5
Glucose0.20.41.0-0.5-0.3-0.8-0.1-0.1-0.7-1.0-0.5
Heart weight1.21.72.9-1.2-1.0-1.3-0.7-1.0-1.7-1.7-1.4
Left kidney weight0.82.43.9-1.6-1.4-1.8-0.7-1.4-2.0-1.5-1.6
Right kidney weight0.61.83.1-1.3-1.2-1.5-0.2-1.2-1.8-1.6-1.5
Tail length0.10.20.7-0.30.3-0.90.50.5-0.4-0.1-0.2
Length with tail0.31.12.4-1.3-0.8-1.5-0.1-0.6-1.6-0.9-0.9
Length without tail0.51.11.9-1.1-1.2-0.8-0.1-1.2-1.4-1.0-0.9
Liver weight, left0.10.10.60.10.10.20.50.10.10.80.5
Liver weight, right0.40.72.20.40.30.61.30.40.61.50.9
Parametrial fat weight10.720.925.0-5.0-4.5-4.9-3.4-4.3-4.8-4.8-4.7
Retroperitoneal fat weight7.725.433.6-5.4-5.1-5.2-3.1-4.9-5.4-5.8-5.0
Intraocular pressure4.05.78.52.62.92.22.02.92.31.52.4
Extensor digitorum longus weight0.00.10.6-0.4-0.1-0.80.3-0.1-0.50.1-0.2
Soleus weight0.00.10.50.20.3-0.20.70.30.00.50.4
Tibialis anterior weight0.31.22.3-1.3-1.1-1.5-0.3-0.9-1.3-0.8-1.0
Tibia length1.43.95.7-2.4-2.2-2.2-0.6-2.1-2.0-1.6-2.1
Number of licking bursts0.30.30.80.60.30.90.50.50.60.40.5
Food consumed during 24 hour testing period0.40.52.10.60.40.41.40.50.50.70.6
Times rat made contact with spout3.03.45.0-1.9-1.6-2.2-1.4-1.5-1.8-2.2-1.9
Mean time between licks in bursts0.10.10.30.30.40.50.10.30.10.40.4
Mean num. licks in bursts1.41.73.6-1.4-1.0-1.9-0.9-1.1-1.3-1.4-1.3
Std. dev. time between licks in bursts1.11.31.61.21.21.30.61.11.21.21.2
Water consumed over 24 hours0.10.10.40.10.4-0.60.60.4-0.2-0.1-0.1
Indifference point 0 sec0.60.91.51.01.21.01.21.20.20.30.9
Indifference point AUC0.10.20.50.30.30.30.20.20.70.50.3
Indifference point function ln k0.20.30.60.60.60.50.50.70.10.30.5
Indifference point function log k0.20.30.60.60.60.50.50.70.10.30.5
Delay discounting total patch changes 0 sec0.60.91.61.01.31.01.11.30.30.50.9
Delay discounting total patch changes 12 sec0.10.10.3-0.2-0.30.20.5-0.2-0.0-0.3-0.0
Delay discounting total patch changes 18 sec1.01.31.71.11.21.31.31.30.80.81.2
Delay discounting total patch changes 24 sec0.20.30.50.60.70.50.60.50.30.60.5
Delay discounting total patch changes 6 sec0.71.01.51.11.01.21.21.00.70.61.0
Delay discounting time to switch 0 sec0.91.42.6-1.4-1.6-1.0-0.5-1.4-1.2-0.9-1.2
Delay discounting water rate 0 sec1.52.43.01.71.71.71.11.61.51.51.6
Delay discounting water rate 12 sec3.55.26.82.42.22.61.42.02.62.22.5
Delay discounting water rate 18 sec12.416.518.74.34.23.93.64.24.23.94.1
Delay discounting water rate 24 sec4.66.48.72.72.92.52.12.92.41.82.5
Delay discounting water rate 6 sec4.26.17.32.72.72.71.72.42.52.42.6
Locomotor activity0.30.40.8-0.6-0.6-0.8-0.4-0.5-0.7-0.7-0.9
Locomotor testing distance0.00.00.1-0.00.0-0.3-0.3-0.1-0.1-0.1-0.3
Locomotor testing rearing0.40.71.2-0.6-0.5-1.1-0.6-0.5-0.9-0.9-1.0
Light reinforcement 10.71.22.31.11.40.50.91.50.81.11.1
