| # | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | isoform ratio | ENSRNOT00000012317 | 0.0180 | 0.0160 | 9.1e-03 | 0.014 | 0.010 | 0.007 | 0.009 | 1.0e-02 | 0.02600 | 0.04400 | 0.03200 |
| 2 | Adipose | isoform ratio | ENSRNOT00000114773 | 0.0180 | 0.0160 | 8.3e-03 | 0.015 | 0.011 | 0.008 | 0.010 | 8.1e-03 | 0.02000 | 0.03500 | 0.02300 |
| 3 | BLA | isoform ratio | ENSRNOT00000012317 | 0.0350 | 0.0300 | 9.3e-03 | 0.038 | -0.001 | 0.010 | 0.013 | 4.1e-03 | 0.38000 | 0.09000 | 0.06500 |
| 4 | BLA | isoform ratio | ENSRNOT00000114773 | 0.0370 | 0.0320 | 7.3e-03 | 0.005 | 0.000 | 0.005 | 0.001 | 1.5e-01 | 0.32000 | 0.16000 | 0.27000 |
| 5 | BLA | mRNA stability | ENSRNOG00000009028 | 0.1500 | 0.1000 | 1.8e-04 | 0.076 | 0.065 | 0.038 | 0.072 | 6.7e-05 | 0.00023 | 0.00430 | 0.00010 |
| 6 | Brain | isoform ratio | ENSRNOT00000012317 | 0.0578 | 0.0416 | 4.2e-05 | 0.042 | 0.039 | 0.038 | 0.037 | 9.3e-05 | 0.00016 | 0.00018 | 0.00022 |
| 7 | Brain | isoform ratio | ENSRNOT00000114773 | 0.0597 | 0.0434 | 5.1e-05 | 0.042 | 0.038 | 0.038 | 0.037 | 9.1e-05 | 0.00017 | 0.00019 | 0.00021 |
| 8 | Liver | isoform ratio | ENSRNOT00000012317 | 0.0293 | 0.0237 | 6.6e-04 | 0.024 | 0.020 | 0.014 | 0.019 | 9.6e-04 | 0.00240 | 0.01000 | 0.00290 |
| 9 | Liver | isoform ratio | ENSRNOT00000114773 | 0.0278 | 0.0229 | 1.2e-03 | 0.020 | 0.015 | 0.010 | 0.014 | 2.5e-03 | 0.00690 | 0.02600 | 0.00870 |
| 10 | Liver | intron excision ratio | chr7:9943967:9944114 | 0.0450 | 0.0375 | 1.5e-03 | 0.019 | 0.007 | 0.009 | 0.011 | 3.1e-03 | 0.05300 | 0.03400 | 0.01700 |
| 11 | Liver | intron excision ratio | chr7:9944012:9944114 | 0.0504 | 0.0407 | 5.1e-04 | 0.023 | 0.009 | 0.011 | 0.014 | 1.1e-03 | 0.02900 | 0.02100 | 0.00900 |
| 12 | PL | isoform ratio | ENSRNOT00000012317 | 0.0280 | 0.0240 | 3.9e-03 | 0.028 | 0.021 | 0.003 | 0.021 | 3.0e-03 | 0.00860 | 0.18000 | 0.00960 |
| 13 | PL | isoform ratio | ENSRNOT00000114773 | 0.0290 | 0.0240 | 3.6e-03 | 0.028 | 0.021 | 0.000 | 0.021 | 3.3e-03 | 0.00930 | 0.35000 | 0.00960 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
| Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 |
|---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Soleus weight | 7.9 | 22.9 | 28.0 | 5.2 | -5.1 | 0.0 | 0.0 | -5.3 | 5.3 | -5.3 | 5.1 | -5.1 | -5.3 | 5.3 | 5.1 | -5.1 |
| Stereotopy head waving duration, day 3 | 6.0 | 7.2 | 8.7 | -2.7 | 2.9 | 0.0 | 0.0 | 3.0 | -3.0 | 3.0 | -2.9 | 2.9 | 3.0 | -3.0 | -2.9 | 2.9 |
| Cocaine response after cond. not corrected | 5.9 | 6.6 | 11.3 | 2.1 | -2.2 | 0.0 | 0.0 | -3.4 | 3.4 | -3.4 | 2.2 | -2.2 | -3.4 | 3.4 | 2.2 | -2.2 |
| Locomotion velocity, session 3 | 5.9 | 6.9 | 9.9 | -2.8 | 3.1 | 0.0 | 0.0 | 2.5 | -2.5 | 2.5 | -3.1 | 3.1 | 2.5 | -2.5 | -3.1 | 3.1 |
| Social responses | 5.7 | 7.3 | 9.8 | -2.6 | 2.8 | 0.0 | 0.0 | 3.1 | -3.1 | 3.1 | -2.8 | 2.8 | 3.1 | -3.1 | -2.8 | 2.8 |
| Cocaine response after cond. corrected | 5.7 | 6.4 | 10.7 | 2.1 | -2.3 | 0.0 | 0.0 | -3.3 | 3.3 | -3.3 | 2.3 | -2.3 | -3.3 | 3.3 | 2.3 | -2.3 |
| BMI with tail | 5.5 | 17.9 | 22.2 | 4.5 | -4.5 | 0.0 | 0.0 | -4.7 | 4.7 | -4.7 | 4.5 | -4.5 | -4.7 | 4.7 | 4.5 | -4.5 |
| Intermittent access intake escalation 2 | 5.5 | 5.5 | 8.7 | -2.9 | 2.9 | 0.0 | 0.0 | 2.0 | -2.0 | 2.0 | -2.9 | 2.9 | 2.0 | -2.0 | -2.9 | 2.9 |
| Conditioned locomotion | 5.4 | 6.5 | 8.3 | -2.9 | 2.8 | 0.0 | 0.0 | 2.8 | -2.8 | 2.8 | -2.8 | 2.8 | 2.8 | -2.8 | -2.7 | 2.7 |
| Stereotopy head waving bouts, day 3 | 5.4 | 6.5 | 8.3 | -2.4 | 2.7 | 0.0 | 0.0 | 2.9 | -2.9 | 2.9 | -2.7 | 2.7 | 2.9 | -2.9 | -2.7 | 2.7 |
| Light reinforcement 1 | 5.3 | 9.7 | 13.9 | -3.2 | 3.0 | 0.0 | 0.0 | 3.7 | -3.7 | 3.7 | -3.0 | 3.0 | 3.7 | -3.7 | -3.1 | 3.1 |
| Intermittent access intake day 1-15 change | 5.3 | 5.3 | 7.6 | -2.6 | 2.8 | 0.0 | 0.0 | 2.2 | -2.2 | 2.2 | -2.8 | 2.8 | 2.2 | -2.2 | -2.7 | 2.7 |
| Delay disc. indifference point, 0s delay | 5.3 | 5.8 | 10.2 | 3.2 | -3.2 | 0.0 | 0.0 | -1.7 | 1.7 | -1.7 | 3.2 | -3.2 | -1.7 | 1.7 | 3.1 | -3.1 |
| Time in familiar zone, hab. session 2 | 4.8 | 5.0 | 8.6 | -2.9 | 2.6 | 0.0 | 0.0 | 2.1 | -2.1 | 2.1 | -2.6 | 2.6 | 2.1 | -2.1 | -2.6 | 2.6 |
| Intermittent access intake escalation | 4.7 | 4.6 | 7.8 | -2.7 | 2.8 | 0.0 | 0.0 | 1.7 | -1.7 | 1.7 | -2.8 | 2.8 | 1.7 | -1.7 | -2.7 | 2.7 |
| Locomotion velocity, session 2 | 4.5 | 5.3 | 8.8 | -1.7 | 2.1 | 0.0 | 0.0 | 3.0 | -3.0 | 3.0 | -2.1 | 2.1 | 3.0 | -3.0 | -2.1 | 2.1 |
| Breakpoint value in progressive ratio session | 4.3 | 4.8 | 7.0 | -2.7 | 2.6 | 0.0 | 0.0 | 2.1 | -2.1 | 2.1 | -2.6 | 2.6 | 2.1 | -2.1 | -2.5 | 2.5 |
| Delay disc. indifference point, 2s delay | 4.3 | 4.8 | 7.4 | 2.7 | -2.6 | 0.0 | 0.0 | -2.1 | 2.1 | -2.1 | 2.6 | -2.6 | -2.1 | 2.1 | 2.5 | -2.5 |
| Condit. Reinf. active minus inactive responses | 4.2 | 4.7 | 6.1 | -2.3 | 2.5 | 0.0 | 0.0 | 2.3 | -2.3 | 2.3 | -2.5 | 2.5 | 2.3 | -2.3 | -2.5 | 2.5 |
| Condit. Reinf. active responses | 4.1 | 4.9 | 7.4 | -2.0 | 2.2 | 0.0 | 0.0 | 2.7 | -2.7 | 2.7 | -2.2 | 2.2 | 2.7 | -2.7 | -2.2 | 2.2 |
| Extensor digitorum longus weight | 3.8 | 15.4 | 24.0 | 4.1 | -3.6 | 0.0 | 0.0 | -4.9 | 4.9 | -4.9 | 3.6 | -3.6 | -4.9 | 4.9 | 3.6 | -3.6 |
| Seeking ratio, delayed vs. immediate footshock | 3.8 | 4.3 | 5.8 | -2.1 | 2.1 | 0.0 | 0.0 | 2.4 | -2.4 | 2.4 | -2.1 | 2.1 | 2.4 | -2.4 | -2.1 | 2.1 |
| Time in novel zone, hab. session 2 | 3.7 | 3.8 | 6.2 | 2.5 | -2.3 | 0.0 | 0.0 | -1.8 | 1.8 | -1.8 | 2.3 | -2.3 | -1.8 | 1.8 | 2.3 | -2.3 |
