Hub : Genes

Lrrc57

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA intron excision ratio chr3:107552773:107553023 0.16 0.1 6.9e-03 0.02 0.05 0.06 0.02 3.1e-02 1.2e-03 2.6e-04 1.9e-02
2 Brain gene expression ENSRNOG00000009143 0.15 0.07 6.9e-13 0.13 0.14 0.13 0.13 4.5e-12 1.2e-12 2.5e-12 2.2e-12
3 Brain mRNA stability ENSRNOG00000009143 0.03 0.02 1.0e-02 0.03 0.01 0.01 0.02 1.7e-03 2.0e-02 1.7e-02 1.0e-02
4 IL gene expression ENSRNOG00000009143 0.39 0.13 4.4e-05 0.07 0.06 0.02 0.05 8.4e-03 1.9e-02 8.7e-02 2.7e-02
5 IL mRNA stability ENSRNOG00000009143 0.15 0.08 5.5e-03 0.03 0.01 -0.01 0 5.5e-02 1.8e-01 8.9e-01 3.1e-01
6 Liver gene expression ENSRNOG00000009143 0.06 0.03 1.6e-07 0.06 0.05 0.05 0.05 2.2e-07 1.5e-06 1.4e-06 1.5e-06
7 Liver mRNA stability ENSRNOG00000009143 0.07 0.03 5.4e-09 0.03 0.06 0.05 0.04 1.3e-04 3.6e-07 1.2e-06 3.4e-05
8 NAcc gene expression ENSRNOG00000009143 0.09 0.05 1.6e-03 0.03 0.02 0.01 0.03 1.3e-03 7.1e-03 2.3e-02 1.9e-03
9 OFC gene expression ENSRNOG00000009143 0.28 0.12 4.2e-04 0.17 0.12 0.09 0.12 7.1e-05 8.1e-04 3.1e-03 1.1e-03
10 PL gene expression ENSRNOG00000009143 0.06 0.03 5.5e-04 0 0.02 0.01 0.01 2.4e-01 1.8e-02 4.2e-02 1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail1.44.517.32.00.90.14.2-3.4-0.1-2.9-0.3-0.11.5
BMI without tail1.63.311.81.30.1-1.03.0-3.4-0.5-2.90.4-0.50.5
Body weight1.45.826.51.31.4-0.15.2-3.80.4-3.0-0.90.41.9
Epididymis fat weight0.10.31.1-0.60.20.11.0-0.50.1-0.3-0.90.10.2
Glucose0.10.20.60.40.40.30.4-0.80.4-0.2-0.00.40.3
Heart weight1.82.612.0-0.51.2-0.23.5-2.50.8-1.4-0.70.81.5
Left kidney weight1.33.76.6-2.0-1.6-2.61.8-2.2-1.7-2.4-1.6-1.7-1.4
Right kidney weight2.36.512.1-2.1-2.2-3.52.4-2.7-2.5-3.3-2.1-2.5-1.8
Tail length0.10.41.20.40.60.00.9-1.10.7-0.40.60.70.6
Length with tail0.20.94.1-0.50.6-0.52.0-1.50.5-0.8-0.30.50.8
Length without tail0.30.73.3-0.20.80.31.8-0.60.4-0.4-0.90.41.0
Liver weight, left2.54.010.22.71.4-0.02.8-3.20.5-2.41.80.51.9
Liver weight, right0.91.53.70.1-0.9-1.51.4-1.6-1.3-1.9-0.5-1.3-0.6
Parametrial fat weight0.10.20.9-0.50.0-0.90.9-0.5-0.1-0.5-0.0-0.10.2
Retroperitoneal fat weight1.34.418.40.22.31.24.3-1.91.7-0.8-1.11.72.6
Intraocular pressure0.81.14.3-0.3-0.70.4-1.52.1-0.41.2-1.2-0.4-0.9
Extensor digitorum longus weight0.10.51.00.7-0.6-0.10.2-1.0-0.8-1.0-0.5-0.8-0.5
Soleus weight0.41.13.00.81.31.70.30.31.20.90.31.21.2
Tibialis anterior weight0.82.65.60.52.22.41.2-0.02.01.00.42.02.2
Tibia length0.72.06.6-2.6-1.1-1.91.0-0.2-0.9-0.6-2.1-0.9-1.0
Number of licking bursts0.60.72.81.70.10.7-0.6-0.6-0.1-0.51.5-0.10.2
Food consumed during 24 hour testing period0.40.41.81.20.1-0.2-0.1-0.80.0-0.51.30.00.2
Times rat made contact with spout0.30.31.3-0.3-0.6-0.40.3-0.1-0.6-0.3-1.1-0.6-0.5
Mean time between licks in bursts0.40.61.50.3-0.9-0.8-1.20.1-0.8-0.30.7-0.8-1.0
