Abtb2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000008510 0.07 0.06 8.7e-04 0.04 0.04 0.01 0.04 3.0e-03 2.4e-03 5.2e-02 3.9e-03
2 Brain gene expression ENSRNOG00000008510 0.27 0.15 0.0e+00 0.18 0.18 0.17 0.17 2.1e-16 2.0e-16 5.7e-16 2.3e-15
3 Eye gene expression ENSRNOG00000008510 0.32 0.22 3.9e-03 0.19 0.18 0.13 0.16 7.8e-04 1.1e-03 4.6e-03 2.0e-03
4 LHb gene expression ENSRNOG00000008510 0.14 0.11 2.1e-03 0.03 0.08 0.06 0.03 6.5e-02 5.2e-03 1.8e-02 5.9e-02
5 Liver gene expression ENSRNOG00000008510 0.21 0.13 0.0e+00 0.18 0.19 0.18 0.18 4.5e-20 1.6e-20 5.5e-20 6.9e-20
6 OFC gene expression ENSRNOG00000008510 0.14 0.11 2.3e-03 0.08 0.06 0.09 0.08 6.1e-03 1.9e-02 4.0e-03 6.0e-03
7 PL gene expression ENSRNOG00000008510 0.03 0.03 6.6e-03 0.01 0.02 0.01 0.02 2.3e-02 7.4e-03 5.8e-02 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.10.30.7-0.5-0.70.8-0.50.5-0.5-0.5
BMI without tail0.40.81.1-0.9-0.81.0-0.90.9-0.9-0.9
Body weight0.62.63.3-1.6-1.31.8-1.51.5-1.8-1.6
Epididymis fat weight0.92.12.3-1.4-1.51.5-1.41.4-1.5-1.4
Glucose2.13.24.0-1.8-1.61.7-1.81.8-2.0-1.8
Heart weight0.20.40.70.50.6-0.80.5-0.60.40.5
Left kidney weight0.61.83.0-1.3-1.01.6-1.21.2-1.7-1.3
Right kidney weight0.51.42.6-1.1-1.01.6-1.01.0-1.4-1.1
Tail length0.41.21.8-1.2-0.61.1-1.11.1-1.3-1.2
Length with tail0.51.82.5-1.4-0.91.3-1.41.3-1.6-1.5
Length without tail0.30.70.9-0.8-0.70.8-0.80.8-1.0-0.8
Liver weight, left0.20.30.6-0.6-0.20.5-0.60.6-0.7-0.7
Liver weight, right1.32.23.1-1.5-1.21.5-1.51.5-1.7-1.5
Parametrial fat weight0.71.41.7-1.2-1.21.3-1.21.2-1.1-1.2
Retroperitoneal fat weight9.330.832.9-5.5-5.75.5-5.55.5-5.7-5.5
Intraocular pressure0.00.00.10.0-0.3-0.0-0.00.00.10.0
Extensor digitorum longus weight0.31.21.61.01.2-1.11.0-1.11.11.0
Soleus weight1.64.85.22.32.1-1.92.3-2.22.32.3
Tibialis anterior weight2.910.111.03.13.3-3.23.1-3.13.23.1
Tibia length0.10.41.20.51.1-0.80.5-0.60.30.4
Number of licking bursts0.30.30.6-0.6-0.80.4-0.60.6-0.5-0.6
Food consumed during 24 hour testing period7.38.89.9-3.0-2.82.9-3.03.0-3.1-3.0
Times rat made contact with spout0.10.20.2-0.4-0.40.4-0.40.4-0.4-0.4
Mean time between licks in bursts0.91.31.81.21.0-1.01.2-1.11.31.2
Mean num. licks in bursts0.00.00.10.10.20.00.1-0.10.00.1
Std. dev. time between licks in bursts0.40.40.80.60.7-0.90.6-0.60.70.6
Water consumed over 24 hours0.20.20.3-0.5-0.40.4-0.50.5-0.6-0.5
Indifference point 0 sec0.30.50.90.70.2-0.60.7-0.70.90.8
Indifference point AUC1.61.92.81.31.7-1.31.3-1.31.41.3
Indifference point function ln k1.01.51.8-1.2-1.41.2-1.21.2-1.2-1.2
Indifference point function log k1.01.51.8-1.2-1.41.2-1.21.2-1.2-1.2
Delay discounting total patch changes 0 sec0.20.40.70.60.0-0.50.6-0.60.80.7
Delay discounting total patch changes 12 sec0.00.00.0-0.1-0.20.2-0.10.10.1-0.1
