Caprin1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009152 0.02 0.02 3.8e-03 0.02 0.02 0 0.01 2.8e-03 4.3e-03 1.3e-01 6.7e-03
2 BLA gene expression ENSRNOG00000009152 0.28 0.17 8.5e-09 0.16 0.14 0.14 0.15 9.6e-09 1.0e-07 1.1e-07 1.6e-08
3 Brain gene expression ENSRNOG00000009152 0.22 0.15 6.4e-15 0.18 0.17 0.18 0.18 1.1e-16 7.6e-16 2.0e-16 1.6e-16
4 Brain mRNA stability ENSRNOG00000009152 0.1 0.07 1.0e-08 0.09 0.09 0.09 0.09 2.4e-08 2.5e-08 2.4e-08 2.2e-08
5 IL gene expression ENSRNOG00000009152 0.17 0.12 1.9e-04 0.12 0.13 0.13 0.15 9.0e-04 5.5e-04 4.6e-04 2.2e-04
6 Liver gene expression ENSRNOG00000009152 0.25 0.13 0.0e+00 0.23 0.25 0.25 0.25 1.2e-25 1.1e-27 1.0e-27 2.0e-27
7 NAcc gene expression ENSRNOG00000009152 0.14 0.09 1.4e-08 0.11 0.1 0.1 0.11 1.4e-08 3.3e-08 3.1e-08 2.5e-08
8 OFC gene expression ENSRNOG00000009152 0.12 0.1 4.9e-03 0.06 0.08 0.07 0.07 1.4e-02 7.3e-03 7.7e-03 1.1e-02
9 PL gene expression ENSRNOG00000009152 0.27 0.17 2.3e-13 0.17 0.15 0.16 0.16 1.1e-12 9.7e-12 6.8e-12 2.0e-12
10 PL mRNA stability ENSRNOG00000009152 0.05 0.05 1.6e-03 0.03 0.03 0.02 0.03 1.5e-03 2.3e-03 1.6e-02 2.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.10.20.60.10.50.30.50.50.30.60.40.50.8
BMI without tail0.40.81.80.90.90.80.90.90.80.90.90.71.3
Body weight0.62.64.42.01.51.31.51.51.61.41.71.52.1
Epididymis fat weight0.81.92.21.11.41.41.51.41.41.51.41.51.2
Glucose2.23.44.22.11.71.81.81.92.01.72.01.71.9
Heart weight0.20.20.9-0.6-0.4-0.3-0.4-0.3-0.4-0.3-0.3-0.5-1.0
Left kidney weight0.61.63.61.91.01.01.01.31.50.81.41.11.4
Right kidney weight0.31.01.91.40.90.80.81.11.20.71.10.81.0
Tail length0.61.85.22.31.01.01.11.21.41.01.40.91.7
Length with tail0.72.56.32.51.31.31.31.41.61.11.61.31.9
Length without tail0.30.71.31.10.80.80.70.70.90.70.80.90.8
Liver weight, left0.50.71.91.40.50.50.50.91.00.50.90.41.2
Liver weight, right1.62.64.22.01.41.41.41.71.91.41.81.41.7
Parametrial fat weight0.71.42.71.01.21.11.21.11.01.31.11.11.6
Retroperitoneal fat weight8.929.332.44.55.75.65.55.65.75.45.45.65.1
Intraocular pressure0.10.10.4-0.60.10.20.1-0.0-0.30.1-0.1-0.1-0.5
Extensor digitorum longus weight0.21.01.3-0.5-1.1-1.1-1.1-1.1-1.0-1.1-1.0-1.1-0.7
Soleus weight1.85.37.0-2.6-2.3-2.3-2.3-2.3-2.1-2.2-2.3-2.3-2.3
Tibialis anterior weight2.58.89.9-2.6-3.1-3.1-3.1-3.0-2.9-3.1-2.9-3.1-2.5
Tibia length0.10.30.60.5-0.6-0.6-0.6-0.4-0.2-0.8-0.1-0.60.1
Number of licking bursts0.30.30.50.20.70.70.70.60.40.70.50.70.4
Food consumed during 24 hour testing period7.48.99.73.12.92.92.93.03.02.93.12.93.0
Times rat made contact with spout0.10.10.20.30.40.40.40.40.40.40.40.40.2
Mean time between licks in bursts1.01.31.6-1.3-1.1-1.1-1.1-1.2-1.2-1.1-1.3-1.1-1.2
Mean num. licks in bursts0.00.00.10.1-0.2-0.2-0.2-0.10.0-0.2-0.0-0.3-0.1
Std. dev. time between licks in bursts0.20.20.4-0.4-0.5-0.5-0.5-0.4-0.3-0.5-0.4-0.5-0.6
