Alg6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000098114 0.02 0.02 9.3e-03 0.01 0.01 -0 -0 7.0e-02 6.1e-02 5.9e-01 4.2e-01
2 Adipose alternative polyA ENSRNOT00000107656 0.02 0.02 9.7e-03 0.01 0.01 -0 -0 7.1e-02 5.4e-02 4.7e-01 3.9e-01
3 Adipose gene expression ENSRNOG00000009045 0.1 0.06 8.8e-08 0.05 0.04 0.05 0.04 3.7e-06 1.4e-05 6.3e-06 9.6e-06
4 Brain mRNA stability ENSRNOG00000009045 0.07 0.05 1.4e-06 0.07 0.07 0.07 0.07 1.9e-07 4.0e-07 5.4e-07 2.5e-07
5 Eye gene expression ENSRNOG00000009045 0.32 0.18 2.1e-03 0.12 0.05 0.01 0.06 6.9e-03 6.3e-02 2.2e-01 4.5e-02
6 Liver gene expression ENSRNOG00000009045 0.37 0.16 4.6e-15 0.09 0.06 0.07 0.09 3.7e-10 1.1e-07 5.6e-08 9.3e-10
7 PL intron excision ratio chr5:114443858:114452985 0.04 0.03 4.9e-04 0.05 0.05 0.05 0.04 2.1e-04 1.1e-04 1.6e-04 2.2e-04
8 PL mRNA stability ENSRNOG00000009045 0.08 0.09 9.7e-03 0 0.01 0.02 0.03 2.5e-01 2.6e-02 2.0e-02 3.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.20.61.40.7-0.7-0.80.3-0.5-0.90.3-1.2
BMI without tail0.20.51.00.7-0.7-0.60.6-0.8-1.00.70.2
Body weight0.10.21.1-0.20.20.1-0.40.20.4-0.5-1.1
Epididymis fat weight1.84.24.9-2.12.12.0-2.22.01.5-2.2-2.2
Glucose0.10.20.50.3-0.3-0.7-0.20.1-0.5-0.0-0.7
Heart weight2.84.05.3-2.22.21.7-2.22.21.8-2.3-1.0
Left kidney weight0.41.12.6-1.01.00.4-1.00.90.9-1.4-1.6
Right kidney weight0.41.22.4-1.21.21.0-0.80.71.5-1.4-0.9
Tail length0.51.52.6-1.41.41.6-1.11.11.4-1.10.3
Length with tail0.31.22.1-1.21.21.3-0.91.01.4-1.1-0.1
Length without tail0.10.20.7-0.20.20.2-0.00.10.6-0.4-0.8
Liver weight, left1.82.93.9-1.81.81.8-1.51.52.0-1.8-1.3
Liver weight, right5.99.912.1-3.13.12.7-3.13.22.9-3.4-3.5
Parametrial fat weight2.75.28.22.5-2.5-1.92.9-2.7-2.02.40.4
Retroperitoneal fat weight0.20.61.3-0.80.80.6-0.70.70.4-0.9-1.1
Intraocular pressure0.00.10.3-0.00.00.60.2-0.30.20.1-0.1
Extensor digitorum longus weight0.51.92.9-1.41.41.0-1.61.51.1-1.7-1.4
Soleus weight0.10.30.7-0.50.50.8-0.50.50.5-0.50.0
Tibialis anterior weight7.325.228.85.4-5.4-5.25.2-5.3-4.95.23.3
Tibia length2.26.38.6-2.72.72.4-2.62.52.9-2.7-1.3
Number of licking bursts0.10.10.20.2-0.2-0.40.1-0.2-0.40.1-0.4
Food consumed during 24 hour testing period0.40.51.4-0.60.61.2-0.20.30.6-0.40.9
Times rat made contact with spout0.20.20.60.4-0.4-0.70.2-0.0-0.80.2-0.0
Mean time between licks in bursts5.57.710.7-3.03.02.9-2.72.73.3-2.9-1.3
Mean num. licks in bursts0.10.10.30.2-0.2-0.20.10.0-0.20.20.6
Std. dev. time between licks in bursts0.10.10.4-0.20.20.60.1-0.20.6-0.3-0.3
Water consumed over 24 hours0.30.31.20.4-0.4-0.40.5-0.3-0.60.1-1.1
