Hub : Genes

Schip1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009276 0.08 0.06 1.8e-03 0 0.02 0.02 0 2.3e-01 6.2e-03 3.2e-03 8.9e-02
2 BLA mRNA stability ENSRNOG00000009276 0.19 0.13 6.2e-04 0.02 0.04 0.04 0.04 2.2e-02 3.5e-03 3.6e-03 4.4e-03
3 Brain alternative TSS ENSRNOT00000096555 0.04 0.02 1.7e-04 0.03 0.03 0.02 0.03 6.3e-04 2.1e-03 6.6e-03 1.7e-03
4 Brain alternative TSS ENSRNOT00000110983 0.03 0.02 2.9e-03 0.02 0.01 0.01 0.01 6.6e-03 4.5e-02 2.0e-02 2.6e-02
5 Brain isoform ratio ENSRNOT00000057473 0.02 0.02 5.5e-03 0.01 0.01 0.01 0 1.8e-02 3.7e-02 6.4e-02 9.6e-02
6 Brain mRNA stability ENSRNOG00000009276 0.21 0.09 3.9e-16 0.16 0.16 0.15 0.15 1.9e-14 9.5e-15 6.9e-14 3.5e-14
7 LHb alternative TSS ENSRNOT00000057473 0.17 0.11 9.6e-03 -0.01 -0 -0.01 0.01 6.1e-01 3.4e-01 5.3e-01 2.3e-01
8 LHb alternative TSS ENSRNOT00000110983 0.22 0.12 2.1e-03 0.02 0.04 0.02 0.01 1.0e-01 4.1e-02 1.3e-01 1.6e-01
9 LHb alternative TSS ENSRNOT00000057473 0.2 0.11 3.9e-03 0.01 -0.01 -0 0 1.5e-01 4.6e-01 4.2e-01 2.7e-01
10 LHb alternative TSS ENSRNOT00000096555 0.2 0.12 3.4e-03 0.06 0.04 0.05 0.03 1.7e-02 4.3e-02 2.5e-02 6.7e-02
11 LHb alternative TSS ENSRNOT00000110983 0.27 0.13 4.4e-04 0.1 0.06 0.09 0.08 2.6e-03 1.2e-02 3.9e-03 7.2e-03
12 OFC isoform ratio ENSRNOT00000057473 0.3 0.14 3.7e-04 0.12 0.04 0.09 0.07 9.7e-04 4.0e-02 3.3e-03 1.0e-02
13 OFC isoform ratio ENSRNOT00000115543 0.33 0.16 1.1e-03 0 0.03 -0.01 0 3.2e-01 7.3e-02 4.9e-01 2.4e-01
14 PL mRNA stability ENSRNOG00000009276 0.07 0.04 2.5e-04 0.04 0.03 0.03 0.04 1.0e-03 2.8e-03 4.0e-03 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.61.95.9-0.71.12.1-1.4-1.90.62.4-1.12.10.8-0.80.6-0.81.1
BMI without tail0.30.73.10.1-0.60.10.90.1-1.10.30.7-0.1-0.70.71.8-1.2-1.0
Body weight0.51.95.4-0.71.22.1-1.4-1.80.42.3-1.12.21.0-1.00.5-0.60.9
Epididymis fat weight0.81.83.41.8-1.3-1.41.31.3-1.0-1.11.4-1.4-1.41.41.1-0.9-1.7
Glucose0.20.20.80.20.30.6-0.3-0.50.00.9-0.10.5-0.50.50.5-0.90.1
Heart weight0.40.52.6-1.6-0.70.2-0.6-0.1-1.00.40.10.40.2-0.21.3-0.8-0.1
Left kidney weight0.41.32.0-0.5-0.8-1.21.11.2-1.4-1.21.3-1.2-1.31.31.3-1.1-0.8
Right kidney weight0.20.41.10.6-0.4-1.00.91.0-0.4-0.90.5-0.9-0.50.5-0.10.1-0.4
Tail length0.41.23.2-0.2-1.0-0.61.10.8-1.7-0.71.2-0.7-0.90.91.8-1.0-1.5
Length with tail0.20.62.3-1.50.61.0-0.8-0.7-0.10.7-0.51.00.7-0.70.3-0.20.5
Length without tail1.12.54.9-1.61.71.6-2.2-1.51.31.4-1.41.81.5-1.5-1.20.22.1
Liver weight, left0.30.40.70.80.70.8-0.5-0.90.80.8-0.60.80.3-0.3-0.60.20.5
Liver weight, right1.42.34.61.81.91.5-1.6-1.52.21.3-1.31.40.9-0.9-1.80.51.6
Parametrial fat weight0.30.61.6-1.0-0.9-0.11.00.3-1.1-0.20.7-0.1-0.50.51.3-0.9-0.7
Retroperitoneal fat weight0.10.32.61.60.60.10.1-0.00.90.7-0.40.30.0-0.0-0.50.10.1
Intraocular pressure0.40.51.40.1-1.0-0.61.20.8-0.5-0.70.1-0.70.2-0.20.10.8-1.2
Extensor digitorum longus weight3.514.118.20.43.84.1-3.7-4.04.24.0-4.34.04.1-4.1-3.92.73.6
Soleus weight0.51.42.8-1.7-0.6-0.80.80.8-1.4-1.01.4-0.7-1.31.31.5-1.6-0.6
Tibialis anterior weight0.31.01.50.1-0.8-1.11.21.2-1.0-1.01.1-1.1-1.11.10.9-0.6-1.1
Tibia length0.10.31.2-0.8-0.30.4-0.4-0.4-0.10.1-0.60.41.1-1.1-0.30.80.2
Number of licking bursts0.70.83.8-0.51.10.6-0.5-0.7-0.00.40.70.6-1.11.11.0-2.00.8
Food consumed during 24 hour testing period0.50.71.41.2-0.9-1.10.91.1-0.3-0.90.3-1.1-0.40.4-0.30.7-0.9
Times rat made contact with spout1.92.24.10.7-1.1-1.61.21.6-1.3-1.51.7-1.6-2.02.01.1-1.3-1.1