Delay discounting total patch changes 18 sec0.50.70.90.80.8-0.90.8-0.81.00.8
Delay discounting total patch changes 24 sec1.31.61.91.31.1-1.31.3-1.21.41.3
Delay discounting total patch changes 6 sec0.40.50.70.80.6-0.60.7-0.70.90.8
Delay discounting time to switch 0 sec0.00.00.00.20.2-0.20.2-0.20.10.2
Delay discounting water rate 0 sec0.00.00.1-0.1-0.30.1-0.10.10.0-0.0
Delay discounting water rate 12 sec0.10.20.40.30.5-0.60.3-0.30.20.3
Delay discounting water rate 18 sec0.91.21.5-1.1-1.11.1-1.11.1-1.2-1.1
Delay discounting water rate 24 sec0.00.10.20.10.4-0.50.1-0.1-0.10.0
Delay discounting water rate 6 sec0.00.00.0-0.0-0.1-0.0-0.10.1-0.2-0.0
Locomotor activity0.00.10.2-0.2-0.50.1-0.30.3-0.0-0.2
Locomotor testing distance1.21.92.2-1.4-1.51.2-1.41.4-1.3-1.4
Locomotor testing rearing0.10.20.2-0.4-0.50.2-0.50.4-0.4-0.4
Light reinforcement 10.10.20.4-0.4-0.10.5-0.30.3-0.6-0.4
Light reinforcement 20.00.00.1-0.10.20.1-0.10.1-0.2-0.1
Reaction time number correct0.00.00.1-0.10.1-0.3-0.10.1-0.1-0.1
Reaction time mean minus median0.20.20.4-0.4-0.40.6-0.40.4-0.5-0.4
Reaction time mean minus median AUC0.10.20.3-0.4-0.40.5-0.40.4-0.4-0.4
Reaction time num false alarms1.31.92.91.31.2-1.31.3-1.31.71.3
Reaction time num false alarms AUC2.02.84.11.61.6-1.71.6-1.62.01.6
Reaction time trials correct on left0.00.00.1-0.10.1-0.3-0.10.1-0.1-0.1
Reaction time trials on left0.00.00.1-0.00.2-0.4-0.0-0.00.0-0.0
Reaction time mean0.20.30.4-0.5-0.40.5-0.50.5-0.6-0.5
Reaction time mean AUC0.30.50.7-0.7-0.50.7-0.70.7-0.8-0.7
Median of all reaction times0.40.50.8-0.7-0.60.7-0.70.7-0.9-0.7
Reaction time omissions1.21.61.71.31.1-1.21.3-1.31.31.3
Reaction time false alarm rate2.43.44.91.81.6-1.61.8-1.82.21.9
Reaction time premature initiation rate0.20.20.50.40.7-0.60.4-0.40.40.4
Reaction time premature initiations0.10.20.50.30.7-0.70.3-0.40.30.3
Std. dev. reaction times0.00.00.0-0.1-0.00.2-0.10.1-0.1-0.1
Reaction time trials completed0.00.00.1-0.00.2-0.4-0.0-0.00.0-0.0
Reaction time trials AUC0.00.00.1-0.30.0-0.2-0.20.2-0.2-0.2
Social response proportion4.85.25.82.22.4-2.32.2-2.22.42.2
Social responses0.00.00.1-0.2-0.10.3-0.20.2-0.1-0.2
Social time2.63.44.11.81.8-1.81.8-1.82.01.8
Conditioned locomotion3.74.45.02.12.0-2.12.1-2.12.22.1
Cocaine response after cond. corrected2.62.93.41.71.7-1.51.7-1.71.81.7
Cocaine response after cond. not corrected0.50.50.70.70.7-0.80.7-0.70.80.7
Cocaine response before conditioning5.87.17.8-2.7-2.62.3-2.72.7-2.8-2.7
Saline control response0.70.91.0-1.0-1.00.8-1.01.0-0.9-1.0
Condit. Reinf. active minus inactive responses1.41.72.2-1.4-1.21.0-1.41.3-1.5-1.4
Condit. Reinf. active-inactive response ratio3.94.15.0-2.1-1.81.7-2.12.1-2.2-2.1
Condit. Reinf. active responses0.91.31.6-1.1-1.11.0-1.11.1-1.3-1.1
Condit. Reinf. inactive responses0.00.00.00.2-0.10.10.1-0.10.10.2