Indifference point 0 sec6.610.716.73.5-3.5-4.13.2-3.1-3.43.21.5
Indifference point AUC1.11.21.61.2-1.2-1.01.1-1.1-1.31.20.6
Indifference point function ln k0.71.01.9-1.01.01.4-0.90.81.2-1.0-0.6
Indifference point function log k0.71.01.9-1.01.01.4-0.90.81.2-1.0-0.6
Delay discounting total patch changes 0 sec6.19.815.43.4-3.4-3.93.0-2.9-3.33.11.4
Delay discounting total patch changes 12 sec1.82.44.81.6-1.6-2.21.5-1.3-1.71.40.3
Delay discounting total patch changes 18 sec3.14.07.62.2-2.2-2.81.8-1.7-2.21.90.3
Delay discounting total patch changes 24 sec1.51.93.31.5-1.5-1.81.2-1.2-1.51.2-0.0
Delay discounting total patch changes 6 sec4.26.411.32.6-2.6-3.12.0-1.9-3.42.31.8
Delay discounting time to switch 0 sec0.91.42.3-1.41.41.1-1.41.50.8-1.3-0.3
Delay discounting water rate 0 sec1.32.13.01.6-1.6-1.21.6-1.7-1.31.50.7
Delay discounting water rate 12 sec2.63.85.32.1-2.1-1.92.2-2.3-2.01.90.5
Delay discounting water rate 18 sec0.30.51.10.7-0.7-0.60.5-0.7-1.10.50.1
Delay discounting water rate 24 sec0.00.00.10.2-0.20.10.2-0.3-0.2-0.0-0.4
Delay discounting water rate 6 sec0.00.00.10.1-0.10.20.2-0.30.30.10.2
Locomotor activity0.10.10.70.3-0.3-0.80.2-0.3-0.20.3-0.1
Locomotor testing distance1.83.04.91.8-1.8-2.21.7-1.8-1.51.71.0
Locomotor testing rearing0.10.20.90.3-0.3-1.00.1-0.1-0.50.2-0.5
Light reinforcement 10.30.51.8-0.60.60.4-0.70.70.2-0.7-1.3
Light reinforcement 20.60.71.9-0.70.71.0-0.70.70.7-0.8-1.4
Reaction time number correct0.10.20.5-0.00.00.70.3-0.40.10.30.6
Reaction time mean minus median1.01.32.51.2-1.2-1.60.8-0.8-1.31.11.2
Reaction time mean minus median AUC0.30.40.80.5-0.5-0.90.3-0.3-0.60.50.9
Reaction time num false alarms0.40.51.20.6-0.6-0.50.6-0.6-0.50.81.1
Reaction time num false alarms AUC1.01.42.71.1-1.1-1.01.1-1.0-1.01.31.7
Reaction time trials correct on left0.10.20.5-0.00.00.70.3-0.40.10.30.6
Reaction time trials on left0.10.20.40.1-0.10.60.3-0.50.00.30.6
Reaction time mean0.71.01.61.1-1.1-1.10.9-0.8-1.30.90.6
Reaction time mean AUC0.30.40.90.7-0.7-0.70.6-0.5-1.00.60.0
Median of all reaction times0.50.71.00.9-0.9-0.70.9-0.8-1.00.80.5
Reaction time omissions0.70.92.30.9-0.9-1.50.6-0.6-1.50.70.1
Reaction time false alarm rate1.11.52.01.2-1.2-1.41.1-1.0-1.21.31.4
Reaction time premature initiation rate0.10.20.3-0.50.50.0-0.50.50.2-0.5-0.0
Reaction time premature initiations0.20.30.4-0.60.60.5-0.50.40.5-0.6-0.0
Std. dev. reaction times2.33.25.11.9-1.9-2.31.6-1.6-2.01.71.2
Reaction time trials completed0.10.20.40.1-0.10.60.3-0.50.00.30.6
Reaction time trials AUC0.10.10.40.1-0.10.60.3-0.50.00.40.6