Light reinforcement 20.30.41.3-0.20.6-1.0-1.20.3-0.70.1-0.4
Reaction time number correct1.72.54.31.82.11.61.52.10.91.01.3
Reaction time mean minus median2.12.84.0-1.8-1.7-2.0-0.4-1.4-1.7-1.9-1.8
Reaction time mean minus median AUC1.62.13.5-1.5-1.3-1.9-0.3-1.0-1.5-1.8-1.5
Reaction time num false alarms1.41.93.31.41.31.50.71.21.41.81.4
Reaction time num false alarms AUC1.11.62.21.41.21.50.51.21.31.51.2
Reaction time trials correct on left1.72.54.31.82.11.61.52.10.91.01.3
Reaction time trials on left1.62.34.21.72.01.51.42.10.80.91.2
Reaction time mean2.83.97.3-2.0-1.8-2.4-0.7-1.5-1.9-2.7-2.0
Reaction time mean AUC2.93.86.6-2.0-1.8-2.4-1.0-1.5-1.9-2.6-2.0
Median of all reaction times2.33.26.4-1.8-1.6-2.2-0.8-1.3-1.7-2.5-1.8
Reaction time omissions0.60.91.8-0.9-0.7-1.1-0.7-0.3-1.2-1.3-0.8
Reaction time false alarm rate0.20.31.00.50.20.6-0.20.20.81.00.6
Reaction time premature initiation rate0.20.30.50.60.60.50.70.60.70.30.5
Reaction time premature initiations1.41.92.71.51.71.41.61.61.20.91.2
Std. dev. reaction times2.12.85.0-1.8-1.6-2.1-0.5-1.3-1.6-2.2-1.7
Reaction time trials completed1.62.34.21.72.01.51.42.10.80.91.2
Reaction time trials AUC1.92.85.11.92.21.61.72.30.81.01.4
Social response proportion6.06.59.0-2.7-2.4-2.7-2.2-2.2-2.5-3.0-2.7
Social responses0.10.10.4-0.2-0.3-0.10.20.1-0.2-0.6-0.3
Social time1.62.02.5-1.5-1.5-1.2-1.4-1.4-1.4-1.6-1.5
Conditioned locomotion0.10.20.50.30.70.40.00.70.0-0.00.3
Cocaine response after cond. corrected3.43.85.02.12.11.62.02.21.91.62.0
Cocaine response after cond. not corrected5.86.58.02.72.72.22.22.82.52.32.7
Cocaine response before conditioning0.30.30.60.60.50.5-0.10.40.50.80.7
Saline control response0.60.82.5-0.7-0.1-1.6-0.1-0.0-1.3-0.9-0.8
Condit. Reinf. active minus inactive responses1.11.32.7-1.3-0.8-1.6-0.9-0.9-1.5-0.8-1.2
Condit. Reinf. active-inactive response ratio1.01.12.6-1.0-0.7-1.6-0.9-0.6-1.2-0.7-1.1
Condit. Reinf. active responses1.01.41.8-1.4-1.3-1.1-1.0-1.3-1.3-0.9-1.2
Condit. Reinf. inactive responses0.50.61.4-0.8-1.10.2-0.6-1.2-0.5-0.5-0.5
Condit. Reinf. lever presses3.34.66.5-2.3-1.9-2.6-1.6-1.9-2.5-2.1-2.2
Condit. Reinf. lever reinforcers received1.62.32.9-1.6-1.5-1.6-1.3-1.6-1.7-1.1-1.5
Pavlov. Cond. lever latency2.53.56.31.91.81.90.91.62.02.51.9
Pavlov. Cond. magazine entry latency1.11.32.9-0.9-0.4-1.6-0.4-0.4-1.5-1.7-1.0
Pavlov. Cond. change in total contacts4.86.78.1-2.7-2.6-2.8-1.6-2.5-2.7-2.8-2.6
Pavlov. Cond. index score3.54.68.6-2.1-1.9-2.4-1.2-1.7-2.4-2.9-2.2
Pavlov. Cond. latency score2.63.36.8-1.8-1.6-2.0-1.0-1.4-1.9-2.6-1.8
Pavlov. Cond. lever contacts2.13.05.0-1.8-1.6-1.9-0.8-1.5-1.9-2.2-1.7
Pavlov. Cond. magazine entry number2.02.54.31.61.32.10.71.11.82.01.6
Pavlov. Cond. intertrial magazine entries1.01.22.11.10.81.40.20.91.31.51.2
