Hub : Genes

Trim35

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009449 0.14 0.11 5.0e-09 0.07 0.07 0.06 0.07 9.5e-09 1.7e-08 1.2e-07 2.1e-08
2 Adipose mRNA stability ENSRNOG00000009449 0.03 0.03 3.5e-03 0.02 0.01 0.01 0.01 3.9e-03 1.5e-02 2.1e-02 2.1e-02
3 BLA gene expression ENSRNOG00000009449 0.11 0.07 2.0e-03 0.01 0.04 0.03 0.02 5.9e-02 5.1e-03 9.4e-03 2.7e-02
4 BLA mRNA stability ENSRNOG00000009449 0.36 0.18 1.9e-09 0.13 0.06 0.09 0.09 2.7e-07 3.3e-04 1.5e-05 1.1e-05
5 Brain gene expression ENSRNOG00000009449 0.05 0.03 6.9e-04 0.04 0.04 0.04 0.04 7.8e-05 1.9e-04 1.7e-04 2.4e-04
6 Brain mRNA stability ENSRNOG00000009449 0.75 0.09 0.0e+00 0.43 0.46 0.45 0.45 1.3e-43 1.3e-46 1.0e-45 3.6e-46
7 Liver gene expression ENSRNOG00000009449 0.1 0.07 4.4e-07 0.04 0.04 0.05 0.04 1.3e-05 5.8e-05 3.3e-06 5.5e-05
8 Liver mRNA stability ENSRNOG00000009449 0.03 0.02 1.6e-03 0.02 0.01 0.02 0.01 2.2e-03 7.2e-03 5.6e-03 9.9e-03
9 NAcc gene expression ENSRNOG00000009449 0.06 0.05 1.3e-03 0.02 0.01 0.02 0.01 2.1e-02 2.6e-02 1.2e-02 3.2e-02
10 NAcc mRNA stability ENSRNOG00000009449 0.14 0.08 1.3e-08 0.08 0.07 0.08 0.07 1.7e-06 6.4e-06 2.7e-06 3.7e-06
11 OFC mRNA stability ENSRNOG00000009449 0.22 0.14 4.7e-03 0.04 0.02 0.02 0.03 4.7e-02 9.5e-02 1.3e-01 7.6e-02
12 PL mRNA stability ENSRNOG00000009449 0.63 0.14 0.0e+00 0.3 0.28 0.3 0.3 1.0e-22 9.3e-22 4.9e-23 1.1e-22

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.51.62.8-1.0-0.90.21.70.91.60.61.4-1.31.41.61.5
BMI without tail0.30.72.31.21.0-1.50.4-1.00.41.30.20.80.20.10.1
Body weight0.10.51.6-0.8-1.01.30.31.00.4-1.20.3-0.70.2-0.00.4
Epididymis fat weight0.71.74.22.11.4-1.2-1.1-1.5-0.90.4-1.01.7-1.1-1.5-1.1
Glucose0.81.32.70.5-0.5-0.91.50.51.41.21.6-0.81.61.01.2
Heart weight0.20.31.00.9-0.30.2-0.20.2-0.2-1.00.00.20.1-1.0-0.4
Left kidney weight0.72.05.4-0.1-2.11.80.92.10.9-2.31.2-1.31.1-0.70.7
Right kidney weight0.92.510.11.3-0.51.5-1.30.4-1.1-3.2-1.00.5-1.1-2.9-1.3
Tail length0.92.76.21.91.2-0.3-1.8-1.2-1.7-1.3-1.52.0-1.6-2.5-1.9
Length with tail0.41.55.3-0.0-0.41.4-1.50.4-1.3-2.3-1.10.5-1.2-1.7-1.1
Length without tail1.32.87.5-2.5-2.22.70.22.20.4-2.20.5-2.00.40.50.8
Liver weight, left3.15.19.1-1.2-3.01.62.33.02.3-0.52.6-3.02.41.32.2
Liver weight, right1.82.94.3-1.4-2.11.11.82.01.9-0.21.8-1.92.01.61.9
Parametrial fat weight2.65.08.32.52.9-2.6-1.9-2.9-2.01.8-2.02.5-2.0-1.4-2.0
Retroperitoneal fat weight0.31.02.51.21.5-1.6-0.2-1.5-0.31.1-0.41.2-0.4-0.2-0.5
Intraocular pressure1.01.42.40.81.3-0.7-1.3-1.3-1.30.3-1.51.5-1.3-0.8-1.3
Extensor digitorum longus weight7.128.651.7-7.2-6.15.24.96.14.9-1.64.5-6.44.95.25.3
Soleus weight0.61.73.4-1.6-1.00.51.41.01.40.71.2-1.51.41.81.5
Tibialis anterior weight4.916.828.8-5.4-4.94.33.55.03.6-1.63.4-5.13.43.64.0
Tibia length2.26.214.51.70.31.1-3.0-0.3-2.9-3.3-2.61.7-3.0-3.8-2.9
Number of licking bursts0.30.31.0-0.20.4-0.80.6-0.40.41.00.40.30.40.80.4
Food consumed during 24 hour testing period0.70.93.41.0-1.11.0-0.31.1-0.1-1.90.2-0.40.1-1.5-0.3
Times rat made contact with spout0.20.21.41.20.0-0.50.2-0.00.30.10.30.30.3-0.50.1
Mean time between licks in bursts2.83.96.91.62.6-1.6-2.1-2.6-2.00.4-2.22.6-1.5-1.5-2.1