Social response proportion0.30.30.70.4-0.40.10.5-0.5-0.90.60.5
Social responses0.30.40.8-0.50.5-0.0-0.90.9-0.6-0.7-0.2
Social time0.10.20.40.2-0.2-0.6-0.40.4-0.60.0-0.6
Conditioned locomotion0.10.20.9-0.20.1-0.2-0.20.3-0.2-0.4-0.9
Cocaine response after cond. corrected0.70.81.70.7-0.7-1.30.7-0.7-1.30.70.9
Cocaine response after cond. not corrected0.70.81.90.7-0.7-1.40.6-0.6-1.30.60.9
Cocaine response before conditioning0.00.00.1-0.00.0-0.0-0.00.10.10.00.3
Saline control response0.00.00.20.0-0.00.0-0.30.4-0.1-0.0-0.1
Condit. Reinf. active minus inactive responses0.70.91.4-1.01.00.8-1.11.20.8-1.0-0.5
Condit. Reinf. active-inactive response ratio0.20.20.5-0.40.40.1-0.70.70.2-0.4-0.2
Condit. Reinf. active responses0.40.50.9-0.80.80.5-0.80.90.6-0.8-0.3
Condit. Reinf. inactive responses0.81.01.3-1.11.11.0-1.01.21.0-1.1-0.3
Condit. Reinf. lever presses3.14.34.82.1-2.1-2.02.2-2.0-2.22.21.7
Condit. Reinf. lever reinforcers received0.10.10.3-0.30.30.1-0.40.50.2-0.30.2
Pavlov. Cond. lever latency1.62.14.1-1.41.41.3-1.21.11.6-1.5-2.0
Pavlov. Cond. magazine entry latency1.82.12.41.5-1.5-1.11.4-1.4-1.51.51.5
Pavlov. Cond. change in total contacts2.12.94.21.6-1.6-1.31.7-1.6-1.81.82.0
Pavlov. Cond. index score1.82.42.81.6-1.6-1.31.5-1.4-1.61.61.7
Pavlov. Cond. latency score1.41.82.11.4-1.4-1.11.3-1.2-1.51.41.4
Pavlov. Cond. lever contacts2.73.75.91.9-1.8-1.61.8-1.7-2.02.02.4
Pavlov. Cond. magazine entry number0.70.91.7-1.01.00.6-0.90.71.0-1.0-1.3
Pavlov. Cond. intertrial magazine entries1.31.62.1-1.41.41.4-1.41.31.3-1.3-0.4
Pavlov. Cond. lever-magazine prob. diff.1.82.33.01.5-1.5-1.21.5-1.4-1.61.61.7
Pavlov. Cond. response bias2.33.25.91.7-1.7-1.51.6-1.5-1.81.82.4
Conditioned reinforcement - actives0.10.10.3-0.10.10.0-0.50.3-0.6-0.20.1
Conditioned reinforcement - inactives0.30.31.1-0.40.40.1-0.50.40.7-0.6-1.1
Conditioned locomotion0.20.20.60.1-0.1-0.6-0.50.4-0.7-0.2-0.8
Intermittent access intake day 1-15 change0.80.81.2-0.90.91.1-1.00.80.9-0.70.7
Intermittent access intake escalation0.70.71.0-0.80.81.0-0.90.80.7-0.60.8
Intermittent access intake escalation 20.60.61.1-0.80.80.7-1.00.90.5-0.70.7
Intermitt. access day 1 inactive lever presses0.80.81.41.0-1.0-0.81.2-1.2-0.30.8-0.6
Intermitt. access day 15 inactive lever presses0.80.91.1-1.01.00.8-0.91.01.0-1.1-0.7
Intermitt. access escalation Index1.21.15.90.4-0.30.60.8-0.60.30.92.4
Intermittent access day 1 total infusions0.10.10.50.1-0.1-0.3-0.10.2-0.70.1-0.1
Intermittent access day 15 total infusions0.20.30.6-0.50.50.5-0.80.7-0.3-0.40.1
Intermittent access terminal intake (last 3 days)0.00.00.1-0.20.20.2-0.40.2-0.3-0.10.1