Water consumed over 24 hours0.20.30.40.60.50.50.50.60.60.50.60.50.4
Indifference point 0 sec0.50.82.2-1.5-0.6-0.5-0.6-0.9-1.0-0.5-1.1-0.5-1.2
Indifference point AUC1.41.62.3-0.6-1.4-1.5-1.4-1.3-1.3-1.4-1.2-1.5-0.6
Indifference point function ln k1.01.41.81.01.31.31.21.21.31.21.11.40.7
Indifference point function log k1.01.41.81.01.31.31.21.21.31.21.11.40.7
Delay discounting total patch changes 0 sec0.40.72.1-1.4-0.4-0.4-0.4-0.8-0.9-0.4-1.0-0.4-1.1
Delay discounting total patch changes 12 sec0.00.00.1-0.10.20.10.20.1-0.10.10.10.00.3
Delay discounting total patch changes 18 sec0.50.71.1-0.6-0.7-0.9-0.9-0.9-1.0-0.8-1.0-0.9-0.4
Delay discounting total patch changes 24 sec1.31.62.7-1.6-1.2-1.2-1.1-1.3-1.3-1.2-1.4-1.1-1.0
Delay discounting total patch changes 6 sec0.40.61.0-1.0-0.7-0.8-0.7-0.8-0.9-0.7-1.0-0.5-0.7
Delay discounting time to switch 0 sec0.00.00.1-0.3-0.3-0.3-0.2-0.2-0.1-0.1-0.2-0.1-0.2
Delay discounting water rate 0 sec0.00.00.0-0.10.20.20.20.1-0.00.1-0.1-0.00.2
Delay discounting water rate 12 sec0.00.00.1-0.0-0.2-0.3-0.3-0.1-0.0-0.3-0.1-0.30.2
Delay discounting water rate 18 sec0.91.21.51.11.11.11.11.11.10.91.11.21.2
Delay discounting water rate 24 sec0.10.10.30.50.1-0.10.00.30.5-0.10.3-0.20.3
Delay discounting water rate 6 sec0.00.00.1-0.00.30.10.10.30.30.10.1-0.0-0.0
Locomotor activity0.10.10.2-0.30.30.40.30.30.10.50.20.30.1
Locomotor testing distance1.32.12.70.81.41.61.51.51.51.71.41.31.5
Locomotor testing rearing0.20.30.40.10.60.60.60.60.70.60.60.30.6
Light reinforcement 10.10.20.40.60.20.20.30.40.60.10.50.60.6
Light reinforcement 20.00.00.20.40.0-0.00.00.10.3-0.10.30.00.2
Reaction time number correct0.10.10.30.50.20.10.30.30.20.20.20.20.6
Reaction time mean minus median0.10.10.10.40.30.30.20.30.30.30.40.30.4
Reaction time mean minus median AUC0.10.10.20.50.30.30.30.30.40.30.40.20.4
Reaction time num false alarms1.41.92.4-1.1-1.2-1.2-1.3-1.4-1.5-1.4-1.4-1.5-1.4
Reaction time num false alarms AUC1.82.53.2-1.3-1.5-1.5-1.6-1.7-1.7-1.6-1.6-1.8-1.5
Reaction time trials correct on left0.10.10.30.50.20.10.30.30.20.20.20.20.6
Reaction time trials on left0.00.00.20.40.10.00.20.20.10.10.10.00.5
Reaction time mean0.20.30.50.70.40.40.40.50.70.60.60.40.7
Reaction time mean AUC0.40.50.90.80.60.60.60.71.00.80.80.60.8
Median of all reaction times0.50.71.00.90.60.60.70.81.00.90.90.71.0
Reaction time omissions1.31.82.5-1.6-1.4-1.3-1.4-1.2-1.0-1.4-1.3-1.3-1.4
Reaction time false alarm rate2.73.84.2-1.9-1.8-1.8-1.9-2.0-2.1-1.9-2.0-2.1-2.0
Reaction time premature initiation rate0.10.10.30.1-0.5-0.4-0.3-0.4-0.4-0.3-0.2-0.6-0.5
Reaction time premature initiations0.00.10.20.3-0.3-0.3-0.1-0.2-0.2-0.2-0.1-0.4-0.1
Std. dev. reaction times0.00.00.10.20.0-0.0-0.10.10.20.10.2-0.00.1
Reaction time trials completed0.00.00.20.40.10.00.20.20.10.10.10.00.5
