Hub : Genes

Gucy1b2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000009440 0.27 0.11 5.6e-17 0.3 0.29 0.29 0.3 1.6e-16 1.2e-15 4.1e-16 2.4e-16
2 Brain gene expression ENSRNOG00000009440 0.23 0.1 0.0e+00 0.25 0.25 0.26 0.26 2.0e-23 5.6e-23 8.3e-24 4.0e-24
3 IL gene expression ENSRNOG00000009440 0.22 0.14 2.6e-03 0.05 0.02 -0.01 0.01 2.3e-02 9.6e-02 5.0e-01 2.0e-01
4 Liver alternative polyA ENSRNOT00000012948 0.23 0.11 0.0e+00 0.22 0.21 0.22 0.22 1.4e-23 2.2e-23 1.5e-23 1.1e-23
5 Liver alternative polyA ENSRNOT00000081912 0.36 0.14 0.0e+00 0.21 0.21 0.21 0.22 3.5e-23 1.3e-22 1.5e-22 1.9e-23
6 Liver alternative TSS ENSRNOT00000012948 0.02 0.02 3.2e-03 0.01 0.02 0.01 0.01 2.2e-02 5.7e-03 4.7e-02 1.3e-02
7 Liver alternative TSS ENSRNOT00000081912 0.02 0.02 3.4e-03 0.01 0.02 0.01 0.01 2.4e-02 5.7e-03 4.8e-02 1.4e-02
8 Liver isoform ratio ENSRNOT00000012948 0.24 0.12 0.0e+00 0.18 0.18 0.18 0.19 2.2e-19 3.4e-19 1.5e-19 2.5e-20
9 Liver isoform ratio ENSRNOT00000081912 0.27 0.13 0.0e+00 0.17 0.17 0.17 0.18 2.5e-18 3.7e-18 1.6e-18 4.0e-19
10 Liver intron excision ratio chr15:36640915:36643646 0.08 0.04 7.4e-11 0.09 0.09 0.09 0.09 1.2e-09 2.3e-10 8.6e-10 6.3e-10
11 Liver mRNA stability ENSRNOG00000009440 0.07 0.04 1.5e-09 0.07 0.08 0.06 0.07 1.2e-08 8.6e-09 1.2e-07 3.4e-08
12 NAcc alternative polyA ENSRNOT00000012948 0.06 0.04 1.9e-04 0.06 0.05 0.08 0.08 4.3e-05 2.2e-04 7.8e-07 2.8e-06
13 NAcc gene expression ENSRNOG00000009440 0.23 0.09 0.0e+00 0.22 0.21 0.21 0.21 1.6e-16 2.1e-15 6.4e-16 1.4e-15
14 PL gene expression ENSRNOG00000009440 0.5 0.14 0.0e+00 0.36 0.35 0.34 0.35 2.9e-28 3.1e-27 6.7e-27 7.3e-28
15 PL mRNA stability ENSRNOG00000009440 0.05 0.04 5.7e-03 0.01 0.02 0.01 0.01 2.3e-02 1.1e-02 6.2e-02 4.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.41.22.2-0.9-1.0-0.91.3-1.4-1.11.11.2-1.5-1.1-0.81.1-1.0-0.9-0.3
BMI without tail0.00.10.20.00.20.1-0.1-0.00.2-0.2-0.1-0.30.30.4-0.10.20.20.5
Body weight0.83.34.0-1.5-1.9-1.91.8-1.9-1.81.91.8-1.5-2.0-1.92.0-2.0-1.9-1.5
Epididymis fat weight0.20.42.50.50.40.3-0.90.70.6-0.5-1.01.60.50.30.10.10.3-0.6
Glucose0.40.61.6-0.8-0.8-0.90.7-0.6-0.70.70.7-1.3-0.8-0.40.6-0.9-1.00.3
Heart weight0.10.20.6-0.1-0.2-0.30.6-0.6-0.50.50.6-0.8-0.5-0.40.2-0.3-0.3-0.1
Left kidney weight2.57.29.3-2.1-2.6-2.62.9-2.7-2.82.83.0-3.0-3.1-2.92.1-2.9-2.7-1.7
Right kidney weight3.610.312.8-2.8-3.0-3.13.5-3.5-3.43.43.6-3.3-3.4-3.52.7-3.0-3.1-2.6
Tail length0.00.10.70.1-0.1-0.3-0.10.2-0.00.0-0.10.6-0.0-0.40.3-0.1-0.3-0.8
Length with tail0.10.51.3-0.2-0.8-0.90.2-0.1-0.50.50.20.5-0.7-0.90.8-0.9-1.0-1.2
Length without tail0.61.42.0-0.7-1.4-1.31.0-1.0-1.21.21.0-0.4-1.4-1.41.3-1.4-1.4-1.2
Liver weight, left4.57.28.9-3.0-2.7-3.02.7-2.7-2.72.72.7-2.5-2.7-2.62.8-2.4-3.0-2.0
Liver weight, right0.10.20.5-0.7-0.4-0.40.5-0.6-0.50.50.4-0.2-0.4-0.40.6-0.3-0.4-0.6
Parametrial fat weight3.16.09.62.12.42.3-2.92.72.6-2.6-2.93.12.62.4-1.82.32.21.2
Retroperitoneal fat weight0.30.92.10.71.11.0-0.80.61.0-1.0-0.91.51.10.8-0.41.11.0-0.1
Intraocular pressure1.82.64.21.51.91.9-1.01.31.7-1.7-1.01.31.71.4-2.02.01.91.0
Extensor digitorum longus weight7.128.633.5-5.6-5.6-5.55.1-5.2-5.65.65.0-3.8-5.6-5.55.8-5.7-5.5-5.0
Soleus weight0.61.83.0-1.4-1.2-1.31.6-1.7-1.41.41.6-1.5-1.1-1.11.6-0.8-1.3-1.1
Tibialis anterior weight7.826.931.9-5.5-5.5-5.35.0-5.1-5.45.44.9-4.4-5.5-5.25.3-5.6-5.4-4.1
Tibia length0.72.04.1-1.7-1.6-1.61.4-1.0-1.21.21.6-2.0-1.6-1.20.6-1.5-1.60.4
Number of licking bursts0.20.20.5-0.4-0.6-0.60.4-0.5-0.50.50.4-0.7-0.4-0.30.6-0.3-0.6-0.1