Intermittent access total infusions0.20.20.4-0.30.3-0.0-0.60.6-0.7-0.3-0.4
Intermittent access day 1 locomotion0.70.73.10.7-0.7-0.80.3-0.3-1.80.70.1
Intermittent access day 15 total locomotion0.30.41.60.6-0.6-0.50.0-0.2-1.30.60.2
Intermittent access total locomotion0.30.31.70.5-0.5-0.5-0.0-0.1-1.30.4-0.1
Intermittent access standard deviation0.80.91.8-0.90.90.4-1.31.3-0.2-1.0-1.0
Cocaine induced anxiety0.30.31.6-0.40.50.5-0.10.10.4-0.11.3
Post-drug Anxiety1.11.32.0-1.31.31.3-0.90.81.4-1.10.2
Baseline Anxiety0.91.02.3-0.80.80.8-0.80.91.1-1.0-1.5
Lifetime Intake0.10.10.5-0.00.0-0.2-0.30.3-0.70.10.3
Incentive Sensitization - Responses0.50.51.60.6-0.6-0.50.3-0.4-1.30.70.9
Incentive Sensitization - Breakpoint0.60.61.80.7-0.7-0.40.4-0.5-1.40.81.0
Progressive ratio test 1 active lever presses2.42.53.7-1.61.61.6-1.91.80.9-1.6-1.2
Progressive ratio test 1 breakpoint3.23.34.8-1.91.91.9-2.22.11.2-1.8-1.5
Progressive ratio test 1 inactive lever presses0.60.71.1-0.80.80.8-1.11.00.2-0.8-0.7
Progressive ratio test 2 active lever presses0.20.21.4-0.00.0-0.1-0.50.4-1.20.10.2
Progressive ratio test 2 breakpoint0.20.21.2-0.10.1-0.0-0.60.4-1.1-0.00.0
Progressive ratio test 2 inactive lever presses0.20.20.80.3-0.3-0.3-0.0-0.1-0.70.40.9
Total sessions with >9 infusions0.91.01.5-1.11.11.0-1.21.20.8-0.9-0.7
Short access day 1 total inactive lever presses0.50.51.40.7-0.7-1.20.4-0.4-1.10.5-0.1
Short access day 10 total inactive lever presses1.11.22.51.2-1.2-0.91.6-1.5-0.21.00.1
Short access day 1 total infusions0.00.00.3-0.00.00.0-0.00.00.10.20.5
Short access day 10 total infusions0.20.31.30.1-0.1-0.6-0.30.1-1.1-0.0-0.6
Short access total infusions0.10.10.40.2-0.2-0.40.0-0.0-0.60.40.6
Short access day 1 locomotion0.60.61.20.8-0.8-0.90.5-0.6-1.10.90.7
Short access day 10 total locomotion0.60.72.60.6-0.6-1.20.1-0.1-1.60.4-0.7
Short access total locomotion0.10.10.4-0.10.1-0.3-0.40.4-0.6-0.1-0.2
Compulsive drug intake4.94.85.92.4-2.4-2.32.4-2.2-2.02.31.5
One hour access (0.3 mA shock)0.70.83.80.6-0.6-1.00.3-0.3-2.00.60.6
One hour access (shock baseline)1.21.42.5-1.31.31.1-1.61.40.0-1.3-0.7
Number of responses in last shaping day0.70.73.40.3-0.3-1.1-0.1-0.3-0.6-0.1-1.8
Context. condit. distance diff. score3.13.75.7-1.91.91.5-1.81.81.9-2.1-2.4
Locomotion velocity, session 10.40.41.40.6-0.6-1.20.3-0.2-1.00.40.0
Locomotion distance, session 10.40.50.8-0.80.80.4-0.90.90.5-0.9-0.3
Locomotion velocity, session 20.10.10.60.1-0.1-0.00.2-0.20.30.30.8
Locomotion distance, session 20.20.41.00.5-0.5-0.60.5-0.5-0.40.51.0
