Hub : Genes

Atp6v1d

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009080 0.11 0.06 1.4e-10 0.08 0.08 0.07 0.07 6.2e-09 1.6e-09 4.2e-08 7.6e-08
2 BLA gene expression ENSRNOG00000009080 0.54 0.13 0.0e+00 0.29 0.3 0.3 0.3 3.8e-16 8.7e-17 1.7e-16 2.3e-16
3 Brain alternative polyA ENSRNOT00000012101 0.11 0.06 2.1e-05 0.08 0.06 0.06 0.07 8.3e-08 2.3e-06 2.1e-06 8.4e-07
4 Brain gene expression ENSRNOG00000009080 0.55 0.11 0.0e+00 0.54 0.58 0.59 0.59 8.1e-59 2.1e-66 6.3e-67 2.3e-67
5 Brain mRNA stability ENSRNOG00000009080 0.09 0.05 8.3e-04 0.01 0.04 0.02 0.03 1.4e-02 3.0e-04 4.6e-03 7.8e-04
6 Eye gene expression ENSRNOG00000009080 0.35 0.18 4.1e-03 -0.02 0.1 0.06 0.03 6.5e-01 1.5e-02 3.8e-02 1.3e-01
7 IL gene expression ENSRNOG00000009080 0.58 0.14 6.0e-12 0.39 0.4 0.36 0.35 1.6e-10 1.6e-10 1.6e-09 3.0e-09
8 LHb gene expression ENSRNOG00000009080 0.46 0.14 1.8e-08 0.32 0.3 0.31 0.31 2.2e-08 6.7e-08 4.5e-08 4.9e-08
9 Liver gene expression ENSRNOG00000009080 0.09 0.05 1.0e-09 0.07 0.07 0.08 0.06 7.8e-08 1.9e-08 6.4e-09 1.4e-07
10 NAcc alternative polyA ENSRNOT00000012101 0.1 0.06 2.7e-04 0.06 0.05 0.03 0.04 3.8e-05 1.1e-04 4.6e-03 5.3e-04
11 NAcc gene expression ENSRNOG00000009080 0.32 0.12 0.0e+00 0.2 0.23 0.24 0.23 8.1e-15 3.8e-17 8.8e-18 5.9e-17
12 OFC gene expression ENSRNOG00000009080 0.6 0.14 8.6e-11 0.28 0.3 0.3 0.26 1.7e-07 8.1e-08 9.0e-08 9.2e-07
13 PL gene expression ENSRNOG00000009080 0.41 0.13 0.0e+00 0.32 0.34 0.35 0.35 5.8e-25 1.9e-26 3.6e-27 2.3e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.96.110.41.52.53.22.3-2.72.12.21.61.73.12.72.33.2
BMI without tail0.71.43.90.40.91.80.7-1.80.70.60.30.22.00.90.72.0
Body weight1.66.729.9-0.31.94.31.5-5.50.71.20.3-0.34.41.51.42.7
Epididymis fat weight0.20.40.8-0.9-0.50.0-0.7-0.8-0.7-0.6-0.9-0.70.4-0.6-0.40.2
Glucose0.81.25.90.3-0.8-1.9-0.62.4-0.2-0.5-0.10.3-1.6-0.5-0.5-1.1
Heart weight1.82.65.0-1.2-2.0-0.7-1.90.2-1.5-2.1-2.2-1.8-0.5-1.8-2.0-1.2
Left kidney weight0.20.52.0-1.4-0.4-0.6-0.7-0.5-1.2-0.4-0.6-0.8-0.3-0.5-0.40.8
Right kidney weight0.20.52.0-1.2-0.2-1.1-0.4-0.1-0.9-0.1-0.2-0.5-0.4-0.1-0.11.4
Tail length0.61.75.6-1.8-0.60.6-1.0-2.4-1.4-1.0-1.2-2.01.1-1.2-0.90.4
Length with tail0.62.214.6-1.60.41.80.0-3.8-0.90.0-0.4-1.42.2-0.30.10.6
Length without tail1.12.411.0-0.41.52.11.2-3.30.41.30.80.12.21.11.31.2
Liver weight, left1.01.72.9-0.1-1.6-1.1-1.41.7-0.7-1.5-1.3-0.6-1.2-1.4-1.5-1.6
Liver weight, right0.30.51.3-0.9-0.7-1.0-0.70.5-1.0-0.6-0.5-0.7-1.2-0.7-0.6-0.1
Parametrial fat weight0.20.31.3-1.1-0.10.1-0.3-0.9-0.8-0.2-0.4-0.70.1-0.4-0.20.2
Retroperitoneal fat weight0.72.25.31.31.42.31.4-1.41.51.21.01.22.21.61.20.7
Intraocular pressure3.65.18.22.42.50.72.60.12.62.62.72.91.12.52.71.7
Extensor digitorum longus weight0.31.05.50.30.81.30.6-1.30.50.50.30.01.21.00.62.3
Soleus weight0.72.212.0-1.20.72.30.3-3.5-0.50.3-0.3-1.11.80.50.21.8
Tibialis anterior weight2.07.026.20.32.04.51.6-5.11.11.30.5-0.24.51.91.53.0
Tibia length0.30.71.80.61.0-0.11.00.00.71.11.20.90.30.80.91.3
Number of licking bursts1.72.010.91.0-0.8-2.2-0.53.30.2-0.40.20.8-2.1-0.5-0.6-1.4
Food consumed during 24 hour testing period0.40.51.00.30.81.00.6-1.00.50.60.50.31.00.70.70.9
Times rat made contact with spout0.50.61.7-1.0-0.40.8-0.6-1.3-0.8-0.6-0.9-1.10.5-0.5-0.50.7
