Hub : Genes

Taco1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000008405 0.1 0.05 1.3e-08 0.07 0.05 0.05 0.05 7.1e-08 2.5e-06 7.3e-06 3.1e-06
2 Adipose mRNA stability ENSRNOG00000008405 0.12 0.05 8.6e-12 0.07 0.08 0.09 0.09 2.3e-08 1.7e-09 9.2e-10 1.1e-09
3 BLA gene expression ENSRNOG00000008405 0.06 0.03 6.1e-04 0.05 0.05 0.04 0.05 1.5e-03 7.5e-04 2.5e-03 1.1e-03
4 BLA mRNA stability ENSRNOG00000008405 0.15 0.06 1.4e-09 0.1 0.14 0.09 0.12 4.5e-06 1.1e-07 1.2e-05 9.4e-07
5 Brain mRNA stability ENSRNOG00000008405 0.16 0.06 0.0e+00 0.22 0.22 0.22 0.23 3.4e-20 1.6e-20 1.6e-20 6.3e-21
6 LHb mRNA stability ENSRNOG00000008405 0.24 0.1 8.3e-05 0.18 0.14 0.1 0.16 4.2e-05 4.2e-04 2.3e-03 1.5e-04
7 Liver gene expression ENSRNOG00000008405 0.09 0.04 1.3e-10 0.07 0.08 0.08 0.07 9.6e-09 1.4e-09 3.4e-09 1.3e-08
8 Liver mRNA stability ENSRNOG00000008405 0.1 0.04 4.2e-15 0.11 0.12 0.12 0.12 9.4e-12 5.3e-13 2.6e-13 8.3e-13
9 NAcc mRNA stability ENSRNOG00000008405 0.17 0.09 2.1e-09 0.14 0.1 0.11 0.13 9.4e-11 6.4e-08 1.5e-08 4.7e-10
10 PL mRNA stability ENSRNOG00000008405 0.15 0.06 9.6e-11 0.13 0.14 0.14 0.14 4.9e-10 1.2e-10 5.5e-11 1.5e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.10.41.00.80.6-0.70.50.71.00.60.70.20.6
BMI without tail0.71.44.4-0.9-1.0-2.1-1.0-1.0-0.6-1.3-0.5-1.4-1.2
Body weight1.45.910.5-1.9-2.5-3.2-2.5-2.2-2.1-2.0-2.5-2.8-2.2
Epididymis fat weight0.61.43.4-0.9-1.0-1.8-1.0-1.2-0.8-1.4-0.8-1.5-1.0
Glucose0.91.42.81.11.21.11.11.20.91.70.61.01.5
Heart weight0.10.10.40.30.3-0.10.20.20.20.6-0.3-0.10.6
Left kidney weight0.30.91.51.01.20.91.10.90.91.20.60.60.7
Right kidney weight0.10.10.30.50.40.50.50.40.20.60.00.0-0.2
Tail length2.47.18.2-2.5-2.8-2.7-2.6-2.7-2.6-2.8-2.4-2.9-2.7
Length with tail2.38.510.6-2.6-3.1-2.7-2.9-2.8-3.1-2.5-3.3-3.2-2.8
Length without tail0.61.22.4-0.9-1.2-0.7-1.1-1.0-1.5-0.7-1.6-1.3-0.9
Liver weight, left0.81.22.6-1.1-1.2-0.7-1.1-1.0-1.2-1.1-1.6-1.1-0.7
Liver weight, right0.20.30.90.60.80.81.00.60.60.4-0.10.10.2
Parametrial fat weight1.73.25.3-1.6-1.5-1.6-1.4-1.8-1.9-1.9-1.7-2.3-2.1
Retroperitoneal fat weight1.24.15.4-1.6-2.3-2.3-2.0-1.8-1.7-2.3-1.9-2.0-2.2
Intraocular pressure0.50.62.1-0.5-0.5-1.5-0.6-0.7-0.5-0.7-0.6-1.1-0.8
Extensor digitorum longus weight2.510.114.73.83.11.63.03.73.62.83.62.83.3
Soleus weight0.20.50.7-0.7-0.6-0.8-0.7-0.7-0.8-0.2-0.6-0.8-0.5
Tibialis anterior weight0.10.20.80.50.1-0.9-0.10.40.4-0.20.6-0.20.3
Tibia length0.00.10.6-0.1-0.10.10.0-0.3-0.20.1-0.6-0.4-0.7
Number of licking bursts0.00.10.3-0.0-0.10.1-0.1-0.1-0.30.3-0.5-0.10.2
Food consumed during 24 hour testing period2.12.54.2-1.3-1.8-2.1-1.7-1.4-1.4-1.6-1.5-1.7-1.2
Times rat made contact with spout0.91.01.2-1.0-1.1-1.0-1.1-1.1-0.9-0.9-0.9-0.8-1.0
Mean time between licks in bursts0.00.00.20.10.2-0.4-0.00.00.20.3-0.1-0.1-0.0
Mean num. licks in bursts0.20.30.7-0.4-0.4-0.7-0.4-0.5-0.1-0.80.0-0.4-0.7
