Hub : Genes

Nr1d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000055333 0.04 0.02 9.2e-06 0.02 0.05 0.04 0.04 1.4e-03 3.4e-06 8.9e-05 2.1e-05
2 Adipose alternative polyA ENSRNOT00000117389 0.03 0.02 1.3e-04 0.01 0.04 0.02 0.03 2.0e-02 4.8e-05 1.9e-03 6.9e-04
3 Adipose alternative polyA ENSRNOT00000012537 0.03 0.02 8.4e-05 0.02 0.04 0.02 0.03 3.0e-03 7.8e-05 1.1e-03 5.0e-04
4 Adipose alternative polyA ENSRNOT00000117389 0.03 0.02 8.4e-05 0.01 0.04 0.02 0.03 1.3e-02 2.7e-05 1.0e-03 4.5e-04
5 BLA isoform ratio ENSRNOT00000117389 0.35 0.15 2.3e-04 0.07 0.06 0.05 0.05 1.4e-04 5.6e-04 1.0e-03 1.4e-03
6 Brain isoform ratio ENSRNOT00000117389 0.07 0.04 7.3e-08 0.07 0.08 0.08 0.07 2.4e-07 9.9e-08 1.2e-07 1.6e-07
7 PL alternative polyA ENSRNOT00000055333 0.08 0.06 5.6e-05 0.03 0.04 0.02 0.03 5.0e-03 3.2e-04 5.7e-03 2.6e-03
8 PL alternative polyA ENSRNOT00000117389 0.07 0.05 1.4e-04 0.03 0.04 0.03 0.03 3.5e-03 4.8e-04 3.5e-03 3.2e-03
9 PL alternative polyA ENSRNOT00000012537 0.06 0.06 1.8e-03 0.02 0.02 0 0.02 5.6e-03 7.0e-03 1.7e-01 1.6e-02
10 PL alternative polyA ENSRNOT00000117389 0.05 0.04 3.6e-03 0.02 0.03 0.01 0.02 1.8e-02 4.4e-03 8.5e-02 2.0e-02
11 PL isoform ratio ENSRNOT00000012537 0.07 0.06 8.9e-03 0.03 0.03 0.02 0.03 1.9e-03 3.3e-03 7.0e-03 4.2e-03
12 PL isoform ratio ENSRNOT00000117389 0.07 0.05 4.0e-03 0.01 0.02 0.01 0.01 5.0e-02 1.0e-02 4.4e-02 2.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail2.06.49.6-3.13.1-3.13.1-2.3-2.92.2-2.81.9-2.31.9-0.6
BMI without tail0.10.20.3-0.50.5-0.50.5-0.1-0.50.5-0.50.6-0.40.6-0.2
Body weight4.217.825.8-5.05.1-5.15.1-4.3-4.93.7-4.62.9-3.92.9-1.4
Epididymis fat weight0.00.10.3-0.30.4-0.40.4-0.5-0.40.0-0.20.3-0.10.30.2
Glucose0.10.20.70.0-0.10.0-0.10.80.3-0.30.2-0.50.3-0.50.7
Heart weight3.65.15.9-2.42.4-2.32.4-1.8-2.42.3-2.42.2-2.42.2-1.7
Left kidney weight0.61.83.7-1.51.5-1.51.5-1.9-1.51.3-1.3-0.1-1.3-0.1-1.1
Right kidney weight0.20.51.2-0.60.6-0.70.7-0.9-0.4-0.2-0.2-1.10.1-1.10.7
Tail length0.10.40.7-0.50.6-0.50.6-0.7-0.70.7-0.60.4-0.70.4-0.8
Length with tail1.97.09.4-3.03.0-3.03.0-3.1-3.02.5-2.81.5-2.61.5-1.7
Length without tail2.65.69.0-2.93.0-3.03.0-2.8-2.81.9-2.50.9-2.10.9-0.6
Liver weight, left0.00.10.20.2-0.20.2-0.2-0.20.2-0.30.3-0.50.3-0.50.2
Liver weight, right1.32.16.10.9-1.00.9-0.90.81.2-1.51.4-2.51.4-2.41.3
Parametrial fat weight2.04.05.51.9-1.81.8-1.81.41.9-2.32.1-2.22.3-2.22.1
Retroperitoneal fat weight0.00.10.1-0.40.4-0.40.40.0-0.30.0-0.2-0.3-0.1-0.30.2
Intraocular pressure3.75.28.5-2.12.1-2.12.1-2.0-2.32.3-2.32.9-2.22.9-1.6
Extensor digitorum longus weight8.935.741.3-6.36.3-6.36.3-6.4-6.46.1-6.45.2-6.25.1-4.4
Soleus weight0.10.42.5-0.50.5-0.60.50.4-0.2-0.4-0.2-0.30.4-0.31.6
Tibialis anterior weight1.24.26.5-2.52.5-2.52.5-2.5-2.31.8-2.21.0-1.81.0-0.5
Tibia length1.43.86.9-2.62.6-2.62.6-1.8-2.21.5-2.20.8-1.60.80.2
Number of licking bursts0.20.31.30.2-0.20.2-0.20.40.4-0.70.4-0.50.7-0.51.1
Food consumed during 24 hour testing period0.81.01.2-1.01.0-1.01.0-0.9-1.11.0-1.11.1-1.01.1-0.6
Times rat made contact with spout0.60.70.90.9-0.90.9-0.90.90.9-0.90.8-0.00.9-0.00.8
