Hub : Genes

Bsg

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000008414 0.54 0.18 0.0e+00 0.29 0.28 0.29 0.29 1.9e-32 2.0e-31 3.3e-32 5.6e-32
2 BLA gene expression ENSRNOG00000008414 0.41 0.2 1.9e-07 0.12 0.14 0.14 0.14 3.8e-07 1.0e-07 6.2e-08 1.0e-07
3 Brain gene expression ENSRNOG00000008414 0.45 0.15 0.0e+00 0.26 0.26 0.27 0.27 3.6e-24 2.2e-24 6.0e-25 7.6e-25
4 Brain mRNA stability ENSRNOG00000008414 0.04 0.03 1.9e-04 0.03 0.03 0.03 0.03 2.1e-03 4.7e-04 1.7e-03 1.4e-03
5 IL alternative polyA ENSRNOT00000011275 0.47 0.22 3.3e-03 0.01 0.03 0.04 0.04 1.4e-01 5.8e-02 3.4e-02 3.8e-02
6 IL alternative polyA ENSRNOT00000098215 0.4 0.22 5.0e-03 0.07 0.03 0.04 0.03 1.2e-02 6.1e-02 3.2e-02 6.1e-02
7 IL gene expression ENSRNOG00000008414 0.25 0.18 1.7e-03 0.05 0.09 0.07 0.07 2.1e-02 4.4e-03 8.1e-03 9.2e-03
8 LHb gene expression ENSRNOG00000008414 0.19 0.14 2.3e-03 0.09 0.08 -0 0.07 3.3e-03 5.3e-03 3.5e-01 8.0e-03
9 Liver gene expression ENSRNOG00000008414 0.34 0.16 0.0e+00 0.18 0.17 0.17 0.18 9.2e-20 1.6e-18 5.1e-19 2.8e-19
10 NAcc gene expression ENSRNOG00000008414 0.19 0.11 2.4e-06 0.08 0.08 0.08 0.08 1.3e-06 8.0e-07 1.2e-06 1.6e-06
11 OFC gene expression ENSRNOG00000008414 0.54 0.21 2.7e-07 0.29 0.26 0.27 0.26 1.5e-07 8.3e-07 4.0e-07 8.4e-07
12 PL alternative TSS ENSRNOT00000011275 0.11 0.09 7.5e-03 0.02 0.03 0.03 0.03 1.2e-02 1.9e-03 1.5e-03 3.5e-03
13 PL alternative TSS ENSRNOT00000105142 0.12 0.09 7.7e-03 0.02 0.03 0.03 0.03 1.7e-02 2.1e-03 1.5e-03 3.9e-03
14 PL alternative TSS ENSRNOT00000105142 0.1 0.08 7.6e-03 0.03 0.03 0.03 0.03 2.2e-03 1.3e-03 1.4e-03 1.8e-03
15 PL gene expression ENSRNOG00000008414 0.51 0.23 1.0e-13 0.16 0.18 0.18 0.18 4.6e-12 1.7e-13 4.8e-14 1.2e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail6.119.624.3-4.7-4.3-4.44.9-4.44.7-4.9-4.9-4.7-4.4-4.9-3.73.64.2-3.4
BMI without tail3.67.68.9-2.9-2.7-2.82.3-2.92.9-2.6-2.7-2.9-2.8-2.7-2.82.82.8-3.0
Body weight1.24.95.9-2.4-2.1-2.22.3-2.22.4-2.4-2.4-2.4-2.2-2.4-1.91.92.1-1.8
Epididymis fat weight0.10.30.70.60.50.6-0.80.5-0.60.70.70.60.50.70.3-0.3-0.5-0.0
Glucose1.62.43.5-1.5-1.6-1.61.7-1.51.5-1.7-1.9-1.5-1.6-1.9-1.31.31.5-1.0
Heart weight0.00.00.10.2-0.3-0.2-0.4-0.0-0.30.20.00.2-0.10.0-0.20.20.2-0.3
Left kidney weight0.10.30.50.50.70.4-0.20.7-0.60.40.50.50.60.50.6-0.6-0.60.5
Right kidney weight1.02.94.11.91.71.6-2.01.8-1.92.02.01.91.62.01.3-1.2-1.60.8
Tail length2.05.910.72.52.22.3-3.32.3-2.63.13.02.52.33.01.5-1.5-2.11.0
Length with tail1.76.48.12.62.52.6-2.72.5-2.72.82.82.62.52.82.2-2.1-2.42.0
Length without tail0.51.02.20.81.11.1-0.41.1-0.90.70.80.81.10.81.3-1.3-1.11.5
Liver weight, left1.93.13.7-1.9-1.7-1.71.9-1.81.9-1.9-1.9-1.9-1.7-1.9-1.61.61.7-1.4
Liver weight, right0.81.32.3-1.4-0.8-1.01.5-1.11.4-1.4-1.2-1.4-1.0-1.2-0.90.80.9-0.9
Parametrial fat weight0.10.20.80.50.30.3-0.90.4-0.50.70.60.50.30.60.2-0.2-0.3-0.1
Retroperitoneal fat weight0.30.91.4-0.9-0.9-1.00.8-1.01.0-0.9-0.9-0.9-0.9-0.9-0.90.90.9-1.2
Intraocular pressure0.91.22.1-0.7-1.5-1.30.2-1.10.7-0.7-0.9-0.7-1.3-0.9-1.41.41.4-1.3
Extensor digitorum longus weight5.220.924.8-5.0-4.4-4.44.3-4.74.9-4.5-4.7-5.0-4.5-4.7-4.34.34.5-4.3
Soleus weight7.822.829.1-5.3-4.4-4.65.4-4.85.2-5.3-5.1-5.3-4.6-5.1-4.14.04.5-3.5
Tibialis anterior weight0.93.24.4-2.1-1.6-1.61.9-1.82.0-1.9-1.9-2.1-1.7-1.9-1.61.61.7-1.5
Tibia length0.51.52.61.31.11.1-1.61.1-1.31.51.41.31.11.40.8-0.8-1.10.5
Number of licking bursts0.91.12.0-0.8-1.2-1.20.3-1.10.8-0.6-0.9-0.8-1.1-0.9-1.41.41.2-1.4
