Rnaseh2b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009192 0.1 0.05 1.5e-09 0.07 0.07 0.07 0.07 3.5e-08 4.9e-08 6.8e-08 2.0e-08
2 Adipose intron excision ratio chr15:36576723:36591389 0.05 0.03 2.1e-04 0.03 0.03 0.03 0.03 1.9e-04 3.7e-04 5.0e-04 5.3e-04
3 Adipose mRNA stability ENSRNOG00000009192 0.02 0.01 4.7e-03 0.02 0.01 0.02 0.02 1.2e-03 8.2e-03 3.8e-03 4.3e-03
4 BLA intron excision ratio chr15:36576723:36583517 0.06 0.04 1.2e-03 0.05 0.06 0.01 0.04 1.7e-03 6.4e-04 5.9e-02 4.5e-03
5 BLA intron excision ratio chr15:36576723:36591389 0.07 0.05 2.6e-03 0.02 0.02 0.01 0.01 3.3e-02 2.9e-02 1.4e-01 7.8e-02
6 BLA mRNA stability ENSRNOG00000009192 0.46 0.12 0.0e+00 0.35 0.41 0.41 0.42 9.3e-20 1.5e-23 1.2e-23 3.8e-24
7 Brain gene expression ENSRNOG00000009192 0.11 0.05 2.3e-08 0.09 0.09 0.08 0.09 2.3e-08 9.1e-09 1.6e-07 1.8e-08
8 Brain intron excision ratio chr15:36581962:36583517 0.03 0.02 3.0e-03 0.04 0.03 0.02 0.03 3.2e-04 1.7e-03 2.6e-03 4.9e-04
9 Brain mRNA stability ENSRNOG00000009192 0.49 0.11 0.0e+00 0.4 0.54 0.53 0.54 5.1e-39 6.5e-59 4.7e-58 1.5e-59
10 IL mRNA stability ENSRNOG00000009192 0.41 0.14 2.1e-05 0.12 0.12 0.19 0.2 1.0e-03 6.9e-04 2.1e-05 1.4e-05
11 LHb mRNA stability ENSRNOG00000009192 0.54 0.16 4.0e-06 0.09 0.17 0.15 0.13 3.2e-03 9.5e-05 1.7e-04 4.6e-04
12 Liver gene expression ENSRNOG00000009192 0.15 0.07 2.7e-12 0.05 0.1 0.1 0.1 2.5e-06 5.0e-11 3.6e-11 1.2e-10
13 Liver intron excision ratio chr15:36576723:36581882 0.06 0.03 2.3e-07 0.05 0.06 0.04 0.05 1.1e-06 6.7e-07 2.4e-05 5.2e-06
14 Liver mRNA stability ENSRNOG00000009192 0.08 0.05 1.4e-06 0.05 0.05 0.04 0.04 1.9e-06 3.7e-06 1.1e-05 9.0e-06
15 NAcc intron excision ratio chr15:36576723:36583517 0.29 0.13 1.2e-11 0.15 0.16 0.16 0.15 3.4e-11 4.2e-12 6.2e-12 2.4e-11
16 NAcc mRNA stability ENSRNOG00000009192 0.41 0.1 0.0e+00 0.31 0.44 0.44 0.45 3.2e-23 3.3e-36 3.7e-36 4.1e-37
17 OFC mRNA stability ENSRNOG00000009192 0.54 0.17 1.1e-05 0.07 0.19 0.06 0.1 8.8e-03 3.5e-05 2.0e-02 2.6e-03
18 PL intron excision ratio chr15:36576723:36583517 0.11 0.07 2.2e-06 0.08 0.08 0.08 0.08 6.0e-07 1.9e-06 2.1e-06 1.1e-06
19 PL mRNA stability ENSRNOG00000009192 0.49 0.11 0.0e+00 0.45 0.5 0.51 0.51 2.0e-37 1.1e-43 4.2e-44 9.9e-45

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
BMI with tail0.31.01.90.4-0.3-1.01.10.0-0.6-1.3-0.5-1.2-1.2-1.0-1.4-0.8-1.41.0-1.1-0.91.2-1.1
BMI without tail0.20.40.80.9-0.90.0-0.1-0.7-0.9-0.60.0-0.9-0.6-0.8-0.50.3-0.7-0.2-0.8-0.5-0.0-0.8
Body weight0.31.23.4-1.21.2-1.81.71.40.7-0.3-1.30.0-0.10.5-1.0-1.9-0.61.50.20.11.80.2
Epididymis fat weight1.02.46.6-1.21.10.7-0.91.01.71.81.21.92.11.91.40.31.9-1.31.92.6-0.81.8
Glucose0.91.43.10.9-0.9-1.00.9-0.3-1.3-1.8-0.6-1.5-1.5-1.5-1.7-0.5-1.50.6-1.5-0.80.7-1.5
Heart weight0.30.51.90.2-0.2-0.30.6-0.1-0.6-0.6-0.9-0.6-0.8-0.7-0.6-0.4-0.71.0-0.5-1.40.8-0.6
Left kidney weight1.44.09.8-0.90.8-2.63.12.10.0-2.0-2.7-0.6-1.0-0.6-3.1-2.8-2.12.8-0.60.33.0-0.6
Right kidney weight1.85.313.6-1.71.5-3.03.52.80.5-1.4-3.4-0.1-0.6-0.0-3.0-3.4-2.03.6-0.0-0.03.70.0
Tail length0.41.22.3-1.31.40.0-0.01.11.41.3-0.31.41.51.50.7-0.41.2-0.11.51.30.11.5
Length with tail0.51.93.8-1.81.8-0.50.31.51.81.5-0.31.71.61.90.8-0.91.3-0.01.71.70.31.7
Length without tail0.41.02.1-1.41.4-1.01.01.41.20.5-0.40.80.71.1-0.1-1.30.40.70.90.91.01.0
Liver weight, left2.03.28.8-0.80.8-2.92.71.8-0.1-1.0-3.0-0.3-0.6-0.2-2.2-2.7-1.72.8-0.2-1.02.6-0.2
Liver weight, right0.10.10.4-0.50.5-0.40.30.40.30.2-0.60.30.20.3-0.2-0.40.10.40.3-0.00.40.4
Parametrial fat weight2.24.49.60.1-0.32.3-2.9-1.10.82.33.01.51.81.53.02.32.5-3.11.41.7-3.01.4
Retroperitoneal fat weight0.62.03.6-1.10.91.1-1.30.41.61.61.51.61.81.41.60.81.8-1.31.61.9-1.01.5
Intraocular pressure0.71.03.8-0.10.12.0-1.5-0.80.41.10.80.60.60.31.71.41.2-0.80.6-0.5-1.10.6
Extensor digitorum longus weight2.911.634.3-3.13.1-5.95.14.51.6-0.9-4.50.80.11.4-3.6-5.5-1.64.60.90.74.90.9
Soleus weight0.30.92.5-0.40.4-1.51.30.5-0.1-0.5-1.1-0.4-0.6-0.4-1.0-1.1-1.11.6-0.4-1.51.5-0.4
Tibialis anterior weight3.010.433.5-1.91.8-5.85.13.60.4-1.8-4.1-0.4-1.00.3-4.0-5.2-2.74.6-0.3-0.34.9-0.4