Mean num. licks in bursts0.20.31.20.9-0.40.4-0.30.4-0.1-0.8-0.1-0.2-0.0-1.1-0.2
Std. dev. time between licks in bursts5.46.411.61.62.3-0.3-3.0-2.3-3.0-0.9-3.42.8-2.8-2.8-3.2
Water consumed over 24 hours0.60.81.6-0.8-1.21.30.71.20.8-0.80.5-0.90.80.20.7
Indifference point 0 sec4.47.014.71.71.01.0-3.4-0.9-3.2-2.9-3.12.0-3.2-3.8-3.3
Indifference point AUC3.54.18.3-1.2-1.30.22.91.22.91.42.2-1.52.52.22.7
Indifference point function ln k1.21.73.90.60.40.4-2.0-0.3-1.9-1.4-1.40.7-1.6-1.5-1.8
Indifference point function log k1.21.73.90.60.40.4-2.0-0.3-1.9-1.4-1.40.7-1.6-1.5-1.8
Delay discounting total patch changes 0 sec3.96.413.51.50.71.1-3.2-0.6-3.1-3.0-2.81.7-3.0-3.7-3.1
Delay discounting total patch changes 12 sec0.50.71.80.40.10.6-0.9-0.1-0.9-1.0-1.00.5-0.9-1.3-1.0
Delay discounting total patch changes 18 sec0.30.41.51.00.4-0.2-0.5-0.3-0.7-0.6-0.40.7-0.3-1.2-0.9
Delay discounting total patch changes 24 sec1.01.34.10.1-0.31.3-1.20.4-1.2-2.0-1.20.4-1.0-1.6-1.3
Delay discounting total patch changes 6 sec0.20.30.70.30.20.2-0.7-0.1-0.5-0.7-0.50.5-0.6-0.9-0.6
Delay discounting time to switch 0 sec0.91.42.50.51.3-0.9-1.3-1.2-1.60.3-1.31.3-1.4-0.6-1.5
Delay discounting water rate 0 sec0.40.61.6-0.7-1.01.30.41.00.7-1.00.4-0.60.60.10.6
Delay discounting water rate 12 sec0.30.52.0-0.6-0.91.1-0.40.9-0.2-1.40.0-0.5-0.2-0.3-0.1
Delay discounting water rate 18 sec2.63.45.9-1.4-2.41.71.52.41.8-1.22.1-2.41.81.11.8
Delay discounting water rate 24 sec0.50.61.90.2-0.6-0.30.80.50.90.41.4-1.01.20.60.8
Delay discounting water rate 6 sec1.21.84.7-1.3-2.02.20.41.90.7-1.80.7-1.40.60.10.8
Locomotor activity2.33.613.3-1.2-1.53.0-1.71.5-1.6-3.6-1.4-0.1-1.7-1.7-1.2
Locomotor testing distance3.96.511.50.30.61.6-3.4-0.5-3.3-3.1-3.21.9-3.4-3.0-3.0
Locomotor testing rearing6.19.517.00.90.91.7-4.1-0.9-3.9-3.3-4.12.4-4.1-3.8-3.6
Light reinforcement 11.01.96.52.61.3-1.8-0.9-1.4-0.90.9-0.91.5-0.6-1.3-1.3
Light reinforcement 21.01.34.31.30.7-1.90.8-0.71.02.11.10.31.20.70.6
Reaction time number correct0.30.42.2-0.70.0-0.70.3-0.30.31.50.40.00.31.30.5
Reaction time mean minus median0.10.20.5-0.5-0.10.7-0.40.2-0.5-0.6-0.5-0.1-0.4-0.3-0.4
Reaction time mean minus median AUC0.10.10.2-0.2-0.10.3-0.20.1-0.4-0.3-0.3-0.0-0.1-0.2-0.4
Reaction time num false alarms0.30.41.20.30.20.2-1.1-0.2-0.9-0.4-0.80.3-0.9-0.7-0.8
Reaction time num false alarms AUC0.20.30.70.4-0.30.3-0.90.2-0.7-0.6-0.3-0.1-0.7-0.7-0.6
Reaction time trials correct on left0.30.42.2-0.70.0-0.70.3-0.30.31.50.40.00.31.30.5
Reaction time trials on left0.30.42.3-0.50.1-0.70.2-0.40.21.50.40.10.21.20.4
Reaction time mean0.10.10.3-0.5-0.30.60.30.30.3-0.40.1-0.30.30.10.3
Reaction time mean AUC0.10.20.7-0.7-0.40.80.20.40.1-0.60.0-0.50.10.10.2
Median of all reaction times0.10.10.2-0.3-0.40.40.40.20.4-0.20.4-0.40.40.20.4
Reaction time omissions1.62.23.31.41.8-1.3-1.5-1.8-1.80.7-1.41.3-1.5-1.1-1.8
Reaction time false alarm rate0.20.41.10.7-0.00.4-0.70.2-0.5-0.9-0.4-0.1-0.6-1.1-0.6
Reaction time premature initiation rate0.70.92.0-1.0-0.70.61.00.71.40.10.8-0.61.21.01.3
Reaction time premature initiations0.91.32.8-1.3-0.70.21.20.61.50.91.0-0.61.21.71.5