Condit. Reinf. lever presses0.60.91.1-0.9-1.00.7-0.90.9-1.1-0.9
Condit. Reinf. lever reinforcers received0.91.21.5-1.1-1.21.0-1.11.1-1.2-1.1
Pavlov. Cond. lever latency2.23.03.41.71.8-1.41.8-1.81.81.7
Pavlov. Cond. magazine entry latency0.91.01.3-0.9-1.21.0-1.01.0-1.0-0.9
Pavlov. Cond. change in total contacts1.01.41.7-1.2-1.31.0-1.21.2-1.2-1.2
Pavlov. Cond. index score2.02.63.1-1.6-1.81.4-1.61.6-1.7-1.6
Pavlov. Cond. latency score2.53.13.7-1.7-1.91.6-1.81.8-1.8-1.7
Pavlov. Cond. lever contacts2.63.64.2-1.9-2.01.6-1.91.9-2.0-1.9
Pavlov. Cond. magazine entry number0.50.60.80.70.9-0.80.7-0.70.80.7
Pavlov. Cond. intertrial magazine entries0.00.10.10.20.4-0.20.2-0.20.30.2
Pavlov. Cond. lever-magazine prob. diff.1.72.22.6-1.5-1.61.3-1.51.5-1.6-1.5
Pavlov. Cond. response bias1.92.63.0-1.6-1.71.3-1.61.6-1.7-1.6
Conditioned reinforcement - actives3.63.53.9-2.0-1.51.9-1.91.9-2.0-2.0
Conditioned reinforcement - inactives8.910.110.3-3.2-3.23.0-3.23.2-3.2-3.2
Conditioned locomotion2.42.94.7-1.5-1.82.2-1.51.6-1.7-1.5
Intermittent access intake day 1-15 change0.20.20.3-0.4-0.50.3-0.40.4-0.4-0.3
Intermittent access intake escalation0.50.50.6-0.7-0.80.7-0.70.7-0.7-0.6
Intermittent access intake escalation 23.02.93.2-1.7-1.81.6-1.71.7-1.8-1.7
Intermitt. access day 1 inactive lever presses0.00.00.2-0.00.4-0.10.0-0.1-0.2-0.0
Intermitt. access day 15 inactive lever presses3.33.64.8-1.8-1.82.2-1.81.8-2.1-1.8
Intermitt. access escalation Index0.20.20.3-0.6-0.2-0.1-0.50.5-0.3-0.6
Intermittent access day 1 total infusions3.64.04.7-2.0-2.02.2-2.02.0-1.9-2.0
Intermittent access day 15 total infusions5.05.65.9-2.3-2.42.4-2.32.4-2.4-2.3
Intermittent access terminal intake (last 3 days)6.87.47.6-2.7-2.72.7-2.72.7-2.7-2.7
Intermittent access total infusions6.87.57.6-2.8-2.82.7-2.82.8-2.7-2.7
Intermittent access day 1 locomotion1.61.62.3-1.2-1.41.5-1.21.2-1.1-1.2
Intermittent access day 15 total locomotion2.02.23.6-1.2-1.91.9-1.31.3-1.2-1.2
Intermittent access total locomotion2.62.94.2-1.6-2.02.0-1.61.6-1.5-1.5
Intermittent access standard deviation6.67.18.4-2.6-2.72.9-2.62.6-2.7-2.5
Cocaine induced anxiety0.30.40.6-0.6-0.50.5-0.60.6-0.8-0.6
Post-drug Anxiety0.00.00.0-0.00.10.2-0.00.0-0.1-0.0
Baseline Anxiety2.62.83.51.71.5-1.41.7-1.71.91.7
Lifetime Intake7.28.08.2-2.9-2.82.8-2.82.9-2.8-2.8
Incentive Sensitization - Responses1.11.11.2-1.1-1.01.1-1.11.1-1.1-1.1
Incentive Sensitization - Breakpoint1.01.01.1-1.0-1.01.0-1.01.0-1.0-1.0
Progressive ratio test 1 active lever presses3.94.04.2-2.0-1.91.9-2.02.0-2.0-2.0
Progressive ratio test 1 breakpoint3.63.74.0-2.0-1.81.8-1.91.9-2.0-2.0
Progressive ratio test 1 inactive lever presses2.12.32.7-1.5-1.31.6-1.51.5-1.7-1.5
Progressive ratio test 2 active lever presses2.93.13.3-1.8-1.71.8-1.71.7-1.8-1.7