Locomotion velocity, session 30.00.00.1-0.20.20.3-0.10.3-0.1-0.3-0.1
Locomotion distance, session 30.00.00.10.0-0.0-0.10.20.0-0.2-0.00.4
Stereotopy head waving bouts, day 30.60.71.1-1.01.01.0-0.60.61.1-0.8-0.2
Stereotopy head waving duration, day 31.01.22.0-1.21.21.1-1.11.01.4-1.0-0.2
Locomotion velocity, session 70.90.91.3-1.21.20.9-0.90.91.1-1.0-0.5
Locomotion distance, session 70.50.70.8-0.90.90.9-0.70.80.8-0.8-0.8
Stereotopy head waving bouts, day 70.70.81.50.9-0.9-1.20.9-0.9-0.70.80.6
Stereotopy head waving duration, day 71.31.62.81.2-1.3-1.71.1-1.1-1.11.21.1
Locomotion velocity, session 80.30.30.5-0.50.5-0.3-0.70.70.4-0.6-0.6
Locomotion distance, session 80.71.01.3-1.11.10.7-1.11.10.8-1.2-1.0
Degree of sensitization distance0.10.10.60.0-0.00.0-0.0-0.10.00.0-0.8
Degree of sensitization stereotypy1.21.32.11.2-1.2-1.51.0-1.0-1.11.11.0
Condit. Reinf. active minus inactive responses0.50.61.80.8-0.8-0.60.5-0.6-1.40.70.1
Condit. Reinf. active-inactive response ratio0.30.31.30.4-0.5-0.70.0-0.2-1.10.2-0.1
Condit. Reinf. active responses1.21.53.61.3-1.3-1.11.0-1.1-1.91.20.4
Condit. Reinf. inactive responses0.50.61.30.9-0.9-0.70.6-0.5-1.10.80.3
Incentive salience index mean0.70.92.81.0-1.0-0.90.5-0.7-1.70.80.1
Condit. Reinf. lever presses0.20.20.90.3-0.3-0.6-0.30.2-1.00.1-0.4
Time in familiar zone, hab. session 12.52.43.5-1.51.50.8-1.61.61.5-1.7-1.9
Time in novel zone, hab. session 15.65.57.02.5-2.5-1.92.5-2.6-2.12.61.8
Total zone transitions, hab. session 10.91.31.7-1.31.31.1-1.31.30.9-1.2-0.6
Total locomotion distance, hab. session 10.20.30.7-0.60.60.7-0.20.20.8-0.50.1
Locomotion velocity, hab. session 10.20.20.4-0.60.60.6-0.30.30.6-0.50.3
Time in familiar zone, hab. session 20.40.40.6-0.60.60.0-0.80.80.0-0.8-0.8
Time in novel zone, hab. session 20.70.71.10.8-0.8-0.51.0-1.0-0.31.00.8
Total zone transitions, hab. session 24.55.87.3-2.72.72.5-2.52.52.3-2.6-1.2
Total locomotion distance, hab. session 22.73.64.8-2.22.21.8-1.81.82.1-2.0-0.7
Locomotion velocity, hab. session 22.33.14.2-2.02.01.8-1.71.62.0-1.8-0.5
Novel to familiar place preference ratio0.80.91.21.1-1.1-1.00.9-1.0-0.81.10.1
Novelty place preference0.40.50.70.8-0.8-0.70.7-0.7-0.40.80.1
Time in novel zone, NPP test0.60.60.91.0-1.0-0.80.8-0.8-0.50.9-0.0
Total zone transitions, NPP test1.31.92.7-1.61.61.3-1.61.61.0-1.5-0.5
Total locomotion distance, NPP test0.50.71.1-1.01.01.1-0.60.71.0-0.80.3
Locomotion velocity, NPP test0.50.71.1-1.01.01.0-0.70.71.0-0.80.3
Pavlov. Cond. lever latency1.11.33.6-1.21.21.6-0.80.71.9-0.90.4
Pavlov. Cond. magazine entry latency0.20.30.6-0.30.3-0.2-0.70.8-0.4-0.4-0.7