Std. dev. reaction times0.00.10.2-0.4-0.10.40.10.2-0.1-0.40.1-0.30.2-0.00.0
Reaction time trials completed0.30.42.3-0.50.1-0.70.2-0.40.21.50.40.10.21.20.4
Reaction time trials AUC0.30.42.1-0.60.1-0.70.2-0.40.21.50.40.10.21.10.4
Social response proportion1.11.23.9-0.00.8-1.70.8-0.90.92.00.70.31.21.60.8
Social responses3.14.06.62.32.5-2.4-1.7-2.6-1.51.6-1.82.5-1.4-1.0-1.7
Social time0.91.22.81.00.20.3-1.4-0.2-1.2-1.1-1.40.9-1.1-1.7-1.3
Conditioned locomotion0.40.52.4-0.10.8-0.90.4-0.90.41.60.00.30.30.80.4
Cocaine response after cond. corrected1.92.16.3-0.80.2-1.31.4-0.21.42.51.4-0.61.72.41.4
Cocaine response after cond. not corrected1.01.24.0-0.60.4-1.00.9-0.40.92.00.9-0.31.11.80.9
Cocaine response before conditioning1.72.04.00.70.50.7-1.8-0.4-1.8-1.7-1.61.0-1.8-2.0-1.7
Saline control response0.60.81.90.60.00.5-1.2-0.0-1.0-1.2-1.00.4-1.2-1.4-1.0
Condit. Reinf. active minus inactive responses0.30.30.90.50.6-0.1-0.6-0.6-0.4-0.1-0.90.7-0.7-0.6-0.5
Condit. Reinf. active-inactive response ratio0.40.41.0-0.4-0.20.00.90.31.00.50.6-0.60.70.71.0
Condit. Reinf. active responses0.70.91.51.11.0-0.4-1.1-1.0-0.8-0.2-1.21.0-1.1-1.2-0.9
Condit. Reinf. inactive responses2.53.14.31.81.7-0.9-2.1-1.8-1.9-0.2-2.01.8-1.9-2.0-2.0
Condit. Reinf. lever presses0.81.13.80.2-0.41.1-1.20.4-1.1-2.0-0.9-0.0-1.1-1.5-1.0
Condit. Reinf. lever reinforcers received0.40.61.31.00.6-0.1-0.9-0.7-0.6-0.4-1.00.7-0.8-1.2-0.7
Pavlov. Cond. lever latency1.01.44.90.91.6-1.9-0.1-1.6-0.12.2-0.31.2-0.20.5-0.3
Pavlov. Cond. magazine entry latency0.60.73.40.3-0.71.0-0.60.7-0.5-1.9-0.2-0.1-0.2-1.3-0.5
Pavlov. Cond. change in total contacts1.72.35.3-1.5-2.22.30.42.20.6-2.20.8-1.80.80.00.7
Pavlov. Cond. index score1.11.46.1-0.8-1.52.0-0.21.5-0.1-2.50.1-0.90.1-0.80.0
Pavlov. Cond. latency score1.01.36.2-0.6-1.31.9-0.51.2-0.3-2.5-0.2-0.6-0.1-1.0-0.2
Pavlov. Cond. lever contacts1.21.77.1-0.9-1.62.2-0.41.6-0.3-2.7-0.1-1.1-0.2-0.9-0.2
Pavlov. Cond. magazine entry number0.50.62.6-0.40.3-0.80.8-0.30.61.60.6-0.30.51.20.7
Pavlov. Cond. intertrial magazine entries5.57.110.62.83.3-2.4-2.5-3.2-2.41.1-2.73.2-2.8-2.1-2.6
Pavlov. Cond. lever-magazine prob. diff.1.01.35.3-0.9-1.51.9-0.11.50.1-2.30.2-1.00.3-0.60.2
Pavlov. Cond. response bias1.31.87.8-1.0-1.62.3-0.41.6-0.4-2.8-0.1-1.0-0.2-1.0-0.2
Conditioned reinforcement - actives0.90.82.01.41.2-1.2-0.6-1.2-0.40.5-0.31.1-0.5-0.8-0.7
Conditioned reinforcement - inactives1.82.04.41.91.2-0.4-1.5-1.2-1.2-0.7-1.31.8-1.4-2.1-1.4
Conditioned locomotion0.20.31.01.00.7-0.60.1-0.70.30.30.00.60.1-0.6-0.1
Intermittent access intake day 1-15 change0.30.31.11.00.4-0.4-0.3-0.4-0.20.2-0.60.9-0.2-0.8-0.3
Intermittent access intake escalation0.10.10.30.60.2-0.20.1-0.20.10.3-0.30.50.1-0.30.0
Intermittent access intake escalation 20.10.10.20.5-0.0-0.00.00.00.00.0-0.40.40.1-0.30.0
Intermitt. access day 1 inactive lever presses0.30.30.90.00.8-0.8-0.2-0.8-0.21.0-0.50.7-0.40.4-0.1
Intermitt. access day 15 inactive lever presses0.10.10.20.1-0.50.30.30.50.4-0.20.4-0.40.3-0.10.4
Intermitt. access escalation Index0.10.10.4-0.60.1-0.10.1-0.10.10.40.1-0.10.00.60.3
