Hub : Genes

Thra

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000012340 0.06 0.04 9.2e-08 0.06 0.04 0.06 0.06 2.1e-07 2.5e-05 9.0e-07 2.4e-07
2 Adipose alternative polyA ENSRNOT00000104844 0.04 0.03 1.1e-05 0.03 0.03 0.03 0.03 2.9e-04 5.0e-04 1.4e-04 2.1e-04
3 Adipose alternative polyA ENSRNOT00000012340 0.05 0.03 2.6e-06 0.04 0.04 0.04 0.04 1.8e-05 7.2e-05 6.0e-05 3.9e-05
4 Adipose alternative polyA ENSRNOT00000104844 0.04 0.03 1.9e-06 0.03 0.03 0.04 0.04 2.2e-04 9.3e-05 5.0e-05 4.2e-05
5 Adipose isoform ratio ENSRNOT00000012340 0.04 0.04 2.4e-04 0.03 0.01 0.02 0.02 1.6e-04 1.9e-02 2.2e-03 1.9e-03
6 Adipose mRNA stability ENSRNOG00000009066 0.02 0.02 5.5e-03 0.03 0.02 0.03 0.03 5.4e-04 6.6e-03 4.5e-04 7.2e-04
7 BLA gene expression ENSRNOG00000009066 0.08 0.06 8.8e-03 0.02 -0 -0 0.01 2.5e-02 5.9e-01 8.0e-01 8.8e-02
8 Brain gene expression ENSRNOG00000009066 0.11 0.06 5.7e-08 0.07 0.08 0.09 0.09 6.6e-07 3.7e-08 2.1e-08 2.4e-08
9 PL isoform ratio ENSRNOT00000104844 0.05 0.04 1.3e-03 0 0.02 0.01 0.01 1.3e-01 2.0e-02 4.3e-02 4.0e-02
10 PL intron excision ratio chr10:83724852:83728568 0.08 0.06 4.3e-03 0.01 0.03 0.01 0.01 4.7e-02 4.1e-03 5.4e-02 3.4e-02
11 PL intron excision ratio chr10:83724852:83728685 0.08 0.06 1.9e-03 0.01 0.03 0.02 0.01 4.1e-02 3.4e-03 1.3e-02 3.5e-02
12 PL mRNA stability ENSRNOG00000009066 0.05 0.04 3.9e-03 0.03 0.02 0.02 0.03 1.3e-03 5.7e-03 8.3e-03 3.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.86.012.12.8-2.92.6-2.82.12.5-2.4-1.52.9-0.81.13.5
BMI without tail0.10.20.50.7-0.70.5-0.6-0.10.3-0.2-0.40.5-0.10.20.5
Body weight4.117.326.34.5-4.54.6-4.94.24.2-4.8-2.84.7-1.62.15.1
Epididymis fat weight0.10.20.50.2-0.40.3-0.30.70.1-0.60.30.20.5-0.40.7
Glucose0.10.10.6-0.10.2-0.30.2-0.00.10.70.5-0.00.1-0.10.2
Heart weight3.14.46.12.2-2.21.9-2.22.22.5-1.9-1.82.4-1.81.92.1
Left kidney weight0.92.64.12.0-1.41.6-1.81.31.4-1.9-1.91.6-1.41.51.0
Right kidney weight0.10.30.70.6-0.30.5-0.60.50.5-0.9-0.20.50.4-0.30.6
Tail length0.20.50.90.7-0.70.8-0.90.90.4-0.8-0.90.5-0.70.70.2
Length with tail2.17.812.12.8-2.73.1-3.23.32.6-3.5-2.52.9-1.82.02.6
Length without tail2.76.010.52.4-2.42.7-2.82.92.4-3.2-1.62.7-0.91.12.9
Liver weight, left0.00.10.1-0.30.3-0.10.20.1-0.30.20.2-0.30.2-0.2-0.2
Liver weight, right0.60.91.8-0.91.4-1.11.1-0.9-0.80.90.8-1.00.8-0.9-0.9
Parametrial fat weight2.34.66.0-2.32.4-1.82.1-2.2-2.01.52.4-2.12.5-2.5-1.5
Retroperitoneal fat weight0.00.10.30.20.10.0-0.1-0.10.6-0.30.20.30.1-0.00.5
Intraocular pressure2.73.86.62.2-2.61.8-2.11.82.0-1.8-1.92.1-1.51.61.7
Extensor digitorum longus weight9.236.946.36.4-6.86.3-6.86.36.0-6.2-6.06.3-4.85.15.4
Soleus weight0.10.41.40.3-0.60.2-0.30.1-0.0-0.00.70.31.2-1.11.2
Tibialis anterior weight1.34.66.92.5-2.62.3-2.52.22.1-2.3-1.62.4-1.01.22.4
Tibia length1.44.08.92.2-2.22.1-2.32.12.1-2.2-0.92.4-0.30.63.0
Number of licking bursts0.40.51.5-0.50.5-0.30.4-0.2-0.80.21.2-0.41.2-1.20.3
Food consumed during 24 hour testing period0.60.71.40.8-0.90.8-0.90.70.9-1.2-0.61.0-0.50.61.1
Times rat made contact with spout1.11.32.2-1.21.1-1.11.2-1.4-1.11.01.5-1.01.2-1.2-0.7
Mean time between licks in bursts1.01.42.91.4-1.31.2-1.30.91.1-1.7-0.81.3-0.50.61.4