Std. dev. time between licks in bursts0.00.00.10.30.2-0.10.20.20.2-0.00.3-0.00.0
Water consumed over 24 hours0.10.10.3-0.2-0.3-0.3-0.2-0.3-0.2-0.5-0.1-0.4-0.5
Indifference point 0 sec3.65.88.2-2.3-2.5-2.5-2.4-2.4-2.0-2.9-2.6-2.3-2.0
Indifference point AUC0.60.71.4-0.6-0.8-1.0-0.9-0.6-0.7-0.8-1.2-0.8-0.7
Indifference point function ln k0.00.00.1-0.10.20.30.2-0.2-0.3-0.1-0.1-0.3-0.1
Indifference point function log k0.00.00.1-0.10.20.30.2-0.2-0.3-0.1-0.1-0.3-0.1
Delay discounting total patch changes 0 sec4.16.68.5-2.5-2.6-2.7-2.5-2.5-2.2-2.9-2.8-2.5-2.2
Delay discounting total patch changes 12 sec3.24.37.1-1.9-2.4-2.1-2.2-1.9-1.6-2.4-2.7-1.6-1.5
Delay discounting total patch changes 18 sec2.22.93.8-1.7-1.9-1.9-1.9-1.6-1.5-1.7-2.0-1.5-1.4
Delay discounting total patch changes 24 sec3.74.76.0-2.1-2.1-2.1-2.1-2.2-1.9-2.4-2.5-2.1-2.0
Delay discounting total patch changes 6 sec2.23.44.2-1.8-1.9-1.9-1.9-1.9-1.7-1.9-2.0-1.8-1.7
Delay discounting time to switch 0 sec0.10.20.90.20.20.40.20.4-0.00.40.90.30.2
Delay discounting water rate 0 sec1.52.43.3-1.3-1.4-1.8-1.4-1.6-1.2-1.7-1.6-1.7-1.7
Delay discounting water rate 12 sec0.40.61.20.81.10.81.10.60.81.10.60.50.4
Delay discounting water rate 18 sec0.10.10.4-0.4-0.10.1-0.0-0.4-0.3-0.3-0.6-0.4-0.5
Delay discounting water rate 24 sec0.00.00.20.1-0.00.20.00.0-0.10.3-0.5-0.00.1
Delay discounting water rate 6 sec0.10.20.7-0.50.0-0.20.0-0.5-0.3-0.5-0.1-0.6-0.8
Locomotor activity0.40.61.1-0.8-1.1-0.7-1.0-0.9-0.7-0.8-0.3-0.4-0.6
Locomotor testing distance1.32.23.2-1.7-1.7-1.6-1.8-1.8-1.2-1.6-0.7-0.9-1.3
Locomotor testing rearing1.01.52.8-1.4-1.6-1.3-1.7-1.5-0.9-1.3-0.2-0.3-1.1
Light reinforcement 10.20.41.4-0.4-0.2-0.5-0.2-0.3-0.4-1.2-0.5-1.0-0.5
Light reinforcement 20.71.02.6-0.9-0.4-0.8-0.5-1.0-0.8-1.6-0.9-1.4-1.1
Reaction time number correct0.60.81.20.91.10.91.10.80.91.10.20.61.0
Reaction time mean minus median0.20.20.50.70.50.50.60.60.40.40.50.40.3
Reaction time mean minus median AUC1.11.41.81.31.31.31.31.31.11.10.91.00.9
Reaction time num false alarms3.54.85.8-2.2-2.4-2.1-2.4-2.2-2.4-1.7-2.4-2.2-1.8
Reaction time num false alarms AUC4.05.66.8-2.4-2.5-2.3-2.5-2.4-2.5-2.0-2.6-2.4-2.0
Reaction time trials correct on left0.60.81.20.91.10.91.10.80.91.10.20.61.0
Reaction time trials on left0.50.71.10.91.00.81.00.80.91.10.20.60.9
Reaction time mean0.50.71.50.90.81.21.00.90.70.70.70.90.6
Reaction time mean AUC0.81.02.01.01.01.41.11.10.70.80.91.00.8
Median of all reaction times0.50.71.60.80.81.30.90.90.60.70.70.90.6
Reaction time omissions0.10.20.5-0.4-0.1-0.2-0.0-0.4-0.5-0.6-0.3-0.7-0.7
Reaction time false alarm rate4.15.87.1-2.5-2.7-2.3-2.6-2.3-2.6-2.2-2.3-2.3-2.1
Reaction time premature initiation rate1.01.32.4-1.3-0.8-1.4-1.0-1.3-0.7-1.3-0.6-1.0-1.5
Reaction time premature initiations0.30.40.8-0.7-0.2-0.8-0.4-0.8-0.1-0.7-0.5-0.6-0.9
Std. dev. reaction times0.20.30.60.70.60.70.70.70.40.40.50.40.3
Reaction time trials completed0.50.71.10.91.00.81.00.80.91.10.20.60.9