Reaction time trials AUC0.10.20.50.60.30.20.40.40.30.30.40.30.7
Social response proportion3.84.15.4-1.4-2.3-2.3-2.2-2.0-1.7-2.2-2.0-2.2-1.8
Social responses0.10.10.30.50.20.20.20.30.40.20.40.00.1
Social time2.22.83.7-1.6-1.9-1.7-1.6-1.8-1.8-1.4-1.8-1.8-1.5
Conditioned locomotion3.74.45.7-2.1-2.0-2.0-2.0-2.2-2.4-2.0-2.3-2.0-1.9
Cocaine response after cond. corrected2.73.03.4-1.5-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.3
Cocaine response after cond. not corrected0.40.50.6-0.5-0.7-0.7-0.7-0.8-0.8-0.8-0.7-0.8-0.1
Cocaine response before conditioning6.68.19.22.62.82.82.92.92.92.82.82.93.0
Saline control response0.71.01.11.01.11.11.10.90.71.00.91.01.1
Condit. Reinf. active minus inactive responses1.82.32.91.41.41.41.51.51.61.51.51.41.7
Condit. Reinf. active-inactive response ratio5.05.26.62.42.22.22.22.32.32.22.32.12.6
Condit. Reinf. active responses1.01.42.01.01.21.21.21.21.21.21.21.21.4
Condit. Reinf. inactive responses0.10.10.5-0.7-0.1-0.1-0.1-0.3-0.3-0.1-0.3-0.1-0.3
Condit. Reinf. lever presses0.81.11.30.71.01.01.11.11.11.11.11.01.1
Condit. Reinf. lever reinforcers received1.01.31.60.81.21.21.21.21.21.21.21.21.3
Pavlov. Cond. lever latency2.43.33.8-1.4-1.9-1.9-1.9-1.9-1.9-1.9-1.8-1.8-1.6
Pavlov. Cond. magazine entry latency0.80.91.20.51.01.01.01.01.01.10.91.00.6
Pavlov. Cond. change in total contacts1.11.62.00.91.31.31.41.31.21.41.31.21.2
Pavlov. Cond. index score2.02.63.21.11.71.71.71.71.71.81.61.71.3
Pavlov. Cond. latency score2.43.13.81.21.91.91.91.81.81.91.71.81.5
Pavlov. Cond. lever contacts2.83.84.71.42.12.12.12.02.02.21.92.01.7
Pavlov. Cond. magazine entry number0.40.50.7-0.3-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.7-0.3
Pavlov. Cond. intertrial magazine entries0.00.00.10.1-0.3-0.3-0.2-0.2-0.1-0.3-0.1-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.1.82.32.81.01.61.61.61.61.61.71.51.51.3
Pavlov. Cond. response bias2.12.83.41.31.71.71.81.81.81.81.71.71.3
Conditioned reinforcement - actives4.24.27.52.71.71.72.01.91.82.12.11.62.5
Conditioned reinforcement - inactives9.210.411.33.13.23.23.33.33.23.43.23.23.2
Conditioned locomotion1.61.92.41.01.41.51.51.41.31.51.31.41.5
Intermittent access intake day 1-15 change0.20.20.3-0.30.40.40.50.50.40.60.30.50.5
Intermittent access intake escalation0.50.50.70.10.70.70.70.80.60.90.60.80.7
Intermittent access intake escalation 22.82.83.31.31.71.71.71.81.61.81.71.81.7
Intermitt. access day 1 inactive lever presses0.10.10.70.6-0.1-0.1-0.20.30.8-0.20.4-0.1-0.1
Intermitt. access day 15 inactive lever presses2.93.24.21.81.71.71.71.82.01.81.81.71.6
Intermitt. access escalation Index0.60.61.21.10.60.70.80.50.40.90.70.51.1
Intermittent access day 1 total infusions3.23.74.82.21.92.02.01.81.72.01.81.82.1
Intermittent access day 15 total infusions4.65.26.52.02.32.32.42.21.92.52.22.22.5
