Hub : Genes

Barx2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	ENSRNOG00000008592	0.22	0.13	3.8e-08	0.14	0.12	0.11	0.14	6.2e-08	7.3e-07	2.6e-06	8.0e-08
2	BLA	mRNA stability	ENSRNOG00000008592	0.05	0.04	1.6e-03	0.02	0.04	0.02	0.03	2.1e-02	3.2e-03	3.1e-02	1.4e-02
3	Brain	mRNA stability	ENSRNOG00000008592	0.03	0.02	1.8e-03	0.02	0.01	0.01	0.01	1.1e-02	3.3e-02	3.2e-02	4.8e-02
4	LHb	gene expression	ENSRNOG00000008592	0.13	0.11	7.8e-03	0.03	0.04	0.01	0.04	5.4e-02	4.7e-02	1.9e-01	3.9e-02
5	NAcc	gene expression	ENSRNOG00000008592	0.05	0.03	1.5e-04	0.04	0.03	0.03	0.04	4.3e-04	1.8e-03	2.1e-03	7.7e-04
6	NAcc	mRNA stability	ENSRNOG00000008592	0.05	0.04	3.1e-04	0.02	0.03	0.01	0.02	1.3e-02	1.5e-03	2.6e-02	1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	0.3	1.1	3.6	-0.4	-1.5	0.5	-0.3	-0.5	-1.9
BMI without tail	0.2	0.4	1.0	0.5	-0.2	-0.6	1.0	0.5	-0.8
Body weight	0.1	0.6	1.1	-0.6	-0.9	0.7	-1.0	-0.6	-0.7
Epididymis fat weight	0.2	0.4	1.6	0.1	-0.7	-0.2	-0.0	0.0	-1.3
Glucose	0.1	0.1	0.2	-0.3	0.1	0.2	-0.4	-0.3	0.5
Heart weight	0.7	0.9	3.3	0.4	1.3	-0.3	0.7	0.3	1.8
Left kidney weight	0.1	0.2	0.9	0.2	0.5	-0.3	0.1	0.2	1.0
Right kidney weight	0.5	1.4	2.5	1.1	1.0	-1.2	0.8	1.1	1.6
Tail length	0.2	0.5	1.1	0.4	1.0	-0.5	0.3	0.5	1.0
Length with tail	0.2	0.6	1.7	-0.7	0.0	0.7	-1.3	-0.6	0.7
Length without tail	0.6	1.3	3.5	-1.1	-0.6	1.3	-1.9	-1.1	0.3
Liver weight, left	0.1	0.1	0.3	0.5	0.4	-0.4	0.1	0.5	-0.0
Liver weight, right	0.9	1.5	4.1	-0.9	-1.3	1.1	-0.6	-0.9	-2.0
Parametrial fat weight	0.6	1.2	4.3	-0.2	-1.6	0.3	-0.6	-0.3	-2.1
Retroperitoneal fat weight	0.4	1.5	4.9	-0.5	-1.8	0.3	-0.5	-0.4	-2.2
Intraocular pressure	0.1	0.2	0.4	0.6	0.3	-0.4	0.5	0.5	-0.3
Extensor digitorum longus weight	0.2	0.6	1.8	0.6	1.0	-0.5	0.3	0.5	1.4
Soleus weight	0.0	0.0	0.1	-0.1	-0.4	0.1	0.1	-0.1	-0.2
Tibialis anterior weight	0.2	0.6	1.9	-0.7	-0.2	0.7	-1.4	-0.7	0.5
Tibia length	0.7	2.1	2.4	-1.4	-1.3	1.5	-1.5	-1.5	-1.3
Number of licking bursts	0.1	0.1	0.4	-0.0	-0.4	0.1	-0.1	-0.1	-0.7
Food consumed during 24 hour testing period	0.0	0.0	0.1	-0.3	0.0	0.2	-0.1	-0.2	0.1
Times rat made contact with spout	0.2	0.2	0.5	-0.3	-0.4	0.3	-0.3	-0.4	-0.7
Mean time between licks in bursts	0.5	0.7	2.8	-0.3	-0.9	0.1	-0.5	-0.2	-1.7
Mean num. licks in bursts	0.1	0.1	0.3	0.2	0.5	-0.3	0.3	0.3	0.5
Std. dev. time between licks in bursts	1.1	1.3	1.5	-1.2	-1.2	1.2	-1.2	-1.2	-1.0
Water consumed over 24 hours	1.2	1.4	2.1	-1.4	-0.8	1.3	-1.2	-1.4	-0.6
Indifference point 0 sec	0.1	0.2	0.4	-0.4	-0.3	0.6	-0.6	-0.6	0.1
Indifference point AUC	0.1	0.2	0.3	0.4	-0.4	-0.3	0.4	0.2	-0.6
Indifference point function ln k	0.1	0.1	0.2	-0.4	-0.0	0.4	-0.5	-0.4	0.2
