Rab6b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009198 0.08 0.05 1.3e-12 0.1 0.09 0.08 0.09 3.7e-11 2.3e-10 1.6e-09 4.7e-10
2 Adipose mRNA stability ENSRNOG00000009198 0.08 0.05 2.6e-12 0.1 0.09 0.08 0.08 8.6e-11 5.1e-10 1.5e-09 2.0e-09
3 BLA gene expression ENSRNOG00000009198 0.13 0.06 7.7e-09 0.14 0.09 0.14 0.13 1.0e-07 1.1e-05 6.8e-08 1.4e-07
4 BLA mRNA stability ENSRNOG00000009198 0.07 0.05 9.8e-04 0.04 0.02 0.04 0 3.6e-03 4.7e-02 3.8e-03 2.1e-01
5 Brain gene expression ENSRNOG00000009198 0.09 0.04 5.0e-13 0.14 0.14 0.13 0.14 9.9e-13 7.6e-13 5.0e-12 1.2e-12
6 Brain mRNA stability ENSRNOG00000009198 0.1 0.05 0.0e+00 0.19 0.2 0.2 0.2 1.9e-17 1.6e-18 4.5e-18 3.7e-18
7 LHb gene expression ENSRNOG00000009198 0.11 0.08 9.9e-03 0.04 0.01 0.04 0.02 4.5e-02 1.4e-01 4.1e-02 1.1e-01
8 Liver gene expression ENSRNOG00000009198 0.07 0.04 4.0e-13 0.12 0.11 0.12 0.12 4.7e-13 1.4e-12 7.8e-13 5.1e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.41.43.6-0.8-0.8-0.4-1.9-1.2-1.3-1.6-0.8
BMI without tail2.04.29.2-1.6-1.5-1.4-3.0-2.2-2.1-2.5-1.6
Body weight1.97.817.0-2.5-2.4-1.2-4.1-2.7-2.9-3.1-2.5
Epididymis fat weight0.20.41.5-0.2-0.5-0.1-0.7-0.5-0.7-1.2-0.2
Glucose1.62.57.9-1.3-1.2-0.6-2.8-1.6-1.6-1.2-1.3
Heart weight0.40.61.3-0.4-0.4-0.3-1.1-0.7-0.9-1.1-0.4
Left kidney weight1.44.05.4-2.3-1.9-2.3-1.1-2.1-1.9-1.6-2.3
Right kidney weight0.41.21.9-1.4-0.6-1.1-1.1-1.2-1.1-0.9-1.4
Tail length1.85.412.0-2.0-1.9-1.4-3.5-2.4-2.3-2.5-2.0
Length with tail1.76.311.5-2.5-2.4-1.3-3.4-2.5-2.5-2.4-2.5
Length without tail0.40.91.4-1.1-1.2-0.2-1.1-0.8-1.0-0.7-1.1
Liver weight, left0.00.00.10.20.2-0.00.30.10.10.00.2
Liver weight, right0.20.30.8-0.4-0.3-0.5-0.9-0.6-0.4-0.5-0.4
Parametrial fat weight0.81.64.1-0.8-1.0-0.5-2.0-1.2-1.4-1.6-0.8
Retroperitoneal fat weight0.31.13.40.90.81.4-1.80.50.4-0.50.9
Intraocular pressure0.71.12.0-0.9-0.9-1.20.1-1.1-1.2-1.4-0.9
Extensor digitorum longus weight0.20.71.50.90.71.0-1.20.50.80.50.9
Soleus weight4.011.826.2-3.1-3.1-2.2-5.1-3.6-3.2-3.3-3.1
Tibialis anterior weight0.00.10.20.40.30.3-0.00.40.50.40.4
Tibia length1.23.54.5-2.1-2.0-2.1-0.3-1.9-2.0-1.6-2.1
Number of licking bursts0.20.20.4-0.4-0.7-0.2-0.4-0.4-0.6-0.6-0.4
Food consumed during 24 hour testing period1.11.31.8-1.3-1.1-0.8-0.9-1.2-1.4-0.9-1.3
Times rat made contact with spout0.10.20.5-0.7-0.4-0.1-0.1-0.2-0.30.2-0.7
Mean time between licks in bursts0.81.22.21.10.81.50.81.31.01.01.1
Mean num. licks in bursts0.10.10.2-0.40.0-0.30.2-0.10.10.4-0.4
Std. dev. time between licks in bursts5.36.37.52.62.32.71.92.72.62.62.6
Water consumed over 24 hours0.30.40.6-0.8-0.7-0.70.4-0.4-0.5-0.2-0.8