Intermittent access terminal intake (last 3 days)6.67.28.62.62.72.72.82.62.32.92.62.62.9
Intermittent access total infusions6.67.38.72.72.72.82.82.62.32.92.62.52.9
Intermittent access day 1 locomotion1.21.21.51.11.21.21.21.00.91.21.00.91.2
Intermittent access day 15 total locomotion1.01.11.80.21.31.31.31.00.61.10.81.41.0
Intermittent access total locomotion1.71.92.60.81.61.61.61.31.11.61.21.41.3
Intermittent access standard deviation5.55.96.72.32.52.52.52.52.32.62.42.42.4
Cocaine induced anxiety0.40.51.00.60.60.60.60.81.00.60.80.60.5
Post-drug Anxiety0.00.00.0-0.0-0.00.10.1-0.00.20.10.10.20.0
Baseline Anxiety3.03.24.5-1.7-1.7-1.7-1.7-2.0-2.1-1.7-1.9-1.5-1.7
Lifetime Intake7.17.99.12.82.82.92.92.72.53.02.72.63.0
Incentive Sensitization - Responses1.11.11.40.91.01.01.11.21.01.21.10.91.2
Incentive Sensitization - Breakpoint0.90.91.10.80.90.91.01.10.91.11.00.81.0
Progressive ratio test 1 active lever presses3.73.84.42.11.92.02.01.91.82.02.01.82.0
Progressive ratio test 1 breakpoint3.53.64.32.11.91.91.91.91.81.91.91.72.0
Progressive ratio test 1 inactive lever presses1.92.12.41.51.41.41.41.51.61.41.51.31.4
Progressive ratio test 2 active lever presses2.62.83.21.71.61.61.71.71.51.81.71.51.8
Progressive ratio test 2 breakpoint3.23.64.21.91.91.92.01.91.72.02.01.82.0
Progressive ratio test 2 inactive lever presses3.74.34.92.02.02.02.02.22.12.22.12.02.0
Total sessions with >9 infusions2.52.73.51.91.61.61.71.61.61.81.61.31.8
Short access day 1 total inactive lever presses0.91.01.30.91.11.11.11.01.01.20.90.90.9
Short access day 10 total inactive lever presses0.20.20.90.40.30.30.20.60.90.20.60.4-0.0
Short access day 1 total infusions9.810.412.23.53.23.33.33.23.03.33.22.83.4
Short access day 10 total infusions3.53.95.11.72.12.22.22.01.62.31.81.92.1
Short access total infusions5.86.47.42.52.52.62.72.52.32.72.42.32.7
Short access day 1 locomotion3.84.05.11.82.22.22.21.81.52.21.81.92.0
Short access day 10 total locomotion2.52.73.61.01.81.91.81.71.51.81.61.61.4
Short access total locomotion3.03.14.11.21.92.02.01.71.52.01.61.71.7
Compulsive drug intake2.02.02.3-1.4-1.4-1.5-1.4-1.5-1.2-1.3-1.3-1.4-1.5
One hour access (0.3 mA shock)2.63.03.71.31.71.71.81.71.71.91.71.81.8
One hour access (shock baseline)6.06.97.72.22.72.82.82.72.32.82.62.72.7
Number of responses in last shaping day2.02.12.81.71.31.31.51.51.41.51.51.11.6
Context. condit. distance diff. score3.44.15.21.92.02.02.02.22.32.02.22.01.8
Locomotion velocity, session 10.10.10.3-0.2-0.2-0.2-0.2-0.2-0.3-0.3-0.3-0.2-0.6
Locomotion distance, session 10.00.00.1-0.20.0-0.0-0.0-0.2-0.2-0.1-0.20.1-0.3
Locomotion velocity, session 20.00.00.10.20.00.10.1-0.1-0.10.0-0.00.00.3
Locomotion distance, session 20.20.20.30.50.40.50.50.40.40.50.40.50.5
Locomotion velocity, session 30.00.00.1-0.20.20.30.2-0.0-0.30.2-0.10.20.0
Locomotion distance, session 30.10.10.20.30.40.50.40.20.10.40.20.40.1