Indifference point function log k	0.1	0.1	0.2	-0.4	-0.0	0.4	-0.5	-0.4	0.2
Delay discounting total patch changes 0 sec	0.1	0.2	0.4	-0.5	-0.3	0.6	-0.6	-0.6	-0.1
Delay discounting total patch changes 12 sec	0.1	0.1	0.2	0.4	-0.0	-0.4	0.4	0.4	-0.1
Delay discounting total patch changes 18 sec	1.0	1.4	2.4	-0.9	-1.6	0.9	-0.9	-1.0	-1.6
Delay discounting total patch changes 24 sec	0.0	0.1	0.2	0.3	-0.1	-0.2	0.4	0.2	-0.2
Delay discounting total patch changes 6 sec	0.4	0.5	0.8	0.8	0.4	-0.9	0.8	0.8	0.5
Delay discounting time to switch 0 sec	0.1	0.1	0.2	0.3	0.3	-0.4	0.3	0.5	0.4
Delay discounting water rate 0 sec	0.4	0.7	1.2	-0.6	-1.0	0.5	-0.8	-0.7	-1.1
Delay discounting water rate 12 sec	0.4	0.6	0.8	-0.8	-0.8	0.9	-0.6	-0.8	-0.9
Delay discounting water rate 18 sec	0.3	0.4	0.6	-0.7	-0.3	0.7	-0.7	-0.8	-0.3
Delay discounting water rate 24 sec	0.6	0.9	1.4	-1.2	-0.8	1.1	-0.5	-1.2	-0.6
Delay discounting water rate 6 sec	1.1	1.6	2.4	-1.1	-1.3	1.2	-0.9	-1.2	-1.5
Locomotor activity	0.1	0.2	0.4	-0.6	-0.3	0.5	-0.3	-0.6	-0.1
Locomotor testing distance	0.2	0.3	0.6	-0.8	-0.2	0.6	-0.4	-0.8	-0.2
Locomotor testing rearing	0.1	0.2	0.4	-0.6	-0.2	0.5	-0.3	-0.7	-0.3
Light reinforcement 1	0.2	0.4	0.5	0.7	0.4	-0.6	0.7	0.6	0.7
Light reinforcement 2	0.3	0.4	0.7	0.7	0.2	-0.8	0.7	0.8	0.0
Reaction time number correct	0.9	1.3	2.2	-1.4	-0.6	1.4	-1.2	-1.5	-0.3
Reaction time mean minus median	0.1	0.1	0.3	-0.3	-0.5	0.2	-0.0	-0.3	0.1
Reaction time mean minus median AUC	1.1	1.4	1.8	1.2	0.8	-1.3	1.3	1.2	1.1
Reaction time num false alarms	2.8	3.8	4.9	-2.0	-2.1	2.1	-1.4	-2.2	-1.7
Reaction time num false alarms AUC	3.0	4.2	5.5	-2.1	-2.1	2.3	-1.7	-2.4	-1.7
Reaction time trials correct on left	0.9	1.3	2.2	-1.4	-0.6	1.4	-1.2	-1.5	-0.3
Reaction time trials on left	0.7	1.1	1.8	-1.3	-0.5	1.3	-1.0	-1.3	-0.3
Reaction time mean	0.4	0.5	1.1	0.8	0.2	-0.8	1.0	0.7	0.3
Reaction time mean AUC	0.3	0.4	0.7	0.7	0.1	-0.7	0.9	0.7	0.2
Median of all reaction times	0.9	1.2	2.0	1.3	0.6	-1.3	1.4	1.2	0.4
Reaction time omissions	5.4	7.2	9.8	3.0	2.2	-3.1	3.0	2.8	1.7
Reaction time false alarm rate	1.9	2.7	3.5	-1.6	-1.9	1.7	-1.2	-1.7	-1.6
Reaction time premature initiation rate	0.5	0.7	1.3	-0.8	-1.1	0.8	0.1	-0.9	-1.0
Reaction time premature initiations	0.7	1.0	1.5	-1.2	-1.0	1.2	-0.2	-1.2	-0.8
Std. dev. reaction times	0.2	0.3	0.6	0.4	0.1	-0.5	0.8	0.4	0.6
Reaction time trials completed	0.7	1.1	1.8	-1.3	-0.5	1.3	-1.0	-1.3	-0.3
Reaction time trials AUC	0.9	1.3	2.1	-1.4	-0.6	1.4	-1.1	-1.5	-0.3
Social response proportion	1.8	2.0	2.5	-1.4	-1.6	1.4	-1.0	-1.5	-1.4
Social responses	0.6	0.8	2.3	-0.7	-1.2	0.6	-0.3	-0.7	-1.5
Social time	0.3	0.4	0.9	0.8	0.4	-0.9	0.6	0.8	0.1