Pavlov. Cond. change in total contacts0.70.82.20.9-0.9-0.90.7-0.6-1.50.7-0.4
Pavlov. Cond. index score0.50.61.90.6-0.6-1.30.10.0-1.40.3-0.6
Pavlov. Cond. latency score0.50.62.00.7-0.7-1.30.2-0.1-1.40.4-0.6
Pavlov. Cond. lever contacts0.40.51.90.6-0.6-1.00.3-0.1-1.40.3-0.5
Pavlov. Cond. magazine entry number0.30.40.90.4-0.40.20.9-0.90.50.50.7
Pavlov. Cond. intertrial magazine entries0.50.72.5-0.70.71.6-0.70.80.4-0.40.5
Pavlov. Cond. lever-magazine prob. diff.0.40.52.00.6-0.6-1.20.10.0-1.40.3-0.5
Pavlov. Cond. response bias0.20.31.00.1-0.1-0.6-0.30.4-1.0-0.1-0.8
Bone: apparent density0.30.41.6-0.50.50.6-0.40.50.6-0.31.3
Bone surface1.73.04.21.7-1.7-1.41.9-1.9-1.21.82.0
Bone volume0.61.03.60.7-0.7-0.41.0-1.0-0.40.91.9
Bone: connectivity density2.13.24.71.8-1.8-1.71.8-1.8-1.61.82.2
Bone: cortical apparent density6.88.912.1-3.23.23.5-3.23.22.5-3.1-1.1
Bone: cortical area0.20.20.40.5-0.50.10.5-0.4-0.50.60.6
Bone: cortical porosity0.50.50.90.8-0.8-0.90.7-0.6-0.70.7-0.1
Bone: cortical porosity0.70.81.41.0-1.0-1.20.8-0.7-0.90.8-0.3
Bone: cortical thickness0.20.40.9-0.50.50.9-0.70.70.3-0.5-0.6
Bone: cortical thickness0.10.10.6-0.30.30.2-0.30.20.3-0.3-0.8
Bone: cortical tissue density6.68.611.5-3.23.23.4-3.23.22.5-3.0-1.2
Bone: elastic displacement0.80.91.2-0.90.90.9-1.00.90.8-1.0-1.1
Bone: elastic work1.11.51.9-1.11.11.1-1.31.21.2-1.2-1.4
Bone: endosteal estimation0.40.91.40.9-0.9-0.81.2-1.1-0.60.91.0
Bone: endosteal perimeter1.32.64.21.5-1.5-1.41.8-1.7-1.01.82.0
Bone: final force0.40.60.9-0.90.90.9-0.80.80.8-0.80.0
Bone: final moment0.00.00.1-0.20.20.3-0.20.20.2-0.20.2
Bone: marrow area0.40.81.20.8-0.8-0.81.1-1.0-0.60.90.9
Bone: maximum diameter0.71.32.51.0-1.0-0.61.2-1.1-1.01.21.6
Bone: maximum force0.10.10.2-0.40.40.5-0.40.40.4-0.30.2
Bone: maximum moment0.00.10.10.3-0.3-0.20.3-0.2-0.30.30.3
Bone: minimum diameter1.42.73.81.6-1.6-1.21.7-1.7-1.31.82.0
Bone: periosteal estimation0.40.91.30.9-0.9-0.51.2-1.1-0.71.11.0
Bone: periosteal perimeter0.81.33.01.1-1.1-0.71.1-1.0-1.01.21.7
Bone: post-yield work1.21.72.11.4-1.4-1.41.4-1.3-1.51.30.7
Bone: stiffness0.10.20.3-0.40.40.5-0.30.40.6-0.40.2
Bone: tissue strength0.90.91.50.9-0.9-0.80.8-0.6-1.21.01.1
Bone: trabecular number0.10.21.2-0.20.20.1-0.10.20.3-0.11.1
Bone: trabecular spacing0.10.20.9-0.10.10.4-0.20.1-0.3-0.3-0.9
Bone: trabecular thickness0.20.30.7-0.50.50.6-0.30.30.8-0.20.7
Bone: trabecular tissue density14.119.823.6-4.94.94.7-4.84.74.5-4.6-1.7
Breakpoint value in progressive ratio session0.50.61.8-0.70.70.4-0.50.80.2-0.9-1.3