Food consumed during 24 hour testing period0.20.20.5-0.7-0.4-0.50.6-0.5-0.40.40.6-0.7-0.5-0.50.2-0.4-0.5-0.1
Times rat made contact with spout0.40.51.2-1.1-1.0-1.10.1-0.1-0.50.50.2-0.3-0.7-0.50.6-0.9-1.1-0.0
Mean time between licks in bursts1.01.43.11.11.11.0-0.90.91.3-1.3-0.80.21.31.4-1.31.31.11.7
Mean num. licks in bursts0.00.00.2-0.3-0.1-0.10.00.1-0.10.10.10.1-0.2-0.2-0.1-0.4-0.2-0.1
Std. dev. time between licks in bursts2.22.64.01.81.71.6-1.51.51.7-1.7-1.51.71.81.5-1.62.01.61.0
Water consumed over 24 hours0.50.61.0-0.9-0.9-1.00.6-0.6-0.70.70.7-0.5-0.8-0.80.8-0.6-1.0-0.6
Indifference point 0 sec0.10.10.40.30.00.1-0.40.50.4-0.4-0.40.60.20.3-0.20.20.00.4
Indifference point AUC0.10.10.7-0.5-0.3-0.3-0.1-0.1-0.10.1-0.1-0.80.00.30.2-0.1-0.30.7
Indifference point function ln k0.40.51.3-0.2-0.7-0.50.8-0.7-0.80.80.80.0-0.8-1.00.7-0.7-0.6-1.1
Indifference point function log k0.40.51.3-0.2-0.7-0.50.8-0.7-0.80.80.80.0-0.8-1.00.7-0.7-0.6-1.1
Delay discounting total patch changes 0 sec0.00.10.2-0.1-0.4-0.4-0.00.1-0.10.1-0.10.4-0.3-0.20.3-0.3-0.4-0.1
Delay discounting total patch changes 12 sec0.30.41.2-1.1-0.8-0.80.3-0.4-0.50.50.4-0.9-0.6-0.30.5-0.6-0.80.2
Delay discounting total patch changes 18 sec0.10.10.5-0.7-0.4-0.50.1-0.2-0.30.30.1-0.1-0.2-0.20.7-0.4-0.5-0.3
Delay discounting total patch changes 24 sec0.40.61.3-0.9-1.0-1.10.3-0.2-0.70.70.3-0.1-0.7-0.71.0-0.8-1.1-0.6
Delay discounting total patch changes 6 sec0.10.10.5-0.5-0.3-0.2-0.0-0.00.1-0.1-0.0-0.40.10.30.10.2-0.20.7
Delay discounting time to switch 0 sec0.30.41.20.30.60.6-0.90.90.6-0.6-0.91.10.60.4-0.50.30.7-0.0
Delay discounting water rate 0 sec1.11.82.2-0.9-1.4-1.31.4-1.5-1.41.41.4-1.1-1.4-1.41.4-1.3-1.3-1.1
Delay discounting water rate 12 sec3.55.27.3-1.9-2.2-2.22.3-2.2-2.42.42.3-1.3-2.3-2.72.5-2.4-2.2-2.7
Delay discounting water rate 18 sec7.49.711.0-2.7-3.2-3.23.2-3.2-3.33.33.2-2.6-3.3-3.33.2-3.2-3.2-2.7
Delay discounting water rate 24 sec1.21.73.3-0.9-1.0-1.21.4-1.3-1.31.31.4-0.6-1.2-1.51.4-1.2-1.2-1.8
Delay discounting water rate 6 sec2.73.95.8-1.6-2.0-2.01.9-1.9-2.12.11.8-1.0-2.0-2.32.2-2.0-2.0-2.4
Locomotor activity3.45.47.8-2.2-2.4-2.52.1-2.0-2.42.42.2-1.5-2.6-2.62.2-2.8-2.5-2.2
Locomotor testing distance0.40.71.7-0.7-0.9-1.00.6-0.4-0.70.70.6-0.2-1.0-1.00.7-1.3-1.1-0.8
Locomotor testing rearing0.10.10.4-0.1-0.2-0.10.40.0-0.00.00.5-0.6-0.4-0.3-0.7-0.4-0.10.6
Light reinforcement 10.30.61.0-1.0-1.0-1.00.3-0.2-0.70.70.3-0.2-0.9-0.80.8-0.9-1.0-0.7
Light reinforcement 20.81.12.10.90.91.0-1.21.01.0-1.0-1.31.41.11.0-0.61.11.00.2
Reaction time number correct0.10.10.50.10.10.2-0.30.40.3-0.4-0.2-0.10.30.4-0.50.30.20.7
Reaction time mean minus median0.10.10.5-0.30.10.10.6-0.5-0.30.30.6-0.2-0.2-0.5-0.10.30.2-0.7
Reaction time mean minus median AUC0.10.20.6-0.30.30.30.6-0.5-0.10.10.6-0.8-0.0-0.1-0.50.50.40.1
Reaction time num false alarms0.20.31.0-0.6-0.9-0.90.20.0-0.40.40.2-0.2-0.7-0.50.5-0.8-1.0-0.0
Reaction time num false alarms AUC0.50.71.7-0.9-1.1-1.20.5-0.3-0.70.70.5-0.5-0.9-0.70.8-1.2-1.3-0.2
Reaction time trials correct on left0.10.10.50.10.10.2-0.30.40.3-0.4-0.2-0.10.30.4-0.50.30.20.7
Reaction time trials on left0.10.20.70.20.20.3-0.30.50.4-0.4-0.3-0.10.40.5-0.60.40.20.8
Reaction time mean0.40.61.01.01.00.9-0.60.60.7-0.7-0.60.80.70.4-0.81.00.9-0.0
Reaction time mean AUC0.60.81.31.11.11.0-0.60.70.8-0.8-0.60.90.80.5-1.01.11.10.0
Median of all reaction times0.60.91.71.31.21.0-0.90.90.9-0.9-0.91.10.90.6-0.91.01.10.0
Reaction time omissions1.82.55.01.41.81.8-1.01.11.6-1.6-0.90.11.51.7-2.21.61.92.0
Reaction time false alarm rate0.60.81.6-0.9-1.1-1.20.6-0.5-0.80.80.6-0.5-1.0-0.81.0-1.2-1.3-0.4