| Mean time between licks in bursts | 3.5 | 4.8 | 6.5 | -2.6 | 2.5 | 0.0 | 0.0 | 2.2 | -2.2 | 2.2 | -2.5 | 2.5 | 2.2 | -2.2 | -2.5 | 2.5 |
| Novel to familiar place preference ratio | 3.3 | 3.5 | 5.8 | 2.4 | -2.4 | 0.0 | 0.0 | -1.5 | 1.5 | -1.5 | 2.4 | -2.4 | -1.5 | 1.5 | 2.4 | -2.4 |
| Pavlov. Cond. magazine entry latency | 3.3 | 4.3 | 6.4 | -2.1 | 2.5 | 0.0 | 0.0 | 2.0 | -2.0 | 2.0 | -2.5 | 2.5 | 2.0 | -2.0 | -2.5 | 2.5 |
| Intermittent access day 15 total locomotion | 3.0 | 3.2 | 4.3 | -2.1 | 2.1 | 0.0 | 0.0 | 1.8 | -1.8 | 1.8 | -2.1 | 2.1 | 1.8 | -1.8 | -2.0 | 2.0 |
| Short access day 10 total locomotion | 2.9 | 3.2 | 4.7 | -2.1 | 2.2 | 0.0 | 0.0 | 1.7 | -1.7 | 1.7 | -2.2 | 2.2 | 1.7 | -1.7 | -2.1 | 2.1 |
| Locomotor activity | 2.7 | 4.2 | 6.7 | -1.7 | 1.9 | 0.0 | 0.0 | 2.6 | -2.6 | 2.6 | -1.9 | 1.9 | 2.6 | -2.6 | -1.9 | 1.9 |
| Incentive salience index mean | 2.6 | 3.1 | 4.3 | -1.5 | 1.8 | 0.0 | 0.0 | 2.1 | -2.1 | 2.1 | -1.8 | 1.8 | 2.1 | -2.1 | -1.8 | 1.8 |
| Delay discount hyperbolic model param | 2.6 | 2.8 | 3.5 | -1.9 | 1.8 | 0.0 | 0.0 | 1.8 | -1.8 | 1.8 | -1.8 | 1.8 | 1.8 | -1.8 | -1.8 | 1.8 |
| Tail length | 2.5 | 7.5 | 11.4 | -3.1 | 3.4 | 0.0 | 0.0 | 2.5 | -2.5 | 2.5 | -3.4 | 3.4 | 2.5 | -2.5 | -3.4 | 3.4 |
| BMI without tail | 2.3 | 4.7 | 8.5 | 2.0 | -1.8 | 0.0 | 0.0 | -2.9 | 2.9 | -2.9 | 1.8 | -1.8 | -2.9 | 2.9 | 1.7 | -1.7 |
| Locomotion velocity, hab. session 1 | 2.2 | 3.1 | 5.7 | -1.0 | 1.5 | 0.0 | 0.0 | 2.4 | -2.4 | 2.4 | -1.5 | 1.5 | 2.4 | -2.4 | -1.5 | 1.5 |
| Time in novel zone, NPP test | 2.2 | 2.3 | 4.0 | 2.0 | -1.9 | 0.0 | 0.0 | -1.2 | 1.2 | -1.2 | 1.9 | -1.9 | -1.2 | 1.2 | 1.9 | -1.9 |
| Area under the delay curve | 2.1 | 2.2 | 2.7 | 1.6 | -1.6 | 0.0 | 0.0 | -1.6 | 1.6 | -1.6 | 1.6 | -1.6 | -1.6 | 1.6 | 1.6 | -1.6 |
| Locomotion distance, session 2 | 2.0 | 2.9 | 6.6 | -0.9 | 0.8 | 0.0 | 0.0 | 2.6 | -2.6 | 2.6 | -0.8 | 0.8 | 2.6 | -2.6 | -0.8 | 0.8 |
| Novelty place preference | 2.0 | 2.1 | 3.7 | 1.9 | -1.9 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 1.9 | -1.9 | -1.0 | 1.0 | 1.9 | -1.9 |
| Bone: stiffness | 2.0 | 3.2 | 5.4 | 2.3 | -1.8 | 0.0 | 0.0 | -2.0 | 2.0 | -2.0 | 1.8 | -1.8 | -2.0 | 2.0 | 1.8 | -1.8 |
| Light reinforcement 2 | 1.9 | 2.5 | 4.1 | -1.7 | 1.4 | 0.0 | 0.0 | 2.0 | -2.0 | 2.0 | -1.4 | 1.4 | 2.0 | -2.0 | -1.3 | 1.3 |
| Intermittent access standard deviation | 1.9 | 2.0 | 3.4 | -1.8 | 1.8 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -1.8 | 1.8 | 1.2 | -1.2 | -1.8 | 1.8 |
| Delay discount exponential model param | 1.9 | 2.1 | 2.5 | -1.6 | 1.5 | 0.0 | 0.0 | 1.6 | -1.6 | 1.6 | -1.5 | 1.5 | 1.6 | -1.6 | -1.6 | 1.6 |
| Latency to leave start box in cocaine runway, M | 1.9 | 1.9 | 3.5 | -1.9 | 1.8 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -1.8 | 1.8 | 1.0 | -1.0 | -1.8 | 1.8 |
| Liver weight, left | 1.8 | 3.0 | 4.1 | 1.8 | -1.7 | 0.0 | 0.0 | -2.0 | 2.0 | -2.0 | 1.7 | -1.7 | -2.0 | 2.0 | 1.7 | -1.7 |
| Active lever presses in extinction session 6 | 1.8 | 1.8 | 2.7 | -1.5 | 1.2 | 0.0 | 0.0 | 1.6 | -1.6 | 1.6 | -1.2 | 1.2 | 1.6 | -1.6 | -1.2 | 1.2 |
| Delta ambulatory time before/after self-admin | 1.8 | 2.0 | 2.5 | -1.4 | 1.6 | 0.0 | 0.0 | 1.5 | -1.5 | 1.5 | -1.6 | 1.6 | 1.5 | -1.5 | -1.6 | 1.6 |
| Diff in mean of infusions in LGA sessions | 1.7 | 1.9 | 2.4 | -1.6 | 1.5 | 0.0 | 0.0 | 1.5 | -1.5 | 1.5 | -1.5 | 1.5 | 1.5 | -1.5 | -1.4 | 1.4 |
| Time >=10cm from walls, locomotor time 2 | 1.7 | 1.9 | 2.8 | 1.4 | -1.2 | 0.0 | 0.0 | -1.7 | 1.7 | -1.7 | 1.2 | -1.2 | -1.7 | 1.7 | 1.3 | -1.3 |
| Time in familiar zone, hab. session 1 | 1.6 | 1.5 | 2.8 | -1.7 | 1.5 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -1.5 | 1.5 | 1.0 | -1.0 | -1.5 | 1.5 |
| Total locomotion distance, hab. session 1 | 1.6 | 2.3 | 4.6 | -0.7 | 1.2 | 0.0 | 0.0 | 2.1 | -2.1 | 2.1 | -1.2 | 1.2 | 2.1 | -2.1 | -1.2 | 1.2 |
| Locomotion velocity, hab. session 2 | 1.6 | 2.2 | 5.0 | -0.7 | 0.8 | 0.0 | 0.0 | 2.2 | -2.2 | 2.2 | -0.8 | 0.8 | 2.2 | -2.2 | -0.8 | 0.8 |
| Delta distance traveled before/after self-admin | 1.6 | 1.7 | 2.2 | -1.4 | 1.5 | 0.0 | 0.0 | 1.4 | -1.4 | 1.4 | -1.5 | 1.5 | 1.4 | -1.4 | -1.5 | 1.5 |
| Total heroin consumption | 1.6 | 1.9 | 2.4 | -1.5 | 1.4 | 0.0 | 0.0 | 1.6 | -1.6 | 1.6 | -1.4 | 1.4 | 1.6 | -1.6 | -1.4 | 1.4 |
| Run reversals in cocaine runway, males | 1.6 | 1.5 | 2.2 | -1.2 | 1.2 | 0.0 | 0.0 | 1.5 | -1.5 | 1.5 | -1.2 | 1.2 | 1.5 | -1.5 | -1.2 | 1.2 |
| Length with tail | 1.5 | 5.5 | 6.7 | -2.3 | 2.5 | 0.0 | 0.0 | 2.6 | -2.6 | 2.6 | -2.5 | 2.5 | 2.6 | -2.6 | -2.6 | 2.6 |
| Delay discounting water rate 12 sec | 1.5 | 2.3 | 4.9 | 0.9 | -1.0 | 0.0 | 0.0 | -2.2 | 2.2 | -2.2 | 1.0 | -1.0 | -2.2 | 2.2 | 0.9 | -0.9 |
| Locomotor testing distance | 1.5 | 2.4 | 3.9 | -1.4 | 1.4 | 0.0 | 0.0 | 2.0 | -2.0 | 2.0 | -1.4 | 1.4 | 2.0 | -2.0 | -1.4 | 1.4 |
| Conditioned locomotion | 1.5 | 1.8 | 3.6 | 1.0 | -1.0 | 0.0 | 0.0 | -1.9 | 1.9 | -1.9 | 1.0 | -1.0 | -1.9 | 1.9 | 1.0 | -1.0 |
| Condit. Reinf. lever presses | 1.5 | 2.0 | 3.7 | -1.9 | 1.7 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -1.7 | 1.7 | 1.2 | -1.2 | -1.7 | 1.7 |
| Conditioned reinforcement - actives | 1.5 | 1.5 | 2.0 | -1.4 | 1.4 | 0.0 | 0.0 | 1.4 | -1.4 | 1.4 | -1.4 | 1.4 | 1.4 | -1.4 | -1.2 | 1.2 |
| Condit. Reinf. active-inactive response ratio | 1.5 | 1.7 | 2.9 | -1.7 | 1.5 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -1.5 | 1.5 | 1.2 | -1.2 | -1.5 | 1.5 |
| Total locomotion distance, hab. session 2 | 1.5 | 2.0 | 4.2 | -0.8 | 0.9 | 0.0 | 0.0 | 2.0 | -2.0 | 2.0 | -0.9 | 0.9 | 2.0 | -2.0 | -0.9 | 0.9 |