Mean num. licks in bursts0.20.20.5-0.40.3-0.50.5-0.7-0.10.5-0.1-0.3-0.30.3-0.7
Std. dev. time between licks in bursts0.10.10.20.1-0.10.2-0.2-0.0-0.0-0.40.10.10.4-0.40.5
Water consumed over 24 hours0.10.10.3-0.1-0.00.2-0.10.10.3-0.50.00.4-0.00.10.5
Indifference point 0 sec1.52.44.2-1.61.5-1.71.8-1.9-1.51.91.0-1.80.4-0.5-2.0
Indifference point AUC0.10.10.30.2-0.20.5-0.40.60.40.1-0.10.2-0.00.00.3
Indifference point function ln k0.10.20.60.3-0.10.0-0.1-0.2-0.0-0.2-0.70.1-0.80.7-0.3
Indifference point function log k0.10.20.60.3-0.10.0-0.1-0.2-0.0-0.2-0.70.1-0.80.7-0.3
Delay discounting total patch changes 0 sec1.01.73.0-1.41.2-1.41.5-1.6-1.21.70.7-1.50.2-0.4-1.7
Delay discounting total patch changes 12 sec5.26.98.9-2.82.6-2.52.8-2.6-2.43.02.9-2.82.3-2.4-2.4
Delay discounting total patch changes 18 sec0.40.50.8-0.80.7-0.70.8-0.6-0.80.90.7-0.90.4-0.5-0.9
Delay discounting total patch changes 24 sec1.11.42.4-1.51.5-1.01.2-0.8-1.21.50.8-1.30.8-0.9-1.2
Delay discounting total patch changes 6 sec2.03.04.8-1.81.8-1.81.9-2.0-1.52.21.5-1.81.0-1.1-1.8
Delay discounting time to switch 0 sec0.10.20.3-0.30.2-0.40.4-0.4-0.40.40.5-0.40.5-0.5-0.4
Delay discounting water rate 0 sec0.10.10.2-0.40.4-0.40.4-0.4-0.30.30.2-0.30.0-0.0-0.2
Delay discounting water rate 12 sec0.10.10.50.1-0.10.3-0.30.7-0.3-0.7-0.30.0-0.30.3-0.1
Delay discounting water rate 18 sec0.70.91.4-1.01.2-0.60.8-0.7-1.20.71.1-0.91.1-1.1-0.6
Delay discounting water rate 24 sec0.91.21.8-1.11.3-1.31.3-1.4-1.00.91.1-1.00.7-0.8-0.9
Delay discounting water rate 6 sec1.82.73.7-1.81.9-1.71.9-1.6-1.81.61.5-1.71.3-1.3-1.4
Locomotor activity0.81.32.9-1.11.0-0.70.9-0.8-1.20.51.7-1.01.7-1.7-0.2
Locomotor testing distance2.13.54.4-2.01.8-1.82.0-2.0-2.11.62.1-2.01.7-1.8-1.4
Locomotor testing rearing5.79.012.2-3.13.3-3.43.5-3.5-3.13.12.3-3.31.5-1.8-3.4
Light reinforcement 13.25.87.3-2.52.6-2.52.7-2.7-2.32.52.3-2.51.9-2.0-2.2
Light reinforcement 20.81.01.8-0.90.9-1.01.1-1.0-0.51.31.3-0.71.3-1.3-0.3
Reaction time number correct0.50.81.90.6-0.70.8-0.81.40.9-1.1-0.11.0-0.40.51.1
Reaction time mean minus median0.50.61.80.9-1.30.9-0.90.80.6-0.8-0.80.6-0.50.50.6
Reaction time mean minus median AUC0.10.10.40.2-0.60.3-0.30.20.1-0.3-0.20.2-0.10.10.2
Reaction time num false alarms0.60.91.6-1.11.0-0.81.0-0.9-0.60.91.2-0.71.3-1.3-0.2
Reaction time num false alarms AUC0.50.71.7-0.90.7-0.60.8-0.7-0.60.71.2-0.61.3-1.3-0.0
Reaction time trials correct on left0.50.81.90.6-0.70.8-0.81.40.9-1.1-0.11.0-0.40.51.1
Reaction time trials on left0.50.71.80.6-0.70.8-0.81.40.9-1.1-0.11.0-0.40.51.1
Reaction time mean0.10.20.9-0.40.3-0.10.3-0.5-0.6-0.1-0.1-0.7-0.10.0-1.0
Reaction time mean AUC0.10.20.8-0.40.4-0.10.2-0.4-0.6-0.1-0.2-0.7-0.10.0-0.9
Median of all reaction times0.81.12.6-1.21.2-0.91.1-1.2-1.30.50.5-1.40.4-0.5-1.6
Reaction time omissions1.11.52.0-1.41.2-1.21.3-1.3-1.11.21.3-1.31.2-1.2-0.9
Reaction time false alarm rate0.91.21.8-1.11.0-1.01.1-1.3-1.01.21.1-1.11.3-1.3-0.6
Reaction time premature initiation rate0.60.81.4-0.91.2-0.40.6-0.2-1.00.31.2-1.01.1-1.1-0.7
Reaction time premature initiations0.20.20.7-0.30.50.3-0.10.7-0.2-0.60.8-0.10.6-0.50.1
