Dleu7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000009181 0.67 0.09 0.0e+00 0.5 0.54 0.53 0.52 3.6e-30 1.8e-33 1.4e-32 7.5e-32
2 Brain gene expression ENSRNOG00000009181 0.52 0.1 0.0e+00 0.51 0.54 0.54 0.54 5.1e-55 1.1e-58 2.4e-58 2.5e-58
3 IL gene expression ENSRNOG00000009181 0.44 0.16 7.0e-06 0.1 0.12 0.04 0.09 2.2e-03 9.2e-04 5.0e-02 3.0e-03
4 LHb gene expression ENSRNOG00000009181 0.54 0.16 1.0e-10 0.13 0.28 0.26 0.25 5.9e-04 1.9e-07 9.2e-07 1.3e-06
5 NAcc gene expression ENSRNOG00000009181 0.57 0.13 0.0e+00 0.44 0.43 0.44 0.44 1.2e-35 4.2e-35 4.7e-36 4.9e-36
6 OFC gene expression ENSRNOG00000009181 0.67 0.16 2.9e-09 0.19 0.17 0.15 0.16 2.3e-05 6.3e-05 2.6e-04 1.1e-04
7 PL alternative TSS ENSRNOT00000065838 0.03 0.03 6.4e-03 0.01 0.02 0.01 0.01 6.8e-02 1.2e-02 3.3e-02 4.5e-02
8 PL alternative TSS ENSRNOT00000076969 0.04 0.03 4.3e-03 0.01 0.02 0.01 0.01 5.5e-02 7.9e-03 2.7e-02 3.8e-02
9 PL gene expression ENSRNOG00000009181 0.63 0.12 0.0e+00 0.39 0.52 0.52 0.52 4.7e-31 1.4e-45 3.1e-45 5.5e-45
10 PL isoform ratio ENSRNOT00000065838 0.03 0.02 8.2e-03 0.01 0.02 0.01 0.01 9.2e-02 1.9e-02 7.1e-02 4.4e-02
11 PL isoform ratio ENSRNOT00000076969 0.03 0.02 9.1e-03 0.01 0.02 0.01 0.01 9.3e-02 2.0e-02 6.0e-02 4.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.20.71.8-1.1-0.8-0.3-0.8-1.4-0.9-0.60.5-0.5-0.80.7
BMI without tail0.10.10.40.10.30.60.3-0.10.30.4-0.50.50.3-0.4
Body weight0.62.63.6-1.4-1.6-1.9-1.7-1.7-1.4-1.61.6-1.5-1.71.7
Epididymis fat weight0.20.41.30.80.8-0.30.21.01.10.10.0-0.20.2-0.2
Glucose0.20.20.8-0.9-0.40.2-0.5-0.8-0.6-0.20.10.0-0.40.4
Heart weight0.20.30.9-0.7-0.8-0.2-0.3-1.0-0.9-0.40.4-0.3-0.40.4
Left kidney weight2.88.111.1-3.3-2.8-1.8-3.1-3.0-2.8-2.82.7-2.7-3.02.9
Right kidney weight4.312.314.6-3.8-3.6-2.6-3.6-3.6-3.4-3.63.5-3.5-3.63.6
Tail length0.10.20.70.0-0.3-0.8-0.40.20.1-0.60.6-0.7-0.40.5
Length with tail0.20.62.5-0.0-0.4-1.6-0.80.1-0.1-0.91.0-0.9-0.80.8
Length without tail0.61.32.6-0.8-1.0-1.6-1.2-0.7-0.8-1.21.3-1.2-1.21.2
Liver weight, left3.96.37.9-2.6-2.8-2.4-2.5-2.4-2.7-2.52.4-2.1-2.62.5
Liver weight, right0.10.20.3-0.3-0.5-0.5-0.4-0.2-0.3-0.50.5-0.5-0.50.5
Parametrial fat weight3.26.39.53.12.81.42.52.93.02.3-2.22.12.5-2.4
Retroperitoneal fat weight0.20.61.81.01.10.40.71.01.30.5-0.40.10.7-0.6
Intraocular pressure0.81.22.01.20.91.11.41.00.91.0-1.00.71.3-1.2
Extensor digitorum longus weight6.225.029.6-4.7-5.0-5.4-5.3-4.3-4.8-5.15.1-4.6-5.35.3
Soleus weight0.51.42.2-1.2-1.4-1.0-1.0-1.5-1.5-1.11.0-0.9-1.11.0
Tibialis anterior weight6.221.524.5-4.5-4.7-4.9-5.0-4.5-4.7-4.64.5-3.9-4.94.8
Tibia length0.41.13.1-1.3-1.2-0.6-1.0-1.8-1.3-0.70.6-0.3-1.00.9
Number of licking bursts0.10.10.2-0.3-0.4-0.2-0.2-0.4-0.5-0.20.10.1-0.20.2
Food consumed during 24 hour testing period0.20.20.5-0.6-0.6-0.3-0.4-0.6-0.7-0.40.4-0.3-0.50.4
Times rat made contact with spout0.10.10.6-0.1-0.3-0.8-0.3-0.2-0.4-0.20.20.2-0.30.3
Mean time between licks in bursts1.31.82.90.91.21.71.40.61.01.5-1.61.61.4-1.5
