Hub : Genes

Bsg

Models

#	tissue	modality	RNA phenotype	h²	h² se	h² P	eQTL R²	BLUP R²	ENET R²	LASSO R²	eQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000008414	0.5400	0.1800	0.0e+00	0.290	0.282	0.288	0.286	1.9e-32	2.0e-31	3.3e-32	5.6e-32
2	BLA	gene expression	ENSRNOG00000008414	0.4141	0.2033	1.9e-07	0.124	0.136	0.140	0.135	3.8e-07	1.0e-07	6.2e-08	1.0e-07
3	Brain	gene expression	ENSRNOG00000008414	0.4500	0.1500	0.0e+00	0.261	0.263	0.269	0.268	3.6e-24	2.2e-24	6.0e-25	7.6e-25
4	Brain	mRNA stability	ENSRNOG00000008414	0.0428	0.0327	1.9e-04	0.025	0.033	0.026	0.027	2.1e-03	4.7e-04	1.7e-03	1.4e-03
5	IL	alternative polyA	ENSRNOT00000011275	0.4680	0.2160	3.3e-03	0.014	0.032	0.043	0.041	1.4e-01	5.8e-02	3.4e-02	3.8e-02
6	IL	alternative polyA	ENSRNOT00000098215	0.4010	0.2240	5.0e-03	0.066	0.031	0.045	0.031	1.2e-02	6.1e-02	3.2e-02	6.1e-02
7	IL	gene expression	ENSRNOG00000008414	0.2530	0.1800	1.7e-03	0.053	0.086	0.073	0.070	2.1e-02	4.4e-03	8.1e-03	9.2e-03
8	LHb	gene expression	ENSRNOG00000008414	0.1854	0.1422	2.3e-03	0.093	0.083	-0.001	0.074	3.3e-03	5.3e-03	3.5e-01	8.0e-03
9	Liver	gene expression	ENSRNOG00000008414	0.3400	0.1600	0.0e+00	0.182	0.170	0.175	0.177	9.2e-20	1.6e-18	5.1e-19	2.8e-19
10	NAcc	gene expression	ENSRNOG00000008414	0.1900	0.1100	2.4e-06	0.081	0.084	0.081	0.079	1.3e-06	8.0e-07	1.2e-06	1.6e-06
11	OFC	gene expression	ENSRNOG00000008414	0.5413	0.2072	2.7e-07	0.287	0.257	0.270	0.257	1.5e-07	8.3e-07	4.0e-07	8.4e-07
12	PL	alternative TSS	ENSRNOT00000011275	0.1100	0.0860	7.5e-03	0.019	0.031	0.033	0.027	1.2e-02	1.9e-03	1.5e-03	3.5e-03
13	PL	alternative TSS	ENSRNOT00000105142	0.1200	0.0890	7.7e-03	0.017	0.031	0.033	0.027	1.7e-02	2.1e-03	1.5e-03	3.9e-03
14	PL	alternative TSS	ENSRNOT00000105142	0.0950	0.0770	7.6e-03	0.030	0.034	0.033	0.032	2.2e-03	1.3e-03	1.4e-03	1.8e-03
15	PL	gene expression	ENSRNOG00000008414	0.5089	0.2291	1.0e-13	0.158	0.178	0.185	0.180	4.6e-12	1.7e-13	4.8e-14	1.2e-13

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method.

Trait associations

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Cocaine response after cond. not corrected	10.4	11.5	12.7	-3.4	-3.5	-3.5	2.7	-3.6	3.4	-3.2	-3.3	-3.4	-3.5	-3.3	-3.5	3.5	3.6	-3.4
Cocaine response after cond. corrected	10.0	11.2	12.4	-3.4	-3.5	-3.5	2.7	-3.5	3.4	-3.1	-3.3	-3.4	-3.5	-3.3	-3.5	3.5	3.5	-3.3
Locomotion velocity, session 2	8.8	10.3	12.3	3.0	3.5	3.5	-2.6	3.3	-3.0	3.1	3.3	3.0	3.5	3.3	3.3	-3.3	-3.5	3.1
Soleus weight	7.8	22.8	29.1	-5.3	-4.4	-4.6	5.4	-4.8	5.2	-5.3	-5.1	-5.3	-4.6	-5.1	-4.1	4.0	4.5	-3.5
Light reinforcement 1	7.4	13.5	14.9	3.9	3.5	3.7	-3.6	3.7	-3.9	3.7	3.8	3.9	3.6	3.8	3.4	-3.4	-3.5	3.7
Social responses	6.9	8.9	10.3	3.0	3.0	3.1	-3.0	3.0	-3.1	3.2	3.2	3.0	3.0	3.2	2.7	-2.7	-3.0	2.4
BMI with tail	6.1	19.6	24.3	-4.7	-4.3	-4.4	4.9	-4.4	4.7	-4.9	-4.9	-4.7	-4.4	-4.9	-3.7	3.6	4.2	-3.4
Stereotopy head waving bouts, day 3	6.1	7.3	8.8	2.8	2.7	2.7	-2.9	2.8	-2.8	3.0	2.8	2.8	2.7	2.8	2.4	-2.4	-2.6	2.1
Stereotopy head waving duration, day 3	5.9	7.2	9.2	2.9	2.6	2.6	-3.0	2.7	-2.9	3.0	2.9	2.9	2.6	2.9	2.2	-2.2	-2.5	1.9
Condit. Reinf. active responses	5.9	7.1	8.2	2.6	2.7	2.9	-2.5	2.7	-2.6	2.7	2.8	2.6	2.8	2.8	2.6	-2.6	-2.7	2.4
Conditioned locomotion	5.7	6.9	9.0	2.8	2.4	2.6	-3.0	2.5	-2.8	3.0	2.9	2.8	2.5	2.9	2.1	-2.1	-2.4	2.2
Locomotion distance, session 2	5.4	7.7	11.5	2.5	3.0	2.9	-1.5	2.9	-2.5	2.1	2.4	2.5	3.0	2.4	3.3	-3.3	-3.1	3.4
Extensor digitorum longus weight	5.2	20.9	24.8	-5.0	-4.4	-4.4	4.3	-4.7	4.9	-4.5	-4.7	-5.0	-4.5	-4.7	-4.3	4.3	4.5	-4.3
Locomotion velocity, hab. session 1	4.8	6.9	9.0	2.3	3.0	2.9	-1.9	2.7	-2.3	2.4	2.6	2.3	2.9	2.6	2.8	-2.8	-2.9	2.7
Locomotion velocity, hab. session 2	4.5	6.0	8.3	2.2	2.9	2.5	-1.4	2.7	-2.2	2.0	2.3	2.2	2.7	2.3	2.7	-2.7	-2.8	2.7
Locomotor activity	4.4	7.0	8.1	2.5	2.8	2.8	-2.3	2.7	-2.6	2.6	2.8	2.5	2.8	2.8	2.6	-2.6	-2.8	2.4
Locomotion velocity, session 3	4.4	5.1	9.1	2.5	2.0	2.1	-3.0	2.2	-2.5	2.8	2.5	2.5	2.1	2.5	1.6	-1.6	-1.9	1.2
Delta time in closed arm before/after self-admin	4.4	4.3	8.1	-1.8	-2.3	-2.2	1.0	-2.2	1.8	-1.5	-1.8	-1.8	-2.2	-1.8	-2.4	2.4	2.3	-2.8
Delay discounting water rate 24 sec	4.2	5.8	10.6	-2.0	-2.8	-2.6	0.9	-2.6	2.0	-1.6	-2.1	-2.0	-2.7	-2.1	-2.8	2.9	2.8	-3.3
Total locomotion distance, hab. session 1	4.2	6.1	8.3	2.1	2.9	2.7	-1.6	2.6	-2.1	2.1	2.4	2.1	2.7	2.4	2.8	-2.8	-2.8	2.6