Reaction time premature initiation rate0.30.41.3-0.6-0.6-0.80.5-0.4-0.50.60.50.3-0.5-0.80.9-0.5-0.7-1.1
Reaction time premature initiations0.10.10.3-0.3-0.4-0.50.2-0.0-0.20.20.20.3-0.2-0.40.4-0.2-0.4-0.6
Std. dev. reaction times0.30.41.00.60.90.9-0.20.30.5-0.5-0.20.40.60.4-0.91.01.00.1
Reaction time trials completed0.10.20.70.20.20.3-0.30.50.4-0.4-0.3-0.10.40.5-0.60.40.20.8
Reaction time trials AUC0.10.20.60.20.20.3-0.40.60.5-0.5-0.40.10.40.5-0.60.30.20.8
Social response proportion3.23.55.52.31.92.0-1.91.81.9-1.9-1.81.61.91.9-1.91.52.01.6
Social responses1.41.83.31.81.61.4-1.11.11.4-1.4-1.00.81.41.3-1.51.31.51.3
Social time0.50.61.9-0.8-0.9-0.70.6-0.3-0.70.70.7-1.4-1.1-0.7-0.0-1.2-0.70.5
Conditioned locomotion0.91.15.01.10.70.8-1.31.10.7-0.7-1.42.20.80.4-0.10.50.8-0.9
Cocaine response after cond. corrected0.30.31.11.10.70.8-0.40.10.3-0.3-0.50.60.60.5-0.10.40.8-0.2
Cocaine response after cond. not corrected0.20.20.70.80.60.7-0.40.10.3-0.3-0.50.60.50.4-0.10.40.7-0.3
Cocaine response before conditioning0.50.61.1-1.1-0.8-0.80.8-0.6-0.70.70.9-0.8-0.8-0.80.5-0.5-0.8-0.5
Saline control response0.10.20.60.20.50.4-0.20.20.4-0.4-0.20.80.50.1-0.10.70.4-0.6
Condit. Reinf. active minus inactive responses0.50.61.5-0.5-0.4-0.41.2-1.1-0.70.71.2-1.2-0.5-0.70.4-0.1-0.5-0.6
Condit. Reinf. active-inactive response ratio0.80.92.2-0.8-0.8-0.81.3-1.1-0.90.91.3-1.5-0.8-0.80.6-0.5-0.8-0.3
Condit. Reinf. active responses0.71.01.9-0.8-0.7-0.81.4-1.3-1.01.01.4-1.2-0.8-1.00.8-0.4-0.8-1.0
Condit. Reinf. inactive responses0.40.50.90.50.80.8-0.60.50.7-0.7-0.61.00.80.5-0.50.90.8-0.2
Condit. Reinf. lever presses3.44.76.8-2.5-2.1-2.12.5-2.2-2.12.12.6-2.5-2.2-2.21.5-1.9-2.2-1.4
Condit. Reinf. lever reinforcers received1.11.52.9-1.1-0.9-1.01.7-1.6-1.21.21.7-1.5-1.0-1.31.0-0.6-1.0-1.2
Pavlov. Cond. lever latency3.75.06.52.52.32.2-2.52.22.2-2.2-2.52.52.42.3-1.72.12.31.4
Pavlov. Cond. magazine entry latency2.02.23.7-1.4-1.2-1.21.7-1.7-1.61.61.7-1.0-1.5-1.81.4-1.2-1.2-1.9
Pavlov. Cond. change in total contacts4.46.27.0-2.6-2.6-2.62.6-2.4-2.52.52.6-2.2-2.5-2.62.3-2.3-2.6-2.1
Pavlov. Cond. index score4.05.26.8-2.4-2.1-2.12.6-2.4-2.42.42.6-2.2-2.3-2.52.0-1.9-2.1-2.1
Pavlov. Cond. latency score3.94.96.5-2.3-2.0-2.02.5-2.4-2.32.32.6-2.1-2.2-2.41.9-1.9-2.0-2.1
Pavlov. Cond. lever contacts3.24.55.9-2.4-2.1-2.12.3-2.0-2.12.12.3-2.2-2.2-2.31.7-2.1-2.1-1.5
Pavlov. Cond. magazine entry number2.02.43.01.51.41.4-1.71.71.6-1.6-1.71.31.51.7-1.51.31.41.7
Pavlov. Cond. intertrial magazine entries3.03.87.51.31.81.8-1.92.12.1-2.1-1.70.81.92.2-2.51.81.82.7
Pavlov. Cond. lever-magazine prob. diff.3.74.86.3-2.3-2.0-2.02.5-2.4-2.32.32.5-2.1-2.2-2.41.9-1.8-2.0-2.1
Pavlov. Cond. response bias3.95.46.7-2.5-2.2-2.12.6-2.4-2.42.42.6-2.2-2.4-2.52.0-2.1-2.2-2.0
Conditioned reinforcement - actives9.49.313.42.83.63.7-2.62.63.0-3.0-2.62.93.32.9-3.13.63.61.8
Conditioned reinforcement - inactives4.14.66.32.02.01.9-2.32.52.3-2.3-2.32.02.12.2-2.22.01.92.2
Conditioned locomotion3.84.66.82.12.52.5-2.01.82.0-2.0-2.22.62.42.0-1.62.52.50.8
Intermittent access intake day 1-15 change1.31.32.10.91.11.0-1.21.51.3-1.3-1.21.31.21.1-1.30.91.00.7
Intermittent access intake escalation1.61.62.41.01.31.1-1.31.51.5-1.4-1.31.41.41.2-1.31.21.10.8
Intermittent access intake escalation 20.60.60.80.80.70.5-0.70.90.9-0.9-0.60.50.90.8-0.90.70.50.7
Intermitt. access day 1 inactive lever presses5.96.49.82.42.22.1-2.82.82.6-2.6-2.72.02.42.9-2.62.22.23.1
Intermitt. access day 15 inactive lever presses1.61.82.61.51.21.1-1.51.61.4-1.4-1.41.31.21.3-1.51.21.21.4