Indifference point 0 sec0.40.71.3-1.0-0.8-1.1-0.4-0.9-0.7-0.5-1.0
Indifference point AUC1.01.22.10.91.41.00.21.11.41.30.9
Indifference point function ln k0.40.61.1-0.6-1.1-1.00.4-0.7-0.8-0.9-0.6
Indifference point function log k0.40.61.1-0.6-1.1-1.00.4-0.7-0.8-0.9-0.6
Delay discounting total patch changes 0 sec0.10.20.4-0.6-0.4-0.6-0.0-0.4-0.3-0.0-0.6
Delay discounting total patch changes 12 sec0.30.41.00.30.70.30.40.61.01.00.3
Delay discounting total patch changes 18 sec0.40.60.9-0.9-0.6-0.6-0.8-0.8-0.6-0.6-0.9
Delay discounting total patch changes 24 sec0.00.00.1-0.20.20.1-0.20.10.20.3-0.2
Delay discounting total patch changes 6 sec0.10.20.8-0.4-0.2-0.90.5-0.3-0.00.1-0.4
Delay discounting time to switch 0 sec0.50.71.1-0.8-1.0-0.8-0.2-0.8-1.0-1.1-0.8
Delay discounting water rate 0 sec0.50.71.30.80.91.1-0.80.60.81.00.8
Delay discounting water rate 12 sec0.60.93.7-0.8-0.70.0-1.9-0.8-0.9-0.7-0.8
Delay discounting water rate 18 sec0.71.02.1-0.9-1.2-0.5-1.4-1.0-1.0-0.7-0.9
Delay discounting water rate 24 sec0.30.41.2-0.1-0.6-0.4-1.1-0.8-0.6-0.8-0.1
Delay discounting water rate 6 sec0.30.52.7-0.4-0.20.5-1.6-0.4-0.4-0.5-0.4
Locomotor activity1.01.52.6-1.4-1.3-0.4-1.6-1.0-1.2-1.0-1.4
Locomotor testing distance1.93.13.9-2.0-1.9-1.2-1.8-1.7-1.9-1.7-2.0
Locomotor testing rearing0.30.40.70.70.60.70.20.80.90.70.7
Light reinforcement 10.20.42.60.40.30.5-1.6-0.10.0-0.50.4
Light reinforcement 21.52.04.1-1.2-1.1-0.9-1.8-1.4-1.3-2.0-1.2
Reaction time number correct0.20.20.5-0.3-0.3-0.6-0.7-0.5-0.2-0.6-0.3
Reaction time mean minus median0.40.51.40.50.51.2-0.00.80.71.00.5
Reaction time mean minus median AUC0.50.72.30.40.51.5-0.60.80.71.00.4
Reaction time num false alarms0.70.91.31.11.00.60.90.91.10.91.1
Reaction time num false alarms AUC0.30.40.60.70.70.20.60.50.70.60.7
Reaction time trials correct on left0.20.20.5-0.3-0.3-0.6-0.7-0.5-0.2-0.6-0.3
Reaction time trials on left0.10.20.5-0.3-0.3-0.5-0.7-0.5-0.2-0.6-0.3
Reaction time mean0.60.81.40.80.61.20.81.10.81.00.8
Reaction time mean AUC0.50.71.20.80.51.10.91.00.60.90.8
Median of all reaction times0.40.51.00.70.60.81.00.80.50.70.7
Reaction time omissions1.41.93.61.71.21.90.31.51.30.71.7
Reaction time false alarm rate0.30.40.60.60.70.40.60.70.70.80.6
Reaction time premature initiation rate0.60.85.5-0.20.10.5-2.4-0.3-0.0-0.1-0.2
Reaction time premature initiations0.50.75.5-0.20.20.3-2.3-0.40.1-0.2-0.2
Std. dev. reaction times0.81.11.81.00.71.40.51.21.01.31.0
Reaction time trials completed0.10.20.5-0.3-0.3-0.5-0.7-0.5-0.2-0.6-0.3
Reaction time trials AUC0.20.30.6-0.3-0.3-0.6-0.8-0.6-0.2-0.7-0.3