Pavlov. Cond. lever-magazine prob. diff.4.15.49.0-2.4-2.2-2.5-1.4-2.0-2.5-3.0-2.3
Pavlov. Cond. response bias2.43.35.5-1.8-1.5-2.1-0.9-1.4-2.1-2.3-1.8
Conditioned reinforcement - actives1.51.52.41.11.30.21.51.51.01.41.1
Conditioned reinforcement - inactives2.73.14.11.81.91.52.02.01.41.81.6
Conditioned locomotion0.10.10.40.10.1-0.4-0.40.20.30.60.1
Intermittent access intake day 1-15 change0.60.51.3-0.6-0.4-1.1-0.2-0.6-1.2-0.6-0.7
Intermittent access intake escalation0.20.20.6-0.2-0.1-0.70.0-0.3-0.8-0.2-0.4
Intermittent access intake escalation 20.30.30.9-0.4-0.3-0.7-0.1-0.3-0.9-0.3-0.5
Intermitt. access day 1 inactive lever presses0.40.41.00.80.40.61.00.30.60.40.7
Intermitt. access day 15 inactive lever presses0.20.20.80.0-0.0-0.20.90.3-0.4-0.7-0.0
Intermitt. access escalation Index4.84.36.8-2.1-1.4-2.3-2.6-1.7-2.4-1.9-2.0
Intermittent access day 1 total infusions0.10.20.3-0.5-0.5-0.6-0.3-0.6-0.2-0.1-0.3
Intermittent access day 15 total infusions0.40.40.8-0.6-0.6-0.9-0.2-0.7-0.8-0.6-0.6
Intermittent access terminal intake (last 3 days)0.70.81.2-0.9-0.8-1.1-0.6-1.1-0.9-0.8-0.8
Intermittent access total infusions0.80.91.6-0.9-0.8-1.3-0.8-0.9-1.0-0.7-0.9
Intermittent access day 1 locomotion0.50.51.0-0.7-0.8-0.7-1.0-1.0-0.1-0.1-0.5
Intermittent access day 15 total locomotion0.20.20.6-0.3-0.2-0.7-0.8-0.2-0.3-0.3-0.3
Intermittent access total locomotion0.10.20.5-0.3-0.4-0.5-0.7-0.50.10.1-0.2
Intermittent access standard deviation0.10.20.50.50.20.10.50.5-0.00.70.2
Cocaine induced anxiety0.10.10.50.30.50.10.70.30.20.40.2
Post-drug Anxiety0.30.40.6-0.6-0.3-0.70.7-0.3-0.6-0.8-0.6
Baseline Anxiety1.51.63.2-1.3-1.2-1.2-0.7-0.9-1.4-1.8-1.2
Lifetime Intake0.40.41.0-0.6-0.4-1.0-0.6-0.5-0.8-0.6-0.7
Incentive Sensitization - Responses0.20.20.80.10.4-0.3-0.40.2-0.00.90.4
Incentive Sensitization - Breakpoint0.20.20.5-0.10.2-0.5-0.60.0-0.30.70.2
Progressive ratio test 1 active lever presses0.20.30.5-0.6-0.5-0.7-0.1-0.7-0.4-0.2-0.5
Progressive ratio test 1 breakpoint0.40.40.9-0.8-0.7-0.7-0.1-1.0-0.5-0.4-0.6
Progressive ratio test 1 inactive lever presses0.40.40.80.70.90.10.90.90.20.20.6
Progressive ratio test 2 active lever presses0.10.10.50.10.1-0.10.30.10.30.70.4
Progressive ratio test 2 breakpoint0.10.10.4-0.1-0.1-0.20.3-0.20.10.60.2
Progressive ratio test 2 inactive lever presses0.10.20.60.00.5-0.8-0.20.5-0.40.20.1
Total sessions with >9 infusions0.80.91.7-0.8-0.7-1.3-0.8-0.7-1.0-1.1-1.0
Short access day 1 total inactive lever presses1.01.12.41.21.50.21.01.60.30.90.8
Short access day 10 total inactive lever presses0.20.20.8-0.10.0-0.4-0.00.1-0.6-0.9-0.4
Short access day 1 total infusions0.50.51.20.81.10.00.61.00.40.60.5
Short access day 10 total infusions0.20.20.7-0.5-0.4-0.8-0.2-0.2-0.4-0.6-0.5
Short access total infusions0.60.61.3-0.7-0.5-1.2-0.7-0.5-0.8-0.9-0.9