Intermittent access day 1 total infusions0.40.51.20.2-0.60.10.70.61.1-0.21.1-0.61.00.00.8
Intermittent access day 15 total infusions0.20.20.60.60.1-0.50.5-0.10.80.60.50.20.70.10.6
Intermittent access terminal intake (last 3 days)0.80.81.90.0-0.7-0.11.20.71.40.41.3-0.61.40.61.2
Intermittent access total infusions0.40.41.00.60.2-0.80.7-0.21.00.80.90.10.90.30.7
Intermittent access day 1 locomotion0.30.31.40.90.40.0-0.5-0.4-0.2-0.7-0.30.5-0.3-1.2-0.4
Intermittent access day 15 total locomotion0.30.31.51.20.1-0.50.3-0.10.60.00.50.20.7-0.60.2
Intermittent access total locomotion0.10.20.70.70.20.1-0.1-0.20.3-0.5-0.00.50.1-0.9-0.0
Intermittent access standard deviation0.40.50.90.6-1.00.50.71.00.7-0.70.6-0.50.7-0.50.5
Cocaine induced anxiety0.91.03.4-0.8-0.71.6-1.00.7-1.0-1.8-0.7-0.3-0.8-0.9-0.8
Post-drug Anxiety2.42.74.71.11.5-0.8-2.2-1.5-2.1-0.0-1.81.9-1.9-1.4-2.0
Baseline Anxiety2.22.34.41.71.8-1.7-1.4-1.8-1.40.8-1.42.1-1.4-1.0-1.5
Lifetime Intake0.20.20.60.60.1-0.40.4-0.10.80.20.50.20.6-0.20.5
Incentive Sensitization - Responses0.60.62.01.2-0.60.60.10.60.4-1.20.6-0.20.4-1.40.1
Incentive Sensitization - Breakpoint0.60.62.71.4-0.50.50.00.50.3-1.30.50.00.3-1.60.0
Progressive ratio test 1 active lever presses1.51.53.4-0.2-0.6-0.61.70.61.61.01.7-1.01.81.31.4
Progressive ratio test 1 breakpoint1.61.63.4-0.1-0.5-0.81.70.51.71.21.7-0.91.81.31.5
Progressive ratio test 1 inactive lever presses0.60.61.41.10.9-1.2-0.6-0.9-0.50.9-0.40.9-0.5-0.3-0.6
Progressive ratio test 2 active lever presses0.90.92.40.8-0.4-0.61.30.41.40.41.6-0.51.60.21.1
Progressive ratio test 2 breakpoint0.70.82.10.9-0.5-0.31.20.51.30.01.4-0.41.4-0.21.0
Progressive ratio test 2 inactive lever presses0.20.20.91.0-0.0-0.10.20.00.4-0.40.60.10.4-0.80.1
Total sessions with >9 infusions0.40.41.00.41.0-0.9-0.3-1.0-0.10.9-0.30.9-0.20.1-0.2
Short access day 1 total inactive lever presses0.91.02.80.9-0.50.21.20.51.7-0.51.3-0.51.4-0.61.3
Short access day 10 total inactive lever presses0.50.52.00.80.8-1.2-0.2-0.8-0.21.4-0.40.6-0.30.2-0.1
Short access day 1 total infusions0.40.51.2-0.40.1-0.20.8-0.11.10.60.8-0.11.00.70.9
Short access day 10 total infusions0.40.41.40.1-0.91.00.20.90.5-1.20.5-0.40.4-0.50.3
Short access total infusions0.20.20.40.4-0.30.30.30.30.6-0.50.50.10.5-0.50.4
Short access day 1 locomotion0.20.20.9-0.3-0.60.9-0.30.6-0.2-0.9-0.1-0.2-0.0-0.4-0.2
Short access day 10 total locomotion0.70.72.00.90.70.0-0.9-0.7-0.7-0.9-0.80.8-1.0-1.4-0.8
Short access total locomotion0.70.81.80.90.60.1-1.0-0.6-0.8-0.8-0.91.0-0.9-1.4-1.0
Compulsive drug intake0.40.41.2-0.10.5-0.0-1.0-0.5-1.1-0.2-0.50.3-1.0-0.3-1.0
One hour access (0.3 mA shock)0.10.10.40.6-0.3-0.00.10.30.3-0.30.40.00.4-0.50.1
One hour access (shock baseline)0.40.41.4-0.0-0.40.21.00.41.20.00.7-0.31.00.20.9
Number of responses in last shaping day0.50.52.1-0.3-0.71.1-0.50.7-0.7-1.5-0.4-0.2-0.2-0.7-0.7
Context. condit. distance diff. score2.53.110.11.11.4-2.71.7-1.41.73.21.40.41.71.51.3
Locomotion velocity, session 10.30.31.1-0.40.50.3-0.6-0.5-0.6-0.2-1.10.5-0.6-0.2-0.6
Locomotion distance, session 10.91.23.40.10.31.3-0.9-0.3-0.8-1.5-1.80.9-1.3-1.5-1.0
Locomotion velocity, session 20.50.61.4-0.4-0.01.0-0.80.0-0.8-1.1-1.20.3-0.9-0.7-0.8