Stereotopy head waving bouts, day 30.10.10.3-0.5-0.2-0.2-0.2-0.4-0.6-0.3-0.5-0.3-0.3
Stereotopy head waving duration, day 30.40.50.90.70.70.70.70.70.70.70.60.70.9
Locomotion velocity, session 70.00.00.10.2-0.0-0.1-0.10.20.3-0.10.2-0.00.1
Locomotion distance, session 70.40.50.7-0.3-0.8-0.9-0.8-0.6-0.5-0.8-0.6-0.8-0.7
Stereotopy head waving bouts, day 70.00.00.1-0.10.30.30.30.1-0.10.3-0.00.20.3
Stereotopy head waving duration, day 70.00.00.20.10.20.20.20.1-0.10.20.00.10.5
Locomotion velocity, session 80.40.50.80.90.70.60.60.80.90.60.80.70.4
Locomotion distance, session 83.14.65.12.12.12.12.12.22.32.12.22.22.1
Degree of sensitization distance0.20.20.5-0.1-0.6-0.7-0.7-0.30.0-0.7-0.2-0.6-0.3
Degree of sensitization stereotypy0.00.00.1-0.30.10.10.1-0.1-0.40.1-0.2-0.00.3
Condit. Reinf. active minus inactive responses1.51.72.00.71.41.41.41.31.31.41.31.31.1
Condit. Reinf. active-inactive response ratio3.23.54.01.31.92.02.02.02.02.01.91.91.6
Condit. Reinf. active responses0.50.60.80.30.90.90.80.80.70.90.70.80.7
Condit. Reinf. inactive responses0.50.60.7-0.6-0.7-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.4
Incentive salience index mean1.41.72.10.91.41.41.41.31.31.51.31.41.2
Condit. Reinf. lever presses1.21.51.91.11.21.31.31.21.21.41.31.31.2
Time in familiar zone, hab. session 10.70.70.8-0.4-0.9-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.9
Time in novel zone, hab. session 11.31.31.70.61.31.21.21.31.11.11.11.21.1
Total zone transitions, hab. session 11.72.53.11.01.71.71.81.61.41.71.51.81.3
Total locomotion distance, hab. session 10.40.61.1-0.11.01.01.00.70.41.00.41.10.3
Locomotion velocity, hab. session 10.20.30.6-0.30.70.70.70.40.10.70.20.80.1
Time in familiar zone, hab. session 20.10.10.4-0.4-0.1-0.1-0.1-0.2-0.3-0.1-0.3-0.1-0.6
Time in novel zone, hab. session 20.30.30.70.80.30.30.30.50.60.30.60.30.9
Total zone transitions, hab. session 21.51.92.41.41.31.41.41.31.31.41.41.41.5
Total locomotion distance, hab. session 20.00.10.2-0.4-0.1-0.1-0.1-0.3-0.3-0.1-0.3-0.1-0.3
Locomotion velocity, hab. session 20.10.10.2-0.5-0.2-0.2-0.2-0.3-0.4-0.1-0.4-0.2-0.4
Novel to familiar place preference ratio0.60.70.90.40.80.90.90.80.90.90.80.90.5
Novelty place preference0.60.70.90.50.80.90.90.91.00.90.90.90.5
Time in novel zone, NPP test0.50.50.80.40.70.80.80.80.90.80.80.70.4
Total zone transitions, NPP test0.50.71.2-0.9-0.8-0.8-0.7-0.9-1.1-0.7-1.0-0.6-0.9
Total locomotion distance, NPP test0.71.01.6-1.3-0.8-0.8-0.8-1.0-1.2-0.8-1.1-0.7-1.1
Locomotion velocity, NPP test0.60.91.4-1.2-0.7-0.8-0.7-1.0-1.2-0.7-1.1-0.7-1.0
Pavlov. Cond. lever latency0.50.60.8-0.9-0.8-0.8-0.8-0.7-0.7-0.9-0.8-0.9-0.7
Pavlov. Cond. magazine entry latency0.91.22.11.40.90.90.91.11.21.01.21.01.0
Pavlov. Cond. change in total contacts0.20.20.5-0.2-0.5-0.5-0.5-0.5-0.4-0.4-0.4-0.5-0.7