Mean time between licks in bursts5.27.212.40.11.82.5-2.4-2.42.82.7-3.42.63.5-3.5-2.82.72.6
Mean num. licks in bursts1.01.32.41.2-1.5-1.51.11.6-0.6-1.20.3-1.5-0.20.2-0.51.2-1.4
Std. dev. time between licks in bursts5.16.19.8-0.52.42.8-2.7-2.72.53.1-2.92.82.6-2.6-1.71.22.6
Water consumed over 24 hours1.01.23.90.10.2-0.70.50.5-0.8-0.71.4-0.7-1.81.81.3-2.0-0.4
Indifference point 0 sec1.52.56.3-1.2-0.4-1.01.00.9-2.1-1.01.7-1.1-2.02.02.5-2.3-0.9
Indifference point AUC0.91.02.81.70.80.4-0.9-0.71.30.4-1.10.40.9-0.9-1.51.50.6
Indifference point function ln k0.60.93.5-1.9-0.7-0.50.50.5-1.3-0.60.9-0.6-0.80.81.2-1.2-0.4
Indifference point function log k0.60.93.5-1.9-0.7-0.50.50.5-1.3-0.60.9-0.6-0.80.81.2-1.2-0.4
Delay discounting total patch changes 0 sec1.22.04.7-1.2-0.4-1.00.90.8-1.9-0.91.5-1.1-1.81.82.2-2.1-0.7
Delay discounting total patch changes 12 sec0.50.71.41.2-0.2-0.91.00.6-0.6-0.70.8-0.9-1.11.10.6-0.5-0.8
Delay discounting total patch changes 18 sec0.40.51.60.90.3-0.20.10.1-0.5-0.20.6-0.4-1.31.30.9-1.0-0.0
Delay discounting total patch changes 24 sec0.40.52.11.50.8-0.50.00.3-0.1-0.40.6-0.5-1.21.20.4-0.9-0.2
Delay discounting total patch changes 6 sec0.20.20.9-0.30.70.00.1-0.4-0.50.00.3-0.1-0.70.70.7-0.90.2
Delay discounting time to switch 0 sec0.40.61.40.5-0.8-0.51.20.6-0.6-0.20.9-0.4-0.80.80.8-0.8-1.2
Delay discounting water rate 0 sec0.40.61.8-0.70.70.7-1.2-0.70.40.7-0.90.70.6-0.6-0.30.21.3
Delay discounting water rate 12 sec0.60.93.2-1.1-0.2-0.5-0.10.5-1.1-0.61.1-0.4-1.21.21.4-1.80.2
Delay discounting water rate 18 sec0.20.30.8-0.80.80.4-0.4-0.40.40.3-0.50.50.4-0.4-0.40.10.9
Delay discounting water rate 24 sec0.30.41.3-0.40.2-0.4-0.20.4-0.2-0.50.8-0.4-1.11.10.3-1.10.4
Delay discounting water rate 6 sec0.40.62.6-0.40.90.7-1.1-0.70.00.50.40.8-0.60.60.6-1.61.0
Locomotor activity0.50.71.4-0.40.91.0-1.2-1.00.51.1-0.91.10.7-0.7-0.4-0.01.2
Locomotor testing distance1.11.93.2-0.31.51.6-1.8-1.71.21.7-1.51.61.1-1.1-0.90.31.7
Locomotor testing rearing0.40.71.8-0.31.30.9-1.3-0.80.60.8-0.10.9-0.20.20.1-1.21.2
Light reinforcement 10.10.20.80.20.60.40.2-0.20.10.9-0.70.40.6-0.60.10.4-0.3
Light reinforcement 20.91.26.30.1-0.6-0.10.40.10.40.4-1.40.21.8-1.8-1.22.5-0.7
Reaction time number correct3.04.36.4-0.5-1.3-2.11.72.0-2.3-2.12.5-2.0-2.52.52.4-2.4-1.5
Reaction time mean minus median3.34.36.72.11.62.2-1.9-2.12.62.3-2.32.22.2-2.2-1.91.71.3
Reaction time mean minus median AUC6.78.512.32.72.03.1-2.6-3.03.53.3-3.33.13.2-3.2-2.72.62.1
Reaction time num false alarms1.41.98.5-2.00.80.20.2-0.2-1.30.31.20.2-1.51.52.4-2.9-0.1
Reaction time num false alarms AUC1.11.67.7-1.70.70.20.1-0.3-1.10.21.10.2-1.51.52.1-2.8-0.1
Reaction time trials correct on left3.04.36.4-0.5-1.3-2.11.72.0-2.3-2.12.5-2.0-2.52.52.4-2.4-1.5
Reaction time trials on left2.84.06.1-0.5-1.3-2.01.71.9-2.2-1.92.5-1.9-2.42.42.3-2.4-1.5
Reaction time mean2.43.35.21.01.22.3-1.8-2.22.02.0-2.02.12.0-2.0-1.41.41.4
Reaction time mean AUC3.95.37.61.41.72.8-2.2-2.72.62.5-2.52.62.5-2.5-2.01.91.8
Median of all reaction times1.62.13.50.40.81.9-1.5-1.91.41.6-1.51.71.7-1.7-1.11.21.2
Reaction time omissions3.85.18.9-0.10.92.8-1.9-2.71.82.9-2.72.83.0-3.0-1.21.71.7
Reaction time false alarm rate0.60.82.0-1.21.31.1-0.6-1.10.01.2-0.11.1-0.20.20.9-1.40.5
Reaction time premature initiation rate0.30.40.90.60.6-0.5-0.00.40.5-0.70.8-0.5-0.90.9-0.4-0.80.3