Seeking ratio, delayed vs. immediate footshock	4.2	4.8	5.8	2.4	2.1	2.1	-2.3	2.2	-2.4	2.4	2.3	2.4	2.1	2.3	1.9	-1.8	-2.1	2.0
Condit. Reinf. active minus inactive responses	4.1	4.5	6.4	2.3	1.9	2.1	-2.5	2.1	-2.3	2.5	2.4	2.3	2.0	2.4	1.7	-1.7	-2.0	1.4
Mn content in liver	4.1	4.7	6.3	1.8	2.5	2.5	-1.3	2.2	-1.8	1.8	2.1	1.8	2.4	2.1	2.4	-2.4	-2.4	2.4
Intermittent access intake day 1-15 change	4.0	4.0	6.9	2.2	1.8	2.0	-2.6	1.9	-2.2	2.5	2.3	2.2	1.9	2.3	1.5	-1.5	-1.8	0.3
Delay discounting water rate 12 sec	3.9	5.8	7.2	-2.2	-2.6	-2.7	1.5	-2.6	2.3	-2.0	-2.3	-2.2	-2.6	-2.3	-2.6	2.6	2.7	-2.6
Incentive salience index mean	3.9	4.7	5.4	2.1	2.2	2.3	-2.1	2.2	-2.1	2.2	2.3	2.1	2.2	2.3	2.1	-2.1	-2.2	1.9
Bone: trabecular spacing	3.8	4.9	8.9	-1.9	-2.5	-2.4	0.8	-2.3	1.9	-1.4	-1.9	-1.9	-2.4	-1.9	-2.7	2.7	2.5	-3.0
Total locomotion distance, hab. session 2	3.7	4.9	6.6	2.0	2.6	2.3	-1.4	2.4	-2.0	1.9	2.1	2.0	2.5	2.1	2.4	-2.4	-2.5	2.3
BMI without tail	3.6	7.6	8.9	-2.9	-2.7	-2.8	2.3	-2.9	2.9	-2.6	-2.7	-2.9	-2.8	-2.7	-2.8	2.8	2.8	-3.0
Condit. Reinf. inactive responses	3.3	3.9	5.3	1.7	2.2	2.3	-1.2	2.0	-1.7	1.6	1.8	1.7	2.2	1.8	2.3	-2.3	-2.2	2.3
Bone surface	3.3	5.9	12.5	1.9	2.8	2.6	-0.4	2.5	-1.9	1.3	2.0	1.9	2.7	2.0	3.1	-3.1	-2.8	3.5
Conditioned locomotion	3.1	3.7	4.3	-1.9	-2.1	-2.0	1.4	-2.0	1.9	-1.7	-1.9	-1.9	-2.0	-1.9	-2.0	2.0	2.0	-2.0
Bone volume	3.1	5.2	11.5	1.7	2.6	2.5	-0.3	2.4	-1.7	1.1	1.9	1.7	2.5	1.9	2.9	-2.9	-2.7	3.4
Breakpoint value in progressive ratio session	3.1	3.5	6.5	2.1	1.5	1.7	-2.6	1.8	-2.1	2.3	2.1	2.1	1.7	2.1	1.3	-1.2	-1.5	1.0
Intermittent access intake escalation 2	3.0	3.0	7.2	2.0	1.3	1.5	-2.7	1.5	-2.0	2.3	2.1	2.0	1.4	2.1	0.9	-0.9	-1.3	-0.4
Locomotion distance, session 1	3.0	3.9	5.9	1.4	2.4	2.3	-0.8	2.0	-1.4	1.4	1.8	1.4	2.3	1.8	2.4	-2.4	-2.3	2.3
Total zone transitions, hab. session 1	3.0	4.2	5.4	1.9	2.3	2.1	-1.3	2.2	-1.9	1.7	1.9	1.9	2.2	1.9	2.3	-2.3	-2.3	2.3
Time in familiar zone, hab. session 2	3.0	3.1	6.7	2.1	1.3	1.5	-2.6	1.6	-2.1	2.2	2.1	2.1	1.4	2.1	0.9	-0.9	-1.3	0.7
Pavlov. Cond. magazine entry latency	3.0	3.8	6.0	2.0	1.9	2.0	-2.5	1.8	-2.0	2.4	2.3	2.0	1.9	2.3	1.5	-1.4	-1.8	1.1
Bone: trabecular thickness	3.0	3.6	9.7	1.3	2.2	2.0	0.2	2.0	-1.3	0.6	1.4	1.3	2.1	1.4	2.5	-2.5	-2.3	3.1
Delay disc. indifference point, 2s delay	3.0	3.3	6.4	-2.1	-1.4	-1.6	2.5	-1.7	2.1	-2.3	-2.2	-2.1	-1.6	-2.2	-1.2	1.1	1.5	-0.5
Light reinforcement 2	2.9	3.9	4.9	2.1	1.8	2.0	-1.7	2.0	-2.1	1.8	1.9	2.1	1.9	1.9	2.0	-1.9	-1.9	2.2
Delay discounting water rate 18 sec	2.8	3.7	8.9	-1.3	-2.3	-2.1	0.1	-2.0	1.4	-0.9	-1.4	-1.3	-2.1	-1.4	-2.5	2.5	2.3	-3.0
Intermittent access day 15 total locomotion	2.8	2.9	4.4	1.8	1.5	1.7	-2.1	1.6	-1.8	2.0	2.0	1.8	1.6	2.0	1.3	-1.3	-1.5	1.4
Locomotion velocity, session 8	2.8	3.3	4.6	1.6	2.2	2.1	-1.2	1.9	-1.6	1.6	1.7	1.6	2.0	1.7	2.0	-2.0	-2.1	1.9
Reaction time trials AUC	2.7	3.9	6.5	-1.7	-2.2	-2.2	0.9	-2.0	1.7	-1.4	-1.7	-1.7	-2.1	-1.7	-2.4	2.4	2.2	-2.6
Mean time between licks in bursts	2.5	3.5	6.1	2.2	1.5	1.6	-2.5	1.8	-2.2	2.3	2.0	2.2	1.6	2.0	1.4	-1.3	-1.5	1.1
Reaction time number correct	2.5	3.6	5.8	-1.6	-2.0	-2.1	0.9	-2.0	1.7	-1.4	-1.7	-1.6	-2.0	-1.7	-2.3	2.3	2.1	-2.4
Reaction time trials correct on left	2.5	3.6	5.8	-1.6	-2.0	-2.1	0.9	-2.0	1.7	-1.4	-1.7	-1.6	-2.0	-1.7	-2.3	2.3	2.1	-2.4
Reaction time trials on left	2.4	3.4	5.4	-1.6	-2.0	-2.0	0.9	-1.9	1.6	-1.3	-1.7	-1.6	-2.0	-1.7	-2.2	2.2	2.0	-2.3
Reaction time trials completed	2.4	3.4	5.4	-1.6	-2.0	-2.0	0.9	-1.9	1.6	-1.3	-1.7	-1.6	-2.0	-1.7	-2.2	2.2	2.0	-2.3
Intermittent access intake escalation	2.4	2.3	6.1	1.7	1.1	1.3	-2.5	1.3	-1.7	2.1	1.9	1.7	1.2	1.9	0.8	-0.7	-1.1	-0.6
Active lever presses in extinction session 6	2.4	2.3	2.7	1.5	1.5	1.5	-1.6	1.6	-1.6	1.6	1.6	1.5	1.5	1.6	1.4	-1.4	-1.5	1.5
Delay discount hyperbolic model param	2.4	2.5	3.5	1.8	1.5	1.5	-1.9	1.6	-1.8	1.8	1.6	1.8	1.5	1.6	1.4	-1.4	-1.5	0.8
Locomotor testing distance	2.3	3.8	4.4	1.9	2.0	2.1	-1.7	2.0	-1.9	1.9	2.1	1.9	2.0	2.1	1.9	-1.9	-2.0	1.7
Time in novel zone, hab. session 2	2.3	2.4	5.1	-1.8	-1.1	-1.3	2.3	-1.4	1.8	-2.0	-1.8	-1.8	-1.2	-1.8	-1.0	0.9	1.1	-0.8
Time >=10cm from walls, locomotor time 2	2.3	2.5	3.1	-1.7	-1.5	-1.5	1.5	-1.6	1.7	-1.6	-1.5	-1.7	-1.5	-1.5	-1.6	1.5	1.5	-1.8
Bone: trabecular number	2.1	3.3	4.5	1.6	2.0	2.0	-1.0	1.9	-1.6	1.4	1.8	1.6	2.0	1.8	2.0	-2.0	-2.0	2.1