Pavlov. Cond. index score0.20.30.50.70.40.40.50.50.60.50.60.50.4
Pavlov. Cond. latency score0.20.30.50.70.40.50.50.50.60.50.60.50.4
Pavlov. Cond. lever contacts0.40.50.91.00.60.60.60.60.70.70.80.80.6
Pavlov. Cond. magazine entry number0.91.11.7-1.3-0.9-0.9-0.9-1.1-1.2-1.0-1.2-0.9-1.0
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.50.10.0-0.0-0.1-0.1-0.1-0.2-0.1-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.40.60.40.40.40.40.50.50.50.50.3
Pavlov. Cond. response bias0.91.12.11.40.90.90.91.01.21.01.21.01.1
Bone: apparent density0.61.01.30.61.11.11.11.00.81.10.91.11.0
Bone surface0.61.01.50.71.11.11.10.90.81.00.91.11.2
Bone volume1.32.22.71.11.61.61.61.51.31.61.41.61.4
Bone: connectivity density0.61.01.50.61.01.01.00.90.81.10.91.01.2
Bone: cortical apparent density0.10.10.3-0.0-0.6-0.6-0.5-0.30.0-0.3-0.2-0.5-0.1
Bone: cortical area0.30.51.71.30.40.40.40.60.70.50.80.30.9
Bone: cortical porosity0.50.50.9-0.8-0.7-0.6-0.6-0.7-0.8-0.6-0.7-0.7-0.9
Bone: cortical porosity0.20.20.3-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.5-0.6
Bone: cortical thickness0.10.10.80.9-0.1-0.10.00.10.20.20.3-0.10.6
Bone: cortical thickness2.93.44.1-1.6-2.0-1.9-1.9-1.9-1.8-1.8-1.8-2.0-1.5
Bone: cortical tissue density0.10.10.20.0-0.5-0.5-0.4-0.20.1-0.2-0.1-0.40.0
Bone: elastic displacement1.31.51.9-0.9-1.3-1.4-1.4-1.2-1.2-1.4-1.1-1.3-1.0
Bone: elastic work1.21.51.9-1.0-1.3-1.3-1.3-1.2-1.2-1.4-1.1-1.4-1.1
Bone: endosteal estimation0.20.40.7-0.8-0.5-0.5-0.6-0.6-0.6-0.8-0.6-0.5-0.8
Bone: endosteal perimeter0.30.50.70.40.80.90.80.80.70.70.70.80.4
Bone: final force0.00.10.30.6-0.1-0.1-0.10.20.3-0.20.2-0.00.1
Bone: final moment0.10.10.30.3-0.4-0.4-0.5-0.20.0-0.6-0.1-0.4-0.2
Bone: marrow area0.20.40.7-0.8-0.5-0.5-0.6-0.6-0.6-0.9-0.6-0.5-0.8
Bone: maximum diameter0.30.50.80.90.60.60.60.70.80.60.80.60.5
Bone: maximum force0.00.10.20.50.20.20.20.20.20.10.30.20.3
Bone: maximum moment0.00.10.20.1-0.3-0.3-0.3-0.2-0.2-0.4-0.2-0.3-0.1
Bone: minimum diameter0.81.62.71.61.11.11.11.21.31.11.31.11.4
Bone: periosteal estimation0.00.00.10.1-0.2-0.1-0.2-0.1-0.0-0.30.0-0.20.0
Bone: periosteal perimeter1.01.72.41.51.21.31.31.31.21.31.41.21.3
Bone: post-yield work0.00.00.1-0.40.00.10.1-0.1-0.10.1-0.10.1-0.3
Bone: stiffness0.40.71.21.10.80.80.80.90.90.70.90.70.6
Bone: tissue strength0.20.20.6-0.7-0.2-0.2-0.3-0.3-0.5-0.5-0.4-0.2-0.8
Bone: trabecular number0.60.91.20.61.01.01.00.90.81.10.90.91.0
Bone: trabecular spacing0.10.10.20.40.30.40.40.40.30.20.40.30.3
Bone: trabecular thickness0.20.20.30.50.50.50.50.50.50.50.50.40.5
Bone: trabecular tissue density1.52.02.8-1.3-1.4-1.4-1.4-1.4-1.2-1.5-1.4-1.5-1.7
Breakpoint value in progressive ratio session1.11.21.8-0.3-1.3-1.4-1.3-1.1-0.9-1.3-0.9-1.3-0.9
Distance traveled before self-admin0.50.50.80.90.70.70.70.70.70.40.80.70.7