Mean num. licks in bursts0.70.83.9-1.6-0.1-0.60.90.50.10.4-2.00.1-0.1
Std. dev. time between licks in bursts1.11.32.50.3-1.0-1.00.9-1.1-1.5-1.6-0.9-1.5-0.8
Water consumed over 24 hours0.30.41.10.10.61.1-0.10.60.70.9-0.30.70.5
Indifference point 0 sec1.21.912.9-1.5-0.6-0.21.50.6-0.6-0.2-3.6-0.6-0.5
Indifference point AUC0.91.03.1-0.60.30.8-1.61.80.61.70.30.60.0
Indifference point function ln k1.41.96.71.5-0.0-0.62.0-2.6-0.6-2.30.4-0.60.3
Indifference point function log k1.41.96.71.5-0.0-0.62.0-2.6-0.6-2.30.4-0.60.3
Delay discounting total patch changes 0 sec1.01.611.7-1.2-0.50.11.40.7-0.5-0.0-3.4-0.5-0.4
Delay discounting total patch changes 12 sec1.41.85.4-1.90.40.90.12.00.71.8-2.30.70.2
Delay discounting total patch changes 18 sec1.01.33.9-1.50.10.7-0.62.00.71.7-1.30.7-0.1
Delay discounting total patch changes 24 sec0.50.62.8-0.2-0.2-0.61.7-0.4-0.5-0.9-1.1-0.50.1
Delay discounting total patch changes 6 sec0.81.23.5-1.50.00.8-0.41.60.51.4-1.90.5-0.2
Delay discounting time to switch 0 sec0.71.12.6-1.40.70.9-0.01.61.01.6-0.91.00.6
Delay discounting water rate 0 sec0.40.61.21.10.80.80.9-1.10.5-0.40.00.50.8
Delay discounting water rate 12 sec1.52.29.13.00.91.00.0-1.80.5-0.92.40.51.0
Delay discounting water rate 18 sec1.21.64.92.2-0.5-0.30.1-2.0-1.0-1.91.2-1.0-0.3
Delay discounting water rate 24 sec1.42.05.32.31.62.10.5-0.91.20.21.01.21.6
Delay discounting water rate 6 sec1.21.74.21.91.31.6-0.7-0.51.20.62.11.21.2
Locomotor activity0.10.10.3-0.1-0.4-0.2-0.20.5-0.50.10.0-0.5-0.4
Locomotor testing distance0.30.51.1-0.7-0.6-0.0-0.91.1-0.50.6-0.6-0.5-0.7
Locomotor testing rearing0.61.02.9-1.00.30.6-1.21.60.81.7-0.00.80.0
Light reinforcement 12.44.415.1-3.21.11.21.61.91.52.1-3.91.50.9
Light reinforcement 20.81.03.0-1.10.30.6-0.81.50.81.7-1.00.80.0
Reaction time number correct1.31.97.31.21.00.52.0-2.70.4-1.50.80.41.2
Reaction time mean minus median0.30.41.80.40.40.21.3-1.00.1-0.7-0.30.10.7
Reaction time mean minus median AUC0.60.83.7-0.10.3-0.21.9-1.40.0-1.0-0.90.00.6
Reaction time num false alarms0.40.53.4-1.8-0.3-0.1-0.40.70.00.6-0.60.0-0.5
Reaction time num false alarms AUC0.30.51.9-1.40.20.5-0.40.80.51.0-0.30.50.0
Reaction time trials correct on left1.31.97.31.21.00.52.0-2.70.4-1.50.80.41.2
Reaction time trials on left1.31.87.11.21.00.52.0-2.70.4-1.50.70.41.2
Reaction time mean1.11.53.90.71.32.0-0.30.91.41.30.51.41.3
Reaction time mean AUC0.70.92.80.71.11.7-0.10.51.10.90.31.11.1
Median of all reaction times1.62.15.00.51.32.2-1.11.61.62.00.61.61.1
Reaction time omissions0.40.52.8-1.7-0.1-0.10.50.4-0.00.3-1.4-0.0-0.2
Reaction time false alarm rate0.81.13.6-1.7-0.30.1-1.21.90.21.4-0.70.2-0.6
Reaction time premature initiation rate1.41.94.8-1.41.20.8-0.01.71.72.2-0.61.71.0
Reaction time premature initiations1.11.63.3-0.81.61.00.90.31.81.3-0.21.81.6
Std. dev. reaction times0.30.41.30.50.60.81.2-0.50.3-0.2-0.70.30.8