Food consumed during 24 hour testing period1.11.31.8-1.1-1.0-1.20.9-1.11.1-1.0-1.0-1.1-1.1-1.0-1.31.31.1-1.2
Times rat made contact with spout1.11.22.1-0.9-1.1-1.30.5-1.10.9-0.8-0.9-0.9-1.2-0.9-1.51.51.2-1.4
Mean time between licks in bursts2.53.56.12.21.51.6-2.51.8-2.22.32.02.21.62.01.4-1.3-1.51.1
Mean num. licks in bursts0.00.00.00.10.20.20.10.2-0.1-0.00.10.10.10.10.2-0.2-0.20.2
Std. dev. time between licks in bursts0.60.81.01.00.80.8-0.90.9-1.01.00.81.00.90.80.8-0.8-0.80.7
Water consumed over 24 hours0.30.30.7-0.7-0.2-0.40.9-0.40.7-0.7-0.6-0.7-0.4-0.6-0.40.40.3-0.3
Indifference point 0 sec0.10.10.3-0.3-0.2-0.20.6-0.20.3-0.4-0.4-0.3-0.2-0.40.0-0.00.1-0.2
Indifference point AUC0.40.50.80.80.50.6-0.90.7-0.80.80.70.80.60.70.5-0.5-0.60.6
Indifference point function ln k0.40.60.7-0.8-0.8-0.80.6-0.90.8-0.7-0.8-0.8-0.8-0.8-0.80.80.8-0.9
Indifference point function log k0.40.60.7-0.8-0.8-0.80.6-0.90.8-0.7-0.8-0.8-0.8-0.8-0.80.80.8-0.9
Delay discounting total patch changes 0 sec0.10.10.2-0.4-0.3-0.30.4-0.30.4-0.4-0.4-0.4-0.3-0.4-0.20.10.2-0.4
Delay discounting total patch changes 12 sec0.60.81.1-0.9-1.0-0.90.7-1.00.9-0.9-0.9-0.9-0.9-0.9-0.90.90.9-1.1
Delay discounting total patch changes 18 sec0.81.01.41.10.91.0-1.21.0-1.11.21.11.11.01.10.9-0.9-0.90.6
Delay discounting total patch changes 24 sec0.10.10.40.40.30.3-0.20.4-0.40.20.20.40.30.20.4-0.4-0.30.7
Delay discounting total patch changes 6 sec0.20.30.40.70.50.4-0.40.6-0.70.40.40.70.50.40.6-0.6-0.50.3
Delay discounting time to switch 0 sec0.30.41.3-0.20.80.70.90.40.2-0.40.1-0.20.60.10.8-0.8-0.71.1
Delay discounting water rate 0 sec1.52.46.0-1.1-1.8-1.70.2-1.61.2-0.7-1.2-1.1-1.7-1.2-1.91.91.8-2.5
Delay discounting water rate 12 sec3.95.87.2-2.2-2.6-2.71.5-2.62.3-2.0-2.3-2.2-2.6-2.3-2.62.62.7-2.6
Delay discounting water rate 18 sec2.83.78.9-1.3-2.3-2.10.1-2.01.4-0.9-1.4-1.3-2.1-1.4-2.52.52.3-3.0
Delay discounting water rate 24 sec4.25.810.6-2.0-2.8-2.60.9-2.62.0-1.6-2.1-2.0-2.7-2.1-2.82.92.8-3.3
Delay discounting water rate 6 sec0.71.02.5-0.6-1.2-1.2-0.3-1.00.6-0.2-0.6-0.6-1.1-0.6-1.41.51.3-1.6
Locomotor activity4.47.08.12.52.82.8-2.32.7-2.62.62.82.52.82.82.6-2.6-2.82.4
Locomotor testing distance2.33.84.41.92.02.1-1.72.0-1.91.92.11.92.02.11.9-1.9-2.01.7
Locomotor testing rearing0.10.20.3-0.3-0.5-0.5-0.0-0.50.3-0.1-0.3-0.3-0.5-0.3-0.60.60.5-0.6
Light reinforcement 17.413.514.93.93.53.7-3.63.7-3.93.73.83.93.63.83.4-3.4-3.53.7
Light reinforcement 22.93.94.92.11.82.0-1.72.0-2.11.81.92.11.91.92.0-1.9-1.92.2
Reaction time number correct2.53.65.8-1.6-2.0-2.10.9-2.01.7-1.4-1.7-1.6-2.0-1.7-2.32.32.1-2.4
Reaction time mean minus median0.10.20.70.60.20.3-0.80.4-0.60.70.40.60.20.40.1-0.1-0.2-0.2
Reaction time mean minus median AUC0.10.20.30.30.50.4-0.10.5-0.30.20.30.30.50.30.5-0.5-0.50.5
Reaction time num false alarms1.01.32.0-1.0-1.4-1.10.4-1.31.0-0.7-1.0-1.0-1.3-1.0-1.31.31.3-1.4
Reaction time num false alarms AUC1.31.93.0-1.2-1.6-1.30.5-1.51.2-0.9-1.2-1.2-1.5-1.2-1.61.61.6-1.7
Reaction time trials correct on left2.53.65.8-1.6-2.0-2.10.9-2.01.7-1.4-1.7-1.6-2.0-1.7-2.32.32.1-2.4
Reaction time trials on left2.43.45.4-1.6-2.0-2.00.9-1.91.6-1.3-1.7-1.6-2.0-1.7-2.22.22.0-2.3
Reaction time mean0.00.00.10.1-0.0-0.10.20.1-0.0-0.2-0.20.1-0.0-0.20.1-0.10.00.3
Reaction time mean AUC0.00.00.1-0.0-0.1-0.20.40.10.0-0.3-0.3-0.0-0.1-0.30.1-0.10.10.3
Median of all reaction times0.10.10.5-0.3-0.2-0.30.7-0.20.3-0.6-0.5-0.3-0.3-0.5-0.00.00.20.3
Reaction time omissions0.30.40.80.90.50.5-0.40.8-0.90.40.40.90.60.40.7-0.6-0.60.9
Reaction time false alarm rate0.00.10.1-0.3-0.3-0.10.2-0.40.3-0.2-0.3-0.3-0.3-0.3-0.20.20.3-0.2