Tibia length0.92.54.30.9-0.9-1.41.6-0.2-1.6-1.9-1.6-1.8-2.0-1.6-1.8-1.1-2.11.4-1.8-1.81.5-1.7
Number of licking bursts0.30.30.90.4-0.4-0.40.5-0.2-0.6-0.6-0.5-0.6-0.7-0.6-0.5-0.3-0.90.5-0.6-0.90.4-0.6
Food consumed during 24 hour testing period0.20.30.70.0-0.1-0.80.60.1-0.3-0.5-0.4-0.4-0.5-0.4-0.7-0.5-0.50.8-0.4-0.80.6-0.4
Times rat made contact with spout0.20.21.30.2-0.3-1.10.50.1-0.4-0.2-0.0-0.3-0.4-0.1-0.5-0.6-0.30.3-0.3-0.40.2-0.3
Mean time between licks in bursts1.21.63.51.9-1.70.9-1.0-1.9-1.6-0.90.7-1.4-1.2-1.60.01.4-0.6-0.8-1.5-1.4-0.9-1.4
Mean num. licks in bursts0.00.00.1-0.20.2-0.40.10.20.20.30.10.20.20.40.1-0.20.30.10.20.00.10.2
Std. dev. time between licks in bursts1.01.22.90.1-0.11.5-1.7-0.80.41.21.00.81.00.41.51.61.5-1.40.70.2-1.40.7
Water consumed over 24 hours0.20.30.8-0.60.3-0.90.70.50.10.2-0.70.20.10.3-0.3-0.8-0.20.90.2-0.60.70.2
Indifference point 0 sec0.20.31.5-0.20.30.2-0.5-0.50.20.90.40.20.30.61.20.20.6-0.50.3-0.7-0.60.4
Indifference point AUC1.31.62.71.4-1.6-0.90.2-1.0-1.6-1.60.7-1.6-1.4-1.6-1.40.2-1.5-0.0-1.6-0.9-0.1-1.7
Indifference point function ln k0.71.02.7-1.31.6-0.20.61.11.41.0-0.91.11.01.30.7-0.90.80.71.20.30.61.2
Indifference point function log k0.71.02.7-1.31.6-0.20.61.11.41.0-0.91.11.01.30.7-0.90.80.71.20.30.61.2
Delay discounting total patch changes 0 sec0.20.31.2-0.50.7-0.2-0.1-0.10.41.00.10.40.40.81.1-0.20.6-0.20.5-0.6-0.20.5
Delay discounting total patch changes 12 sec0.60.82.30.7-0.6-1.00.6-0.6-1.1-0.8-0.2-1.1-1.1-0.8-0.7-0.4-1.20.5-1.1-1.50.4-1.1
Delay discounting total patch changes 18 sec0.00.00.3-0.30.1-0.50.2-0.0-0.00.10.2-0.1-0.10.20.0-0.3-0.00.1-0.1-0.3-0.0-0.0
Delay discounting total patch changes 24 sec0.10.20.8-0.50.4-0.90.60.40.20.3-0.10.20.10.5-0.0-0.80.00.30.2-0.10.30.2
Delay discounting total patch changes 6 sec0.40.62.00.9-0.9-0.3-0.1-1.0-1.1-0.60.2-0.9-1.0-0.9-0.20.3-0.8-0.1-1.0-1.4-0.2-1.0
Delay discounting time to switch 0 sec0.40.52.0-0.40.10.8-0.70.30.40.8-0.40.90.90.80.60.41.1-0.80.71.4-0.70.8
Delay discounting water rate 0 sec0.40.71.9-0.81.0-1.21.30.80.4-0.1-0.60.0-0.20.3-0.4-1.4-0.51.40.2-0.71.30.2
Delay discounting water rate 12 sec2.23.37.1-2.52.6-1.92.32.51.90.7-1.81.30.81.5-0.4-2.7-0.02.51.40.02.41.4
Delay discounting water rate 18 sec2.83.710.6-1.51.8-2.83.22.30.7-0.8-2.4-0.0-0.50.4-1.7-3.3-1.53.10.2-0.73.10.1
Delay discounting water rate 24 sec1.11.53.9-1.82.0-0.71.11.71.60.9-0.91.20.81.40.4-1.50.31.31.20.31.21.3
Delay discounting water rate 6 sec1.72.45.3-2.22.2-1.61.92.11.50.8-1.61.10.81.5-0.3-2.30.12.01.30.01.91.3
Locomotor activity1.52.57.1-1.81.8-2.22.32.11.00.3-2.10.80.31.3-0.8-2.7-0.42.10.80.22.10.9
Locomotor testing distance0.40.61.5-1.11.1-0.60.60.80.71.0-0.70.80.61.20.6-1.00.40.40.70.10.60.9
Locomotor testing rearing0.20.42.80.3-0.2-0.10.3-0.5-0.6-0.1-0.7-0.5-0.6-0.30.3-0.3-0.70.6-0.6-1.70.4-0.5
Light reinforcement 10.20.30.7-0.70.5-0.80.60.80.40.2-0.50.50.30.6-0.3-0.90.00.40.50.60.40.4
Light reinforcement 21.01.32.2-0.40.21.1-1.3-0.20.81.31.31.11.41.01.51.01.4-1.41.11.3-1.31.0
Reaction time number correct0.20.31.20.6-0.80.1-0.2-0.8-0.8-0.3-0.0-0.6-0.6-0.60.00.4-0.40.0-0.6-1.1-0.3-0.6
Reaction time mean minus median0.40.51.0-0.90.6-0.20.31.00.90.5-0.10.90.90.70.1-0.40.30.70.90.70.60.8
Reaction time mean minus median AUC0.10.10.60.1-0.5-0.10.30.1-0.2-0.5-0.0-0.2-0.2-0.5-0.4-0.0-0.70.7-0.2-0.30.6-0.4
Reaction time num false alarms0.10.10.8-0.20.1-0.90.40.50.2-0.30.20.10.00.0-0.6-0.5-0.20.00.00.60.1-0.0
Reaction time num false alarms AUC0.20.31.5-0.10.0-1.20.70.60.0-0.6-0.0-0.1-0.3-0.1-1.0-0.7-0.40.2-0.20.60.3-0.3
Reaction time trials correct on left0.20.31.20.6-0.80.1-0.2-0.8-0.8-0.3-0.0-0.6-0.6-0.60.00.4-0.40.0-0.6-1.1-0.3-0.6
Reaction time trials on left0.30.41.50.8-1.00.2-0.3-0.9-0.9-0.40.1-0.7-0.7-0.80.00.5-0.5-0.0-0.7-1.2-0.3-0.7
Reaction time mean0.50.71.3-0.60.41.0-0.70.40.81.00.71.11.10.91.00.50.9-0.41.01.1-0.50.9
Reaction time mean AUC0.60.71.4-0.50.31.1-0.80.30.81.10.81.21.20.91.20.60.9-0.41.01.0-0.50.9
Median of all reaction times0.70.91.6-0.50.41.2-0.90.30.91.20.91.21.21.01.30.61.1-0.71.11.1-0.71.0