Social response proportion0.20.20.40.40.40.70.30.60.60.40.4
Social responses1.01.31.81.41.31.3-0.51.01.21.01.4
Social time3.24.15.02.01.92.02.02.22.11.92.0
Conditioned locomotion0.10.10.4-0.4-0.5-0.60.4-0.2-0.2-0.1-0.4
Cocaine response after cond. corrected0.60.61.20.80.81.1-0.70.70.70.70.8
Cocaine response after cond. not corrected0.30.30.80.50.60.8-0.90.30.40.40.5
Cocaine response before conditioning0.50.60.8-0.7-0.7-0.9-0.4-0.9-0.9-0.9-0.7
Saline control response1.82.43.2-1.7-1.6-1.1-1.3-1.6-1.8-1.5-1.7
Condit. Reinf. active minus inactive responses3.84.76.92.22.22.61.12.42.22.02.2
Condit. Reinf. active-inactive response ratio1.91.95.01.41.42.2-0.51.41.11.01.4
Condit. Reinf. active responses4.96.88.52.72.62.91.62.92.72.52.7
Condit. Reinf. inactive responses3.03.76.71.91.71.12.62.02.12.01.9
Condit. Reinf. lever presses2.94.05.02.01.92.21.22.22.22.22.0
Condit. Reinf. lever reinforcers received5.47.69.52.92.83.11.73.02.82.62.9
Pavlov. Cond. lever latency4.56.17.1-2.5-2.5-2.7-1.4-2.6-2.6-2.6-2.5
Pavlov. Cond. magazine entry latency2.73.24.61.71.81.51.71.91.92.11.7
Pavlov. Cond. change in total contacts4.56.28.62.62.52.91.22.72.52.52.6
Pavlov. Cond. index score4.15.46.22.42.42.31.72.42.42.52.4
Pavlov. Cond. latency score3.84.85.72.32.22.01.82.32.32.42.3
Pavlov. Cond. lever contacts3.54.85.82.22.22.41.42.42.32.42.2
Pavlov. Cond. magazine entry number5.77.08.4-2.7-2.7-2.3-2.4-2.7-2.7-2.9-2.7
Pavlov. Cond. intertrial magazine entries1.01.31.71.11.01.31.01.31.11.11.1
Pavlov. Cond. lever-magazine prob. diff.4.86.37.02.62.52.51.82.72.62.62.6
Pavlov. Cond. response bias6.28.69.83.03.03.11.83.13.13.13.0
Conditioned reinforcement - actives1.71.62.8-1.4-1.1-0.2-1.7-1.1-1.6-1.1-1.4
Conditioned reinforcement - inactives1.21.42.0-1.4-0.9-0.3-1.4-1.0-1.4-1.2-1.4
Conditioned locomotion0.40.51.0-0.7-0.6-0.7-0.3-0.8-1.0-0.7-0.7
Intermittent access intake day 1-15 change0.40.42.4-0.40.30.8-1.6-0.10.00.1-0.4
Intermittent access intake escalation0.60.63.2-0.7-0.10.3-1.8-0.5-0.4-0.4-0.7
Intermittent access intake escalation 20.20.20.7-0.40.20.3-0.8-0.1-0.00.2-0.4
Intermitt. access day 1 inactive lever presses0.60.71.41.20.80.70.80.70.50.01.2
Intermitt. access day 15 inactive lever presses0.40.52.10.70.6-0.11.50.40.3-0.20.7
Intermitt. access escalation Index0.10.10.1-0.3-0.1-0.2-0.3-0.2-0.1-0.3-0.3
Intermittent access day 1 total infusions0.60.71.7-0.5-0.8-0.5-0.8-0.9-1.2-1.3-0.5
Intermittent access day 15 total infusions0.80.93.8-0.8-0.40.2-2.0-0.8-0.9-0.8-0.8
Intermittent access terminal intake (last 3 days)1.82.05.9-1.3-0.9-0.2-2.4-1.3-1.5-1.3-1.3