Mean time between licks in bursts0.81.14.7-0.1-0.3-2.0-0.22.1-0.20.00.30.4-2.2-0.1-0.0-0.6
Mean num. licks in bursts2.12.514.2-1.50.62.40.2-3.8-0.60.2-0.5-1.32.20.20.41.8
Std. dev. time between licks in bursts1.01.32.9-1.5-0.9-1.7-1.00.7-1.4-0.7-0.8-1.0-1.7-1.1-0.6-0.6
Water consumed over 24 hours0.70.82.80.70.71.70.6-1.30.80.40.30.21.50.90.50.6
Indifference point 0 sec1.11.84.3-0.4-1.60.3-1.7-0.3-0.9-2.0-2.1-1.30.6-1.5-1.6-1.1
Indifference point AUC0.00.10.30.2-0.20.2-0.00.10.1-0.2-0.20.10.3-0.2-0.2-0.5
Indifference point function ln k0.10.10.40.3-0.20.6-0.1-0.40.1-0.3-0.3-0.20.3-0.0-0.3-0.3
Indifference point function log k0.10.10.40.3-0.20.6-0.1-0.40.1-0.3-0.3-0.20.3-0.0-0.3-0.3
Delay discounting total patch changes 0 sec1.11.74.0-0.2-1.60.3-1.6-0.2-0.7-2.0-2.0-1.20.6-1.5-1.6-1.4
Delay discounting total patch changes 12 sec0.40.61.3-0.7-0.70.3-0.9-0.7-0.7-1.0-1.1-0.90.6-0.9-0.7-0.1
Delay discounting total patch changes 18 sec0.81.12.5-0.7-1.20.4-1.3-0.6-0.8-1.5-1.6-1.20.6-1.1-1.10.1
Delay discounting total patch changes 24 sec0.50.71.4-0.9-0.7-0.1-1.1-0.9-0.8-1.0-1.2-0.90.5-0.9-0.50.0
Delay discounting total patch changes 6 sec0.60.92.0-0.3-1.2-0.0-1.20.2-0.7-1.4-1.4-0.90.3-1.2-1.2-0.8
Delay discounting time to switch 0 sec0.60.93.0-1.7-0.2-1.4-0.60.3-1.3-0.0-0.1-0.6-1.3-0.20.11.7
Delay discounting water rate 0 sec0.91.44.81.40.82.10.9-1.41.40.50.40.72.20.80.6-0.2
Delay discounting water rate 12 sec0.60.82.61.40.51.60.6-0.61.20.30.40.51.60.30.3-1.0
Delay discounting water rate 18 sec2.33.16.21.11.92.31.8-2.51.61.71.41.12.51.61.80.2
Delay discounting water rate 24 sec2.33.28.62.01.52.81.6-1.92.11.21.01.22.91.61.4-0.1
Delay discounting water rate 6 sec0.50.72.7-0.1-0.31.3-0.3-1.7-0.2-0.6-0.7-0.91.4-0.7-0.6-0.9
Locomotor activity1.52.310.2-0.11.52.41.1-3.20.61.20.70.32.01.21.40.9
Locomotor testing distance0.50.84.0-0.10.81.50.6-2.00.40.70.30.21.20.70.90.1
Locomotor testing rearing0.40.63.6-0.80.01.4-0.1-1.9-0.5-0.1-0.5-0.70.9-0.1-0.0-0.5
Light reinforcement 12.03.611.90.71.63.41.5-3.41.21.30.80.53.31.21.2-0.2
Light reinforcement 20.91.22.70.91.11.61.2-1.21.11.10.90.91.31.00.9-0.6
Reaction time number correct3.34.87.52.52.41.12.6-0.22.62.42.72.71.32.52.51.0
Reaction time mean minus median0.81.02.4-0.5-1.1-1.5-1.21.4-0.8-1.1-0.9-0.6-1.1-0.7-0.8-0.3
Reaction time mean minus median AUC0.50.61.6-0.1-1.0-1.1-1.01.3-0.4-1.0-0.8-0.3-0.7-0.4-0.7-0.3
Reaction time num false alarms1.11.52.51.01.40.91.4-0.51.41.41.41.41.21.11.6-0.1
Reaction time num false alarms AUC1.72.33.91.21.81.31.7-0.91.61.81.61.61.61.62.00.6
Reaction time trials correct on left3.34.87.52.52.41.12.6-0.22.62.42.72.71.32.52.51.0
Reaction time trials on left3.24.57.42.52.31.02.5-0.02.62.32.62.71.22.42.40.9
Reaction time mean4.05.69.0-1.7-2.9-1.9-3.01.7-2.2-3.0-2.9-2.2-1.9-2.4-2.7-1.4
Reaction time mean AUC3.74.98.1-1.5-2.7-1.9-2.81.7-2.0-2.8-2.7-2.1-1.7-2.2-2.5-1.2
Median of all reaction times4.66.210.1-1.8-3.1-1.9-3.21.5-2.4-3.2-3.1-2.4-1.8-2.6-2.9-1.4
Reaction time omissions1.52.15.4-0.1-1.8-1.7-1.72.3-0.7-1.8-1.6-0.6-1.3-1.1-1.6-0.4
Reaction time false alarm rate0.10.20.8-0.00.40.70.3-0.70.20.30.10.10.90.20.5-0.0
Reaction time premature initiation rate0.81.14.1-0.41.01.40.8-2.00.10.90.4-0.21.20.70.81.8