Mean time between licks in bursts1.52.13.4-1.41.4-1.41.4-1.2-1.61.3-1.51.8-1.31.8-0.8
Mean num. licks in bursts0.10.10.20.4-0.40.5-0.40.40.30.00.20.40.00.4-0.5
Std. dev. time between licks in bursts0.10.10.3-0.20.3-0.30.3-0.6-0.2-0.0-0.1-0.00.0-0.10.3
Water consumed over 24 hours0.20.20.5-0.40.4-0.40.4-0.4-0.40.4-0.50.7-0.40.7-0.2
Indifference point 0 sec1.52.44.22.0-2.02.0-2.02.11.7-1.11.6-0.41.2-0.40.0
Indifference point AUC0.10.10.2-0.20.2-0.20.20.2-0.1-0.1-0.1-0.40.0-0.40.4
Indifference point function ln k0.10.11.00.2-0.20.2-0.2-0.0-0.00.5-0.10.2-0.40.2-1.0
Indifference point function log k0.10.11.00.2-0.20.2-0.2-0.0-0.00.5-0.10.2-0.40.2-1.0
Delay discounting total patch changes 0 sec1.01.73.31.7-1.71.7-1.71.81.4-0.91.3-0.21.0-0.2-0.1
Delay discounting total patch changes 12 sec5.16.88.12.7-2.72.7-2.72.92.8-2.82.8-2.02.8-2.02.2
Delay discounting total patch changes 18 sec0.50.61.00.9-0.90.9-0.91.00.9-0.70.8-0.60.8-0.60.4
Delay discounting total patch changes 24 sec1.72.12.71.4-1.41.4-1.41.51.5-1.41.4-1.61.4-1.61.1
Delay discounting total patch changes 6 sec1.92.94.81.9-1.91.9-1.92.21.8-1.61.8-1.01.6-1.00.9
Delay discounting time to switch 0 sec0.10.10.20.4-0.30.3-0.30.20.3-0.50.4-0.10.5-0.10.5
Delay discounting water rate 0 sec0.00.10.10.3-0.30.3-0.30.20.2-0.10.2-0.10.1-0.1-0.2
Delay discounting water rate 12 sec0.00.10.4-0.10.1-0.10.1-0.7-0.10.1-0.0-0.3-0.2-0.3-0.4
Delay discounting water rate 18 sec0.91.22.70.8-0.80.8-0.80.51.0-1.21.0-1.61.1-1.71.2
Delay discounting water rate 24 sec0.50.71.01.0-1.01.0-1.00.60.9-0.90.9-0.70.9-0.70.5
Delay discounting water rate 6 sec1.92.73.11.7-1.71.7-1.71.61.7-1.71.7-1.81.7-1.71.1
Locomotor activity0.71.22.50.8-0.80.7-0.80.70.9-1.31.0-1.31.3-1.31.6
Locomotor testing distance2.03.33.92.0-2.01.9-2.01.72.0-1.91.9-1.51.9-1.51.4
Locomotor testing rearing5.89.212.03.4-3.53.5-3.43.33.4-2.83.3-2.42.9-2.41.3
Light reinforcement 13.05.46.42.5-2.52.5-2.52.22.5-2.42.5-2.12.4-2.11.5
Light reinforcement 20.70.92.20.6-0.60.6-0.61.10.8-1.10.8-0.81.1-0.91.5
Reaction time number correct0.60.91.4-1.21.1-1.21.1-1.1-1.00.8-1.00.6-0.90.6-0.3
Reaction time mean minus median0.70.92.3-0.60.6-0.60.6-0.9-0.80.9-0.81.5-0.91.5-0.8
Reaction time mean minus median AUC0.20.21.0-0.10.1-0.10.1-0.3-0.20.4-0.41.0-0.41.0-0.4
Reaction time num false alarms0.50.71.90.6-0.60.5-0.61.00.7-1.00.7-0.81.0-0.71.4
Reaction time num false alarms AUC0.30.51.60.5-0.50.4-0.50.70.6-0.90.6-0.50.9-0.41.3
Reaction time trials correct on left0.60.91.4-1.21.1-1.21.1-1.1-1.00.8-1.00.6-0.90.6-0.3
Reaction time trials on left0.60.91.3-1.11.1-1.11.1-1.1-1.00.8-1.00.6-0.90.6-0.3
Reaction time mean0.20.30.60.8-0.80.8-0.8-0.30.6-0.30.6-0.20.3-0.2-0.5
Reaction time mean AUC0.20.30.60.8-0.80.8-0.7-0.40.6-0.30.6-0.40.3-0.4-0.5
Median of all reaction times1.01.32.21.5-1.51.5-1.50.31.3-1.01.3-1.01.0-1.0-0.0
Reaction time omissions1.01.31.61.3-1.31.3-1.30.91.2-1.21.2-0.81.3-0.80.9
Reaction time false alarm rate0.71.01.51.0-0.90.9-1.01.11.0-1.21.0-0.81.2-0.81.2
Reaction time premature initiation rate1.31.85.80.9-0.90.8-0.80.31.1-1.31.1-2.41.2-2.41.2
Reaction time premature initiations0.40.62.7-0.00.0-0.10.0-0.50.2-0.50.3-1.60.4-1.60.7