Mean num. licks in bursts0.00.00.20.1-0.1-0.5-0.1-0.2-0.1-0.10.2-0.1-0.10.1
Std. dev. time between licks in bursts1.51.82.41.51.31.21.51.51.41.3-1.21.01.5-1.4
Water consumed over 24 hours0.50.51.0-0.5-0.9-1.0-0.6-0.6-0.8-0.70.7-0.5-0.70.7
Indifference point 0 sec0.30.51.31.20.4-0.50.70.40.60.6-0.60.90.6-0.6
Indifference point AUC0.20.20.7-0.10.30.80.2-0.10.10.5-0.60.80.3-0.4
Indifference point function ln k0.60.82.0-0.4-0.9-1.4-0.8-0.5-0.8-1.01.0-1.0-0.80.9
Indifference point function log k0.60.82.0-0.4-0.9-1.4-0.8-0.5-0.8-1.01.0-1.0-0.80.9
Delay discounting total patch changes 0 sec0.10.21.10.80.0-1.00.30.00.20.2-0.20.50.2-0.2
Delay discounting total patch changes 12 sec0.10.10.3-0.1-0.4-0.5-0.1-0.6-0.40.1-0.10.5-0.10.1
Delay discounting total patch changes 18 sec0.00.00.30.2-0.1-0.6-0.1-0.0-0.1-0.00.00.2-0.10.1
Delay discounting total patch changes 24 sec0.20.31.4-0.1-0.5-1.2-0.5-0.3-0.4-0.40.4-0.2-0.50.5
Delay discounting total patch changes 6 sec0.20.30.90.40.30.20.5-0.10.30.6-0.71.00.5-0.5
Delay discounting time to switch 0 sec0.20.21.20.50.60.30.31.10.70.2-0.10.00.3-0.2
Delay discounting water rate 0 sec1.01.62.5-1.0-1.4-1.6-1.1-1.5-1.4-1.21.2-1.0-1.21.2
Delay discounting water rate 12 sec4.36.59.5-2.0-2.7-3.1-2.4-2.1-2.5-2.72.7-2.5-2.52.6
Delay discounting water rate 18 sec6.89.010.3-2.8-3.2-3.2-3.0-3.1-3.2-2.92.9-2.6-3.03.0
Delay discounting water rate 24 sec1.62.23.9-1.0-1.5-2.0-1.4-1.1-1.4-1.61.6-1.6-1.41.5
Delay discounting water rate 6 sec3.14.57.6-1.5-2.3-2.8-2.0-1.7-2.0-2.22.2-2.1-2.12.2
Locomotor activity3.35.29.3-1.7-2.4-3.0-2.3-1.9-2.1-2.42.4-2.1-2.42.4
Locomotor testing distance0.40.63.1-0.0-0.7-1.7-0.6-0.4-0.3-0.70.7-0.5-0.70.7
Locomotor testing rearing0.10.10.30.1-0.5-0.60.1-0.6-0.40.0-0.10.20.0-0.0
Light reinforcement 10.20.51.0-0.4-0.5-1.0-0.8-0.3-0.5-0.70.7-0.6-0.70.8
Light reinforcement 20.81.01.91.31.20.51.01.31.40.9-0.80.71.0-0.9
Reaction time number correct0.10.20.50.40.20.40.50.10.10.5-0.50.70.4-0.5
Reaction time mean minus median0.40.51.3-0.7-0.6-0.4-0.7-0.4-0.5-0.90.9-1.1-0.70.7
Reaction time mean minus median AUC0.10.20.4-0.6-0.40.3-0.3-0.5-0.4-0.30.3-0.5-0.30.3
Reaction time num false alarms0.10.10.3-0.4-0.2-0.4-0.5-0.1-0.2-0.30.3-0.2-0.40.4
Reaction time num false alarms AUC0.20.30.6-0.7-0.4-0.6-0.8-0.4-0.4-0.50.5-0.4-0.70.6
Reaction time trials correct on left0.10.20.50.40.20.40.50.10.10.5-0.50.70.4-0.5
Reaction time trials on left0.20.30.60.40.30.50.60.10.10.6-0.60.80.5-0.6
Reaction time mean0.10.10.30.30.40.30.30.50.40.1-0.0-0.30.2-0.2
Reaction time mean AUC0.10.10.30.50.40.40.40.60.50.2-0.1-0.20.4-0.3
Median of all reaction times0.20.20.50.60.60.40.50.70.60.3-0.2-0.10.4-0.4
Reaction time omissions1.62.24.01.01.42.01.60.61.21.6-1.71.51.6-1.6
Reaction time false alarm rate0.30.40.8-0.7-0.4-0.6-0.9-0.5-0.4-0.60.6-0.5-0.70.7
Reaction time premature initiation rate0.60.81.7-0.8-0.6-0.7-1.0-0.0-0.5-1.01.1-1.3-1.01.0
Reaction time premature initiations0.20.20.5-0.4-0.3-0.3-0.50.2-0.3-0.60.6-0.7-0.50.5