Reaction time trials AUC0.60.91.20.91.10.91.10.81.01.10.30.71.0
Social response proportion0.30.30.90.70.60.20.50.60.61.00.00.50.6
Social responses0.00.00.1-0.1-0.3-0.3-0.3-0.1-0.10.1-0.4-0.0-0.1
Social time0.20.20.5-0.6-0.3-0.7-0.5-0.6-0.30.1-0.6-0.2-0.2
Conditioned locomotion0.30.30.7-0.4-0.6-0.6-0.5-0.5-0.4-0.8-0.7-0.4-0.3
Cocaine response after cond. corrected0.10.20.70.30.40.30.40.30.10.9-0.10.10.4
Cocaine response after cond. not corrected0.10.10.8-0.10.20.50.20.0-0.30.9-0.20.00.0
Cocaine response before conditioning0.10.10.3-0.5-0.20.4-0.2-0.4-0.5-0.1-0.1-0.1-0.6
Saline control response0.70.91.7-1.0-1.0-1.3-1.2-1.0-0.6-1.2-0.7-0.6-0.5
Condit. Reinf. active minus inactive responses8.310.313.9-3.5-3.2-2.6-3.2-3.6-3.3-2.9-3.7-2.9-2.9
Condit. Reinf. active-inactive response ratio6.46.78.4-2.9-2.6-2.1-2.6-2.9-2.8-2.4-2.7-2.5-2.4
Condit. Reinf. active responses7.710.814.0-3.5-3.2-2.9-3.3-3.6-3.2-3.2-3.7-3.0-2.9
Condit. Reinf. inactive responses1.41.72.7-1.2-1.3-1.4-1.3-1.3-1.1-1.6-1.6-1.2-1.0
Condit. Reinf. lever presses2.33.23.9-2.0-1.9-1.6-1.9-1.9-1.9-1.8-1.8-1.6-1.8
Condit. Reinf. lever reinforcers received6.99.712.5-3.4-3.0-2.8-3.1-3.4-3.1-3.1-3.5-2.9-2.8
Pavlov. Cond. lever latency0.40.51.00.90.70.50.80.80.80.51.00.60.4
Pavlov. Cond. magazine entry latency2.73.15.01.71.71.91.61.81.62.21.21.91.9
Pavlov. Cond. change in total contacts0.20.30.7-0.6-0.7-0.3-0.7-0.5-0.4-0.3-0.8-0.1-0.0
Pavlov. Cond. index score0.00.10.2-0.1-0.00.3-0.10.0-0.10.5-0.30.30.2
Pavlov. Cond. latency score0.10.10.3-0.20.00.3-0.10.0-0.10.6-0.20.30.2
Pavlov. Cond. lever contacts0.30.40.5-0.7-0.6-0.5-0.6-0.6-0.6-0.6-0.7-0.5-0.4
Pavlov. Cond. magazine entry number3.23.95.8-1.8-1.9-2.2-1.8-2.0-1.8-2.4-1.4-2.2-1.9
Pavlov. Cond. intertrial magazine entries14.318.422.1-4.0-4.2-4.7-4.2-4.3-4.2-4.6-3.9-4.6-4.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.00.10.40.00.10.00.6-0.30.40.4
Pavlov. Cond. response bias0.00.00.1-0.2-0.10.1-0.1-0.0-0.00.1-0.40.10.1
Conditioned reinforcement - actives0.50.40.9-0.7-0.7-0.9-0.8-0.6-0.5-0.7-0.3-0.6-0.6
Conditioned reinforcement - inactives1.21.31.8-1.1-1.2-1.3-1.2-1.1-1.2-1.1-1.0-1.3-1.1
Conditioned locomotion2.83.44.3-1.9-1.8-2.1-1.9-1.9-1.7-1.8-1.4-1.9-1.9
Intermittent access intake day 1-15 change0.20.20.4-0.4-0.6-0.6-0.7-0.3-0.7-0.1-0.3-0.30.0
Intermittent access intake escalation0.00.00.1-0.0-0.2-0.2-0.30.0-0.30.10.1-0.00.3
Intermittent access intake escalation 20.50.50.8-0.7-0.9-0.8-0.9-0.7-0.8-0.6-0.5-0.6-0.5
Intermitt. access day 1 inactive lever presses6.77.29.1-2.7-2.7-2.4-2.7-2.7-2.9-2.5-3.0-2.7-2.5
Intermitt. access day 15 inactive lever presses4.44.86.2-2.2-1.9-2.2-1.9-2.3-2.3-2.5-1.5-2.5-2.4
Intermitt. access escalation Index4.03.55.71.81.72.01.71.91.72.41.12.02.2
Intermittent access day 1 total infusions0.80.91.6-0.9-0.9-1.1-0.9-0.9-1.0-0.8-0.9-1.3-0.8