| Pavlov. Cond. response bias | 1.5 | 1.9 | 2.9 | -1.2 | 1.7 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -1.7 | 1.7 | 1.3 | -1.3 | -1.7 | 1.7 |
| Bone: tissue strength | 1.5 | 1.4 | 2.2 | 1.5 | -1.5 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 1.5 | -1.5 | -1.0 | 1.0 | 1.5 | -1.5 |
| Delay disc. indifference point, 8s delay | 1.5 | 1.5 | 2.6 | 1.1 | -1.0 | 0.0 | 0.0 | -1.6 | 1.6 | -1.6 | 1.0 | -1.0 | -1.6 | 1.6 | 1.0 | -1.0 |
| Fecal boli incidents, locomotor time 1 | 1.5 | 1.7 | 2.5 | 1.4 | -1.2 | 0.0 | 0.0 | -1.6 | 1.6 | -1.6 | 1.2 | -1.2 | -1.6 | 1.6 | 1.2 | -1.2 |
| Intermittent access day 15 total infusions | 1.4 | 1.5 | 2.6 | -1.6 | 1.6 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -1.6 | 1.6 | 1.0 | -1.0 | -1.5 | 1.5 |
| Degree of sensitization stereotypy | 1.4 | 1.5 | 2.5 | 1.5 | -1.6 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 1.6 | -1.6 | -1.0 | 1.0 | 1.6 | -1.6 |
| Delta time in closed arm before/after self-admin | 1.4 | 1.3 | 3.2 | 0.4 | -0.4 | 0.0 | 0.0 | -1.8 | 1.8 | -1.8 | 0.4 | -0.4 | -1.8 | 1.8 | 0.5 | -0.5 |
| Mn content in liver | 1.4 | 1.7 | 3.3 | -0.4 | 1.0 | 0.0 | 0.0 | 1.8 | -1.8 | 1.8 | -1.0 | 1.0 | 1.8 | -1.8 | -1.0 | 1.0 |
| Glucose | 1.3 | 2.0 | 2.6 | 1.4 | -1.6 | 0.0 | 0.0 | -1.5 | 1.5 | -1.5 | 1.6 | -1.6 | -1.5 | 1.5 | 1.6 | -1.6 |
| Condit. Reinf. active minus inactive responses | 1.3 | 1.6 | 3.3 | -1.8 | 1.6 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -1.6 | 1.6 | 1.0 | -1.0 | -1.6 | 1.6 |
| Condit. Reinf. active responses | 1.3 | 1.8 | 3.0 | -1.7 | 1.7 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -1.7 | 1.7 | 1.2 | -1.2 | -1.7 | 1.7 |
| Condit. Reinf. inactive responses | 1.3 | 1.6 | 3.3 | -0.7 | 0.8 | 0.0 | 0.0 | 1.8 | -1.8 | 1.8 | -0.8 | 0.8 | 1.8 | -1.8 | -0.8 | 0.8 |
| Pavlov. Cond. lever-magazine prob. diff. | 1.3 | 1.6 | 2.2 | -0.9 | 1.5 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -1.5 | 1.5 | 1.3 | -1.3 | -1.5 | 1.5 |
| Total zone transitions, hab. session 1 | 1.2 | 1.7 | 3.4 | -0.8 | 1.0 | 0.0 | 0.0 | 1.8 | -1.8 | 1.8 | -1.0 | 1.0 | 1.8 | -1.8 | -1.0 | 1.0 |
| Right kidney weight | 1.1 | 3.1 | 3.9 | -1.8 | 1.9 | 0.0 | 0.0 | 1.9 | -1.9 | 1.9 | -1.9 | 1.9 | 1.9 | -1.9 | -2.0 | 2.0 |
| Liver weight, right | 1.1 | 1.8 | 3.0 | 1.7 | -1.4 | 0.0 | 0.0 | -1.4 | 1.4 | -1.4 | 1.4 | -1.4 | -1.4 | 1.4 | 1.4 | -1.4 |
| Delay discounting water rate 24 sec | 1.1 | 1.5 | 3.8 | -0.0 | -0.1 | 0.0 | 0.0 | -2.0 | 2.0 | -2.0 | 0.1 | -0.1 | -2.0 | 2.0 | 0.1 | -0.1 |
| Compulsive drug intake | 1.1 | 1.1 | 1.9 | 1.4 | -1.4 | 0.0 | 0.0 | -0.8 | 0.8 | -0.8 | 1.4 | -1.4 | -0.8 | 0.8 | 1.3 | -1.3 |
| Locomotion velocity, session 8 | 1.1 | 1.4 | 2.6 | -0.4 | 1.0 | 0.0 | 0.0 | 1.6 | -1.6 | 1.6 | -1.0 | 1.0 | 1.6 | -1.6 | -1.0 | 1.0 |
| Pavlov. Cond. magazine entry number | 1.1 | 1.4 | 2.1 | 1.0 | -1.4 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | 1.4 | -1.4 | -1.1 | 1.1 | 1.4 | -1.4 |
| Bone: trabecular tissue density | 1.1 | 1.6 | 2.4 | 1.4 | -1.1 | 0.0 | 0.0 | -1.6 | 1.6 | -1.6 | 1.1 | -1.1 | -1.6 | 1.6 | 1.1 | -1.1 |
| Zn content in liver | 1.1 | 1.2 | 3.0 | -1.7 | 1.5 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -1.5 | 1.5 | 0.5 | -0.5 | -1.5 | 1.5 |
| Body weight | 1.0 | 4.3 | 5.9 | 2.2 | -2.1 | 0.0 | 0.0 | -2.4 | 2.4 | -2.4 | 2.1 | -2.1 | -2.4 | 2.4 | 2.1 | -2.1 |
| Condit. Reinf. inactive responses | 1.0 | 1.2 | 2.2 | -1.1 | 1.5 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -1.5 | 1.5 | 0.9 | -0.9 | -1.5 | 1.5 |
| Pavlov. Cond. response bias | 1.0 | 1.4 | 2.5 | -1.6 | 1.5 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -1.5 | 1.5 | 0.9 | -0.9 | -1.5 | 1.5 |
| Bone: trabecular spacing | 1.0 | 1.2 | 3.2 | 0.2 | -0.1 | 0.0 | 0.0 | -1.8 | 1.8 | -1.8 | 0.1 | -0.1 | -1.8 | 1.8 | 0.1 | -0.1 |
| Delta time in open arm before/after self-admin | 1.0 | 1.0 | 1.8 | 1.2 | -1.3 | 0.0 | 0.0 | -0.8 | 0.8 | -0.8 | 1.3 | -1.3 | -0.8 | 0.8 | 1.2 | -1.2 |
| Vertical activity count, locomotor time 2 | 1.0 | 1.1 | 2.1 | 0.7 | -0.8 | 0.0 | 0.0 | -1.5 | 1.5 | -1.5 | 0.8 | -0.8 | -1.5 | 1.5 | 0.6 | -0.6 |
| Tibialis anterior weight | 0.9 | 3.0 | 4.4 | 2.0 | -1.6 | 0.0 | 0.0 | -2.1 | 2.1 | -2.1 | 1.6 | -1.6 | -2.1 | 2.1 | 1.6 | -1.6 |
| Delay discounting total patch changes 18 sec | 0.9 | 1.2 | 1.5 | -1.2 | 1.2 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -1.2 | 1.2 | 1.2 | -1.2 | -1.1 | 1.1 |
| Social response proportion | 0.9 | 0.9 | 1.9 | -0.7 | 0.7 | 0.0 | 0.0 | 1.4 | -1.4 | 1.4 | -0.7 | 0.7 | 1.4 | -1.4 | -0.7 | 0.7 |
| Condit. Reinf. lever reinforcers received | 0.9 | 1.3 | 2.4 | -1.6 | 1.5 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -1.5 | 1.5 | 0.8 | -0.8 | -1.5 | 1.5 |
| Short access day 1 locomotion | 0.9 | 0.9 | 1.4 | -0.9 | 0.9 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -0.9 | 0.9 | 1.2 | -1.2 | -0.9 | 0.9 |
| Pavlov. Cond. index score | 0.9 | 1.1 | 1.6 | -0.6 | 1.3 | 0.0 | 0.0 | 1.1 | -1.1 | 1.1 | -1.3 | 1.3 | 1.1 | -1.1 | -1.3 | 1.3 |
| Pavlov. Cond. latency score | 0.9 | 1.1 | 1.5 | -0.5 | 1.2 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -1.2 | 1.2 | 1.2 | -1.2 | -1.2 | 1.2 |
| Bone: cortical apparent density | 0.9 | 1.2 | 1.9 | 1.1 | -1.4 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 1.4 | -1.4 | -1.0 | 1.0 | 1.4 | -1.4 |
| Bone: cortical thickness | 0.9 | 1.6 | 2.5 | 1.6 | -1.5 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | 1.5 | -1.5 | -1.1 | 1.1 | 1.5 | -1.5 |