Locomotion distance, session 21.42.05.1-0.00.41.3-1.6-0.4-1.4-1.6-2.31.1-1.9-1.6-1.5
Locomotion velocity, session 31.41.72.6-1.0-1.10.41.61.11.50.41.6-1.51.61.31.5
Locomotion distance, session 30.50.61.1-0.2-0.2-0.40.90.21.00.91.0-0.51.10.90.9
Stereotopy head waving bouts, day 30.20.31.3-1.1-0.40.90.20.40.3-0.3-0.1-0.40.10.50.4
Stereotopy head waving duration, day 31.31.53.4-1.7-1.51.80.91.50.9-1.20.6-1.50.70.61.0
Locomotion velocity, session 73.03.311.32.31.9-3.41.1-1.91.03.10.91.11.10.60.6
Locomotion distance, session 73.03.812.72.72.6-3.6-0.3-2.6-0.32.9-0.31.8-0.3-0.2-0.6
Stereotopy head waving bouts, day 71.21.33.4-1.4-1.41.90.81.41.0-1.20.6-1.20.90.41.0
Stereotopy head waving duration, day 72.32.84.6-2.0-1.92.11.51.91.7-1.11.2-1.81.61.11.7
Locomotion velocity, session 80.70.81.9-0.6-0.1-0.21.30.11.40.80.8-0.51.11.21.2
Locomotion distance, session 80.40.61.40.91.2-1.00.4-1.20.61.0-0.40.90.2-0.10.2
Degree of sensitization distance4.24.310.02.92.7-3.2-1.2-2.7-1.31.9-1.12.3-1.4-1.1-1.5
Degree of sensitization stereotypy1.21.32.2-1.2-1.41.51.01.41.1-1.00.9-1.21.00.51.1
Condit. Reinf. active minus inactive responses0.30.41.7-0.6-0.51.0-0.40.5-0.6-1.3-0.3-0.0-0.3-0.4-0.4
Condit. Reinf. active-inactive response ratio0.60.62.1-1.5-0.50.60.80.50.70.10.5-0.60.91.20.9
Condit. Reinf. active responses1.11.33.40.20.00.9-1.3-0.0-1.5-1.8-1.20.8-1.3-1.5-1.4
Condit. Reinf. inactive responses3.84.510.42.01.00.2-2.4-1.0-2.5-2.0-2.31.9-2.4-3.2-2.6
Incentive salience index mean0.91.14.6-0.8-0.91.6-0.70.9-0.9-2.1-0.5-0.2-0.7-0.8-0.7
Condit. Reinf. lever presses1.31.86.6-0.4-0.81.7-1.30.8-1.5-2.6-1.00.1-1.3-1.5-1.2
Time in familiar zone, hab. session 10.20.20.40.30.5-0.6-0.2-0.5-0.20.6-0.20.3-0.40.1-0.1
Time in novel zone, hab. session 11.91.92.9-1.4-1.40.71.51.41.40.01.6-1.61.71.41.5
Total zone transitions, hab. session 10.30.41.3-0.2-0.51.1-0.40.5-0.2-1.2-0.50.0-0.5-0.7-0.2
Total locomotion distance, hab. session 10.71.01.80.30.30.7-1.2-0.3-1.1-1.2-1.30.8-1.4-1.3-1.1
Locomotion velocity, hab. session 11.72.54.40.60.50.9-2.0-0.5-1.8-1.7-2.11.4-2.1-2.1-1.8
Time in familiar zone, hab. session 21.11.24.5-0.90.3-1.10.6-0.30.72.10.9-0.30.82.10.9
Time in novel zone, hab. session 20.60.62.30.4-0.20.9-0.50.2-0.6-1.5-0.70.1-0.6-1.4-0.7
Total zone transitions, hab. session 20.70.93.9-1.3-1.02.0-0.11.0-0.0-1.6-0.4-0.6-0.2-0.20.1
Total locomotion distance, hab. session 20.20.31.1-0.6-0.21.1-0.40.2-0.4-0.9-0.6-0.1-0.5-0.4-0.3
Locomotion velocity, hab. session 20.40.52.2-0.9-0.51.5-0.30.5-0.3-1.2-0.6-0.2-0.5-0.4-0.2
Novel to familiar place preference ratio0.80.92.20.50.10.1-1.2-0.1-1.5-0.9-0.90.5-1.3-1.1-1.4
Novelty place preference1.01.02.60.40.20.1-1.3-0.2-1.6-0.8-1.00.6-1.4-1.0-1.5
Time in novel zone, NPP test0.80.82.10.10.20.3-1.2-0.2-1.5-0.9-1.00.5-1.3-0.8-1.3
Total zone transitions, NPP test0.81.12.80.50.70.6-1.1-0.7-0.9-1.0-1.71.2-1.3-1.4-1.1
Total locomotion distance, NPP test3.95.38.72.02.2-0.6-2.6-2.2-2.4-0.7-2.92.7-2.7-2.7-2.7
Locomotion velocity, NPP test3.24.66.82.02.0-0.6-2.4-2.0-2.3-0.6-2.62.4-2.5-2.5-2.5
Pavlov. Cond. lever latency0.60.72.7-0.20.7-1.00.8-0.70.91.60.30.10.81.20.7