Std. dev. reaction times0.10.10.50.0-0.00.0-0.0-0.6-0.10.3-0.20.7-0.20.7-0.4
Reaction time trials completed0.60.91.3-1.11.1-1.11.1-1.1-1.00.8-1.00.6-0.90.6-0.3
Reaction time trials AUC0.60.81.1-1.11.0-1.11.0-1.0-1.00.8-1.00.7-0.90.7-0.4
Social response proportion0.30.30.5-0.70.7-0.70.7-0.3-0.60.6-0.70.2-0.60.2-0.2
Social responses0.10.10.7-0.00.0-0.00.00.40.1-0.40.1-0.20.4-0.20.8
Social time0.20.31.0-0.50.5-0.60.5-0.2-0.4-0.1-0.40.60.10.61.0
Conditioned locomotion0.20.30.40.5-0.50.5-0.50.40.5-0.40.5-0.70.4-0.70.0
Cocaine response after cond. corrected1.11.23.60.6-0.60.5-0.61.60.9-1.20.9-1.21.2-1.21.9
Cocaine response after cond. not corrected1.51.64.40.7-0.70.6-0.71.71.1-1.41.0-1.51.4-1.52.1
Cocaine response before conditioning0.10.10.30.3-0.40.4-0.40.20.4-0.20.3-0.50.2-0.50.0
Saline control response0.20.20.5-0.70.6-0.70.6-0.0-0.40.1-0.4-0.1-0.2-0.10.6
Condit. Reinf. active minus inactive responses1.01.21.61.2-1.21.2-1.21.01.1-1.31.2-0.71.3-0.71.0
Condit. Reinf. active-inactive response ratio0.80.91.30.9-0.90.9-0.90.80.9-1.21.0-0.61.2-0.61.1
Condit. Reinf. active responses1.72.33.21.5-1.51.5-1.51.41.5-1.81.6-1.11.8-1.11.6
Condit. Reinf. inactive responses1.92.43.11.5-1.51.4-1.51.71.6-1.81.6-1.31.7-1.31.6
Condit. Reinf. lever presses0.10.20.20.5-0.50.5-0.50.20.4-0.40.5-0.50.4-0.50.0
Condit. Reinf. lever reinforcers received1.72.43.11.6-1.61.6-1.61.41.6-1.81.7-1.21.8-1.21.4
Pavlov. Cond. lever latency0.30.40.5-0.70.7-0.70.7-0.4-0.70.7-0.70.3-0.70.3-0.5
Pavlov. Cond. magazine entry latency0.10.10.4-0.30.3-0.30.3-0.6-0.30.2-0.30.2-0.20.30.1
Pavlov. Cond. change in total contacts0.50.71.21.1-1.11.1-1.11.01.0-0.70.9-0.20.7-0.10.1
Pavlov. Cond. index score0.10.10.20.4-0.40.3-0.40.20.4-0.40.3-0.00.4-0.00.5
Pavlov. Cond. latency score0.00.00.10.2-0.20.2-0.20.10.2-0.30.20.20.20.20.3
Pavlov. Cond. lever contacts0.60.91.21.0-0.90.9-1.00.81.0-1.11.0-0.71.1-0.71.1
Pavlov. Cond. magazine entry number0.00.00.1-0.10.1-0.10.10.0-0.10.2-0.10.2-0.10.1-0.3
Pavlov. Cond. intertrial magazine entries1.62.04.3-1.11.1-1.01.1-1.5-1.41.7-1.31.5-1.61.5-2.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.2-0.20.2-0.20.00.2-0.30.20.10.30.10.3
Pavlov. Cond. response bias1.01.31.81.2-1.21.1-1.21.01.2-1.31.2-1.01.3-1.01.2
Conditioned reinforcement - actives0.50.50.80.9-0.90.9-0.90.60.8-0.50.70.50.50.30.1
Conditioned reinforcement - inactives1.41.62.81.6-1.61.6-1.61.71.3-0.91.3-0.11.00.10.0
Conditioned locomotion0.30.40.70.7-0.70.7-0.70.90.6-0.50.50.60.60.40.4
Intermittent access intake day 1-15 change0.80.82.00.9-0.90.9-0.90.40.9-0.80.9-1.40.8-1.10.4
Intermittent access intake escalation0.90.92.40.9-0.90.9-0.90.40.9-0.90.9-1.60.9-1.30.5
Intermittent access intake escalation 20.10.10.30.1-0.10.1-0.1-0.20.1-0.30.2-0.50.2-0.40.2
Intermitt. access day 1 inactive lever presses3.13.46.31.7-1.71.7-1.61.51.8-1.91.9-2.51.9-2.31.4
Intermitt. access day 15 inactive lever presses4.44.86.32.5-2.52.5-2.52.52.4-2.02.3-2.02.1-1.61.0
Intermitt. access escalation Index1.81.64.7-1.51.5-1.51.5-2.2-1.31.0-1.3-0.0-1.1-0.2-0.3