Std. dev. reaction times0.10.10.40.3-0.60.4-0.40.2-0.0-0.4-0.2-0.0-0.00.0-0.1
Reaction time trials completed0.50.71.80.6-0.70.8-0.81.40.9-1.1-0.11.0-0.40.51.1
Reaction time trials AUC0.50.71.90.6-0.70.7-0.71.40.9-1.1-0.21.0-0.60.61.0
Social response proportion0.40.40.80.7-0.40.5-0.60.60.9-0.4-0.40.8-0.60.60.7
Social responses0.10.20.5-0.00.1-0.20.2-0.5-0.10.60.7-0.00.6-0.60.3
Social time0.30.31.3-0.2-0.20.2-0.1-0.10.1-0.20.80.21.2-1.00.9
Conditioned locomotion0.10.10.4-0.50.4-0.20.3-0.2-0.40.5-0.2-0.4-0.10.0-0.6
Cocaine response after cond. corrected1.01.12.2-0.90.9-0.80.9-0.7-1.01.11.5-0.71.5-1.50.1
Cocaine response after cond. not corrected1.11.22.4-1.00.9-0.91.0-0.7-1.01.31.6-0.81.5-1.60.1
Cocaine response before conditioning0.10.10.2-0.20.1-0.30.3-0.1-0.00.4-0.1-0.2-0.20.2-0.4
Saline control response0.20.30.80.5-0.60.4-0.50.70.5-0.40.00.60.1-0.10.9
Condit. Reinf. active minus inactive responses1.21.52.0-1.31.2-1.31.4-1.1-1.21.01.3-1.31.3-1.3-1.0
Condit. Reinf. active-inactive response ratio1.31.42.0-1.21.1-1.21.3-1.1-1.01.01.3-1.11.4-1.4-0.6
Condit. Reinf. active responses2.23.14.1-1.71.8-1.81.9-1.6-1.81.42.0-1.82.0-2.0-1.2
Condit. Reinf. inactive responses2.22.83.7-1.61.8-1.71.8-1.6-1.71.61.9-1.61.7-1.7-1.1
Condit. Reinf. lever presses0.10.20.3-0.40.5-0.40.4-0.4-0.60.10.4-0.50.2-0.2-0.5
Condit. Reinf. lever reinforcers received2.13.03.7-1.71.8-1.81.9-1.6-1.81.51.9-1.81.7-1.8-1.4
Pavlov. Cond. lever latency0.50.61.30.8-0.80.8-0.80.80.9-0.2-1.20.8-0.80.80.5
Pavlov. Cond. magazine entry latency0.10.10.4-0.0-0.20.4-0.30.50.2-0.50.30.30.1-0.10.6
Pavlov. Cond. change in total contacts0.60.81.3-0.80.9-1.11.1-1.0-0.90.70.9-1.00.3-0.4-1.1
Pavlov. Cond. index score0.20.30.9-0.50.4-0.50.5-0.5-0.50.10.9-0.40.6-0.6-0.0
Pavlov. Cond. latency score0.10.10.6-0.40.3-0.30.3-0.3-0.3-0.00.8-0.30.5-0.50.1
Pavlov. Cond. lever contacts0.91.32.8-1.11.1-1.11.1-1.2-1.20.71.7-1.11.3-1.3-0.5
Pavlov. Cond. magazine entry number0.00.10.30.3-0.10.0-0.1-0.00.10.1-0.50.1-0.30.3-0.2
Pavlov. Cond. intertrial magazine entries1.92.54.81.6-1.61.4-1.61.51.5-1.5-2.21.2-1.91.90.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.6-0.40.3-0.30.4-0.3-0.3-0.00.8-0.30.5-0.50.1
Pavlov. Cond. response bias1.31.83.4-1.41.4-1.31.4-1.3-1.40.91.8-1.31.4-1.4-0.7
Conditioned reinforcement - actives0.50.51.3-0.90.5-0.60.8-0.2-1.10.60.8-0.80.3-0.4-0.8
Conditioned reinforcement - inactives2.02.33.5-1.81.6-1.61.8-1.7-1.61.51.2-1.50.5-0.6-1.9
Conditioned locomotion0.40.41.0-0.70.2-0.40.50.2-1.00.70.9-0.80.7-0.7-0.5
Intermittent access intake day 1-15 change0.70.71.5-1.01.0-0.50.7-0.8-1.20.60.7-0.90.6-0.6-0.8
Intermittent access intake escalation0.70.71.6-1.01.1-0.50.7-0.8-1.30.60.8-0.90.7-0.7-0.8
Intermittent access intake escalation 20.10.10.2-0.40.30.10.1-0.3-0.40.00.3-0.20.4-0.4-0.1
Intermitt. access day 1 inactive lever presses2.93.15.0-1.82.2-1.71.9-2.2-1.51.81.6-1.71.4-1.5-1.5
Intermitt. access day 15 inactive lever presses4.34.75.9-2.32.3-2.22.4-2.4-2.42.42.0-2.41.3-1.5-2.2
Intermitt. access escalation Index2.01.83.81.5-1.11.4-1.61.01.4-1.9-1.21.5-0.70.81.3