Reaction time premature initiations1.31.84.20.2-0.1-1.40.81.3-0.7-1.51.9-1.3-2.02.00.8-2.0-0.4
Std. dev. reaction times4.76.59.71.32.33.1-2.8-3.03.02.8-2.53.02.5-2.5-2.21.52.3
Reaction time trials completed2.84.06.1-0.5-1.3-2.01.71.9-2.2-1.92.5-1.9-2.42.42.3-2.4-1.5
Reaction time trials AUC2.83.95.9-0.7-1.4-1.91.71.9-2.3-1.92.4-1.8-2.32.32.4-2.3-1.5
Social response proportion0.20.22.0-1.4-0.20.3-0.2-0.1-0.40.2-0.20.40.3-0.30.5-0.00.2
Social responses0.30.42.3-0.10.70.2-0.0-0.1-0.20.10.70.3-1.01.00.5-1.50.3
Social time0.10.10.4-0.3-0.3-0.00.70.3-0.40.00.20.1-0.10.10.3-0.1-0.6
Conditioned locomotion0.30.31.0-1.00.30.7-0.6-0.8-0.10.7-0.30.70.3-0.30.5-0.50.6
Cocaine response after cond. corrected0.50.62.4-1.0-1.6-0.71.00.6-0.9-0.2-0.0-0.60.3-0.30.50.6-0.9
Cocaine response after cond. not corrected0.20.30.6-0.8-0.50.2-0.1-0.20.10.6-0.70.20.8-0.8-0.30.70.2
Cocaine response before conditioning0.81.03.10.91.80.9-1.4-0.91.30.8-0.40.9-0.30.3-0.9-0.61.5
Saline control response1.52.04.8-0.22.21.7-2.2-1.71.11.7-0.61.6-0.10.10.0-1.52.0
Condit. Reinf. active minus inactive responses0.81.03.01.21.70.9-1.0-1.01.51.1-0.60.9-0.10.1-0.9-0.31.1
Condit. Reinf. active-inactive response ratio0.20.21.71.30.3-0.20.10.10.40.10.1-0.2-0.70.7-0.1-0.30.0
Condit. Reinf. active responses1.11.54.60.22.11.3-1.6-1.31.61.2-0.81.30.3-0.3-1.2-0.31.7
Condit. Reinf. inactive responses0.81.02.2-1.31.31.2-1.5-1.10.70.8-0.61.20.7-0.7-0.6-0.31.2
Condit. Reinf. lever presses3.65.07.90.82.52.2-2.4-2.32.82.2-2.52.12.0-2.0-2.61.42.7
Condit. Reinf. lever reinforcers received0.81.23.80.11.91.1-1.4-1.11.41.0-0.71.10.3-0.3-1.0-0.41.5
Pavlov. Cond. lever latency1.92.63.7-0.4-1.7-1.61.61.7-1.9-1.71.8-1.6-1.61.61.7-1.1-1.7
Pavlov. Cond. magazine entry latency0.40.41.9-0.70.90.5-0.5-0.60.00.20.40.5-0.60.60.7-1.40.6
Pavlov. Cond. change in total contacts1.41.92.7-0.41.51.5-1.5-1.61.61.6-1.51.51.3-1.3-1.20.61.6
Pavlov. Cond. index score1.31.73.1-0.21.81.5-1.5-1.61.41.4-1.21.51.0-1.0-0.90.11.7
Pavlov. Cond. latency score1.21.52.7-0.41.71.5-1.4-1.61.21.4-1.01.50.8-0.8-0.7-0.11.6
Pavlov. Cond. lever contacts1.21.72.80.51.31.2-1.2-1.31.71.2-1.61.21.4-1.4-1.61.21.4
Pavlov. Cond. magazine entry number0.10.20.80.0-0.7-0.30.30.4-0.2-0.2-0.3-0.30.4-0.4-0.40.9-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.60.1-0.6-0.2-0.00.2-0.2-0.1-0.3-0.20.4-0.4-0.20.8-0.3
Pavlov. Cond. lever-magazine prob. diff.0.91.22.1-0.11.41.3-1.2-1.41.21.2-1.01.30.9-0.9-0.80.21.3
Pavlov. Cond. response bias1.01.42.30.21.41.2-1.1-1.31.51.2-1.31.21.1-1.1-1.20.71.3
Conditioned reinforcement - actives0.10.10.40.60.1-0.10.20.30.2-0.3-0.0-0.3-0.10.1-0.40.30.0
Conditioned reinforcement - inactives0.60.71.4-0.20.20.9-0.9-0.80.61.0-1.10.91.2-1.2-0.61.00.3
Conditioned locomotion0.91.02.0-0.6-0.1-0.81.01.1-1.3-0.80.9-1.0-1.11.11.4-0.8-1.4
Intermittent access intake day 1-15 change0.30.31.5-1.2-0.20.8-0.2-0.4-0.10.7-0.30.70.5-0.50.2-0.10.2
Intermittent access intake escalation0.50.51.7-1.3-0.11.0-0.4-0.70.30.8-0.60.90.9-0.9-0.30.40.4
Intermittent access intake escalation 20.00.00.2-0.1-0.40.10.10.10.00.1-0.00.10.1-0.1-0.10.30.1
Intermitt. access day 1 inactive lever presses1.71.95.01.40.50.6-0.9-1.01.50.8-1.70.71.6-1.6-2.12.20.8
Intermitt. access day 15 inactive lever presses2.42.66.2-0.50.10.7-1.7-0.91.40.7-2.00.72.1-2.1-2.52.52.0
Intermitt. access escalation Index1.11.03.8-0.9-0.30.3-0.10.00.60.1-1.10.21.6-1.6-1.52.00.3