Reaction time premature initiation rate0.20.31.00.80.20.2-1.00.5-0.80.80.50.80.30.50.2-0.2-0.20.3
Reaction time premature initiations0.30.41.00.0-0.9-0.8-0.6-0.50.00.1-0.30.0-0.8-0.3-1.01.00.9-1.0
Std. dev. reaction times0.00.00.10.40.00.0-0.30.3-0.40.30.10.40.10.10.1-0.1-0.1-0.0
Reaction time trials completed2.43.45.4-1.6-2.0-2.00.9-1.91.6-1.3-1.7-1.6-2.0-1.7-2.22.22.0-2.3
Reaction time trials AUC2.73.96.5-1.7-2.2-2.20.9-2.01.7-1.4-1.7-1.7-2.1-1.7-2.42.42.2-2.6
Social response proportion1.51.62.01.31.41.2-0.91.4-1.31.11.21.31.31.21.4-1.4-1.41.3
Social responses6.98.910.33.03.03.1-3.03.0-3.13.23.23.03.03.22.7-2.7-3.02.4
Social time0.20.20.8-0.6-0.3-0.30.9-0.40.6-0.7-0.6-0.6-0.3-0.6-0.00.00.30.1
Conditioned locomotion3.13.74.3-1.9-2.1-2.01.4-2.01.9-1.7-1.9-1.9-2.0-1.9-2.02.02.0-2.0
Cocaine response after cond. corrected10.011.212.4-3.4-3.5-3.52.7-3.53.4-3.1-3.3-3.4-3.5-3.3-3.53.53.5-3.3
Cocaine response after cond. not corrected10.411.512.7-3.4-3.5-3.52.7-3.63.4-3.2-3.3-3.4-3.5-3.3-3.53.53.6-3.4
Cocaine response before conditioning0.60.81.00.90.90.9-0.90.9-0.91.00.90.90.90.90.8-0.8-0.80.6
Saline control response0.10.10.2-0.3-0.4-0.40.3-0.30.3-0.3-0.5-0.3-0.4-0.5-0.20.20.4-0.3
Condit. Reinf. active minus inactive responses0.40.51.90.90.20.3-1.40.5-0.91.00.70.90.30.70.1-0.1-0.2-0.2
Condit. Reinf. active-inactive response ratio0.60.61.3-0.4-1.1-1.00.2-0.80.4-0.6-0.8-0.4-1.0-0.8-0.80.91.0-0.8
Condit. Reinf. active responses0.60.82.31.10.50.6-1.50.8-1.11.30.91.10.60.90.4-0.4-0.60.1
Condit. Reinf. inactive responses0.60.71.60.90.80.7-1.30.8-0.91.21.00.90.71.00.4-0.4-0.70.1
Condit. Reinf. lever presses0.71.02.71.20.60.7-1.60.8-1.21.41.11.20.71.10.5-0.5-0.60.3
Condit. Reinf. lever reinforcers received0.20.31.50.80.10.2-1.20.4-0.80.90.50.80.20.50.00.0-0.1-0.3
Pavlov. Cond. lever latency0.20.20.6-0.6-0.3-0.40.8-0.40.6-0.6-0.5-0.6-0.3-0.5-0.30.30.3-0.2
Pavlov. Cond. magazine entry latency0.20.30.60.60.50.5-0.80.5-0.60.70.60.60.50.60.3-0.3-0.40.2
Pavlov. Cond. change in total contacts0.10.20.50.60.10.2-0.70.4-0.60.50.30.60.20.30.2-0.2-0.20.2
Pavlov. Cond. index score0.20.30.80.70.30.4-0.90.5-0.70.70.50.70.40.50.2-0.2-0.30.1
Pavlov. Cond. latency score0.30.30.70.70.40.5-0.80.6-0.70.70.60.70.50.60.4-0.4-0.40.3
Pavlov. Cond. lever contacts0.10.10.60.50.00.1-0.80.2-0.50.60.30.50.10.3-0.00.0-0.0-0.2
Pavlov. Cond. magazine entry number0.40.51.0-0.8-0.6-0.71.0-0.70.8-0.9-0.8-0.8-0.7-0.8-0.50.50.6-0.3
Pavlov. Cond. intertrial magazine entries0.91.11.6-1.0-1.1-1.20.6-1.11.0-0.9-1.0-1.0-1.2-1.0-1.21.21.2-1.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.80.50.5-0.90.6-0.80.80.70.80.50.70.4-0.4-0.50.3
Pavlov. Cond. response bias0.40.61.81.00.40.5-1.40.6-1.01.10.81.00.50.80.3-0.2-0.40.0
Conditioned reinforcement - actives1.81.82.31.41.21.4-1.51.2-1.41.51.51.41.31.51.1-1.1-1.31.1
Conditioned reinforcement - inactives0.80.91.2-1.1-1.0-0.90.7-1.11.1-0.8-0.8-1.1-0.9-0.8-1.01.00.9-0.8
Conditioned locomotion5.76.99.02.82.42.6-3.02.5-2.83.02.92.82.52.92.1-2.1-2.42.2
Intermittent access intake day 1-15 change4.04.06.92.21.82.0-2.61.9-2.22.52.32.21.92.31.5-1.5-1.80.3
Intermittent access intake escalation2.42.36.11.71.11.3-2.51.3-1.72.11.91.71.21.90.8-0.7-1.1-0.6
Intermittent access intake escalation 23.03.07.22.01.31.5-2.71.5-2.02.32.12.01.42.10.9-0.9-1.3-0.4
Intermitt. access day 1 inactive lever presses0.20.20.7-0.3-0.5-0.3-0.2-0.50.30.0-0.1-0.3-0.4-0.1-0.60.70.5-0.9
Intermitt. access day 15 inactive lever presses0.20.20.60.50.30.4-0.80.3-0.50.70.60.50.40.60.2-0.2-0.40.0