Reaction time omissions1.31.83.91.8-2.01.3-1.2-1.9-1.5-0.81.4-1.2-0.9-1.40.31.7-0.7-0.9-1.3-1.1-1.0-1.4
Reaction time false alarm rate0.20.31.4-0.20.2-1.20.80.70.1-0.6-0.0-0.1-0.2-0.0-1.0-0.8-0.40.2-0.20.80.4-0.2
Reaction time premature initiation rate0.81.13.0-1.51.4-0.60.51.51.40.6-0.41.21.11.1-0.3-0.80.90.21.31.70.31.2
Reaction time premature initiations0.30.41.1-1.00.8-0.30.20.90.90.4-0.20.80.70.6-0.2-0.40.60.00.91.10.00.8
Std. dev. reaction times0.10.20.5-0.2-0.10.7-0.50.10.40.40.60.60.60.30.40.50.4-0.20.50.7-0.20.4
Reaction time trials completed0.30.41.50.8-1.00.2-0.3-0.9-0.9-0.40.1-0.7-0.7-0.80.00.5-0.5-0.0-0.7-1.2-0.3-0.7
Reaction time trials AUC0.20.31.20.7-0.90.2-0.3-0.8-0.8-0.20.1-0.6-0.6-0.60.10.5-0.3-0.1-0.6-1.1-0.4-0.6
Social response proportion1.21.33.60.9-0.71.9-1.8-1.20.10.31.8-0.00.1-0.21.11.91.0-1.8-0.20.8-1.70.0
Social responses0.50.62.30.6-0.61.5-1.2-1.1-0.20.20.8-0.1-0.3-0.41.01.40.3-0.8-0.3-0.5-1.0-0.1
Social time1.21.63.51.1-1.3-1.11.1-0.2-1.5-1.8-0.7-1.5-1.5-1.3-1.7-0.7-1.90.8-1.6-0.60.7-1.5
Conditioned locomotion3.44.09.3-1.81.60.9-1.21.22.32.40.82.62.72.61.90.42.6-1.42.43.0-1.32.5
Cocaine response after cond. corrected0.30.31.2-0.1-0.01.1-0.6-0.20.30.50.90.40.40.41.10.50.6-0.50.30.4-0.50.3
Cocaine response after cond. not corrected0.30.31.4-0.30.11.0-0.6-0.10.40.70.70.50.60.61.20.40.7-0.30.40.2-0.50.5
Cocaine response before conditioning0.30.41.5-0.60.4-0.80.80.60.0-0.2-1.20.0-0.1-0.0-0.7-0.8-0.51.1-0.0-0.50.80.1
Saline control response0.91.22.9-1.41.20.3-0.50.61.31.70.31.51.51.41.20.11.20.01.50.2-0.21.5
Condit. Reinf. active minus inactive responses0.40.52.1-0.40.2-0.40.90.6-0.1-0.6-1.4-0.2-0.3-0.5-1.0-0.6-0.91.4-0.2-0.61.2-0.1
Condit. Reinf. active-inactive response ratio1.11.13.20.2-0.4-0.81.20.4-0.7-1.5-1.4-1.0-1.0-1.2-1.8-0.7-1.41.3-1.0-0.41.2-0.9
Condit. Reinf. active responses0.60.83.4-0.80.5-0.81.10.90.1-0.4-1.80.1-0.0-0.2-1.1-1.0-0.71.60.1-0.51.30.2
Condit. Reinf. inactive responses0.70.82.2-0.90.80.6-0.80.20.91.5-0.01.21.31.11.10.51.1-0.31.10.2-0.51.2
Condit. Reinf. lever presses2.23.08.3-0.80.4-2.52.51.6-0.3-1.5-2.9-0.6-0.8-0.7-2.7-2.2-1.82.7-0.5-0.72.5-0.5
Condit. Reinf. lever reinforcers received0.81.14.4-0.90.6-1.11.41.10.1-0.5-2.10.1-0.1-0.2-1.4-1.2-0.91.90.1-0.61.60.1
Pavlov. Cond. lever latency2.12.97.40.6-0.42.6-2.5-1.50.31.42.70.60.90.62.62.31.9-2.50.50.6-2.50.5
Pavlov. Cond. magazine entry latency1.71.94.1-1.91.8-1.61.52.01.50.4-1.41.10.81.0-0.8-1.7-0.01.71.20.71.81.2
Pavlov. Cond. change in total contacts2.23.07.7-1.41.2-2.82.62.10.4-0.7-2.80.2-0.20.2-2.1-2.6-1.22.70.3-0.22.60.3
Pavlov. Cond. index score2.22.97.5-1.61.4-2.52.42.10.7-0.5-2.60.40.00.3-1.9-2.4-1.12.70.5-0.32.60.5
Pavlov. Cond. latency score2.22.87.2-1.71.4-2.42.42.10.8-0.4-2.50.40.10.4-1.9-2.4-1.12.70.5-0.22.60.5
Pavlov. Cond. lever contacts1.82.56.2-1.00.8-2.52.31.70.1-1.0-2.5-0.2-0.4-0.1-2.2-2.2-1.42.4-0.1-0.32.3-0.1
Pavlov. Cond. magazine entry number1.11.43.01.3-1.21.7-1.6-1.6-0.80.11.6-0.6-0.3-0.51.11.70.5-1.7-0.6-0.2-1.7-0.6
Pavlov. Cond. intertrial magazine entries2.43.16.82.5-2.41.8-1.7-2.6-2.1-0.91.4-1.7-1.4-1.80.52.2-0.5-1.6-1.7-1.5-1.8-1.8
Pavlov. Cond. lever-magazine prob. diff.2.02.67.0-1.61.3-2.42.32.00.7-0.4-2.50.40.10.3-1.8-2.3-1.12.70.5-0.32.50.5
Pavlov. Cond. response bias2.12.97.2-1.51.3-2.52.52.10.6-0.6-2.60.3-0.10.3-2.0-2.5-1.22.70.4-0.12.60.3
Conditioned reinforcement - actives3.33.311.30.30.23.4-2.9-1.50.81.41.80.91.00.22.13.02.4-2.40.80.7-2.41.0
Conditioned reinforcement - inactives1.82.05.61.4-1.12.0-2.1-1.8-0.60.21.7-0.4-0.2-0.61.32.21.1-2.4-0.40.3-2.3-0.3
Conditioned locomotion2.12.66.4-0.30.72.5-2.2-0.91.11.71.71.11.10.82.22.02.4-2.01.10.8-2.01.2
Intermittent access intake day 1-15 change0.80.82.00.1-0.51.0-1.3-0.40.10.91.20.70.90.61.01.01.0-1.40.61.0-1.30.6
Intermittent access intake escalation1.01.02.30.2-0.41.1-1.5-0.60.11.11.20.71.00.71.31.21.0-1.50.70.8-1.50.6
Intermittent access intake escalation 20.30.30.70.4-0.60.7-0.8-0.5-0.40.30.50.10.3-0.00.50.80.2-0.80.10.1-0.8-0.0
Intermitt. access day 1 inactive lever presses4.14.49.53.0-2.92.1-2.4-3.1-2.2-0.52.2-1.5-1.2-1.61.32.80.5-2.7-1.6-1.1-2.7-1.6