Std. dev. reaction times0.00.10.30.10.30.50.20.30.30.1-0.0-0.30.2-0.2
Reaction time trials completed0.20.30.60.40.30.50.60.10.10.6-0.60.80.5-0.6
Reaction time trials AUC0.20.30.70.50.30.40.60.20.20.6-0.60.80.6-0.6
Social response proportion2.52.83.81.51.91.91.61.41.81.7-1.61.41.7-1.7
Social responses1.01.31.81.01.01.31.30.71.01.2-1.21.01.2-1.2
Social time0.30.40.8-0.9-0.5-0.1-0.7-0.9-0.8-0.40.3-0.1-0.60.6
Conditioned locomotion0.50.62.91.10.9-0.40.31.71.20.00.1-0.20.3-0.2
Cocaine response after cond. corrected0.20.20.40.70.60.20.50.40.60.4-0.40.40.5-0.5
Cocaine response after cond. not corrected0.20.20.50.70.4-0.00.50.40.60.3-0.30.30.4-0.4
Cocaine response before conditioning0.60.71.1-0.9-1.0-0.7-0.8-0.7-0.9-0.90.9-0.8-0.90.9
Saline control response0.10.10.30.4-0.2-0.50.20.4-0.0-0.20.3-0.50.00.0
Condit. Reinf. active minus inactive responses0.91.11.9-1.4-1.2-0.1-0.9-1.1-1.2-1.01.0-1.1-1.00.9
Condit. Reinf. active-inactive response ratio1.11.12.8-1.7-1.10.2-1.1-1.2-1.2-0.90.9-1.0-1.01.0
Condit. Reinf. active responses1.21.72.3-1.5-1.5-0.5-1.2-1.2-1.4-1.31.3-1.4-1.31.3
Condit. Reinf. inactive responses0.10.20.50.70.2-0.00.50.70.50.1-0.1-0.00.4-0.3
Condit. Reinf. lever presses4.15.77.9-2.8-2.6-1.4-2.4-2.4-2.7-2.42.3-2.2-2.42.4
Condit. Reinf. lever reinforcers received1.72.43.4-1.8-1.8-0.7-1.4-1.4-1.7-1.61.6-1.7-1.51.5
Pavlov. Cond. lever latency3.95.37.02.62.41.62.42.32.52.3-2.22.12.4-2.3
Pavlov. Cond. magazine entry latency3.13.55.0-1.8-1.8-1.7-1.9-1.4-1.8-2.02.1-2.2-1.91.9
Pavlov. Cond. change in total contacts4.86.77.5-2.6-2.7-2.3-2.6-2.3-2.7-2.72.6-2.5-2.72.7
Pavlov. Cond. index score4.96.47.3-2.6-2.7-2.1-2.5-2.3-2.7-2.62.6-2.6-2.62.6
Pavlov. Cond. latency score4.96.37.1-2.6-2.7-2.1-2.5-2.3-2.6-2.62.6-2.6-2.52.5
Pavlov. Cond. lever contacts3.65.05.9-2.4-2.4-1.8-2.3-2.1-2.4-2.32.2-2.1-2.32.3
Pavlov. Cond. magazine entry number2.53.03.61.71.81.51.81.41.71.8-1.81.91.8-1.8
Pavlov. Cond. intertrial magazine entries3.54.56.11.82.02.42.21.31.72.3-2.42.52.2-2.2
Pavlov. Cond. lever-magazine prob. diff.4.66.06.9-2.5-2.6-2.0-2.4-2.2-2.6-2.52.5-2.5-2.52.5
Pavlov. Cond. response bias4.76.57.2-2.6-2.7-2.1-2.6-2.3-2.7-2.62.6-2.6-2.62.6
Conditioned reinforcement - actives5.45.39.12.02.33.02.52.72.02.1-2.11.32.4-2.4
Conditioned reinforcement - inactives4.14.75.32.02.32.22.12.11.92.2-2.22.12.2-2.2
Conditioned locomotion2.42.94.51.81.81.71.92.11.61.6-1.51.01.8-1.8
Intermittent access intake day 1-15 change1.11.11.81.31.20.81.01.31.30.9-0.90.81.0-1.0
Intermittent access intake escalation1.61.52.31.51.40.81.21.41.51.1-1.01.01.2-1.2
Intermittent access intake escalation 20.60.60.70.80.80.70.80.60.80.7-0.70.70.7-0.7
Intermitt. access day 1 inactive lever presses7.98.511.52.72.92.82.92.32.53.2-3.23.43.0-3.1
Intermitt. access day 15 inactive lever presses1.82.02.21.51.51.21.41.41.51.4-1.41.51.4-1.4
Intermitt. access escalation Index0.10.10.3-0.2-0.20.1-0.0-0.4-0.40.2-0.30.60.0-0.1
Intermittent access day 1 total infusions0.50.61.30.70.80.60.71.10.80.7-0.60.50.7-0.7