Intermitt. access escalation Index0.20.20.5-0.5-0.5-0.60.3-0.3-0.30.30.3-0.7-0.4-0.10.4-0.5-0.60.4
Intermittent access day 1 total infusions0.60.61.80.70.80.8-0.90.80.7-0.7-1.01.30.80.8-0.30.70.80.2
Intermittent access day 15 total infusions3.33.75.11.71.91.8-2.12.22.0-2.0-2.12.32.02.0-1.71.81.81.4
Intermittent access terminal intake (last 3 days)2.93.14.71.71.51.4-2.12.21.9-1.9-2.12.21.81.9-1.41.51.41.4
Intermittent access total infusions3.94.35.82.02.12.0-2.22.22.1-2.1-2.32.42.22.2-1.62.12.01.4
Intermittent access day 1 locomotion0.30.31.10.40.50.5-0.70.60.3-0.3-0.81.00.40.4-0.00.40.50.2
Intermittent access day 15 total locomotion2.93.16.11.41.71.5-2.32.21.7-1.7-2.32.51.71.7-1.21.41.40.9
Intermittent access total locomotion1.92.13.61.51.51.3-1.71.61.4-1.3-1.81.91.41.4-1.01.31.40.9
Intermittent access standard deviation1.31.43.21.21.11.0-1.41.61.2-1.2-1.41.81.10.9-1.01.10.90.3
Cocaine induced anxiety0.30.41.1-0.5-0.6-0.40.7-0.6-0.60.60.7-0.2-0.6-0.80.6-0.4-0.4-1.0
Post-drug Anxiety0.00.00.1-0.1-0.2-0.10.10.1-0.00.00.1-0.1-0.2-0.2-0.20.1-0.10.0
Baseline Anxiety0.00.10.10.30.30.2-0.10.20.2-0.2-0.0-0.20.10.2-0.30.20.20.4
Lifetime Intake4.14.56.02.02.32.2-2.12.12.2-2.2-2.22.42.32.2-1.72.22.21.4
Incentive Sensitization - Responses3.13.16.21.32.01.9-1.11.51.8-1.8-1.00.21.71.9-2.51.71.92.5
Incentive Sensitization - Breakpoint2.82.86.01.21.81.7-1.11.51.7-1.8-1.00.21.61.8-2.41.61.82.5
Progressive ratio test 1 active lever presses0.70.71.20.60.70.7-1.11.10.8-0.8-1.11.00.81.0-0.40.60.70.9
Progressive ratio test 1 breakpoint0.70.81.60.70.60.6-1.21.20.8-0.8-1.31.10.81.0-0.30.50.60.9
Progressive ratio test 1 inactive lever presses1.51.62.61.00.91.0-1.61.61.3-1.3-1.61.11.21.4-1.21.01.01.3
Progressive ratio test 2 active lever presses4.34.66.81.72.32.2-1.92.12.2-2.3-1.91.32.22.5-2.42.22.32.6
Progressive ratio test 2 breakpoint3.13.46.11.51.81.8-1.71.81.9-1.9-1.61.01.82.1-2.11.81.82.5
Progressive ratio test 2 inactive lever presses1.92.24.51.01.51.5-1.11.31.5-1.5-1.10.41.41.7-1.91.61.62.1
Total sessions with >9 infusions6.06.57.62.62.72.8-2.42.42.6-2.6-2.42.22.62.7-2.52.72.72.4
Short access day 1 total inactive lever presses0.20.30.40.60.30.3-0.70.50.5-0.5-0.70.60.50.6-0.40.50.30.5
Short access day 10 total inactive lever presses0.10.10.80.10.00.0-0.20.20.1-0.1-0.2-0.60.10.3-0.5-0.00.10.9
Short access day 1 total infusions5.86.17.72.62.52.5-2.62.52.5-2.5-2.72.82.62.6-2.02.52.41.8
Short access day 10 total infusions0.50.52.20.80.70.7-0.80.60.6-0.6-0.91.50.70.5-0.00.70.7-0.2
Short access total infusions2.52.74.71.71.71.7-1.71.61.7-1.6-1.82.21.71.7-1.11.81.70.9
Short access day 1 locomotion2.12.23.21.71.51.5-1.61.41.4-1.4-1.61.81.51.6-1.01.51.51.2
Short access day 10 total locomotion0.00.10.2-0.10.10.10.4-0.4-0.30.30.3-0.1-0.2-0.20.10.10.2-0.2
Short access total locomotion0.30.40.91.00.70.6-0.60.50.4-0.4-0.60.80.50.5-0.30.60.70.5
Compulsive drug intake1.21.23.0-1.1-0.8-0.71.4-1.5-1.11.11.4-1.7-1.0-1.00.6-0.8-0.7-0.7
One hour access (0.3 mA shock)2.22.54.21.32.12.0-1.00.91.5-1.5-1.00.71.81.7-1.82.02.01.4
One hour access (shock baseline)4.95.76.42.32.52.4-2.42.42.5-2.5-2.52.52.52.5-2.22.42.41.7
Number of responses in last shaping day1.41.44.91.60.70.6-1.61.61.1-1.0-1.72.21.00.9-0.40.70.50.1
Context. condit. distance diff. score0.20.30.80.70.50.5-0.60.40.5-0.4-0.70.90.60.5-0.10.40.4-0.2
Locomotion velocity, session 11.51.62.2-1.1-1.1-1.21.5-1.4-1.41.31.5-1.5-1.3-1.41.0-1.1-1.0-1.0
Locomotion distance, session 10.91.21.5-1.0-1.2-1.11.0-0.9-1.21.11.1-1.2-1.2-1.20.9-1.2-1.0-0.7