Intermittent access total infusions1.61.83.8-1.1-1.0-0.3-1.9-1.3-1.6-1.6-1.1
Intermittent access day 1 locomotion0.00.00.20.20.3-0.1-0.4-0.1-0.10.00.2
Intermittent access day 15 total locomotion2.32.43.7-1.4-1.4-1.2-1.9-1.7-1.7-1.6-1.4
Intermittent access total locomotion0.80.92.0-0.4-0.7-0.9-1.4-1.1-1.0-1.3-0.4
Intermittent access standard deviation1.01.01.71.01.21.30.41.10.91.11.0
Cocaine induced anxiety0.40.40.8-0.7-0.7-0.9-0.2-0.6-0.4-0.8-0.7
Post-drug Anxiety0.10.20.4-0.3-0.4-0.6-0.2-0.4-0.2-0.6-0.3
Baseline Anxiety0.10.10.30.30.10.5-0.20.1-0.00.10.3
Lifetime Intake1.21.43.2-0.9-0.90.0-1.8-1.0-1.5-1.4-0.9
Incentive Sensitization - Responses1.51.51.9-1.4-0.9-1.1-1.3-1.3-1.3-0.8-1.4
Incentive Sensitization - Breakpoint1.31.31.8-1.3-0.9-1.0-1.2-1.2-1.3-0.7-1.3
Progressive ratio test 1 active lever presses1.01.01.7-1.1-1.0-0.5-1.1-1.0-1.3-0.9-1.1
Progressive ratio test 1 breakpoint0.90.91.5-0.9-1.0-0.4-1.2-0.9-1.2-0.9-0.9
Progressive ratio test 1 inactive lever presses0.10.20.60.2-0.30.2-0.2-0.2-0.6-0.80.2
Progressive ratio test 2 active lever presses2.32.43.9-1.6-1.3-0.9-2.0-1.6-1.8-1.4-1.6
Progressive ratio test 2 breakpoint1.51.63.3-1.4-0.9-0.6-1.8-1.3-1.4-1.0-1.4
Progressive ratio test 2 inactive lever presses0.10.10.4-0.1-0.00.2-0.7-0.3-0.5-0.3-0.1
Total sessions with >9 infusions0.20.21.30.2-0.21.1-0.30.3-0.30.10.2
Short access day 1 total inactive lever presses0.20.20.5-0.3-0.3-0.40.2-0.4-0.6-0.7-0.3
Short access day 10 total inactive lever presses1.41.52.31.51.50.71.31.11.10.81.5
Short access day 1 total infusions0.30.30.7-0.6-0.50.1-0.4-0.4-0.8-0.3-0.6
Short access day 10 total infusions1.01.12.5-0.7-0.70.0-1.6-0.9-1.3-1.4-0.7
Short access total infusions0.50.61.6-0.6-0.60.6-1.3-0.5-1.1-0.6-0.6
Short access day 1 locomotion1.11.22.2-1.0-1.3-0.5-1.5-1.0-1.2-0.9-1.0
Short access day 10 total locomotion1.01.12.31.51.20.50.50.81.00.71.5
Short access total locomotion0.30.31.1-0.2-0.4-0.1-1.1-0.5-0.6-0.5-0.2
Compulsive drug intake2.12.13.51.41.40.51.91.41.71.41.4
One hour access (0.3 mA shock)0.60.73.3-0.8-0.30.1-1.8-0.7-0.7-0.6-0.8
One hour access (shock baseline)3.03.48.4-1.7-1.5-0.5-2.9-1.8-2.0-1.9-1.7
Number of responses in last shaping day0.10.10.10.10.30.40.30.30.10.20.1
Context. condit. distance diff. score3.84.65.7-2.2-2.2-1.6-2.1-2.2-2.4-2.3-2.2
Locomotion velocity, session 10.60.61.9-0.9-0.7-1.4-0.2-0.9-0.6-0.4-0.9
Locomotion distance, session 11.11.52.3-1.2-1.1-1.5-0.1-1.3-1.3-1.4-1.2
Locomotion velocity, session 20.10.20.40.10.4-0.3-0.30.10.70.60.1
Locomotion distance, session 20.00.00.10.10.3-0.4-0.2-0.20.1-0.10.1