Intermittent access day 15 total infusions0.30.30.9-0.4-0.6-0.9-0.7-0.4-0.6-0.4-0.2-0.8-0.2
Intermittent access terminal intake (last 3 days)2.12.33.4-1.5-1.6-1.8-1.7-1.5-1.5-1.5-1.2-1.7-1.2
Intermittent access total infusions2.52.83.7-1.6-1.8-1.9-1.8-1.6-1.7-1.7-1.3-1.9-1.4
Intermittent access day 1 locomotion4.24.35.7-2.1-2.0-2.4-2.1-2.2-2.0-2.0-1.1-2.3-2.3
Intermittent access day 15 total locomotion4.95.36.5-2.2-2.5-2.6-2.5-2.3-2.2-2.2-1.7-2.3-2.3
Intermittent access total locomotion8.39.311.4-3.0-3.2-3.4-3.1-3.1-2.9-3.2-2.1-3.2-3.3
Intermittent access standard deviation1.81.92.5-1.3-1.4-1.6-1.4-1.3-1.5-1.5-0.4-1.5-1.4
Cocaine induced anxiety0.10.10.6-0.30.2-0.10.1-0.3-0.0-0.10.7-0.2-0.8
Post-drug Anxiety0.10.10.5-0.10.5-0.00.3-0.10.10.20.7-0.1-0.7
Baseline Anxiety0.80.81.11.01.10.91.01.00.91.00.60.80.7
Lifetime Intake3.43.84.8-1.9-2.0-2.1-2.0-1.9-2.0-2.0-1.6-2.2-1.6
Incentive Sensitization - Responses3.53.54.2-1.9-1.9-2.1-2.0-1.9-1.8-1.8-1.9-1.8-1.6
Incentive Sensitization - Breakpoint3.33.33.8-1.9-1.9-2.0-2.0-1.9-1.7-1.7-1.8-1.7-1.6
Progressive ratio test 1 active lever presses4.85.05.6-2.3-2.4-2.3-2.3-2.3-2.2-2.2-2.1-2.4-1.8
Progressive ratio test 1 breakpoint6.26.47.3-2.6-2.6-2.7-2.6-2.6-2.5-2.5-2.4-2.7-2.0
Progressive ratio test 1 inactive lever presses5.05.46.5-2.4-2.4-2.3-2.4-2.4-2.4-2.3-2.6-2.4-1.7
Progressive ratio test 2 active lever presses5.66.07.1-2.5-2.5-2.7-2.5-2.5-2.3-2.5-2.1-2.6-2.2
Progressive ratio test 2 breakpoint6.87.69.0-2.9-2.7-3.0-2.8-2.8-2.7-2.7-2.4-2.9-2.5
Progressive ratio test 2 inactive lever presses4.55.26.8-2.2-2.3-2.5-2.2-2.2-2.2-2.5-1.9-2.6-2.1
Total sessions with >9 infusions0.10.10.3-0.1-0.3-0.4-0.2-0.3-0.2-0.5-0.4-0.5-0.0
Short access day 1 total inactive lever presses1.31.41.8-1.3-1.2-1.2-1.2-1.4-1.2-1.0-0.8-1.2-1.4
Short access day 10 total inactive lever presses0.70.81.5-0.6-0.7-1.0-0.8-0.8-1.0-1.0-1.0-1.2-0.6
Short access day 1 total infusions0.80.81.2-0.9-0.9-1.0-0.9-0.8-0.9-1.0-1.1-1.1-0.4
Short access day 10 total infusions6.67.29.1-2.6-2.7-2.9-2.7-2.6-2.8-2.7-2.4-3.0-2.3
Short access total infusions3.84.24.9-2.1-2.1-2.1-2.1-2.0-2.2-2.1-1.8-2.2-1.6
Short access day 1 locomotion3.33.55.3-1.8-1.7-2.3-1.8-1.9-1.7-2.0-1.5-2.1-1.7
Short access day 10 total locomotion10.811.815.0-3.3-3.6-3.9-3.6-3.4-3.3-3.6-2.2-3.5-3.7
Short access total locomotion5.25.47.5-2.3-2.4-2.7-2.5-2.3-2.3-2.4-1.3-2.4-2.2
Compulsive drug intake0.80.81.50.70.91.10.90.80.91.20.51.00.6
One hour access (0.3 mA shock)1.01.21.6-1.1-1.2-1.2-1.3-1.1-1.2-0.8-1.0-1.1-0.6
One hour access (shock baseline)1.21.41.9-1.0-1.3-1.4-1.3-1.1-1.3-1.2-1.0-1.3-0.6
Number of responses in last shaping day1.51.52.1-1.4-1.1-1.4-1.3-1.3-1.4-0.9-1.0-1.4-1.0
Context. condit. distance diff. score0.60.81.50.90.60.50.50.91.10.90.61.21.2
Locomotion velocity, session 11.92.14.1-1.5-1.4-1.2-1.3-1.6-1.4-1.5-0.8-1.4-2.0
Locomotion distance, session 10.20.21.1-0.2-0.3-0.2-0.1-0.4-0.2-0.6-0.3-0.5-1.0