Intermitt. access day 15 inactive lever presses0.80.92.61.1-1.01.2-1.3-1.1-0.70.31.3-0.10.1-0.10.91.30.6-1.5-0.20.2-1.6-0.2
Intermitt. access escalation Index1.21.12.21.1-1.1-0.70.5-0.7-1.4-1.2-0.6-1.3-1.5-1.2-0.9-0.2-1.10.3-1.4-1.40.1-1.2
Intermittent access day 1 total infusions0.50.51.6-0.10.90.6-0.9-0.30.80.60.90.40.30.40.70.71.3-1.10.40.8-1.10.6
Intermittent access day 15 total infusions1.61.85.60.7-0.31.7-2.1-1.20.11.01.80.40.60.31.51.91.6-2.40.40.9-2.30.4
Intermittent access terminal intake (last 3 days)1.51.66.00.9-0.41.4-1.9-1.1-0.10.61.90.20.40.11.11.81.5-2.50.21.2-2.30.2
Intermittent access total infusions1.92.16.30.8-0.31.9-2.3-1.30.11.02.10.40.50.31.62.11.7-2.50.30.9-2.40.4
Intermittent access day 1 locomotion0.20.21.20.00.50.4-0.5-0.30.40.20.40.0-0.10.10.30.41.1-0.60.10.3-0.60.4
Intermittent access day 15 total locomotion1.82.04.80.3-0.21.5-1.9-1.00.41.51.90.80.80.92.01.62.0-2.20.70.8-2.20.8
Intermittent access total locomotion1.01.12.90.3-0.11.3-1.5-0.80.30.81.50.40.40.41.31.41.6-1.70.40.7-1.60.5
Intermittent access standard deviation1.51.63.5-0.50.41.1-1.4-0.10.71.91.01.41.61.51.70.91.7-1.41.41.1-1.51.3
Cocaine induced anxiety0.60.71.6-1.21.3-0.50.51.21.20.7-0.41.00.91.00.1-0.80.30.71.00.70.71.0
Post-drug Anxiety0.10.20.9-0.40.3-0.30.10.50.60.10.40.40.50.3-0.1-0.1-0.0-0.10.41.00.20.3
Baseline Anxiety0.00.00.10.2-0.30.3-0.1-0.2-0.1-0.10.2-0.1-0.1-0.20.10.2-0.3-0.0-0.2-0.1-0.1-0.2
Lifetime Intake2.02.25.90.60.22.0-2.3-1.40.41.12.10.40.60.31.82.21.9-2.40.40.7-2.30.6
Incentive Sensitization - Responses2.72.76.12.5-2.21.2-1.3-2.2-1.9-1.51.0-1.8-1.5-2.1-0.52.0-1.0-1.3-1.8-0.9-1.2-1.9
Incentive Sensitization - Breakpoint2.62.65.82.4-2.21.1-1.3-2.1-1.9-1.51.0-1.8-1.5-2.1-0.51.9-1.0-1.3-1.8-0.7-1.2-1.9
Progressive ratio test 1 active lever presses0.50.51.50.9-0.30.4-0.8-1.0-0.3-0.31.1-0.6-0.6-0.50.10.90.6-1.2-0.50.1-1.0-0.4
Progressive ratio test 1 breakpoint0.50.61.91.0-0.40.3-0.9-1.0-0.4-0.21.2-0.6-0.6-0.50.21.00.6-1.4-0.60.1-1.2-0.4
Progressive ratio test 1 inactive lever presses0.91.02.11.4-1.40.8-1.2-1.5-1.00.01.1-0.6-0.5-0.60.81.30.4-1.3-0.6-0.6-1.4-0.6
Progressive ratio test 2 active lever presses2.72.86.12.4-1.81.5-2.0-2.5-1.5-0.91.7-1.5-1.2-1.70.12.50.1-2.2-1.5-0.5-2.0-1.4
Progressive ratio test 2 breakpoint2.32.65.82.4-1.91.1-1.6-2.3-1.6-1.11.6-1.6-1.4-1.8-0.12.2-0.1-1.9-1.6-0.5-1.7-1.6
Progressive ratio test 2 inactive lever presses1.82.14.72.2-1.70.9-1.2-2.1-1.7-1.20.9-1.6-1.5-1.8-0.21.7-0.5-1.1-1.7-1.2-1.1-1.6
Total sessions with >9 infusions2.52.87.71.6-0.92.5-2.6-2.3-0.60.42.2-0.5-0.3-0.71.62.81.3-2.5-0.5-0.3-2.4-0.2
Short access day 1 total inactive lever presses0.10.10.50.4-0.20.4-0.5-0.5-0.2-0.10.2-0.3-0.3-0.30.10.50.6-0.7-0.20.1-0.7-0.1
Short access day 10 total inactive lever presses1.61.74.91.8-2.2-0.20.1-1.4-2.2-1.0-0.2-1.5-1.4-1.3-0.20.2-1.20.3-1.5-2.1-0.2-1.7
Short access day 1 total infusions2.72.97.71.0-0.32.4-2.7-1.80.11.12.30.30.40.12.02.62.2-2.80.20.5-2.70.5
Short access day 10 total infusions1.01.13.2-0.81.60.7-0.80.11.41.20.91.00.81.01.10.51.8-1.01.00.9-0.91.2
Short access total infusions1.61.84.00.00.81.6-1.9-0.90.91.31.80.70.70.61.71.72.0-2.00.70.7-1.80.9
Short access day 1 locomotion1.11.22.60.70.01.6-1.6-1.5-0.10.71.4-0.1-0.1-0.01.61.61.5-1.6-0.1-0.6-1.60.2
Short access day 10 total locomotion0.10.10.3-0.40.60.00.30.10.3-0.0-0.5-0.0-0.3-0.0-0.2-0.20.10.50.0-0.50.40.1
Short access total locomotion0.20.20.80.10.60.8-0.4-0.60.20.10.3-0.2-0.5-0.20.50.50.9-0.3-0.1-0.6-0.40.1
Compulsive drug intake1.00.93.2-0.2-0.3-0.71.20.5-0.5-0.9-1.6-0.5-0.5-0.6-1.0-1.0-1.51.8-0.5-1.11.5-0.6
One hour access (0.3 mA shock)0.91.03.01.0-0.61.5-1.4-1.7-0.60.20.9-0.6-0.4-0.81.01.70.2-0.8-0.5-1.4-1.0-0.5
One hour access (shock baseline)2.22.66.60.9-0.52.2-2.6-1.7-0.01.22.30.30.60.22.02.41.8-2.60.30.3-2.50.4
Number of responses in last shaping day1.92.04.5-0.40.71.0-1.4-0.10.91.91.31.41.61.61.90.82.1-1.71.41.3-1.71.4
Context. condit. distance diff. score0.50.63.4-0.60.30.4-0.70.30.90.51.20.70.80.60.40.51.0-1.10.71.8-0.50.6