Reaction time premature initiations2.43.44.80.92.22.02.1-1.91.52.01.81.31.71.92.02.1
Std. dev. reaction times1.72.34.2-0.5-1.9-1.7-1.82.0-1.1-1.8-1.6-0.9-1.6-1.3-1.6-1.1
Reaction time trials completed3.24.57.42.52.31.02.5-0.02.62.32.62.71.22.42.40.9
Reaction time trials AUC3.44.88.22.72.31.12.50.12.72.42.62.91.32.52.40.8
Social response proportion0.20.20.5-0.5-0.50.1-0.4-0.1-0.6-0.5-0.7-0.6-0.6-0.3-0.6-0.2
Social responses0.20.31.90.7-0.01.40.1-0.40.6-0.1-0.20.10.70.2-0.2-0.7
Social time2.22.89.3-0.3-1.4-2.8-1.33.1-0.9-1.1-0.7-0.5-3.0-1.1-1.2-1.1
Conditioned locomotion0.91.04.2-0.7-0.6-2.0-0.71.6-0.7-0.4-0.2-0.2-2.0-0.6-0.20.1
Cocaine response after cond. corrected2.32.64.71.11.90.01.90.41.42.12.21.80.21.82.01.9
Cocaine response after cond. not corrected3.53.96.31.62.30.92.3-0.11.92.42.42.00.92.42.22.5
Cocaine response before conditioning0.40.41.80.70.31.30.3-0.70.60.10.10.11.00.60.01.0
Saline control response0.20.30.90.90.30.60.30.30.70.20.30.50.70.50.20.5
Condit. Reinf. active minus inactive responses0.81.04.42.10.21.10.50.41.60.00.31.11.60.60.1-0.6
Condit. Reinf. active-inactive response ratio0.30.31.51.2-0.10.50.10.40.8-0.2-0.00.50.90.2-0.2-0.6
Condit. Reinf. active responses0.30.52.31.0-0.31.2-0.1-0.30.6-0.5-0.40.11.5-0.0-0.4-0.6
Condit. Reinf. inactive responses0.10.10.3-0.4-0.40.4-0.4-0.3-0.4-0.4-0.5-0.50.2-0.3-0.4-0.2
Condit. Reinf. lever presses1.01.42.6-1.0-1.20.5-1.3-1.1-1.0-1.4-1.6-1.50.8-1.3-1.2-0.9
Condit. Reinf. lever reinforcers received0.40.62.91.1-0.21.3-0.1-0.40.7-0.5-0.40.11.7-0.1-0.3-1.0
Pavlov. Cond. lever latency0.71.02.00.70.9-0.51.01.00.71.21.31.1-0.61.10.91.4
Pavlov. Cond. magazine entry latency0.40.42.0-0.30.31.20.2-1.40.10.2-0.1-0.11.00.10.4-0.7
Pavlov. Cond. change in total contacts1.31.83.3-1.0-1.21.0-1.3-1.5-1.0-1.6-1.8-1.60.8-1.5-1.3-1.6
Pavlov. Cond. index score0.50.72.2-0.4-0.51.0-0.6-1.2-0.4-0.7-0.9-0.71.0-0.7-0.5-1.5
Pavlov. Cond. latency score0.50.71.8-0.6-0.50.9-0.6-1.2-0.5-0.7-0.9-0.80.8-0.8-0.5-1.3
Pavlov. Cond. lever contacts0.71.01.6-0.8-0.80.6-1.0-1.3-0.8-1.1-1.2-1.20.8-1.0-0.8-1.2
Pavlov. Cond. magazine entry number0.50.73.1-0.3-0.3-1.4-0.31.2-0.5-0.2-0.0-0.2-1.2-0.1-0.41.7
Pavlov. Cond. intertrial magazine entries0.00.00.20.50.0-0.20.10.40.30.00.20.20.10.3-0.0-0.1
Pavlov. Cond. lever-magazine prob. diff.0.60.82.5-0.5-0.61.0-0.7-1.2-0.4-0.8-1.0-0.80.9-0.8-0.6-1.6
Pavlov. Cond. response bias0.60.82.6-0.6-0.70.8-0.7-1.2-0.5-0.9-1.1-0.90.9-0.9-0.6-1.6
Conditioned reinforcement - actives1.01.01.51.11.10.91.2-0.51.21.11.11.11.10.91.0-0.6
Conditioned reinforcement - inactives0.60.71.31.00.90.00.90.51.01.01.11.10.00.90.90.2
Conditioned locomotion0.91.02.00.81.20.11.30.31.01.41.41.2-0.31.21.20.4
Intermittent access intake day 1-15 change1.01.03.51.90.60.40.91.31.50.70.91.3-0.00.90.5-0.1
Intermittent access intake escalation1.41.44.32.10.90.61.21.11.71.01.21.60.21.20.8-0.3
Intermittent access intake escalation 20.70.71.21.00.7-0.50.81.10.90.91.11.1-0.50.70.7-0.2
Intermitt. access day 1 inactive lever presses0.10.10.60.5-0.10.80.0-0.20.4-0.1-0.20.00.70.2-0.1-0.2
Intermitt. access day 15 inactive lever presses2.42.74.21.31.91.11.7-0.91.71.81.81.51.42.01.91.7
Intermitt. access escalation Index0.20.20.40.40.40.30.5-0.20.50.40.40.30.60.50.4-0.2