Intermittent access day 1 total infusions0.20.30.5-0.50.5-0.60.6-0.2-0.40.50.7-0.50.4-0.4-0.4
Intermittent access day 15 total infusions0.80.91.8-1.11.3-0.91.0-0.8-1.20.80.9-0.90.4-0.5-1.0
Intermittent access terminal intake (last 3 days)1.01.11.8-1.21.3-1.01.1-1.0-1.10.91.0-1.00.7-0.7-1.0
Intermittent access total infusions0.30.40.8-0.80.9-0.60.7-0.4-0.70.40.7-0.60.3-0.3-0.6
Intermittent access day 1 locomotion0.20.20.5-0.40.2-0.70.70.0-0.60.70.4-0.4-0.0-0.0-0.4
Intermittent access day 15 total locomotion0.30.40.7-0.80.3-0.70.8-0.1-0.60.80.8-0.50.4-0.4-0.5
Intermittent access total locomotion0.70.81.4-1.00.6-1.01.1-0.5-1.21.00.8-1.00.3-0.4-1.0
Intermittent access standard deviation2.42.64.3-2.12.0-1.51.8-1.6-1.91.31.2-1.80.9-1.0-1.8
Cocaine induced anxiety1.51.83.31.5-1.31.5-1.61.01.5-1.7-0.61.40.3-0.11.8
Post-drug Anxiety0.20.20.50.5-0.30.4-0.50.30.5-0.5-0.00.50.2-0.10.7
Baseline Anxiety1.01.12.1-1.11.0-1.21.3-0.7-1.21.50.5-1.1-0.30.1-1.4
Lifetime Intake0.40.51.1-0.81.0-0.70.8-0.4-0.90.50.7-0.70.4-0.4-0.7
Incentive Sensitization - Responses1.41.42.1-1.40.9-1.21.4-1.1-1.31.31.2-1.30.7-0.8-1.3
Incentive Sensitization - Breakpoint1.31.41.9-1.40.8-1.21.4-1.1-1.31.31.2-1.20.7-0.8-1.2
Progressive ratio test 1 active lever presses0.50.51.0-0.70.9-1.00.9-0.8-0.80.70.5-0.70.2-0.3-0.6
Progressive ratio test 1 breakpoint0.40.40.8-0.60.9-0.90.9-0.7-0.70.70.5-0.60.2-0.2-0.6
Progressive ratio test 1 inactive lever presses1.81.93.1-1.41.7-1.41.5-1.8-1.51.40.9-1.50.7-0.7-1.5
Progressive ratio test 2 active lever presses1.31.42.0-1.31.2-1.31.4-1.1-1.41.11.1-1.30.5-0.6-1.3
Progressive ratio test 2 breakpoint0.91.01.6-1.11.1-1.11.2-0.9-1.30.90.9-1.10.4-0.5-1.1
Progressive ratio test 2 inactive lever presses0.70.81.2-1.11.0-0.91.1-0.8-0.91.00.9-0.90.4-0.5-0.9
Total sessions with >9 infusions0.70.81.8-1.01.3-0.80.9-1.1-1.10.90.3-0.8-0.0-0.1-0.9
Short access day 1 total inactive lever presses2.42.74.0-1.92.0-1.71.9-1.3-1.51.81.5-1.71.0-1.1-1.8
Short access day 10 total inactive lever presses0.00.10.2-0.20.30.5-0.20.10.2-0.3-0.00.10.3-0.2-0.0
Short access day 1 total infusions1.01.12.7-1.11.7-1.21.3-1.1-1.11.10.6-1.00.2-0.3-1.0
Short access day 10 total infusions0.50.51.0-0.70.7-0.80.8-0.6-0.80.61.0-0.70.7-0.7-0.5
Short access total infusions0.50.51.6-0.81.3-0.70.8-0.6-0.90.60.5-0.70.2-0.2-0.8
Short access day 1 locomotion4.04.26.3-2.12.2-2.12.3-2.5-2.22.21.7-2.11.2-1.3-2.1
Short access day 10 total locomotion1.21.32.0-1.10.6-1.41.4-1.1-1.31.31.1-1.20.9-0.9-1.1
Short access total locomotion0.50.50.9-0.80.8-0.90.9-0.7-0.90.80.3-0.7-0.10.1-0.9
Compulsive drug intake0.90.92.80.7-0.60.6-0.70.70.5-0.8-1.50.7-1.71.60.1
One hour access (0.3 mA shock)0.00.00.1-0.10.1-0.10.10.3-0.3-0.2-0.1-0.1-0.20.2-0.2
One hour access (shock baseline)0.50.61.1-0.80.8-0.80.8-0.5-0.70.71.0-0.70.9-0.9-0.5
Number of responses in last shaping day0.60.61.1-0.81.0-0.80.8-0.8-1.00.90.1-0.8-0.10.1-0.9
Context. condit. distance diff. score2.02.45.51.0-0.81.3-1.31.31.8-1.5-1.91.4-2.32.30.6
Locomotion velocity, session 10.30.40.90.6-0.70.6-0.70.80.7-0.4-0.40.70.10.00.9
Locomotion distance, session 11.72.24.91.4-1.71.7-1.71.81.6-1.2-0.81.7-0.10.32.2