Locomotion velocity, session 10.91.03.0-0.40.4-1.11.50.9-0.0-0.8-1.5-0.3-0.5-0.3-1.3-1.3-1.11.7-0.2-0.51.6-0.2
Locomotion distance, session 10.50.61.9-0.30.3-1.11.30.8-0.1-0.6-1.1-0.2-0.5-0.2-0.9-1.2-0.91.4-0.2-0.41.2-0.2
Locomotion velocity, session 20.10.21.2-0.10.2-0.70.50.60.2-0.20.00.0-0.00.4-0.5-0.70.0-0.10.11.10.10.1
Locomotion distance, session 20.10.10.40.6-0.5-0.40.2-0.0-0.4-0.60.3-0.4-0.4-0.3-0.4-0.2-0.4-0.2-0.40.4-0.1-0.4
Locomotion velocity, session 30.50.62.2-0.00.1-1.21.10.90.1-1.1-0.3-0.3-0.4-0.3-1.5-1.0-0.70.4-0.31.20.8-0.3
Locomotion distance, session 30.60.72.0-0.40.2-1.41.21.00.1-0.9-0.6-0.3-0.4-0.1-1.4-1.2-0.90.8-0.30.91.0-0.3
Stereotopy head waving bouts, day 30.50.61.90.5-0.61.1-1.2-0.7-0.20.51.00.20.40.10.71.10.9-1.40.20.6-1.20.2
Stereotopy head waving duration, day 30.00.00.1-0.10.1-0.10.30.3-0.0-0.0-0.30.00.00.0-0.2-0.3-0.00.30.1-0.10.30.1
Locomotion velocity, session 70.70.71.51.1-1.20.1-0.2-0.4-0.8-1.20.7-0.9-0.7-0.9-0.80.4-0.5-1.0-1.01.2-0.6-1.0
Locomotion distance, session 71.01.34.81.0-1.21.4-1.6-1.0-0.30.01.6-0.10.2-0.30.71.70.7-2.2-0.21.5-1.9-0.2
Stereotopy head waving bouts, day 71.51.74.0-0.60.5-2.02.01.2-0.2-1.1-1.8-0.5-0.7-0.3-1.9-1.9-1.41.9-0.4-0.21.8-0.4
Stereotopy head waving duration, day 71.92.46.1-1.00.9-2.42.51.80.2-1.1-2.0-0.3-0.6-0.1-2.1-2.4-1.42.3-0.2-0.02.3-0.2
Locomotion velocity, session 80.70.83.3-1.00.9-0.50.41.21.00.60.10.91.01.30.1-0.80.8-0.21.11.80.10.9
Locomotion distance, session 80.30.43.4-0.60.4-0.30.10.80.70.10.40.50.50.6-0.2-0.30.5-0.50.51.9-0.10.4
Degree of sensitization distance3.43.48.91.6-1.72.9-2.9-2.4-0.90.72.3-0.20.2-0.52.03.01.3-2.8-0.3-0.2-2.9-0.3
Degree of sensitization stereotypy1.92.04.9-1.51.4-2.02.21.90.7-0.5-1.90.2-0.10.4-1.5-2.2-1.02.20.30.12.20.3
Condit. Reinf. active minus inactive responses1.51.73.7-0.00.2-1.61.70.7-0.4-1.4-1.9-0.9-1.2-1.0-1.9-1.3-1.61.9-0.7-1.11.8-0.8
Condit. Reinf. active-inactive response ratio0.60.71.50.7-0.6-0.40.4-0.5-0.8-1.1-0.6-1.1-1.1-1.2-1.10.0-1.10.5-1.0-1.00.4-1.0
Condit. Reinf. active responses1.92.36.3-0.81.1-1.92.31.50.3-1.1-2.4-0.3-0.7-0.5-2.0-2.0-1.32.5-0.1-0.72.5-0.2
Condit. Reinf. inactive responses1.51.83.7-1.81.9-1.21.51.91.50.5-1.61.10.81.1-0.5-1.70.21.71.20.51.71.1
Incentive salience index mean2.32.87.3-0.50.7-2.12.41.4-0.1-1.5-2.7-0.7-1.1-0.8-2.3-2.1-1.82.6-0.5-1.02.5-0.6
Condit. Reinf. lever presses2.43.39.8-1.01.2-2.12.71.80.3-1.3-3.1-0.3-0.7-0.5-2.3-2.4-1.73.1-0.2-0.82.9-0.2
Time in familiar zone, hab. session 10.20.20.6-0.60.6-0.40.50.50.3-0.0-0.70.10.10.1-0.5-0.5-0.00.70.2-0.20.70.3
Time in novel zone, hab. session 10.40.41.20.8-0.80.4-0.7-0.7-0.40.21.0-0.1-0.00.00.60.60.1-1.1-0.30.3-1.0-0.3
Total zone transitions, hab. session 10.30.41.5-0.10.3-1.20.90.6-0.0-0.6-0.8-0.3-0.3-0.2-1.1-0.9-0.70.7-0.20.10.8-0.2
Total locomotion distance, hab. session 10.10.10.50.00.2-0.70.10.30.20.10.20.20.30.2-0.3-0.20.1-0.20.30.5-0.00.2
Locomotion velocity, hab. session 10.30.41.0-0.60.8-1.00.40.80.80.4-0.20.70.70.6-0.3-0.60.40.20.70.70.30.7
Time in familiar zone, hab. session 21.51.63.3-1.41.30.6-0.70.61.51.80.51.61.61.61.50.31.8-0.41.60.8-0.51.6
Time in novel zone, hab. session 20.91.02.11.2-1.1-0.40.5-0.5-1.2-1.50.0-1.3-1.3-1.2-1.1-0.1-1.30.1-1.3-0.30.2-1.3
Total zone transitions, hab. session 21.11.43.6-1.21.2-1.91.61.80.80.0-1.40.70.50.8-1.1-1.8-0.41.30.70.81.40.7
Total locomotion distance, hab. session 20.70.92.8-1.01.0-1.71.01.40.80.5-0.70.90.81.2-0.4-1.40.30.50.91.10.60.8
Locomotion velocity, hab. session 20.70.93.1-0.91.0-1.81.21.40.70.4-0.90.80.71.1-0.6-1.50.10.70.80.90.80.7
Novel to familiar place preference ratio0.80.92.60.9-0.91.5-1.4-1.1-0.5-0.01.1-0.3-0.1-0.30.71.40.7-1.6-0.30.7-1.4-0.3
Novelty place preference0.80.82.70.9-0.91.4-1.3-1.0-0.5-0.11.1-0.3-0.1-0.30.61.30.6-1.6-0.40.9-1.4-0.3
Time in novel zone, NPP test0.70.82.50.9-0.81.4-1.2-0.9-0.4-0.11.1-0.3-0.1-0.20.61.30.6-1.6-0.30.9-1.3-0.3
Total zone transitions, NPP test0.50.72.0-0.40.6-1.41.30.90.2-0.5-1.1-0.1-0.20.0-1.0-1.3-0.81.3-0.0-0.21.3-0.0