Conditioned locomotion	0.1	0.1	0.2	-0.3	-0.4	0.4	-0.2	-0.3	-0.3
Cocaine response after cond. corrected	0.8	0.9	1.4	-0.9	-1.2	0.9	-0.8	-0.9	-1.2
Cocaine response after cond. not corrected	1.9	2.1	2.8	-1.4	-1.7	1.3	-1.3	-1.3	-1.6
Cocaine response before conditioning	0.2	0.2	0.5	-0.5	-0.3	0.5	-0.7	-0.4	0.1
Saline control response	0.0	0.0	0.1	-0.2	-0.1	0.3	-0.0	-0.3	0.1
Condit. Reinf. active minus inactive responses	0.4	0.5	0.8	-0.9	-0.5	0.9	-0.5	-0.8	-0.2
Condit. Reinf. active-inactive response ratio	0.7	0.7	1.2	0.7	1.0	-0.7	1.1	0.7	1.0
Condit. Reinf. active responses	1.9	2.6	3.5	-1.9	-1.5	1.8	-1.4	-1.8	-1.2
Condit. Reinf. inactive responses	3.5	4.4	5.0	-2.1	-2.2	2.1	-2.0	-2.1	-2.1
Condit. Reinf. lever presses	4.1	5.7	6.8	-2.6	-2.4	2.6	-2.3	-2.6	-1.7
Condit. Reinf. lever reinforcers received	2.0	2.9	3.8	-1.9	-1.6	1.9	-1.5	-1.9	-1.3
Pavlov. Cond. lever latency	7.1	9.7	10.3	3.2	3.2	-3.2	3.0	3.2	2.9
Pavlov. Cond. magazine entry latency	1.8	2.1	2.8	-1.4	-1.6	1.4	-1.7	-1.3	-1.3
Pavlov. Cond. change in total contacts	5.0	6.9	7.6	-2.7	-2.8	2.6	-2.5	-2.6	-2.6
Pavlov. Cond. index score	5.3	6.9	7.6	-2.6	-2.8	2.6	-2.6	-2.6	-2.5
Pavlov. Cond. latency score	4.6	5.9	6.2	-2.5	-2.5	2.5	-2.5	-2.5	-2.1
Pavlov. Cond. lever contacts	7.1	9.9	11.5	-3.1	-3.4	3.1	-3.0	-3.1	-3.1
Pavlov. Cond. magazine entry number	1.8	2.2	2.9	1.5	1.7	-1.4	1.4	1.5	1.4
Pavlov. Cond. intertrial magazine entries	1.2	1.6	2.8	1.1	1.2	-1.2	1.7	1.2	1.0
Pavlov. Cond. lever-magazine prob. diff.	5.9	7.7	8.6	-2.8	-2.9	2.8	-2.7	-2.8	-2.6
Pavlov. Cond. response bias	6.7	9.3	10.8	-3.0	-3.3	3.0	-2.9	-3.0	-3.1
Conditioned reinforcement - actives	0.7	0.6	1.5	-1.0	-0.3	0.8	-0.7	-1.2	0.6
Conditioned reinforcement - inactives	0.4	0.4	1.1	-0.6	-0.4	0.6	-1.1	-0.8	0.1
Conditioned locomotion	1.1	1.3	1.9	-1.3	-1.0	1.2	-1.3	-1.4	-0.3
Intermittent access intake day 1-15 change	0.2	0.2	0.7	-0.4	-0.1	0.4	-0.4	-0.8	0.2
Intermittent access intake escalation	0.3	0.3	0.8	-0.6	-0.2	0.5	-0.5	-0.9	0.1
Intermittent access intake escalation 2	1.4	1.4	3.7	0.9	1.5	-0.9	0.7	0.6	1.9
Intermitt. access day 1 inactive lever presses	0.0	0.1	0.2	0.2	0.2	-0.2	0.4	0.2	0.1
Intermitt. access day 15 inactive lever presses	1.1	1.2	1.7	-1.2	-1.0	1.1	-1.1	-1.3	-0.8
Intermitt. access escalation Index	0.8	0.7	1.2	-0.8	-0.9	0.8	-0.6	-1.1	-0.9
Intermittent access day 1 total infusions	0.3	0.4	0.6	-0.7	-0.6	0.5	-0.6	-0.7	-0.4
Intermittent access day 15 total infusions	0.2	0.2	0.7	-0.5	-0.1	0.4	-0.3	-0.9	0.4
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.4	-0.1	0.2	-0.0	-0.3	-0.5	0.6
Intermittent access total infusions	0.3	0.3	0.7	-0.6	-0.4	0.5	-0.7	-0.8	-0.1