Intermittent access day 1 total infusions0.20.20.20.4-0.40.4-0.40.50.4-0.50.50.30.5-0.20.4
Intermittent access day 15 total infusions0.91.02.11.0-1.01.0-1.00.71.0-0.91.0-1.20.9-1.50.5
Intermittent access terminal intake (last 3 days)0.80.91.31.0-1.01.0-1.00.91.0-1.01.1-0.81.0-1.20.6
Intermittent access total infusions0.30.30.80.5-0.50.5-0.50.50.6-0.60.6-0.50.6-0.90.3
Intermittent access day 1 locomotion0.20.20.80.5-0.50.5-0.50.90.3-0.10.30.90.20.5-0.1
Intermittent access day 15 total locomotion0.40.41.70.6-0.60.6-0.60.80.4-0.20.31.00.21.3-0.0
Intermittent access total locomotion0.60.61.41.0-1.01.0-1.01.20.8-0.50.80.20.60.3-0.1
Intermittent access standard deviation2.32.43.21.8-1.81.8-1.81.31.6-1.41.7-1.61.4-1.40.4
Cocaine induced anxiety1.41.62.9-1.71.7-1.71.7-1.5-1.40.7-1.30.2-0.80.10.5
Post-drug Anxiety0.20.20.4-0.50.5-0.60.5-0.2-0.30.0-0.3-0.6-0.1-0.50.5
Baseline Anxiety1.01.12.21.3-1.41.4-1.41.51.2-0.51.0-0.40.6-0.1-0.3
Lifetime Intake0.50.51.50.6-0.70.7-0.70.60.7-0.70.8-0.70.7-1.20.4
Incentive Sensitization - Responses1.11.11.71.3-1.31.2-1.31.31.0-0.81.00.90.80.90.2
Incentive Sensitization - Breakpoint1.01.01.71.2-1.21.2-1.21.31.0-0.81.00.80.90.90.3
Progressive ratio test 1 active lever presses0.60.61.00.8-0.80.8-0.81.00.9-0.70.8-0.40.7-0.90.4
Progressive ratio test 1 breakpoint0.50.50.90.7-0.70.7-0.70.90.8-0.60.7-0.50.6-0.90.4
Progressive ratio test 1 inactive lever presses2.02.12.91.5-1.51.6-1.51.51.5-1.31.5-1.61.3-1.70.5
Progressive ratio test 2 active lever presses1.11.22.01.3-1.31.3-1.31.41.2-0.91.20.01.0-0.30.3
Progressive ratio test 2 breakpoint0.80.81.41.1-1.11.1-1.11.21.1-0.81.00.00.8-0.30.2
Progressive ratio test 2 inactive lever presses0.50.51.10.9-0.90.9-0.91.00.8-0.70.80.20.7-0.10.2
Total sessions with >9 infusions0.80.91.81.0-1.01.0-1.01.11.0-0.70.9-1.00.7-1.30.1
Short access day 1 total inactive lever presses2.12.43.01.7-1.71.7-1.71.71.7-1.51.7-0.91.5-1.20.8
Short access day 10 total inactive lever presses0.10.10.5-0.10.1-0.10.2-0.3-0.1-0.1-0.0-0.70.0-0.70.1
Short access day 1 total infusions1.31.43.71.0-1.11.1-1.01.11.1-1.11.2-1.41.0-1.90.4
Short access day 10 total infusions0.40.50.60.6-0.60.6-0.60.70.7-0.80.7-0.40.8-0.80.7
Short access total infusions0.80.93.20.8-0.80.8-0.80.60.9-0.80.9-1.30.8-1.80.3
Short access day 1 locomotion3.84.05.42.2-2.22.2-2.22.32.1-1.92.1-1.62.0-1.61.0
Short access day 10 total locomotion1.01.12.51.2-1.21.2-1.21.61.1-0.91.00.61.00.60.5
Short access total locomotion0.40.41.00.8-0.80.8-0.81.00.6-0.30.60.00.30.1-0.3
Compulsive drug intake0.90.93.3-0.40.4-0.40.4-0.5-0.71.3-0.81.1-1.21.1-1.8
One hour access (0.3 mA shock)0.00.00.30.1-0.10.1-0.1-0.10.10.00.10.5-0.0-0.1-0.2
One hour access (shock baseline)0.50.61.00.6-0.60.6-0.60.60.7-1.00.8-0.60.9-1.01.0
Number of responses in last shaping day0.70.71.10.9-0.90.9-0.91.00.8-0.50.8-0.80.5-1.0-0.2
Context. condit. distance diff. score1.61.94.6-1.11.1-1.01.1-1.5-1.21.8-1.41.1-1.81.1-2.2
Locomotion velocity, session 10.30.30.7-0.80.8-0.80.8-0.4-0.70.3-0.60.2-0.30.10.3
Locomotion distance, session 11.82.33.8-1.91.9-2.01.9-1.3-1.81.2-1.71.0-1.31.0-0.1
Locomotion velocity, session 20.10.10.1-0.30.3-0.30.3-0.2-0.30.1-0.2-0.4-0.2-0.4-0.1