Reaction time trials completed1.31.87.11.21.00.52.0-2.70.4-1.50.70.41.2
Reaction time trials AUC1.42.16.31.21.40.92.1-2.50.8-1.20.80.81.6
Social response proportion4.85.210.4-1.62.92.31.10.93.22.5-0.33.22.7
Social responses4.86.213.2-1.42.53.1-0.22.43.13.6-1.03.12.1
Social time1.31.73.61.21.61.90.70.51.50.90.41.51.6
Conditioned locomotion0.60.72.8-0.20.4-0.21.6-1.70.1-1.1-0.20.10.5
Cocaine response after cond. corrected1.31.43.71.9-0.8-0.0-1.6-0.6-0.9-0.81.9-0.9-0.8
Cocaine response after cond. not corrected1.71.94.41.8-1.2-0.6-1.8-0.7-1.3-1.12.1-1.3-1.1
Cocaine response before conditioning0.50.72.0-1.4-0.9-1.2-0.30.6-0.50.1-0.7-0.5-0.9
Saline control response1.01.44.8-1.50.8-0.02.2-0.10.70.2-2.00.70.9
Condit. Reinf. active minus inactive responses2.43.06.2-0.12.41.62.1-0.22.20.90.02.22.5
Condit. Reinf. active-inactive response ratio1.92.04.20.12.01.41.6-0.31.90.70.31.92.1
Condit. Reinf. active responses2.73.87.5-0.32.71.92.4-0.12.51.1-0.42.52.7
Condit. Reinf. inactive responses1.31.62.7-0.61.61.41.60.41.40.9-1.11.41.6
Condit. Reinf. lever presses1.11.52.6-0.61.41.31.60.61.20.9-1.41.21.4
Condit. Reinf. lever reinforcers received2.73.97.2-0.72.61.92.30.22.51.3-0.62.52.7
Pavlov. Cond. lever latency1.82.56.41.1-1.6-1.6-2.5-0.1-1.5-0.72.1-1.5-1.7
Pavlov. Cond. magazine entry latency3.43.95.5-1.72.12.31.21.42.32.3-1.82.31.8
Pavlov. Cond. change in total contacts2.63.76.0-1.32.42.11.80.82.51.8-1.02.52.3
Pavlov. Cond. index score3.44.46.7-1.42.42.61.90.92.52.0-1.82.52.3
Pavlov. Cond. latency score2.93.75.5-1.42.22.31.70.92.31.9-1.62.32.0
Pavlov. Cond. lever contacts2.23.06.2-1.01.91.92.50.51.71.1-2.11.72.0
Pavlov. Cond. magazine entry number2.83.45.41.5-2.1-2.3-1.3-0.9-2.3-1.91.4-2.3-1.8
Pavlov. Cond. intertrial magazine entries1.62.13.91.3-1.6-1.6-0.2-1.2-1.9-2.00.4-1.9-1.3
Pavlov. Cond. lever-magazine prob. diff.3.44.46.8-1.42.42.61.80.92.52.0-1.72.52.2
Pavlov. Cond. response bias3.65.07.0-1.22.62.72.60.82.51.7-2.12.52.6
Conditioned reinforcement - actives0.40.41.5-1.2-0.4-0.60.20.5-0.20.2-1.2-0.2-0.4
Conditioned reinforcement - inactives0.10.20.5-0.10.40.40.1-0.10.70.50.00.70.3
Conditioned locomotion1.51.85.1-2.2-1.2-1.5-0.11.3-0.90.4-2.3-0.9-1.3
Intermittent access intake day 1-15 change0.90.93.41.80.10.2-0.1-1.4-0.1-0.91.5-0.10.1
Intermittent access intake escalation0.90.93.31.70.40.3-0.2-1.30.4-0.51.80.40.4
Intermittent access intake escalation 22.22.27.12.4-0.7-0.6-1.0-1.9-0.8-1.52.7-0.8-0.7
Intermitt. access day 1 inactive lever presses0.70.82.6-1.60.5-0.31.20.40.70.5-1.20.70.5
Intermitt. access day 15 inactive lever presses0.70.82.4-1.50.50.2-0.10.81.01.3-0.71.00.2
Intermitt. access escalation Index0.50.41.20.20.81.10.30.40.70.7-0.50.70.8
Intermittent access day 1 total infusions0.91.02.5-1.50.40.50.01.30.81.4-1.60.80.3
Intermittent access day 15 total infusions0.20.20.5-0.30.40.4-0.10.20.70.7-0.20.70.3