Short access day 1 locomotion0.80.81.5-0.9-0.7-1.2-0.7-0.6-0.9-1.0-1.1
Short access day 10 total locomotion1.41.52.51.21.10.71.31.21.61.41.2
Short access total locomotion0.40.40.8-0.6-0.6-0.9-0.6-0.7-0.2-0.2-0.7
Compulsive drug intake0.50.51.10.50.80.20.50.90.41.10.6
One hour access (0.3 mA shock)0.10.10.50.20.3-0.0-0.00.20.20.70.2
One hour access (shock baseline)0.10.20.4-0.3-0.6-0.0-0.3-0.5-0.3-0.4-0.3
Number of responses in last shaping day1.71.73.41.41.30.91.81.71.10.71.1
Context. condit. distance diff. score0.00.00.1-0.10.1-0.00.30.1-0.20.10.2
Locomotion velocity, session 10.20.30.80.10.6-0.6-0.90.20.00.6-0.1
Locomotion distance, session 13.24.25.72.22.11.71.62.02.32.42.0
Locomotion velocity, session 20.91.13.11.00.80.60.50.61.51.81.0
Locomotion distance, session 23.95.59.12.52.81.41.82.52.23.02.2
Locomotion velocity, session 32.12.43.11.71.61.70.61.51.71.81.6
Locomotion distance, session 31.01.11.71.10.91.30.30.91.31.21.2
Stereotopy head waving bouts, day 30.20.30.9-0.3-0.2-0.4-0.3-0.4-0.6-1.0-0.7
Stereotopy head waving duration, day 30.40.40.9-0.5-0.3-0.6-0.6-0.6-0.8-1.0-0.8
Locomotion velocity, session 72.22.42.61.51.61.31.51.61.61.61.6
Locomotion distance, session 71.11.42.11.21.41.21.21.41.10.51.3
Stereotopy head waving bouts, day 70.10.10.1-0.3-0.2-0.40.0-0.2-0.3-0.2-0.3
Stereotopy head waving duration, day 70.00.00.10.00.0-0.2-0.2-0.00.10.3-0.0
Locomotion velocity, session 80.30.30.80.40.8-0.10.50.70.40.90.4
Locomotion distance, session 82.74.05.92.02.21.51.82.11.82.42.1
Degree of sensitization distance0.20.20.50.10.4-0.10.70.4-0.1-0.70.0
Degree of sensitization stereotypy0.20.20.4-0.6-0.5-0.6-0.2-0.4-0.5-0.5-0.5
Condit. Reinf. active minus inactive responses0.40.40.60.70.70.50.80.80.50.60.7
Condit. Reinf. active-inactive response ratio0.50.50.90.80.80.70.70.90.70.40.7
Condit. Reinf. active responses0.50.60.90.80.70.50.80.80.60.90.8
Condit. Reinf. inactive responses0.00.00.1-0.1-0.1-0.10.3-0.1-0.10.4-0.1
Incentive salience index mean1.01.12.61.00.70.80.90.81.21.61.1
Condit. Reinf. lever presses0.60.92.60.60.10.80.70.31.31.60.9
Time in familiar zone, hab. session 10.10.10.2-0.1-0.5-0.1-0.4-0.40.2-0.3-0.1
Time in novel zone, hab. session 10.20.20.6-0.40.0-0.6-0.30.0-0.7-0.8-0.6
Total zone transitions, hab. session 10.60.92.21.00.90.50.40.81.11.50.9
Total locomotion distance, hab. session 11.11.63.31.31.30.91.11.01.41.81.1
Locomotion velocity, hab. session 11.42.14.61.51.41.21.11.11.62.11.4
Time in familiar zone, hab. session 20.10.10.5-0.10.0-0.7-0.3-0.1-0.3-0.1-0.4
Time in novel zone, hab. session 20.10.10.4-0.3-0.2-0.1-0.1-0.1-0.3-0.7-0.2
Total zone transitions, hab. session 20.20.20.50.40.7-0.40.20.50.00.70.3
Total locomotion distance, hab. session 20.40.61.50.71.2-0.50.50.90.01.10.5