Locomotion distance, session 20.10.21.0-0.50.5-0.60.50.2-0.4-0.3-0.2-0.20.2-0.21.0
Locomotion velocity, session 30.10.10.20.4-0.40.4-0.4-0.10.2-0.10.3-0.30.1-0.3-0.4
Locomotion distance, session 30.20.20.3-0.40.4-0.40.4-0.6-0.50.4-0.40.4-0.40.4-0.3
Stereotopy head waving bouts, day 32.63.13.81.9-1.91.9-1.91.71.9-1.51.8-1.81.6-1.80.8
Stereotopy head waving duration, day 30.20.31.00.4-0.40.4-0.40.40.5-0.40.4-1.00.4-1.00.3
Locomotion velocity, session 71.01.01.7-1.31.3-1.31.3-0.9-1.20.8-1.10.8-0.80.8-0.0
Locomotion distance, session 70.60.81.8-0.90.9-0.90.9-0.3-0.90.8-0.91.3-0.81.4-0.4
Stereotopy head waving bouts, day 70.70.81.60.7-0.70.7-0.70.60.9-0.90.8-1.20.9-1.20.8
Stereotopy head waving duration, day 70.60.72.00.6-0.60.6-0.60.30.7-0.80.7-1.40.8-1.40.8
Locomotion velocity, session 87.08.49.9-3.13.1-3.13.1-3.0-3.13.0-3.12.3-3.12.3-2.2
Locomotion distance, session 81.11.62.1-1.51.5-1.51.5-1.3-1.41.2-1.40.8-1.30.8-0.7
Degree of sensitization distance1.51.62.4-1.21.2-1.21.2-0.7-1.21.3-1.31.5-1.31.5-0.9
Degree of sensitization stereotypy1.01.01.50.9-0.90.9-0.90.81.0-1.11.0-1.21.1-1.21.1
Condit. Reinf. active minus inactive responses0.91.01.71.3-1.31.3-1.31.01.1-0.81.1-0.70.8-0.7-0.1
Condit. Reinf. active-inactive response ratio1.21.22.21.4-1.41.5-1.40.91.3-0.71.2-0.90.8-0.9-0.4
Condit. Reinf. active responses0.91.11.71.3-1.31.3-1.31.01.2-0.91.1-0.80.9-0.80.1
Condit. Reinf. inactive responses0.10.20.60.2-0.20.2-0.20.20.4-0.50.4-0.50.5-0.50.8
Incentive salience index mean1.82.23.11.8-1.71.8-1.71.71.6-1.31.6-0.91.4-0.90.5
Condit. Reinf. lever presses0.91.12.21.1-1.11.1-1.11.51.1-1.11.1-0.61.1-0.60.9
Time in familiar zone, hab. session 10.80.73.40.1-0.10.0-0.10.70.4-1.00.5-1.01.0-1.01.9
Time in novel zone, hab. session 10.70.71.61.0-1.01.1-1.00.70.70.10.50.6-0.00.6-1.3
Total zone transitions, hab. session 11.72.42.8-1.61.6-1.61.6-1.6-1.71.6-1.61.4-1.61.4-1.3
Total locomotion distance, hab. session 10.00.00.30.0-0.00.1-0.0-0.3-0.00.2-0.10.0-0.20.0-0.5
Locomotion velocity, hab. session 10.20.31.0-0.50.5-0.50.5-1.0-0.50.5-0.50.0-0.60.0-0.6
Time in familiar zone, hab. session 21.01.02.30.6-0.60.6-0.60.80.9-1.10.9-1.51.1-1.51.3
Time in novel zone, hab. session 20.20.20.40.6-0.60.6-0.60.30.3-0.00.30.50.10.5-0.6
Total zone transitions, hab. session 21.21.52.2-1.31.3-1.31.3-0.6-1.31.2-1.41.5-1.21.5-0.7
Total locomotion distance, hab. session 20.30.40.8-0.70.7-0.70.7-0.4-0.70.5-0.70.9-0.50.9-0.1
Locomotion velocity, hab. session 20.50.70.9-0.90.9-0.90.9-0.7-0.90.7-0.90.9-0.70.9-0.2
Novel to familiar place preference ratio0.70.72.0-0.80.8-0.80.8-1.4-0.90.9-0.80.1-0.90.1-1.0
Novelty place preference0.70.71.8-0.70.7-0.70.7-1.3-0.81.0-0.70.2-1.00.2-1.2
Time in novel zone, NPP test0.20.20.9-0.30.3-0.30.3-0.9-0.30.6-0.3-0.1-0.6-0.1-0.9
Total zone transitions, NPP test0.71.01.5-1.21.2-1.21.2-0.4-1.10.7-1.11.2-0.71.20.2
Total locomotion distance, NPP test0.10.10.4-0.40.4-0.40.40.2-0.30.1-0.30.6-0.10.60.5
Locomotion velocity, NPP test0.50.71.2-0.90.9-0.90.9-0.5-0.90.7-0.91.1-0.71.1-0.1
Pavlov. Cond. lever latency2.73.45.4-1.71.7-1.61.7-2.1-1.82.2-1.91.4-2.21.5-2.3