Intermittent access terminal intake (last 3 days)0.20.20.40.60.40.4-0.1-0.50.50.10.50.50.3
Intermittent access total infusions0.20.20.4-0.60.40.10.20.20.60.6-0.50.60.3
Intermittent access day 1 locomotion1.11.16.0-1.9-0.3-0.50.80.8-0.20.4-2.5-0.2-0.3
Intermittent access day 15 total locomotion0.70.71.6-0.31.10.41.0-0.51.30.30.21.31.1
Intermittent access total locomotion0.30.31.0-1.00.3-0.30.30.40.50.6-0.70.50.2
Intermittent access standard deviation0.40.41.41.20.40.10.3-1.00.3-0.51.00.30.4
Cocaine induced anxiety1.72.08.8-3.0-1.2-2.10.4-0.3-0.8-0.4-1.4-0.8-1.2
Post-drug Anxiety0.40.51.3-0.8-0.6-1.10.4-1.0-0.6-0.90.1-0.6-0.5
Baseline Anxiety0.60.62.51.60.61.00.3-0.60.3-0.40.80.30.7
Lifetime Intake0.10.10.2-0.20.10.1-0.10.40.30.5-0.50.30.1
Incentive Sensitization - Responses0.10.10.3-0.10.40.4-0.00.10.50.4-0.10.50.2
Incentive Sensitization - Breakpoint0.20.20.5-0.30.50.50.00.20.70.6-0.30.70.4
Progressive ratio test 1 active lever presses1.11.12.1-1.01.00.80.31.01.31.4-1.01.30.8
Progressive ratio test 1 breakpoint0.80.91.8-0.90.90.60.20.81.31.3-0.61.30.7
Progressive ratio test 1 inactive lever presses1.31.43.3-1.80.80.70.01.31.41.8-1.01.40.5
Progressive ratio test 2 active lever presses1.61.73.7-1.31.21.0-0.21.21.81.9-0.61.80.9
Progressive ratio test 2 breakpoint2.12.44.8-1.31.51.40.11.42.12.2-1.02.11.2
Progressive ratio test 2 inactive lever presses0.70.81.7-1.30.70.60.10.71.21.3-0.91.20.5
Total sessions with >9 infusions1.31.42.8-1.1-1.4-1.3-0.30.6-1.4-0.3-1.7-1.4-1.4
Short access day 1 total inactive lever presses0.10.10.50.10.20.10.7-0.6-0.0-0.5-0.0-0.00.3
Short access day 10 total inactive lever presses0.91.05.0-2.20.6-0.90.8-0.61.00.30.11.00.5
Short access day 1 total infusions0.30.40.7-0.0-0.7-0.4-0.80.8-0.70.2-0.4-0.7-0.7
Short access day 10 total infusions0.20.21.1-0.50.3-0.10.70.30.30.3-1.00.30.4
Short access total infusions0.10.10.20.4-0.00.10.00.4-0.20.1-0.5-0.20.0
Short access day 1 locomotion0.30.41.3-0.50.10.3-0.31.20.20.9-0.90.20.1
Short access day 10 total locomotion2.32.54.70.6-1.9-2.0-0.7-0.9-2.2-1.80.5-2.2-1.7
Short access total locomotion0.80.82.5-1.2-0.7-1.10.30.6-0.8-0.1-1.6-0.8-0.7
Compulsive drug intake1.21.22.61.61.21.60.1-0.41.00.21.41.01.2
One hour access (0.3 mA shock)1.11.32.60.81.31.2-0.4-0.31.60.91.41.61.1
One hour access (shock baseline)0.60.72.4-1.60.2-0.2-0.30.90.71.2-1.00.7-0.1
Number of responses in last shaping day0.60.61.9-1.1-0.40.3-0.41.1-0.40.6-1.4-0.4-0.5
Context. condit. distance diff. score0.70.81.70.21.10.51.3-1.31.0-0.20.01.01.1
Locomotion velocity, session 12.12.25.0-1.0-1.9-1.4-2.21.5-1.40.5-0.2-1.4-2.1
Locomotion distance, session 11.21.53.0-1.2-1.5-1.5-1.70.9-1.10.3-0.1-1.1-1.7
Locomotion velocity, session 22.32.74.8-0.1-2.0-2.2-0.1-1.3-2.1-2.0-0.2-2.1-1.8