| Bone: final force | 0.9 | 1.5 | 3.0 | 1.7 | -1.4 | 0.0 | 0.0 | -1.2 | 1.2 | -1.2 | 1.4 | -1.4 | -1.2 | 1.2 | 1.4 | -1.4 |
| Bone: maximum force | 0.9 | 1.6 | 2.8 | 1.7 | -1.3 | 0.0 | 0.0 | -1.3 | 1.3 | -1.3 | 1.3 | -1.3 | -1.3 | 1.3 | 1.3 | -1.3 |
| Bone: trabecular thickness | 0.9 | 1.1 | 1.4 | 1.0 | -1.1 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | 1.1 | -1.1 | 1.2 | -1.2 | 1.1 | -1.1 |
| Delay disc. indifference point, 24s delay | 0.9 | 0.9 | 1.2 | 0.8 | -1.0 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | 1.0 | -1.0 | -1.1 | 1.1 | 1.1 | -1.1 |
| Distance moved, locomotor task time 1 | 0.9 | 1.0 | 2.5 | 1.1 | -1.5 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | 1.5 | -1.5 | -0.3 | 0.3 | 1.6 | -1.6 |
| Locomotion in novel chamber post-restriction | 0.9 | 1.1 | 2.1 | -1.1 | 1.5 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -1.5 | 1.5 | 0.6 | -0.6 | -1.5 | 1.5 |
| Reaction time number correct | 0.8 | 1.2 | 2.8 | 0.4 | -0.4 | 0.0 | 0.0 | -1.7 | 1.7 | -1.7 | 0.4 | -0.4 | -1.7 | 1.7 | 0.4 | -0.4 |
| Reaction time trials correct on left | 0.8 | 1.2 | 2.8 | 0.4 | -0.4 | 0.0 | 0.0 | -1.7 | 1.7 | -1.7 | 0.4 | -0.4 | -1.7 | 1.7 | 0.4 | -0.4 |
| Reaction time trials on left | 0.8 | 1.1 | 2.7 | 0.5 | -0.4 | 0.0 | 0.0 | -1.6 | 1.6 | -1.6 | 0.4 | -0.4 | -1.6 | 1.6 | 0.4 | -0.4 |
| Reaction time trials completed | 0.8 | 1.1 | 2.7 | 0.5 | -0.4 | 0.0 | 0.0 | -1.6 | 1.6 | -1.6 | 0.4 | -0.4 | -1.6 | 1.6 | 0.4 | -0.4 |
| Reaction time trials AUC | 0.8 | 1.2 | 3.0 | 0.4 | -0.3 | 0.0 | 0.0 | -1.7 | 1.7 | -1.7 | 0.3 | -0.3 | -1.7 | 1.7 | 0.3 | -0.3 |
| Time in novel zone, hab. session 1 | 0.8 | 0.8 | 1.6 | 1.3 | -1.2 | 0.0 | 0.0 | -0.5 | 0.5 | -0.5 | 1.2 | -1.2 | -0.5 | 0.5 | 1.2 | -1.2 |
| Bone surface | 0.8 | 1.4 | 3.4 | 0.4 | -0.5 | 0.0 | 0.0 | 1.8 | -1.8 | 1.8 | 0.5 | -0.5 | 1.8 | -1.8 | 0.5 | -0.5 |
| Extinction: sum of active levers before priming | 0.8 | 0.8 | 1.5 | -1.2 | 1.2 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -1.2 | 1.2 | 0.6 | -0.6 | -1.2 | 1.2 |
| Time in open arm after self-admin | 0.8 | 0.8 | 1.1 | 0.9 | -1.0 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 1.0 | -1.0 | -1.0 | 1.0 | 1.0 | -1.0 |
| Tibia length | 0.7 | 1.9 | 2.7 | -1.6 | 1.6 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -1.6 | 1.6 | 1.3 | -1.3 | -1.6 | 1.6 |
| Intermittent access terminal intake (last 3 days) | 0.7 | 0.8 | 1.3 | -1.1 | 1.2 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -1.2 | 1.2 | 0.8 | -0.8 | -1.0 | 1.0 |
| Intermittent access total locomotion | 0.7 | 0.8 | 1.1 | -1.0 | 1.0 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -1.0 | 1.0 | 1.0 | -1.0 | -0.9 | 0.9 |
| Locomotion velocity, session 7 | 0.7 | 0.8 | 1.8 | -0.7 | 1.4 | 0.0 | 0.0 | 0.3 | -0.3 | 0.3 | -1.4 | 1.4 | 0.3 | -0.3 | -1.4 | 1.4 |
| Bone volume | 0.7 | 1.2 | 2.7 | 0.5 | -0.6 | 0.0 | 0.0 | 1.6 | -1.6 | 1.6 | 0.6 | -0.6 | 1.6 | -1.6 | 0.6 | -0.6 |
| Bone: cortical tissue density | 0.7 | 0.9 | 1.4 | 0.8 | -1.2 | 0.0 | 0.0 | -0.8 | 0.8 | -0.8 | 1.2 | -1.2 | -0.8 | 0.8 | 1.2 | -1.2 |
| Bone: final moment | 0.7 | 1.2 | 2.4 | 1.5 | -1.3 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 1.3 | -1.3 | -1.0 | 1.0 | 1.3 | -1.3 |
| Bone: maximum diameter | 0.7 | 1.2 | 2.2 | -0.8 | 1.0 | 0.0 | 0.0 | 1.5 | -1.5 | 1.5 | -1.0 | 1.0 | 1.5 | -1.5 | -1.0 | 1.0 |
| Bone: maximum moment | 0.7 | 1.3 | 2.2 | 1.5 | -1.3 | 0.0 | 0.0 | -1.2 | 1.2 | -1.2 | 1.3 | -1.3 | -1.2 | 1.2 | 1.3 | -1.3 |
| Delay disc. indifference point, 4s delay | 0.7 | 0.8 | 1.2 | 1.0 | -1.0 | 0.0 | 0.0 | -0.8 | 0.8 | -0.8 | 1.0 | -1.0 | -0.8 | 0.8 | 1.1 | -1.1 |
| Time >=10cm from walls, locomotor time 1 | 0.7 | 0.7 | 1.5 | 1.2 | -1.2 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 1.2 | -1.2 | -0.4 | 0.4 | 1.2 | -1.2 |
| Rest time, locomotor task time 1 | 0.7 | 0.7 | 1.5 | -0.5 | 1.2 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | -1.2 | 1.2 | 0.7 | -0.7 | -1.2 | 1.2 |
| Vertical activity count, locomotor time 1 | 0.7 | 0.7 | 1.0 | 0.3 | -1.0 | 0.0 | 0.0 | -0.9 | 0.9 | -0.9 | 1.0 | -1.0 | -0.9 | 0.9 | 1.0 | -1.0 |
| Bouts of movement, locomotor time 2 | 0.7 | 0.8 | 1.7 | -0.5 | 0.5 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -0.5 | 0.5 | 1.3 | -1.3 | -0.4 | 0.4 |
| Total resting periods, locomotor time 2 | 0.7 | 0.7 | 1.6 | -0.5 | 0.4 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -0.4 | 0.4 | 1.3 | -1.3 | -0.3 | 0.3 |
| Distance moved, locomotor task time 2 | 0.7 | 0.8 | 1.2 | 0.8 | -0.8 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | 0.8 | -0.8 | -1.1 | 1.1 | 0.9 | -0.9 |
| Weight adjusted by age | 0.7 | 0.7 | 1.7 | 0.4 | -0.5 | 0.0 | 0.0 | -1.3 | 1.3 | -1.3 | 0.5 | -0.5 | -1.3 | 1.3 | 0.5 | -0.5 |
| Latency to leave start box in cocaine runway | 0.7 | 0.7 | 1.8 | -0.5 | 0.0 | 0.0 | 0.0 | 1.4 | -1.4 | 1.4 | -0.0 | 0.0 | 1.4 | -1.4 | -0.0 | 0.0 |
| Food consumed during 24 hour testing period | 0.6 | 0.7 | 1.1 | 0.8 | -0.8 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 0.8 | -0.8 | -1.0 | 1.0 | 0.8 | -0.8 |
| Std. dev. time between licks in bursts | 0.6 | 0.7 | 1.0 | -0.8 | 0.9 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -0.9 | 0.9 | 1.0 | -1.0 | -0.9 | 0.9 |
| Delay discounting time to switch 0 sec | 0.6 | 0.9 | 2.7 | 1.6 | -1.3 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | 1.3 | -1.3 | -0.2 | 0.2 | 1.3 | -1.3 |
| Delay discounting water rate 18 sec | 0.6 | 0.8 | 1.6 | -0.8 | 0.7 | 0.0 | 0.0 | -1.3 | 1.3 | -1.3 | -0.7 | 0.7 | -1.3 | 1.3 | -0.7 | 0.7 |