Pavlov. Cond. magazine entry latency9.612.414.53.6-3.63.5-3.63.53.7-3.83.7-3.13.8-3.13.1
Pavlov. Cond. change in total contacts8.38.811.43.4-3.43.4-3.33.13.3-2.83.2-2.42.9-2.41.5
Pavlov. Cond. index score7.39.311.53.1-3.13.0-3.13.43.2-3.33.2-2.33.4-2.33.0
Pavlov. Cond. latency score5.67.19.22.6-2.62.5-2.62.92.8-3.02.8-2.13.0-2.12.9
Pavlov. Cond. lever contacts2.02.44.41.4-1.41.4-1.41.71.5-1.91.6-0.91.9-1.02.1
Pavlov. Cond. magazine entry number11.013.816.2-3.93.9-3.93.9-4.0-4.03.8-4.02.9-3.92.9-2.9
Pavlov. Cond. intertrial magazine entries1.31.62.1-1.21.2-1.21.2-1.3-1.31.5-1.31.1-1.51.1-1.4
Pavlov. Cond. lever-magazine prob. diff.8.010.012.33.3-3.33.2-3.33.53.4-3.43.4-2.33.5-2.32.9
Pavlov. Cond. response bias8.410.312.13.4-3.43.4-3.43.43.5-3.33.4-2.63.4-2.62.5
Bone: apparent density2.64.45.32.0-2.02.0-2.01.92.1-2.22.1-2.32.3-2.31.9
Bone surface0.20.41.6-0.00.1-0.10.10.20.2-0.70.3-1.00.6-1.11.3
Bone volume0.40.72.90.2-0.20.2-0.20.50.5-1.00.6-1.11.0-1.11.7
Bone: connectivity density3.85.97.32.4-2.42.4-2.42.12.5-2.52.5-2.72.5-2.71.9
Bone: cortical apparent density4.86.39.93.1-3.13.1-3.12.72.9-2.12.8-1.32.2-1.30.5
Bone: cortical area0.10.10.10.3-0.30.2-0.30.20.3-0.30.3-0.40.3-0.40.2
Bone: cortical porosity0.30.41.40.1-0.10.1-0.20.30.4-0.70.4-0.80.7-0.81.2
Bone: cortical porosity0.30.41.9-0.10.1-0.10.00.20.3-0.70.3-0.90.6-0.91.4
Bone: cortical thickness1.01.62.21.4-1.41.4-1.41.01.5-1.01.3-1.41.1-1.40.3
Bone: cortical thickness6.07.09.72.7-2.82.8-2.72.12.9-2.52.8-3.12.5-3.11.3
Bone: cortical tissue density4.86.39.93.1-3.13.1-3.12.72.9-2.12.8-1.32.2-1.20.6
Bone: elastic displacement0.20.21.00.0-0.00.0-0.0-0.1-0.20.4-0.21.0-0.31.0-0.5
Bone: elastic work0.20.20.60.2-0.20.2-0.2-0.10.3-0.50.4-0.80.5-0.80.6
Bone: endosteal estimation1.83.86.5-2.52.5-2.62.5-1.7-2.31.4-2.11.3-1.51.30.1
Bone: endosteal perimeter1.32.73.4-1.81.8-1.91.8-1.6-1.81.4-1.71.7-1.41.7-0.5
Bone: final force0.91.54.30.6-0.60.5-0.61.11.0-1.41.0-1.71.4-1.72.1
Bone: final moment0.71.13.70.4-0.40.3-0.40.90.8-1.20.8-1.41.2-1.41.9
Bone: marrow area1.73.66.1-2.42.4-2.52.4-1.7-2.21.4-2.01.3-1.51.30.1
Bone: maximum diameter0.10.10.40.1-0.10.1-0.10.20.2-0.40.3-0.30.4-0.30.6
Bone: maximum force0.10.21.1-0.40.4-0.40.40.0-0.1-0.3-0.1-0.70.3-0.71.0
Bone: maximum moment0.10.20.7-0.60.6-0.60.6-0.1-0.3-0.1-0.3-0.40.0-0.40.8
Bone: minimum diameter0.40.71.2-1.11.1-1.11.1-0.7-0.90.6-0.90.3-0.70.30.1
Bone: periosteal estimation0.20.40.9-0.90.9-1.00.9-0.5-0.70.2-0.60.1-0.30.10.6
Bone: periosteal perimeter0.71.11.7-1.31.3-1.31.3-1.1-1.20.7-1.10.8-0.80.80.1
Bone: post-yield work1.41.92.4-1.51.5-1.51.6-1.4-1.51.4-1.51.1-1.41.0-0.9
Bone: stiffness0.20.41.4-0.20.2-0.20.20.10.1-0.50.1-1.20.4-1.21.0
Bone: tissue strength1.51.42.2-1.11.1-1.01.1-1.0-1.21.3-1.31.5-1.31.4-1.0
Bone: trabecular number5.89.010.82.8-2.82.8-2.82.73.1-3.33.1-3.13.3-3.12.9
Bone: trabecular spacing1.72.23.3-1.81.8-1.81.8-1.1-1.71.2-1.61.5-1.31.5-0.1
Bone: trabecular thickness0.10.10.20.4-0.40.4-0.4-0.00.3-0.30.3-0.10.4-0.20.2
Bone: trabecular tissue density0.30.42.60.3-0.30.3-0.30.1-0.00.7-0.10.8-0.60.8-1.6