Locomotion velocity, session 20.40.41.5-0.5-0.9-0.80.1-0.1-0.60.60.1-0.0-0.8-0.70.7-1.2-0.7-0.4
Locomotion distance, session 20.10.10.6-0.3-0.5-0.4-0.30.5-0.10.1-0.2-0.1-0.5-0.2-0.1-0.8-0.50.4
Locomotion velocity, session 30.91.11.9-1.1-1.3-1.30.8-0.7-1.01.00.8-0.8-1.2-1.01.1-1.4-1.3-0.6
Locomotion distance, session 31.31.42.3-1.2-1.4-1.21.0-1.0-1.21.21.0-1.1-1.3-1.11.1-1.5-1.3-0.8
Stereotopy head waving bouts, day 30.91.11.60.70.90.8-1.21.31.2-1.2-1.21.21.11.1-0.91.00.90.8
Stereotopy head waving duration, day 30.10.10.2-0.4-0.4-0.50.3-0.2-0.30.30.3-0.2-0.3-0.30.4-0.3-0.4-0.3
Locomotion velocity, session 70.10.20.70.2-0.10.0-0.60.60.3-0.3-0.60.10.10.5-0.2-0.30.00.8
Locomotion distance, session 71.92.43.51.61.31.3-1.91.91.6-1.6-1.91.51.51.7-1.31.21.31.4
Stereotopy head waving bouts, day 73.23.65.0-2.2-2.0-2.11.8-1.7-1.91.91.8-1.8-2.0-1.91.8-2.0-2.1-1.2
Stereotopy head waving duration, day 74.65.66.7-2.6-2.5-2.52.3-2.3-2.42.42.3-2.1-2.5-2.42.3-2.5-2.5-1.8
Locomotion velocity, session 80.40.51.5-0.3-0.7-0.60.0-0.1-0.70.70.00.4-0.8-0.80.8-1.2-0.7-1.0
Locomotion distance, session 80.10.10.30.0-0.4-0.3-0.20.2-0.20.2-0.20.3-0.3-0.30.3-0.6-0.4-0.4
Degree of sensitization distance7.77.88.82.82.82.7-2.82.82.9-2.9-2.82.42.93.0-2.73.02.82.5
Degree of sensitization stereotypy4.14.55.2-2.3-2.0-2.02.2-2.2-2.22.22.2-1.8-2.2-2.22.1-2.1-2.0-1.9
Condit. Reinf. active minus inactive responses1.82.03.8-1.8-1.3-1.41.7-1.4-1.41.41.8-2.0-1.5-1.40.7-1.2-1.3-0.5
Condit. Reinf. active-inactive response ratio0.10.10.7-0.5-0.1-0.20.4-0.2-0.10.10.4-0.8-0.1-0.0-0.30.1-0.20.5
Condit. Reinf. active responses3.03.75.9-2.1-1.7-1.82.3-2.1-2.01.92.4-2.2-2.0-2.11.3-1.6-1.7-1.4
Condit. Reinf. inactive responses1.82.13.4-1.1-1.2-1.31.6-1.6-1.51.51.6-0.9-1.4-1.81.4-1.2-1.3-1.8
Incentive salience index mean3.64.36.4-2.3-1.9-1.92.4-2.2-2.12.12.5-2.5-2.2-2.21.4-1.8-1.9-1.2
Condit. Reinf. lever presses4.05.48.2-2.2-2.0-2.02.8-2.6-2.52.52.9-2.6-2.4-2.51.8-1.9-2.0-1.7
Time in familiar zone, hab. session 10.30.30.6-0.4-0.2-0.40.7-0.8-0.60.60.7-0.4-0.4-0.50.6-0.3-0.4-0.7
Time in novel zone, hab. session 10.40.40.90.50.20.3-0.91.00.6-0.6-0.90.60.50.7-0.50.30.40.7
Total zone transitions, hab. session 10.60.91.4-0.8-1.2-1.00.8-0.9-1.01.00.8-0.8-1.0-0.91.1-1.0-1.0-0.6
Total locomotion distance, hab. session 10.10.10.4-0.3-0.5-0.6-0.10.0-0.20.2-0.10.1-0.2-0.20.6-0.3-0.6-0.2
Locomotion velocity, hab. session 10.20.30.7-0.5-0.7-0.80.3-0.3-0.40.40.20.0-0.5-0.60.8-0.4-0.8-0.7
Time in familiar zone, hab. session 20.40.41.60.80.70.6-0.50.40.5-0.5-0.61.30.70.3-0.20.70.6-0.6
Time in novel zone, hab. session 20.20.20.8-0.6-0.5-0.40.2-0.1-0.30.20.3-0.9-0.5-0.1-0.0-0.6-0.30.6
Total zone transitions, hab. session 22.22.83.8-1.6-2.0-1.91.3-1.3-1.71.71.3-1.0-1.8-1.81.9-1.9-1.9-1.7
Total locomotion distance, hab. session 21.21.62.8-1.3-1.6-1.60.5-0.6-1.21.20.5-0.2-1.4-1.31.7-1.7-1.6-1.4
Locomotion velocity, hab. session 21.42.03.1-1.4-1.7-1.70.7-0.8-1.41.40.7-0.4-1.5-1.51.8-1.8-1.7-1.4
Novel to familiar place preference ratio1.92.02.71.51.31.4-1.51.61.4-1.4-1.51.31.21.4-1.61.01.51.5
Novelty place preference1.81.92.71.41.31.4-1.51.61.4-1.4-1.41.21.11.3-1.60.81.41.5
Time in novel zone, NPP test1.71.72.71.41.21.3-1.41.61.3-1.3-1.31.21.01.2-1.60.81.41.4
Total zone transitions, NPP test1.11.51.9-1.1-1.4-1.31.1-1.1-1.31.31.1-1.1-1.4-1.31.2-1.3-1.3-1.0
Total locomotion distance, NPP test0.10.10.80.3-0.1-0.1-0.50.60.3-0.3-0.4-0.10.10.3-0.4-0.1-0.00.9
Locomotion velocity, NPP test0.10.10.60.1-0.2-0.3-0.40.50.2-0.2-0.4-0.2-0.00.2-0.2-0.2-0.20.8