Total locomotion distance, NPP test0.30.51.11.1-1.0-0.1-0.1-0.8-1.0-0.60.1-0.9-0.8-0.8-0.20.3-0.6-0.2-0.9-0.8-0.3-0.8
Locomotion velocity, NPP test0.30.51.21.1-1.0-0.3-0.0-0.7-1.1-0.60.0-0.9-0.8-0.8-0.30.2-0.6-0.2-0.9-0.8-0.2-0.8
Pavlov. Cond. lever latency1.31.65.6-0.0-0.10.9-1.5-0.40.61.32.40.81.11.01.51.11.6-2.10.81.5-1.70.8
Pavlov. Cond. magazine entry latency0.20.31.3-0.30.3-0.20.40.10.1-0.2-1.2-0.1-0.2-0.4-0.4-0.2-0.51.0-0.1-0.90.8-0.1
Pavlov. Cond. change in total contacts0.90.93.8-0.10.2-0.51.10.1-0.4-0.6-1.9-0.5-0.7-0.5-0.6-0.9-1.01.7-0.5-1.81.4-0.5
Pavlov. Cond. index score1.72.26.9-0.30.3-1.31.90.7-0.5-1.3-2.6-0.8-1.1-0.9-1.7-1.6-1.82.5-0.8-1.72.2-0.8
Pavlov. Cond. latency score1.72.26.9-0.10.2-1.11.80.5-0.6-1.4-2.6-0.9-1.2-1.1-1.7-1.4-1.82.5-0.9-1.82.1-0.9
Pavlov. Cond. lever contacts1.51.86.6-0.20.3-1.01.70.7-0.4-1.3-2.6-0.7-1.0-1.0-1.6-1.3-1.62.3-0.7-1.42.0-0.7
Pavlov. Cond. magazine entry number0.81.03.10.1-0.20.9-1.2-0.30.40.81.80.60.80.71.10.91.3-1.70.61.4-1.50.6
Pavlov. Cond. intertrial magazine entries0.91.02.7-1.01.1-1.61.51.40.7-0.2-1.20.40.10.4-1.1-1.5-0.31.50.50.21.50.4
Pavlov. Cond. lever-magazine prob. diff.1.92.46.9-0.20.2-1.52.00.7-0.6-1.4-2.6-0.9-1.2-1.0-1.8-1.6-1.92.5-0.9-1.72.2-0.9
Pavlov. Cond. response bias1.62.07.0-0.70.8-1.51.91.20.1-1.0-2.6-0.3-0.6-0.5-1.7-1.7-1.52.4-0.3-1.02.2-0.3
Bone: apparent density0.10.21.00.6-0.40.2-0.5-0.4-0.3-0.10.6-0.2-0.1-0.10.10.50.4-1.0-0.20.6-0.8-0.2
Bone surface0.10.20.60.3-0.20.4-0.6-0.5-0.10.40.70.10.20.20.60.50.5-0.70.00.0-0.70.1
Bone volume0.10.20.60.4-0.30.2-0.5-0.5-0.20.20.7-0.10.00.10.50.40.3-0.8-0.10.2-0.7-0.1
Bone: connectivity density0.40.61.80.2-0.10.9-1.1-0.30.30.51.00.40.60.30.71.01.1-1.30.41.2-1.20.4
Bone: cortical apparent density0.70.92.10.2-0.2-1.11.10.3-0.5-1.1-0.7-0.8-1.0-1.0-1.4-0.8-1.31.2-0.8-0.91.3-0.8
Bone: cortical area0.00.10.20.2-0.3-0.20.1-0.2-0.2-0.30.4-0.4-0.4-0.3-0.10.0-0.40.0-0.4-0.3-0.0-0.4
Bone: cortical porosity2.62.95.3-2.22.1-1.51.02.32.11.4-0.72.01.92.20.1-1.61.20.72.12.00.92.0
Bone: cortical porosity2.62.85.2-2.22.1-1.41.02.32.11.3-0.81.91.82.10.1-1.61.20.82.01.91.02.0
Bone: cortical thickness0.10.20.4-0.20.1-0.70.60.30.0-0.4-0.1-0.3-0.4-0.2-0.6-0.6-0.60.7-0.2-0.30.6-0.3
Bone: cortical thickness0.40.51.3-0.40.2-1.01.10.80.1-0.8-0.7-0.3-0.5-0.2-1.0-1.1-0.70.9-0.30.31.0-0.3
Bone: cortical tissue density0.70.92.10.2-0.2-1.11.10.3-0.5-1.2-0.8-0.8-1.0-1.0-1.5-0.8-1.31.2-0.8-0.91.3-0.8
Bone: elastic displacement1.21.33.2-0.90.90.6-0.70.41.11.60.51.31.41.61.40.21.8-0.81.41.2-0.71.4
Bone: elastic work0.30.40.9-0.80.8-0.60.30.80.70.7-0.20.70.71.00.3-0.60.80.10.80.50.20.8
Bone: endosteal estimation0.20.41.60.6-0.50.6-1.0-0.6-0.10.30.90.10.30.10.70.90.6-1.30.10.5-1.20.0
Bone: endosteal perimeter0.51.02.50.3-0.31.4-1.5-0.70.30.91.20.60.80.51.41.31.1-1.60.50.9-1.60.5
Bone: final force0.30.62.2-0.90.8-1.50.91.20.80.0-0.70.40.40.5-0.7-1.00.10.50.50.90.70.5
Bone: final moment0.50.92.7-1.11.0-1.71.11.41.00.1-0.80.60.50.7-0.8-1.30.10.70.70.90.90.7
Bone: marrow area0.20.51.80.5-0.50.7-1.1-0.7-0.10.41.00.20.30.10.81.00.7-1.30.10.6-1.20.1
Bone: maximum diameter0.40.71.90.4-0.41.0-1.2-0.80.00.71.40.30.40.41.21.00.7-1.30.20.4-1.30.2
Bone: maximum force0.50.91.7-1.21.1-1.30.61.31.20.6-0.40.90.91.1-0.2-1.00.60.31.01.10.41.0
Bone: maximum moment0.61.12.3-1.31.3-1.50.91.51.30.6-0.71.00.91.1-0.4-1.20.40.61.01.10.81.0
Bone: minimum diameter0.10.20.80.4-0.40.3-0.6-0.5-0.20.30.9-0.00.10.10.60.50.3-0.7-0.1-0.1-0.7-0.1
Bone: periosteal estimation0.20.51.30.8-0.80.6-1.0-0.9-0.40.11.1-0.2-0.1-0.30.61.00.3-1.1-0.30.1-1.1-0.3
Bone: periosteal perimeter0.20.30.80.7-0.70.8-0.8-0.8-0.30.10.8-0.2-0.1-0.20.70.80.1-0.8-0.3-0.0-0.9-0.3
Bone: post-yield work0.30.40.9-0.60.6-0.3-0.10.50.70.80.10.80.90.90.5-0.20.6-0.30.80.8-0.30.8
Bone: stiffness0.10.10.70.3-0.3-0.80.3-0.0-0.3-0.40.1-0.4-0.3-0.3-0.5-0.2-0.5-0.1-0.40.1-0.0-0.4
Bone: tissue strength0.10.10.90.1-0.20.3-0.5-0.30.10.31.00.10.2-0.00.40.50.3-0.50.1-0.1-0.50.1
Bone: trabecular number0.30.51.90.2-0.10.9-0.9-0.20.30.30.80.40.50.30.50.80.8-1.20.41.4-1.00.3
Bone: trabecular spacing0.20.30.8-0.90.7-0.40.40.80.70.4-0.20.60.50.60.0-0.50.10.50.60.40.50.6