Locomotion distance, session 20.40.51.2-0.4-0.8-1.1-1.0-0.2-0.6-0.20.8-0.6-0.8
Locomotion velocity, session 31.21.42.90.6-1.6-0.7-1.0-0.1-1.7-0.9-0.5-1.7-1.6
Locomotion distance, session 30.40.42.10.7-0.50.6-1.40.2-0.30.3-0.0-0.3-0.7
Stereotopy head waving bouts, day 31.01.13.6-0.6-0.7-0.81.5-0.7-1.0-1.1-1.9-1.0-0.5
Stereotopy head waving duration, day 32.22.75.70.1-1.3-1.71.9-1.6-1.9-2.4-1.5-1.9-0.9
Locomotion velocity, session 70.40.41.0-0.9-0.7-0.5-0.70.1-0.40.2-1.0-0.4-1.0
Locomotion distance, session 70.20.30.7-0.50.60.4-0.40.00.80.80.40.80.4
Stereotopy head waving bouts, day 70.20.20.4-0.10.40.60.40.50.40.4-0.70.40.4
Stereotopy head waving duration, day 70.20.30.80.10.10.70.00.90.20.5-0.90.20.1
Locomotion velocity, session 81.61.93.4-0.6-1.5-1.80.5-1.5-1.5-1.7-0.9-1.5-1.4
Locomotion distance, session 80.10.21.1-0.50.2-0.40.3-1.00.4-0.30.30.40.1
Degree of sensitization distance1.21.32.3-0.81.50.80.80.61.51.10.31.51.5
Degree of sensitization stereotypy0.80.91.8-0.20.71.3-0.41.21.11.4-0.41.10.6
Condit. Reinf. active minus inactive responses2.62.96.4-1.91.41.70.02.11.92.5-1.21.91.2
Condit. Reinf. active-inactive response ratio0.80.91.6-1.00.81.10.60.71.01.0-1.31.00.7
Condit. Reinf. active responses4.45.312.4-2.42.02.2-0.33.02.63.5-1.12.61.6
Condit. Reinf. inactive responses2.53.07.8-1.41.41.6-0.92.32.02.8-0.12.01.1
Incentive salience index mean2.93.58.4-2.41.41.5-0.52.62.02.9-1.02.01.0
Condit. Reinf. lever presses1.72.36.0-2.50.90.8-0.42.11.52.3-0.71.50.7
Time in familiar zone, hab. session 10.70.63.31.5-0.00.1-0.8-0.2-0.3-0.31.8-0.30.1
Time in novel zone, hab. session 11.00.94.7-1.50.30.41.00.20.60.5-2.20.60.2
Total zone transitions, hab. session 10.30.41.50.3-0.5-1.0-0.2-0.4-0.6-0.71.2-0.6-0.3
Total locomotion distance, hab. session 10.40.62.1-0.5-0.8-1.5-0.3-0.3-0.9-0.70.7-0.9-0.7
Locomotion velocity, hab. session 10.50.72.5-0.7-0.9-1.6-0.4-0.0-1.0-0.60.7-1.0-0.8
Time in familiar zone, hab. session 20.40.41.71.30.50.80.4-0.30.2-0.20.50.20.7
Time in novel zone, hab. session 20.60.62.4-1.6-0.6-0.80.10.1-0.20.0-1.3-0.2-0.7
Total zone transitions, hab. session 20.81.02.10.5-0.9-1.4-0.3-0.9-1.0-1.31.3-1.0-0.7
Total locomotion distance, hab. session 20.20.20.9-0.5-0.3-0.90.2-0.5-0.3-0.60.4-0.3-0.2
Locomotion velocity, hab. session 20.20.30.9-0.6-0.3-1.00.2-0.4-0.4-0.50.5-0.4-0.2
Novel to familiar place preference ratio0.70.72.6-1.10.50.11.6-0.10.40.1-1.50.40.6
Novelty place preference0.60.72.4-1.20.40.01.5-0.10.30.1-1.60.30.4
Time in novel zone, NPP test0.60.72.2-1.20.50.21.5-0.10.40.2-1.50.40.5
Total zone transitions, NPP test1.42.03.60.7-1.5-1.8-1.4-0.9-1.5-1.31.9-1.5-1.4
Total locomotion distance, NPP test1.82.56.1-0.5-1.9-2.5-0.9-0.9-1.8-1.50.7-1.8-1.8
Locomotion velocity, NPP test2.02.97.1-0.5-2.1-2.7-1.0-0.9-2.0-1.60.7-2.0-2.0
Pavlov. Cond. lever latency0.40.52.91.70.61.20.3-0.40.3-0.20.30.30.6