Delta time to tail flick, vehicle, before/after SA	2.1	2.1	8.0	-1.1	-1.5	-1.4	0.6	-1.5	1.3	-0.9	-0.9	-1.1	-1.5	-0.9	-1.6	1.6	1.5	-2.8
Delay disc. indifference point, 8s delay	2.1	2.2	2.7	-1.6	-1.5	-1.4	1.3	-1.6	1.6	-1.4	-1.2	-1.6	-1.5	-1.2	-1.6	1.6	1.5	-1.4
Tail length	2.0	5.9	10.7	2.5	2.2	2.3	-3.3	2.3	-2.6	3.1	3.0	2.5	2.3	3.0	1.5	-1.5	-2.1	1.0
Pavlov. Cond. latency score	2.0	2.5	3.8	1.3	1.9	1.9	-1.3	1.6	-1.3	1.6	1.7	1.3	1.8	1.7	1.6	-1.6	-1.8	1.3
Pavlov. Cond. lever-magazine prob. diff.	2.0	2.5	3.3	1.4	1.8	1.8	-1.5	1.5	-1.4	1.7	1.8	1.4	1.7	1.8	1.4	-1.4	-1.7	1.1
Run reversals in cocaine runway, males	2.0	1.9	2.2	1.5	1.4	1.4	-1.3	1.4	-1.5	1.4	1.5	1.5	1.4	1.5	1.3	-1.3	-1.4	1.0
Liver weight, left	1.9	3.1	3.7	-1.9	-1.7	-1.7	1.9	-1.8	1.9	-1.9	-1.9	-1.9	-1.7	-1.9	-1.6	1.6	1.7	-1.4
Short access day 10 total locomotion	1.9	2.1	4.2	1.7	1.2	1.3	-2.1	1.4	-1.7	1.9	1.7	1.7	1.3	1.7	1.0	-1.0	-1.2	0.6
Condit. Reinf. lever presses	1.9	2.5	4.9	1.1	1.9	1.8	-0.3	1.6	-1.1	0.9	1.2	1.1	1.8	1.2	2.1	-2.1	-1.9	2.2
Bone: trabecular tissue density	1.9	2.7	3.0	-1.7	-1.5	-1.7	1.5	-1.7	1.7	-1.6	-1.6	-1.7	-1.6	-1.6	-1.6	1.6	1.6	-1.6
Delta ambulatory time before/after self-admin	1.9	2.1	2.8	1.4	1.4	1.5	-1.6	1.4	-1.5	1.7	1.5	1.4	1.5	1.5	1.3	-1.3	-1.4	1.2
Delay discount exponential model param	1.9	2.0	2.5	1.6	1.3	1.3	-1.6	1.5	-1.6	1.6	1.4	1.6	1.4	1.4	1.3	-1.3	-1.3	0.7
Vertical activity count, locomotor time 2	1.9	2.0	2.5	-1.5	-1.5	-1.4	1.0	-1.6	1.5	-1.2	-1.2	-1.5	-1.5	-1.2	-1.6	1.6	1.6	-1.5
Conditioned reinforcement - actives	1.8	1.8	2.3	1.4	1.2	1.4	-1.5	1.2	-1.4	1.5	1.5	1.4	1.3	1.5	1.1	-1.1	-1.3	1.1
Cocaine induced anxiety	1.8	2.0	2.9	1.3	1.6	1.5	-0.8	1.5	-1.3	1.1	1.3	1.3	1.5	1.3	1.7	-1.7	-1.6	1.7
Post-drug Anxiety	1.8	2.0	3.4	1.3	1.5	1.5	-0.8	1.5	-1.3	1.1	1.3	1.3	1.5	1.3	1.6	-1.6	-1.5	1.9
Locomotion velocity, session 1	1.8	1.9	2.9	1.3	1.5	1.4	-0.7	1.5	-1.3	1.0	1.2	1.3	1.5	1.2	1.6	-1.6	-1.5	1.7
Bone: stiffness	1.8	2.9	4.1	-2.0	-1.4	-1.5	2.0	-1.7	2.0	-1.9	-1.8	-2.0	-1.5	-1.8	-1.4	1.4	1.5	-1.3
Total heroin consumption	1.8	2.1	2.5	1.6	1.3	1.4	-1.6	1.4	-1.6	1.6	1.6	1.6	1.4	1.6	1.3	-1.2	-1.4	1.4
Area under the delay curve	1.8	1.9	2.7	-1.6	-1.3	-1.3	1.6	-1.4	1.6	-1.6	-1.4	-1.6	-1.3	-1.4	-1.2	1.2	1.3	-0.7
Delay disc. indifference point, 0s delay	1.8	2.0	7.6	-1.7	-0.6	-0.8	2.8	-1.0	1.7	-2.1	-1.7	-1.7	-0.8	-1.7	-0.1	0.1	0.6	0.6
Weight adjusted by age	1.8	2.0	3.0	-1.2	-1.5	-1.4	0.8	-1.4	1.2	-1.1	-1.3	-1.2	-1.5	-1.3	-1.6	1.6	1.6	-1.7
Length with tail	1.7	6.4	8.1	2.6	2.5	2.6	-2.7	2.5	-2.7	2.8	2.8	2.6	2.5	2.8	2.2	-2.1	-2.4	2.0
Fecal boli incidents, locomotor time 1	1.7	1.8	2.5	-1.6	-1.2	-1.2	1.4	-1.4	1.6	-1.4	-1.2	-1.6	-1.3	-1.2	-1.3	1.3	1.3	-1.3
Bouts of movement, locomotor time 2	1.7	1.9	3.0	1.3	1.5	1.4	-0.8	1.5	-1.3	1.1	1.2	1.3	1.5	1.2	1.5	-1.5	-1.5	1.7
Total resting periods, locomotor time 2	1.7	1.8	2.9	1.3	1.5	1.4	-0.8	1.5	-1.3	1.1	1.2	1.3	1.5	1.2	1.5	-1.5	-1.5	1.7
Latency to leave start box in cocaine runway	1.7	1.9	3.3	1.4	1.3	1.3	-0.5	1.5	-1.4	0.9	1.0	1.4	1.4	1.0	1.8	-1.8	-1.5	1.8
Glucose	1.6	2.4	3.5	-1.5	-1.6	-1.6	1.7	-1.5	1.5	-1.7	-1.9	-1.5	-1.6	-1.9	-1.3	1.3	1.5	-1.0
Total zone transitions, hab. session 2	1.6	2.0	4.4	0.9	1.8	1.5	0.1	1.6	-0.9	0.6	0.9	0.9	1.7	0.9	2.0	-2.0	-1.8	2.1
Pavlov. Cond. response bias	1.6	2.0	2.8	1.3	1.5	1.5	-1.6	1.3	-1.3	1.7	1.6	1.3	1.4	1.6	1.1	-1.1	-1.4	0.8
Diff in mean of infusions in LGA sessions	1.6	1.7	2.5	1.4	1.2	1.4	-1.6	1.4	-1.5	1.6	1.3	1.4	1.3	1.3	1.0	-1.0	-1.2	1.0
Time to tail flick, vehicle, before self-admin	1.6	1.6	4.8	1.1	1.3	1.3	-0.7	1.3	-1.1	1.0	1.1	1.1	1.3	1.1	1.3	-1.3	-1.3	2.2
Delay discounting water rate 0 sec	1.5	2.4	6.0	-1.1	-1.8	-1.7	0.2	-1.6	1.2	-0.7	-1.2	-1.1	-1.7	-1.2	-1.9	1.9	1.8	-2.5
Social response proportion	1.5	1.6	2.0	1.3	1.4	1.2	-0.9	1.4	-1.3	1.1	1.2	1.3	1.3	1.2	1.4	-1.4	-1.4	1.3
Novel to familiar place preference ratio	1.5	1.5	4.7	-1.5	-0.7	-0.9	2.2	-1.0	1.5	-1.8	-1.6	-1.5	-0.8	-1.6	-0.3	0.3	0.7	-0.0
Pavlov. Cond. index score	1.5	2.0	2.8	1.1	1.7	1.7	-1.3	1.3	-1.1	1.5	1.6	1.1	1.5	1.6	1.3	-1.3	-1.5	1.0
Delta distance traveled before/after self-admin	1.5	1.6	2.4	1.2	1.2	1.3	-1.5	1.3	-1.4	1.5	1.4	1.2	1.3	1.4	1.1	-1.1	-1.2	1.1
Short access day 1 locomotion	1.4	1.5	1.9	1.2	1.3	1.4	-1.1	1.2	-1.2	1.2	1.4	1.2	1.3	1.4	1.2	-1.2	-1.3	1.1