Intermitt. access escalation Index0.20.10.70.10.40.20.40.4-0.1-0.1-0.00.10.3-0.00.5-0.5-0.30.9
Intermittent access day 1 total infusions0.10.10.7-0.2-0.00.00.2-0.10.2-0.1-0.0-0.2-0.0-0.0-0.00.00.00.8
Intermittent access day 15 total infusions0.80.92.31.00.70.9-1.50.8-1.01.31.21.00.91.20.5-0.5-0.80.4
Intermittent access terminal intake (last 3 days)0.60.71.20.80.70.9-1.10.6-0.81.11.10.80.81.10.6-0.6-0.80.5
Intermittent access total infusions0.10.10.20.20.20.3-0.50.1-0.20.40.40.20.20.40.1-0.1-0.20.4
Intermittent access day 1 locomotion0.20.30.50.50.40.5-0.70.4-0.50.70.60.50.40.60.3-0.3-0.40.5
Intermittent access day 15 total locomotion2.82.94.41.81.51.7-2.11.6-1.82.02.01.81.62.01.3-1.3-1.51.4
Intermittent access total locomotion1.01.11.41.01.01.1-1.10.9-1.01.11.21.01.01.20.9-0.9-1.01.2
Intermittent access standard deviation1.01.02.71.20.70.9-1.70.8-1.21.41.21.20.81.20.5-0.5-0.70.2
Cocaine induced anxiety1.82.02.91.31.61.5-0.81.5-1.31.11.31.31.51.31.7-1.7-1.61.7
Post-drug Anxiety1.82.03.41.31.51.5-0.81.5-1.31.11.31.31.51.31.6-1.6-1.51.9
Baseline Anxiety0.10.10.4-0.0-0.4-0.3-0.4-0.30.00.2-0.0-0.0-0.3-0.0-0.50.50.4-0.6
Lifetime Intake0.10.10.20.10.20.3-0.30.1-0.10.30.30.10.20.30.1-0.1-0.20.4
Incentive Sensitization - Responses0.10.10.9-0.2-0.3-0.2-0.2-0.30.20.0-0.0-0.2-0.3-0.0-0.40.40.3-0.9
Incentive Sensitization - Breakpoint0.10.10.6-0.1-0.2-0.1-0.3-0.20.10.10.1-0.1-0.10.1-0.30.30.1-0.8
Progressive ratio test 1 active lever presses0.30.30.5-0.5-0.6-0.60.1-0.60.5-0.3-0.4-0.5-0.6-0.4-0.70.70.6-0.3
Progressive ratio test 1 breakpoint0.30.30.5-0.6-0.7-0.60.2-0.70.6-0.4-0.5-0.6-0.6-0.5-0.70.70.7-0.4
Progressive ratio test 1 inactive lever presses0.00.00.10.20.20.2-0.30.1-0.20.30.30.20.20.30.1-0.1-0.20.3
Progressive ratio test 2 active lever presses0.10.10.3-0.1-0.3-0.2-0.3-0.30.10.10.0-0.1-0.20.0-0.40.40.3-0.5
Progressive ratio test 2 breakpoint0.00.00.20.20.10.2-0.40.1-0.20.30.30.20.20.30.0-0.0-0.1-0.1
Progressive ratio test 2 inactive lever presses0.10.20.30.20.40.5-0.20.3-0.20.30.50.20.50.50.4-0.4-0.50.5
Total sessions with >9 infusions0.00.00.2-0.00.20.20.10.10.0-0.00.1-0.00.20.10.2-0.2-0.20.5
Short access day 1 total inactive lever presses0.20.20.30.30.40.5-0.40.3-0.30.40.50.30.50.50.3-0.3-0.50.5
Short access day 10 total inactive lever presses0.00.00.1-0.2-0.2-0.10.0-0.20.2-0.1-0.1-0.2-0.2-0.1-0.30.30.2-0.4
Short access day 1 total infusions0.90.91.50.81.11.1-0.50.9-0.80.81.00.81.11.01.1-1.1-1.11.2
Short access day 10 total infusions0.00.00.1-0.2-0.3-0.2-0.3-0.30.20.1-0.0-0.2-0.2-0.0-0.40.40.30.0
Short access total infusions0.00.00.10.00.20.2-0.00.1-0.00.10.20.00.20.20.2-0.2-0.20.4
Short access day 1 locomotion1.41.51.91.21.31.4-1.11.2-1.21.21.41.21.31.41.2-1.2-1.31.1
Short access day 10 total locomotion1.92.14.21.71.21.3-2.11.4-1.71.91.71.71.31.71.0-1.0-1.20.6
Short access total locomotion0.80.81.00.90.91.0-1.00.8-0.91.01.00.90.91.00.8-0.8-0.90.9
Compulsive drug intake0.50.51.5-0.8-0.4-0.51.2-0.50.8-1.0-0.9-0.8-0.5-0.9-0.20.20.40.1
One hour access (0.3 mA shock)0.10.20.3-0.5-0.5-0.40.4-0.50.5-0.4-0.4-0.5-0.4-0.4-0.30.30.40.1
One hour access (shock baseline)0.10.10.2-0.2-0.5-0.3-0.4-0.40.20.1-0.1-0.2-0.4-0.1-0.50.50.4-0.3
Number of responses in last shaping day0.10.10.20.20.30.4-0.40.2-0.20.40.40.20.30.40.2-0.2-0.30.3
Context. condit. distance diff. score0.30.30.7-0.7-0.4-0.30.3-0.60.7-0.3-0.3-0.7-0.5-0.3-0.70.70.5-0.9
Locomotion velocity, session 11.81.92.91.31.51.4-0.71.5-1.31.01.21.31.51.21.6-1.6-1.51.7