Pavlov. Cond. magazine entry latency0.10.20.70.7-0.40.2-0.20.4-0.1-0.70.2-0.2-0.1-0.8-0.1
Pavlov. Cond. change in total contacts1.61.75.6-1.0-1.82.1-0.11.8-0.1-2.40.3-1.3-0.0-0.50.1
Pavlov. Cond. index score0.50.62.60.1-1.11.1-0.21.1-0.2-1.60.2-0.6-0.2-0.9-0.1
Pavlov. Cond. latency score0.50.62.70.3-0.91.0-0.40.9-0.5-1.60.0-0.4-0.4-1.1-0.4
Pavlov. Cond. lever contacts0.60.73.10.2-0.91.1-0.40.9-0.4-1.80.0-0.3-0.4-1.1-0.4
Pavlov. Cond. magazine entry number0.50.61.50.11.2-1.1-0.3-1.2-0.31.2-0.60.8-0.40.4-0.4
Pavlov. Cond. intertrial magazine entries1.11.32.40.30.40.5-1.5-0.4-1.5-1.2-1.40.8-1.3-1.4-1.5
Pavlov. Cond. lever-magazine prob. diff.0.60.82.7-0.1-1.31.30.11.30.1-1.70.4-0.80.1-0.70.1
Pavlov. Cond. response bias0.60.81.9-0.1-1.41.10.41.40.4-1.30.9-1.00.5-0.40.5
Bone: apparent density1.32.12.91.61.5-1.2-1.6-1.5-1.50.2-1.51.7-1.6-1.2-1.6
Bone surface1.11.93.51.10.9-0.4-1.9-0.8-1.8-0.6-1.61.3-1.7-1.5-1.8
Bone volume1.22.03.61.11.0-0.5-1.9-1.0-1.9-0.6-1.61.3-1.7-1.5-1.8
Bone: connectivity density2.33.66.01.92.4-2.0-1.8-2.4-1.61.1-2.02.4-1.7-1.2-1.7
Bone: cortical apparent density0.71.02.60.4-0.2-1.21.00.30.81.61.5-0.71.11.00.8
Bone: cortical area0.20.41.30.4-0.70.6-0.30.8-0.4-1.10.1-0.4-0.3-0.9-0.3
Bone: cortical porosity0.80.83.1-1.2-1.11.80.01.10.0-1.5-0.1-0.7-0.1-0.10.1
Bone: cortical porosity0.80.93.4-0.9-1.21.8-0.21.1-0.2-1.9-0.2-0.6-0.2-0.5-0.1
Bone: cortical thickness0.20.30.80.2-0.90.40.20.90.1-0.80.6-0.70.2-0.40.1
Bone: cortical thickness0.30.30.90.2-0.2-0.70.60.30.30.91.0-0.50.50.50.5
Bone: cortical tissue density0.91.22.80.3-0.3-1.21.20.30.91.71.7-0.91.21.11.0
Bone: elastic displacement1.01.22.30.20.20.9-1.3-0.2-1.2-1.5-1.40.8-1.3-1.3-1.2
Bone: elastic work2.02.67.00.3-0.31.6-1.90.3-1.7-2.6-1.80.7-1.8-2.3-1.7
Bone: endosteal estimation0.10.30.60.3-0.00.2-0.80.0-0.7-0.6-0.60.3-0.8-0.6-0.7
Bone: endosteal perimeter0.51.02.00.20.30.6-1.4-0.3-1.2-1.1-1.40.9-1.4-1.2-1.2
Bone: final force0.10.20.6-0.0-0.70.4-0.30.7-0.3-0.80.2-0.4-0.3-0.4-0.2
Bone: final moment0.30.51.80.1-0.80.7-0.70.8-0.8-1.3-0.1-0.3-0.7-0.9-0.6
Bone: marrow area0.20.40.80.40.10.2-0.9-0.1-0.8-0.6-0.70.4-0.9-0.8-0.8
Bone: maximum diameter0.30.51.2-0.4-1.00.90.61.10.7-0.60.6-0.90.60.10.7
Bone: maximum force0.30.61.9-0.3-1.11.0-0.41.2-0.4-1.40.1-0.7-0.4-0.5-0.2
Bone: maximum moment0.61.03.7-0.1-1.21.2-0.91.2-1.0-1.9-0.2-0.5-0.9-1.1-0.7
Bone: minimum diameter0.51.04.00.0-1.01.3-0.81.0-0.8-2.0-0.4-0.3-0.9-1.3-0.6
Bone: periosteal estimation0.20.41.00.5-0.40.4-0.70.4-0.7-0.9-0.40.0-0.7-1.0-0.6
Bone: periosteal perimeter0.30.51.10.40.10.4-0.9-0.1-0.8-0.9-0.90.5-1.0-1.0-0.8
Bone: post-yield work0.60.82.60.5-0.4-1.01.00.40.81.11.6-0.81.10.70.9
Bone: stiffness0.30.40.8-0.5-0.90.40.60.90.7-0.10.7-0.90.60.50.7
Bone: tissue strength0.50.40.90.30.00.2-0.9-0.1-0.9-0.8-0.70.4-0.9-0.8-0.9
Bone: trabecular number1.82.84.21.91.9-1.4-1.7-1.9-1.60.4-1.72.1-1.6-1.5-1.8
Bone: trabecular spacing1.72.23.3-1.8-1.61.51.51.61.5-0.51.3-1.81.41.21.6
Bone: trabecular thickness0.70.91.71.20.3-0.3-1.2-0.3-1.2-0.5-0.70.7-1.2-1.3-1.2
Bone: trabecular tissue density0.70.91.8-1.3-1.31.10.61.30.3-0.61.0-1.30.60.80.6