Locomotion velocity, session 20.10.20.30.6-0.50.5-0.50.50.3-0.2-0.50.3-0.20.20.2
Locomotion distance, session 20.20.31.20.1-0.30.4-0.40.5-0.0-0.00.50.21.1-0.90.9
Locomotion velocity, session 30.00.10.3-0.10.3-0.20.2-0.1-0.20.1-0.1-0.3-0.10.1-0.5
Locomotion distance, session 30.20.20.40.4-0.50.5-0.50.60.4-0.6-0.30.4-0.20.20.5
Stereotopy head waving bouts, day 32.02.43.6-1.51.7-1.81.8-1.9-1.61.71.1-1.70.6-0.7-1.9
Stereotopy head waving duration, day 30.10.10.4-0.10.3-0.40.3-0.6-0.20.30.2-0.2-0.0-0.0-0.3
Locomotion velocity, session 71.01.02.11.0-1.21.1-1.21.40.9-1.0-0.61.1-0.10.21.4
Locomotion distance, session 70.50.61.10.7-1.00.8-0.81.10.8-0.3-0.70.8-0.50.60.8
Stereotopy head waving bouts, day 70.50.50.7-0.80.9-0.80.8-0.8-0.70.60.8-0.70.8-0.8-0.5
Stereotopy head waving duration, day 70.30.40.6-0.60.8-0.60.6-0.6-0.60.40.7-0.60.7-0.7-0.4
Locomotion velocity, session 87.48.910.82.9-3.03.1-3.33.13.2-3.1-2.93.2-2.42.62.8
Locomotion distance, session 81.11.62.31.1-1.11.4-1.41.51.5-1.4-1.01.4-0.80.91.4
Degree of sensitization distance1.31.31.71.2-1.21.1-1.21.21.3-0.7-1.31.3-1.21.20.9
Degree of sensitization stereotypy0.91.01.4-1.11.2-0.91.0-0.9-0.90.81.1-0.91.1-1.1-0.6
Condit. Reinf. active minus inactive responses0.70.82.2-0.91.0-0.80.9-0.7-1.01.10.4-1.20.2-0.3-1.5
Condit. Reinf. active-inactive response ratio0.80.93.2-0.91.0-0.91.0-0.8-1.01.00.1-1.2-0.20.1-1.8
Condit. Reinf. active responses0.70.92.0-1.01.1-0.91.0-0.7-1.01.10.6-1.20.3-0.4-1.4
Condit. Reinf. inactive responses0.20.20.5-0.50.5-0.20.4-0.1-0.40.40.7-0.30.6-0.7-0.0
Incentive salience index mean1.72.13.3-1.41.5-1.41.5-1.4-1.51.81.1-1.70.8-0.9-1.8
Condit. Reinf. lever presses0.91.22.5-1.00.9-1.11.1-1.0-1.01.61.1-1.20.9-1.0-1.1
Time in familiar zone, hab. session 10.70.71.9-0.50.5-0.70.7-0.8-0.40.91.3-0.31.4-1.30.4
Time in novel zone, hab. session 10.50.51.9-0.60.8-0.60.7-0.5-0.60.5-0.3-0.8-0.70.5-1.4
Total zone transitions, hab. session 11.62.23.11.3-1.41.5-1.61.51.8-1.4-1.71.6-1.31.41.2
Total locomotion distance, hab. session 10.00.10.2-0.30.3-0.10.20.10.30.0-0.30.1-0.50.4-0.2
Locomotion velocity, hab. session 10.20.30.60.4-0.40.5-0.50.60.7-0.7-0.70.5-0.60.70.3
Time in familiar zone, hab. session 20.80.81.5-0.91.0-0.80.9-0.9-0.71.11.2-0.71.0-1.0-0.4
Time in novel zone, hab. session 20.10.10.5-0.20.3-0.40.4-0.3-0.50.1-0.1-0.5-0.10.0-0.7
Total zone transitions, hab. session 20.91.21.70.9-1.21.2-1.21.31.3-0.8-0.91.3-0.70.81.3
Total locomotion distance, hab. session 20.20.20.70.3-0.50.4-0.40.60.6-0.40.00.60.1-0.00.8
Locomotion velocity, hab. session 20.40.51.10.5-0.80.7-0.70.90.8-0.6-0.30.8-0.10.21.1
Novel to familiar place preference ratio1.21.32.31.2-1.21.2-1.31.10.8-1.3-1.50.9-1.21.20.4
Novelty place preference1.31.32.61.2-1.21.1-1.21.00.8-1.2-1.60.8-1.41.40.2
Time in novel zone, NPP test0.60.61.40.8-0.70.7-0.80.60.4-0.8-1.20.4-1.11.0-0.1
Total zone transitions, NPP test0.40.62.00.4-0.70.8-0.70.81.1-0.6-0.31.10.10.01.4
Total locomotion distance, NPP test0.10.10.4-0.30.1-0.10.20.00.40.10.30.30.5-0.50.6
Locomotion velocity, NPP test0.30.41.10.3-0.50.5-0.50.61.0-0.6-0.30.8-0.00.11.0