Intermittent access day 1 total infusions0.40.40.70.60.50.8-0.7-0.50.70.8-0.80.80.6-0.6-0.40.40.6
Intermittent access day 15 total infusions0.60.71.20.10.21.1-0.5-0.60.81.0-1.01.01.1-1.1-0.70.90.4
Intermittent access terminal intake (last 3 days)0.60.71.00.60.50.9-0.7-0.51.00.8-1.00.80.9-0.9-1.00.90.9
Intermittent access total infusions0.50.51.0-0.00.30.9-0.6-0.30.70.7-0.90.81.0-1.0-0.70.90.6
Intermittent access day 1 locomotion0.10.10.40.60.30.2-0.30.10.40.3-0.40.20.2-0.2-0.30.40.2
Intermittent access day 15 total locomotion0.10.10.20.40.20.20.30.50.00.30.10.1-0.10.10.4-0.3-0.4
Intermittent access total locomotion0.10.10.3-0.20.50.3-0.10.30.20.4-0.30.30.1-0.10.2-0.10.2
Intermittent access standard deviation1.71.84.10.8-1.5-1.81.52.0-1.0-1.51.2-1.8-1.31.30.5-0.0-1.1
Cocaine induced anxiety1.72.03.40.1-0.9-1.71.41.8-1.1-1.71.6-1.6-1.81.80.8-1.0-1.0
Post-drug Anxiety0.30.31.21.1-1.0-0.50.50.8-0.2-0.50.1-0.4-0.00.0-0.50.8-0.4
Baseline Anxiety4.95.27.51.11.52.5-2.2-2.52.22.4-2.72.52.7-2.7-2.02.11.9
Lifetime Intake0.30.30.6-0.30.10.7-0.6-0.50.40.6-0.60.70.7-0.7-0.40.50.6
Incentive Sensitization - Responses1.11.13.7-0.50.81.7-0.6-0.90.51.9-0.91.71.1-1.10.4-0.3-0.0
Incentive Sensitization - Breakpoint1.01.03.3-0.50.71.6-0.5-0.80.41.8-0.81.61.1-1.10.4-0.2-0.0
Progressive ratio test 1 active lever presses0.10.10.1-0.30.20.3-0.1-0.2-0.00.3-0.20.30.4-0.40.2-0.0-0.1
Progressive ratio test 1 breakpoint0.10.10.2-0.20.30.4-0.4-0.30.20.4-0.40.40.5-0.5-0.20.10.2
Progressive ratio test 1 inactive lever presses0.70.81.90.50.00.8-0.5-0.90.40.9-1.10.91.3-1.3-0.51.4-0.0
Progressive ratio test 2 active lever presses0.40.51.90.10.51.0-0.2-0.50.31.4-0.61.10.8-0.80.4-0.1-0.3
Progressive ratio test 2 breakpoint0.60.62.30.20.71.2-0.4-0.50.61.5-0.71.30.8-0.80.3-0.30.1
Progressive ratio test 2 inactive lever presses0.10.10.30.5-0.0-0.20.40.4-0.10.0-0.2-0.10.1-0.1-0.10.4-0.6
Total sessions with >9 infusions0.40.41.4-1.20.00.8-0.7-0.9-0.40.7-0.30.90.3-0.30.6-0.30.2
Short access day 1 total inactive lever presses0.30.30.8-0.20.90.7-0.4-0.50.60.5-0.70.60.4-0.4-0.70.70.3
Short access day 10 total inactive lever presses0.10.10.40.30.40.3-0.5-0.60.30.5-0.30.40.2-0.2-0.20.20.1
Short access day 1 total infusions0.10.10.6-0.3-0.6-0.1-0.1-0.2-0.1-0.3-0.2-0.20.3-0.3-0.50.7-0.0
Short access day 10 total infusions0.40.41.1-1.0-0.10.6-0.7-0.50.20.3-0.70.60.9-0.9-0.50.60.8
Short access total infusions0.40.51.0-0.60.30.9-1.0-0.90.40.7-0.60.90.7-0.7-0.40.10.9
Short access day 1 locomotion0.20.20.7-0.60.50.2-0.5-0.10.0-0.10.3-0.0-0.50.50.2-0.80.6
Short access day 10 total locomotion1.31.42.51.2-0.7-1.51.21.6-0.7-1.51.3-1.6-1.41.40.5-0.6-0.8
Short access total locomotion0.00.00.20.10.10.0-0.10.10.0-0.10.3-0.1-0.20.20.2-0.50.1
Compulsive drug intake0.40.41.9-0.70.8-0.00.30.4-0.30.30.40.1-0.50.51.0-1.4-0.2
One hour access (0.3 mA shock)0.10.10.6-0.3-0.2-0.00.60.4-0.30.2-0.1-0.00.3-0.30.50.1-0.8
One hour access (shock baseline)0.10.10.70.2-0.7-0.10.2-0.0-0.1-0.1-0.2-0.10.4-0.4-0.30.8-0.4
Number of responses in last shaping day0.40.41.01.0-0.9-0.70.71.0-0.3-0.50.3-0.7-0.30.30.00.4-0.7
Context. condit. distance diff. score3.44.27.20.5-1.2-2.12.22.0-1.8-2.02.4-2.1-2.72.72.0-1.9-2.0
Locomotion velocity, session 10.20.21.31.10.0-0.50.40.50.3-0.4-0.0-0.4-0.10.1-0.70.5-0.1
Locomotion distance, session 11.11.53.70.51.20.9-0.9-0.91.60.7-1.40.91.4-1.4-1.91.41.1