Progressive ratio test 2 breakpoint3.53.94.3-2.0-1.91.9-2.02.0-2.1-2.0
Progressive ratio test 2 inactive lever presses4.04.75.1-2.1-2.12.2-2.12.1-2.3-2.1
Total sessions with >9 infusions2.22.42.6-1.6-1.51.5-1.61.6-1.5-1.6
Short access day 1 total inactive lever presses0.80.91.2-1.0-1.10.7-1.01.0-0.9-1.0
Short access day 10 total inactive lever presses0.20.20.5-0.4-0.20.5-0.40.3-0.7-0.4
Short access day 1 total infusions9.29.810.4-3.2-3.02.9-3.23.2-3.2-3.2
Short access day 10 total infusions3.94.35.3-2.1-2.32.1-2.12.1-1.9-2.0
Short access total infusions5.66.26.5-2.5-2.52.4-2.52.5-2.4-2.5
Short access day 1 locomotion4.24.45.4-2.1-2.32.1-2.12.1-2.0-2.0
Short access day 10 total locomotion3.84.15.7-1.8-2.32.4-1.91.9-2.0-1.8
Short access total locomotion3.73.84.8-1.9-2.22.1-1.91.9-1.9-1.8
Compulsive drug intake1.91.92.11.41.4-1.11.4-1.41.31.4
One hour access (0.3 mA shock)3.54.15.8-1.9-2.12.4-1.91.9-2.0-1.9
One hour access (shock baseline)6.67.78.5-2.7-2.92.8-2.72.8-2.8-2.7
Number of responses in last shaping day1.61.71.9-1.4-1.11.1-1.41.3-1.4-1.4
Context. condit. distance diff. score3.13.84.6-2.0-1.81.7-2.02.0-2.2-2.0
Locomotion velocity, session 10.10.10.10.20.3-0.30.2-0.30.20.2
Locomotion distance, session 10.00.00.00.0-0.10.00.0-0.00.00.1
Locomotion velocity, session 20.00.00.00.00.1-0.20.0-0.00.10.0
Locomotion distance, session 20.20.30.4-0.5-0.60.7-0.50.5-0.5-0.5
Locomotion velocity, session 30.10.10.2-0.2-0.50.5-0.20.2-0.1-0.2
Locomotion distance, session 30.20.20.4-0.4-0.60.6-0.40.5-0.5-0.4
Stereotopy head waving bouts, day 30.00.00.10.2-0.00.10.2-0.20.30.2
Stereotopy head waving duration, day 30.40.50.5-0.7-0.70.6-0.70.7-0.6-0.7
Locomotion velocity, session 70.00.00.1-0.10.10.3-0.10.1-0.3-0.1
Locomotion distance, session 70.40.50.80.70.9-0.60.7-0.70.60.7
Stereotopy head waving bouts, day 70.10.10.2-0.2-0.40.3-0.20.3-0.1-0.2
Stereotopy head waving duration, day 70.00.00.0-0.2-0.20.1-0.20.2-0.0-0.2
Locomotion velocity, session 80.50.60.8-0.7-0.60.8-0.70.7-0.9-0.8
Locomotion distance, session 83.14.75.6-2.2-2.02.2-2.22.2-2.4-2.2
Degree of sensitization distance0.50.50.90.60.9-0.80.6-0.70.50.6
Degree of sensitization stereotypy0.00.00.0-0.0-0.2-0.0-0.00.00.1-0.0
Condit. Reinf. active minus inactive responses1.51.62.0-1.3-1.41.1-1.31.3-1.2-1.3
Condit. Reinf. active-inactive response ratio3.13.33.8-1.8-1.91.7-1.81.9-1.8-1.8
Condit. Reinf. active responses0.50.60.8-0.8-0.90.7-0.80.8-0.7-0.8
Condit. Reinf. inactive responses0.50.60.70.70.8-0.70.7-0.70.80.7
Incentive salience index mean1.31.61.8-1.3-1.41.1-1.31.3-1.2-1.3
Condit. Reinf. lever presses1.01.31.5-1.2-1.11.0-1.21.2-1.0-1.2
Time in familiar zone, hab. session 10.70.60.80.80.9-0.70.8-0.80.90.8
Time in novel zone, hab. session 11.31.31.6-1.1-1.21.0-1.11.1-1.2-1.1