Locomotion velocity, NPP test	1.4	2.0	3.6	1.1	1.7	1.5	-0.4	1.5	-1.1	0.9	1.1	1.1	1.6	1.1	1.9	-1.9	-1.7	1.9
Bone: maximum diameter	1.4	2.6	3.1	1.6	1.8	1.7	-1.2	1.7	-1.6	1.5	1.6	1.6	1.7	1.6	1.7	-1.7	-1.7	1.7
Reaction time num false alarms AUC	1.3	1.9	3.0	-1.2	-1.6	-1.3	0.5	-1.5	1.2	-0.9	-1.2	-1.2	-1.5	-1.2	-1.6	1.6	1.6	-1.7
Stereotopy head waving duration, day 7	1.3	1.5	2.4	1.1	1.4	1.4	-0.6	1.3	-1.1	0.9	1.0	1.1	1.4	1.0	1.5	-1.5	-1.4	1.5
Pavlov. Cond. lever contacts	1.3	1.5	2.6	0.8	1.6	1.5	-0.6	1.2	-0.8	1.0	1.2	0.8	1.5	1.2	1.4	-1.4	-1.5	1.3
Body weight	1.2	4.9	5.9	-2.4	-2.1	-2.2	2.3	-2.2	2.4	-2.4	-2.4	-2.4	-2.2	-2.4	-1.9	1.9	2.1	-1.8
Total zone transitions, NPP test	1.2	1.7	3.7	1.0	1.5	1.3	-0.1	1.4	-1.0	0.6	0.9	1.0	1.4	0.9	1.8	-1.8	-1.5	1.9
Bone: apparent density	1.2	2.0	5.6	0.9	1.6	1.6	0.3	1.4	-0.9	0.4	1.0	0.9	1.5	1.0	1.9	-1.9	-1.7	2.4
Delay disc. indifference point, 24s delay	1.2	1.2	1.4	-1.1	-1.1	-1.2	1.1	-1.1	1.1	-1.1	-1.2	-1.1	-1.1	-1.2	-1.1	1.1	1.1	-0.8
Food consumed during 24 hour testing period	1.1	1.3	1.8	-1.1	-1.0	-1.2	0.9	-1.1	1.1	-1.0	-1.0	-1.1	-1.1	-1.0	-1.3	1.3	1.1	-1.2
Times rat made contact with spout	1.1	1.2	2.1	-0.9	-1.1	-1.3	0.5	-1.1	0.9	-0.8	-0.9	-0.9	-1.2	-0.9	-1.5	1.5	1.2	-1.4
Total locomotion distance, NPP test	1.1	1.5	2.8	0.8	1.5	1.3	-0.2	1.3	-0.8	0.7	0.9	0.8	1.4	0.9	1.6	-1.7	-1.5	1.7
Pavlov. Cond. magazine entry number	1.1	1.4	2.0	-1.2	-1.2	-1.3	1.4	-1.1	1.2	-1.4	-1.4	-1.2	-1.2	-1.4	-0.9	0.9	1.1	-0.7
Right kidney weight	1.0	2.9	4.1	1.9	1.7	1.6	-2.0	1.8	-1.9	2.0	2.0	1.9	1.6	2.0	1.3	-1.2	-1.6	0.8
Reaction time num false alarms	1.0	1.3	2.0	-1.0	-1.4	-1.1	0.4	-1.3	1.0	-0.7	-1.0	-1.0	-1.3	-1.0	-1.3	1.3	1.3	-1.4
Intermittent access total locomotion	1.0	1.1	1.4	1.0	1.0	1.1	-1.1	0.9	-1.0	1.1	1.2	1.0	1.0	1.2	0.9	-0.9	-1.0	1.2
Intermittent access standard deviation	1.0	1.0	2.7	1.2	0.7	0.9	-1.7	0.8	-1.2	1.4	1.2	1.2	0.8	1.2	0.5	-0.5	-0.7	0.2
Time in novel zone, NPP test	1.0	1.0	3.1	-1.2	-0.6	-0.7	1.8	-0.8	1.2	-1.4	-1.2	-1.2	-0.7	-1.2	-0.3	0.3	0.6	-0.1
Bone: cortical porosity	1.0	1.1	1.6	1.0	1.1	1.2	-0.7	1.1	-1.0	0.9	1.0	1.0	1.1	1.0	1.2	-1.2	-1.1	1.2
Bone: maximum force	1.0	1.7	2.5	-1.6	-1.1	-1.1	1.5	-1.3	1.6	-1.4	-1.3	-1.6	-1.2	-1.3	-1.1	1.1	1.1	-1.0
Bone: tissue strength	1.0	1.0	2.0	-1.1	-0.8	-0.8	1.4	-0.9	1.1	-1.3	-1.1	-1.1	-0.8	-1.1	-0.6	0.6	0.8	-0.4
Time to tail flick, test, before self-admin	1.0	1.0	2.1	0.8	1.0	1.0	-0.4	1.0	-0.8	0.7	0.8	0.8	1.0	0.8	1.2	-1.2	-1.1	1.4
Vertical activity count, locomotor time 1	1.0	1.1	1.7	-0.9	-1.3	-1.2	0.9	-1.1	0.9	-1.1	-1.1	-0.9	-1.2	-1.1	-1.1	1.1	1.2	-0.6
Rest time, locomotor task time 2	1.0	1.2	1.6	1.1	1.2	1.2	-0.9	1.2	-1.1	1.1	1.1	1.1	1.2	1.1	1.0	-1.0	-1.2	0.8
Intraocular pressure	0.9	1.2	2.1	-0.7	-1.5	-1.3	0.2	-1.1	0.7	-0.7	-0.9	-0.7	-1.3	-0.9	-1.4	1.4	1.4	-1.3
Tibialis anterior weight	0.9	3.2	4.4	-2.1	-1.6	-1.6	1.9	-1.8	2.0	-1.9	-1.9	-2.1	-1.7	-1.9	-1.6	1.6	1.7	-1.5
Number of licking bursts	0.9	1.1	2.0	-0.8	-1.2	-1.2	0.3	-1.1	0.8	-0.6	-0.9	-0.8	-1.1	-0.9	-1.4	1.4	1.2	-1.4
Pavlov. Cond. intertrial magazine entries	0.9	1.1	1.6	-1.0	-1.1	-1.2	0.6	-1.1	1.0	-0.9	-1.0	-1.0	-1.2	-1.0	-1.2	1.2	1.2	-1.3
Short access day 1 total infusions	0.9	0.9	1.5	0.8	1.1	1.1	-0.5	0.9	-0.8	0.8	1.0	0.8	1.1	1.0	1.1	-1.1	-1.1	1.2
Locomotion distance, session 7	0.9	1.1	2.3	-1.0	-1.1	-1.1	0.4	-1.1	1.0	-0.7	-0.8	-1.0	-1.1	-0.8	-1.4	1.4	1.2	-1.5
Locomotion distance, session 8	0.9	1.3	1.9	0.9	1.3	1.4	-0.8	1.1	-0.9	1.0	1.2	0.9	1.3	1.2	1.2	-1.2	-1.3	1.1
Time in familiar zone, hab. session 1	0.9	0.9	2.2	1.1	0.7	0.7	-1.5	0.8	-1.1	1.2	1.3	1.1	0.7	1.3	0.3	-0.3	-0.6	0.2
Bone: cortical apparent density	0.9	1.2	1.8	-1.0	-1.0	-1.3	1.3	-1.0	1.0	-1.3	-1.2	-1.0	-1.1	-1.2	-0.9	0.9	1.0	-0.6
Distance moved, locomotor task time 2	0.9	1.1	1.2	-1.1	-1.1	-1.1	1.0	-1.1	1.1	-1.0	-1.1	-1.1	-1.1	-1.1	-0.9	0.9	1.1	-0.8
Food seeking constrained by brief footshock	0.9	1.1	1.7	0.9	1.3	1.3	-0.9	1.1	-0.9	1.1	1.3	0.9	1.2	1.3	0.9	-0.9	-1.2	0.7
Latency to leave start box in cocaine runway, F	0.9	1.0	3.5	0.6	1.0	0.8	0.5	1.0	-0.6	-0.0	0.3	0.6	1.0	0.3	1.6	-1.6	-1.1	1.9
Liver weight, right	0.8	1.3	2.3	-1.4	-0.8	-1.0	1.5	-1.1	1.4	-1.4	-1.2	-1.4	-1.0	-1.2	-0.9	0.8	0.9	-0.9
Delay discounting total patch changes 18 sec	0.8	1.0	1.4	1.1	0.9	1.0	-1.2	1.0	-1.1	1.2	1.1	1.1	1.0	1.1	0.9	-0.9	-0.9	0.6