Intermittent access day 1 total infusions0.40.51.5-1.1-0.4-1.2-0.60.2-0.9-0.3-0.3-0.7-1.0-0.6-0.3-0.1
Intermittent access day 15 total infusions0.60.61.71.10.5-0.50.61.30.90.70.91.0-0.60.50.5-0.5
Intermittent access terminal intake (last 3 days)0.20.20.70.00.2-0.90.20.70.10.30.50.2-0.70.00.3-0.5
Intermittent access total infusions0.40.41.5-0.1-0.4-1.2-0.41.2-0.3-0.3-0.0-0.1-1.1-0.4-0.3-0.6
Intermittent access day 1 locomotion0.10.10.5-0.3-0.4-0.5-0.40.5-0.4-0.3-0.2-0.3-0.7-0.3-0.3-0.1
Intermittent access day 15 total locomotion0.30.30.60.80.40.10.50.60.60.50.60.6-0.30.40.3-0.6
Intermittent access total locomotion0.00.10.30.00.2-0.10.20.20.00.30.30.0-0.60.30.10.1
Intermittent access standard deviation0.60.63.70.7-0.2-1.5-0.21.90.3-0.00.30.6-1.1-0.0-0.0-0.2
Cocaine induced anxiety4.34.98.01.92.70.82.7-0.32.32.82.82.30.82.72.72.1
Post-drug Anxiety0.10.10.30.20.4-0.10.40.00.30.40.40.3-0.20.40.40.6
Baseline Anxiety5.05.37.2-2.1-2.7-1.9-2.61.2-2.5-2.6-2.5-2.2-2.1-2.6-2.6-1.7
Lifetime Intake0.40.41.5-0.1-0.4-1.2-0.41.2-0.3-0.3-0.0-0.1-1.2-0.4-0.3-0.8
Incentive Sensitization - Responses0.90.91.50.71.1-0.20.9-0.10.91.01.11.00.71.11.21.2
Incentive Sensitization - Breakpoint1.01.01.60.81.2-0.11.0-0.11.01.11.21.10.91.21.31.2
Progressive ratio test 1 active lever presses0.20.21.1-0.20.1-0.5-0.10.5-0.10.10.2-0.0-0.60.10.11.0
Progressive ratio test 1 breakpoint0.20.20.6-0.5-0.2-0.6-0.30.3-0.4-0.2-0.2-0.3-0.7-0.2-0.20.8
Progressive ratio test 1 inactive lever presses0.40.40.6-0.3-0.7-0.8-0.80.7-0.5-0.7-0.5-0.6-0.7-0.7-0.6-0.3
Progressive ratio test 2 active lever presses0.40.40.80.50.7-0.70.50.50.60.70.90.8-0.10.70.80.9
Progressive ratio test 2 breakpoint0.30.30.60.40.6-0.40.50.30.50.60.70.60.10.50.70.8
Progressive ratio test 2 inactive lever presses0.70.81.70.70.9-0.90.80.80.81.11.31.1-0.30.91.10.7
Total sessions with >9 infusions0.30.30.8-0.6-0.40.6-0.4-0.5-0.6-0.5-0.6-0.9-0.1-0.6-0.6-0.4
Short access day 1 total inactive lever presses0.91.01.7-1.0-1.1-0.7-1.10.1-1.1-1.1-1.1-0.9-0.4-1.2-1.0-1.3
Short access day 10 total inactive lever presses2.02.23.31.51.61.11.7-0.41.71.71.71.81.11.81.60.8
Short access day 1 total infusions0.60.61.1-1.1-0.6-0.5-0.8-0.3-1.0-0.7-0.7-1.0-0.3-0.9-0.6-1.1
Short access day 10 total infusions1.01.11.5-1.0-1.2-0.8-1.20.6-1.2-1.2-1.1-1.1-1.1-1.2-1.2-0.7
Short access total infusions0.60.71.0-0.7-0.8-1.0-0.90.7-0.8-0.8-0.7-0.8-1.0-0.9-0.8-0.7
Short access day 1 locomotion0.20.20.9-0.60.00.7-0.1-1.0-0.4-0.1-0.2-0.70.5-0.2-0.10.0
Short access day 10 total locomotion1.11.22.9-1.7-0.90.2-1.0-1.3-1.5-1.0-1.3-1.70.2-1.1-1.0-0.3
Short access total locomotion1.31.42.6-1.3-1.10.3-1.1-0.7-1.3-1.3-1.4-1.60.0-1.3-1.3-1.2
Compulsive drug intake0.40.41.6-0.4-0.10.6-0.0-1.2-0.3-0.1-0.3-0.30.9-0.4-0.2-1.3
One hour access (0.3 mA shock)0.40.41.40.40.70.50.8-0.40.60.80.80.50.30.40.6-1.2
One hour access (shock baseline)0.10.10.30.30.30.00.30.40.30.40.50.3-0.40.20.2-0.5
Number of responses in last shaping day0.80.82.0-1.2-0.60.7-0.8-1.4-1.0-0.8-1.1-1.40.5-0.7-0.70.5
Context. condit. distance diff. score3.13.85.51.22.31.62.1-1.71.82.11.91.72.12.12.31.9
Locomotion velocity, session 11.01.02.3-0.6-1.3-0.3-1.20.5-1.0-1.3-1.2-1.0-0.6-1.1-1.5-0.6
Locomotion distance, session 11.11.43.11.70.90.41.11.11.51.11.31.80.11.51.00.7