| Reaction time premature initiation rate | 0.6 | 0.8 | 2.0 | -1.4 | 1.1 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -1.1 | 1.1 | 0.8 | -0.8 | -1.0 | 1.0 |
| Pavlov. Cond. magazine entry number | 0.6 | 0.7 | 1.2 | 0.9 | -1.1 | 0.0 | 0.0 | -0.7 | 0.7 | -0.7 | 1.1 | -1.1 | -0.7 | 0.7 | 1.1 | -1.1 |
| Cocaine induced anxiety | 0.6 | 0.7 | 1.6 | -0.4 | 0.4 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -0.4 | 0.4 | 1.3 | -1.3 | -0.4 | 0.4 |
| Post-drug Anxiety | 0.6 | 0.7 | 1.6 | -0.5 | 0.5 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -0.5 | 0.5 | 1.3 | -1.3 | -0.5 | 0.5 |
| Short access total locomotion | 0.6 | 0.7 | 0.9 | -0.8 | 0.9 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -0.9 | 0.9 | 0.9 | -0.9 | -0.9 | 0.9 |
| Locomotion velocity, session 1 | 0.6 | 0.7 | 1.6 | -0.5 | 0.3 | 0.0 | 0.0 | 1.3 | -1.3 | 1.3 | -0.3 | 0.3 | 1.3 | -1.3 | -0.3 | 0.3 |
| Locomotion distance, session 1 | 0.6 | 0.8 | 1.9 | 0.2 | 0.3 | 0.0 | 0.0 | 1.4 | -1.4 | 1.4 | -0.3 | 0.3 | 1.4 | -1.4 | -0.3 | 0.3 |
| Bone: trabecular number | 0.6 | 1.0 | 2.2 | -0.6 | 0.6 | 0.0 | 0.0 | 1.5 | -1.5 | 1.5 | -0.6 | 0.6 | 1.5 | -1.5 | -0.6 | 0.6 |
| Time in open arm before self-admin | 0.6 | 0.6 | 1.0 | -0.9 | 1.0 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -1.0 | 1.0 | 0.6 | -0.6 | -1.0 | 1.0 |
| Delta time to tail flick, vehicle, before/after SA | 0.6 | 0.6 | 1.6 | 0.2 | 0.0 | 0.0 | 0.0 | -1.3 | 1.3 | -1.3 | -0.0 | 0.0 | -1.3 | 1.3 | 0.0 | -0.0 |
| Rest time, locomotor task time 2 | 0.6 | 0.7 | 1.2 | -0.6 | 0.8 | 0.0 | 0.0 | 1.1 | -1.1 | 1.1 | -0.8 | 0.8 | 1.1 | -1.1 | -0.7 | 0.7 |
| Latency to leave start box in cocaine runway, F | 0.6 | 0.6 | 1.2 | 0.7 | -1.1 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | 1.1 | -1.1 | 0.6 | -0.6 | 1.1 | -1.1 |
| Indifference point AUC | 0.5 | 0.6 | 0.9 | -0.9 | 0.8 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.8 | 0.8 | 0.8 | -0.8 | -0.8 | 0.8 |
| Reaction time num false alarms AUC | 0.5 | 0.7 | 1.7 | 0.1 | 0.0 | 0.0 | 0.0 | -1.3 | 1.3 | -1.3 | -0.0 | 0.0 | -1.3 | 1.3 | 0.1 | -0.1 |
| Social time | 0.5 | 0.6 | 1.1 | 0.9 | -1.1 | 0.0 | 0.0 | -0.6 | 0.6 | -0.6 | 1.1 | -1.1 | -0.6 | 0.6 | 1.0 | -1.0 |
| Cocaine response before conditioning | 0.5 | 0.7 | 0.9 | -0.7 | 1.0 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -1.0 | 1.0 | 0.8 | -0.8 | -1.0 | 1.0 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.5 | 0.6 | 1.0 | -0.9 | 1.0 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | -1.0 | 1.0 | 0.7 | -0.7 | -1.0 | 1.0 |
| Conditioned reinforcement - inactives | 0.5 | 0.6 | 1.1 | 0.5 | -0.5 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | 0.5 | -0.5 | -1.1 | 1.1 | 0.6 | -0.6 |
| Bone: cortical porosity | 0.5 | 0.5 | 1.0 | -0.5 | 0.5 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -0.5 | 0.5 | 1.0 | -1.0 | -0.5 | 0.5 |
| Distance traveled before self-admin | 0.5 | 0.5 | 1.0 | 0.9 | -1.0 | 0.0 | 0.0 | -0.5 | 0.5 | -0.5 | 1.0 | -1.0 | -0.5 | 0.5 | 0.9 | -0.9 |
| Distance traveled after self-admin | 0.5 | 0.5 | 0.8 | -0.6 | 0.6 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -0.6 | 0.6 | 0.9 | -0.9 | -0.7 | 0.7 |
| Time in closed arm before self-admin | 0.5 | 0.5 | 1.3 | 1.1 | -1.0 | 0.0 | 0.0 | -0.1 | 0.1 | -0.1 | 1.0 | -1.0 | -0.1 | 0.1 | 1.1 | -1.1 |
| Time to tail flick, vehicle, before self-admin | 0.5 | 0.5 | 1.2 | -0.4 | 0.3 | 0.0 | 0.0 | 1.1 | -1.1 | 1.1 | -0.3 | 0.3 | 1.1 | -1.1 | -0.2 | 0.2 |
| Ambulatory time before self-admin | 0.5 | 0.5 | 1.0 | 0.8 | -1.0 | 0.0 | 0.0 | -0.5 | 0.5 | -0.5 | 1.0 | -1.0 | -0.5 | 0.5 | 0.9 | -0.9 |
| Food seeking constrained by brief footshock | 0.5 | 0.6 | 0.9 | -0.4 | 1.0 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -1.0 | 1.0 | 0.9 | -0.9 | -1.0 | 1.0 |
| Run reversals in cocaine runway, females | 0.5 | 0.5 | 0.6 | -0.6 | 0.8 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.8 | 0.8 | 0.8 | -0.8 | -0.8 | 0.8 |
| Water consumed over 24 hours | 0.4 | 0.5 | 1.1 | 1.0 | -0.9 | 0.0 | 0.0 | -0.6 | 0.6 | -0.6 | 0.9 | -0.9 | -0.6 | 0.6 | 0.9 | -0.9 |
| Delay discounting total patch changes 12 sec | 0.4 | 0.5 | 0.8 | 0.5 | -0.5 | 0.0 | 0.0 | -0.9 | 0.9 | -0.9 | 0.5 | -0.5 | -0.9 | 0.9 | 0.6 | -0.6 |
| Reaction time mean minus median | 0.4 | 0.5 | 1.0 | -0.9 | 1.0 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -1.0 | 1.0 | 0.5 | -0.5 | -1.0 | 1.0 |
| Reaction time num false alarms | 0.4 | 0.5 | 1.3 | 0.1 | 0.0 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | -0.0 | 0.0 | -1.1 | 1.1 | 0.1 | -0.1 |
| Pavlov. Cond. magazine entry latency | 0.4 | 0.4 | 0.7 | -0.7 | 0.9 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.9 | 0.9 | 0.5 | -0.5 | -0.9 | 0.9 |
| Pavlov. Cond. index score | 0.4 | 0.6 | 0.9 | -1.0 | 1.0 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -1.0 | 1.0 | 0.6 | -0.6 | -1.0 | 1.0 |
| Pavlov. Cond. latency score | 0.4 | 0.5 | 0.7 | -0.8 | 0.8 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | -0.8 | 0.8 | 0.7 | -0.7 | -0.8 | 0.8 |
| Intermitt. access day 15 inactive lever presses | 0.4 | 0.4 | 0.8 | -0.8 | 0.9 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.9 | 0.9 | 0.5 | -0.5 | -0.8 | 0.8 |
| Stereotopy head waving duration, day 7 | 0.4 | 0.4 | 1.0 | -0.2 | 0.3 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | -0.3 | 0.3 | 1.0 | -1.0 | -0.3 | 0.3 |
| Condit. Reinf. lever presses | 0.4 | 0.5 | 1.2 | 0.4 | -0.2 | 0.0 | 0.0 | 1.1 | -1.1 | 1.1 | 0.2 | -0.2 | 1.1 | -1.1 | 0.2 | -0.2 |