Pavlov. Cond. magazine entry latency2.12.711.0-3.30.90.41.01.41.51.8-2.01.50.7
Pavlov. Cond. change in total contacts0.50.63.0-1.70.5-0.30.20.01.00.70.01.00.4
Pavlov. Cond. index score0.70.95.3-2.30.1-0.40.01.00.51.0-0.80.5-0.1
Pavlov. Cond. latency score0.60.85.5-2.3-0.1-0.70.20.80.20.7-0.90.2-0.2
Pavlov. Cond. lever contacts0.50.52.9-1.7-0.5-1.1-0.30.5-0.20.2-0.2-0.2-0.6
Pavlov. Cond. magazine entry number1.41.78.02.8-0.5-0.1-0.6-1.1-1.0-1.41.7-1.0-0.3
Pavlov. Cond. intertrial magazine entries1.51.87.52.71.22.0-0.2-0.00.90.31.50.91.2
Pavlov. Cond. lever-magazine prob. diff.0.60.74.5-2.1-0.1-0.6-0.30.90.30.8-0.60.3-0.3
Pavlov. Cond. response bias0.91.25.3-2.30.50.1-0.11.11.11.5-0.61.10.3
Bone: apparent density0.50.93.11.20.0-0.31.1-1.8-0.4-1.50.7-0.40.2
Bone surface0.50.92.01.30.90.61.4-1.30.5-0.80.70.51.1
Bone volume0.50.82.11.50.70.81.2-1.20.3-0.80.40.30.8
Bone: connectivity density0.20.31.60.00.4-0.21.3-0.80.1-0.70.20.10.6
Bone: cortical apparent density1.51.94.30.61.52.1-0.51.11.71.70.61.71.3
Bone: cortical area0.40.62.10.70.10.11.4-1.1-0.2-1.1-0.6-0.20.3
Bone: cortical porosity2.83.05.60.2-2.2-2.4-1.6-0.6-2.1-1.40.7-2.1-2.2
Bone: cortical porosity2.12.34.4-0.0-2.0-2.1-0.8-0.6-1.9-1.4-0.1-1.9-1.9
Bone: cortical thickness0.30.51.40.3-0.4-0.41.0-1.1-0.6-1.2-0.6-0.6-0.3
Bone: cortical thickness1.31.58.52.90.40.80.1-1.1-0.0-1.01.7-0.00.6
Bone: cortical tissue density1.41.84.10.71.52.0-0.51.11.61.60.61.61.3
Bone: elastic displacement0.40.51.1-0.7-0.8-0.3-0.60.6-0.60.2-1.1-0.6-0.9
Bone: elastic work0.30.32.3-0.50.00.60.60.3-0.10.2-1.5-0.1-0.0
Bone: endosteal estimation0.20.41.31.10.60.50.3-0.50.4-0.20.80.40.6
Bone: endosteal perimeter0.00.10.20.50.30.30.00.10.30.10.20.30.2
Bone: final force0.50.81.6-0.11.11.30.8-0.21.20.7-0.81.21.0
Bone: final moment0.40.61.5-0.20.91.20.6-0.11.00.7-0.81.00.8
Bone: marrow area0.20.31.21.10.50.50.3-0.60.4-0.20.70.40.6
Bone: maximum diameter0.30.62.00.90.80.71.4-0.80.5-0.5-0.20.50.9
Bone: maximum force0.30.52.1-0.50.40.21.4-0.80.3-0.3-1.20.30.4
Bone: maximum moment0.20.41.5-0.60.20.01.2-0.70.1-0.3-1.20.10.2
Bone: minimum diameter1.12.04.20.4-1.4-1.50.9-1.2-1.8-2.1-0.9-1.8-1.2
Bone: periosteal estimation0.20.41.01.00.30.31.0-0.90.1-0.8-0.10.10.4
Bone: periosteal perimeter0.20.40.90.3-0.5-0.60.6-0.7-0.7-0.9-0.7-0.7-0.5
Bone: post-yield work0.40.51.8-0.2-0.6-1.3-0.2-0.7-0.6-0.80.8-0.6-0.5
Bone: stiffness0.30.41.8-0.40.6-0.01.4-0.80.4-0.4-0.50.40.6
Bone: tissue strength0.50.41.4-0.9-0.7-1.20.1-0.4-0.6-0.5-0.6-0.6-0.7
Bone: trabecular number0.91.55.21.20.80.21.6-2.30.3-1.41.20.31.0
Bone: trabecular spacing1.31.75.9-1.6-0.50.2-0.92.4-0.11.6-2.2-0.1-0.7
Bone: trabecular thickness0.91.13.61.90.91.2-0.2-0.40.60.01.80.60.9
Bone: trabecular tissue density1.21.69.21.5-0.2-0.6-2.0-0.60.1-0.13.00.1-0.3
Breakpoint value in progressive ratio session0.50.62.51.60.61.00.3-0.80.3-0.40.80.30.7