Distance traveled after self-admin0.80.93.31.80.70.70.70.80.90.41.10.81.0
Delta time in closed arm before/after self-admin0.10.10.30.0-0.3-0.3-0.4-0.2-0.2-0.3-0.2-0.1-0.5
Delta time in open arm before/after self-admin0.40.31.7-1.3-0.2-0.1-0.1-0.5-0.9-0.2-0.6-0.1-0.5
Diff in mean of infusions in LGA sessions0.10.20.40.1-0.4-0.5-0.4-0.3-0.2-0.5-0.2-0.7-0.2
Extinction: sum of active levers before priming0.10.10.70.90.0-0.1-0.10.30.5-0.10.40.20.1
Active lever presses in extinction session 60.20.10.50.70.30.30.20.50.50.30.40.10.2
Delta distance traveled before/after self-admin0.20.20.30.5-0.5-0.6-0.5-0.4-0.2-0.5-0.2-0.4-0.0
Delta ambulatory time before/after self-admin0.10.10.30.6-0.3-0.3-0.2-0.10.1-0.30.1-0.20.1
Time in closed arm before self-admin2.63.03.71.71.61.61.71.81.91.91.81.41.9
Time in closed arm after self-admin0.80.81.11.00.80.80.70.91.01.01.00.70.9
Time in open arm before self-admin2.02.12.4-1.2-1.4-1.4-1.4-1.5-1.5-1.5-1.5-1.4-1.4
Time in open arm after self-admin2.83.15.3-2.3-1.4-1.4-1.5-1.8-2.1-1.6-2.0-1.4-1.8
Sum of active levers in priming session hrs 5-60.90.91.5-0.4-1.1-1.2-1.2-0.8-0.6-1.2-0.6-0.9-1.0
Time to tail flick, vehicle, before self-admin3.03.04.81.11.91.91.81.71.51.91.62.21.5
Time to tail flick, vehicle, after self-admin4.75.05.72.22.42.32.42.11.92.42.22.22.3
Time to tail flick, test, before self-admin1.61.62.31.11.41.31.21.31.11.21.21.51.1
Time to tail flick, test, after self-admin2.32.43.11.21.81.71.61.61.41.61.41.81.4
Delta time to tail flick, vehicle, before/after SA0.10.10.40.60.30.30.30.30.30.30.30.10.5
Delta time to tail flick, test, before/after SA0.00.00.0-0.20.00.20.2-0.1-0.10.1-0.10.20.2
Ambulatory time before self-admin0.40.41.21.10.50.50.50.50.50.30.70.50.7
Ambulatory time after self-admin1.21.34.32.10.80.70.81.01.20.61.41.01.2
Total heroin consumption1.31.62.3-0.8-1.4-1.5-1.4-1.2-1.0-1.3-1.1-1.4-1.1
Area under the delay curve0.20.20.4-0.6-0.2-0.2-0.2-0.3-0.7-0.4-0.5-0.4-0.3
Delay disc. indifference point, 0s delay0.00.00.10.3-0.10.10.20.10.10.10.10.10.1
Delay disc. indifference point, 16s delay1.41.42.1-1.1-1.2-1.2-1.1-1.1-1.3-1.4-1.2-1.3-0.9
Delay disc. indifference point, 2s delay0.10.10.2-0.4-0.4-0.4-0.3-0.3-0.5-0.3-0.3-0.3-0.1
Delay disc. indifference point, 24s delay0.20.20.5-0.5-0.3-0.3-0.2-0.4-0.7-0.5-0.5-0.5-0.5
Delay disc. indifference point, 4s delay0.10.10.3-0.3-0.2-0.2-0.2-0.3-0.5-0.4-0.4-0.4-0.3
Delay disc. indifference point, 8s delay0.30.30.50.20.70.70.60.60.30.60.40.40.5
Delay discount exponential model param0.20.20.60.70.30.30.30.40.80.50.50.50.4
Delay discount hyperbolic model param0.10.20.50.60.20.20.20.30.70.40.40.40.3
Fecal boli incidents, locomotor time 16.46.98.7-1.8-2.8-2.9-2.8-2.7-2.4-2.9-2.5-3.0-2.3
Change in fecal boli incidents, locomotor task4.64.45.61.62.32.42.32.01.62.31.92.42.0