Locomotion velocity, hab. session 20.70.92.40.91.4-0.20.61.00.41.50.8
Novel to familiar place preference ratio0.20.20.40.40.30.60.50.50.3-0.10.4
Novelty place preference0.10.10.40.40.20.60.20.40.3-0.10.4
Time in novel zone, NPP test0.00.00.10.10.10.30.10.3-0.0-0.40.1
Total zone transitions, NPP test0.91.33.61.01.10.40.91.01.01.91.2
Total locomotion distance, NPP test1.52.14.01.41.70.51.31.51.02.01.4
Locomotion velocity, NPP test1.92.75.31.61.90.81.51.71.32.31.7
Pavlov. Cond. lever latency2.53.27.9-1.5-0.8-1.8-1.4-0.9-2.2-2.8-2.0
Pavlov. Cond. magazine entry latency0.20.20.7-0.4-0.90.10.1-0.8-0.10.3-0.3
Pavlov. Cond. change in total contacts2.82.95.11.50.82.31.60.82.22.11.8
Pavlov. Cond. index score0.70.93.10.5-0.31.00.8-0.21.21.80.8
Pavlov. Cond. latency score1.21.65.00.90.21.41.00.21.62.21.3
Pavlov. Cond. lever contacts1.61.85.20.90.41.21.30.51.82.31.4
Pavlov. Cond. magazine entry number0.20.30.80.30.9-0.3-0.70.8-0.1-0.40.1
Pavlov. Cond. intertrial magazine entries0.70.82.40.91.50.20.51.40.00.90.7
Pavlov. Cond. lever-magazine prob. diff.0.60.82.80.3-0.50.90.7-0.41.11.70.7
Pavlov. Cond. response bias0.50.71.60.3-0.30.91.1-0.20.91.30.7
Bone: apparent density0.20.30.70.40.40.40.20.60.50.50.8
Bone surface0.40.71.4-1.0-0.7-1.2-0.6-0.7-0.9-0.5-0.7
Bone volume0.00.00.1-0.10.2-0.30.10.3-0.20.10.3
Bone: connectivity density0.00.00.10.00.00.1-0.20.00.20.20.3
Bone: cortical apparent density0.10.20.6-0.2-0.70.6-0.2-0.80.20.10.0
Bone: cortical area0.20.30.6-0.6-0.8-0.20.2-0.8-0.40.4-0.2
Bone: cortical porosity1.41.52.0-1.2-1.0-1.3-1.3-1.3-1.3-0.9-1.4
Bone: cortical porosity1.51.72.2-1.3-1.2-1.2-1.1-1.4-1.5-1.1-1.5
Bone: cortical thickness0.71.23.2-1.2-1.6-0.4-1.0-1.8-0.70.2-0.9
Bone: cortical thickness0.91.03.10.90.51.80.60.51.30.81.1
Bone: cortical tissue density0.10.20.5-0.2-0.70.5-0.1-0.70.1-0.0-0.0
Bone: elastic displacement1.01.11.7-1.1-1.1-0.8-1.3-1.3-0.6-1.0-1.1
Bone: elastic work2.53.24.3-2.0-2.1-1.7-1.5-2.0-1.6-1.6-1.8
Bone: endosteal estimation0.30.62.3-0.50.1-1.50.70.4-1.0-0.7-0.4
Bone: endosteal perimeter0.20.41.20.10.7-0.61.10.8-0.40.00.2
Bone: final force0.10.10.3-0.5-0.6-0.20.3-0.4-0.50.2-0.2
Bone: final moment0.10.10.2-0.4-0.5-0.20.2-0.4-0.40.3-0.1
Bone: marrow area0.30.62.4-0.50.1-1.60.60.4-1.0-0.7-0.4
Bone: maximum diameter0.10.10.6-0.20.0-0.40.80.2-0.4-0.30.0
Bone: maximum force0.10.20.7-0.2-0.3-0.10.8-0.2-0.40.4-0.0
Bone: maximum moment0.10.10.5-0.2-0.3-0.10.7-0.2-0.30.60.1
Bone: minimum diameter0.40.71.3-1.1-0.9-1.1-0.3-0.8-1.1-0.1-0.7
Bone: periosteal estimation0.20.41.3-0.7-0.4-1.20.5-0.2-0.9-0.2-0.4
Bone: periosteal perimeter0.10.20.5-0.4-0.0-0.70.3-0.0-0.60.2-0.2
Bone: post-yield work0.30.41.40.50.40.01.20.50.20.80.4
Bone: stiffness0.10.21.10.10.10.31.00.2-0.30.60.3