Intermittent access day 15 total infusions3.43.85.12.02.11.71.92.32.11.9-1.81.71.9-1.9
Intermittent access terminal intake (last 3 days)3.23.54.81.82.11.71.72.22.11.8-1.81.71.8-1.8
Intermittent access total infusions4.04.45.92.22.31.92.12.42.12.1-2.01.92.1-2.1
Intermittent access day 1 locomotion0.20.20.60.40.40.40.40.70.20.4-0.40.40.4-0.4
Intermittent access day 15 total locomotion3.03.25.22.21.90.91.82.31.81.7-1.61.71.8-1.7
Intermittent access total locomotion1.71.93.11.51.51.11.41.81.21.3-1.31.21.4-1.4
Intermittent access standard deviation1.11.22.51.61.10.21.01.61.50.8-0.70.71.0-0.9
Cocaine induced anxiety0.60.71.2-0.6-0.8-1.0-0.8-0.3-0.6-1.01.0-1.1-0.80.9
Post-drug Anxiety0.10.10.2-0.30.0-0.0-0.30.10.1-0.30.3-0.4-0.20.2
Baseline Anxiety0.00.00.10.10.10.30.1-0.10.10.1-0.20.10.1-0.2
Lifetime Intake3.94.45.32.12.21.92.22.32.12.1-2.01.82.2-2.2
Incentive Sensitization - Responses3.03.07.50.91.72.71.71.01.11.9-2.01.81.8-1.8
Incentive Sensitization - Breakpoint2.82.86.90.91.72.61.61.01.01.8-1.91.71.7-1.8
Progressive ratio test 1 active lever presses1.01.11.30.81.11.10.91.10.81.1-1.11.11.0-1.0
Progressive ratio test 1 breakpoint1.21.31.81.01.21.01.01.21.01.2-1.21.31.1-1.1
Progressive ratio test 1 inactive lever presses1.92.13.01.51.31.11.41.41.21.5-1.51.71.5-1.5
Progressive ratio test 2 active lever presses5.05.38.91.72.43.02.31.91.82.5-2.52.42.4-2.4
Progressive ratio test 2 breakpoint3.84.27.21.42.12.72.01.61.52.2-2.32.22.1-2.1
Progressive ratio test 2 inactive lever presses2.12.54.91.01.42.21.60.91.01.8-1.81.81.6-1.7
Total sessions with >9 infusions5.96.57.62.32.52.82.72.32.22.7-2.62.42.7-2.7
Short access day 1 total inactive lever presses0.30.30.40.50.60.60.50.50.60.6-0.60.70.5-0.6
Short access day 10 total inactive lever presses0.30.41.50.50.20.20.6-0.10.00.7-0.81.20.5-0.6
Short access day 1 total infusions5.76.06.62.52.62.32.52.52.42.5-2.42.22.6-2.5
Short access day 10 total infusions0.30.30.90.80.60.10.61.00.80.4-0.40.20.6-0.5
Short access total infusions2.42.63.21.81.71.31.71.81.71.6-1.51.31.7-1.7
Short access day 1 locomotion2.32.53.21.71.41.21.81.41.31.7-1.61.71.7-1.7
Short access day 10 total locomotion0.10.10.4-0.4-0.5-0.1-0.2-0.3-0.7-0.30.3-0.4-0.30.3
Short access total locomotion0.20.20.40.40.20.50.60.30.00.5-0.50.40.5-0.5
Compulsive drug intake1.51.52.5-1.4-1.4-0.6-1.1-1.6-1.4-1.11.1-1.1-1.11.1
One hour access (0.3 mA shock)1.72.03.01.21.11.71.71.00.91.5-1.51.31.6-1.6
One hour access (shock baseline)4.85.56.52.52.42.02.52.62.22.3-2.32.12.5-2.4
Number of responses in last shaping day1.41.53.21.81.2-0.11.11.81.60.9-0.81.01.0-1.0
Context. condit. distance diff. score0.20.20.70.40.80.50.20.70.80.3-0.3-0.00.4-0.3
Locomotion velocity, session 12.02.12.8-1.7-1.6-0.9-1.4-1.5-1.7-1.41.4-1.4-1.51.4
Locomotion distance, session 11.11.42.0-1.3-1.3-1.0-1.2-1.0-1.4-1.21.1-1.0-1.21.2
Locomotion velocity, session 20.20.20.4-0.3-0.2-0.7-0.7-0.2-0.2-0.40.4-0.3-0.60.6