Conditioned reinforcement - inactives	0.8	0.9	1.2	-1.1	-1.0	-0.9	0.7	-1.1	1.1	-0.8	-0.8	-1.1	-0.9	-0.8	-1.0	1.0	0.9	-0.8
Intermittent access day 15 total infusions	0.8	0.9	2.3	1.0	0.7	0.9	-1.5	0.8	-1.0	1.3	1.2	1.0	0.9	1.2	0.5	-0.5	-0.8	0.4
Short access total locomotion	0.8	0.8	1.0	0.9	0.9	1.0	-1.0	0.8	-0.9	1.0	1.0	0.9	0.9	1.0	0.8	-0.8	-0.9	0.9
Condit. Reinf. active-inactive response ratio	0.8	0.9	2.3	1.2	0.6	0.7	-1.5	0.8	-1.2	1.3	1.1	1.2	0.7	1.1	0.5	-0.5	-0.6	0.3
Bone: cortical porosity	0.8	0.9	1.9	0.7	1.0	1.1	-0.2	0.9	-0.7	0.5	0.7	0.7	1.0	0.7	1.3	-1.3	-1.1	1.4
Bone: maximum moment	0.8	1.4	2.0	-1.4	-1.0	-1.0	1.4	-1.2	1.4	-1.3	-1.2	-1.4	-1.1	-1.2	-1.0	0.9	1.0	-0.9
Time in open arm after self-admin	0.8	0.9	1.1	-1.0	-0.9	-1.0	1.0	-0.9	1.0	-1.1	-0.9	-1.0	-0.9	-0.9	-0.8	0.8	0.9	-0.5
Latency to leave start box in cocaine runway, M	0.8	0.7	2.6	1.0	0.4	0.6	-1.6	0.6	-1.0	1.3	0.9	1.0	0.5	0.9	0.2	-0.2	-0.4	-0.5
Delay discounting water rate 6 sec	0.7	1.0	2.5	-0.6	-1.2	-1.2	-0.3	-1.0	0.6	-0.2	-0.6	-0.6	-1.1	-0.6	-1.4	1.5	1.3	-1.6
Condit. Reinf. lever presses	0.7	1.0	2.7	1.2	0.6	0.7	-1.6	0.8	-1.2	1.4	1.1	1.2	0.7	1.1	0.5	-0.5	-0.6	0.3
Stereotopy head waving bouts, day 7	0.7	0.8	1.3	0.7	1.0	1.0	-0.3	0.9	-0.7	0.6	0.7	0.7	1.0	0.7	1.1	-1.1	-1.0	1.1
Novelty place preference	0.7	0.7	2.7	-1.0	-0.4	-0.5	1.7	-0.6	1.0	-1.3	-1.1	-1.0	-0.5	-1.1	-0.1	0.0	0.4	0.2
Pavlov. Cond. lever latency	0.7	0.9	1.7	-0.5	-1.3	-1.3	0.4	-0.9	0.5	-0.8	-1.0	-0.5	-1.2	-1.0	-1.1	1.1	1.2	-0.9
Bone: cortical thickness	0.7	0.8	1.6	-0.7	-1.1	-1.0	0.2	-1.0	0.7	-0.5	-0.7	-0.7	-1.0	-0.7	-1.1	1.1	1.1	-1.3
Bone: cortical tissue density	0.7	0.9	1.4	-0.8	-0.9	-1.2	1.1	-0.8	0.8	-1.2	-1.1	-0.8	-1.0	-1.1	-0.8	0.8	0.9	-0.6
Bone: final force	0.7	1.2	2.1	-1.4	-0.8	-0.9	1.4	-1.1	1.4	-1.3	-1.1	-1.4	-0.9	-1.1	-0.8	0.8	0.9	-0.7
Bone: post-yield work	0.7	1.0	1.7	-1.1	-0.9	-0.9	0.7	-1.1	1.1	-0.7	-0.9	-1.1	-1.0	-0.9	-1.1	1.1	1.0	-1.3
Distance traveled after self-admin	0.7	0.8	1.0	0.8	1.0	0.9	-0.8	0.9	-0.9	0.9	1.0	0.8	0.9	1.0	0.8	-0.8	-0.9	0.7
K content in liver	0.7	0.7	1.3	0.5	1.1	1.1	-0.3	1.0	-0.6	0.6	0.7	0.5	1.0	0.7	1.1	-1.1	-1.1	0.9
Std. dev. time between licks in bursts	0.6	0.8	1.0	1.0	0.8	0.8	-0.9	0.9	-1.0	1.0	0.8	1.0	0.9	0.8	0.8	-0.8	-0.8	0.7
Delay discounting total patch changes 12 sec	0.6	0.8	1.1	-0.9	-1.0	-0.9	0.7	-1.0	0.9	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	0.9	0.9	-1.1
Cocaine response before conditioning	0.6	0.8	1.0	0.9	0.9	0.9	-0.9	0.9	-0.9	1.0	0.9	0.9	0.9	0.9	0.8	-0.8	-0.8	0.6
Condit. Reinf. active-inactive response ratio	0.6	0.6	1.3	-0.4	-1.1	-1.0	0.2	-0.8	0.4	-0.6	-0.8	-0.4	-1.0	-0.8	-0.8	0.9	1.0	-0.8
Condit. Reinf. active responses	0.6	0.8	2.3	1.1	0.5	0.6	-1.5	0.8	-1.1	1.3	0.9	1.1	0.6	0.9	0.4	-0.4	-0.6	0.1
Condit. Reinf. inactive responses	0.6	0.7	1.6	0.9	0.8	0.7	-1.3	0.8	-0.9	1.2	1.0	0.9	0.7	1.0	0.4	-0.4	-0.7	0.1
Intermittent access terminal intake (last 3 days)	0.6	0.7	1.2	0.8	0.7	0.9	-1.1	0.6	-0.8	1.1	1.1	0.8	0.8	1.1	0.6	-0.6	-0.8	0.5
Degree of sensitization stereotypy	0.6	0.7	2.0	-1.0	-0.6	-0.6	1.4	-0.7	1.0	-1.2	-1.0	-1.0	-0.6	-1.0	-0.2	0.2	0.5	0.0
Bone: final moment	0.6	0.9	1.7	-1.2	-0.7	-0.8	1.3	-1.0	1.2	-1.2	-1.0	-1.2	-0.8	-1.0	-0.7	0.7	0.8	-0.6
Time to tail flick, test, after self-admin	0.6	0.6	0.8	0.9	0.8	0.8	-0.6	0.8	-0.8	0.7	0.8	0.9	0.8	0.8	0.8	-0.8	-0.8	0.1
Rest time, locomotor task time 1	0.6	0.7	1.2	0.7	1.0	1.0	-0.9	0.8	-0.7	1.0	1.1	0.7	0.9	1.1	0.6	-0.6	-0.9	-0.1
Seeking ratio, punishment vs. effort	0.6	0.8	1.2	0.8	1.0	1.0	-0.6	1.0	-0.9	0.8	0.9	0.8	1.0	0.9	0.8	-0.8	-1.0	1.1
Mg content in liver	0.6	0.7	1.3	0.5	1.0	0.9	-0.1	0.9	-0.6	0.5	0.5	0.5	0.9	0.5	1.1	-1.1	-1.0	1.0
Length without tail	0.5	1.0	2.2	0.8	1.1	1.1	-0.4	1.1	-0.9	0.7	0.8	0.8	1.1	0.8	1.3	-1.3	-1.1	1.5
Tibia length	0.5	1.5	2.6	1.3	1.1	1.1	-1.6	1.1	-1.3	1.5	1.4	1.3	1.1	1.4	0.8	-0.8	-1.1	0.5
Compulsive drug intake	0.5	0.5	1.5	-0.8	-0.4	-0.5	1.2	-0.5	0.8	-1.0	-0.9	-0.8	-0.5	-0.9	-0.2	0.2	0.4	0.1
Bone: connectivity density	0.5	0.8	2.7	0.4	1.0	0.9	0.6	0.8	-0.4	-0.0	0.5	0.4	0.9	0.5	1.2	-1.3	-1.1	1.6
Bone: cortical thickness	0.5	0.8	2.1	-1.1	-0.7	-0.8	1.5	-0.8	1.1	-1.3	-1.1	-1.1	-0.8	-1.1	-0.5	0.5	0.7	-0.2
Bone: endosteal perimeter	0.5	1.1	1.4	1.0	1.2	1.2	-0.9	1.1	-1.0	1.0	1.1	1.0	1.1	1.1	1.1	-1.1	-1.1	1.0