Bone: trabecular thickness0.30.41.40.0-0.0-1.21.00.4-0.3-0.6-0.6-0.5-0.6-0.3-0.9-0.9-0.60.6-0.4-0.30.7-0.4
Bone: trabecular tissue density0.40.61.10.3-0.3-0.91.00.2-0.6-0.9-0.5-0.8-0.8-0.7-1.0-0.8-1.01.0-0.7-0.91.0-0.7
Breakpoint value in progressive ratio session0.00.00.3-0.00.1-0.00.00.00.00.20.00.1-0.10.20.2-0.10.5-0.20.10.10.00.1
Distance traveled before self-admin0.70.72.0-1.21.3-0.2-0.10.81.40.80.11.00.90.90.2-0.21.0-0.01.01.0-0.11.1
Distance traveled after self-admin1.31.43.0-1.01.21.0-0.80.61.61.20.81.41.31.21.10.51.7-1.01.41.7-1.01.4
Delta time in closed arm before/after self-admin0.30.31.0-0.20.3-0.0-0.40.10.50.50.80.50.70.60.50.20.7-0.80.51.0-0.40.4
Delta time in open arm before/after self-admin3.53.37.22.5-2.61.8-1.7-2.7-1.9-1.01.6-1.7-1.4-2.00.72.3-0.7-1.4-1.8-1.7-1.5-1.8
Diff in mean of infusions in LGA sessions0.30.31.4-0.10.5-0.1-0.30.10.50.60.60.30.20.80.6-0.01.2-1.00.30.9-0.40.5
Extinction: sum of active levers before priming0.10.10.4-0.00.10.4-0.4-0.10.20.30.10.10.10.10.20.40.7-0.40.20.1-0.40.2
Active lever presses in extinction session 60.50.42.0-0.50.20.1-0.30.60.60.60.30.80.90.80.30.00.9-0.60.81.4-0.70.7
Delta distance traveled before/after self-admin0.60.72.11.0-0.91.5-1.0-1.1-0.6-0.20.9-0.5-0.4-0.60.71.20.1-1.0-0.6-0.2-0.9-0.5
Delta ambulatory time before/after self-admin0.40.41.60.6-0.51.2-0.9-0.7-0.30.20.6-0.1-0.1-0.20.80.90.4-0.9-0.2-0.0-0.9-0.1
Time in closed arm before self-admin0.91.02.9-1.01.0-1.71.41.40.6-0.3-1.10.30.00.5-1.3-1.6-0.51.20.30.71.10.4
Time in closed arm after self-admin1.51.64.0-1.51.6-2.01.71.81.10.0-1.30.60.40.9-1.1-2.0-0.41.50.60.71.50.7
Time in open arm before self-admin1.71.83.7-1.91.9-0.40.51.71.81.2-0.41.61.51.70.4-1.01.20.41.61.60.51.6
Time in open arm after self-admin1.82.04.22.0-1.91.4-1.4-2.0-1.4-0.91.5-1.3-1.1-1.60.41.9-0.1-1.6-1.4-0.8-1.3-1.4
Sum of active levers in priming session hrs 5-60.10.10.30.4-0.50.10.1-0.1-0.5-0.6-0.4-0.5-0.6-0.5-0.50.1-0.30.1-0.5-0.10.0-0.4
Time to tail flick, vehicle, before self-admin1.11.12.8-1.31.4-0.40.11.21.60.8-0.11.31.11.0-0.1-0.31.00.11.31.70.11.4
Time to tail flick, vehicle, after self-admin0.20.30.8-0.40.4-0.40.10.50.40.60.40.50.80.90.4-0.50.2-0.20.60.70.20.5
Time to tail flick, test, before self-admin0.60.51.7-0.70.7-1.31.01.00.5-0.2-0.80.20.20.2-0.9-1.0-0.51.00.30.21.10.2
Time to tail flick, test, after self-admin0.60.61.90.2-0.31.4-1.3-0.60.10.70.80.50.80.21.01.20.5-0.80.40.3-1.20.4
Delta time to tail flick, vehicle, before/after SA0.80.72.01.3-1.30.2-0.3-1.1-1.4-0.40.7-1.1-0.7-0.60.40.3-0.7-0.7-1.0-0.9-0.4-1.1
Delta time to tail flick, test, before/after SA0.80.73.10.3-0.61.8-1.3-0.6-0.10.60.70.40.60.10.91.40.6-0.90.30.4-1.20.4
Ambulatory time before self-admin1.01.02.7-1.51.6-0.90.71.41.50.6-0.61.00.81.0-0.3-1.00.50.81.00.90.71.0
Ambulatory time after self-admin1.61.83.9-1.81.90.00.11.52.01.2-0.11.71.41.60.6-0.61.5-0.11.62.0-0.11.7
Total heroin consumption0.60.71.80.1-0.1-0.30.90.0-0.6-0.8-1.3-0.8-1.0-0.8-0.9-0.5-0.81.3-0.8-1.31.1-0.6
Area under the delay curve1.81.94.4-1.81.5-1.71.72.01.10.7-1.51.11.01.4-0.6-2.1-0.31.81.10.41.61.1
Delay disc. indifference point, 0s delay0.30.31.0-0.60.6-0.30.00.60.60.70.20.71.00.80.2-0.30.4-0.00.70.80.10.7
Delay disc. indifference point, 16s delay1.41.43.0-1.71.3-0.70.61.41.21.4-0.61.51.61.70.5-1.20.50.81.50.50.61.5
Delay disc. indifference point, 2s delay1.11.22.8-1.41.1-1.41.31.71.00.4-1.21.00.81.0-0.6-1.5-0.21.30.90.61.20.8
Delay disc. indifference point, 24s delay0.30.31.1-0.60.3-0.70.70.60.10.3-0.60.20.30.4-0.2-0.9-0.51.10.3-0.60.70.3
Delay disc. indifference point, 4s delay2.22.35.4-1.81.8-1.72.02.31.30.2-1.81.00.71.2-1.0-2.3-0.31.81.10.92.01.0
Delay disc. indifference point, 8s delay1.01.03.0-1.00.9-1.51.51.30.30.3-1.30.50.40.8-0.6-1.7-0.61.50.5-0.21.40.5
Delay discount exponential model param2.12.25.71.8-1.52.0-2.0-2.2-0.9-0.41.9-0.9-0.8-1.21.02.40.6-2.1-1.0-0.3-1.9-0.9
Delay discount hyperbolic model param2.32.46.01.9-1.62.0-2.1-2.3-1.1-0.51.9-1.1-0.8-1.30.92.40.5-2.1-1.1-0.4-2.0-1.0