Total zone transitions, hab. session 12.23.14.0-1.7-2.01.8-1.71.7-1.7-1.7
Total locomotion distance, hab. session 10.81.22.2-0.9-1.51.3-1.01.0-0.9-0.9
Locomotion velocity, hab. session 10.50.71.6-0.7-1.31.0-0.70.8-0.6-0.6
Time in familiar zone, hab. session 20.00.00.10.1-0.30.40.1-0.00.10.1
Time in novel zone, hab. session 20.10.10.1-0.30.2-0.2-0.30.2-0.4-0.3
Total zone transitions, hab. session 21.72.22.6-1.5-1.41.6-1.41.4-1.6-1.4
Total locomotion distance, hab. session 20.00.00.10.1-0.20.40.1-0.0-0.00.1
Locomotion velocity, hab. session 20.00.00.10.1-0.10.30.1-0.10.10.1
Novel to familiar place preference ratio0.90.91.3-0.9-1.11.1-0.90.9-0.9-0.9
Novelty place preference0.80.91.2-0.9-1.01.1-0.90.9-0.9-0.9
Time in novel zone, NPP test0.60.60.7-0.7-0.90.9-0.70.7-0.8-0.7
Total zone transitions, NPP test0.50.70.90.80.7-1.00.8-0.81.00.9
Total locomotion distance, NPP test0.40.60.80.80.5-0.70.8-0.80.90.9
Locomotion velocity, NPP test0.30.50.60.80.4-0.50.7-0.70.80.8
Pavlov. Cond. lever latency0.50.60.70.80.7-0.70.8-0.80.70.8
Pavlov. Cond. magazine entry latency0.91.11.3-1.1-0.81.0-1.11.1-1.1-1.1
Pavlov. Cond. change in total contacts0.20.20.30.40.5-0.40.4-0.50.50.4
Pavlov. Cond. index score0.20.30.3-0.6-0.40.6-0.60.6-0.5-0.6
Pavlov. Cond. latency score0.30.30.4-0.6-0.50.6-0.60.6-0.5-0.6
Pavlov. Cond. lever contacts0.30.40.5-0.7-0.50.4-0.70.7-0.5-0.7
Pavlov. Cond. magazine entry number0.81.01.21.00.8-1.01.0-1.01.11.1
Pavlov. Cond. intertrial magazine entries0.00.00.10.1-0.1-0.30.1-0.10.10.1
Pavlov. Cond. lever-magazine prob. diff.0.20.20.3-0.5-0.40.5-0.50.5-0.4-0.5
Pavlov. Cond. response bias0.70.91.1-1.0-0.70.8-1.01.0-1.0-1.0
Bone: apparent density0.61.01.3-1.0-1.11.0-1.01.0-1.0-1.0
Bone surface0.61.11.2-1.0-1.11.0-1.01.0-1.1-1.0
Bone volume1.52.63.0-1.6-1.71.6-1.61.6-1.6-1.6
Bone: connectivity density0.50.91.0-0.9-1.00.8-0.91.0-0.9-0.9
Bone: cortical apparent density0.10.10.30.40.6-0.20.4-0.40.20.4
Bone: cortical area0.20.30.6-0.6-0.10.5-0.50.5-0.8-0.6
Bone: cortical porosity0.40.50.60.70.6-0.70.7-0.70.80.7
Bone: cortical porosity0.20.20.30.40.5-0.50.4-0.40.40.4
Bone: cortical thickness0.00.00.1-0.10.40.0-0.10.0-0.2-0.1
Bone: cortical thickness3.54.14.61.92.1-2.12.0-2.02.01.9
Bone: cortical tissue density0.10.10.20.30.5-0.10.3-0.30.10.3
Bone: elastic displacement1.72.02.71.31.6-1.51.4-1.41.21.3
Bone: elastic work1.31.82.31.31.5-1.31.3-1.31.21.3
Bone: endosteal estimation0.10.30.30.60.5-0.60.6-0.60.50.6
Bone: endosteal perimeter0.30.70.9-0.8-0.90.8-0.80.8-1.0-0.8
Bone: final force0.00.00.1-0.00.3-0.0-0.0-0.0-0.2-0.0
Bone: final moment0.10.10.40.30.6-0.30.3-0.40.10.3
Bone: marrow area0.10.30.30.60.5-0.60.6-0.60.50.6
Bone: maximum diameter0.20.40.8-0.7-0.40.6-0.60.6-0.9-0.7
Bone: maximum force0.00.10.2-0.2-0.10.3-0.20.2-0.4-0.3
Bone: maximum moment0.00.00.10.20.3-0.10.2-0.20.10.2