Locomotion distance, session 13.03.95.91.42.42.3-0.82.0-1.41.41.81.42.31.82.4-2.4-2.32.3
Locomotion velocity, session 28.810.312.33.03.53.5-2.63.3-3.03.13.33.03.53.33.3-3.3-3.53.1
Locomotion distance, session 25.47.711.52.53.02.9-1.52.9-2.52.12.42.53.02.43.3-3.3-3.13.4
Locomotion velocity, session 34.45.19.12.52.02.1-3.02.2-2.52.82.52.52.12.51.6-1.6-1.91.2
Locomotion distance, session 30.10.10.2-0.2-0.3-0.3-0.1-0.30.2-0.0-0.2-0.2-0.3-0.2-0.30.40.3-0.5
Stereotopy head waving bouts, day 36.17.38.82.82.72.7-2.92.8-2.83.02.82.82.72.82.4-2.4-2.62.1
Stereotopy head waving duration, day 35.97.29.22.92.62.6-3.02.7-2.93.02.92.92.62.92.2-2.2-2.51.9
Locomotion velocity, session 70.30.31.00.40.50.6-1.00.3-0.40.90.80.40.50.80.1-0.0-0.4-0.3
Locomotion distance, session 70.91.12.3-1.0-1.1-1.10.4-1.11.0-0.7-0.8-1.0-1.1-0.8-1.41.41.2-1.5
Stereotopy head waving bouts, day 70.70.81.30.71.01.0-0.30.9-0.70.60.70.71.00.71.1-1.1-1.01.1
Stereotopy head waving duration, day 71.31.52.41.11.41.4-0.61.3-1.10.91.01.11.41.01.5-1.5-1.41.5
Locomotion velocity, session 82.83.34.61.62.22.1-1.21.9-1.61.61.71.62.01.72.0-2.0-2.11.9
Locomotion distance, session 80.91.31.90.91.31.4-0.81.1-0.91.01.20.91.31.21.2-1.2-1.31.1
Degree of sensitization distance0.30.30.5-0.7-0.4-0.50.6-0.60.7-0.5-0.4-0.7-0.5-0.4-0.60.60.5-0.6
Degree of sensitization stereotypy0.60.72.0-1.0-0.6-0.61.4-0.71.0-1.2-1.0-1.0-0.6-1.0-0.20.20.50.0
Condit. Reinf. active minus inactive responses4.14.56.42.31.92.1-2.52.1-2.32.52.42.32.02.41.7-1.7-2.01.4
Condit. Reinf. active-inactive response ratio0.80.92.31.20.60.7-1.50.8-1.21.31.11.20.71.10.5-0.5-0.60.3
Condit. Reinf. active responses5.97.18.22.62.72.9-2.52.7-2.62.72.82.62.82.82.6-2.6-2.72.4
Condit. Reinf. inactive responses3.33.95.31.72.22.3-1.22.0-1.71.61.81.72.21.82.3-2.3-2.22.3
Incentive salience index mean3.94.75.42.12.22.3-2.12.2-2.12.22.32.12.22.32.1-2.1-2.21.9
Condit. Reinf. lever presses1.92.54.91.11.91.8-0.31.6-1.10.91.21.11.81.22.1-2.1-1.92.2
Time in familiar zone, hab. session 10.90.92.21.10.70.7-1.50.8-1.11.21.31.10.71.30.3-0.3-0.60.2
Time in novel zone, hab. session 10.30.31.1-0.6-0.2-0.21.1-0.30.6-0.8-0.7-0.6-0.2-0.70.1-0.10.10.2
Total zone transitions, hab. session 13.04.25.41.92.32.1-1.32.2-1.91.71.91.92.21.92.3-2.3-2.32.3
Total locomotion distance, hab. session 14.26.18.32.12.92.7-1.62.6-2.12.12.42.12.72.42.8-2.8-2.82.6
Locomotion velocity, hab. session 14.86.99.02.33.02.9-1.92.7-2.32.42.62.32.92.62.8-2.8-2.92.7
Time in familiar zone, hab. session 23.03.16.72.11.31.5-2.61.6-2.12.22.12.11.42.10.9-0.9-1.30.7
Time in novel zone, hab. session 22.32.45.1-1.8-1.1-1.32.3-1.41.8-2.0-1.8-1.8-1.2-1.8-1.00.91.1-0.8
Total zone transitions, hab. session 21.62.04.40.91.81.50.11.6-0.90.60.90.91.70.92.0-2.0-1.82.1
Total locomotion distance, hab. session 23.74.96.62.02.62.3-1.42.4-2.01.92.12.02.52.12.4-2.4-2.52.3
Locomotion velocity, hab. session 24.56.08.32.22.92.5-1.42.7-2.22.02.32.22.72.32.7-2.7-2.82.7
Novel to familiar place preference ratio1.51.54.7-1.5-0.7-0.92.2-1.01.5-1.8-1.6-1.5-0.8-1.6-0.30.30.7-0.0
Novelty place preference0.70.72.7-1.0-0.4-0.51.7-0.61.0-1.3-1.1-1.0-0.5-1.1-0.10.00.40.2
Time in novel zone, NPP test1.01.03.1-1.2-0.6-0.71.8-0.81.2-1.4-1.2-1.2-0.7-1.2-0.30.30.6-0.1
Total zone transitions, NPP test1.21.73.71.01.51.3-0.11.4-1.00.60.91.01.40.91.8-1.8-1.51.9
Total locomotion distance, NPP test1.11.52.80.81.51.3-0.21.3-0.80.70.90.81.40.91.6-1.7-1.51.7
Locomotion velocity, NPP test1.42.03.61.11.71.5-0.41.5-1.10.91.11.11.61.11.9-1.9-1.71.9