Intermittent access day 1 locomotion	0.1	0.1	0.1	-0.3	-0.2	0.2	-0.3	-0.3	-0.1
Intermittent access day 15 total locomotion	0.0	0.0	0.1	-0.0	0.1	-0.1	0.2	-0.1	0.3
Intermittent access total locomotion	0.1	0.1	0.1	-0.3	-0.1	0.2	-0.2	-0.4	0.3
Intermittent access standard deviation	2.0	2.1	4.3	1.2	1.8	-1.3	1.1	1.0	2.1
Cocaine induced anxiety	2.0	2.3	4.4	-1.4	-1.4	1.6	-2.1	-1.4	-0.9
Post-drug Anxiety	1.2	1.4	1.8	-1.1	-1.3	1.2	-1.1	-1.2	-1.1
Baseline Anxiety	1.2	1.2	3.3	1.1	0.6	-1.2	1.8	1.0	-0.1
Lifetime Intake	0.4	0.5	0.8	-0.7	-0.4	0.6	-0.9	-0.9	-0.1
Incentive Sensitization - Responses	1.6	1.6	2.9	-1.3	-1.2	1.3	-1.1	-1.7	-0.8
Incentive Sensitization - Breakpoint	1.8	1.8	3.1	-1.4	-1.3	1.4	-1.2	-1.8	-0.9
Progressive ratio test 1 active lever presses	0.3	0.3	0.8	-0.2	0.5	0.1	-0.8	-0.3	0.9
Progressive ratio test 1 breakpoint	0.3	0.3	0.9	-0.2	0.3	0.2	-0.9	-0.4	0.7
Progressive ratio test 1 inactive lever presses	0.4	0.5	1.0	-0.7	-0.0	0.6	-0.8	-1.0	0.5
Progressive ratio test 2 active lever presses	1.7	1.8	3.2	-1.5	-0.8	1.4	-1.6	-1.8	0.0
Progressive ratio test 2 breakpoint	1.1	1.2	2.5	-1.2	-0.6	1.2	-1.2	-1.6	0.2
Progressive ratio test 2 inactive lever presses	3.7	4.2	6.7	-2.3	-1.6	2.2	-2.3	-2.6	-0.9
Total sessions with >9 infusions	0.3	0.3	1.4	-0.2	0.6	0.1	-0.4	-0.3	1.2
Short access day 1 total inactive lever presses	0.6	0.7	1.1	-1.0	-0.4	0.9	-1.0	-0.9	0.0
Short access day 10 total inactive lever presses	0.1	0.1	0.2	-0.4	0.0	0.4	-0.0	-0.3	0.1
Short access day 1 total infusions	0.4	0.4	1.0	-0.6	-0.0	0.5	-1.0	-0.7	0.5
Short access day 10 total infusions	0.1	0.1	0.2	-0.3	-0.3	0.2	-0.2	-0.4	-0.3
Short access total infusions	0.3	0.4	0.7	-0.7	-0.5	0.5	-0.8	-0.8	-0.2
Short access day 1 locomotion	0.3	0.3	0.4	-0.6	-0.0	0.6	-0.7	-0.6	0.4
Short access day 10 total locomotion	0.0	0.0	0.1	-0.2	0.1	0.1	-0.0	-0.1	0.2
Short access total locomotion	0.4	0.4	0.7	-0.8	-0.5	0.7	-0.6	-0.7	-0.2
Compulsive drug intake	0.2	0.2	0.3	-0.5	-0.3	0.6	-0.6	-0.3	-0.1
One hour access (0.3 mA shock)	0.8	1.0	2.0	-1.1	-0.3	1.0	-1.4	-1.2	0.6
One hour access (shock baseline)	0.4	0.5	0.7	-0.7	0.0	0.6	-0.8	-0.9	0.7
Number of responses in last shaping day	0.6	0.6	1.1	-0.8	0.4	0.7	-1.0	-0.6	0.9
Context. condit. distance diff. score	0.2	0.2	0.6	0.3	0.8	-0.2	0.1	0.3	0.6
Locomotion velocity, session 1	0.3	0.3	0.6	-0.4	-0.7	0.4	-0.6	-0.5	-0.8
Locomotion distance, session 1	1.2	1.6	2.5	-1.4	-1.1	1.2	-1.6	-1.4	-0.9
Locomotion velocity, session 2	3.9	4.6	5.6	-2.3	-1.9	2.2	-2.4	-2.3	-1.7
Locomotion distance, session 2	4.1	5.9	7.8	-2.6	-2.3	2.4	-2.8	-2.5	-1.9
Locomotion velocity, session 3	1.0	1.2	1.4	-1.0	-0.9	1.2	-1.2	-1.1	-1.1