Locomotion distance, session 20.00.00.1-0.00.2-0.1-0.20.10.00.1-0.10.3-0.10.1
Locomotion velocity, session 30.70.81.5-1.2-0.6-0.4-1.2-0.7-0.7-0.90.9-0.9-1.01.0
Locomotion distance, session 30.91.01.7-1.2-0.8-0.8-1.3-0.8-0.8-1.01.0-0.9-1.21.2
Stereotopy head waving bouts, day 31.01.21.61.11.21.01.01.21.31.0-1.00.91.1-1.0
Stereotopy head waving duration, day 30.10.10.1-0.3-0.4-0.3-0.3-0.4-0.3-0.30.3-0.3-0.30.3
Locomotion velocity, session 70.40.41.00.11.01.00.10.50.70.6-0.70.70.4-0.5
Locomotion distance, session 72.22.74.11.42.01.81.41.81.81.6-1.61.51.6-1.6
Stereotopy head waving bouts, day 72.73.13.7-1.9-1.8-1.5-1.9-1.7-1.7-1.71.7-1.5-1.91.8
Stereotopy head waving duration, day 74.25.16.0-2.4-2.3-2.0-2.4-2.1-2.2-2.32.2-2.0-2.42.4
Locomotion velocity, session 80.30.41.3-0.1-0.2-1.1-0.80.1-0.2-0.70.7-0.7-0.70.7
Locomotion distance, session 80.10.10.2-0.20.2-0.2-0.50.30.1-0.30.3-0.4-0.30.3
Degree of sensitization distance7.67.78.52.72.82.82.92.52.52.8-2.82.62.9-2.9
Degree of sensitization stereotypy4.34.75.1-2.2-2.2-2.0-2.2-2.0-2.1-2.22.2-2.2-2.32.3
Condit. Reinf. active minus inactive responses2.12.43.7-1.9-1.7-0.7-1.4-1.9-1.9-1.41.3-1.4-1.51.4
Condit. Reinf. active-inactive response ratio0.10.10.4-0.6-0.30.6-0.1-0.6-0.4-0.0-0.1-0.0-0.10.0
Condit. Reinf. active responses4.25.16.8-2.6-2.4-1.3-2.2-2.4-2.5-2.22.2-2.3-2.22.2
Condit. Reinf. inactive responses2.83.34.5-1.6-1.9-1.8-1.8-1.4-1.7-2.02.0-2.1-1.81.9
Incentive salience index mean4.35.27.3-2.7-2.5-1.3-2.2-2.5-2.6-2.22.1-2.2-2.32.2
Condit. Reinf. lever presses5.37.19.3-3.1-2.9-1.7-2.6-2.7-2.9-2.72.6-2.7-2.72.6
Time in familiar zone, hab. session 10.50.40.6-0.7-0.8-0.4-0.6-0.6-0.7-0.70.7-0.8-0.60.6
Time in novel zone, hab. session 10.90.91.31.11.00.40.80.81.10.9-0.91.20.9-0.9
Total zone transitions, hab. session 10.40.60.9-0.9-0.8-0.6-0.9-0.6-0.8-0.80.7-0.7-0.90.8
Total locomotion distance, hab. session 10.00.00.1-0.00.0-0.2-0.20.30.1-0.10.1-0.0-0.10.1
Locomotion velocity, hab. session 10.20.30.4-0.4-0.4-0.7-0.60.0-0.3-0.60.6-0.6-0.60.6
Time in familiar zone, hab. session 20.10.10.50.70.2-0.40.30.60.4-0.00.1-0.30.2-0.2
Time in novel zone, hab. session 20.10.10.2-0.40.00.4-0.2-0.4-0.10.1-0.20.3-0.10.0
Total zone transitions, hab. session 22.12.73.5-1.4-1.6-1.9-1.8-1.0-1.4-1.81.8-1.6-1.81.8
Total locomotion distance, hab. session 20.81.13.1-0.6-0.8-1.8-1.2-0.2-0.6-1.11.2-0.8-1.21.2
Locomotion velocity, hab. session 21.01.43.4-0.7-1.1-1.8-1.4-0.4-0.8-1.31.3-0.9-1.31.3
Novel to familiar place preference ratio1.81.92.61.31.61.51.31.31.51.4-1.41.31.3-1.4
Novelty place preference1.71.82.51.21.61.41.21.31.41.3-1.31.21.3-1.3
Time in novel zone, NPP test1.51.62.31.11.51.41.11.21.41.3-1.31.11.2-1.2
Total zone transitions, NPP test1.01.51.8-1.2-1.3-1.2-1.3-1.0-1.3-1.21.2-1.1-1.31.3
Total locomotion distance, NPP test0.20.20.80.40.30.30.40.30.30.6-0.60.90.5-0.5
Locomotion velocity, NPP test0.10.20.80.30.30.20.30.30.20.5-0.50.90.4-0.4
Pavlov. Cond. lever latency1.62.03.21.71.70.51.21.81.81.3-1.21.21.3-1.3