Fecal boli incidents, locomotor time 12.02.23.70.5-0.3-1.81.90.3-1.1-1.5-1.7-1.3-1.7-1.1-1.9-1.6-1.71.9-1.2-1.91.9-1.2
Change in fecal boli incidents, locomotor task1.31.23.90.3-0.31.2-1.5-0.40.30.71.50.61.10.61.21.20.9-2.00.51.8-1.80.5
Time >=10cm from walls, locomotor time 10.50.51.6-0.91.0-0.50.20.91.00.3-0.10.71.00.6-0.5-0.40.40.00.71.30.30.7
Bouts of movement, locomotor time 10.50.61.30.5-0.3-0.90.8-0.0-0.8-0.9-0.9-0.9-0.7-0.6-0.9-0.7-1.10.6-0.8-0.50.8-0.8
Total resting periods, locomotor time 10.60.61.50.6-0.5-0.90.7-0.2-0.9-1.0-0.8-1.0-0.8-0.7-0.9-0.6-1.20.5-1.0-0.70.7-0.9
Rest time, locomotor task time 14.14.59.61.2-1.2-1.92.1-0.3-2.1-2.6-2.0-2.3-2.4-2.1-2.6-1.5-3.12.1-2.3-2.41.9-2.3
Distance moved, locomotor task time 12.83.06.2-1.31.21.5-1.60.42.02.21.52.12.01.82.11.12.5-1.52.01.9-1.42.0
Vertical activity count, locomotor time 15.35.510.7-2.11.91.5-1.50.92.63.31.33.02.93.03.00.63.3-1.52.92.3-1.42.9
Time >=10cm from walls, locomotor time 21.11.25.0-0.91.00.1-0.41.01.31.00.51.41.51.30.30.01.1-0.81.32.2-0.61.3
Bouts of movement, locomotor time 20.30.30.70.6-0.5-0.30.4-0.4-0.8-0.6-0.4-0.8-0.7-0.5-0.2-0.2-0.60.4-0.7-0.80.3-0.6
Total resting periods, locomotor time 20.80.91.70.9-0.8-0.70.7-0.5-1.2-1.1-0.7-1.3-1.2-1.0-0.8-0.5-1.10.7-1.2-1.30.6-1.1
Rest time, locomotor task time 23.64.26.91.1-1.2-1.82.0-0.3-2.1-2.4-2.4-2.3-2.4-2.0-2.4-1.5-2.62.0-2.3-2.41.8-2.1
Distance moved, locomotor task time 22.32.75.2-1.61.70.7-0.81.12.02.20.92.32.22.01.70.22.1-0.52.21.6-0.62.2
Vertical activity count, locomotor time 25.66.111.4-2.62.61.3-1.11.63.13.40.93.43.43.22.70.22.9-0.63.32.1-0.63.2
Weight adjusted by age1.01.13.0-0.20.1-1.51.50.8-0.4-1.1-1.4-0.6-0.9-0.6-1.7-1.3-1.01.5-0.6-0.31.3-0.6
Seeking ratio, delayed vs. immediate footshock1.82.14.6-1.01.21.9-1.40.11.71.60.91.61.41.42.01.02.2-1.11.51.4-1.11.5
Locomotion in novel chamber0.50.71.9-0.80.5-1.21.31.20.4-0.1-1.00.20.20.4-0.7-1.4-0.61.20.30.21.30.2
Locomotion in novel chamber post-restriction0.81.06.2-0.50.30.0-0.31.00.90.70.71.11.21.20.4-0.10.9-0.91.12.5-0.71.0
Progressive ratio0.20.20.6-0.50.4-0.10.20.40.30.6-0.10.40.50.80.6-0.50.10.30.40.10.40.4
Food seeking constrained by brief footshock0.30.41.80.6-0.60.6-0.5-1.1-0.60.10.4-0.4-0.5-0.40.70.6-0.2-0.2-0.5-1.4-0.4-0.5
Seeking ratio, punishment vs. effort0.00.00.10.1-0.2-0.1-0.0-0.2-0.2-0.2-0.2-0.1-0.4-0.4-0.30.1-0.10.1-0.2-0.4-0.2-0.2
Run reversals in cocaine runway, females0.90.91.9-0.60.51.2-1.00.21.30.71.10.91.10.60.90.91.2-1.01.01.4-0.40.8
Run reversals in cocaine runway, males0.70.71.9-1.11.1-1.10.91.00.80.2-0.90.60.30.4-0.5-1.0-0.41.40.6-0.31.10.5
Latency to leave start box in cocaine runway0.40.51.00.9-0.81.0-0.8-1.0-0.5-0.30.9-0.5-0.4-0.50.41.00.1-0.9-0.5-0.2-0.7-0.6
Latency to leave start box in cocaine runway, F1.01.12.51.3-1.31.3-1.2-1.6-1.0-0.41.1-0.8-0.7-0.90.61.40.1-1.0-0.9-0.8-1.0-0.9
Latency to leave start box in cocaine runway, M0.60.61.40.7-0.7-0.30.4-0.4-0.8-1.0-0.2-1.0-0.9-0.9-0.8-0.1-1.20.3-1.0-0.80.7-1.1
Cd content in liver0.80.92.21.1-1.20.9-0.8-1.5-1.1-0.21.0-0.9-0.8-0.80.61.0-0.5-0.6-0.9-1.3-0.7-0.9
Co content in liver0.20.20.4-0.40.6-0.60.40.50.40.3-0.50.40.30.60.1-0.70.30.20.40.30.40.4
Cu content in liver1.11.33.60.6-0.7-1.51.30.2-1.0-1.6-0.9-1.2-1.1-1.1-1.9-1.0-1.61.0-1.2-0.41.0-1.2
Fe content in liver0.40.41.11.0-1.00.8-0.4-0.6-0.8-0.70.7-0.7-0.5-0.9-0.20.7-0.4-0.6-0.70.1-0.6-0.7
K content in liver0.90.95.5-0.20.4-0.2-0.60.50.90.60.90.91.10.8-0.00.41.0-1.40.92.4-0.80.9
Mg content in liver1.01.03.60.2-0.00.7-1.4-0.30.50.81.40.71.00.60.61.11.1-1.90.71.7-1.50.7
Mn content in liver0.81.01.9-0.40.40.8-1.2-0.00.81.01.11.01.30.70.81.01.3-1.41.01.3-1.10.9
Na content in liver1.61.74.7-1.31.1-1.91.72.21.1-0.5-1.60.60.40.5-1.7-1.8-0.41.20.61.71.60.6
Rb content in liver2.63.27.80.4-0.22.2-2.6-1.10.61.82.31.11.61.02.32.22.3-2.81.11.3-2.61.0
Se content in liver1.61.95.40.3-0.41.8-2.0-1.10.31.42.30.71.00.72.11.71.5-1.90.60.5-2.00.7
Sr content in liver2.11.93.61.6-1.70.7-0.3-1.5-1.8-1.50.3-1.8-1.7-1.9-0.60.8-1.4-0.1-1.8-1.5-0.2-1.8
Zn content in liver0.80.92.9-1.01.1-1.70.91.20.80.6-1.00.80.61.0-0.4-1.30.30.80.90.40.80.9