Locomotion velocity, session 20.00.00.10.10.40.0-0.0-0.10.1-0.20.10.10.1-0.1-0.2-0.10.2
Locomotion distance, session 21.92.74.9-0.51.31.5-1.6-1.51.61.3-1.91.52.2-2.2-1.91.61.7
Locomotion velocity, session 30.81.02.7-1.21.60.9-1.2-1.00.70.9-0.31.0-0.10.10.0-1.11.6
Locomotion distance, session 31.41.55.7-1.70.2-0.50.20.5-1.1-0.41.3-0.4-1.71.71.6-2.40.3
Stereotopy head waving bouts, day 30.30.41.40.40.4-0.30.20.2-0.2-0.40.8-0.3-1.11.10.5-1.2-0.2
Stereotopy head waving duration, day 30.40.51.90.10.4-0.10.20.1-0.4-0.30.9-0.1-1.11.10.8-1.4-0.4
Locomotion velocity, session 70.50.62.30.20.30.0-0.0-0.10.8-0.0-0.80.11.0-1.0-1.51.40.4
Locomotion distance, session 70.81.02.20.7-1.2-1.51.21.4-0.4-1.40.5-1.5-0.30.3-0.40.9-1.1
Stereotopy head waving bouts, day 70.50.61.40.41.20.9-0.6-0.81.10.6-0.60.90.6-0.6-0.90.30.7
Stereotopy head waving duration, day 72.12.54.4-0.02.12.0-1.6-2.01.81.8-1.52.01.3-1.3-1.20.41.6
Locomotion velocity, session 80.40.50.90.11.00.8-0.6-0.90.90.8-0.70.80.5-0.5-0.60.20.6
Locomotion distance, session 80.10.20.7-0.10.50.1-0.3-0.10.60.1-0.50.10.5-0.5-0.90.60.6
Degree of sensitization distance2.12.19.42.4-1.2-0.70.90.80.8-0.6-0.9-0.81.3-1.3-1.93.1-1.1
Degree of sensitization stereotypy1.11.22.00.71.21.0-0.7-1.01.40.8-1.11.01.2-1.2-1.41.10.9
Condit. Reinf. active minus inactive responses3.13.54.9-0.91.52.0-1.9-2.11.82.1-2.22.02.1-2.1-1.61.42.0
Condit. Reinf. active-inactive response ratio3.33.65.0-0.61.62.0-1.8-2.02.01.9-2.22.02.2-2.2-1.91.61.8
Condit. Reinf. active responses4.55.57.7-1.11.92.6-2.4-2.72.32.7-2.82.52.6-2.6-1.91.62.5
Condit. Reinf. inactive responses0.50.61.20.30.30.7-0.8-0.80.81.1-1.10.70.8-0.8-0.60.80.7
Incentive salience index mean2.42.94.6-0.61.11.6-1.6-1.71.81.6-2.11.62.1-2.1-1.91.81.7
Condit. Reinf. lever presses1.21.64.50.70.50.6-0.9-0.71.50.5-1.50.61.6-1.6-2.12.10.9
Time in familiar zone, hab. session 11.51.52.30.9-0.8-1.41.31.4-0.9-1.41.4-1.4-1.51.50.7-0.8-1.1
Time in novel zone, hab. session 10.70.73.7-1.90.40.9-0.7-0.9-0.20.9-0.40.90.4-0.40.8-0.70.7
Total zone transitions, hab. session 11.41.92.9-0.21.21.6-1.1-1.61.41.6-1.71.61.6-1.6-1.21.01.2
Total locomotion distance, hab. session 11.11.53.6-0.30.41.0-0.8-1.01.00.9-1.60.91.9-1.9-1.41.80.7
Locomotion velocity, hab. session 11.72.56.70.20.51.0-1.0-1.01.51.0-2.01.02.4-2.4-2.12.60.8
Time in familiar zone, hab. session 26.46.610.51.3-1.5-2.92.62.8-2.1-3.13.2-2.8-3.23.21.9-2.1-2.2
Time in novel zone, hab. session 23.94.07.0-2.41.22.5-2.1-2.41.02.6-2.12.52.2-2.2-0.40.61.7
Total zone transitions, hab. session 21.41.84.20.91.31.1-1.0-1.11.70.9-1.51.11.6-1.6-2.01.51.1
Total locomotion distance, hab. session 21.41.93.90.80.70.9-1.0-1.01.61.0-1.80.91.8-1.8-2.02.00.8
Locomotion velocity, hab. session 21.72.45.60.90.71.0-1.1-1.01.71.0-1.91.02.1-2.1-2.22.40.8
Novel to familiar place preference ratio1.41.52.9-1.70.91.3-1.7-1.30.61.1-1.21.31.4-1.4-0.70.51.4
Novelty place preference1.21.33.6-1.90.81.1-1.5-1.10.50.9-1.01.11.3-1.3-0.50.31.4
Time in novel zone, NPP test1.21.24.8-2.20.81.1-1.5-1.10.20.8-0.81.11.1-1.1-0.2-0.11.3
Total zone transitions, NPP test1.82.66.00.91.21.0-1.1-1.11.90.9-1.91.02.1-2.1-2.42.21.1
Total locomotion distance, NPP test1.21.75.1-0.10.40.7-0.7-0.71.20.5-1.60.72.1-2.1-1.92.20.6
Locomotion velocity, NPP test1.62.27.30.50.40.6-0.7-0.71.40.5-1.80.62.3-2.3-2.42.70.5
Pavlov. Cond. lever latency0.60.82.0-0.7-0.8-0.60.90.7-1.3-0.50.9-0.6-0.80.81.4-0.9-1.0