Locomotion velocity, session 21.01.22.1-1.2-1.2-0.5-1.2-1.1-1.5-1.0-1.1-0.8-1.1
Locomotion distance, session 20.00.10.20.1-0.30.3-0.10.0-0.1-0.1-0.50.2-0.3
Locomotion velocity, session 30.10.10.30.30.30.50.40.40.00.50.20.10.1
Locomotion distance, session 30.10.10.4-0.3-0.40.0-0.3-0.3-0.60.0-0.6-0.4-0.3
Stereotopy head waving bouts, day 30.10.20.40.20.60.50.60.20.3-0.00.70.0-0.2
Stereotopy head waving duration, day 30.30.40.70.60.80.60.70.60.80.40.70.50.5
Locomotion velocity, session 70.30.30.60.60.50.60.60.60.50.30.80.50.2
Locomotion distance, session 70.10.10.30.40.10.20.30.40.50.1-0.30.50.4
Stereotopy head waving bouts, day 70.10.10.50.10.40.70.40.20.10.20.40.30.1
Stereotopy head waving duration, day 71.11.43.00.91.11.71.11.10.81.11.21.21.1
Locomotion velocity, session 80.20.20.7-0.2-0.8-0.6-0.8-0.2-0.5-0.1-0.5-0.2-0.1
Locomotion distance, session 80.10.20.50.50.00.30.10.50.50.3-0.10.70.7
Degree of sensitization distance0.10.10.50.4-0.0-0.20.10.30.7-0.2-0.20.50.3
Degree of sensitization stereotypy0.60.61.40.60.61.20.70.70.50.90.80.90.6
Condit. Reinf. active minus inactive responses3.33.74.7-2.2-2.0-1.9-2.1-2.1-1.8-1.9-1.8-1.6-1.8
Condit. Reinf. active-inactive response ratio1.31.42.4-1.6-1.3-1.1-1.4-1.4-1.0-1.2-1.1-0.7-1.0
Condit. Reinf. active responses3.94.75.4-2.2-2.3-2.1-2.3-2.2-2.2-2.2-2.3-2.0-1.9
Condit. Reinf. inactive responses1.21.52.3-0.9-1.2-1.1-1.1-1.0-1.3-1.3-1.5-1.5-1.1
Incentive salience index mean3.84.65.6-2.4-2.2-1.8-2.2-2.2-2.3-2.1-1.9-2.0-2.2
Condit. Reinf. lever presses0.91.22.4-1.0-1.2-0.6-1.1-0.8-1.5-1.1-0.9-1.2-1.1
Time in familiar zone, hab. session 10.20.20.80.0-0.7-0.6-0.5-0.0-0.2-0.3-0.9-0.20.1
Time in novel zone, hab. session 10.50.51.20.21.00.80.90.30.50.61.10.50.1
Total zone transitions, hab. session 10.10.10.50.1-0.5-0.4-0.30.1-0.2-0.2-0.3-0.3-0.7
Total locomotion distance, hab. session 11.21.84.4-1.0-1.4-1.1-1.0-1.1-1.3-1.5-1.0-1.5-2.1
Locomotion velocity, hab. session 11.52.24.5-1.1-1.6-1.3-1.3-1.2-1.4-1.6-1.2-1.6-2.1
Time in familiar zone, hab. session 20.50.51.2-0.6-1.0-0.9-1.1-0.5-0.4-0.5-1.1-0.0-0.3
Time in novel zone, hab. session 20.40.41.10.41.00.81.10.30.30.30.9-0.10.1
Total zone transitions, hab. session 20.00.00.20.4-0.20.1-0.00.40.00.0-0.00.1-0.1
Total locomotion distance, hab. session 20.30.41.1-0.1-0.6-0.5-0.4-0.2-0.4-1.1-0.5-0.7-0.9
Locomotion velocity, hab. session 20.20.30.90.0-0.6-0.4-0.3-0.1-0.3-1.0-0.6-0.6-0.8
Novel to familiar place preference ratio0.40.40.7-0.8-0.4-0.8-0.6-0.9-0.6-0.5-0.4-0.8-0.4
Novelty place preference0.20.20.4-0.6-0.2-0.5-0.4-0.7-0.4-0.3-0.2-0.5-0.2
Time in novel zone, NPP test0.10.10.4-0.6-0.2-0.4-0.3-0.6-0.4-0.2-0.1-0.4-0.2
Total zone transitions, NPP test0.00.10.20.3-0.20.10.10.1-0.0-0.3-0.4-0.2-0.4
Total locomotion distance, NPP test0.71.02.4-0.6-1.1-0.7-0.7-0.8-0.9-1.4-0.9-1.1-1.5
Locomotion velocity, NPP test0.40.51.3-0.2-0.7-0.6-0.4-0.4-0.5-1.1-0.7-0.9-1.1