Distance traveled before self-admin0.20.21.10.2-0.20.00.4-0.3-0.10.1-1.0
Distance traveled after self-admin1.21.31.81.1-1.1-1.11.3-1.2-1.11.10.9
Delta time in closed arm before/after self-admin0.30.31.00.5-0.5-0.60.4-0.3-0.30.3-1.0
Delta time in open arm before/after self-admin1.51.43.41.0-1.0-0.51.1-1.1-1.11.31.9
Diff in mean of infusions in LGA sessions0.40.51.8-0.50.50.2-0.60.60.5-0.8-1.3
Extinction: sum of active levers before priming0.90.92.0-0.90.91.0-0.50.61.4-0.9-1.1
Active lever presses in extinction session 60.50.43.00.0-0.0-0.20.00.3-0.4-0.4-1.7
Delta distance traveled before/after self-admin2.02.23.61.4-1.4-1.61.2-1.3-1.41.51.9
Delta ambulatory time before/after self-admin1.71.84.61.1-1.1-1.31.1-1.2-1.21.32.2
Time in closed arm before self-admin0.20.31.8-0.10.10.1-0.20.1-0.60.11.3
Time in closed arm after self-admin0.00.00.20.1-0.1-0.3-0.0-0.1-0.40.0-0.3
Time in open arm before self-admin0.20.30.90.4-0.4-0.60.4-0.4-0.10.2-1.0
Time in open arm after self-admin2.22.43.31.6-1.6-1.31.8-1.7-1.21.71.3
Sum of active levers in priming session hrs 5-62.52.44.3-1.51.51.3-1.21.41.6-1.8-2.1
Time to tail flick, vehicle, before self-admin1.81.82.41.6-1.6-1.31.5-1.4-1.31.5-0.0
Time to tail flick, vehicle, after self-admin1.11.21.91.0-1.0-0.81.3-1.2-0.81.21.4
Time to tail flick, test, before self-admin0.20.21.00.2-0.2-0.10.4-0.20.10.31.0
Time to tail flick, test, after self-admin0.10.10.30.0-0.00.50.5-0.30.50.20.4
Delta time to tail flick, vehicle, before/after SA0.90.91.4-1.11.11.0-0.70.71.2-0.90.7
Delta time to tail flick, test, before/after SA0.30.30.70.5-0.5-0.10.7-0.8-0.30.60.3
Ambulatory time before self-admin0.30.32.1-0.20.20.2-0.10.10.5-0.4-1.5
Ambulatory time after self-admin1.41.52.21.2-1.2-1.31.3-1.3-1.51.20.9
Total heroin consumption1.11.41.9-1.31.31.0-1.11.30.8-1.4-0.9
Area under the delay curve0.20.20.7-0.40.40.7-0.20.20.8-0.3-0.3
Delay disc. indifference point, 0s delay3.23.45.7-1.81.81.7-1.81.62.4-1.9-1.7
Delay disc. indifference point, 16s delay1.51.52.31.3-1.3-1.31.2-1.3-1.51.30.3
Delay disc. indifference point, 2s delay0.60.62.6-0.70.70.9-0.30.21.6-0.6-0.4
Delay disc. indifference point, 24s delay0.00.00.3-0.00.00.0-0.00.1-0.5-0.0-0.3
Delay disc. indifference point, 4s delay2.42.65.0-1.61.62.2-1.31.32.2-1.4-0.7
Delay disc. indifference point, 8s delay1.11.11.7-1.11.11.3-0.91.01.3-1.0-0.7
Delay discount exponential model param0.20.20.60.4-0.4-0.70.2-0.2-0.80.30.3
Delay discount hyperbolic model param0.40.41.00.6-0.6-0.90.3-0.3-1.00.40.3
Fecal boli incidents, locomotor time 10.10.10.40.1-0.1-0.2-0.30.1-0.60.10.2