Breakpoint value in progressive ratio session0.20.20.80.2-0.20.2-0.2-0.20.2-0.50.4-0.90.4-0.60.2
Distance traveled before self-admin0.10.10.3-0.20.2-0.20.2-0.2-0.1-0.30.1-0.10.2-0.40.6
Distance traveled after self-admin1.01.11.6-1.31.3-1.31.3-1.2-1.20.9-1.10.6-0.90.4-0.3
Delta time in closed arm before/after self-admin3.33.24.4-2.12.1-2.12.1-2.0-2.01.7-2.00.7-1.81.1-0.9
Delta time in open arm before/after self-admin0.00.00.1-0.0-0.00.0-0.00.10.00.10.0-0.1-0.1-0.4-0.1
Diff in mean of infusions in LGA sessions0.10.10.50.1-0.10.0-0.1-0.70.0-0.30.2-0.40.2-0.30.1
Extinction: sum of active levers before priming1.41.52.3-1.51.5-1.51.5-1.3-1.41.1-1.40.5-1.10.8-0.2
Active lever presses in extinction session 63.63.58.91.0-1.00.9-1.01.51.4-2.31.7-2.42.2-2.53.0
Delta distance traveled before/after self-admin1.31.41.7-1.31.3-1.21.3-1.3-1.31.3-1.30.8-1.30.7-1.0
Delta ambulatory time before/after self-admin0.91.01.4-1.21.2-1.21.2-1.1-1.11.0-1.20.6-1.00.5-0.4
Time in closed arm before self-admin0.80.91.61.2-1.21.3-1.21.21.1-0.61.0-0.20.7-0.4-0.3
Time in closed arm after self-admin0.50.62.2-0.50.5-0.50.5-0.8-0.61.0-0.70.0-1.00.3-1.5
Time in open arm before self-admin1.31.32.2-1.41.4-1.51.4-1.5-1.30.9-1.20.3-1.00.6-0.3
Time in open arm after self-admin0.40.40.6-0.70.7-0.80.7-0.5-0.70.6-0.70.7-0.60.5-0.3
Sum of active levers in priming session hrs 5-61.01.03.00.5-0.50.5-0.51.00.8-1.00.8-1.41.0-1.71.2
Time to tail flick, vehicle, before self-admin0.50.53.20.00.00.00.00.1-0.20.4-0.31.8-0.31.6-0.4
Time to tail flick, vehicle, after self-admin0.10.10.20.1-0.10.1-0.10.40.1-0.20.10.40.20.50.5
Time to tail flick, test, before self-admin1.61.62.2-1.21.2-1.21.2-1.5-1.31.2-1.31.5-1.21.2-0.8
Time to tail flick, test, after self-admin0.20.21.30.1-0.00.1-0.10.8-0.0-0.1-0.00.80.11.10.4
Delta time to tail flick, vehicle, before/after SA0.60.52.30.3-0.30.2-0.30.60.5-1.00.6-0.90.9-0.61.5
Delta time to tail flick, test, before/after SA1.81.64.81.4-1.41.4-1.42.21.3-1.21.3-0.31.3-0.10.9
Ambulatory time before self-admin0.00.10.3-0.20.2-0.20.2-0.3-0.20.1-0.10.6-0.10.1-0.1
Ambulatory time after self-admin1.71.92.9-1.71.7-1.71.7-1.6-1.61.1-1.51.0-1.20.6-0.3
Total heroin consumption2.12.64.61.5-1.41.4-1.41.31.5-2.11.7-1.12.0-1.22.1
Area under the delay curve0.20.20.40.5-0.50.5-0.50.60.6-0.40.5-0.50.4-0.20.2
Delay disc. indifference point, 0s delay1.11.21.71.1-1.11.1-1.11.31.2-1.11.1-1.11.1-0.80.7
Delay disc. indifference point, 16s delay0.60.62.00.6-0.70.7-0.60.80.8-0.30.6-1.40.3-1.2-0.3
Delay disc. indifference point, 2s delay0.80.91.80.9-0.90.9-0.91.31.1-1.10.9-0.41.1-0.41.2
Delay disc. indifference point, 24s delay0.20.20.5-0.10.1-0.10.10.1-0.20.5-0.30.4-0.50.7-0.7
Delay disc. indifference point, 4s delay1.11.22.60.9-0.90.9-0.90.81.1-1.21.1-1.61.1-1.31.0
Delay disc. indifference point, 8s delay0.10.10.20.3-0.30.3-0.30.40.3-0.10.20.20.20.30.1
Delay discount exponential model param0.10.10.2-0.30.3-0.30.3-0.4-0.40.2-0.30.4-0.20.1-0.1
Delay discount hyperbolic model param0.20.20.3-0.40.5-0.50.5-0.6-0.60.4-0.40.5-0.40.2-0.2
Fecal boli incidents, locomotor time 10.60.62.1-0.70.7-0.70.7-0.1-0.80.8-0.81.0-0.71.5-0.5