Pavlov. Cond. lever latency3.74.77.12.22.21.72.12.02.72.01.92.42.4
Pavlov. Cond. magazine entry latency5.67.29.6-2.7-2.7-2.2-2.6-2.6-3.1-2.6-2.7-2.9-2.7
Pavlov. Cond. change in total contacts5.15.58.0-2.4-2.3-2.0-2.3-2.2-2.8-2.3-1.9-2.6-2.4
Pavlov. Cond. index score5.06.49.0-2.6-2.5-2.1-2.5-2.4-3.0-2.4-2.5-2.8-2.4
Pavlov. Cond. latency score3.95.07.3-2.3-2.3-1.8-2.3-2.1-2.7-2.0-2.2-2.5-2.2
Pavlov. Cond. lever contacts3.13.75.9-2.0-2.0-1.6-2.0-1.8-2.4-1.7-1.5-2.1-2.1
Pavlov. Cond. magazine entry number4.55.67.52.52.31.92.32.32.72.42.22.62.4
Pavlov. Cond. intertrial magazine entries0.30.41.1-0.3-0.6-1.0-0.6-0.5-0.2-0.7-1.1-0.60.0
Pavlov. Cond. lever-magazine prob. diff.4.86.08.8-2.5-2.4-2.0-2.4-2.3-3.0-2.2-2.4-2.8-2.4
Pavlov. Cond. response bias6.68.111.5-3.0-2.7-2.2-2.7-2.8-3.4-2.7-2.5-3.2-3.0
Bone: apparent density3.05.07.4-2.4-1.9-1.6-1.8-2.4-2.4-2.4-1.7-2.7-2.7
Bone surface9.015.919.2-4.3-3.9-3.3-3.8-4.3-4.4-3.6-3.7-4.3-4.2
Bone volume7.512.716.0-3.8-3.4-3.0-3.3-3.8-3.9-3.4-3.2-4.0-3.8
Bone: connectivity density3.96.18.0-2.7-2.3-1.8-2.1-2.7-2.6-2.6-2.2-2.7-2.8
Bone: cortical apparent density4.66.08.32.62.82.52.92.62.61.72.52.02.0
Bone: cortical area3.04.57.4-2.2-1.8-2.0-1.8-2.2-2.4-1.9-1.8-2.7-2.3
Bone: cortical porosity14.715.922.1-4.5-4.0-3.7-4.2-4.3-4.7-3.0-3.2-3.9-4.1
Bone: cortical porosity9.09.713.5-3.5-3.0-2.9-3.2-3.3-3.7-2.1-2.6-3.2-3.3
Bone: cortical thickness1.62.64.91.52.21.72.21.61.21.42.20.50.6
Bone: cortical thickness1.41.73.21.01.61.61.71.11.01.11.80.90.6
Bone: cortical tissue density4.55.98.02.62.82.52.82.62.61.72.52.02.0
Bone: elastic displacement0.80.91.70.81.11.11.00.80.81.11.30.80.3
Bone: elastic work0.40.52.1-0.7-0.3-0.5-0.4-0.7-0.8-0.60.3-1.0-1.4
Bone: endosteal estimation16.535.541.4-6.3-6.4-5.9-6.4-6.3-6.0-5.4-6.0-5.4-5.4
Bone: endosteal perimeter17.636.242.5-6.3-6.4-6.1-6.5-6.3-6.0-5.1-6.4-5.6-5.2
Bone: final force1.42.23.8-1.6-1.2-1.1-1.2-1.6-1.6-1.2-1.4-1.8-1.9
Bone: final moment1.62.64.6-1.7-1.3-1.2-1.3-1.7-1.8-1.3-1.4-1.9-2.1
Bone: marrow area16.134.740.5-6.2-6.3-5.8-6.4-6.2-6.0-5.3-5.9-5.3-5.3
Bone: maximum diameter7.112.915.3-3.8-3.5-3.4-3.6-3.8-3.9-3.0-3.7-3.9-3.3
Bone: maximum force2.34.05.8-1.9-1.8-1.9-1.7-2.0-2.0-1.7-2.1-2.4-2.3
Bone: maximum moment2.54.46.5-2.0-1.9-2.0-1.8-2.2-2.2-1.9-2.0-2.6-2.5
Bone: minimum diameter15.127.930.0-5.4-5.4-5.5-5.5-5.5-5.4-4.7-5.1-5.4-4.9
Bone: periosteal estimation13.026.629.8-5.5-5.1-5.0-5.2-5.5-5.4-4.7-4.9-5.3-5.0
Bone: periosteal perimeter7.512.514.9-3.9-3.4-3.4-3.6-3.9-3.8-2.7-3.7-3.7-3.3
Bone: post-yield work2.33.24.1-1.8-2.0-2.0-2.0-1.8-1.8-1.2-1.9-1.7-1.5
Bone: stiffness0.60.92.5-0.7-1.1-0.8-0.9-0.8-1.0-0.7-1.6-1.0-0.7
Bone: tissue strength1.31.21.71.31.11.31.21.21.11.30.71.00.9
Bone: trabecular number4.06.38.1-2.7-2.3-1.8-2.1-2.7-2.7-2.6-2.3-2.8-2.8
Bone: trabecular spacing1.72.23.61.61.21.01.01.61.61.61.31.81.9
Bone: trabecular thickness5.87.011.3-2.7-2.2-2.3-2.1-2.8-3.0-2.6-2.0-3.4-3.0