Pavlov. Cond. lever latency0.70.91.7-0.5-1.3-1.30.4-0.90.5-0.8-1.0-0.5-1.2-1.0-1.11.11.2-0.9
Pavlov. Cond. magazine entry latency3.03.86.02.01.92.0-2.51.8-2.02.42.32.01.92.31.5-1.4-1.81.1
Pavlov. Cond. change in total contacts0.40.40.70.40.80.8-0.70.5-0.40.80.80.40.70.80.4-0.4-0.70.2
Pavlov. Cond. index score1.52.02.81.11.71.7-1.31.3-1.11.51.61.11.51.61.3-1.3-1.51.0
Pavlov. Cond. latency score2.02.53.81.31.91.9-1.31.6-1.31.61.71.31.81.71.6-1.6-1.81.3
Pavlov. Cond. lever contacts1.31.52.60.81.61.5-0.61.2-0.81.01.20.81.51.21.4-1.4-1.51.3
Pavlov. Cond. magazine entry number1.11.42.0-1.2-1.2-1.31.4-1.11.2-1.4-1.4-1.2-1.2-1.4-0.90.91.1-0.7
Pavlov. Cond. intertrial magazine entries0.20.20.5-0.1-0.6-0.5-0.2-0.40.1-0.1-0.2-0.1-0.5-0.2-0.70.70.6-0.7
Pavlov. Cond. lever-magazine prob. diff.2.02.53.31.41.81.8-1.51.5-1.41.71.81.41.71.81.4-1.4-1.71.1
Pavlov. Cond. response bias1.62.02.81.31.51.5-1.61.3-1.31.71.61.31.41.61.1-1.1-1.40.8
Bone: apparent density1.22.05.60.91.61.60.31.4-0.90.41.00.91.51.01.9-1.9-1.72.4
Bone surface3.35.912.51.92.82.6-0.42.5-1.91.32.01.92.72.03.1-3.1-2.83.5
Bone volume3.15.211.51.72.62.5-0.32.4-1.71.11.91.72.51.92.9-2.9-2.73.4
Bone: connectivity density0.50.82.70.41.00.90.60.8-0.4-0.00.50.40.90.51.2-1.3-1.11.6
Bone: cortical apparent density0.91.21.8-1.0-1.0-1.31.3-1.01.0-1.3-1.2-1.0-1.1-1.2-0.90.91.0-0.6
Bone: cortical area0.10.20.8-0.5-0.0-0.20.9-0.20.5-0.6-0.4-0.5-0.2-0.40.0-0.00.10.3
Bone: cortical porosity1.01.11.61.01.11.2-0.71.1-1.00.91.01.01.11.01.2-1.2-1.11.2
Bone: cortical porosity0.80.91.90.71.01.1-0.20.9-0.70.50.70.71.00.71.3-1.3-1.11.4
Bone: cortical thickness0.50.82.1-1.1-0.7-0.81.5-0.81.1-1.3-1.1-1.1-0.8-1.1-0.50.50.7-0.2
Bone: cortical thickness0.70.81.6-0.7-1.1-1.00.2-1.00.7-0.5-0.7-0.7-1.0-0.7-1.11.11.1-1.3
Bone: cortical tissue density0.70.91.4-0.8-0.9-1.21.1-0.80.8-1.2-1.1-0.8-1.0-1.1-0.80.80.9-0.6
Bone: elastic displacement0.10.10.30.30.20.3-0.20.3-0.30.20.30.30.30.30.4-0.4-0.30.5
Bone: elastic work0.20.30.6-0.7-0.5-0.50.8-0.60.7-0.7-0.5-0.7-0.5-0.5-0.40.40.5-0.2
Bone: endosteal estimation0.10.20.4-0.6-0.3-0.40.5-0.50.6-0.4-0.4-0.6-0.4-0.4-0.40.40.4-0.4
Bone: endosteal perimeter0.51.11.41.01.21.2-0.91.1-1.01.01.11.01.11.11.1-1.1-1.11.0
Bone: final force0.71.22.1-1.4-0.8-0.91.4-1.11.4-1.3-1.1-1.4-0.9-1.1-0.80.80.9-0.7
Bone: final moment0.60.91.7-1.2-0.7-0.81.3-1.01.2-1.2-1.0-1.2-0.8-1.0-0.70.70.8-0.6
Bone: marrow area0.10.20.4-0.6-0.3-0.40.5-0.50.6-0.4-0.4-0.6-0.4-0.4-0.40.40.4-0.5
Bone: maximum diameter1.42.63.11.61.81.7-1.21.7-1.61.51.61.61.71.61.7-1.7-1.71.7
Bone: maximum force1.01.72.5-1.6-1.1-1.11.5-1.31.6-1.4-1.3-1.6-1.2-1.3-1.11.11.1-1.0
Bone: maximum moment0.81.42.0-1.4-1.0-1.01.4-1.21.4-1.3-1.2-1.4-1.1-1.2-1.00.91.0-0.9
Bone: minimum diameter0.00.10.20.10.40.3-0.10.2-0.10.20.20.10.30.20.3-0.3-0.30.2
Bone: periosteal estimation0.00.10.4-0.40.1-0.00.7-0.20.4-0.4-0.2-0.4-0.1-0.20.1-0.10.00.2
Bone: periosteal perimeter0.40.71.00.61.00.9-0.30.8-0.60.60.70.60.90.71.0-1.0-0.91.0
Bone: post-yield work0.71.01.7-1.1-0.9-0.90.7-1.11.1-0.7-0.9-1.1-1.0-0.9-1.11.11.0-1.3
Bone: stiffness1.82.94.1-2.0-1.4-1.52.0-1.72.0-1.9-1.8-2.0-1.5-1.8-1.41.41.5-1.3
Bone: tissue strength1.01.02.0-1.1-0.8-0.81.4-0.91.1-1.3-1.1-1.1-0.8-1.1-0.60.60.8-0.4
Bone: trabecular number2.13.34.51.62.02.0-1.01.9-1.61.41.81.62.01.82.0-2.0-2.02.1
Bone: trabecular spacing3.84.98.9-1.9-2.5-2.40.8-2.31.9-1.4-1.9-1.9-2.4-1.9-2.72.72.5-3.0
Bone: trabecular thickness3.03.69.71.32.22.00.22.0-1.30.61.41.32.11.42.5-2.5-2.33.1