Bone: minimum diameter0.71.31.9-1.2-0.81.1-1.21.1-1.4-1.2
Bone: periosteal estimation0.00.00.10.10.3-0.10.1-0.1-0.10.1
Bone: periosteal perimeter1.22.02.6-1.4-1.21.5-1.41.4-1.6-1.4
Bone: post-yield work0.00.00.00.0-0.2-0.10.0-0.00.20.1
Bone: stiffness0.40.70.9-0.8-0.70.9-0.80.8-1.0-0.8
Bone: tissue strength0.00.00.10.3-0.10.00.3-0.20.20.3
Bone: trabecular number0.50.70.9-0.9-0.90.7-0.90.9-0.9-0.9
Bone: trabecular spacing0.20.20.4-0.4-0.40.6-0.40.4-0.5-0.4
Bone: trabecular thickness0.20.20.2-0.5-0.50.5-0.50.5-0.4-0.5
Bone: trabecular tissue density1.21.71.81.31.2-1.01.4-1.31.41.4
Breakpoint value in progressive ratio session1.51.72.51.21.6-1.31.2-1.21.21.2
Distance traveled before self-admin0.60.70.9-0.8-0.70.9-0.80.8-0.9-0.8
Distance traveled after self-admin0.60.71.2-0.9-0.40.8-0.80.8-1.1-0.9
Delta time in closed arm before/after self-admin0.00.00.00.20.20.20.2-0.2-0.10.1
Delta time in open arm before/after self-admin0.20.20.40.4-0.0-0.50.4-0.30.60.4
Diff in mean of infusions in LGA sessions0.20.30.60.40.8-0.60.4-0.50.40.4
Extinction: sum of active levers before priming0.20.20.8-0.3-0.10.9-0.20.2-0.5-0.3
Active lever presses in extinction session 60.20.20.4-0.4-0.30.7-0.40.4-0.5-0.4
Delta distance traveled before/after self-admin0.20.20.70.40.8-0.50.4-0.40.30.4
Delta ambulatory time before/after self-admin0.10.10.40.20.6-0.30.2-0.20.00.2
Time in closed arm before self-admin1.51.82.3-1.5-1.10.7-1.51.4-1.3-1.5
Time in closed arm after self-admin0.60.60.9-0.8-0.70.6-0.80.8-0.9-0.9
Time in open arm before self-admin1.51.61.91.31.2-0.91.3-1.31.41.4
Time in open arm after self-admin2.12.33.21.61.1-1.21.6-1.51.81.6
Sum of active levers in priming session hrs 5-60.70.71.40.91.2-0.40.9-0.90.50.8
Time to tail flick, vehicle, before self-admin4.24.35.5-1.9-2.32.3-1.92.0-2.1-1.9
Time to tail flick, vehicle, after self-admin5.05.45.6-2.3-2.42.3-2.32.3-2.3-2.3
Time to tail flick, test, before self-admin1.51.51.7-1.2-1.31.0-1.31.3-1.3-1.2
Time to tail flick, test, after self-admin2.72.73.8-1.6-2.01.6-1.61.7-1.6-1.6
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.2-0.1-0.1-0.20.2-0.1-0.2
Delta time to tail flick, test, before/after SA0.00.00.1-0.1-0.40.3-0.10.10.1-0.1
Ambulatory time before self-admin0.40.40.5-0.7-0.40.6-0.60.6-0.7-0.7
Ambulatory time after self-admin0.91.01.8-1.0-0.40.8-1.00.9-1.3-1.1
Total heroin consumption1.21.52.01.21.4-0.91.3-1.21.21.2
Area under the delay curve0.20.20.30.40.2-0.50.4-0.40.60.4
Delay disc. indifference point, 0s delay0.00.00.0-0.00.1-0.1-0.00.0-0.0-0.0
Delay disc. indifference point, 16s delay1.71.72.01.21.3-1.41.3-1.31.41.2
Delay disc. indifference point, 2s delay0.20.30.60.40.5-0.80.4-0.40.50.4
Delay disc. indifference point, 24s delay0.20.20.30.40.3-0.50.4-0.40.60.4