Time >=10cm from walls, locomotor time 10.10.10.2-0.0-0.2-0.3-0.2-0.2-0.1-0.4-0.1-0.40.1
Bouts of movement, locomotor time 10.40.41.0-0.2-0.7-0.8-0.6-0.7-0.5-0.7-0.5-1.0-0.3
Total resting periods, locomotor time 10.30.30.8-0.1-0.6-0.7-0.6-0.5-0.3-0.7-0.4-0.9-0.2
Rest time, locomotor task time 10.20.30.60.3-0.4-0.6-0.6-0.4-0.4-0.8-0.2-0.80.1
Distance moved, locomotor task time 11.71.82.51.01.31.51.41.51.41.61.31.41.1
Vertical activity count, locomotor time 10.10.10.4-0.10.10.50.40.30.30.60.20.3-0.0
Time >=10cm from walls, locomotor time 26.67.07.32.62.52.72.62.72.72.62.72.72.7
Bouts of movement, locomotor time 20.20.20.3-0.5-0.4-0.5-0.6-0.20.1-0.5-0.2-0.4-0.6
Total resting periods, locomotor time 20.10.10.2-0.4-0.3-0.4-0.5-0.20.1-0.4-0.2-0.3-0.4
Rest time, locomotor task time 22.02.32.6-1.5-1.4-1.6-1.6-1.5-1.5-1.6-1.5-1.6-1.3
Distance moved, locomotor task time 24.85.66.72.62.22.42.32.52.32.32.52.22.4
Vertical activity count, locomotor time 22.42.62.91.71.41.71.61.71.71.71.71.61.5
Weight adjusted by age2.32.63.2-1.7-1.5-1.5-1.6-1.6-1.4-1.6-1.6-1.7-1.8
Seeking ratio, delayed vs. immediate footshock0.20.30.40.10.50.50.50.70.60.40.50.50.4
Locomotion in novel chamber0.50.60.90.40.90.80.90.60.50.90.60.90.7
Locomotion in novel chamber post-restriction0.91.11.3-1.1-0.9-1.0-1.1-1.1-1.1-1.1-1.1-0.9-1.0
Progressive ratio0.30.40.60.60.60.70.50.70.60.60.80.40.4
Food seeking constrained by brief footshock0.91.11.31.10.91.11.11.01.01.01.01.01.1
Seeking ratio, punishment vs. effort0.20.20.4-0.6-0.4-0.3-0.3-0.6-0.6-0.4-0.6-0.3-0.4
Run reversals in cocaine runway, females0.20.20.60.60.20.20.20.40.80.30.50.20.5
Run reversals in cocaine runway, males5.35.15.9-2.3-2.3-2.3-2.4-2.1-2.0-2.4-2.2-2.3-2.2
Latency to leave start box in cocaine runway0.50.51.4-1.1-0.5-0.6-0.6-0.6-0.7-0.4-0.6-0.5-1.2
Latency to leave start box in cocaine runway, F0.40.51.6-1.1-0.4-0.5-0.5-0.5-0.6-0.2-0.6-0.6-1.3
Latency to leave start box in cocaine runway, M0.20.20.3-0.2-0.5-0.5-0.4-0.4-0.3-0.5-0.4-0.3-0.5
Cd content in liver1.11.21.50.81.21.11.11.11.21.21.11.20.9
Co content in liver1.21.41.7-1.2-1.1-1.2-1.2-1.3-1.3-1.1-1.3-1.2-1.0
Cu content in liver0.20.30.4-0.4-0.5-0.5-0.5-0.5-0.6-0.5-0.5-0.6-0.4
Fe content in liver0.40.40.5-0.6-0.7-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.6
K content in liver2.92.93.4-1.7-1.7-1.7-1.7-1.6-1.5-1.7-1.7-1.8-1.8
Mg content in liver1.71.82.1-1.2-1.4-1.4-1.4-1.3-1.2-1.4-1.3-1.5-1.2
Mn content in liver1.71.92.4-1.0-1.5-1.5-1.5-1.3-1.3-1.5-1.3-1.5-1.4
Na content in liver0.00.00.10.3-0.2-0.3-0.3-0.10.1-0.3-0.0-0.30.1
Rb content in liver1.21.51.8-1.0-1.3-1.3-1.4-1.3-1.1-1.3-1.2-1.3-1.0
Se content in liver3.44.25.7-2.4-1.9-1.9-1.9-2.0-2.2-1.9-2.2-2.0-1.9
Sr content in liver0.10.10.2-0.4-0.3-0.3-0.3-0.3-0.1-0.3-0.3-0.3-0.3
Zn content in liver0.10.10.2-0.2-0.4-0.3-0.3-0.3-0.4-0.4-0.3-0.4-0.3