Locomotion velocity, session 20.10.20.40.60.3-0.30.30.60.50.30.60.60.10.30.3-0.2
Locomotion distance, session 20.30.52.50.80.1-0.70.31.60.50.30.60.9-0.90.40.2-0.2
Locomotion velocity, session 30.40.41.7-1.10.0-1.3-0.10.2-0.80.20.2-0.3-1.2-0.20.20.4
Locomotion distance, session 30.70.72.4-1.1-0.6-1.6-0.60.7-1.1-0.4-0.3-0.5-1.5-0.7-0.50.1
Stereotopy head waving bouts, day 30.91.13.2-1.7-0.30.6-0.7-1.8-1.2-0.6-1.0-1.50.4-0.9-0.31.0
Stereotopy head waving duration, day 30.40.41.5-1.2-0.10.3-0.3-1.2-0.8-0.3-0.4-1.00.1-0.5-0.00.6
Locomotion velocity, session 71.21.43.30.31.50.01.3-0.20.81.51.41.10.31.21.61.8
Locomotion distance, session 71.21.52.51.51.30.91.40.31.61.31.41.50.91.41.30.7
Stereotopy head waving bouts, day 70.70.83.1-1.50.00.4-0.4-1.8-1.0-0.2-0.5-1.10.3-0.5-0.01.4
Stereotopy head waving duration, day 70.81.05.4-1.50.31.0-0.1-2.3-0.90.0-0.3-1.00.7-0.20.21.2
Locomotion velocity, session 81.82.14.71.11.42.21.4-1.41.41.21.01.12.11.41.31.2
Locomotion distance, session 82.74.05.71.72.31.22.2-0.52.12.32.32.21.32.32.42.1
Degree of sensitization distance1.71.73.31.81.21.61.3-0.21.81.01.01.21.81.31.10.2
Degree of sensitization stereotypy0.40.52.3-0.80.40.50.1-1.5-0.40.20.0-0.50.50.00.31.3
Condit. Reinf. active minus inactive responses0.60.62.70.00.71.00.7-1.60.40.60.40.31.00.40.8-0.8
Condit. Reinf. active-inactive response ratio0.40.42.6-0.7-0.2-0.2-0.3-0.9-0.5-0.3-0.4-0.50.1-0.6-0.1-1.6
Condit. Reinf. active responses0.70.81.30.70.81.10.9-1.00.90.80.70.91.00.80.9-1.0
Condit. Reinf. inactive responses1.41.73.71.91.01.51.30.11.81.01.11.71.31.41.0-0.2
Incentive salience index mean0.60.82.10.40.91.00.9-1.50.70.80.60.61.10.80.9-0.8
Condit. Reinf. lever presses0.10.20.70.1-0.00.50.1-0.70.00.0-0.10.10.60.2-0.1-0.8
Time in familiar zone, hab. session 12.92.84.0-1.1-1.9-1.5-1.91.4-1.5-1.8-1.6-1.3-1.8-2.0-1.7-1.9
Time in novel zone, hab. session 12.62.53.50.81.91.41.8-1.61.31.71.51.11.81.91.61.8
Total zone transitions, hab. session 10.71.04.50.41.10.31.0-0.00.71.11.10.90.01.11.22.1
Total locomotion distance, hab. session 11.62.36.61.01.6-0.31.50.91.31.71.91.6-0.51.61.92.6
Locomotion velocity, hab. session 11.42.04.91.11.5-0.41.41.01.31.61.71.6-0.51.41.72.2
Time in familiar zone, hab. session 20.70.81.6-0.8-0.80.7-0.9-0.8-0.8-1.0-1.2-1.30.3-1.0-0.9-0.3
Time in novel zone, hab. session 22.02.03.71.61.50.11.60.41.61.71.81.90.61.71.60.7
Total zone transitions, hab. session 21.11.42.91.01.21.31.1-0.71.21.11.01.01.31.31.11.7
Total locomotion distance, hab. session 21.82.44.11.71.61.01.60.11.81.61.61.71.01.81.62.0
Locomotion velocity, hab. session 21.42.03.41.41.50.71.50.11.51.51.51.60.81.71.51.9
Novel to familiar place preference ratio0.80.91.8-0.01.1-0.90.90.40.31.21.30.6-0.60.91.21.3
Novelty place preference0.60.61.6-0.40.8-1.00.60.2-0.00.91.00.2-0.70.60.91.3
Time in novel zone, NPP test0.60.71.8-0.11.0-0.70.80.20.21.11.10.4-0.50.81.11.4
Total zone transitions, NPP test1.11.52.91.21.11.71.0-0.91.30.90.81.01.61.31.01.7
Total locomotion distance, NPP test2.53.59.31.12.01.81.8-1.31.61.91.71.51.72.12.03.1
Locomotion velocity, NPP test2.02.98.10.71.91.31.7-1.21.31.91.71.31.31.91.92.8
Pavlov. Cond. lever latency0.50.61.3-0.10.9-0.70.70.40.31.01.00.6-0.80.51.11.0
Pavlov. Cond. magazine entry latency1.01.23.2-1.0-0.71.3-0.8-1.8-0.9-0.9-1.3-1.31.2-0.5-1.01.0