Bone: trabecular tissue density1.92.73.0-1.7-1.5-1.71.5-1.71.7-1.6-1.6-1.7-1.6-1.6-1.61.61.6-1.6
Breakpoint value in progressive ratio session3.13.56.52.11.51.7-2.61.8-2.12.32.12.11.72.11.3-1.2-1.51.0
Distance traveled before self-admin0.20.20.7-0.4-0.2-0.30.8-0.30.5-0.7-0.4-0.4-0.3-0.4-0.20.20.2-0.2
Distance traveled after self-admin0.70.81.00.81.00.9-0.80.9-0.90.91.00.80.91.00.8-0.8-0.90.7
Delta time in closed arm before/after self-admin4.44.38.1-1.8-2.3-2.21.0-2.21.8-1.5-1.8-1.8-2.2-1.8-2.42.42.3-2.8
Delta time in open arm before/after self-admin0.50.51.3-0.8-0.5-0.51.1-0.60.8-1.0-0.8-0.8-0.5-0.8-0.40.40.5-0.0
Diff in mean of infusions in LGA sessions1.61.72.51.41.21.4-1.61.4-1.51.61.31.41.31.31.0-1.0-1.21.0
Extinction: sum of active levers before priming0.30.31.20.60.30.5-1.10.4-0.60.90.70.60.40.70.1-0.1-0.30.1
Active lever presses in extinction session 62.42.32.71.51.51.5-1.61.6-1.61.61.61.51.51.61.4-1.4-1.51.5
Delta distance traveled before/after self-admin1.51.62.41.21.21.3-1.51.3-1.41.51.41.21.31.41.1-1.1-1.21.1
Delta ambulatory time before/after self-admin1.92.12.81.41.41.5-1.61.4-1.51.71.51.41.51.51.3-1.3-1.41.2
Time in closed arm before self-admin0.20.20.5-0.10.50.50.70.40.1-0.3-0.2-0.10.4-0.20.7-0.7-0.50.7
Time in closed arm after self-admin0.00.00.5-0.0-0.1-0.0-0.1-0.0-0.00.0-0.1-0.0-0.1-0.1-0.10.10.1-0.7
Time in open arm before self-admin0.30.30.80.60.40.3-0.90.4-0.60.80.70.60.40.70.3-0.3-0.30.4
Time in open arm after self-admin0.80.91.1-1.0-0.9-1.01.0-0.91.0-1.1-0.9-1.0-0.9-0.9-0.80.80.9-0.5
Sum of active levers in priming session hrs 5-60.00.00.20.00.20.20.00.1-0.10.00.10.00.20.10.2-0.2-0.20.5
Time to tail flick, vehicle, before self-admin1.61.64.81.11.31.3-0.71.3-1.11.01.11.11.31.11.3-1.3-1.32.2
Time to tail flick, vehicle, after self-admin0.20.21.6-0.1-0.5-0.4-0.4-0.50.20.10.0-0.1-0.40.0-0.60.60.5-1.3
Time to tail flick, test, before self-admin1.01.02.10.81.01.0-0.41.0-0.80.70.80.81.00.81.2-1.2-1.11.4
Time to tail flick, test, after self-admin0.60.60.80.90.80.8-0.60.8-0.80.70.80.90.80.80.8-0.8-0.80.1
Delta time to tail flick, vehicle, before/after SA2.12.18.0-1.1-1.5-1.40.6-1.51.3-0.9-0.9-1.1-1.5-0.9-1.61.61.5-2.8
Delta time to tail flick, test, before/after SA0.20.21.80.1-0.3-0.1-0.4-0.2-0.00.20.00.1-0.20.0-0.50.50.3-1.3
Ambulatory time before self-admin0.20.20.7-0.5-0.3-0.40.8-0.30.5-0.7-0.5-0.5-0.4-0.5-0.20.20.3-0.1
Ambulatory time after self-admin0.40.50.60.60.80.7-0.50.7-0.70.60.80.60.70.80.6-0.6-0.70.6
Total heroin consumption1.82.12.51.61.31.4-1.61.4-1.61.61.61.61.41.61.3-1.2-1.41.4
Area under the delay curve1.81.92.7-1.6-1.3-1.31.6-1.41.6-1.6-1.4-1.6-1.3-1.4-1.21.21.3-0.7
Delay disc. indifference point, 0s delay1.82.07.6-1.7-0.6-0.82.8-1.01.7-2.1-1.7-1.7-0.8-1.7-0.10.10.60.6
Delay disc. indifference point, 16s delay0.10.10.1-0.3-0.4-0.30.4-0.30.3-0.4-0.3-0.3-0.3-0.3-0.40.40.3-0.1
Delay disc. indifference point, 2s delay3.03.36.4-2.1-1.4-1.62.5-1.72.1-2.3-2.2-2.1-1.6-2.2-1.21.11.5-0.5
Delay disc. indifference point, 24s delay1.21.21.4-1.1-1.1-1.21.1-1.11.1-1.1-1.2-1.1-1.1-1.2-1.11.11.1-0.8
Delay disc. indifference point, 4s delay0.40.40.9-0.8-0.5-0.51.0-0.60.8-0.8-0.7-0.8-0.5-0.7-0.40.40.50.1
Delay disc. indifference point, 8s delay2.12.22.7-1.6-1.5-1.41.3-1.61.6-1.4-1.2-1.6-1.5-1.2-1.61.61.5-1.4
Delay discount exponential model param1.92.02.51.61.31.3-1.61.5-1.61.61.41.61.41.41.3-1.3-1.30.7
Delay discount hyperbolic model param2.42.53.51.81.51.5-1.91.6-1.81.81.61.81.51.61.4-1.4-1.50.8