Distance traveled before self-admin0.20.20.60.30.30.10.7-0.60.2-0.50.20.20.4
Distance traveled after self-admin1.11.22.51.61.31.30.7-0.61.00.11.01.01.4
Delta time in closed arm before/after self-admin0.80.82.4-1.50.50.5-0.30.51.21.2-0.31.20.3
Delta time in open arm before/after self-admin1.61.53.61.91.10.51.2-1.90.7-0.91.40.71.2
Diff in mean of infusions in LGA sessions0.70.81.3-0.61.01.00.20.71.11.1-0.51.10.9
Extinction: sum of active levers before priming0.40.41.20.3-0.7-0.1-1.10.5-0.7-0.00.2-0.7-0.7
Active lever presses in extinction session 61.11.01.8-0.7-1.3-1.4-0.3-0.7-1.3-0.9-0.3-1.3-1.2
Delta distance traveled before/after self-admin0.30.40.70.60.70.8-0.10.40.60.60.40.60.7
Delta ambulatory time before/after self-admin0.50.51.3-0.50.80.8-0.10.90.81.1-0.20.80.7
Time in closed arm before self-admin0.60.73.10.40.10.8-1.11.80.11.2-0.30.10.0
Time in closed arm after self-admin2.02.15.4-1.20.91.6-0.92.21.42.3-0.91.40.6
Time in open arm before self-admin0.10.10.30.2-0.30.10.4-0.5-0.4-0.5-0.5-0.4-0.2
Time in open arm after self-admin1.61.86.62.10.4-0.01.5-2.6-0.0-1.71.0-0.00.6
Sum of active levers in priming session hrs 5-60.20.21.00.6-0.1-0.1-0.4-0.6-0.1-0.31.0-0.1-0.1
Time to tail flick, vehicle, before self-admin0.80.82.10.6-0.6-1.30.7-0.8-1.1-1.50.2-1.1-0.3
Time to tail flick, vehicle, after self-admin0.40.53.41.8-0.00.30.2-0.6-0.2-0.70.3-0.20.0
Time to tail flick, test, before self-admin0.20.20.9-0.60.4-0.10.9-0.10.30.1-0.70.30.4
Time to tail flick, test, after self-admin0.50.51.31.10.60.21.1-0.90.3-0.60.50.30.8
Delta time to tail flick, vehicle, before/after SA0.60.61.21.00.81.10.6-0.81.00.10.21.00.8
Delta time to tail flick, test, before/after SA0.20.21.51.20.00.20.3-0.2-0.2-0.50.2-0.20.1
Ambulatory time before self-admin0.10.10.2-0.0-0.2-0.30.5-0.3-0.3-0.5-0.4-0.3-0.1
Ambulatory time after self-admin0.50.51.10.40.81.0-0.30.30.90.80.70.90.7
Total heroin consumption1.11.32.2-0.1-1.5-1.3-0.7-0.8-1.4-1.20.5-1.4-1.4
Area under the delay curve3.74.09.20.6-2.1-2.20.3-1.3-3.0-2.7-0.2-3.0-1.7
Delay disc. indifference point, 0s delay1.61.73.5-1.3-1.4-1.3-0.40.8-1.9-0.3-1.5-1.9-1.4
Delay disc. indifference point, 16s delay3.13.17.71.1-2.1-1.5-0.7-0.5-2.8-1.9-0.1-2.8-1.9
Delay disc. indifference point, 2s delay0.20.20.8-0.90.4-0.10.6-0.30.20.0-0.30.20.4
Delay disc. indifference point, 24s delay1.31.22.7-0.3-1.3-1.3-1.20.6-1.6-0.30.1-1.6-1.3
Delay disc. indifference point, 4s delay2.32.55.2-0.2-1.7-2.20.1-0.9-2.3-1.9-0.1-2.3-1.5
Delay disc. indifference point, 8s delay4.64.810.50.9-2.2-2.01.0-1.7-3.2-3.2-0.7-3.2-1.7
Delay discount exponential model param3.23.47.7-0.71.92.1-0.21.22.82.4-0.12.81.6
Delay discount hyperbolic model param2.82.96.6-0.31.72.1-0.31.22.62.30.12.61.4
Fecal boli incidents, locomotor time 11.01.01.90.8-1.3-0.7-1.20.6-1.4-0.30.2-1.4-1.4