Pavlov. Cond. magazine entry latency0.10.10.3-0.3-0.2-0.10.20.1-0.3-0.10.4-0.1-0.50.50.5-0.6-0.0
Pavlov. Cond. change in total contacts0.60.62.51.5-0.7-0.40.30.40.5-0.3-0.5-0.40.6-0.6-1.01.6-0.4
Pavlov. Cond. index score0.10.10.40.6-0.1-0.20.10.20.1-0.30.2-0.3-0.20.2-0.20.10.0
Pavlov. Cond. latency score0.10.10.60.8-0.2-0.30.10.20.1-0.30.2-0.3-0.20.2-0.20.20.0
Pavlov. Cond. lever contacts0.60.71.50.30.60.6-0.9-0.61.10.4-0.90.61.0-1.0-1.21.01.0
Pavlov. Cond. magazine entry number0.10.20.6-0.2-0.20.0-0.1-0.00.10.2-0.60.10.7-0.7-0.40.80.1
Pavlov. Cond. intertrial magazine entries1.92.26.1-1.4-0.40.9-1.0-1.00.71.0-2.00.92.5-2.5-1.32.30.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.7-0.2-0.30.10.20.1-0.30.2-0.3-0.30.3-0.10.10.1
Pavlov. Cond. response bias0.20.30.70.40.70.5-0.6-0.50.90.3-0.40.50.4-0.4-0.80.30.7
Bone: apparent density5.08.327.4-1.9-0.2-1.51.21.5-2.7-1.63.6-1.5-4.34.34.0-5.2-1.0
Bone surface1.62.713.9-1.51.30.5-0.6-0.5-0.80.31.60.5-2.32.32.3-3.70.5
Bone volume2.94.920.9-2.20.6-0.40.30.5-1.9-0.72.6-0.5-3.23.23.2-4.6-0.1
Bone: connectivity density2.74.215.7-1.20.1-0.70.70.8-1.8-0.72.5-0.7-3.23.23.0-4.0-0.7
Bone: cortical apparent density5.36.912.3-0.4-3.5-3.12.83.1-3.2-2.92.5-3.1-1.91.92.3-0.7-3.0
Bone: cortical area0.91.46.2-0.41.61.1-0.8-1.0-0.10.90.61.1-1.11.11.5-2.50.5
Bone: cortical porosity3.53.86.1-0.61.51.9-1.8-1.92.01.8-2.22.02.5-2.5-2.11.71.9
Bone: cortical porosity3.13.44.4-0.91.72.1-1.9-2.11.81.9-2.02.12.1-2.1-1.51.11.9
Bone: cortical thickness0.71.24.5-0.10.2-0.20.40.3-1.0-0.31.4-0.2-1.51.51.8-2.1-0.8
Bone: cortical thickness1.41.68.2-0.61.10.3-0.3-0.3-0.60.31.20.3-1.91.91.8-2.90.2
Bone: cortical tissue density5.47.012.7-0.4-3.6-3.12.93.1-3.2-2.92.5-3.2-1.91.92.3-0.6-3.0
Bone: elastic displacement0.20.21.1-0.30.60.3-0.5-0.3-0.10.00.40.2-0.50.50.4-1.10.4
Bone: elastic work0.81.03.8-0.61.80.9-0.9-0.90.30.50.40.9-0.80.80.4-2.01.0
Bone: endosteal estimation0.91.94.5-0.72.11.7-1.9-1.71.11.7-0.81.70.2-0.2-0.1-1.21.9
Bone: endosteal perimeter0.91.85.1-0.12.31.7-1.5-1.81.11.6-0.51.7-0.20.20.0-1.41.7
Bone: final force0.91.46.7-0.62.01.0-0.9-0.90.10.80.61.0-1.11.11.1-2.60.7
Bone: final moment0.81.47.0-0.52.00.8-0.8-0.80.10.60.80.8-1.31.31.0-2.60.6
Bone: marrow area0.91.84.6-0.62.11.6-1.9-1.71.11.6-0.71.60.1-0.1-0.1-1.21.8
Bone: maximum diameter0.71.26.1-0.10.80.3-0.1-0.3-0.60.21.20.3-1.71.71.6-2.5-0.0
Bone: maximum force0.91.55.0-0.52.21.5-1.4-1.40.71.3-0.11.4-0.50.50.4-1.91.2
Bone: maximum moment0.71.34.5-0.52.11.2-1.2-1.20.61.00.11.2-0.60.60.3-1.91.1
Bone: minimum diameter2.03.77.6-1.22.82.6-2.4-2.51.32.5-1.12.50.4-0.40.3-1.72.2
Bone: periosteal estimation1.12.15.3-0.82.31.8-1.9-1.80.71.7-0.31.8-0.40.40.7-2.01.6
Bone: periosteal perimeter0.81.35.5-0.31.81.1-0.9-1.20.20.90.51.1-1.11.11.1-2.30.9
Bone: post-yield work2.43.24.80.81.91.9-1.9-1.82.21.9-2.11.81.7-1.7-1.91.31.7
Bone: stiffness0.10.20.5-0.70.60.5-0.3-0.50.00.5-0.10.50.0-0.00.2-0.60.2
Bone: tissue strength0.10.10.5-0.1-0.2-0.1-0.20.10.0-0.2-0.4-0.10.6-0.6-0.50.7-0.1
Bone: trabecular number6.610.334.0-2.3-0.4-1.51.31.5-3.2-1.64.0-1.5-4.74.74.7-5.8-1.2
Bone: trabecular spacing4.65.919.11.50.51.0-1.0-1.02.60.9-2.91.03.5-3.5-3.94.41.2
Bone: trabecular thickness10.312.523.4-2.2-1.9-2.82.62.8-4.0-2.84.4-2.8-4.54.54.8-4.8-2.5
Bone: trabecular tissue density0.50.72.7-0.4-1.6-0.80.80.9-0.8-0.6-0.2-0.80.7-0.70.11.3-0.9