Change in fecal boli incidents, locomotor task0.30.31.2-0.50.50.80.00.21.1-0.4-0.3
Time >=10cm from walls, locomotor time 10.20.20.50.4-0.4-0.10.7-0.70.10.50.2
Bouts of movement, locomotor time 10.50.61.60.6-0.6-1.30.3-0.4-0.70.1-1.2
Total resting periods, locomotor time 10.40.41.50.6-0.6-1.20.5-0.5-0.50.2-0.7
Rest time, locomotor task time 10.10.10.30.1-0.10.00.3-0.30.50.0-0.2
Distance moved, locomotor task time 10.20.30.4-0.50.50.6-0.70.60.5-0.4-0.2
Vertical activity count, locomotor time 10.10.10.5-0.20.20.70.0-0.00.40.10.3
Time >=10cm from walls, locomotor time 22.42.64.6-1.61.61.4-1.41.52.1-1.7-1.3
Bouts of movement, locomotor time 21.11.11.41.2-1.2-1.11.2-1.1-1.21.0-0.0
Total resting periods, locomotor time 21.11.21.51.2-1.2-1.11.2-1.2-1.21.00.0
Rest time, locomotor task time 20.40.40.90.7-0.6-0.10.9-0.9-0.50.80.1
Distance moved, locomotor task time 22.12.43.7-1.61.61.1-1.81.81.9-1.6-0.6
Vertical activity count, locomotor time 20.91.02.1-1.01.00.6-1.11.01.4-1.0-0.3
Weight adjusted by age1.82.02.81.4-1.4-1.01.7-1.5-0.71.61.7
Seeking ratio, delayed vs. immediate footshock0.20.31.70.1-0.1-0.30.1-0.30.3-0.2-1.3
Locomotion in novel chamber0.60.71.20.9-0.9-0.91.1-0.9-0.80.8-0.2
Locomotion in novel chamber post-restriction0.20.20.8-0.00.0-0.1-0.50.6-0.9-0.1-0.7
Progressive ratio0.20.30.4-0.60.60.6-0.70.60.4-0.4-0.1
Food seeking constrained by brief footshock4.95.96.4-2.52.52.5-2.52.42.5-2.4-2.2
Seeking ratio, punishment vs. effort0.91.11.3-1.01.00.9-1.01.01.1-1.1-1.1
Run reversals in cocaine runway, females0.00.00.10.1-0.1-0.3-0.0-0.10.4-0.1-0.3
Run reversals in cocaine runway, males0.60.60.70.8-0.8-0.80.7-0.8-0.80.70.2
Latency to leave start box in cocaine runway0.60.71.2-0.80.81.1-0.60.61.1-0.8-0.9
Latency to leave start box in cocaine runway, F0.10.10.2-0.30.30.4-0.20.20.2-0.2-0.1
Latency to leave start box in cocaine runway, M1.00.92.2-0.90.90.9-0.60.61.5-0.9-1.2
Cd content in liver1.31.43.11.3-1.3-1.81.1-1.1-1.21.0-0.0
Co content in liver0.40.52.0-0.50.5-0.2-0.40.50.6-0.7-1.4
Cu content in liver0.20.20.4-0.60.60.1-0.60.60.3-0.6-0.4
Fe content in liver0.70.91.11.0-1.0-0.81.0-1.0-0.91.00.8
K content in liver1.21.21.9-1.21.21.4-1.01.01.1-1.1-0.5
Mg content in liver0.60.62.30.5-0.5-0.40.6-0.6-0.50.81.5
Mn content in liver0.10.10.5-0.20.2-0.1-0.40.3-0.1-0.3-0.7
Na content in liver3.33.55.3-2.02.02.3-1.81.82.1-1.9-0.9
Rb content in liver0.40.50.9-0.90.90.6-0.90.90.2-0.9-0.2
Se content in liver0.70.81.40.9-0.9-0.91.1-1.2-0.80.90.1
Sr content in liver0.10.10.10.3-0.3-0.20.2-0.2-0.30.2-0.0
Zn content in liver0.80.81.30.9-0.9-0.90.8-0.7-1.11.00.8