Locomotion distance, session 3	0.0	0.0	0.0	0.2	0.0	-0.0	-0.1	0.1	0.0
Stereotopy head waving bouts, day 3	4.4	5.3	7.1	2.3	2.4	-2.3	1.8	2.2	2.7
Stereotopy head waving duration, day 3	4.7	5.7	6.6	2.4	2.6	-2.4	2.0	2.4	2.6
Locomotion velocity, session 7	0.5	0.5	0.8	0.7	0.9	-0.7	0.7	0.6	0.6
Locomotion distance, session 7	0.6	0.8	1.2	1.0	0.9	-0.9	1.1	0.9	0.5
Stereotopy head waving bouts, day 7	0.1	0.1	0.3	0.1	0.3	-0.0	-0.2	0.1	0.5
Stereotopy head waving duration, day 7	0.2	0.2	0.8	0.2	0.5	-0.2	-0.1	0.2	0.9
Locomotion velocity, session 8	1.4	1.7	1.8	-1.3	-1.2	1.3	-1.3	-1.3	-1.3
Locomotion distance, session 8	2.2	3.2	5.3	-1.9	-1.3	1.9	-2.3	-1.9	-1.1
Degree of sensitization distance	0.0	0.0	0.0	-0.1	0.1	-0.0	0.2	-0.1	-0.1
Degree of sensitization stereotypy	0.6	0.7	0.9	-0.9	-0.7	1.0	-0.9	-0.8	-0.5
Condit. Reinf. active minus inactive responses	4.2	4.7	5.8	-2.2	-1.8	2.4	-2.3	-2.3	-1.8
Condit. Reinf. active-inactive response ratio	3.5	3.8	4.6	-2.1	-1.5	2.1	-2.1	-2.1	-1.6
Condit. Reinf. active responses	1.3	1.6	1.8	-1.2	-1.1	1.4	-1.2	-1.3	-1.3
Condit. Reinf. inactive responses	1.1	1.3	2.0	1.3	0.8	-1.3	1.4	1.3	0.5
Incentive salience index mean	3.2	3.8	4.5	-2.0	-1.8	2.1	-2.0	-2.1	-1.8
Condit. Reinf. lever presses	0.7	0.9	1.3	-0.8	-1.1	0.8	-0.9	-0.8	-1.1
Time in familiar zone, hab. session 1	0.0	0.0	0.1	-0.0	0.1	0.0	0.1	0.0	0.4
Time in novel zone, hab. session 1	0.1	0.1	0.4	0.1	-0.3	0.1	0.0	0.1	-0.6
Total zone transitions, hab. session 1	0.2	0.3	0.9	-0.4	0.5	0.4	-0.7	-0.4	0.9
Total locomotion distance, hab. session 1	1.5	2.2	4.0	-1.7	-0.9	1.6	-2.0	-1.7	-0.6
Locomotion velocity, hab. session 1	1.5	2.2	3.9	-1.6	-1.1	1.6	-2.0	-1.7	-0.7
Time in familiar zone, hab. session 2	0.3	0.3	1.5	0.1	0.7	-0.0	0.0	0.0	1.2
Time in novel zone, hab. session 2	0.4	0.4	1.4	0.2	-0.3	-0.3	0.6	0.3	-1.2
Total zone transitions, hab. session 2	0.5	0.7	1.0	-0.7	-0.9	0.6	-1.0	-0.7	-1.0
Total locomotion distance, hab. session 2	2.9	3.8	4.4	-1.8	-2.1	1.7	-2.1	-1.9	-2.1
Locomotion velocity, hab. session 2	2.9	4.0	4.9	-1.8	-2.2	1.7	-2.1	-1.9	-2.2
Novel to familiar place preference ratio	4.0	4.2	4.9	-2.2	-2.0	2.1	-1.8	-2.1	-2.1
Novelty place preference	4.9	5.0	5.8	-2.4	-2.2	2.3	-2.0	-2.3	-2.3
Time in novel zone, NPP test	4.6	4.9	5.7	-2.4	-2.2	2.2	-2.0	-2.3	-2.2
Total zone transitions, NPP test	0.4	0.6	2.0	-0.7	-0.4	0.6	-1.4	-0.7	-0.1
Total locomotion distance, NPP test	1.2	1.7	3.0	-1.2	-1.3	1.0	-1.7	-1.2	-1.2
Locomotion velocity, NPP test	1.1	1.6	2.9	-1.2	-1.3	1.0	-1.7	-1.2	-1.2
Pavlov. Cond. lever latency	0.0	0.0	0.1	0.0	0.3	0.0	0.2	0.0	0.3
Pavlov. Cond. magazine entry latency	0.3	0.4	0.5	-0.6	-0.7	0.6	-0.6	-0.6	-0.5