Locomotion velocity, session 30.40.51.1-0.4-0.8-1.10.0-0.8-0.8-0.8-0.4
Locomotion distance, session 30.20.20.6-0.1-0.3-0.80.7-0.3-0.4-0.3-0.1
Stereotopy head waving bouts, day 30.40.50.80.90.60.70.30.80.80.50.9
Stereotopy head waving duration, day 30.20.20.40.60.20.40.00.40.50.20.6
Locomotion velocity, session 70.90.91.4-1.0-1.1-1.2-0.3-1.0-0.9-1.0-1.0
Locomotion distance, session 70.00.10.10.30.2-0.20.10.10.40.10.3
Stereotopy head waving bouts, day 70.60.61.0-0.8-1.0-0.70.4-0.6-0.9-0.8-0.8
Stereotopy head waving duration, day 70.60.71.1-0.9-1.0-0.70.1-0.8-1.0-0.9-0.9
Locomotion velocity, session 83.23.95.8-1.7-2.1-1.9-1.3-2.1-2.2-2.4-1.7
Locomotion distance, session 83.75.66.9-2.2-2.2-2.4-2.0-2.6-2.6-2.6-2.2
Degree of sensitization distance0.20.20.40.30.40.6-0.60.30.4-0.00.3
Degree of sensitization stereotypy1.82.02.8-1.7-1.6-1.2-0.2-1.3-1.7-1.3-1.7
Condit. Reinf. active minus inactive responses0.00.10.40.00.00.1-0.6-0.00.10.20.0
Condit. Reinf. active-inactive response ratio2.22.32.8-1.7-1.5-1.5-1.3-1.6-1.6-1.3-1.7
Condit. Reinf. active responses0.81.01.31.11.01.2-0.20.91.01.01.1
Condit. Reinf. inactive responses2.02.43.21.71.61.80.51.61.61.41.7
Incentive salience index mean0.40.50.91.00.60.60.10.60.80.71.0
Condit. Reinf. lever presses1.21.72.81.71.20.90.61.21.51.31.7
Time in familiar zone, hab. session 10.70.64.00.10.2-0.32.00.50.30.70.1
Time in novel zone, hab. session 12.32.27.8-1.1-1.2-0.4-2.8-1.3-1.2-1.7-1.1
Total zone transitions, hab. session 10.20.30.90.60.40.6-0.90.10.1-0.20.6
Total locomotion distance, hab. session 10.50.70.91.00.90.70.70.80.80.81.0
Locomotion velocity, hab. session 10.50.81.11.01.00.70.70.80.80.91.0
Time in familiar zone, hab. session 21.01.02.20.71.20.81.11.01.01.50.7
Time in novel zone, hab. session 23.53.55.4-1.6-2.1-1.8-1.4-2.0-2.0-2.3-1.6
Total zone transitions, hab. session 20.40.51.30.91.10.40.20.50.60.50.9
Total locomotion distance, hab. session 21.62.13.91.42.00.71.51.31.51.51.4
Locomotion velocity, hab. session 21.92.64.21.62.00.71.91.51.61.61.6
Novel to familiar place preference ratio1.51.63.2-1.3-1.8-1.1-0.3-1.2-1.4-1.2-1.3
Novelty place preference2.32.44.4-1.6-2.1-1.4-0.5-1.5-1.7-1.5-1.6
Time in novel zone, NPP test1.92.03.7-1.5-1.9-1.1-0.6-1.3-1.6-1.4-1.5
Total zone transitions, NPP test0.30.41.10.81.00.5-0.20.40.50.20.8
Total locomotion distance, NPP test1.52.13.41.81.91.30.61.41.51.01.8
Locomotion velocity, NPP test1.42.03.11.71.81.10.81.31.40.91.7
Pavlov. Cond. lever latency1.21.53.2-1.2-1.2-0.1-1.8-1.0-1.3-1.4-1.2
Pavlov. Cond. magazine entry latency0.50.62.80.40.7-0.61.70.40.50.70.4