Pavlov. Cond. lever latency3.14.05.71.7-1.61.9-2.02.01.9-2.2-2.31.9-2.42.41.1
Pavlov. Cond. magazine entry latency10.012.915.4-3.63.7-3.73.9-3.7-3.63.63.8-3.73.2-3.4-3.0
Pavlov. Cond. change in total contacts8.28.711.4-2.93.2-3.23.3-3.4-2.83.22.5-3.21.7-1.9-3.3
Pavlov. Cond. index score8.210.512.8-3.23.2-3.33.5-3.3-3.13.43.6-3.23.2-3.3-2.5
Pavlov. Cond. latency score6.38.010.2-2.72.7-2.83.0-2.9-2.83.03.2-2.83.0-3.0-2.0
Pavlov. Cond. lever contacts2.73.25.0-1.51.4-1.71.7-1.8-1.71.92.2-1.62.2-2.2-0.9
Pavlov. Cond. magazine entry number12.015.119.04.0-4.24.1-4.44.23.7-4.0-3.94.0-3.13.33.5
Pavlov. Cond. intertrial magazine entries1.61.92.61.4-1.41.5-1.51.61.3-1.2-1.61.3-1.41.50.8
Pavlov. Cond. lever-magazine prob. diff.9.011.313.3-3.33.4-3.53.7-3.5-3.33.63.6-3.43.1-3.2-2.7
Pavlov. Cond. response bias8.910.913.4-3.33.5-3.53.7-3.5-3.23.53.3-3.42.7-2.8-3.0
Bone: apparent density2.54.15.3-2.12.3-2.02.2-2.1-1.92.02.0-2.02.0-2.0-1.6
Bone surface0.10.20.9-0.20.3-0.20.2-0.4-0.10.20.7-0.11.0-0.90.4
Bone volume0.50.82.4-0.70.8-0.60.7-0.7-0.50.51.2-0.41.5-1.40.3
Bone: connectivity density3.25.16.5-2.42.5-2.22.4-2.3-2.22.32.1-2.42.0-2.0-2.0
Bone: cortical apparent density5.47.011.4-2.83.1-3.03.2-2.6-2.63.01.9-2.90.8-1.1-3.4
Bone: cortical area0.00.10.1-0.30.4-0.20.3-0.2-0.20.10.4-0.20.2-0.2-0.2
Bone: cortical porosity0.30.30.9-0.40.4-0.30.3-0.4-0.50.50.9-0.30.9-0.90.4
Bone: cortical porosity0.30.30.9-0.30.2-0.10.2-0.2-0.30.30.9-0.10.9-0.90.6
Bone: cortical thickness0.71.22.1-1.31.4-1.11.2-0.8-1.21.10.8-1.20.2-0.4-1.5
Bone: cortical thickness4.55.37.9-2.62.8-2.62.7-2.2-2.22.31.7-2.61.1-1.3-2.7
Bone: cortical tissue density5.47.011.3-2.83.1-3.03.2-2.7-2.63.11.9-2.90.8-1.1-3.4
Bone: elastic displacement0.00.00.00.00.00.0-0.00.10.00.10.00.0-0.10.1-0.0
Bone: elastic work0.20.20.7-0.50.6-0.30.4-0.2-0.40.30.8-0.30.6-0.6-0.1
Bone: endosteal estimation1.63.57.72.0-2.11.9-2.11.52.0-2.2-1.12.2-0.20.52.8
Bone: endosteal perimeter1.02.03.01.6-1.61.5-1.61.11.6-1.7-1.21.6-0.50.71.7
Bone: final force0.81.32.8-1.11.2-1.01.1-0.9-1.00.71.7-0.81.6-1.60.1
Bone: final moment0.61.02.4-0.91.0-0.80.9-0.8-0.80.61.6-0.61.5-1.50.2
Bone: marrow area1.53.27.12.0-2.01.8-2.01.52.0-2.1-1.12.1-0.20.42.7
Bone: maximum diameter0.10.10.3-0.20.3-0.20.2-0.4-0.30.00.5-0.20.6-0.5-0.1
Bone: maximum force0.10.10.60.1-0.00.0-0.10.00.0-0.20.50.30.6-0.60.8
Bone: maximum moment0.10.20.80.3-0.20.2-0.30.10.3-0.40.40.50.5-0.40.9
Bone: minimum diameter0.40.71.31.1-1.00.9-1.00.70.9-1.0-0.41.0-0.20.31.2
Bone: periosteal estimation0.20.41.40.6-0.60.5-0.60.30.6-0.80.00.70.4-0.21.2
Bone: periosteal perimeter0.50.82.00.9-1.01.0-1.00.61.0-1.2-0.31.10.00.11.4
Bone: post-yield work1.42.02.51.4-1.51.5-1.61.21.5-1.6-1.31.6-1.01.11.5
Bone: stiffness0.00.10.3-0.10.1-0.10.1-0.1-0.0-0.30.30.20.4-0.40.5
Bone: tissue strength1.11.11.41.1-1.21.1-1.21.01.0-1.1-0.81.1-0.90.91.1
Bone: trabecular number5.68.710.2-3.03.2-3.03.2-2.9-2.92.93.1-3.02.9-3.0-2.1
Bone: trabecular spacing1.31.73.71.3-1.51.3-1.41.41.5-1.3-0.81.6-0.30.41.9
Bone: trabecular thickness0.10.20.3-0.40.5-0.40.5-0.5-0.20.30.4-0.40.5-0.4-0.4
Bone: trabecular tissue density0.40.62.20.2-0.00.2-0.20.30.2-0.1-1.10.0-1.51.4-1.1