Breakpoint value in progressive ratio session0.30.30.9-0.30.6-0.4-0.4-0.7-0.40.9-0.70.5-0.60.4-0.4
Distance traveled before self-admin0.80.82.3-1.5-1.01.50.31.00.4-1.30.4-0.80.30.40.6
Distance traveled after self-admin1.21.32.1-1.5-1.11.11.21.21.3-0.30.9-1.01.01.11.4
Delta time in closed arm before/after self-admin0.20.20.60.70.5-0.1-0.2-0.60.1-0.2-0.40.5-0.1-0.7-0.2
Delta time in open arm before/after self-admin0.20.20.90.30.6-0.90.0-0.6-0.10.8-0.20.5-0.10.3-0.2
Diff in mean of infusions in LGA sessions0.30.41.3-1.2-0.71.10.20.70.0-0.4-0.0-0.50.00.50.1
Extinction: sum of active levers before priming1.61.63.81.91.4-1.3-1.0-1.6-0.90.5-1.01.6-1.1-1.3-1.1
Active lever presses in extinction session 60.30.31.20.90.2-1.1-0.1-0.4-0.10.90.10.1-0.2-0.1-0.0
Delta distance traveled before/after self-admin1.21.32.5-1.0-0.70.11.50.71.41.01.1-1.11.21.61.5
Delta ambulatory time before/after self-admin1.01.11.9-1.0-0.70.31.40.81.20.80.9-1.11.01.31.3
Time in closed arm before self-admin0.60.71.7-1.3-0.70.50.80.80.60.10.5-0.80.91.20.7
Time in closed arm after self-admin0.10.10.7-0.8-0.10.5-0.10.0-0.2-0.3-0.3-0.30.00.3-0.1
Time in open arm before self-admin0.20.20.60.00.20.2-0.8-0.3-0.6-0.2-0.50.2-0.8-0.4-0.6
Time in open arm after self-admin0.30.30.80.70.8-0.9-0.1-0.7-0.00.6-0.30.8-0.3-0.1-0.2
Sum of active levers in priming session hrs 5-60.80.83.70.61.1-1.70.0-1.0-0.01.90.20.5-0.00.7-0.1
Time to tail flick, vehicle, before self-admin0.50.51.51.00.20.1-0.8-0.0-0.7-1.2-0.30.1-0.7-1.2-0.7
Time to tail flick, vehicle, after self-admin2.12.26.6-2.1-0.70.41.50.91.40.91.2-1.51.52.61.6
Time to tail flick, test, before self-admin0.70.72.31.10.4-0.0-0.5-0.5-0.5-0.7-0.81.2-0.7-1.5-0.8
Time to tail flick, test, after self-admin4.14.210.52.43.1-3.2-1.1-2.9-0.92.5-1.12.2-0.8-0.4-1.2
Delta time to tail flick, vehicle, before/after SA1.41.34.0-1.1-0.3-0.61.30.31.11.71.1-0.71.32.01.1
Delta time to tail flick, test, before/after SA2.22.08.30.91.9-2.60.0-1.60.22.90.30.40.41.20.1
Ambulatory time before self-admin0.40.51.5-0.8-0.81.20.10.80.3-1.20.3-0.40.0-0.10.4
Ambulatory time after self-admin1.71.93.3-1.8-1.41.61.41.41.5-0.61.0-1.31.01.21.7
Total heroin consumption1.21.53.8-1.2-2.01.40.61.90.4-1.01.0-1.90.50.50.6
Area under the delay curve0.20.20.7-0.0-0.60.5-0.20.6-0.3-0.90.2-0.30.0-0.3-0.1
Delay disc. indifference point, 0s delay1.51.63.10.60.80.3-1.5-0.8-1.5-1.0-1.81.3-1.8-1.5-1.5
Delay disc. indifference point, 16s delay0.10.10.40.3-0.3-0.10.20.30.3-0.00.6-0.20.60.00.2
Delay disc. indifference point, 2s delay0.70.82.4-0.8-0.31.3-0.90.3-1.1-1.6-1.00.0-1.0-0.6-0.8
Delay disc. indifference point, 24s delay0.30.30.6-0.4-0.60.20.40.60.4-0.00.7-0.70.70.50.6
Delay disc. indifference point, 4s delay0.70.81.5-1.1-1.20.90.41.20.4-0.70.9-1.20.80.70.5
Delay disc. indifference point, 8s delay0.20.20.60.4-0.80.2-0.00.8-0.1-0.70.7-0.60.3-0.3-0.0
Delay discount exponential model param0.30.40.90.30.9-0.7-0.1-0.9-0.10.9-0.60.7-0.40.1-0.2
Delay discount hyperbolic model param0.50.51.40.61.1-1.0-0.1-1.1-0.01.2-0.60.9-0.40.0-0.2
Fecal boli incidents, locomotor time 11.01.13.6-0.3-1.90.80.51.90.2-1.01.3-1.50.60.00.4