| Total zone transitions, hab. session 2 | 0.4 | 0.6 | 1.0 | 0.8 | -0.6 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | 0.6 | -0.6 | 1.0 | -1.0 | 0.6 | -0.6 |
| Locomotion velocity, NPP test | 0.4 | 0.5 | 1.3 | 0.1 | 0.0 | 0.0 | 0.0 | 1.2 | -1.2 | 1.2 | -0.0 | 0.0 | 1.2 | -1.2 | -0.0 | 0.0 |
| Bone: apparent density | 0.4 | 0.6 | 0.9 | 0.8 | -1.0 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | 1.0 | -1.0 | 0.8 | -0.8 | 1.0 | -1.0 |
| Bone: connectivity density | 0.4 | 0.6 | 1.2 | 1.0 | -1.1 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | 1.1 | -1.1 | 0.2 | -0.2 | 1.1 | -1.1 |
| Bone: cortical area | 0.4 | 0.6 | 1.6 | 1.3 | -1.0 | 0.0 | 0.0 | -0.6 | 0.6 | -0.6 | 1.0 | -1.0 | -0.6 | 0.6 | 1.0 | -1.0 |
| Bone: post-yield work | 0.4 | 0.5 | 1.2 | 0.9 | -0.3 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | 0.3 | -0.3 | -1.1 | 1.1 | 0.3 | -0.3 |
| Time to tail flick, test, after self-admin | 0.4 | 0.4 | 0.6 | -0.5 | 0.7 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.7 | 0.7 | 0.8 | -0.8 | -0.6 | 0.6 |
| Total resting periods, locomotor time 1 | 0.4 | 0.4 | 0.9 | -0.5 | 0.9 | 0.0 | 0.0 | 0.4 | -0.4 | 0.4 | -0.9 | 0.9 | 0.4 | -0.4 | -0.9 | 0.9 |
| Co content in liver | 0.4 | 0.5 | 1.0 | -0.8 | 0.9 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -0.9 | 0.9 | 0.6 | -0.6 | -1.0 | 1.0 |
| Se content in liver | 0.4 | 0.5 | 1.1 | -0.4 | 1.0 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -1.0 | 1.0 | 0.6 | -0.6 | -0.9 | 0.9 |
| Parametrial fat weight | 0.3 | 0.5 | 1.0 | -0.9 | 0.9 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.9 | 0.9 | 0.5 | -0.5 | -1.0 | 1.0 |
| Times rat made contact with spout | 0.3 | 0.3 | 0.7 | 0.3 | -0.2 | 0.0 | 0.0 | -0.9 | 0.9 | -0.9 | 0.2 | -0.2 | -0.9 | 0.9 | 0.2 | -0.2 |
| Delay discounting water rate 0 sec | 0.3 | 0.5 | 1.2 | -0.4 | 0.5 | 0.0 | 0.0 | -1.1 | 1.1 | -1.1 | -0.5 | 0.5 | -1.1 | 1.1 | -0.4 | 0.4 |
| Delay discounting water rate 6 sec | 0.3 | 0.4 | 0.8 | -0.9 | 0.7 | 0.0 | 0.0 | -0.6 | 0.6 | -0.6 | -0.7 | 0.7 | -0.6 | 0.6 | -0.9 | 0.9 |
| Median of all reaction times | 0.3 | 0.4 | 0.8 | 0.8 | -0.9 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | 0.9 | -0.9 | -0.3 | 0.3 | 0.8 | -0.8 |
| Reaction time premature initiations | 0.3 | 0.5 | 1.6 | -1.3 | 1.0 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | -1.0 | 1.0 | 0.0 | -0.0 | -0.9 | 0.9 |
| Pavlov. Cond. lever latency | 0.3 | 0.5 | 0.8 | 0.9 | -0.8 | 0.0 | 0.0 | -0.6 | 0.6 | -0.6 | 0.8 | -0.8 | -0.6 | 0.6 | 0.8 | -0.8 |
| Pavlov. Cond. change in total contacts | 0.3 | 0.4 | 0.8 | -0.9 | 0.7 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.7 | 0.7 | 0.5 | -0.5 | -0.7 | 0.7 |
| Pavlov. Cond. lever contacts | 0.3 | 0.5 | 1.0 | -1.0 | 0.9 | 0.0 | 0.0 | 0.4 | -0.4 | 0.4 | -0.9 | 0.9 | 0.4 | -0.4 | -0.9 | 0.9 |
| Pavlov. Cond. intertrial magazine entries | 0.3 | 0.4 | 0.9 | 0.4 | -0.4 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 0.4 | -0.4 | -1.0 | 1.0 | 0.4 | -0.4 |
| Intermittent access day 1 locomotion | 0.3 | 0.3 | 0.6 | -0.8 | 0.7 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.7 | 0.7 | 0.5 | -0.5 | -0.7 | 0.7 |
| Locomotion distance, session 7 | 0.3 | 0.4 | 1.0 | 0.2 | 0.0 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | -0.0 | 0.0 | -1.0 | 1.0 | -0.0 | 0.0 |
| Locomotion distance, session 8 | 0.3 | 0.4 | 0.7 | -0.2 | 0.6 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -0.6 | 0.6 | 0.9 | -0.9 | -0.6 | 0.6 |
| Degree of sensitization distance | 0.3 | 0.3 | 0.5 | 0.7 | -0.5 | 0.0 | 0.0 | -0.7 | 0.7 | -0.7 | 0.5 | -0.5 | -0.7 | 0.7 | 0.5 | -0.5 |
| Total zone transitions, NPP test | 0.3 | 0.4 | 1.0 | 0.3 | -0.3 | 0.0 | 0.0 | 1.0 | -1.0 | 1.0 | 0.3 | -0.3 | 1.0 | -1.0 | 0.3 | -0.3 |
| Pavlov. Cond. change in total contacts | 0.3 | 0.3 | 0.6 | -0.1 | 0.8 | 0.0 | 0.0 | 0.4 | -0.4 | 0.4 | -0.8 | 0.8 | 0.4 | -0.4 | -0.8 | 0.8 |
| Pavlov. Cond. lever contacts | 0.3 | 0.3 | 0.6 | 0.2 | 0.5 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.5 | 0.5 | 0.8 | -0.8 | -0.5 | 0.5 |
| Bone: elastic work | 0.3 | 0.4 | 0.8 | 0.7 | -0.9 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 0.9 | -0.9 | -0.4 | 0.4 | 0.9 | -0.9 |
| Bone: endosteal perimeter | 0.3 | 0.5 | 0.8 | -0.5 | 0.7 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -0.7 | 0.7 | 0.9 | -0.9 | -0.7 | 0.7 |
| Time to tail flick, test, before self-admin | 0.3 | 0.3 | 0.7 | -0.2 | 0.2 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.2 | 0.2 | 0.8 | -0.8 | 0.0 | -0.0 |
| Delta time to tail flick, test, before/after SA | 0.3 | 0.2 | 0.7 | -0.6 | 0.7 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | -0.7 | 0.7 | 0.0 | -0.0 | -0.8 | 0.8 |
| Bouts of movement, locomotor time 1 | 0.3 | 0.4 | 0.9 | -0.4 | 0.9 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.9 | 0.9 | 0.2 | -0.2 | -0.9 | 0.9 |
| Seeking ratio, punishment vs. effort | 0.3 | 0.4 | 0.6 | -0.4 | 0.5 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.5 | 0.5 | 0.8 | -0.8 | -0.5 | 0.5 |
| Cd content in liver | 0.3 | 0.3 | 0.5 | 0.7 | -0.7 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 0.7 | -0.7 | -0.4 | 0.4 | 0.7 | -0.7 |
| Na content in liver | 0.3 | 0.4 | 1.8 | 1.4 | -0.7 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 0.7 | -0.7 | -0.4 | 0.4 | 0.7 | -0.7 |
| Epididymis fat weight | 0.2 | 0.5 | 1.0 | -1.0 | 0.9 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | -0.9 | 0.9 | 0.7 | -0.7 | -0.8 | 0.8 |