Pavlov. Cond. change in total contacts1.41.55.0-0.8-0.71.7-0.7-2.2-0.8-1.0-1.4-1.41.7-0.6-1.10.2
Pavlov. Cond. index score0.81.02.4-0.6-0.71.3-0.7-1.6-0.7-0.9-1.2-1.11.3-0.5-1.1-0.2
Pavlov. Cond. latency score0.81.01.8-0.6-0.90.9-0.9-1.2-0.8-1.1-1.3-1.21.0-0.6-1.3-0.3
Pavlov. Cond. lever contacts1.01.12.4-0.3-1.20.8-1.1-0.8-0.7-1.4-1.5-1.10.9-0.8-1.5-1.1
Pavlov. Cond. magazine entry number1.01.24.40.40.4-2.10.52.00.40.71.10.9-1.90.20.7-0.5
Pavlov. Cond. intertrial magazine entries1.21.42.81.71.30.61.40.31.71.31.41.50.31.21.30.0
Pavlov. Cond. lever-magazine prob. diff.0.81.02.1-0.7-0.81.2-0.8-1.5-0.8-1.0-1.3-1.11.2-0.6-1.1-0.2
Pavlov. Cond. response bias1.01.34.7-0.2-0.32.2-0.3-2.1-0.2-0.6-1.0-0.82.1-0.1-0.70.3
Bone: apparent density0.91.52.7-1.1-1.40.2-1.5-0.6-1.3-1.5-1.7-1.50.3-1.4-1.5-0.9
Bone surface1.62.85.2-1.4-2.0-0.3-2.1-0.2-1.8-2.2-2.3-2.0-0.2-1.8-2.2-0.6
Bone volume1.72.95.1-2.0-1.8-0.1-2.0-0.9-2.0-2.0-2.2-2.3-0.1-1.8-2.0-0.2
Bone: connectivity density0.10.10.5-0.1-0.20.4-0.3-0.5-0.1-0.2-0.4-0.20.70.1-0.2-0.4
Bone: cortical apparent density3.84.97.0-1.1-2.5-2.6-2.42.5-1.7-2.4-2.1-1.4-2.5-2.2-2.2-2.6
Bone: cortical area0.71.12.2-1.4-1.0-1.2-1.00.3-1.5-0.9-0.8-1.2-1.3-0.9-1.20.0
Bone: cortical porosity0.70.81.80.40.91.30.9-1.30.60.80.60.41.40.80.80.0
Bone: cortical porosity0.30.31.30.00.41.00.4-1.20.20.30.10.01.10.30.3-0.1
Bone: cortical thickness0.40.71.30.40.7-0.80.90.90.51.01.11.1-0.81.00.80.3
Bone: cortical thickness2.63.16.01.91.5-1.11.72.21.81.92.32.4-1.01.71.80.3
Bone: cortical tissue density3.84.97.0-1.1-2.5-2.5-2.42.5-1.7-2.4-2.1-1.4-2.4-2.2-2.2-2.6
Bone: elastic displacement0.70.71.31.00.7-0.00.91.11.01.01.21.2-0.40.90.80.0
Bone: elastic work2.22.84.41.61.91.42.0-0.31.92.02.01.91.12.11.90.7
Bone: endosteal estimation2.86.011.0-2.8-2.6-1.3-2.8-0.6-3.0-2.8-2.9-3.3-1.1-2.9-2.9-0.5
Bone: endosteal perimeter2.24.57.6-2.3-2.3-1.1-2.4-0.5-2.6-2.4-2.4-2.8-1.0-2.4-2.6-0.3
Bone: final force0.81.42.70.11.50.91.4-1.60.71.31.20.61.11.31.41.2
Bone: final moment0.50.82.5-0.01.00.91.0-1.60.40.90.70.31.10.81.00.9
Bone: marrow area3.06.511.8-2.9-2.7-1.3-2.9-0.7-3.1-2.9-3.0-3.4-1.1-3.0-3.0-0.5
Bone: maximum diameter2.64.77.3-2.2-2.4-1.9-2.50.6-2.6-2.4-2.3-2.5-1.9-2.4-2.7-0.3
Bone: maximum force0.40.73.1-1.10.70.10.4-1.4-0.60.70.5-0.30.00.40.61.7
Bone: maximum moment0.30.51.8-1.30.2-0.0-0.0-1.3-0.90.2-0.0-0.7-0.1-0.00.11.3
Bone: minimum diameter4.07.312.5-3.3-2.8-1.7-2.9-0.3-3.5-2.9-3.0-3.5-1.6-3.1-3.1-1.0
Bone: periosteal estimation2.24.47.5-2.5-2.2-1.5-2.3-0.2-2.7-2.3-2.3-2.7-1.4-2.3-2.5-0.1
Bone: periosteal perimeter2.33.87.1-2.2-2.1-0.8-2.2-0.8-2.5-2.2-2.3-2.7-0.7-2.1-2.5-0.2
Bone: post-yield work0.81.14.1-1.4-0.6-1.2-0.90.2-1.3-0.6-0.6-1.0-1.2-0.6-0.62.0
Bone: stiffness0.60.93.3-1.8-0.4-1.2-0.7-0.5-1.5-0.4-0.5-1.1-1.1-0.7-0.40.9
Bone: tissue strength1.41.32.61.41.01.61.2-0.31.40.90.81.21.51.30.90.5
Bone: trabecular number1.42.13.4-0.9-1.8-1.0-1.70.7-1.3-1.7-1.7-1.3-0.9-1.6-1.8-1.8
Bone: trabecular spacing1.62.14.10.81.90.81.9-0.61.22.02.01.30.41.71.80.8
Bone: trabecular thickness1.11.32.4-1.4-1.10.1-1.3-0.7-1.3-1.3-1.5-1.50.3-1.4-1.20.4
Bone: trabecular tissue density3.95.58.6-2.5-2.6-0.9-2.7-0.0-2.7-2.7-2.9-2.8-1.3-2.9-2.7-1.3