Bone: trabecular tissue density0.81.12.31.11.41.11.50.91.30.80.70.70.6
Breakpoint value in progressive ratio session1.01.11.6-1.2-1.2-0.9-1.3-1.2-1.1-0.8-1.1-0.7-0.6
Distance traveled before self-admin0.20.31.5-0.00.40.30.10.1-0.31.2-0.80.10.4
Distance traveled after self-admin0.20.21.2-0.10.10.2-0.20.00.01.1-0.70.60.3
Delta time in closed arm before/after self-admin0.10.10.5-0.3-0.30.1-0.3-0.2-0.30.0-0.7-0.0-0.5
Delta time in open arm before/after self-admin0.80.71.80.90.90.50.90.90.90.40.80.61.3
Diff in mean of infusions in LGA sessions0.91.01.41.11.00.91.01.21.01.10.80.91.0
Extinction: sum of active levers before priming0.10.10.2-0.2-0.2-0.4-0.3-0.3-0.0-0.2-0.3-0.10.5
Active lever presses in extinction session 63.02.93.9-1.7-1.7-1.8-1.8-1.8-2.0-1.5-1.3-1.9-1.4
Delta distance traveled before/after self-admin0.30.41.00.40.40.50.40.40.80.40.91.00.3
Delta ambulatory time before/after self-admin0.00.10.2-0.0-0.10.1-0.0-0.00.4-0.30.10.5-0.3
Time in closed arm before self-admin0.70.82.50.60.81.10.80.70.60.71.60.90.4
Time in closed arm after self-admin0.80.82.00.70.61.30.70.80.81.10.81.40.4
Time in open arm before self-admin0.30.41.30.50.60.40.40.60.61.20.10.80.3
Time in open arm after self-admin0.10.10.40.00.1-0.6-0.1-0.00.10.0-0.2-0.40.4
Sum of active levers in priming session hrs 5-60.50.51.70.60.60.60.50.60.60.60.40.71.3
Time to tail flick, vehicle, before self-admin0.10.11.0-0.20.20.20.1-0.2-0.00.6-1.00.0-0.1
Time to tail flick, vehicle, after self-admin0.60.71.3-0.8-0.5-0.9-0.6-0.9-0.7-0.8-1.0-1.1-0.6
Time to tail flick, test, before self-admin0.70.71.20.80.70.70.70.90.71.01.11.00.6
Time to tail flick, test, after self-admin0.00.00.10.10.30.20.30.1-0.20.20.2-0.2-0.1
Delta time to tail flick, vehicle, before/after SA2.01.93.9-1.3-1.3-1.4-1.2-1.3-1.4-2.0-0.6-1.7-1.2
Delta time to tail flick, test, before/after SA0.10.10.2-0.0-0.00.10.0-0.1-0.4-0.2-0.4-0.40.0
Ambulatory time before self-admin0.20.21.0-0.20.10.1-0.1-0.1-0.31.0-0.60.00.4
Ambulatory time after self-admin0.20.31.1-0.6-0.4-0.3-0.5-0.5-0.40.3-1.00.1-0.5
Total heroin consumption0.80.91.6-1.2-1.0-0.6-1.1-1.1-1.2-0.6-1.0-0.8-0.7
Area under the delay curve0.10.10.3-0.1-0.0-0.3-0.0-0.3-0.1-0.2-0.5-0.4-0.3
Delay disc. indifference point, 0s delay0.60.61.00.91.00.91.00.80.80.80.40.60.6
Delay disc. indifference point, 16s delay0.40.41.0-0.5-0.3-0.8-0.4-0.7-0.5-0.5-1.0-0.9-0.6
Delay disc. indifference point, 2s delay0.40.51.4-0.5-0.5-0.3-0.4-0.7-0.5-0.8-1.2-0.9-0.5
Delay disc. indifference point, 24s delay1.61.62.7-0.9-1.0-1.5-1.0-1.2-0.9-1.2-1.6-1.5-1.3
Delay disc. indifference point, 4s delay0.30.30.60.50.70.70.60.50.40.80.50.40.3
Delay disc. indifference point, 8s delay0.10.10.30.30.50.30.50.20.3-0.1-0.1-0.1-0.1
Delay discount exponential model param0.20.20.50.30.30.50.30.50.30.40.70.60.4
Delay discount hyperbolic model param0.10.10.40.20.10.30.10.30.20.40.60.50.3