Breakpoint value in progressive ratio session0.20.30.9-0.50.4-0.20.00.20.60.0-0.60.10.6-0.6-0.90.90.4
Distance traveled before self-admin0.50.51.41.2-0.8-0.81.00.6-0.2-0.80.4-0.8-0.10.1-0.10.7-1.1
Distance traveled after self-admin1.01.12.31.2-1.0-1.41.01.0-0.5-1.50.8-1.4-0.80.8-0.10.7-1.3
Delta time in closed arm before/after self-admin0.80.84.3-2.1-0.20.5-0.7-0.5-0.80.40.50.6-0.40.41.1-1.60.4
Delta time in open arm before/after self-admin0.30.30.80.70.80.1-0.00.10.80.2-0.60.20.6-0.6-0.90.70.2
Diff in mean of infusions in LGA sessions0.70.82.8-1.71.30.8-0.5-0.90.50.9-0.90.90.8-0.8-0.40.00.9
Extinction: sum of active levers before priming1.01.03.1-1.20.30.7-0.0-0.50.30.8-1.50.51.8-1.8-0.61.60.3
Active lever presses in extinction session 60.30.30.8-0.90.80.8-0.7-0.70.20.5-0.20.5-0.30.30.2-0.60.6
Delta distance traveled before/after self-admin1.81.93.0-0.5-1.3-1.61.21.5-1.5-1.71.5-1.6-1.71.70.9-0.5-1.4
Delta ambulatory time before/after self-admin2.32.54.3-0.3-1.4-1.91.61.8-1.5-2.11.7-1.9-2.02.00.7-0.4-1.5
Time in closed arm before self-admin0.60.74.02.00.6-0.60.40.70.9-0.80.3-0.6-0.80.8-1.00.30.0
Time in closed arm after self-admin0.20.20.6-0.1-0.4-0.70.40.7-0.2-0.50.5-0.4-0.70.7-0.0-0.4-0.0
Time in open arm before self-admin0.70.71.9-1.10.01.3-1.0-1.4-0.31.2-0.41.10.5-0.50.7-0.60.4
Time in open arm after self-admin0.40.40.9-0.60.60.9-0.7-0.90.10.8-0.40.80.6-0.60.2-0.30.6
Sum of active levers in priming session hrs 5-60.80.83.80.1-0.1-0.1-0.20.00.60.5-1.30.11.3-1.3-1.22.00.2
Time to tail flick, vehicle, before self-admin0.30.31.00.30.3-0.5-0.10.2-0.3-0.30.5-0.7-0.90.90.5-1.00.2
Time to tail flick, vehicle, after self-admin1.71.83.5-1.30.61.3-1.5-1.50.41.8-1.91.41.7-1.7-0.10.91.0
Time to tail flick, test, before self-admin0.40.40.80.20.80.4-0.7-0.60.50.8-0.90.60.7-0.7-0.40.70.1
Time to tail flick, test, after self-admin0.70.82.80.0-0.3-1.40.91.7-0.4-1.20.1-1.4-0.40.4-0.50.8-0.2
Delta time to tail flick, vehicle, before/after SA1.21.23.0-1.3-0.20.9-0.6-0.90.21.0-1.51.01.7-1.7-0.41.70.2
Delta time to tail flick, test, before/after SA1.41.23.3-0.2-1.3-1.51.41.8-1.2-1.30.8-1.6-0.80.80.6-0.2-0.7
Ambulatory time before self-admin0.10.11.01.0-0.0-0.00.3-0.20.30.0-0.1-0.10.2-0.2-0.10.3-0.3
Ambulatory time after self-admin2.02.24.41.1-1.1-2.01.61.7-0.8-2.11.4-2.0-1.61.60.20.1-1.4
Total heroin consumption0.20.20.8-0.60.5-0.90.40.80.2-0.5-0.0-0.6-0.10.1-0.40.20.1
Area under the delay curve0.30.41.4-0.9-0.40.00.90.1-0.80.20.30.1-0.30.31.2-0.7-0.6
Delay disc. indifference point, 0s delay0.40.41.6-0.80.7-0.30.40.2-0.0-0.50.6-0.3-0.90.90.1-1.20.9
Delay disc. indifference point, 16s delay0.40.42.00.4-1.4-0.10.80.2-0.80.00.2-0.20.2-0.21.00.2-1.3
Delay disc. indifference point, 2s delay0.91.07.9-2.80.80.6-0.0-0.5-0.50.40.30.5-0.50.50.9-1.50.7
Delay disc. indifference point, 24s delay0.50.51.80.3-1.3-0.30.80.3-1.00.20.1-0.00.4-0.41.20.2-1.3
Delay disc. indifference point, 4s delay0.30.41.4-0.71.00.50.0-0.50.40.50.10.6-0.40.40.1-1.20.7
Delay disc. indifference point, 8s delay0.50.51.5-1.0-0.8-0.31.10.3-1.10.00.3-0.1-0.10.11.2-0.2-1.0
Delay discount exponential model param0.20.20.90.90.2-0.2-0.60.10.6-0.5-0.1-0.40.0-0.0-1.00.50.4
Delay discount hyperbolic model param0.30.31.31.1-0.1-0.5-0.40.40.4-0.70.1-0.6-0.00.0-0.80.60.0
Fecal boli incidents, locomotor time 10.70.82.2-0.7-1.4-0.01.40.1-1.50.10.10.00.3-0.31.40.2-1.4