Pavlov. Cond. change in total contacts1.71.83.11.11.50.71.61.21.31.81.1
Pavlov. Cond. index score1.01.34.00.91.1-0.32.00.81.01.20.9
Pavlov. Cond. latency score0.60.83.00.60.7-0.61.70.40.70.90.6
Pavlov. Cond. lever contacts0.40.51.80.50.5-0.41.40.40.60.80.5
Pavlov. Cond. magazine entry number1.21.54.7-1.0-1.20.1-2.2-1.0-1.1-1.3-1.0
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.1-0.2-0.30.2-0.2-0.1-0.2-0.1
Pavlov. Cond. lever-magazine prob. diff.1.51.94.71.21.40.12.21.21.41.61.2
Pavlov. Cond. response bias0.91.12.80.91.1-0.01.70.81.01.30.9
Bone: apparent density0.81.42.2-1.5-1.3-1.0-0.4-1.2-1.3-0.7-1.5
Bone surface0.30.61.2-0.8-0.7-1.01.1-0.5-0.7-0.1-0.8
Bone volume0.40.81.1-1.0-1.0-1.00.5-0.8-0.9-0.4-1.0
Bone: connectivity density0.20.30.5-0.6-0.7-0.2-0.3-0.5-0.7-0.3-0.6
Bone: cortical apparent density0.20.21.2-0.2-0.1-0.61.10.10.20.3-0.2
Bone: cortical area2.84.25.5-2.2-2.1-2.3-0.9-2.1-2.1-1.9-2.2
Bone: cortical porosity1.11.22.2-1.3-1.2-1.50.8-1.0-1.0-0.5-1.3
Bone: cortical porosity1.21.32.3-1.3-1.3-1.50.8-1.0-1.1-0.6-1.3
Bone: cortical thickness1.42.32.7-1.6-1.5-1.4-1.2-1.6-1.5-1.5-1.6
Bone: cortical thickness0.40.50.7-0.8-0.6-0.7-0.3-0.7-0.7-0.8-0.8
Bone: cortical tissue density0.20.21.3-0.1-0.1-0.51.10.20.30.3-0.1
Bone: elastic displacement1.51.62.5-1.4-1.0-0.8-1.6-1.3-1.3-1.2-1.4
Bone: elastic work5.16.77.7-2.8-2.5-2.4-2.0-2.7-2.7-2.7-2.8
Bone: endosteal estimation1.22.54.7-1.5-1.7-2.20.1-1.7-1.6-1.5-1.5
Bone: endosteal perimeter0.20.51.9-0.4-0.5-1.40.5-0.7-0.5-0.5-0.4
Bone: final force1.01.62.3-1.4-1.3-1.5-0.8-1.4-1.2-1.0-1.4
Bone: final moment1.52.43.1-1.7-1.6-1.8-0.9-1.7-1.5-1.3-1.7
Bone: marrow area1.22.64.9-1.6-1.7-2.20.0-1.8-1.7-1.6-1.6
Bone: maximum diameter1.22.13.2-1.6-1.5-1.8-0.3-1.5-1.5-1.3-1.6
Bone: maximum force2.95.07.5-2.5-2.3-2.7-0.8-2.4-2.3-2.0-2.5
Bone: maximum moment3.66.28.9-2.8-2.5-3.0-0.9-2.7-2.5-2.2-2.8
Bone: minimum diameter1.62.95.2-1.6-1.8-2.3-0.1-1.8-1.8-1.7-1.6
Bone: periosteal estimation3.26.610.2-2.6-2.7-3.2-0.7-2.7-2.6-2.4-2.6
Bone: periosteal perimeter0.91.43.0-1.1-1.3-1.70.1-1.3-1.2-1.1-1.1
Bone: post-yield work0.10.10.20.50.40.2-0.40.10.20.20.5
Bone: stiffness0.50.71.9-1.0-0.8-1.40.5-0.8-0.6-0.2-1.0
Bone: tissue strength2.92.87.8-1.5-1.3-1.0-2.8-1.7-1.5-1.5-1.5
Bone: trabecular number0.10.10.2-0.5-0.40.00.1-0.2-0.5-0.0-0.5
Bone: trabecular spacing1.62.03.11.81.51.70.11.41.50.91.8
Bone: trabecular thickness4.35.26.6-2.6-2.4-2.3-1.3-2.4-2.5-2.1-2.6
Bone: trabecular tissue density0.91.33.3-1.2-0.9-1.8-0.4-1.3-0.9-1.0-1.2
Breakpoint value in progressive ratio session1.11.31.71.20.81.20.81.21.11.31.2