Breakpoint value in progressive ratio session1.31.47.9-0.90.61.90.3-2.8-0.30.3-0.4-0.61.90.20.41.2
Distance traveled before self-admin0.60.62.40.60.80.80.8-0.00.70.80.70.70.40.80.71.6
Distance traveled after self-admin0.20.21.1-0.70.10.3-0.1-1.0-0.40.0-0.0-0.60.3-0.20.00.5
Delta time in closed arm before/after self-admin0.70.62.1-0.4-0.9-0.9-0.80.7-0.7-0.8-0.6-0.4-0.6-0.9-0.8-1.5
Delta time in open arm before/after self-admin0.80.83.40.60.41.80.4-1.30.60.1-0.2-0.01.50.80.20.8
Diff in mean of infusions in LGA sessions0.40.41.80.1-0.30.9-0.4-1.00.1-0.6-0.8-0.31.3-0.2-0.30.1
Extinction: sum of active levers before priming1.11.15.2-1.8-0.11.2-0.3-2.3-1.2-0.3-0.7-1.40.4-0.5-0.30.5
Active lever presses in extinction session 61.41.34.8-1.2-0.61.4-0.7-2.2-1.0-0.9-1.3-1.51.1-0.8-0.8-0.1
Delta distance traveled before/after self-admin1.21.33.0-1.0-1.1-0.0-1.1-0.9-1.1-1.3-1.3-1.40.2-1.3-1.1-1.7
Delta ambulatory time before/after self-admin1.11.22.2-1.1-1.1-0.2-1.2-0.8-1.1-1.3-1.3-1.40.2-1.2-1.2-1.5
Time in closed arm before self-admin0.50.51.30.30.70.90.6-1.00.50.60.40.31.20.70.71.0
Time in closed arm after self-admin0.20.20.7-0.4-0.5-0.6-0.40.2-0.4-0.4-0.3-0.2-0.0-0.6-0.3-0.8
Time in open arm before self-admin0.40.42.7-0.7-0.2-1.6-0.30.7-0.6-0.00.10.0-0.9-0.40.1-0.2
Time in open arm after self-admin0.70.81.7-0.8-0.80.3-1.0-0.9-0.8-1.1-1.3-1.30.4-0.6-0.90.2
Sum of active levers in priming session hrs 5-61.81.810.1-1.50.52.20.2-3.2-0.80.2-0.4-1.11.40.10.21.3
Time to tail flick, vehicle, before self-admin1.41.45.4-0.0-0.9-1.9-0.71.9-0.4-0.7-0.20.0-1.6-0.9-0.7-2.3
Time to tail flick, vehicle, after self-admin2.83.05.62.41.81.21.7-0.22.41.61.82.12.01.51.80.5
Time to tail flick, test, before self-admin2.92.94.61.52.00.71.90.31.72.12.11.9-0.12.02.01.8
Time to tail flick, test, after self-admin1.11.25.60.90.1-2.00.12.40.60.40.71.1-1.50.30.5-0.0
Delta time to tail flick, vehicle, before/after SA4.74.56.72.42.22.52.1-1.12.51.91.82.02.62.12.02.1
Delta time to tail flick, test, before/after SA0.90.83.5-0.1-0.7-1.9-0.81.5-0.3-0.7-0.3-0.1-1.0-0.8-0.5-1.0
Ambulatory time before self-admin0.30.30.90.50.50.90.5-0.10.60.50.40.40.40.50.40.9
Ambulatory time after self-admin0.50.63.0-0.30.41.30.3-1.70.00.20.0-0.41.30.20.30.7
Total heroin consumption1.82.210.6-1.50.71.70.2-3.3-0.70.3-0.2-0.91.80.30.62.6
Area under the delay curve0.10.10.30.0-0.10.5-0.1-0.5-0.0-0.2-0.3-0.30.40.2-0.20.4
Delay disc. indifference point, 0s delay0.50.52.21.50.30.90.40.31.20.20.20.81.00.50.2-0.5
Delay disc. indifference point, 16s delay0.80.81.3-1.2-0.9-0.9-1.10.1-1.2-0.9-1.0-1.1-0.6-0.6-0.80.9
Delay disc. indifference point, 2s delay0.91.12.51.01.01.61.0-1.11.10.80.70.71.51.10.80.4
Delay disc. indifference point, 24s delay0.20.20.5-0.2-0.4-0.7-0.50.6-0.3-0.4-0.3-0.2-0.4-0.2-0.3-0.3
Delay disc. indifference point, 4s delay0.40.41.1-0.4-0.7-0.6-0.60.6-0.6-0.6-0.5-0.5-1.0-0.6-0.7-0.6
Delay disc. indifference point, 8s delay0.40.41.70.00.11.3-0.0-1.20.1-0.1-0.4-0.41.10.3-0.10.4
Delay discount exponential model param0.10.10.30.00.0-0.50.10.50.00.10.20.3-0.4-0.20.1-0.4
Delay discount hyperbolic model param0.10.10.3-0.1-0.1-0.6-0.00.4-0.1-0.00.10.1-0.3-0.30.0-0.3
Fecal boli incidents, locomotor time 11.81.93.51.01.70.81.6-0.31.41.71.61.30.81.51.71.9