Pavlov. Cond. change in total contacts	0.1	0.1	0.3	-0.2	-0.5	0.3	-0.1	-0.2	-0.4
Pavlov. Cond. index score	0.4	0.5	0.9	-0.5	-0.9	0.5	-0.6	-0.5	-1.0
Pavlov. Cond. latency score	0.4	0.6	1.1	-0.5	-1.0	0.5	-0.6	-0.5	-1.0
Pavlov. Cond. lever contacts	0.1	0.1	0.4	-0.1	-0.6	0.0	-0.2	-0.1	-0.6
Pavlov. Cond. magazine entry number	0.4	0.5	0.7	0.6	0.7	-0.7	0.8	0.6	0.7
Pavlov. Cond. intertrial magazine entries	2.9	3.5	4.0	1.8	2.0	-1.8	1.9	1.8	2.0
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	0.9	-0.5	-1.0	0.6	-0.7	-0.5	-0.9
Pavlov. Cond. response bias	0.3	0.3	0.6	-0.4	-0.8	0.4	-0.6	-0.4	-0.7
Bone: apparent density	0.0	0.0	0.1	-0.2	0.1	0.2	-0.1	-0.2	0.0
Bone surface	0.0	0.1	0.1	-0.3	0.3	0.2	-0.3	-0.3	0.4
Bone volume	0.3	0.5	0.7	-0.9	-0.3	0.8	-0.7	-0.9	-0.4
Bone: connectivity density	0.3	0.4	0.8	0.4	0.8	-0.5	0.6	0.4	0.9
Bone: cortical apparent density	1.2	1.5	1.9	1.3	1.4	-1.2	1.2	1.2	1.1
Bone: cortical area	0.1	0.2	0.3	0.4	0.2	-0.5	0.5	0.4	-0.3
Bone: cortical porosity	0.4	0.5	0.7	-0.7	-0.6	0.7	-0.6	-0.7	-0.8
Bone: cortical porosity	0.2	0.3	0.4	-0.5	-0.4	0.6	-0.4	-0.5	-0.5
Bone: cortical thickness	0.5	0.7	1.2	0.9	0.8	-1.0	1.1	0.8	0.6
Bone: cortical thickness	0.3	0.3	0.8	0.5	0.9	-0.3	0.3	0.3	0.9
Bone: cortical tissue density	1.1	1.5	1.8	1.2	1.3	-1.2	1.2	1.2	1.1
Bone: elastic displacement	0.2	0.3	0.3	0.5	0.6	-0.4	0.6	0.5	0.5
Bone: elastic work	0.0	0.0	0.1	-0.2	-0.0	0.3	-0.0	-0.2	0.0
Bone: endosteal estimation	0.2	0.4	0.6	-0.7	-0.4	0.6	-0.8	-0.6	-0.7
Bone: endosteal perimeter	0.1	0.3	0.8	-0.3	-0.6	0.3	-0.4	-0.3	-0.9
Bone: final force	0.3	0.4	0.6	0.6	0.7	-0.7	0.8	0.7	0.4
Bone: final moment	0.3	0.5	0.7	0.7	0.7	-0.8	0.8	0.7	0.2
Bone: marrow area	0.1	0.3	0.5	-0.6	-0.3	0.5	-0.7	-0.5	-0.6
Bone: maximum diameter	0.1	0.1	0.2	0.3	0.4	-0.4	0.2	0.3	-0.0
Bone: maximum force	0.1	0.1	0.2	-0.4	-0.2	0.2	-0.2	-0.3	-0.5
Bone: maximum moment	0.1	0.1	0.4	-0.3	-0.2	0.1	-0.2	-0.3	-0.6
Bone: minimum diameter	0.0	0.1	0.4	0.2	-0.1	-0.3	0.1	0.1	-0.6
Bone: periosteal estimation	0.0	0.0	0.2	-0.0	0.0	-0.0	0.0	-0.0	-0.4
Bone: periosteal perimeter	0.0	0.1	0.1	0.2	0.1	-0.2	0.3	0.2	-0.3
Bone: post-yield work	0.0	0.0	0.1	-0.2	-0.0	0.0	-0.1	-0.1	-0.4
Bone: stiffness	0.4	0.7	1.1	-0.8	-0.9	0.7	-0.9	-0.7	-1.0
Bone: tissue strength	1.0	1.0	1.6	-0.9	-1.3	0.7	-0.9	-0.7	-1.3
Bone: trabecular number	0.0	0.0	0.1	-0.0	0.3	-0.0	0.0	-0.0	0.2
Bone: trabecular spacing	0.1	0.1	0.3	0.2	-0.3	-0.0	0.3	0.2	-0.5
Bone: trabecular thickness	0.2	0.3	0.5	-0.7	0.1	0.5	-0.5	-0.7	0.4
Bone: trabecular tissue density	2.0	2.8	3.6	-1.7	-1.6	1.8	-1.9	-1.7	-1.2
Breakpoint value in progressive ratio session	1.1	1.2	1.6	-1.1	-1.2	1.0	-1.0	-1.0	-1.3