Change in fecal boli incidents, locomotor task1.00.93.5-0.10.8-0.11.9-1.70.5-0.90.00.50.9
Time >=10cm from walls, locomotor time 10.50.51.31.10.71.1-0.0-0.00.70.40.60.70.6
Bouts of movement, locomotor time 10.91.03.60.5-1.1-0.2-1.91.3-1.00.40.4-1.0-1.2
Total resting periods, locomotor time 10.80.83.60.0-0.70.1-1.91.5-0.50.90.3-0.5-0.9
Rest time, locomotor task time 10.10.10.20.40.20.10.1-0.10.30.20.30.30.3
Distance moved, locomotor task time 10.60.61.9-0.9-0.00.7-0.41.30.21.0-1.40.2-0.2
Vertical activity count, locomotor time 10.50.51.10.41.00.90.7-0.00.70.10.10.71.0
Time >=10cm from walls, locomotor time 23.03.216.5-0.21.40.14.1-2.30.8-1.5-1.10.81.8
Bouts of movement, locomotor time 20.80.92.40.91.21.51.1-0.20.80.10.10.81.3
Total resting periods, locomotor time 20.80.92.50.91.21.60.9-0.20.90.10.30.91.3
Rest time, locomotor task time 21.11.36.6-0.2-0.6-0.2-2.61.20.01.31.40.0-0.8
Distance moved, locomotor task time 20.70.84.2-1.00.30.01.6-0.00.2-0.2-2.00.20.4
Vertical activity count, locomotor time 22.02.27.40.41.81.32.7-1.11.4-0.4-1.01.42.0
Weight adjusted by age0.40.51.9-1.1-0.4-0.60.7-0.1-0.4-0.2-1.4-0.4-0.4
Seeking ratio, delayed vs. immediate footshock1.72.04.2-0.01.91.31.0-0.62.00.70.32.01.9
Locomotion in novel chamber0.20.21.3-0.2-0.20.00.6-0.2-0.2-0.3-1.1-0.2-0.2
Locomotion in novel chamber post-restriction2.02.45.72.41.30.41.8-2.10.3-1.71.50.31.7
Progressive ratio0.60.62.41.60.70.20.5-0.50.3-0.31.40.30.9
Food seeking constrained by brief footshock0.10.21.1-1.0-0.1-0.30.2-0.1-0.20.0-0.6-0.2-0.1
Seeking ratio, punishment vs. effort0.81.04.3-2.1-0.6-0.1-0.60.9-0.30.7-1.7-0.3-0.8
Run reversals in cocaine runway, females0.70.73.01.10.30.00.0-1.30.3-0.61.70.30.4
Run reversals in cocaine runway, males0.50.52.1-0.1-0.6-0.2-1.41.00.30.9-0.20.3-0.9
Latency to leave start box in cocaine runway0.80.91.8-0.11.31.10.70.21.10.80.11.11.3
Latency to leave start box in cocaine runway, F0.10.10.20.0-0.3-0.5-0.10.1-0.4-0.30.0-0.4-0.1
Latency to leave start box in cocaine runway, M4.34.18.2-0.62.62.31.30.42.91.9-0.12.92.5
Cd content in liver0.20.20.70.80.0-0.00.6-0.6-0.3-0.70.1-0.30.1
Co content in liver0.91.01.80.5-1.4-1.1-0.9-0.4-1.3-0.90.2-1.3-1.3
Cu content in liver0.60.72.91.70.30.4-0.7-0.50.3-0.11.70.30.3
Fe content in liver3.64.39.4-0.72.12.7-0.52.52.53.1-0.02.51.8
K content in liver0.80.82.21.2-0.2-0.60.4-1.5-0.5-1.41.1-0.50.0
Mg content in liver1.51.55.22.30.0-0.20.4-2.2-0.4-1.61.4-0.40.2
Mn content in liver0.50.51.0-0.3-0.8-1.00.4-0.6-0.8-0.9-0.7-0.8-0.7
Na content in liver0.70.73.0-0.10.70.2-0.70.40.90.81.70.90.7
Rb content in liver1.92.48.61.9-0.6-0.71.5-2.9-1.1-2.6-0.0-1.1-0.3
Se content in liver0.00.00.20.2-0.00.10.0-0.40.0-0.2-0.00.0-0.1
Sr content in liver0.60.61.5-0.2-1.0-1.2-0.3-0.1-1.0-0.70.1-1.0-0.9
Zn content in liver0.40.53.10.80.5-0.1-0.1-0.40.4-0.11.80.40.6