Delta time in open arm before/after self-admin	0.5	0.5	1.3	-0.8	-0.5	-0.5	1.1	-0.6	0.8	-1.0	-0.8	-0.8	-0.5	-0.8	-0.4	0.4	0.5	-0.0
Run reversals in cocaine runway, females	0.5	0.5	0.7	0.6	0.8	0.7	-0.8	0.7	-0.6	0.8	0.9	0.6	0.7	0.9	0.6	-0.6	-0.7	0.2
Se content in liver	0.5	0.6	1.0	0.6	0.9	1.0	-0.9	0.7	-0.6	1.0	1.0	0.6	0.8	1.0	0.6	-0.6	-0.8	0.3
Indifference point AUC	0.4	0.5	0.8	0.8	0.5	0.6	-0.9	0.7	-0.8	0.8	0.7	0.8	0.6	0.7	0.5	-0.5	-0.6	0.6
Indifference point function ln k	0.4	0.6	0.7	-0.8	-0.8	-0.8	0.6	-0.9	0.8	-0.7	-0.8	-0.8	-0.8	-0.8	-0.8	0.8	0.8	-0.9
Indifference point function log k	0.4	0.6	0.7	-0.8	-0.8	-0.8	0.6	-0.9	0.8	-0.7	-0.8	-0.8	-0.8	-0.8	-0.8	0.8	0.8	-0.9
Condit. Reinf. active minus inactive responses	0.4	0.5	1.9	0.9	0.2	0.3	-1.4	0.5	-0.9	1.0	0.7	0.9	0.3	0.7	0.1	-0.1	-0.2	-0.2
Pavlov. Cond. magazine entry number	0.4	0.5	1.0	-0.8	-0.6	-0.7	1.0	-0.7	0.8	-0.9	-0.8	-0.8	-0.7	-0.8	-0.5	0.5	0.6	-0.3
Pavlov. Cond. response bias	0.4	0.6	1.8	1.0	0.4	0.5	-1.4	0.6	-1.0	1.1	0.8	1.0	0.5	0.8	0.3	-0.2	-0.4	0.0
Pavlov. Cond. change in total contacts	0.4	0.4	0.7	0.4	0.8	0.8	-0.7	0.5	-0.4	0.8	0.8	0.4	0.7	0.8	0.4	-0.4	-0.7	0.2
Bone: periosteal perimeter	0.4	0.7	1.0	0.6	1.0	0.9	-0.3	0.8	-0.6	0.6	0.7	0.6	0.9	0.7	1.0	-1.0	-0.9	1.0
Ambulatory time after self-admin	0.4	0.5	0.6	0.6	0.8	0.7	-0.5	0.7	-0.7	0.6	0.8	0.6	0.7	0.8	0.6	-0.6	-0.7	0.6
Delay disc. indifference point, 4s delay	0.4	0.4	0.9	-0.8	-0.5	-0.5	1.0	-0.6	0.8	-0.8	-0.7	-0.8	-0.5	-0.7	-0.4	0.4	0.5	0.1
Sr content in liver	0.4	0.3	0.7	-0.4	-0.7	-0.6	-0.0	-0.6	0.4	-0.2	-0.4	-0.4	-0.7	-0.4	-0.8	0.8	0.7	-0.8
Retroperitoneal fat weight	0.3	0.9	1.4	-0.9	-0.9	-1.0	0.8	-1.0	1.0	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	0.9	0.9	-1.2
Water consumed over 24 hours	0.3	0.3	0.7	-0.7	-0.2	-0.4	0.9	-0.4	0.7	-0.7	-0.6	-0.7	-0.4	-0.6	-0.4	0.4	0.3	-0.3
Delay discounting time to switch 0 sec	0.3	0.4	1.3	-0.2	0.8	0.7	0.9	0.4	0.2	-0.4	0.1	-0.2	0.6	0.1	0.8	-0.8	-0.7	1.1
Reaction time omissions	0.3	0.4	0.8	0.9	0.5	0.5	-0.4	0.8	-0.9	0.4	0.4	0.9	0.6	0.4	0.7	-0.6	-0.6	0.9
Reaction time premature initiations	0.3	0.4	1.0	0.0	-0.9	-0.8	-0.6	-0.5	0.0	0.1	-0.3	0.0	-0.8	-0.3	-1.0	1.0	0.9	-1.0
Pavlov. Cond. latency score	0.3	0.3	0.7	0.7	0.4	0.5	-0.8	0.6	-0.7	0.7	0.6	0.7	0.5	0.6	0.4	-0.4	-0.4	0.3
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.8	0.8	0.5	0.5	-0.9	0.6	-0.8	0.8	0.7	0.8	0.5	0.7	0.4	-0.4	-0.5	0.3
Progressive ratio test 1 active lever presses	0.3	0.3	0.5	-0.5	-0.6	-0.6	0.1	-0.6	0.5	-0.3	-0.4	-0.5	-0.6	-0.4	-0.7	0.7	0.6	-0.3
Progressive ratio test 1 breakpoint	0.3	0.3	0.5	-0.6	-0.7	-0.6	0.2	-0.7	0.6	-0.4	-0.5	-0.6	-0.6	-0.5	-0.7	0.7	0.7	-0.4
Context. condit. distance diff. score	0.3	0.3	0.7	-0.7	-0.4	-0.3	0.3	-0.6	0.7	-0.3	-0.3	-0.7	-0.5	-0.3	-0.7	0.7	0.5	-0.9
Locomotion velocity, session 7	0.3	0.3	1.0	0.4	0.5	0.6	-1.0	0.3	-0.4	0.9	0.8	0.4	0.5	0.8	0.1	-0.0	-0.4	-0.3
Degree of sensitization distance	0.3	0.3	0.5	-0.7	-0.4	-0.5	0.6	-0.6	0.7	-0.5	-0.4	-0.7	-0.5	-0.4	-0.6	0.6	0.5	-0.6
Time in novel zone, hab. session 1	0.3	0.3	1.1	-0.6	-0.2	-0.2	1.1	-0.3	0.6	-0.8	-0.7	-0.6	-0.2	-0.7	0.1	-0.1	0.1	0.2
Extinction: sum of active levers before priming	0.3	0.3	1.2	0.6	0.3	0.5	-1.1	0.4	-0.6	0.9	0.7	0.6	0.4	0.7	0.1	-0.1	-0.3	0.1
Time in open arm before self-admin	0.3	0.3	0.8	0.6	0.4	0.3	-0.9	0.4	-0.6	0.8	0.7	0.6	0.4	0.7	0.3	-0.3	-0.3	0.4
Locomotion in novel chamber post-restriction	0.3	0.4	1.3	0.7	0.4	0.4	-1.1	0.4	-0.7	0.9	0.8	0.7	0.4	0.8	0.1	-0.1	-0.3	-0.5
Co content in liver	0.3	0.4	0.8	0.6	0.5	0.6	-0.9	0.6	-0.7	0.8	0.7	0.6	0.6	0.7	0.4	-0.4	-0.5	0.3
Zn content in liver	0.3	0.3	1.4	0.5	-0.3	-0.2	-1.2	0.1	-0.6	0.7	0.4	0.5	-0.2	0.4	-0.5	0.5	0.3	-0.7
Delay discounting total patch changes 6 sec	0.2	0.3	0.4	0.7	0.5	0.4	-0.4	0.6	-0.7	0.4	0.4	0.7	0.5	0.4	0.6	-0.6	-0.5	0.3
Reaction time premature initiation rate	0.2	0.3	1.0	0.8	0.2	0.2	-1.0	0.5	-0.8	0.8	0.5	0.8	0.3	0.5	0.2	-0.2	-0.2	0.3
Social time	0.2	0.2	0.8	-0.6	-0.3	-0.3	0.9	-0.4	0.6	-0.7	-0.6	-0.6	-0.3	-0.6	-0.0	0.0	0.3	0.1
Condit. Reinf. lever reinforcers received	0.2	0.3	1.5	0.8	0.1	0.2	-1.2	0.4	-0.8	0.9	0.5	0.8	0.2	0.5	0.0	0.0	-0.1	-0.3
Pavlov. Cond. lever latency	0.2	0.2	0.6	-0.6	-0.3	-0.4	0.8	-0.4	0.6	-0.6	-0.5	-0.6	-0.3	-0.5	-0.3	0.3	0.3	-0.2