Change in fecal boli incidents, locomotor task0.00.00.1-0.20.1-0.20.10.00.00.1-0.10.3-0.1-0.00.1
Time >=10cm from walls, locomotor time 10.20.20.40.5-0.50.5-0.50.70.50.00.30.20.00.1-0.5
Bouts of movement, locomotor time 10.30.31.0-0.60.7-0.70.7-1.0-0.60.3-0.5-0.4-0.3-0.40.1
Total resting periods, locomotor time 10.80.81.6-1.11.1-1.21.1-1.3-1.10.7-1.00.2-0.70.2-0.0
Rest time, locomotor task time 10.00.00.20.00.0-0.00.00.1-0.1-0.2-0.00.10.20.10.4
Distance moved, locomotor task time 10.10.10.30.2-0.20.2-0.20.50.4-0.30.3-0.60.2-0.50.2
Vertical activity count, locomotor time 10.10.10.2-0.40.4-0.40.4-0.1-0.20.3-0.40.4-0.40.1-0.2
Time >=10cm from walls, locomotor time 21.01.11.81.0-1.11.0-1.11.41.2-1.11.1-0.41.1-0.61.0
Bouts of movement, locomotor time 20.50.61.60.7-0.70.7-0.70.20.7-0.60.8-1.20.6-1.30.1
Total resting periods, locomotor time 20.40.41.50.5-0.50.6-0.5-0.00.5-0.40.6-1.20.4-1.2-0.1
Rest time, locomotor task time 20.60.71.1-1.01.0-1.01.0-0.9-1.00.8-1.00.5-0.80.7-0.5
Distance moved, locomotor task time 20.10.10.2-0.40.4-0.40.40.4-0.10.0-0.20.0-0.1-0.20.4
Vertical activity count, locomotor time 20.30.30.5-0.60.6-0.60.6-0.2-0.50.6-0.70.7-0.70.5-0.4
Weight adjusted by age0.30.41.1-0.60.6-0.60.6-0.7-0.3-0.3-0.2-1.10.2-0.71.0
Seeking ratio, delayed vs. immediate footshock0.30.41.30.7-0.70.8-0.70.40.60.10.5-0.2-0.1-0.1-1.1
Locomotion in novel chamber6.07.510.02.7-2.72.6-2.73.22.9-2.82.8-2.82.8-2.52.2
Locomotion in novel chamber post-restriction0.91.12.31.0-1.00.9-1.01.11.0-1.31.0-0.51.3-0.51.5
Progressive ratio0.30.40.90.3-0.30.2-0.30.80.4-0.70.5-0.90.7-0.81.0
Food seeking constrained by brief footshock0.40.51.00.5-0.50.4-0.50.50.6-0.80.6-0.70.8-1.01.0
Seeking ratio, punishment vs. effort0.10.10.4-0.00.1-0.00.1-0.4-0.10.3-0.20.6-0.30.4-0.4
Run reversals in cocaine runway, females2.12.14.0-1.41.4-1.31.4-1.5-1.41.8-1.50.6-1.80.3-2.0
Run reversals in cocaine runway, males0.40.40.80.6-0.70.6-0.70.90.7-0.50.6-0.50.5-0.50.4
Latency to leave start box in cocaine runway1.31.41.8-1.31.3-1.31.3-1.1-1.31.3-1.30.8-1.30.8-1.0
Latency to leave start box in cocaine runway, F1.11.22.0-1.41.4-1.41.4-1.3-1.21.0-1.10.0-1.10.0-0.5
Latency to leave start box in cocaine runway, M0.20.20.50.5-0.50.6-0.50.70.3-0.00.30.50.00.5-0.7
Cd content in liver0.10.20.20.4-0.40.4-0.40.50.4-0.30.4-0.50.3-0.50.2
Co content in liver0.70.81.2-0.70.7-0.70.7-1.1-0.91.0-0.81.0-1.01.0-1.1
Cu content in liver0.00.10.40.2-0.20.2-0.2-0.00.10.10.1-0.0-0.1-0.0-0.7
Fe content in liver0.70.81.4-1.21.2-1.21.2-1.2-1.00.6-0.9-0.0-0.7-0.00.0
K content in liver2.62.65.21.3-1.31.3-1.31.31.5-1.61.6-2.31.6-2.31.3
Mg content in liver1.71.82.91.4-1.51.5-1.51.01.4-1.01.4-1.71.0-1.7-0.1
Mn content in liver2.83.24.02.0-2.02.0-2.01.71.9-1.61.9-1.91.6-1.90.6
Na content in liver1.21.33.70.3-0.30.3-0.30.50.7-1.30.8-1.81.2-1.81.9
Rb content in liver1.31.73.21.5-1.51.5-1.51.81.4-1.11.3-0.81.2-0.80.5
Se content in liver6.27.59.12.9-2.92.9-2.92.42.9-2.73.0-2.72.8-2.71.6
Sr content in liver0.20.10.50.5-0.50.5-0.50.10.30.00.30.30.00.3-0.7
Zn content in liver2.83.14.22.0-2.02.0-2.01.61.9-1.82.0-1.11.8-1.11.0