Delay disc. indifference point, 4s delay0.10.20.30.30.3-0.60.3-0.30.40.3
Delay disc. indifference point, 8s delay0.30.30.5-0.5-0.70.4-0.50.5-0.3-0.5
Delay discount exponential model param0.20.20.4-0.5-0.30.6-0.40.4-0.6-0.5
Delay discount hyperbolic model param0.20.20.3-0.4-0.20.6-0.40.4-0.5-0.4
Fecal boli incidents, locomotor time 18.39.010.92.83.3-3.22.9-2.93.12.8
Change in fecal boli incidents, locomotor task6.46.17.9-2.3-2.82.7-2.42.4-2.3-2.3
Time >=10cm from walls, locomotor time 10.10.10.30.30.5-0.50.3-0.30.40.3
Bouts of movement, locomotor time 10.80.91.40.81.2-1.10.8-0.81.00.8
Total resting periods, locomotor time 10.60.71.30.71.1-1.00.7-0.80.80.7
Rest time, locomotor task time 10.40.41.00.51.0-0.80.5-0.60.50.5
Distance moved, locomotor task time 12.12.32.7-1.4-1.61.5-1.51.5-1.5-1.4
Vertical activity count, locomotor time 10.10.10.4-0.3-0.60.4-0.30.4-0.3-0.3
Time >=10cm from walls, locomotor time 26.46.77.7-2.6-2.52.4-2.62.6-2.8-2.6
Bouts of movement, locomotor time 20.10.10.20.40.5-0.20.4-0.4-0.00.4
Total resting periods, locomotor time 20.10.10.10.30.4-0.10.3-0.3-0.10.3
Rest time, locomotor task time 22.02.32.81.51.5-1.51.5-1.51.71.5
Distance moved, locomotor task time 24.45.26.3-2.3-2.12.1-2.32.3-2.5-2.3
Vertical activity count, locomotor time 22.52.83.8-1.6-1.51.6-1.61.6-2.0-1.6
Weight adjusted by age2.52.83.31.71.6-1.61.7-1.71.81.7
Seeking ratio, delayed vs. immediate footshock0.20.20.2-0.4-0.40.3-0.50.5-0.5-0.5
Locomotion in novel chamber0.50.71.0-0.8-1.00.9-0.80.8-0.7-0.8
Locomotion in novel chamber post-restriction1.01.21.51.01.0-1.21.0-1.01.21.0
Progressive ratio0.40.50.7-0.7-0.60.8-0.70.7-0.8-0.7
Food seeking constrained by brief footshock1.01.21.4-1.1-1.21.2-1.11.1-1.1-1.1
Seeking ratio, punishment vs. effort0.20.20.30.50.2-0.50.4-0.40.60.5
Run reversals in cocaine runway, females0.10.10.2-0.4-0.10.5-0.30.3-0.5-0.4
Run reversals in cocaine runway, males5.14.95.32.32.2-2.02.3-2.32.22.3
Latency to leave start box in cocaine runway0.10.10.20.50.1-0.20.5-0.40.40.5
Latency to leave start box in cocaine runway, F0.10.10.10.4-0.10.10.3-0.30.20.4
Latency to leave start box in cocaine runway, M0.20.20.30.40.5-0.50.4-0.40.40.4
Cd content in liver1.21.31.5-1.1-1.21.2-1.11.1-1.1-1.1
Co content in liver1.41.62.01.21.2-1.41.2-1.21.41.2
Cu content in liver0.30.40.50.60.6-0.70.6-0.60.70.6
Fe content in liver0.70.81.40.80.9-1.20.8-0.80.90.8
K content in liver2.42.42.71.61.5-1.31.6-1.61.61.6
Mg content in liver2.02.02.21.41.5-1.41.4-1.41.51.4
Mn content in liver1.92.22.51.41.6-1.51.4-1.51.41.4
Na content in liver0.10.10.20.20.5-0.30.2-0.20.20.2
Rb content in liver1.51.82.01.31.4-1.41.3-1.31.31.3
Se content in liver3.74.55.52.11.8-2.32.1-2.12.32.1
Sr content in liver0.10.10.10.30.3-0.30.3-0.30.30.3
Zn content in liver0.10.10.10.40.4-0.40.4-0.40.40.4