Pavlov. Cond. magazine entry latency	0.2	0.3	0.6	0.6	0.5	0.5	-0.8	0.5	-0.6	0.7	0.6	0.6	0.5	0.6	0.3	-0.3	-0.4	0.2
Pavlov. Cond. index score	0.2	0.3	0.8	0.7	0.3	0.4	-0.9	0.5	-0.7	0.7	0.5	0.7	0.4	0.5	0.2	-0.2	-0.3	0.1
Intermitt. access day 1 inactive lever presses	0.2	0.2	0.7	-0.3	-0.5	-0.3	-0.2	-0.5	0.3	0.0	-0.1	-0.3	-0.4	-0.1	-0.6	0.7	0.5	-0.9
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.6	0.5	0.3	0.4	-0.8	0.3	-0.5	0.7	0.6	0.5	0.4	0.6	0.2	-0.2	-0.4	0.0
Intermitt. access escalation Index	0.2	0.1	0.7	0.1	0.4	0.2	0.4	0.4	-0.1	-0.1	-0.0	0.1	0.3	-0.0	0.5	-0.5	-0.3	0.9
Intermittent access day 1 locomotion	0.2	0.3	0.5	0.5	0.4	0.5	-0.7	0.4	-0.5	0.7	0.6	0.5	0.4	0.6	0.3	-0.3	-0.4	0.5
Short access day 1 total inactive lever presses	0.2	0.2	0.3	0.3	0.4	0.5	-0.4	0.3	-0.3	0.4	0.5	0.3	0.5	0.5	0.3	-0.3	-0.5	0.5
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.5	-0.1	-0.6	-0.5	-0.2	-0.4	0.1	-0.1	-0.2	-0.1	-0.5	-0.2	-0.7	0.7	0.6	-0.7
Bone: elastic work	0.2	0.3	0.6	-0.7	-0.5	-0.5	0.8	-0.6	0.7	-0.7	-0.5	-0.7	-0.5	-0.5	-0.4	0.4	0.5	-0.2
Distance traveled before self-admin	0.2	0.2	0.7	-0.4	-0.2	-0.3	0.8	-0.3	0.5	-0.7	-0.4	-0.4	-0.3	-0.4	-0.2	0.2	0.2	-0.2
Time in closed arm before self-admin	0.2	0.2	0.5	-0.1	0.5	0.5	0.7	0.4	0.1	-0.3	-0.2	-0.1	0.4	-0.2	0.7	-0.7	-0.5	0.7
Time to tail flick, vehicle, after self-admin	0.2	0.2	1.6	-0.1	-0.5	-0.4	-0.4	-0.5	0.2	0.1	0.0	-0.1	-0.4	0.0	-0.6	0.6	0.5	-1.3
Delta time to tail flick, test, before/after SA	0.2	0.2	1.8	0.1	-0.3	-0.1	-0.4	-0.2	-0.0	0.2	0.0	0.1	-0.2	0.0	-0.5	0.5	0.3	-1.3
Ambulatory time before self-admin	0.2	0.2	0.7	-0.5	-0.3	-0.4	0.8	-0.3	0.5	-0.7	-0.5	-0.5	-0.4	-0.5	-0.2	0.2	0.3	-0.1
Total resting periods, locomotor time 1	0.2	0.2	0.5	0.4	0.4	0.4	-0.7	0.3	-0.4	0.6	0.6	0.4	0.4	0.6	0.1	-0.1	-0.3	-0.2
Distance moved, locomotor task time 1	0.2	0.2	1.1	-0.3	-0.1	-0.1	1.0	-0.1	0.3	-0.8	-0.5	-0.3	-0.1	-0.5	0.3	-0.3	-0.0	0.6
Cd content in liver	0.2	0.2	0.4	-0.4	-0.4	-0.4	0.6	-0.4	0.4	-0.6	-0.6	-0.4	-0.4	-0.6	-0.1	0.1	0.3	0.1
Cu content in liver	0.2	0.2	0.8	0.1	0.7	0.6	0.2	0.4	-0.1	0.1	0.3	0.1	0.6	0.3	0.7	-0.7	-0.6	0.9
Na content in liver	0.2	0.2	0.4	-0.4	0.5	0.5	0.6	0.1	0.4	-0.2	-0.1	-0.4	0.3	-0.1	0.5	-0.5	-0.4	0.5
Rb content in liver	0.2	0.2	0.7	-0.0	0.5	0.4	0.5	0.4	-0.0	-0.2	0.0	-0.0	0.4	0.0	0.7	-0.7	-0.5	0.8
Epididymis fat weight	0.1	0.3	0.7	0.6	0.5	0.6	-0.8	0.5	-0.6	0.7	0.7	0.6	0.5	0.7	0.3	-0.3	-0.5	-0.0
Left kidney weight	0.1	0.3	0.5	0.5	0.7	0.4	-0.2	0.7	-0.6	0.4	0.5	0.5	0.6	0.5	0.6	-0.6	-0.6	0.5
Parametrial fat weight	0.1	0.2	0.8	0.5	0.3	0.3	-0.9	0.4	-0.5	0.7	0.6	0.5	0.3	0.6	0.2	-0.2	-0.3	-0.1
Indifference point 0 sec	0.1	0.1	0.3	-0.3	-0.2	-0.2	0.6	-0.2	0.3	-0.4	-0.4	-0.3	-0.2	-0.4	0.0	-0.0	0.1	-0.2
Delay discounting total patch changes 0 sec	0.1	0.1	0.2	-0.4	-0.3	-0.3	0.4	-0.3	0.4	-0.4	-0.4	-0.4	-0.3	-0.4	-0.2	0.1	0.2	-0.4
Delay discounting total patch changes 24 sec	0.1	0.1	0.4	0.4	0.3	0.3	-0.2	0.4	-0.4	0.2	0.2	0.4	0.3	0.2	0.4	-0.4	-0.3	0.7
Locomotor testing rearing	0.1	0.2	0.3	-0.3	-0.5	-0.5	-0.0	-0.5	0.3	-0.1	-0.3	-0.3	-0.5	-0.3	-0.6	0.6	0.5	-0.6
Reaction time mean minus median	0.1	0.2	0.7	0.6	0.2	0.3	-0.8	0.4	-0.6	0.7	0.4	0.6	0.2	0.4	0.1	-0.1	-0.2	-0.2
Reaction time mean minus median AUC	0.1	0.2	0.3	0.3	0.5	0.4	-0.1	0.5	-0.3	0.2	0.3	0.3	0.5	0.3	0.5	-0.5	-0.5	0.5
Median of all reaction times	0.1	0.1	0.5	-0.3	-0.2	-0.3	0.7	-0.2	0.3	-0.6	-0.5	-0.3	-0.3	-0.5	-0.0	0.0	0.2	0.3
Saline control response	0.1	0.1	0.2	-0.3	-0.4	-0.4	0.3	-0.3	0.3	-0.3	-0.5	-0.3	-0.4	-0.5	-0.2	0.2	0.4	-0.3
Pavlov. Cond. change in total contacts	0.1	0.2	0.5	0.6	0.1	0.2	-0.7	0.4	-0.6	0.5	0.3	0.6	0.2	0.3	0.2	-0.2	-0.2	0.2
Pavlov. Cond. lever contacts	0.1	0.1	0.6	0.5	0.0	0.1	-0.8	0.2	-0.5	0.6	0.3	0.5	0.1	0.3	-0.0	0.0	-0.0	-0.2
Intermittent access day 1 total infusions	0.1	0.1	0.7	-0.2	-0.0	0.0	0.2	-0.1	0.2	-0.1	-0.0	-0.2	-0.0	-0.0	-0.0	0.0	0.0	0.8
Intermittent access total infusions	0.1	0.1	0.2	0.2	0.2	0.3	-0.5	0.1	-0.2	0.4	0.4	0.2	0.2	0.4	0.1	-0.1	-0.2	0.4
Baseline Anxiety	0.1	0.1	0.4	-0.0	-0.4	-0.3	-0.4	-0.3	0.0	0.2	-0.0	-0.0	-0.3	-0.0	-0.5	0.5	0.4	-0.6
Lifetime Intake	0.1	0.1	0.2	0.1	0.2	0.3	-0.3	0.1	-0.1	0.3	0.3	0.1	0.2	0.3	0.1	-0.1	-0.2	0.4
Incentive Sensitization - Responses	0.1	0.1	0.9	-0.2	-0.3	-0.2	-0.2	-0.3	0.2	0.0	-0.0	-0.2	-0.3	-0.0	-0.4	0.4	0.3	-0.9