Pavlov. Cond. magazine entry latency0.20.30.6-0.7-0.80.0-0.3-0.7-0.8-0.50.5-0.6-0.40.4
Pavlov. Cond. change in total contacts1.01.12.0-1.0-1.4-0.7-0.7-1.4-1.4-0.90.9-0.8-0.90.9
Pavlov. Cond. index score2.53.24.8-2.1-2.1-1.0-1.6-2.2-2.2-1.71.6-1.5-1.71.7
Pavlov. Cond. latency score2.32.94.6-2.1-2.0-0.7-1.5-2.1-2.2-1.61.5-1.4-1.61.5
Pavlov. Cond. lever contacts2.42.84.2-2.0-2.0-0.7-1.5-2.0-2.1-1.61.5-1.5-1.61.6
Pavlov. Cond. magazine entry number1.01.32.11.31.40.50.91.41.41.0-1.01.01.0-1.0
Pavlov. Cond. intertrial magazine entries2.02.42.7-1.6-1.6-1.4-1.6-1.3-1.6-1.61.6-1.7-1.61.6
Pavlov. Cond. lever-magazine prob. diff.2.73.35.0-2.1-2.2-1.0-1.7-2.2-2.2-1.71.6-1.5-1.81.7
Pavlov. Cond. response bias3.13.85.0-2.2-2.2-1.1-1.8-2.1-2.2-1.91.9-1.9-1.91.9
Bone: apparent density0.30.50.70.60.80.50.50.70.80.7-0.70.80.6-0.6
Bone surface0.30.50.70.90.70.20.70.60.80.7-0.70.80.7-0.6
Bone volume0.20.40.70.80.70.10.50.60.80.7-0.60.90.6-0.6
Bone: connectivity density0.60.91.40.91.20.90.81.21.20.9-0.80.70.9-0.9
Bone: cortical apparent density0.71.02.0-1.4-1.1-0.2-0.9-1.3-1.2-0.80.8-0.8-0.90.9
Bone: cortical area0.00.00.00.00.10.00.1-0.10.00.1-0.20.20.1-0.1
Bone: cortical porosity2.12.24.6-0.8-1.2-2.1-1.6-0.3-1.0-1.71.8-1.7-1.61.6
Bone: cortical porosity2.22.34.4-0.9-1.3-2.1-1.6-0.4-1.1-1.71.8-1.8-1.61.7
Bone: cortical thickness0.20.30.4-0.7-0.6-0.4-0.6-0.6-0.7-0.50.5-0.5-0.50.5
Bone: cortical thickness0.91.01.4-1.1-0.9-0.8-1.2-1.0-1.1-1.01.0-0.9-1.11.1
Bone: cortical tissue density0.70.92.0-1.4-1.1-0.2-0.9-1.3-1.2-0.80.8-0.8-0.90.8
Bone: elastic displacement0.20.31.01.00.5-0.50.40.90.70.2-0.10.10.3-0.2
Bone: elastic work0.20.31.2-0.0-0.4-1.1-0.5-0.1-0.3-0.50.5-0.4-0.50.5
Bone: endosteal estimation0.51.11.41.11.20.80.91.11.21.0-1.01.01.0-1.0
Bone: endosteal perimeter0.91.82.61.51.51.01.31.51.61.3-1.21.11.3-1.3
Bone: final force0.50.81.2-0.9-0.8-1.0-1.1-0.4-0.7-1.01.0-0.9-1.01.0
Bone: final moment0.81.31.8-1.1-1.0-1.3-1.3-0.6-0.9-1.21.3-1.2-1.21.3
Bone: marrow area0.51.21.61.11.20.81.01.21.31.1-1.01.11.1-1.1
Bone: maximum diameter0.81.42.01.41.30.61.11.11.41.2-1.11.21.2-1.1
Bone: maximum force0.40.71.6-0.5-0.6-1.3-1.0-0.1-0.4-0.91.0-0.8-0.90.9
Bone: maximum moment0.71.22.1-0.8-0.9-1.5-1.2-0.4-0.8-1.21.2-1.1-1.21.2
Bone: minimum diameter0.20.40.60.80.60.20.60.50.70.7-0.60.80.6-0.6
Bone: periosteal estimation0.61.21.41.11.20.91.01.01.11.1-1.11.21.1-1.1
Bone: periosteal perimeter0.40.70.90.90.90.70.80.70.90.9-0.90.90.9-0.9
Bone: post-yield work0.10.10.40.30.1-0.7-0.10.40.3-0.10.20.0-0.10.1
Bone: stiffness0.00.00.1-0.10.1-0.2-0.20.00.10.0-0.10.3-0.10.1
Bone: tissue strength0.30.20.30.40.50.50.50.50.50.5-0.50.40.5-0.5
Bone: trabecular number0.40.61.10.71.00.80.61.01.00.7-0.60.50.7-0.7
Bone: trabecular spacing0.30.30.5-0.5-0.5-0.7-0.6-0.3-0.5-0.70.7-0.7-0.60.6
Bone: trabecular thickness0.40.50.8-0.7-0.7-0.9-0.8-0.8-0.7-0.60.6-0.3-0.70.7
Bone: trabecular tissue density0.40.61.2-0.9-0.9-0.6-0.7-1.1-0.9-0.60.6-0.4-0.70.7