Pavlov. Cond. lever latency1.31.63.61.01.00.9-1.71.61.4-1.4-1.71.91.31.2-0.80.80.80.6
Pavlov. Cond. magazine entry latency0.10.20.5-0.10.0-0.00.7-0.6-0.30.30.7-0.7-0.2-0.3-0.00.40.0-0.1
Pavlov. Cond. change in total contacts0.70.81.8-0.6-0.5-0.41.3-1.2-1.01.01.3-1.3-1.0-1.00.4-0.5-0.4-0.4
Pavlov. Cond. index score2.12.75.0-1.3-1.4-1.32.1-2.0-1.81.82.1-2.2-1.8-1.71.1-1.2-1.2-0.8
Pavlov. Cond. latency score1.82.24.8-1.2-1.2-1.12.0-1.9-1.61.62.0-2.2-1.6-1.50.9-1.0-1.0-0.7
Pavlov. Cond. lever contacts1.72.04.2-1.1-1.1-1.01.9-1.8-1.61.61.9-2.0-1.5-1.50.8-1.0-0.9-0.7
Pavlov. Cond. magazine entry number0.81.02.40.80.80.8-1.41.31.1-1.0-1.41.61.01.0-0.60.50.80.4
Pavlov. Cond. intertrial magazine entries1.61.92.3-1.5-1.3-1.41.5-1.4-1.41.41.5-1.0-1.4-1.51.3-1.2-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.2.43.05.5-1.4-1.5-1.42.1-2.1-1.91.92.2-2.3-1.9-1.71.2-1.3-1.3-0.8
Pavlov. Cond. response bias2.42.94.7-1.5-1.4-1.42.1-2.1-1.81.82.2-2.1-1.8-1.81.3-1.2-1.3-1.2
Bone: apparent density0.20.41.10.70.20.1-0.91.10.7-0.7-0.80.70.30.5-0.60.10.10.9
Bone surface0.20.40.90.80.30.3-0.81.00.7-0.7-0.70.70.40.5-0.70.20.30.7
Bone volume0.20.30.80.70.10.1-0.70.90.5-0.5-0.70.60.20.4-0.4-0.00.00.7
Bone: connectivity density0.81.32.21.31.01.0-1.31.51.2-1.2-1.21.31.00.9-1.30.70.91.0
Bone: cortical apparent density0.91.12.1-1.1-0.9-1.11.3-1.4-1.01.01.3-1.5-0.7-0.81.1-0.6-1.0-0.6
Bone: cortical area0.00.00.0-0.2-0.2-0.10.0-0.1-0.20.20.0-0.2-0.20.00.2-0.1-0.20.1
Bone: cortical porosity1.61.74.3-1.5-1.3-1.30.7-0.8-1.31.30.70.3-1.3-1.61.6-1.4-1.3-2.1
Bone: cortical porosity1.51.74.3-1.4-1.3-1.30.8-0.8-1.31.30.80.2-1.3-1.61.5-1.4-1.3-2.1
Bone: cortical thickness0.30.40.7-0.7-0.6-0.60.7-0.8-0.80.80.7-0.7-0.6-0.60.8-0.6-0.6-0.5
Bone: cortical thickness1.11.31.7-1.1-1.1-1.01.1-1.3-1.31.31.0-1.0-1.2-1.11.3-1.3-1.0-1.0
Bone: cortical tissue density0.91.12.2-1.1-0.9-1.01.3-1.4-1.01.01.3-1.5-0.7-0.71.1-0.6-1.0-0.6
Bone: elastic displacement0.40.52.10.90.50.6-0.80.80.5-0.5-0.81.40.50.3-0.50.20.6-0.4
Bone: elastic work0.20.30.6-0.3-0.6-0.70.2-0.1-0.40.40.20.3-0.5-0.60.5-0.7-0.8-0.7
Bone: endosteal estimation0.40.91.71.00.60.7-1.21.31.0-1.0-1.11.00.80.9-0.90.90.61.0
Bone: endosteal perimeter1.02.02.91.61.21.3-1.61.71.4-1.4-1.61.51.31.3-1.51.21.31.0
Bone: final force0.71.22.4-1.4-1.4-1.50.6-0.7-1.01.00.6-0.3-1.1-1.11.5-1.0-1.5-1.0
Bone: final moment1.01.62.9-1.5-1.5-1.60.9-0.8-1.21.20.8-0.5-1.3-1.31.6-1.2-1.7-1.2
Bone: marrow area0.51.01.91.00.60.7-1.31.41.1-1.1-1.21.10.81.0-1.00.90.61.0
Bone: maximum diameter0.61.01.61.10.91.0-1.21.11.0-0.9-1.31.10.91.1-0.80.91.00.7
Bone: maximum force0.61.02.1-1.2-1.2-1.30.4-0.5-0.90.90.40.1-1.0-1.01.5-0.9-1.4-1.1
Bone: maximum moment0.81.42.7-1.4-1.4-1.50.7-0.7-1.11.10.7-0.2-1.2-1.31.6-1.2-1.6-1.3
Bone: minimum diameter0.10.20.50.40.30.4-0.70.70.5-0.5-0.70.60.30.5-0.50.40.20.5
Bone: periosteal estimation0.40.81.21.00.70.8-1.11.10.9-0.9-1.10.80.81.0-0.90.90.71.1
Bone: periosteal perimeter0.40.60.90.90.60.7-0.90.90.7-0.7-0.90.60.60.8-0.90.70.70.8
Bone: post-yield work0.10.20.7-0.6-0.3-0.4-0.20.0-0.20.2-0.30.5-0.1-0.10.8-0.3-0.4-0.8
Bone: stiffness0.20.30.7-0.7-0.8-0.80.1-0.1-0.40.40.0-0.3-0.5-0.30.8-0.5-0.80.1
Bone: tissue strength0.30.30.50.20.40.2-0.60.70.7-0.7-0.50.50.70.6-0.50.70.20.5
Bone: trabecular number0.60.91.71.30.80.9-1.11.31.0-1.0-1.01.00.70.8-1.10.50.80.8
Bone: trabecular spacing0.30.41.1-0.7-0.4-0.40.6-0.8-0.60.70.5-0.2-0.4-0.50.9-0.3-0.4-1.0
Bone: trabecular thickness0.80.91.7-0.7-1.3-1.30.7-0.6-1.01.00.7-0.7-1.2-0.91.0-1.2-1.3-0.4