| Retroperitoneal fat weight | 0.2 | 0.6 | 0.9 | 0.7 | -0.7 | 0.0 | 0.0 | -1.0 | 1.0 | -1.0 | 0.7 | -0.7 | -1.0 | 1.0 | 0.7 | -0.7 |
| Intraocular pressure | 0.2 | 0.2 | 0.5 | -0.5 | -0.0 | 0.0 | 0.0 | -0.7 | 0.7 | -0.7 | 0.0 | -0.0 | -0.7 | 0.7 | 0.0 | -0.0 |
| Number of licking bursts | 0.2 | 0.2 | 0.5 | -0.0 | 0.1 | 0.0 | 0.0 | -0.7 | 0.7 | -0.7 | -0.1 | 0.1 | -0.7 | 0.7 | -0.1 | 0.1 |
| Indifference point function ln k | 0.2 | 0.3 | 0.6 | 0.5 | -0.5 | 0.0 | 0.0 | -0.8 | 0.8 | -0.8 | 0.5 | -0.5 | -0.8 | 0.8 | 0.5 | -0.5 |
| Indifference point function log k | 0.2 | 0.3 | 0.6 | 0.5 | -0.5 | 0.0 | 0.0 | -0.8 | 0.8 | -0.8 | 0.5 | -0.5 | -0.8 | 0.8 | 0.5 | -0.5 |
| Delay discounting total patch changes 6 sec | 0.2 | 0.2 | 0.5 | -0.5 | 0.3 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | -0.3 | 0.3 | 0.7 | -0.7 | -0.2 | 0.2 |
| Reaction time omissions | 0.2 | 0.3 | 0.7 | -0.5 | 0.1 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.1 | 0.1 | 0.8 | -0.8 | -0.2 | 0.2 |
| Intermitt. access escalation Index | 0.2 | 0.2 | 0.4 | 0.6 | -0.6 | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | 0.6 | -0.6 | 0.1 | -0.1 | 0.5 | -0.5 |
| Baseline Anxiety | 0.2 | 0.2 | 0.4 | -0.6 | 0.6 | 0.0 | 0.0 | -0.0 | 0.0 | -0.0 | -0.6 | 0.6 | -0.0 | 0.0 | -0.6 | 0.6 |
| Short access day 1 total infusions | 0.2 | 0.3 | 0.6 | -0.2 | 0.3 | 0.0 | 0.0 | 0.8 | -0.8 | 0.8 | -0.3 | 0.3 | 0.8 | -0.8 | -0.2 | 0.2 |
| Context. condit. distance diff. score | 0.2 | 0.2 | 0.5 | 0.4 | -0.0 | 0.0 | 0.0 | -0.7 | 0.7 | -0.7 | 0.0 | -0.0 | -0.7 | 0.7 | 0.0 | -0.0 |
| Stereotopy head waving bouts, day 7 | 0.2 | 0.2 | 0.4 | 0.0 | 0.1 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | -0.1 | 0.1 | 0.7 | -0.7 | -0.1 | 0.1 |
| Total locomotion distance, NPP test | 0.2 | 0.3 | 0.7 | 0.4 | -0.2 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | 0.2 | -0.2 | 0.9 | -0.9 | 0.2 | -0.2 |
| Bone: cortical porosity | 0.2 | 0.2 | 0.5 | 0.2 | -0.1 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | 0.1 | -0.1 | 0.7 | -0.7 | 0.1 | -0.1 |
| Bone: cortical thickness | 0.2 | 0.2 | 0.5 | -0.2 | 0.1 | 0.0 | 0.0 | -0.7 | 0.7 | -0.7 | -0.1 | 0.1 | -0.7 | 0.7 | -0.1 | 0.1 |
| Bone: periosteal estimation | 0.2 | 0.3 | 1.0 | 1.0 | -0.7 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | 0.7 | -0.7 | -0.3 | 0.3 | 0.7 | -0.7 |
| Time to tail flick, vehicle, after self-admin | 0.2 | 0.2 | 0.5 | -0.6 | 0.7 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | -0.7 | 0.7 | -0.2 | 0.2 | -0.7 | 0.7 |
| Ambulatory time after self-admin | 0.2 | 0.3 | 0.5 | -0.4 | 0.4 | 0.0 | 0.0 | 0.7 | -0.7 | 0.7 | -0.4 | 0.4 | 0.7 | -0.7 | -0.5 | 0.5 |
| Fe content in liver | 0.2 | 0.2 | 0.6 | -0.3 | 0.8 | 0.0 | 0.0 | -0.1 | 0.1 | -0.1 | -0.8 | 0.8 | -0.1 | 0.1 | -0.8 | 0.8 |
| Rb content in liver | 0.2 | 0.3 | 0.9 | 1.0 | -0.8 | 0.0 | 0.0 | -0.0 | 0.0 | -0.0 | 0.8 | -0.8 | -0.0 | 0.0 | 0.8 | -0.8 |
| Heart weight | 0.1 | 0.1 | 0.7 | -0.8 | 0.3 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.3 | 0.3 | 0.2 | -0.2 | -0.4 | 0.4 |
| Length without tail | 0.1 | 0.3 | 0.7 | 0.0 | 0.1 | 0.0 | 0.0 | 0.9 | -0.9 | 0.9 | -0.1 | 0.1 | 0.9 | -0.9 | -0.1 | 0.1 |
| Indifference point 0 sec | 0.1 | 0.2 | 0.4 | 0.5 | -0.6 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | 0.6 | -0.6 | -0.2 | 0.2 | 0.7 | -0.7 |
| Delay discounting total patch changes 0 sec | 0.1 | 0.1 | 0.2 | 0.4 | -0.4 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | 0.4 | -0.4 | -0.3 | 0.3 | 0.5 | -0.5 |
| Delay discounting total patch changes 24 sec | 0.1 | 0.1 | 0.2 | -0.2 | 0.0 | 0.0 | 0.0 | 0.4 | -0.4 | 0.4 | -0.0 | 0.0 | 0.4 | -0.4 | -0.0 | 0.0 |
| Reaction time mean AUC | 0.1 | 0.1 | 0.2 | 0.3 | -0.5 | 0.0 | 0.0 | -0.0 | 0.0 | -0.0 | 0.5 | -0.5 | -0.0 | 0.0 | 0.4 | -0.4 |
| Std. dev. reaction times | 0.1 | 0.1 | 0.2 | -0.4 | 0.4 | 0.0 | 0.0 | 0.3 | -0.3 | 0.3 | -0.4 | 0.4 | 0.3 | -0.3 | -0.4 | 0.4 |
| Condit. Reinf. active-inactive response ratio | 0.1 | 0.1 | 0.2 | -0.5 | -0.1 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | 0.1 | -0.1 | -0.3 | 0.3 | 0.1 | -0.1 |
| Intermitt. access day 1 inactive lever presses | 0.1 | 0.1 | 0.2 | -0.5 | 0.4 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | -0.4 | 0.4 | -0.3 | 0.3 | -0.3 | 0.3 |
| Intermittent access day 1 total infusions | 0.1 | 0.1 | 0.2 | 0.2 | -0.4 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | 0.4 | -0.4 | -0.2 | 0.2 | 0.5 | -0.5 |
| Intermittent access total infusions | 0.1 | 0.1 | 0.3 | -0.5 | 0.5 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.5 | 0.5 | 0.2 | -0.2 | -0.4 | 0.4 |
| Incentive Sensitization - Responses | 0.1 | 0.1 | 0.2 | -0.4 | 0.3 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | -0.3 | 0.3 | -0.2 | 0.2 | -0.2 | 0.2 |
| Incentive Sensitization - Breakpoint | 0.1 | 0.1 | 0.2 | -0.5 | 0.4 | 0.0 | 0.0 | -0.1 | 0.1 | -0.1 | -0.4 | 0.4 | -0.1 | 0.1 | -0.3 | 0.3 |
| Progressive ratio test 1 active lever presses | 0.1 | 0.1 | 0.3 | 0.0 | 0.0 | 0.0 | 0.0 | -0.5 | 0.5 | -0.5 | -0.0 | 0.0 | -0.5 | 0.5 | 0.1 | -0.1 |
| Progressive ratio test 1 breakpoint | 0.1 | 0.1 | 0.4 | 0.1 | -0.0 | 0.0 | 0.0 | -0.6 | 0.6 | -0.6 | 0.0 | -0.0 | -0.6 | 0.6 | 0.1 | -0.1 |
| Progressive ratio test 2 active lever presses | 0.1 | 0.1 | 0.3 | -0.5 | 0.5 | 0.0 | 0.0 | -0.1 | 0.1 | -0.1 | -0.5 | 0.5 | -0.1 | 0.1 | -0.3 | 0.3 |
| Progressive ratio test 2 breakpoint | 0.1 | 0.1 | 0.3 | -0.5 | 0.5 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.5 | 0.5 | 0.2 | -0.2 | -0.3 | 0.3 |