Breakpoint value in progressive ratio session0.00.00.10.20.0-0.3-0.00.20.10.0-0.00.10.0-0.0
Distance traveled before self-admin0.10.10.5-0.2-0.2-0.3-0.30.3-0.0-0.40.5-0.7-0.30.3
Distance traveled after self-admin0.20.31.30.40.60.30.31.10.60.2-0.1-0.30.4-0.3
Delta time in closed arm before/after self-admin0.20.20.70.50.6-0.00.20.50.80.3-0.30.30.3-0.3
Delta time in open arm before/after self-admin4.64.46.51.72.02.62.21.01.42.4-2.42.42.3-2.3
Diff in mean of infusions in LGA sessions0.20.20.50.70.5-0.50.20.60.60.3-0.30.50.3-0.3
Extinction: sum of active levers before priming0.10.10.40.30.30.40.30.60.20.3-0.30.20.3-0.3
Active lever presses in extinction session 60.10.10.80.20.3-0.1-0.10.90.3-0.10.1-0.2-0.00.0
Delta distance traveled before/after self-admin1.01.11.60.91.11.31.10.60.81.2-1.21.01.1-1.2
Delta ambulatory time before/after self-admin0.70.70.90.80.90.90.90.80.70.9-0.90.80.9-0.9
Time in closed arm before self-admin1.72.02.6-1.4-1.3-1.5-1.6-0.9-1.3-1.51.5-1.4-1.61.6
Time in closed arm after self-admin2.93.14.1-1.6-1.7-2.0-1.9-1.3-1.3-1.91.9-1.7-1.91.9
Time in open arm before self-admin0.91.01.8-0.6-0.8-1.3-1.0-0.2-0.3-1.21.2-1.4-1.01.1
Time in open arm after self-admin2.93.24.81.31.82.21.81.01.42.0-2.02.01.9-1.9
Sum of active levers in priming session hrs 5-60.00.00.1-0.2-0.00.4-0.10.0-0.20.0-0.00.0-0.00.0
Time to tail flick, vehicle, before self-admin0.40.41.2-0.6-0.3-0.3-0.70.3-0.1-0.80.8-1.1-0.60.7
Time to tail flick, vehicle, after self-admin0.10.10.90.30.0-1.0-0.3-0.10.4-0.20.2-0.1-0.20.3
Time to tail flick, test, before self-admin1.11.11.3-1.1-1.0-0.9-1.1-0.9-0.8-1.11.1-1.1-1.11.1
Time to tail flick, test, after self-admin0.90.91.41.01.01.21.10.91.00.9-0.80.61.0-1.0
Delta time to tail flick, vehicle, before/after SA0.70.71.91.00.7-0.00.70.00.71.0-1.01.40.8-0.8
Delta time to tail flick, test, before/after SA1.21.02.10.91.11.41.11.10.90.9-0.90.61.0-1.0
Ambulatory time before self-admin1.11.11.9-1.0-1.0-1.0-1.1-0.4-0.7-1.21.2-1.4-1.11.1
Ambulatory time after self-admin0.50.51.3-0.4-0.4-0.8-0.70.4-0.2-0.80.9-1.2-0.70.7
Total heroin consumption0.50.61.2-1.0-1.0-0.1-0.6-1.0-1.1-0.60.6-0.7-0.70.6
Area under the delay curve3.53.76.1-1.4-2.0-2.5-1.9-1.3-1.7-2.12.1-1.9-2.02.0
Delay disc. indifference point, 0s delay0.10.10.30.0-0.1-0.6-0.30.00.1-0.30.4-0.3-0.30.3
Delay disc. indifference point, 16s delay1.11.13.3-0.3-1.1-1.8-0.9-0.3-0.7-1.21.3-1.0-1.01.1
Delay disc. indifference point, 2s delay2.02.22.8-1.2-1.5-1.7-1.5-1.0-1.3-1.61.7-1.6-1.61.6
Delay disc. indifference point, 24s delay0.70.71.2-0.5-1.0-1.1-0.7-0.6-1.0-0.80.8-0.6-0.80.8
Delay disc. indifference point, 4s delay4.64.95.7-2.0-2.2-2.3-2.3-1.7-2.0-2.42.4-2.4-2.32.3
Delay disc. indifference point, 8s delay2.22.34.2-1.1-1.7-2.1-1.5-1.2-1.4-1.61.6-1.3-1.51.6
Delay discount exponential model param4.64.96.81.82.32.62.21.62.02.3-2.42.22.3-2.3
Delay discount hyperbolic model param4.95.27.21.82.42.72.31.72.12.4-2.42.32.4-2.4
Fecal boli incidents, locomotor time 11.92.13.9-1.6-1.7-1.2-1.3-2.0-1.7-1.21.1-0.8-1.41.3