Change in fecal boli incidents, locomotor task2.32.26.2-1.3-1.3-2.5-1.31.7-1.5-1.1-0.8-1.0-2.4-1.4-1.0-0.3
Time >=10cm from walls, locomotor time 12.42.45.30.61.81.31.7-1.61.11.71.51.01.31.61.82.3
Bouts of movement, locomotor time 12.73.05.4-1.9-1.9-0.4-1.9-0.4-2.0-2.0-2.1-2.3-0.9-2.1-2.0-0.8
Total resting periods, locomotor time 12.73.05.0-1.9-1.9-0.7-1.9-0.1-2.0-2.0-2.1-2.2-1.1-2.1-2.0-0.8
Rest time, locomotor task time 10.91.01.8-0.9-1.1-1.1-1.10.9-1.0-1.0-0.9-0.9-1.3-1.0-1.00.1
Distance moved, locomotor task time 10.50.50.90.70.70.70.7-0.60.70.70.70.80.90.60.7-0.8
Vertical activity count, locomotor time 12.22.23.51.71.70.61.70.01.81.71.81.91.11.71.70.7
Time >=10cm from walls, locomotor time 26.36.710.22.43.01.93.0-1.02.83.13.02.91.93.22.91.6
Bouts of movement, locomotor time 22.72.94.8-0.9-2.1-0.9-2.01.1-1.4-2.1-2.0-1.7-1.3-1.9-2.2-1.7
Total resting periods, locomotor time 23.43.65.9-1.0-2.4-1.2-2.21.4-1.6-2.4-2.2-1.8-1.6-2.1-2.4-1.8
Rest time, locomotor task time 21.01.15.70.5-0.8-1.6-0.52.4-0.0-0.5-0.20.2-1.7-0.6-0.6-1.1
Distance moved, locomotor task time 20.91.03.40.30.91.70.7-1.80.60.70.50.51.70.80.70.1
Vertical activity count, locomotor time 21.21.31.91.01.21.11.1-0.71.11.21.11.11.31.41.11.1
Weight adjusted by age1.11.34.2-1.4-0.61.0-0.8-2.0-1.1-0.9-1.2-1.41.2-1.0-0.80.3
Seeking ratio, delayed vs. immediate footshock0.20.21.00.3-0.0-0.80.11.00.20.10.30.4-0.60.10.2-0.1
Locomotion in novel chamber0.30.41.4-0.1-0.4-1.1-0.31.2-0.3-0.2-0.00.1-1.2-0.3-0.3-0.7
Locomotion in novel chamber post-restriction0.20.21.6-0.60.30.40.3-1.3-0.30.40.2-0.10.50.20.30.1
Progressive ratio0.10.20.4-0.6-0.2-0.2-0.4-0.6-0.5-0.3-0.4-0.50.5-0.4-0.20.3
Food seeking constrained by brief footshock0.40.51.80.70.60.60.5-0.30.70.60.60.70.80.90.71.3
Seeking ratio, punishment vs. effort0.40.50.80.80.70.80.8-0.00.80.70.70.70.10.90.60.9
Run reversals in cocaine runway, females0.80.81.6-0.7-0.90.3-0.8-0.4-0.8-1.0-1.0-1.10.1-1.1-1.0-1.3
Run reversals in cocaine runway, males1.11.04.6-0.1-1.2-0.5-1.00.6-0.5-1.2-1.1-0.6-0.0-1.1-1.1-2.2
Latency to leave start box in cocaine runway1.01.12.3-0.1-1.5-0.3-1.31.0-0.7-1.5-1.5-1.0-0.7-1.0-1.5-0.5
Latency to leave start box in cocaine runway, F0.91.02.0-0.6-1.3-0.2-1.20.4-0.9-1.4-1.4-1.1-0.4-1.0-1.3-0.4
Latency to leave start box in cocaine runway, M0.90.81.4-0.3-1.1-0.8-1.01.2-0.6-1.1-1.1-0.7-1.1-0.8-1.1-0.1
Cd content in liver1.61.83.51.61.40.41.50.31.71.51.61.90.51.51.6-0.0
Co content in liver0.30.30.6-0.8-0.4-0.4-0.6-0.8-0.7-0.6-0.6-0.80.1-0.6-0.5-0.3
Cu content in liver1.82.13.81.91.31.81.6-0.51.91.31.21.62.01.41.30.0
Fe content in liver1.92.23.4-1.2-1.8-1.1-1.80.7-1.5-1.8-1.8-1.5-1.0-1.8-1.8-1.1
K content in liver0.50.52.6-0.4-0.8-0.2-0.60.3-0.6-0.7-0.6-0.5-0.3-0.9-0.9-1.6
Mg content in liver1.92.08.1-0.5-1.7-0.5-1.40.7-0.9-1.6-1.5-0.9-0.5-1.5-1.7-2.9
Mn content in liver2.22.57.3-0.9-1.6-1.6-1.50.9-1.4-1.5-1.2-1.2-1.6-1.8-1.6-2.7
Na content in liver0.20.20.5-0.0-0.40.7-0.3-0.2-0.2-0.4-0.5-0.30.7-0.4-0.50.2
Rb content in liver1.31.74.60.1-1.5-1.3-1.31.6-0.5-1.4-1.0-0.5-1.2-1.5-1.4-2.2
Se content in liver0.20.20.60.80.3-0.20.40.50.70.30.50.70.20.40.40.1
Sr content in liver0.60.61.20.41.00.10.9-0.00.71.01.00.90.10.71.10.7
Zn content in liver0.80.98.80.1-0.60.5-0.3-0.2-0.0-0.6-0.5-0.20.6-0.6-0.6-3.0