Breakpoint value in progressive ratio session0.20.20.50.2-0.40.2-0.20.7-0.6-0.20.5-0.50.5-0.5-0.3
Distance traveled before self-admin0.10.10.20.3-0.2-0.30.1-0.1-0.2-0.20.5-0.00.5-0.40.4
Distance traveled after self-admin1.21.43.71.9-1.60.8-1.20.61.0-1.3-0.91.2-0.40.51.4
Delta time in closed arm before/after self-admin3.53.34.81.7-1.72.0-2.02.12.2-1.9-1.72.0-1.11.22.0
Delta time in open arm before/after self-admin0.00.00.10.10.10.0-0.0-0.1-0.00.10.10.1-0.30.2-0.1
Diff in mean of infusions in LGA sessions0.30.30.80.7-0.90.6-0.60.8-0.3-0.70.2-0.20.5-0.50.0
Extinction: sum of active levers before priming1.51.52.61.3-1.31.6-1.61.01.2-1.3-0.91.4-0.40.51.6
Active lever presses in extinction session 63.02.96.9-1.41.6-1.21.3-1.2-1.51.42.5-1.42.6-2.6-0.2
Delta distance traveled before/after self-admin1.61.72.31.4-1.31.3-1.51.21.3-1.3-1.51.3-1.11.21.1
Delta ambulatory time before/after self-admin1.11.21.91.4-1.21.2-1.40.71.1-1.1-1.31.2-0.50.61.2
Time in closed arm before self-admin1.01.14.2-0.20.6-1.41.1-2.1-0.91.10.1-1.0-0.20.1-1.4
Time in closed arm after self-admin0.91.02.61.0-0.60.3-0.60.10.9-0.8-1.60.8-1.61.60.0
Time in open arm before self-admin1.81.96.20.9-1.11.7-1.52.51.3-1.5-1.01.3-0.50.51.4
Time in open arm after self-admin0.50.51.50.4-0.61.0-0.91.20.8-0.6-0.40.6-0.30.40.6
Sum of active levers in priming session hrs 5-60.50.51.2-0.81.1-0.50.6-0.4-0.50.80.9-0.60.8-0.8-0.4
Time to tail flick, vehicle, before self-admin0.00.00.1-0.2-0.3-0.20.2-0.3-0.10.10.40.10.1-0.10.1
Time to tail flick, vehicle, after self-admin0.10.10.5-0.2-0.2-0.10.20.1-0.20.30.6-0.20.7-0.70.1
Time to tail flick, test, before self-admin1.41.42.80.8-1.21.7-1.51.41.1-1.5-0.91.2-0.60.71.1
Time to tail flick, test, after self-admin0.30.31.0-0.1-0.3-0.70.5-0.30.10.91.0-0.10.6-0.60.2
Delta time to tail flick, vehicle, before/after SA0.60.62.4-0.50.3-0.30.4-0.4-0.40.61.1-0.61.5-1.50.1
Delta time to tail flick, test, before/after SA2.32.14.8-1.00.9-2.11.8-1.5-1.02.21.6-1.30.9-1.0-1.1
Ambulatory time before self-admin0.00.00.10.1-0.1-0.20.1-0.2-0.1-0.30.20.1-0.00.00.3
Ambulatory time after self-admin1.82.04.82.2-1.91.1-1.60.41.2-1.7-1.01.5-0.30.42.0
Total heroin consumption2.93.47.5-1.91.6-1.51.8-1.1-1.71.32.7-1.82.5-2.5-0.9
Area under the delay curve0.20.20.6-0.40.5-0.30.4-0.8-0.20.60.4-0.40.1-0.1-0.3
Delay disc. indifference point, 0s delay0.91.01.8-0.70.7-1.11.0-1.0-0.91.31.0-1.10.6-0.7-1.2
Delay disc. indifference point, 16s delay0.40.40.9-0.31.0-0.50.5-0.90.10.7-0.4-0.4-0.90.7-0.9
Delay disc. indifference point, 2s delay1.01.12.6-1.00.7-1.01.1-0.8-0.91.31.6-0.91.1-1.2-0.4
Delay disc. indifference point, 24s delay0.20.20.40.4-0.40.3-0.4-0.30.4-0.2-0.60.3-0.70.60.2
Delay disc. indifference point, 4s delay0.80.81.5-1.01.1-0.80.9-0.8-0.90.91.2-0.90.7-0.8-0.6
Delay disc. indifference point, 8s delay0.10.10.6-0.40.3-0.00.2-0.8-0.20.30.2-0.20.1-0.1-0.1
Delay discount exponential model param0.10.10.40.3-0.30.1-0.20.60.1-0.4-0.30.20.1-0.00.1
Delay discount hyperbolic model param0.10.10.50.4-0.40.3-0.30.70.2-0.5-0.50.3-0.10.10.2
Fecal boli incidents, locomotor time 10.30.31.20.7-1.10.3-0.50.80.4-0.2-0.30.6-0.30.30.8