Bone: tissue strength0.80.81.8-1.0-0.9-1.3-0.8-0.8-0.8-0.4-0.9
Bone: trabecular number0.20.30.70.40.30.4-0.10.40.60.80.7
Bone: trabecular spacing0.91.12.2-1.1-1.3-0.50.1-1.2-0.9-1.5-1.1
Bone: trabecular thickness0.10.10.20.20.20.2-0.00.30.30.40.5
Bone: trabecular tissue density0.40.61.3-0.8-1.1-0.5-0.7-1.2-0.6-0.2-0.6
Breakpoint value in progressive ratio session1.01.11.7-1.1-0.4-1.3-1.2-0.6-0.9-1.1-1.2
Distance traveled before self-admin0.10.10.5-0.4-0.7-0.10.2-0.2-0.1-0.0-0.3
Distance traveled after self-admin0.70.82.0-0.9-1.1-0.1-1.4-1.0-0.6-0.3-0.8
Delta time in closed arm before/after self-admin0.10.10.10.30.30.30.20.30.20.10.3
Delta time in open arm before/after self-admin1.51.41.9-1.2-1.1-1.2-1.4-0.9-1.1-1.4-1.2
Diff in mean of infusions in LGA sessions0.30.30.70.50.40.60.70.40.80.60.5
Extinction: sum of active levers before priming0.10.10.40.20.3-0.20.50.60.30.30.2
Active lever presses in extinction session 61.31.32.2-1.3-0.8-1.5-0.9-0.7-1.5-1.0-1.2
Delta distance traveled before/after self-admin0.80.91.9-0.8-0.80.0-1.3-1.4-0.8-0.7-0.8
Delta ambulatory time before/after self-admin0.50.51.9-0.5-0.40.1-1.4-0.8-0.5-0.6-0.5
Time in closed arm before self-admin0.20.20.60.30.40.40.80.40.20.10.4
Time in closed arm after self-admin0.60.61.70.70.60.51.30.80.50.70.7
Time in open arm before self-admin1.41.52.2-1.1-1.1-1.2-1.4-1.5-1.1-1.0-1.3
Time in open arm after self-admin5.05.58.7-2.4-2.2-2.2-3.0-2.4-2.0-1.9-2.4
Sum of active levers in priming session hrs 5-61.01.01.80.91.30.71.21.10.90.70.8
Time to tail flick, vehicle, before self-admin1.71.74.0-0.9-0.4-1.6-1.1-0.8-1.6-2.0-1.3
Time to tail flick, vehicle, after self-admin2.62.75.71.40.92.02.41.51.71.11.7
Time to tail flick, test, before self-admin0.50.51.00.80.90.41.00.60.80.50.7
Time to tail flick, test, after self-admin1.21.22.61.11.30.71.41.60.60.41.1
Delta time to tail flick, vehicle, before/after SA6.46.29.22.31.73.02.82.22.52.52.7
Delta time to tail flick, test, before/after SA0.20.20.70.40.50.10.20.80.00.30.4
Ambulatory time before self-admin0.20.20.4-0.6-0.7-0.20.1-0.4-0.4-0.3-0.4
Ambulatory time after self-admin0.40.41.2-0.7-0.90.3-1.1-0.8-0.4-0.2-0.5
Total heroin consumption0.30.31.00.21.0-0.7-0.51.00.0-0.10.0
Area under the delay curve0.91.02.01.00.81.20.40.81.41.01.0
Delay disc. indifference point, 0s delay0.10.10.3-0.5-0.4-0.5-0.4-0.4-0.00.0-0.4
Delay disc. indifference point, 16s delay1.91.92.91.51.31.50.81.31.71.31.4
Delay disc. indifference point, 2s delay0.00.00.1-0.1-0.3-0.1-0.0-0.10.3-0.0-0.1
Delay disc. indifference point, 24s delay6.66.49.12.62.32.92.02.23.02.42.6
Delay disc. indifference point, 4s delay0.20.20.50.30.20.70.50.50.60.20.5
Delay disc. indifference point, 8s delay0.70.71.30.80.81.00.20.71.21.10.8
Delay discount exponential model param1.31.32.4-1.2-0.9-1.4-0.6-1.0-1.5-1.1-1.2