Fecal boli incidents, locomotor time 10.10.10.20.10.2-0.10.00.10.10.5-0.50.10.2
Change in fecal boli incidents, locomotor task0.30.30.60.60.60.20.70.50.80.30.30.30.7
Time >=10cm from walls, locomotor time 12.92.95.11.51.51.91.51.71.52.21.11.92.0
Bouts of movement, locomotor time 10.40.41.20.60.70.40.70.60.80.21.10.50.2
Total resting periods, locomotor time 10.40.40.90.70.80.40.80.70.80.20.90.40.0
Rest time, locomotor task time 10.10.10.20.10.40.40.40.10.2-0.10.10.1-0.2
Distance moved, locomotor task time 10.40.40.7-0.5-0.9-0.9-0.8-0.5-0.6-0.7-0.3-0.7-0.7
Vertical activity count, locomotor time 10.40.40.6-0.6-0.8-0.7-0.7-0.6-0.8-0.5-0.6-0.8-0.5
Time >=10cm from walls, locomotor time 20.10.10.3-0.4-0.10.2-0.1-0.2-0.30.40.60.20.0
Bouts of movement, locomotor time 20.20.20.50.50.70.20.60.40.40.30.60.20.6
Total resting periods, locomotor time 20.60.61.00.81.00.50.90.70.80.60.90.60.9
Rest time, locomotor task time 24.04.76.32.12.52.12.32.12.32.21.62.12.1
Distance moved, locomotor task time 20.91.11.7-1.0-1.3-0.9-1.1-0.8-1.2-1.1-0.0-0.9-1.3
Vertical activity count, locomotor time 24.54.96.4-2.3-2.4-2.1-2.3-2.2-2.5-2.4-1.2-2.2-2.3
Weight adjusted by age1.01.11.91.11.10.81.01.01.11.30.40.91.4
Seeking ratio, delayed vs. immediate footshock0.10.10.30.1-0.0-0.30.00.20.4-0.00.50.40.0
Locomotion in novel chamber0.10.10.5-0.0-0.10.1-0.10.00.20.7-0.20.5-0.0
Locomotion in novel chamber post-restriction1.72.13.3-1.6-1.3-1.4-1.4-1.5-1.4-1.2-1.8-1.5-1.2
Progressive ratio0.10.10.20.50.30.30.30.30.20.5-0.00.30.4
Food seeking constrained by brief footshock2.53.14.8-1.7-2.2-1.8-2.1-1.7-1.7-1.6-1.5-1.3-1.7
Seeking ratio, punishment vs. effort1.31.62.2-1.3-1.5-1.3-1.5-1.2-1.2-1.3-1.0-1.0-1.3
Run reversals in cocaine runway, females0.20.20.90.50.5-0.20.50.30.10.11.0-0.4-0.4
Run reversals in cocaine runway, males0.00.00.2-0.00.30.00.10.00.00.5-0.20.1-0.1
Latency to leave start box in cocaine runway0.30.30.50.30.70.50.50.50.50.70.20.70.4
Latency to leave start box in cocaine runway, F0.40.51.40.40.90.70.70.60.51.20.50.80.4
Latency to leave start box in cocaine runway, M0.10.10.10.10.10.20.20.10.4-0.20.20.40.2
Cd content in liver5.46.09.02.42.32.32.32.52.92.22.23.02.1
Co content in liver0.91.11.91.00.80.90.61.21.01.11.11.41.2
Cu content in liver0.50.51.0-0.7-0.5-0.7-0.6-0.8-0.9-1.0-0.3-1.0-0.6
Fe content in liver0.20.20.50.30.50.70.50.40.40.20.10.60.6
K content in liver1.21.23.1-0.9-1.2-0.5-1.1-0.8-1.5-0.8-1.7-1.3-0.3
Mg content in liver0.10.10.40.1-0.20.3-0.00.2-0.4-0.5-0.6-0.30.5
Mn content in liver0.20.30.7-0.2-0.40.4-0.1-0.2-0.8-0.6-0.8-0.8-0.2
Na content in liver0.50.61.9-0.8-0.7-0.2-0.8-0.6-1.0-0.5-1.4-0.70.1
Rb content in liver3.03.86.12.01.92.52.02.11.61.81.31.92.2
Se content in liver1.92.33.61.51.61.51.41.61.61.50.61.51.9
Sr content in liver0.70.61.1-0.9-0.6-0.8-0.7-0.9-0.8-0.5-0.5-0.9-1.0
Zn content in liver0.10.10.5-0.4-0.00.0-0.2-0.3-0.2-0.1-0.7-0.3-0.1