Change in fecal boli incidents, locomotor task0.10.10.20.2-0.00.3-0.30.40.30.1-0.20.2-0.30.30.1
Time >=10cm from walls, locomotor time 10.20.20.5-0.10.1-0.20.20.1-0.30.7-0.5-0.3-0.70.6-0.7
Bouts of movement, locomotor time 10.30.41.60.4-0.30.7-0.70.50.3-1.3-0.30.50.2-0.10.9
Total resting periods, locomotor time 10.80.92.50.7-0.71.0-1.01.00.8-1.6-0.51.00.10.01.5
Rest time, locomotor task time 10.10.20.5-0.20.0-0.30.3-0.6-0.2-0.20.4-0.10.7-0.70.2
Distance moved, locomotor task time 10.10.10.5-0.10.2-0.20.20.00.10.7-0.1-0.1-0.30.2-0.4
Vertical activity count, locomotor time 10.30.31.70.4-0.50.6-0.61.30.4-0.0-0.20.5-0.50.40.4
Time >=10cm from walls, locomotor time 20.90.91.7-1.21.0-0.81.00.2-1.31.30.8-1.00.5-0.7-1.1
Bouts of movement, locomotor time 20.20.30.8-0.40.8-0.30.3-0.4-0.80.1-0.2-0.60.0-0.1-0.9
Total resting periods, locomotor time 20.20.20.6-0.30.7-0.10.2-0.2-0.6-0.1-0.3-0.5-0.20.1-0.8
Rest time, locomotor task time 20.60.71.10.8-0.91.0-1.01.00.8-1.0-0.60.9-0.40.50.9
Distance moved, locomotor task time 20.10.10.20.4-0.20.2-0.30.30.50.4-0.30.4-0.20.20.3
Vertical activity count, locomotor time 20.40.41.00.8-0.80.6-0.71.00.5-0.2-0.60.7-0.60.60.6
Weight adjusted by age0.40.41.40.6-0.60.7-0.71.20.3-0.9-0.00.30.7-0.60.7
Seeking ratio, delayed vs. immediate footshock0.40.51.3-0.60.6-0.70.70.4-0.30.8-0.2-0.5-1.10.9-1.1
Locomotion in novel chamber5.26.49.9-2.32.6-3.02.9-1.8-2.63.12.7-2.71.8-2.0-2.4
Locomotion in novel chamber post-restriction1.61.94.6-1.10.7-1.21.2-1.1-1.41.12.2-1.22.0-2.0-0.3
Progressive ratio0.20.20.5-0.10.0-0.30.20.2-0.50.70.6-0.40.7-0.7-0.0
Food seeking constrained by brief footshock0.40.51.4-0.50.6-0.40.5-1.2-0.40.40.9-0.61.0-0.9-0.2
Seeking ratio, punishment vs. effort0.10.10.6-0.10.20.1-0.0-0.80.3-0.4-0.20.2-0.30.3-0.0
Run reversals in cocaine runway, females2.92.95.11.3-0.91.7-1.71.81.4-1.9-2.01.6-2.32.20.8
Run reversals in cocaine runway, males0.50.50.7-0.80.8-0.70.8-0.8-0.50.80.7-0.60.3-0.4-0.5
Latency to leave start box in cocaine runway1.31.42.31.1-0.91.0-1.11.51.3-1.0-1.11.4-1.31.31.2
Latency to leave start box in cocaine runway, F1.21.32.51.1-0.81.1-1.21.61.3-1.2-0.91.3-0.91.01.3
Latency to leave start box in cocaine runway, M0.30.30.6-0.40.5-0.60.6-0.6-0.20.8-0.2-0.4-0.50.5-0.7
Cd content in liver0.20.20.5-0.60.7-0.40.5-0.6-0.40.60.5-0.30.3-0.3-0.2
Co content in liver0.60.71.30.7-0.70.7-0.80.81.0-0.8-1.10.8-0.91.00.2
Cu content in liver0.10.10.2-0.30.5-0.10.10.00.00.1-0.4-0.1-0.50.4-0.5
Fe content in liver0.81.01.91.1-1.11.1-1.21.10.9-1.0-0.61.1-0.20.31.4
K content in liver1.41.42.0-1.21.3-1.01.1-1.1-1.41.21.2-1.41.0-1.1-1.1
Mg content in liver1.01.02.9-1.11.2-0.80.9-1.0-1.11.00.2-1.2-0.20.1-1.7
Mn content in liver2.32.64.4-1.82.0-1.51.8-1.7-1.71.61.1-1.90.7-0.9-2.1
Na content in liver0.70.72.2-0.60.5-0.50.5-0.5-0.80.61.2-0.61.5-1.40.2
Rb content in liver1.31.72.5-1.31.6-1.41.5-1.5-1.21.61.0-1.40.6-0.7-1.4
Se content in liver5.76.98.8-2.72.9-2.72.9-2.8-2.82.92.1-2.91.6-1.8-3.0
Sr content in liver0.20.10.7-0.30.3-0.30.3-0.2-0.20.2-0.1-0.4-0.40.4-0.8
Zn content in liver3.53.95.1-2.12.2-2.12.3-2.2-1.81.91.8-2.11.4-1.5-2.0