Distance traveled before self-admin1.71.83.6-1.1-1.5-0.5-1.9-1.3-1.5-1.5-1.1
Distance traveled after self-admin0.30.40.6-0.8-0.6-0.0-0.6-0.5-0.7-0.2-0.8
Delta time in closed arm before/after self-admin1.61.63.7-0.8-1.0-1.9-0.4-1.6-1.3-1.4-0.8
Delta time in open arm before/after self-admin0.00.00.0-0.2-0.0-0.10.10.10.2-0.0-0.2
Diff in mean of infusions in LGA sessions0.10.20.80.30.00.90.00.50.20.10.3
Extinction: sum of active levers before priming0.10.10.5-0.2-0.7-0.4-0.1-0.3-0.3-0.2-0.2
Active lever presses in extinction session 60.20.20.90.1-0.30.5-1.0-0.1-0.3-0.50.1
Delta distance traveled before/after self-admin0.20.20.6-0.8-0.3-0.50.2-0.3-0.40.0-0.8
Delta ambulatory time before/after self-admin0.30.30.8-0.9-0.4-0.5-0.1-0.5-0.50.0-0.9
Time in closed arm before self-admin0.70.71.90.51.01.40.21.00.70.90.5
Time in closed arm after self-admin0.10.10.3-0.10.30.5-0.5-0.0-0.20.1-0.1
Time in open arm before self-admin0.50.51.0-0.8-1.0-0.7-0.2-0.7-0.7-0.3-0.8
Time in open arm after self-admin0.30.30.8-0.6-0.7-0.90.6-0.3-0.2-0.4-0.6
Sum of active levers in priming session hrs 5-60.00.00.10.0-0.30.1-0.3-0.1-0.10.30.0
Time to tail flick, vehicle, before self-admin0.40.41.30.30.51.2-0.50.60.40.60.3
Time to tail flick, vehicle, after self-admin0.50.50.70.60.70.80.70.80.70.70.6
Time to tail flick, test, before self-admin0.80.81.1-0.8-0.7-0.9-0.7-1.1-1.0-1.0-0.8
Time to tail flick, test, after self-admin1.81.93.4-0.9-1.2-1.8-0.7-1.7-1.5-1.8-0.9
Delta time to tail flick, vehicle, before/after SA0.30.31.70.40.1-0.61.30.00.1-0.20.4
Delta time to tail flick, test, before/after SA1.00.92.2-0.5-0.9-1.3-0.6-1.1-1.0-1.5-0.5
Ambulatory time before self-admin1.61.74.5-0.9-1.4-0.1-2.1-1.1-1.3-1.6-0.9
Ambulatory time after self-admin0.50.51.1-0.7-0.6-0.2-1.0-0.7-0.8-0.7-0.7
Total heroin consumption0.50.61.0-0.5-1.0-0.8-0.4-0.8-0.9-0.9-0.5
Area under the delay curve0.30.42.60.10.00.2-1.6-0.3-0.0-0.30.1
Delay disc. indifference point, 0s delay0.10.10.50.1-0.40.1-0.7-0.1-0.0-0.30.1
Delay disc. indifference point, 16s delay0.30.31.7-0.1-0.20.1-1.3-0.5-0.5-0.7-0.1
Delay disc. indifference point, 2s delay0.40.52.1-0.5-0.4-0.3-1.5-0.6-0.4-0.5-0.5
Delay disc. indifference point, 24s delay0.70.61.20.70.71.1-1.00.50.70.70.7
Delay disc. indifference point, 4s delay0.20.21.60.20.2-0.0-1.3-0.20.2-0.20.2
Delay disc. indifference point, 8s delay0.20.21.40.1-0.1-0.1-1.2-0.3-0.1-0.40.1
Delay discount exponential model param0.40.43.2-0.00.0-0.11.80.40.10.4-0.0
Delay discount hyperbolic model param0.40.43.00.00.0-0.11.70.30.00.30.0
Fecal boli incidents, locomotor time 10.91.01.51.21.11.2-0.50.90.90.51.2