Change in fecal boli incidents, locomotor task0.50.51.8-0.90.7-0.70.0-0.7-0.11.30.10.3-0.11.30.2
Time >=10cm from walls, locomotor time 11.11.12.31.10.8-0.3-1.1-0.8-1.2-0.7-1.01.0-1.5-1.3-1.2
Bouts of movement, locomotor time 11.71.93.9-1.9-0.80.81.80.81.80.70.9-0.71.32.01.7
Total resting periods, locomotor time 12.62.96.3-1.9-0.70.42.30.72.31.41.4-1.01.92.52.2
Rest time, locomotor task time 12.52.75.7-1.5-0.70.12.20.72.11.41.7-1.41.92.42.1
Distance moved, locomotor task time 11.71.83.71.20.9-0.4-1.9-0.9-1.8-0.8-1.51.0-1.4-1.7-1.7
Vertical activity count, locomotor time 11.61.75.6-0.3-0.41.5-1.60.4-1.5-2.4-1.3-0.1-1.3-1.5-1.2
Time >=10cm from walls, locomotor time 20.10.10.3-0.4-0.40.40.10.4-0.0-0.10.2-0.5-0.10.30.2
Bouts of movement, locomotor time 22.02.15.6-1.8-0.80.01.50.81.41.31.3-1.41.92.41.4
Total resting periods, locomotor time 23.33.57.8-1.9-1.1-0.02.11.12.01.52.0-1.82.42.82.0
Rest time, locomotor task time 25.76.612.2-1.0-2.00.13.42.03.41.23.5-2.73.32.53.1
Distance moved, locomotor task time 23.64.28.11.51.20.0-2.8-1.2-2.7-1.6-2.41.6-2.3-2.5-2.6
Vertical activity count, locomotor time 22.42.65.9-0.0-0.01.5-2.20.0-2.1-2.4-1.80.5-1.8-1.9-1.8
Weight adjusted by age0.80.93.0-1.0-1.21.70.21.1-0.2-1.5-0.1-1.30.0-0.10.0
Seeking ratio, delayed vs. immediate footshock1.41.73.31.00.80.5-1.3-0.7-1.3-1.6-1.61.4-1.4-1.8-1.5
Locomotion in novel chamber0.10.10.50.4-0.10.0-0.2-0.0-0.1-0.70.4-0.30.0-0.4-0.2
Locomotion in novel chamber post-restriction1.01.23.2-0.9-0.80.91.40.81.8-0.10.9-0.91.10.71.6
Progressive ratio0.40.51.2-0.4-0.91.10.71.00.7-0.90.4-0.80.3-0.10.6
Food seeking constrained by brief footshock3.23.98.3-1.30.1-0.92.4-0.22.62.71.7-1.02.42.92.4
Seeking ratio, punishment vs. effort0.81.03.0-0.50.4-1.00.9-0.51.01.70.8-0.21.41.51.0
Run reversals in cocaine runway, females0.90.92.61.61.2-0.7-0.2-1.20.10.2-0.61.5-0.3-1.3-0.4
Run reversals in cocaine runway, males5.65.48.6-1.9-2.92.52.52.92.5-1.32.3-2.62.01.02.6
Latency to leave start box in cocaine runway1.41.62.6-1.5-1.11.11.41.11.4-0.11.0-1.41.41.31.6
Latency to leave start box in cocaine runway, F2.42.74.0-2.0-1.81.61.61.91.6-0.41.4-2.01.41.51.9
Latency to leave start box in cocaine runway, M0.50.51.10.61.0-0.4-0.6-1.1-0.30.1-0.81.1-0.3-0.6-0.6
Cd content in liver0.30.30.80.40.2-0.1-0.6-0.2-0.9-0.5-0.40.4-0.6-0.7-0.8
Co content in liver2.42.95.3-1.9-1.20.61.91.22.00.91.6-1.71.92.32.0
Cu content in liver1.11.32.1-1.1-1.00.61.31.01.40.41.1-1.31.31.21.5
Fe content in liver0.60.82.81.71.0-1.0-0.5-1.0-0.20.5-0.51.1-0.5-1.0-0.5
K content in liver0.50.51.30.61.1-0.9-0.2-1.1-0.10.7-0.41.0-0.2-0.0-0.3
Mg content in liver0.40.41.00.91.0-0.7-0.0-1.00.20.5-0.40.9-0.0-0.3-0.1
Mn content in liver1.92.23.91.61.9-1.1-1.3-1.9-1.20.2-1.62.0-1.3-1.4-1.4
Na content in liver2.42.510.3-1.1-1.72.9-0.71.7-0.5-3.2-0.6-0.9-0.7-1.2-0.4
Rb content in liver0.30.31.10.60.5-1.00.4-0.50.31.00.50.20.40.30.4
Se content in liver2.73.26.60.41.00.9-2.2-1.0-2.1-1.7-2.61.7-2.2-2.2-2.0
Sr content in liver0.60.61.20.51.1-0.4-0.6-1.1-0.50.4-1.11.0-0.6-0.5-0.6
Zn content in liver0.91.03.7-1.0-1.21.9-0.31.2-0.4-1.9-0.4-0.7-0.3-0.7-0.2