Distance traveled before self-admin	1.2	1.2	1.9	-1.2	-0.9	1.3	-1.1	-1.4	-0.6
Distance traveled after self-admin	2.0	2.2	2.6	-1.4	-1.6	1.5	-1.5	-1.5	-1.4
Delta time in closed arm before/after self-admin	0.7	0.7	1.6	-0.6	-0.9	0.6	-0.7	-0.7	-1.2
Delta time in open arm before/after self-admin	0.8	0.8	1.1	1.0	0.8	-0.9	1.0	0.8	0.5
Diff in mean of infusions in LGA sessions	0.2	0.2	0.4	-0.4	-0.6	0.5	0.0	-0.5	-0.4
Extinction: sum of active levers before priming	0.8	0.8	1.3	0.8	1.0	-1.1	0.8	0.8	0.6
Active lever presses in extinction session 6	1.1	1.0	1.9	0.7	1.3	-0.9	0.6	0.8	1.4
Delta distance traveled before/after self-admin	0.2	0.2	0.5	-0.2	-0.7	0.2	-0.3	-0.2	-0.7
Delta ambulatory time before/after self-admin	0.4	0.5	0.8	-0.6	-0.9	0.5	-0.8	-0.5	-0.8
Time in closed arm before self-admin	0.2	0.2	1.0	-0.2	0.4	0.4	0.1	-0.1	1.0
Time in closed arm after self-admin	0.6	0.6	1.0	-0.9	-0.2	1.0	-0.8	-0.9	0.5
Time in open arm before self-admin	0.3	0.3	0.5	0.5	0.6	-0.7	0.5	0.6	0.7
Time in open arm after self-admin	2.0	2.2	2.9	1.7	1.3	-1.7	1.7	1.5	0.9
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.4	0.5	0.6	-0.6	0.5	0.5	0.5
Time to tail flick, vehicle, before self-admin	0.9	0.9	1.2	-1.0	-1.1	1.0	-0.7	-1.0	-0.8
Time to tail flick, vehicle, after self-admin	0.4	0.4	1.8	-0.2	-0.8	0.1	-0.2	-0.2	-1.3
Time to tail flick, test, before self-admin	0.4	0.4	1.4	-0.5	0.4	0.6	-0.2	-0.3	1.2
Time to tail flick, test, after self-admin	0.0	0.0	0.1	0.0	0.3	-0.3	0.3	0.0	0.1
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.4	0.4	-0.1	-0.4	0.2	0.4	-0.6
Delta time to tail flick, test, before/after SA	0.7	0.6	1.4	0.9	0.5	-1.2	0.7	0.8	-0.2
Ambulatory time before self-admin	1.5	1.5	2.3	-1.4	-1.0	1.4	-1.2	-1.5	-0.5
Ambulatory time after self-admin	2.6	2.8	3.4	-1.6	-1.8	1.6	-1.7	-1.6	-1.6
Total heroin consumption	0.6	0.8	1.2	0.8	-0.0	-1.1	1.1	0.9	-0.9
Area under the delay curve	0.2	0.2	0.3	-0.4	-0.4	0.4	-0.5	-0.6	-0.5
Delay disc. indifference point, 0s delay	0.1	0.1	0.3	-0.1	-0.4	-0.0	0.1	-0.2	-0.5
Delay disc. indifference point, 16s delay	0.0	0.0	0.1	-0.2	-0.0	0.3	-0.0	-0.3	0.2
Delay disc. indifference point, 2s delay	1.6	1.7	2.6	-1.3	-1.4	1.2	-0.9	-1.4	-1.6
Delay disc. indifference point, 24s delay	0.9	0.9	1.2	-0.9	-1.0	0.9	-0.9	-0.8	-1.1
Delay disc. indifference point, 4s delay	0.0	0.0	0.1	-0.1	-0.0	0.1	-0.1	-0.3	0.2
Delay disc. indifference point, 8s delay	0.1	0.1	0.2	0.5	0.4	-0.4	0.2	0.3	0.1
Delay discount exponential model param	0.3	0.4	0.6	0.6	0.6	-0.6	0.6	0.7	0.6
Delay discount hyperbolic model param	0.4	0.4	0.6	0.6	0.6	-0.6	0.6	0.8	0.7
Fecal boli incidents, locomotor time 1	0.2	0.2	0.4	-0.4	-0.5	0.3	-0.2	-0.7	-0.3