Change in fecal boli incidents, locomotor task2.12.02.9-1.7-1.6-1.70.2-1.3-1.3-1.1-1.7
Time >=10cm from walls, locomotor time 10.50.50.70.40.70.60.80.80.70.80.4
Bouts of movement, locomotor time 10.10.10.30.40.5-0.10.50.20.40.20.4
Total resting periods, locomotor time 10.30.30.50.70.7-0.10.60.30.50.30.7
Rest time, locomotor task time 10.40.50.80.90.60.70.50.70.60.60.9
Distance moved, locomotor task time 11.21.31.6-1.3-1.1-1.1-0.9-1.2-1.1-1.0-1.3
Vertical activity count, locomotor time 10.00.00.10.10.2-0.20.20.00.2-0.10.1
Time >=10cm from walls, locomotor time 21.01.11.91.11.01.40.21.11.00.91.1
Bouts of movement, locomotor time 21.41.51.81.31.31.30.51.21.31.11.3
Total resting periods, locomotor time 21.31.41.81.31.31.20.61.21.31.11.3
Rest time, locomotor task time 20.20.20.30.40.60.30.40.60.60.50.4
Distance moved, locomotor task time 21.41.62.0-1.4-1.4-1.4-0.4-1.4-1.3-1.2-1.4
Vertical activity count, locomotor time 20.50.62.90.60.5-0.11.70.50.50.30.6
Weight adjusted by age0.10.20.4-0.2-0.3-0.5-0.3-0.4-0.4-0.6-0.2
Seeking ratio, delayed vs. immediate footshock0.40.51.5-0.3-0.5-1.21.0-0.5-0.5-0.7-0.3
Locomotion in novel chamber2.93.56.91.51.91.71.52.02.02.61.5
Locomotion in novel chamber post-restriction0.20.20.90.20.11.0-0.60.40.20.60.2
Progressive ratio4.24.95.62.32.12.32.02.42.22.02.3
Food seeking constrained by brief footshock1.51.92.6-1.3-1.6-1.0-0.9-1.4-1.6-1.6-1.3
Seeking ratio, punishment vs. effort5.26.47.3-2.6-2.5-2.5-2.1-2.7-2.6-2.4-2.6
Run reversals in cocaine runway, females1.41.31.81.01.00.91.31.31.41.31.0
Run reversals in cocaine runway, males2.01.92.9-1.7-0.9-1.3-1.5-1.5-1.3-0.9-1.7
Latency to leave start box in cocaine runway3.23.511.01.81.41.03.31.81.51.31.8
Latency to leave start box in cocaine runway, F2.02.24.71.51.01.22.21.61.31.41.5
Latency to leave start box in cocaine runway, M1.31.34.41.11.30.42.11.00.80.41.1
Cd content in liver1.92.14.4-1.4-1.0-1.0-2.1-1.5-1.4-1.5-1.4
Co content in liver0.10.10.2-0.4-0.5-0.1-0.4-0.3-0.3-0.4-0.4
Cu content in liver2.42.94.6-1.6-2.1-1.5-0.2-1.6-2.0-2.1-1.6
Fe content in liver1.01.22.0-1.0-1.2-0.6-1.1-1.1-1.3-1.4-1.0
K content in liver2.42.43.81.61.51.9-0.31.61.81.41.6
Mg content in liver1.51.52.81.21.31.7-0.21.31.31.21.2
Mn content in liver0.10.10.40.20.20.60.20.50.30.30.2
Na content in liver0.10.20.8-0.3-0.9-0.3-0.2-0.2-0.0-0.3-0.3
Rb content in liver0.50.62.00.50.51.1-1.40.40.50.20.5
Se content in liver0.10.10.2-0.3-0.5-0.3-0.1-0.4-0.4-0.4-0.3
Sr content in liver0.10.10.10.30.30.2-0.30.20.30.00.3
Zn content in liver0.50.61.60.50.81.3-0.90.50.50.50.5