Change in fecal boli incidents, locomotor task2.01.93.3-0.4-0.7-1.51.01.5-1.2-1.31.6-1.5-1.81.81.3-1.4-1.4
Time >=10cm from walls, locomotor time 13.33.36.10.2-2.0-1.91.81.8-2.4-1.91.9-1.9-1.41.42.1-0.9-2.5
Bouts of movement, locomotor time 10.30.32.2-1.5-0.20.3-0.1-0.4-0.8-0.30.30.10.0-0.00.7-0.4-0.3
Total resting periods, locomotor time 10.60.62.1-1.5-0.4-0.10.40.1-1.2-0.70.9-0.3-0.70.71.2-1.0-0.6
Rest time, locomotor task time 10.91.04.9-2.2-0.0-0.00.3-0.1-0.9-0.71.0-0.2-1.11.11.0-1.60.1
Distance moved, locomotor task time 10.40.52.11.5-0.2-0.1-0.20.20.50.6-0.90.20.8-0.8-0.51.2-0.3
Vertical activity count, locomotor time 11.11.23.81.50.00.3-0.5-0.21.10.7-1.30.51.5-1.5-1.51.90.2
Time >=10cm from walls, locomotor time 20.30.30.7-0.3-0.6-0.70.70.7-0.7-0.80.5-0.8-0.30.30.4-0.4-0.2
Bouts of movement, locomotor time 20.60.72.1-0.2-0.10.3-0.7-0.30.7-0.1-0.80.21.3-1.3-1.41.40.7
Total resting periods, locomotor time 20.60.61.7-0.30.30.5-1.0-0.50.80.0-0.70.41.1-1.1-1.31.00.9
Rest time, locomotor task time 20.91.14.3-2.10.80.1-0.4-0.1-0.6-0.41.1-0.1-1.21.21.0-2.00.3
Distance moved, locomotor task time 20.30.31.00.9-0.4-0.10.30.10.20.4-0.70.10.7-0.7-0.41.0-0.2
Vertical activity count, locomotor time 20.30.41.61.2-0.6-0.10.20.10.20.2-0.5-0.00.8-0.8-0.41.1-0.3
Weight adjusted by age0.30.41.40.10.70.0-0.4-0.2-0.30.30.50.0-0.90.91.1-1.2-0.4
Seeking ratio, delayed vs. immediate footshock1.92.23.10.3-1.4-1.51.71.6-1.6-1.41.6-1.4-1.71.71.4-0.8-1.8
Locomotion in novel chamber1.62.04.3-0.7-1.7-1.91.71.7-1.4-2.11.0-2.0-1.01.00.30.6-1.4
Locomotion in novel chamber post-restriction0.20.20.7-0.3-0.6-0.70.50.5-0.6-0.80.3-0.70.0-0.00.20.1-0.3
Progressive ratio0.30.41.6-1.30.10.8-0.1-0.6-0.10.70.10.8-0.00.00.8-0.80.2
Food seeking constrained by brief footshock0.10.20.7-0.8-0.1-0.20.70.4-0.5-0.40.2-0.3-0.10.10.2-0.2-0.4
Seeking ratio, punishment vs. effort0.20.20.70.80.1-0.40.00.40.1-0.4-0.3-0.50.3-0.3-0.80.9-0.1
Run reversals in cocaine runway, females0.50.52.60.2-0.20.40.0-0.20.40.3-0.90.41.0-1.0-1.01.6-0.0
Run reversals in cocaine runway, males0.20.10.5-0.10.1-0.7-0.00.7-0.0-0.5-0.0-0.6-0.10.1-0.50.5-0.2
Latency to leave start box in cocaine runway0.20.20.50.7-0.6-0.4-0.00.3-0.4-0.10.4-0.3-0.70.70.5-0.3-0.5
Latency to leave start box in cocaine runway, F1.21.34.1-0.1-1.2-0.70.60.6-1.7-0.51.2-0.6-1.41.42.0-1.2-1.3
Latency to leave start box in cocaine runway, M0.50.52.10.80.20.2-0.6-0.21.10.2-0.70.20.5-0.5-1.41.10.7
Cd content in liver0.50.51.4-0.1-1.2-0.71.10.7-0.9-0.80.4-0.70.1-0.10.30.5-1.1
Co content in liver0.80.91.8-0.30.40.7-0.9-0.71.00.8-1.20.71.3-1.3-1.31.30.8
Cu content in liver0.70.93.1-1.80.21.1-0.8-1.1-0.11.3-0.81.10.9-0.90.5-0.10.6
Fe content in liver1.51.83.9-0.1-1.1-1.11.21.1-1.5-0.71.5-1.1-1.71.72.0-1.7-1.0
K content in liver1.31.32.8-1.71.01.3-1.3-1.30.71.0-1.01.31.3-1.3-0.60.21.5
Mg content in liver2.02.03.0-1.30.91.6-1.6-1.60.91.6-1.61.61.7-1.7-0.90.71.6
Mn content in liver0.20.21.0-1.00.30.5-0.4-0.5-0.00.7-0.20.5-0.10.10.2-0.60.3
Na content in liver0.60.62.9-1.70.81.0-0.6-1.00.10.8-0.21.00.3-0.30.3-0.70.8
Rb content in liver0.10.20.70.4-0.60.20.0-0.2-0.60.5-0.30.20.3-0.30.80.0-0.2
Se content in liver1.01.22.00.3-1.3-1.21.41.2-1.1-0.91.0-1.2-1.11.11.0-0.4-1.3
Sr content in liver1.21.12.01.4-0.6-1.31.31.3-0.2-1.41.0-1.3-0.80.8-0.20.2-1.3
Zn content in liver0.30.31.11.0-0.7-0.60.50.60.0-0.4-0.0-0.60.1-0.1-0.41.0-0.8