Change in fecal boli incidents, locomotor task2.01.93.11.51.81.01.11.71.71.2-1.21.21.2-1.2
Time >=10cm from walls, locomotor time 10.20.20.5-0.5-0.2-0.3-0.6-0.0-0.0-0.60.6-0.7-0.50.5
Bouts of movement, locomotor time 10.20.20.6-0.5-0.5-0.5-0.6-0.8-0.4-0.30.3-0.1-0.50.5
Total resting periods, locomotor time 10.10.20.6-0.4-0.4-0.4-0.4-0.8-0.3-0.20.10.1-0.40.3
Rest time, locomotor task time 11.82.05.1-1.8-1.6-0.7-1.3-2.3-1.9-1.00.8-0.4-1.31.2
Distance moved, locomotor task time 10.90.92.71.31.10.50.91.61.30.6-0.50.10.9-0.8
Vertical activity count, locomotor time 10.91.03.21.70.9-0.70.71.81.30.3-0.1-0.00.7-0.5
Time >=10cm from walls, locomotor time 20.10.20.90.20.4-0.1-0.21.00.4-0.20.3-0.4-0.10.2
Bouts of movement, locomotor time 20.00.00.1-0.1-0.2-0.2-0.1-0.3-0.30.0-0.10.3-0.10.1
Total resting periods, locomotor time 20.10.10.6-0.4-0.5-0.3-0.3-0.8-0.6-0.10.00.2-0.30.2
Rest time, locomotor task time 21.51.84.9-1.6-1.6-0.8-1.2-2.2-1.6-0.90.8-0.3-1.31.2
Distance moved, locomotor task time 20.20.21.10.50.1-0.40.11.10.3-0.30.4-0.70.10.0
Vertical activity count, locomotor time 20.40.41.40.80.1-0.90.21.20.4-0.50.7-1.00.00.1
Weight adjusted by age1.51.72.7-1.6-1.4-0.7-1.4-1.2-1.5-1.31.2-1.2-1.41.3
Seeking ratio, delayed vs. immediate footshock0.60.71.51.11.00.60.91.21.10.6-0.50.10.9-0.8
Locomotion in novel chamber1.31.62.0-1.1-1.2-1.4-1.3-1.1-1.1-1.31.3-1.2-1.31.3
Locomotion in novel chamber post-restriction0.10.20.60.30.5-0.3-0.30.80.5-0.20.2-0.3-0.20.2
Progressive ratio0.10.20.80.1-0.3-0.9-0.3-0.3-0.1-0.30.4-0.2-0.30.3
Food seeking constrained by brief footshock0.40.50.90.80.40.40.90.20.40.8-0.80.90.8-0.8
Seeking ratio, punishment vs. effort0.00.00.1-0.1-0.10.30.10.1-0.20.0-0.10.00.1-0.1
Run reversals in cocaine runway, females0.40.40.90.40.81.00.50.70.90.4-0.3-0.10.6-0.5
Run reversals in cocaine runway, males1.31.21.5-1.1-1.2-1.0-1.0-1.0-1.0-1.21.2-1.2-1.11.1
Latency to leave start box in cocaine runway0.80.91.20.81.01.11.00.40.81.0-1.00.91.0-1.0
Latency to leave start box in cocaine runway, F1.51.72.31.11.21.51.40.60.91.4-1.51.41.4-1.4
Latency to leave start box in cocaine runway, M0.10.10.8-0.4-0.20.2-0.1-0.9-0.10.0-0.10.1-0.10.1
Cd content in liver1.11.21.81.10.90.91.20.41.01.2-1.31.41.2-1.2
Co content in liver0.20.20.9-0.1-0.4-0.9-0.5-0.3-0.3-0.50.5-0.3-0.50.5
Cu content in liver0.60.81.5-1.2-0.8-0.4-1.0-1.1-1.0-0.70.6-0.4-0.90.9
Fe content in liver0.30.41.10.20.61.10.40.40.50.6-0.60.60.5-0.6
K content in liver0.30.31.10.40.90.40.11.11.00.3-0.20.00.2-0.2
Mg content in liver1.41.52.81.21.51.01.01.61.71.1-1.00.81.1-1.1
Mn content in liver0.70.82.10.91.10.80.81.41.20.7-0.60.40.8-0.8
Na content in liver3.33.54.8-2.2-1.6-1.3-2.2-1.2-1.6-2.02.0-2.1-2.02.0
Rb content in liver4.15.17.32.62.51.52.22.62.72.1-2.01.92.2-2.2
Se content in liver2.63.14.52.11.91.11.81.82.01.7-1.61.61.8-1.8
Sr content in liver0.70.72.00.20.61.40.8-0.20.20.9-1.01.00.8-0.8
Zn content in liver1.01.12.7-0.6-1.1-1.6-1.1-0.5-0.9-1.11.1-0.9-1.11.1