Bone: trabecular tissue density0.81.11.5-1.2-1.1-1.11.0-1.2-1.11.10.9-1.1-1.0-0.81.2-0.9-1.1-0.6
Breakpoint value in progressive ratio session0.00.00.10.20.0-0.3-0.20.2-0.10.1-0.20.3-0.1-0.10.3-0.2-0.3-0.1
Distance traveled before self-admin0.10.10.4-0.40.30.1-0.00.1-0.00.0-0.00.60.0-0.20.20.10.1-0.6
Distance traveled after self-admin0.60.72.40.70.70.7-0.91.00.7-0.7-1.01.50.80.5-0.30.80.7-0.2
Delta time in closed arm before/after self-admin0.10.10.5-0.10.10.0-0.40.30.3-0.3-0.40.70.20.20.20.10.00.0
Delta time in open arm before/after self-admin4.03.86.72.02.02.1-1.51.51.9-1.9-1.50.41.92.2-2.42.12.12.6
Diff in mean of infusions in LGA sessions0.20.20.80.1-0.3-0.5-0.60.40.1-0.1-0.60.9-0.20.00.5-0.4-0.5-0.0
Extinction: sum of active levers before priming0.20.20.40.20.60.3-0.60.50.4-0.4-0.60.60.50.4-0.20.60.30.2
Active lever presses in extinction session 60.20.20.90.10.1-0.0-0.70.80.3-0.2-0.70.90.20.1-0.10.1-0.0-0.3
Delta distance traveled before/after self-admin1.01.12.11.40.81.0-0.90.91.0-1.0-0.90.61.01.1-1.11.11.01.2
Delta ambulatory time before/after self-admin0.70.81.41.20.60.8-0.90.80.9-0.9-0.90.80.90.9-0.80.90.80.8
Time in closed arm before self-admin1.92.23.0-1.7-1.6-1.61.2-1.2-1.61.61.2-1.0-1.7-1.61.6-1.7-1.6-1.3
Time in closed arm after self-admin3.43.64.8-2.2-1.9-1.91.8-1.7-1.91.91.7-1.1-2.0-2.02.2-2.0-1.9-1.8
Time in open arm before self-admin0.40.52.0-0.6-0.6-0.70.4-0.3-0.50.60.40.4-0.5-0.90.8-0.6-0.7-1.4
Time in open arm after self-admin2.32.64.81.61.41.4-1.51.61.7-1.7-1.50.81.61.9-1.81.51.42.2
Sum of active levers in priming session hrs 5-60.00.00.00.20.0-0.1-0.10.20.0-0.0-0.1-0.20.10.1-0.20.1-0.10.2
Time to tail flick, vehicle, before self-admin0.10.10.5-0.5-0.1-0.00.1-0.0-0.10.10.00.5-0.2-0.40.3-0.1-0.0-0.7
Time to tail flick, vehicle, after self-admin0.20.20.7-0.3-0.6-0.70.2-0.2-0.30.30.20.0-0.4-0.40.7-0.8-0.7-0.6
Time to tail flick, test, before self-admin1.11.11.9-1.4-1.0-1.11.2-0.9-0.90.91.3-1.0-0.9-1.10.9-0.9-1.1-0.8
Time to tail flick, test, after self-admin1.71.72.61.21.61.6-0.91.21.4-1.4-0.90.91.51.2-1.61.51.60.8
Delta time to tail flick, vehicle, before/after SA0.10.10.60.4-0.1-0.2-0.30.30.2-0.2-0.3-0.10.10.4-0.2-0.4-0.20.8
Delta time to tail flick, test, before/after SA2.42.13.41.61.81.9-1.21.21.4-1.4-1.21.01.51.3-1.71.61.90.8
Ambulatory time before self-admin0.60.61.6-1.0-0.6-0.60.7-0.7-0.80.80.7-0.1-0.7-1.01.0-0.6-0.6-1.3
Ambulatory time after self-admin0.30.31.5-0.1-0.3-0.3-0.10.1-0.40.4-0.20.9-0.3-0.60.8-0.3-0.3-1.2
Total heroin consumption0.30.41.1-0.6-0.2-0.21.0-0.8-0.70.71.0-1.0-0.5-0.60.2-0.2-0.1-0.3
Area under the delay curve3.53.75.7-1.8-1.9-1.81.7-2.0-2.12.11.6-1.1-1.9-2.12.3-1.8-1.8-2.4
Delay disc. indifference point, 0s delay0.10.10.4-0.4-0.3-0.30.2-0.3-0.20.30.10.2-0.2-0.30.5-0.3-0.3-0.6
Delay disc. indifference point, 16s delay1.01.03.4-0.5-1.0-0.90.7-1.0-1.11.10.6-0.0-0.9-1.11.6-0.9-0.9-1.8
Delay disc. indifference point, 2s delay1.82.13.0-1.7-1.4-1.41.4-1.5-1.41.51.3-0.8-1.4-1.61.6-1.3-1.4-1.7
Delay disc. indifference point, 24s delay0.70.71.2-0.8-0.7-0.70.8-1.0-1.01.00.7-0.6-0.8-0.91.1-0.7-0.7-1.0
Delay disc. indifference point, 4s delay4.34.56.0-1.9-2.1-2.12.1-2.2-2.22.32.0-1.4-2.2-2.32.4-1.9-2.1-2.4
Delay disc. indifference point, 8s delay2.62.73.9-1.5-1.7-1.61.5-1.7-1.81.81.4-1.1-1.8-1.72.0-1.5-1.6-1.8
Delay discount exponential model param4.64.96.72.22.12.1-2.12.32.4-2.4-2.01.42.32.4-2.62.12.12.5
Delay discount hyperbolic model param4.85.16.92.22.22.2-2.22.42.4-2.4-2.11.52.32.5-2.62.12.22.6
Fecal boli incidents, locomotor time 12.93.13.9-2.0-1.8-1.81.9-1.9-1.81.81.9-2.0-1.8-1.51.7-1.7-1.8-0.8