| Short access day 1 total inactive lever presses | 0.1 | 0.1 | 0.1 | -0.3 | 0.3 | 0.0 | 0.0 | 0.3 | -0.3 | 0.3 | -0.3 | 0.3 | 0.3 | -0.3 | -0.1 | 0.1 |
| Short access day 10 total infusions | 0.1 | 0.1 | 0.2 | -0.4 | 0.4 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | -0.4 | 0.4 | -0.2 | 0.2 | -0.3 | 0.3 |
| One hour access (0.3 mA shock) | 0.1 | 0.2 | 0.2 | 0.3 | -0.3 | 0.0 | 0.0 | -0.5 | 0.5 | -0.5 | 0.3 | -0.3 | -0.5 | 0.5 | 0.5 | -0.5 |
| One hour access (shock baseline) | 0.1 | 0.1 | 0.4 | -0.6 | 0.6 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | -0.6 | 0.6 | -0.2 | 0.2 | -0.4 | 0.4 |
| Number of responses in last shaping day | 0.1 | 0.1 | 0.1 | -0.4 | 0.3 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.3 | 0.3 | 0.2 | -0.2 | -0.2 | 0.2 |
| Pavlov. Cond. lever latency | 0.1 | 0.1 | 0.2 | -0.3 | -0.3 | 0.0 | 0.0 | -0.5 | 0.5 | -0.5 | 0.3 | -0.3 | -0.5 | 0.5 | 0.3 | -0.3 |
| Pavlov. Cond. intertrial magazine entries | 0.1 | 0.1 | 0.3 | -0.5 | 0.3 | 0.0 | 0.0 | -0.1 | 0.1 | -0.1 | -0.3 | 0.3 | -0.1 | 0.1 | -0.3 | 0.3 |
| Bone: elastic displacement | 0.1 | 0.1 | 0.3 | -0.4 | 0.0 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -0.0 | 0.0 | 0.6 | -0.6 | -0.0 | 0.0 |
| Bone: endosteal estimation | 0.1 | 0.1 | 0.4 | 0.6 | -0.4 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 0.4 | -0.4 | -0.4 | 0.4 | 0.4 | -0.4 |
| Bone: marrow area | 0.1 | 0.1 | 0.4 | 0.6 | -0.4 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 0.4 | -0.4 | -0.4 | 0.4 | 0.4 | -0.4 |
| Bone: periosteal perimeter | 0.1 | 0.1 | 0.3 | 0.1 | 0.2 | 0.0 | 0.0 | 0.6 | -0.6 | 0.6 | -0.2 | 0.2 | 0.6 | -0.6 | -0.2 | 0.2 |
| Delay disc. indifference point, 16s delay | 0.1 | 0.1 | 0.2 | 0.3 | -0.4 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | 0.4 | -0.4 | -0.3 | 0.3 | 0.5 | -0.5 |
| Change in fecal boli incidents, locomotor task | 0.1 | 0.1 | 0.3 | -0.2 | 0.4 | 0.0 | 0.0 | 0.4 | -0.4 | 0.4 | -0.4 | 0.4 | 0.4 | -0.4 | -0.6 | 0.6 |
| Locomotion in novel chamber | 0.1 | 0.1 | 0.3 | -0.5 | 0.5 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.5 | 0.5 | 0.2 | -0.2 | -0.5 | 0.5 |
| Progressive ratio | 0.1 | 0.1 | 0.2 | 0.3 | -0.1 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 0.1 | -0.1 | -0.4 | 0.4 | 0.1 | -0.1 |
| Cu content in liver | 0.1 | 0.1 | 0.5 | 0.7 | -0.4 | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | 0.4 | -0.4 | 0.1 | -0.1 | 0.4 | -0.4 |
| K content in liver | 0.1 | 0.1 | 0.2 | 0.4 | 0.3 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.3 | 0.3 | 0.5 | -0.5 | -0.2 | 0.2 |
| Mg content in liver | 0.1 | 0.1 | 0.2 | 0.5 | 0.1 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.1 | 0.1 | 0.5 | -0.5 | 0.0 | -0.0 |
| Sr content in liver | 0.1 | 0.1 | 0.2 | -0.3 | 0.2 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | -0.2 | 0.2 | -0.4 | 0.4 | -0.3 | 0.3 |
| Left kidney weight | 0.0 | 0.1 | 0.2 | 0.1 | 0.1 | 0.0 | 0.0 | 0.5 | -0.5 | 0.5 | -0.1 | 0.1 | 0.5 | -0.5 | -0.1 | 0.1 |
| Mean num. licks in bursts | 0.0 | 0.0 | 0.1 | 0.1 | -0.2 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | 0.2 | -0.2 | 0.0 | -0.0 | 0.2 | -0.2 |
| Locomotor testing rearing | 0.0 | 0.1 | 0.1 | -0.2 | 0.2 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | -0.2 | 0.2 | -0.3 | 0.3 | -0.3 | 0.3 |
| Reaction time mean minus median AUC | 0.0 | 0.0 | 0.1 | 0.3 | -0.0 | 0.0 | 0.0 | 0.3 | -0.3 | 0.3 | 0.0 | -0.0 | 0.3 | -0.3 | -0.0 | 0.0 |
| Reaction time mean | 0.0 | 0.0 | 0.1 | 0.2 | -0.3 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | 0.3 | -0.3 | 0.0 | -0.0 | 0.2 | -0.2 |
| Reaction time false alarm rate | 0.0 | 0.1 | 0.1 | 0.1 | -0.0 | 0.0 | 0.0 | -0.4 | 0.4 | -0.4 | 0.0 | -0.0 | -0.4 | 0.4 | 0.2 | -0.2 |
| Saline control response | 0.0 | 0.1 | 0.1 | 0.2 | -0.2 | 0.0 | 0.0 | -0.3 | 0.3 | -0.3 | 0.2 | -0.2 | -0.3 | 0.3 | 0.2 | -0.2 |
| Lifetime Intake | 0.0 | 0.0 | 0.1 | -0.3 | 0.3 | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | -0.3 | 0.3 | 0.1 | -0.1 | -0.2 | 0.2 |
| Progressive ratio test 1 inactive lever presses | 0.0 | 0.0 | 0.0 | -0.2 | 0.2 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.2 | 0.2 | 0.2 | -0.2 | -0.1 | 0.1 |
| Progressive ratio test 2 inactive lever presses | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | 0.0 | 0.0 | 0.2 | -0.2 | 0.2 | -0.1 | 0.1 | 0.2 | -0.2 | 0.0 | -0.0 |
| Total sessions with >9 infusions | 0.0 | 0.0 | 0.1 | 0.3 | -0.2 | 0.0 | 0.0 | -0.0 | 0.0 | -0.0 | 0.2 | -0.2 | -0.0 | 0.0 | 0.3 | -0.3 |
| Short access day 10 total inactive lever presses | 0.0 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | 0.0 | -0.0 | -0.2 | 0.2 | 0.1 | -0.1 |
| Short access total infusions | 0.0 | 0.0 | 0.0 | 0.1 | -0.0 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | 0.0 | -0.0 | 0.0 | -0.0 | 0.0 | -0.0 |
| Locomotion distance, session 3 | 0.0 | 0.0 | 0.1 | -0.1 | 0.3 | 0.0 | 0.0 | -0.2 | 0.2 | -0.2 | -0.3 | 0.3 | -0.2 | 0.2 | -0.3 | 0.3 |
| Bone: minimum diameter | 0.0 | 0.0 | 0.1 | 0.3 | 0.2 | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | -0.2 | 0.2 | 0.1 | -0.1 | -0.2 | 0.2 |
| Time in closed arm after self-admin | 0.0 | 0.0 | 0.1 | -0.2 | 0.2 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | -0.2 | 0.2 | 0.0 | -0.0 | -0.2 | 0.2 |
| Sum of active levers in priming session hrs 5-6 | 0.0 | 0.0 | 0.0 | 0.1 | -0.1 | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 | -0.1 | 0.2 | -0.2 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.