Change in fecal boli incidents, locomotor task	0.3	0.3	0.4	-0.6	-0.6	0.6	-0.6	-0.2	-0.5
Time >=10cm from walls, locomotor time 1	0.5	0.5	0.8	0.6	0.8	-0.6	0.8	0.5	0.9
Bouts of movement, locomotor time 1	0.5	0.6	0.9	1.0	0.2	-1.0	0.7	0.9	-0.5
Total resting periods, locomotor time 1	0.7	0.8	1.3	1.1	0.1	-1.1	0.8	1.0	-0.8
Rest time, locomotor task time 1	1.5	1.6	2.8	1.6	0.8	-1.4	1.3	1.7	0.2
Distance moved, locomotor task time 1	0.3	0.4	1.4	0.0	0.8	0.0	0.0	0.3	1.2
Vertical activity count, locomotor time 1	0.0	0.0	0.0	-0.2	0.1	0.2	0.1	0.1	0.2
Time >=10cm from walls, locomotor time 2	0.0	0.0	0.2	-0.0	0.1	-0.0	0.3	-0.0	0.4
Bouts of movement, locomotor time 2	0.6	0.6	1.2	-0.6	-0.8	0.6	-0.6	-0.9	-1.1
Total resting periods, locomotor time 2	0.7	0.8	1.8	-0.6	-0.9	0.6	-0.6	-0.9	-1.3
Rest time, locomotor task time 2	0.6	0.7	1.2	1.0	0.1	-1.0	1.1	0.8	-0.4
Distance moved, locomotor task time 2	1.8	2.1	4.5	1.0	1.9	-0.9	1.0	1.3	2.1
Vertical activity count, locomotor time 2	1.1	1.2	2.4	0.8	1.4	-0.7	0.4	1.2	1.5
Weight adjusted by age	0.1	0.1	0.2	0.2	0.1	-0.3	0.1	0.4	-0.3
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.2	-0.3	-0.4	0.3	-0.4	-0.3	-0.0
Locomotion in novel chamber	0.0	0.0	0.1	-0.1	0.0	0.2	0.2	-0.1	-0.0
Locomotion in novel chamber post-restriction	3.6	4.3	5.9	2.4	2.1	-2.4	1.3	2.2	1.7
Progressive ratio	3.4	3.9	4.8	-2.0	-2.0	2.2	-1.9	-2.0	-1.8
Food seeking constrained by brief footshock	4.4	5.4	7.5	-2.2	-2.7	2.3	-1.8	-2.2	-2.6
Seeking ratio, punishment vs. effort	0.7	0.9	1.2	1.0	0.7	-1.1	1.0	1.1	0.6
Run reversals in cocaine runway, females	0.9	0.9	2.2	0.8	-0.4	-0.8	0.8	1.0	-1.5
Run reversals in cocaine runway, males	0.2	0.2	0.8	0.4	-0.2	-0.4	-0.2	0.4	-0.9
Latency to leave start box in cocaine runway	1.3	1.5	2.3	1.2	1.4	-1.1	0.9	1.0	1.5
Latency to leave start box in cocaine runway, F	1.5	1.6	2.0	1.3	1.3	-1.1	1.4	1.2	1.3
Latency to leave start box in cocaine runway, M	0.3	0.3	0.7	0.3	0.5	-0.2	-0.6	0.2	0.8
Cd content in liver	0.2	0.2	0.6	0.2	0.8	-0.3	0.3	0.3	0.6
Co content in liver	0.7	0.8	1.2	1.0	0.5	-1.1	0.9	1.1	0.2
Cu content in liver	0.2	0.2	0.4	0.4	0.4	-0.6	0.6	0.5	-0.2
Fe content in liver	1.2	1.4	2.8	0.8	1.6	-0.8	1.0	0.8	1.7
K content in liver	1.0	1.0	2.0	1.4	0.5	-1.2	0.8	1.3	0.2
Mg content in liver	1.7	1.7	3.1	1.8	0.9	-1.5	1.1	1.6	0.6
Mn content in liver	0.2	0.3	0.6	0.5	0.5	-0.3	-0.0	0.5	0.8
Na content in liver	0.4	0.4	0.8	-0.4	-0.8	0.6	-0.9	-0.5	-0.7
Rb content in liver	21.1	26.4	31.0	5.6	5.0	-5.1	5.3	5.2	4.6
Se content in liver	0.0	0.0	0.0	-0.1	-0.2	0.0	-0.1	-0.1	-0.2
Sr content in liver	0.2	0.2	0.8	0.1	-0.2	-0.1	0.2	0.1	-0.9
Zn content in liver	0.5	0.5	0.8	0.9	0.7	-0.8	0.7	0.8	0.2