Incentive Sensitization - Breakpoint	0.1	0.1	0.6	-0.1	-0.2	-0.1	-0.3	-0.2	0.1	0.1	0.1	-0.1	-0.1	0.1	-0.3	0.3	0.1	-0.8
Progressive ratio test 2 active lever presses	0.1	0.1	0.3	-0.1	-0.3	-0.2	-0.3	-0.3	0.1	0.1	0.0	-0.1	-0.2	0.0	-0.4	0.4	0.3	-0.5
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.3	0.2	0.4	0.5	-0.2	0.3	-0.2	0.3	0.5	0.2	0.5	0.5	0.4	-0.4	-0.5	0.5
One hour access (0.3 mA shock)	0.1	0.2	0.3	-0.5	-0.5	-0.4	0.4	-0.5	0.5	-0.4	-0.4	-0.5	-0.4	-0.4	-0.3	0.3	0.4	0.1
One hour access (shock baseline)	0.1	0.1	0.2	-0.2	-0.5	-0.3	-0.4	-0.4	0.2	0.1	-0.1	-0.2	-0.4	-0.1	-0.5	0.5	0.4	-0.3
Number of responses in last shaping day	0.1	0.1	0.2	0.2	0.3	0.4	-0.4	0.2	-0.2	0.4	0.4	0.2	0.3	0.4	0.2	-0.2	-0.3	0.3
Locomotion distance, session 3	0.1	0.1	0.2	-0.2	-0.3	-0.3	-0.1	-0.3	0.2	-0.0	-0.2	-0.2	-0.3	-0.2	-0.3	0.4	0.3	-0.5
Bone: cortical area	0.1	0.2	0.8	-0.5	-0.0	-0.2	0.9	-0.2	0.5	-0.6	-0.4	-0.5	-0.2	-0.4	0.0	-0.0	0.1	0.3
Bone: elastic displacement	0.1	0.1	0.3	0.3	0.2	0.3	-0.2	0.3	-0.3	0.2	0.3	0.3	0.3	0.3	0.4	-0.4	-0.3	0.5
Bone: endosteal estimation	0.1	0.2	0.4	-0.6	-0.3	-0.4	0.5	-0.5	0.6	-0.4	-0.4	-0.6	-0.4	-0.4	-0.4	0.4	0.4	-0.4
Bone: marrow area	0.1	0.2	0.4	-0.6	-0.3	-0.4	0.5	-0.5	0.6	-0.4	-0.4	-0.6	-0.4	-0.4	-0.4	0.4	0.4	-0.5
Delay disc. indifference point, 16s delay	0.1	0.1	0.1	-0.3	-0.4	-0.3	0.4	-0.3	0.3	-0.4	-0.3	-0.3	-0.3	-0.3	-0.4	0.4	0.3	-0.1
Change in fecal boli incidents, locomotor task	0.1	0.1	0.2	0.4	0.4	0.4	-0.3	0.4	-0.4	0.4	0.3	0.4	0.4	0.3	0.4	-0.4	-0.4	0.4
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.9	-0.4	0.2	0.1	0.9	-0.0	0.4	-0.6	-0.3	-0.4	0.1	-0.3	0.2	-0.3	-0.2	-0.1
Bouts of movement, locomotor time 1	0.1	0.1	0.4	0.2	0.2	0.2	-0.6	0.1	-0.2	0.5	0.4	0.2	0.2	0.4	-0.1	0.1	-0.1	-0.4
Locomotion in novel chamber	0.1	0.1	0.8	0.3	-0.2	-0.3	-0.3	-0.1	-0.1	0.1	-0.0	0.3	-0.3	-0.0	-0.4	0.4	0.3	-0.9
Progressive ratio	0.1	0.2	0.7	-0.4	-0.3	-0.3	0.2	-0.5	0.5	-0.3	-0.2	-0.4	-0.3	-0.2	-0.4	0.4	0.3	-0.8
Heart weight	0.0	0.0	0.1	0.2	-0.3	-0.2	-0.4	-0.0	-0.3	0.2	0.0	0.2	-0.1	0.0	-0.2	0.2	0.2	-0.3
Mean num. licks in bursts	0.0	0.0	0.0	0.1	0.2	0.2	0.1	0.2	-0.1	-0.0	0.1	0.1	0.1	0.1	0.2	-0.2	-0.2	0.2
Reaction time mean	0.0	0.0	0.1	0.1	-0.0	-0.1	0.2	0.1	-0.0	-0.2	-0.2	0.1	-0.0	-0.2	0.1	-0.1	0.0	0.3
Reaction time mean AUC	0.0	0.0	0.1	-0.0	-0.1	-0.2	0.4	0.1	0.0	-0.3	-0.3	-0.0	-0.1	-0.3	0.1	-0.1	0.1	0.3
Reaction time false alarm rate	0.0	0.1	0.1	-0.3	-0.3	-0.1	0.2	-0.4	0.3	-0.2	-0.3	-0.3	-0.3	-0.3	-0.2	0.2	0.3	-0.2
Std. dev. reaction times	0.0	0.0	0.1	0.4	0.0	0.0	-0.3	0.3	-0.4	0.3	0.1	0.4	0.1	0.1	0.1	-0.1	-0.1	-0.0
Progressive ratio test 1 inactive lever presses	0.0	0.0	0.1	0.2	0.2	0.2	-0.3	0.1	-0.2	0.3	0.3	0.2	0.2	0.3	0.1	-0.1	-0.2	0.3
Progressive ratio test 2 breakpoint	0.0	0.0	0.2	0.2	0.1	0.2	-0.4	0.1	-0.2	0.3	0.3	0.2	0.2	0.3	0.0	-0.0	-0.1	-0.1
Total sessions with >9 infusions	0.0	0.0	0.2	-0.0	0.2	0.2	0.1	0.1	0.0	-0.0	0.1	-0.0	0.2	0.1	0.2	-0.2	-0.2	0.5
Short access day 10 total inactive lever presses	0.0	0.0	0.1	-0.2	-0.2	-0.1	0.0	-0.2	0.2	-0.1	-0.1	-0.2	-0.2	-0.1	-0.3	0.3	0.2	-0.4
Short access day 10 total infusions	0.0	0.0	0.1	-0.2	-0.3	-0.2	-0.3	-0.3	0.2	0.1	-0.0	-0.2	-0.2	-0.0	-0.4	0.4	0.3	0.0
Short access total infusions	0.0	0.0	0.1	0.0	0.2	0.2	-0.0	0.1	-0.0	0.1	0.2	0.0	0.2	0.2	0.2	-0.2	-0.2	0.4
Bone: minimum diameter	0.0	0.1	0.2	0.1	0.4	0.3	-0.1	0.2	-0.1	0.2	0.2	0.1	0.3	0.2	0.3	-0.3	-0.3	0.2
Bone: periosteal estimation	0.0	0.1	0.4	-0.4	0.1	-0.0	0.7	-0.2	0.4	-0.4	-0.2	-0.4	-0.1	-0.2	0.1	-0.1	0.0	0.2
Time in closed arm after self-admin	0.0	0.0	0.5	-0.0	-0.1	-0.0	-0.1	-0.0	-0.0	0.0	-0.1	-0.0	-0.1	-0.1	-0.1	0.1	0.1	-0.7
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.2	0.0	0.2	0.2	0.0	0.1	-0.1	0.0	0.1	0.0	0.2	0.1	0.2	-0.2	-0.2	0.5
Fe content in liver	0.0	0.1	0.3	-0.1	-0.0	0.2	-0.4	-0.1	0.0	0.3	0.2	-0.1	-0.0	0.2	-0.2	0.2	0.1	-0.6

For each tested trait, stats based on TWAS chi² (squared Z-score) for the above models are shown. Avg chi² ratio is the mean chi² across all models for this gene, divided by the mean chi² across all models for all genes. Avg chi² is the mean chi² across all models for this gene. Max chi² is the highest chi² across all models for this gene.

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.