Fecal boli incidents, locomotor time 11.71.82.5-1.6-1.2-1.21.4-1.41.6-1.4-1.2-1.6-1.3-1.2-1.31.31.3-1.3
Change in fecal boli incidents, locomotor task0.10.10.20.40.40.4-0.30.4-0.40.40.30.40.40.30.4-0.4-0.40.4
Time >=10cm from walls, locomotor time 10.10.10.9-0.40.20.10.9-0.00.4-0.6-0.3-0.40.1-0.30.2-0.3-0.2-0.1
Bouts of movement, locomotor time 10.10.10.40.20.20.2-0.60.1-0.20.50.40.20.20.4-0.10.1-0.1-0.4
Total resting periods, locomotor time 10.20.20.50.40.40.4-0.70.3-0.40.60.60.40.40.60.1-0.1-0.3-0.2
Rest time, locomotor task time 10.60.71.20.71.01.0-0.90.8-0.71.01.10.70.91.10.6-0.6-0.9-0.1
Distance moved, locomotor task time 10.20.21.1-0.3-0.1-0.11.0-0.10.3-0.8-0.5-0.3-0.1-0.50.3-0.3-0.00.6
Vertical activity count, locomotor time 11.01.11.7-0.9-1.3-1.20.9-1.10.9-1.1-1.1-0.9-1.2-1.1-1.11.11.2-0.6
Time >=10cm from walls, locomotor time 22.32.53.1-1.7-1.5-1.51.5-1.61.7-1.6-1.5-1.7-1.5-1.5-1.61.51.5-1.8
Bouts of movement, locomotor time 21.71.93.01.31.51.4-0.81.5-1.31.11.21.31.51.21.5-1.5-1.51.7
Total resting periods, locomotor time 21.71.82.91.31.51.4-0.81.5-1.31.11.21.31.51.21.5-1.5-1.51.7
Rest time, locomotor task time 21.01.21.61.11.21.2-0.91.2-1.11.11.11.11.21.11.0-1.0-1.20.8
Distance moved, locomotor task time 20.91.11.2-1.1-1.1-1.11.0-1.11.1-1.0-1.1-1.1-1.1-1.1-0.90.91.1-0.8
Vertical activity count, locomotor time 21.92.02.5-1.5-1.5-1.41.0-1.61.5-1.2-1.2-1.5-1.5-1.2-1.61.61.6-1.5
Weight adjusted by age1.82.03.0-1.2-1.5-1.40.8-1.41.2-1.1-1.3-1.2-1.5-1.3-1.61.61.6-1.7
Seeking ratio, delayed vs. immediate footshock4.24.85.82.42.12.1-2.32.2-2.42.42.32.42.12.31.9-1.8-2.12.0
Locomotion in novel chamber0.10.10.80.3-0.2-0.3-0.3-0.1-0.10.1-0.00.3-0.3-0.0-0.40.40.3-0.9
Locomotion in novel chamber post-restriction0.30.41.30.70.40.4-1.10.4-0.70.90.80.70.40.80.1-0.1-0.3-0.5
Progressive ratio0.10.20.7-0.4-0.3-0.30.2-0.50.5-0.3-0.2-0.4-0.3-0.2-0.40.40.3-0.8
Food seeking constrained by brief footshock0.91.11.70.91.31.3-0.91.1-0.91.11.30.91.21.30.9-0.9-1.20.7
Seeking ratio, punishment vs. effort0.60.81.20.81.01.0-0.61.0-0.90.80.90.81.00.90.8-0.8-1.01.1
Run reversals in cocaine runway, females0.50.50.70.60.80.7-0.80.7-0.60.80.90.60.70.90.6-0.6-0.70.2
Run reversals in cocaine runway, males2.01.92.21.51.41.4-1.31.4-1.51.41.51.51.41.51.3-1.3-1.41.0
Latency to leave start box in cocaine runway1.71.93.31.41.31.3-0.51.5-1.40.91.01.41.41.01.8-1.8-1.51.8
Latency to leave start box in cocaine runway, F0.91.03.50.61.00.80.51.0-0.6-0.00.30.61.00.31.6-1.6-1.11.9
Latency to leave start box in cocaine runway, M0.80.72.61.00.40.6-1.60.6-1.01.30.91.00.50.90.2-0.2-0.4-0.5
Cd content in liver0.20.20.4-0.4-0.4-0.40.6-0.40.4-0.6-0.6-0.4-0.4-0.6-0.10.10.30.1
Co content in liver0.30.40.80.60.50.6-0.90.6-0.70.80.70.60.60.70.4-0.4-0.50.3
Cu content in liver0.20.20.80.10.70.60.20.4-0.10.10.30.10.60.30.7-0.7-0.60.9
Fe content in liver0.00.10.3-0.1-0.00.2-0.4-0.10.00.30.2-0.1-0.00.2-0.20.20.1-0.6
K content in liver0.70.71.30.51.11.1-0.31.0-0.60.60.70.51.00.71.1-1.1-1.10.9
Mg content in liver0.60.71.30.51.00.9-0.10.9-0.60.50.50.50.90.51.1-1.1-1.01.0
Mn content in liver4.14.76.31.82.52.5-1.32.2-1.81.82.11.82.42.12.4-2.4-2.42.4
Na content in liver0.20.20.4-0.40.50.50.60.10.4-0.2-0.1-0.40.3-0.10.5-0.5-0.40.5
Rb content in liver0.20.20.7-0.00.50.40.50.4-0.0-0.20.0-0.00.40.00.7-0.7-0.50.8
Se content in liver0.50.61.00.60.91.0-0.90.7-0.61.01.00.60.81.00.6-0.6-0.80.3
Sr content in liver0.40.30.7-0.4-0.7-0.6-0.0-0.60.4-0.2-0.4-0.4-0.7-0.4-0.80.80.7-0.8
Zn content in liver0.30.31.40.5-0.3-0.2-1.20.1-0.60.70.40.5-0.20.4-0.50.50.3-0.7