Delay discount hyperbolic model param1.01.02.0-1.0-0.8-1.2-0.5-0.9-1.4-0.9-1.0
Fecal boli incidents, locomotor time 12.83.04.61.61.91.31.62.21.52.01.7
Change in fecal boli incidents, locomotor task0.90.81.6-0.8-0.8-0.7-1.0-1.0-0.8-1.3-0.9
Time >=10cm from walls, locomotor time 10.20.20.30.60.50.50.60.60.5-0.10.5
Bouts of movement, locomotor time 14.04.45.52.12.31.62.22.42.12.11.9
Total resting periods, locomotor time 15.35.96.92.52.61.82.52.62.42.62.3
Rest time, locomotor task time 13.13.44.51.82.11.31.92.11.81.81.8
Distance moved, locomotor task time 10.20.20.8-0.2-0.80.3-0.5-0.90.20.2-0.2
Vertical activity count, locomotor time 10.70.70.9-0.8-0.9-0.7-0.9-0.9-0.6-1.0-0.7
Time >=10cm from walls, locomotor time 21.11.22.2-1.1-0.9-1.5-0.5-0.8-1.1-1.4-1.2
Bouts of movement, locomotor time 20.70.81.3-1.0-0.9-0.9-0.9-0.8-0.9-0.6-1.2
Total resting periods, locomotor time 20.80.81.4-1.0-0.9-0.9-0.7-0.8-1.0-0.7-1.2
Rest time, locomotor task time 20.30.41.10.40.50.71.10.50.30.50.5
Distance moved, locomotor task time 20.30.41.00.50.30.30.30.41.01.00.5
Vertical activity count, locomotor time 20.10.10.3-0.2-0.3-0.5-0.5-0.10.2-0.1-0.2
Weight adjusted by age0.40.51.00.70.80.80.21.00.10.40.9
Seeking ratio, delayed vs. immediate footshock0.40.40.8-0.5-0.5-0.8-0.2-0.8-0.6-0.7-0.9
Locomotion in novel chamber0.60.71.50.81.20.40.11.10.21.00.9
Locomotion in novel chamber post-restriction1.21.52.21.31.41.10.11.31.01.51.3
Progressive ratio1.11.32.91.31.70.60.81.51.10.70.8
Food seeking constrained by brief footshock0.10.20.70.20.10.1-0.4-0.40.80.5-0.0
Seeking ratio, punishment vs. effort2.02.54.7-1.6-2.1-1.1-1.5-2.2-1.3-1.1-1.4
Run reversals in cocaine runway, females2.52.54.9-1.7-1.4-2.2-1.0-1.5-1.8-1.1-1.6
Run reversals in cocaine runway, males1.61.63.6-1.3-1.9-0.8-0.4-1.8-1.1-0.8-1.2
Latency to leave start box in cocaine runway0.20.20.5-0.30.1-0.5-0.7-0.1-0.7-0.3-0.4
Latency to leave start box in cocaine runway, F0.10.10.3-0.00.2-0.30.40.4-0.5-0.2-0.1
Latency to leave start box in cocaine runway, M1.41.45.7-1.0-0.6-0.9-2.4-1.2-0.8-0.3-0.9
Cd content in liver0.30.30.70.50.20.60.90.60.70.10.6
Co content in liver0.60.71.50.80.70.80.30.71.21.20.9
Cu content in liver0.81.01.21.01.00.90.91.00.91.11.0
Fe content in liver0.30.40.8-0.6-0.7-0.9-0.5-0.5-0.8-0.2-0.6
K content in liver0.90.93.90.60.01.1-0.0-0.21.22.00.8
Mg content in liver0.30.30.9-0.3-0.60.2-0.9-0.70.00.5-0.1
Mn content in liver0.60.71.40.81.10.7-0.50.90.51.20.8
Na content in liver1.71.83.7-1.4-1.7-1.1-1.6-1.9-0.90.3-1.1
Rb content in liver0.70.92.40.80.31.51.40.41.00.40.9
Se content in liver0.10.10.40.1-0.20.5-0.2-0.10.6-0.10.2
Sr content in liver0.60.50.90.80.90.50.50.80.50.90.7
Zn content in liver0.10.10.30.20.2-0.0-0.20.00.20.50.2