Change in fecal boli incidents, locomotor task1.81.73.31.50.90.9-1.71.81.4-1.4-1.71.51.11.2-1.20.70.91.0
Time >=10cm from walls, locomotor time 10.10.10.2-0.3-0.2-0.20.3-0.1-0.10.10.30.1-0.3-0.40.1-0.2-0.2-0.4
Bouts of movement, locomotor time 10.60.71.1-0.8-1.0-0.90.7-0.8-0.80.80.7-1.1-1.0-0.70.8-1.0-0.9-0.1
Total resting periods, locomotor time 10.50.61.2-0.7-0.8-0.80.7-0.7-0.70.70.7-1.1-0.9-0.50.8-0.9-0.80.0
Rest time, locomotor task time 13.23.57.9-1.8-1.9-1.92.0-2.0-1.91.92.0-2.8-1.9-1.41.5-1.9-1.9-0.3
Distance moved, locomotor task time 11.82.04.51.41.51.5-1.31.41.4-1.4-1.42.11.51.0-1.11.41.50.0
Vertical activity count, locomotor time 11.71.76.71.51.21.1-1.51.41.2-1.1-1.52.61.20.7-0.60.91.1-0.7
Time >=10cm from walls, locomotor time 20.20.21.00.4-0.0-0.1-0.60.70.3-0.3-0.51.00.2-0.0-0.10.1-0.1-0.3
Bouts of movement, locomotor time 20.10.10.3-0.4-0.4-0.20.2-0.4-0.50.50.2-0.4-0.5-0.20.4-0.4-0.20.0
Total resting periods, locomotor time 20.40.50.8-0.7-0.7-0.60.6-0.8-0.80.80.6-0.9-0.8-0.50.7-0.7-0.60.1
Rest time, locomotor task time 22.73.16.4-1.4-1.8-1.81.9-1.9-1.81.81.9-2.5-1.9-1.41.4-1.9-1.8-0.2
Distance moved, locomotor task time 20.50.52.00.60.80.7-0.60.60.6-0.6-0.61.40.80.2-0.40.90.7-0.8
Vertical activity count, locomotor time 20.91.03.80.81.21.0-0.60.50.7-0.7-0.72.01.00.1-0.21.01.0-1.5
Weight adjusted by age1.41.62.1-1.4-1.3-1.41.3-1.1-1.31.31.3-1.2-1.5-1.30.9-1.4-1.3-0.6
Seeking ratio, delayed vs. immediate footshock1.51.73.31.51.61.8-1.00.91.1-1.1-1.11.81.20.9-1.01.71.80.1
Locomotion in novel chamber1.31.62.0-1.4-1.4-1.41.2-1.1-1.31.31.2-1.1-1.4-1.41.2-1.3-1.4-1.2
Locomotion in novel chamber post-restriction0.10.20.7-0.1-0.2-0.0-0.60.5-0.00.0-0.60.8-0.2-0.20.1-0.5-0.0-0.5
Progressive ratio0.10.10.40.2-0.3-0.30.3-0.2-0.40.40.3-0.0-0.4-0.40.3-0.6-0.2-0.6
Food seeking constrained by brief footshock0.20.30.60.50.80.7-0.40.20.5-0.5-0.40.10.70.7-0.20.70.70.5
Seeking ratio, punishment vs. effort0.00.00.2-0.40.20.1-0.1-0.10.0-0.0-0.1-0.10.20.20.20.4-0.00.1
Run reversals in cocaine runway, females0.90.91.31.01.01.1-0.70.81.0-1.0-0.71.01.00.8-1.01.21.10.4
Run reversals in cocaine runway, males1.21.22.2-1.2-0.8-0.81.5-1.4-1.01.01.5-1.1-0.9-1.11.0-0.6-0.8-1.1
Latency to leave start box in cocaine runway0.70.81.40.90.91.0-0.80.70.9-0.9-0.70.50.81.0-1.20.71.01.0
Latency to leave start box in cocaine runway, F1.61.72.91.51.41.5-1.01.11.3-1.3-1.00.71.21.4-1.71.31.51.6
Latency to leave start box in cocaine runway, M0.20.21.2-0.7-0.4-0.30.5-0.5-0.20.20.6-1.1-0.3-0.1-0.0-0.3-0.30.3
Cd content in liver0.80.92.01.00.90.9-0.70.81.0-1.0-0.70.10.81.0-1.20.90.91.4
Co content in liver0.40.51.2-0.3-0.8-0.80.5-0.6-0.70.70.4-0.0-0.7-0.61.1-0.8-0.8-0.8
Cu content in liver1.11.32.2-1.1-1.4-1.30.9-0.8-1.11.11.0-1.5-1.3-1.00.8-1.4-1.3-0.1
Fe content in liver0.30.30.90.60.50.4-0.60.70.6-0.6-0.50.10.50.6-0.80.50.40.9
K content in liver0.20.21.10.20.0-0.0-0.70.60.5-0.4-0.81.00.50.40.30.2-0.0-0.3
Mg content in liver1.21.22.21.10.80.7-1.41.31.2-1.2-1.41.51.21.2-0.61.00.70.6
Mn content in liver0.91.01.91.00.90.8-1.11.01.1-1.1-1.11.41.21.0-0.51.20.80.3
Na content in liver3.03.14.6-1.9-2.0-2.21.6-1.4-1.71.71.6-1.2-1.9-1.91.9-1.7-2.2-1.6
Rb content in liver4.15.28.02.22.12.0-2.62.62.4-2.4-2.62.82.32.2-1.82.12.01.4
Se content in liver2.83.33.91.91.81.9-2.01.91.8-1.8-2.02.01.71.7-1.81.71.91.3
Sr content in liver0.70.62.60.60.70.7-0.40.50.7-0.7-0.2-0.70.60.8-1.30.60.71.6
Zn content in liver1.01.11.6-1.1-1.2-1.30.7-0.7-1.01.00.8-0.3-1.2-1.21.1-1.2-1.3-1.1