Hub : Genes

Plpp3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000008116 0.19 0.14 1.7e-07 0.05 0.04 0.05 0.04 7.8e-06 9.6e-06 3.2e-06 1.0e-05
2 Adipose mRNA stability ENSRNOG00000008116 0.12 0.1 6.1e-10 0.07 0.06 0.07 0.06 7.1e-08 2.0e-07 7.0e-08 9.6e-08
3 Brain gene expression ENSRNOG00000008116 0.36 0.38 3.8e-12 0.14 0.13 0.14 0.14 4.3e-13 2.8e-12 9.9e-13 6.2e-13
4 Brain mRNA stability ENSRNOG00000008116 0.73 0.13 4.7e-14 0.14 0.15 0.16 0.14 7.8e-13 4.7e-14 3.3e-14 1.4e-12
5 LHb gene expression ENSRNOG00000008116 0.2 0.18 2.0e-03 0.1 0.09 0.11 0.09 2.4e-03 4.6e-03 1.6e-03 4.1e-03
6 Liver gene expression ENSRNOG00000008116 0.46 0.16 0.0e+00 0.39 0.41 0.41 0.41 1.1e-45 3.4e-49 2.2e-48 1.6e-48
7 Liver mRNA stability ENSRNOG00000008116 0.14 0.14 6.7e-09 0.06 0.06 0.06 0.06 1.4e-07 9.8e-08 1.2e-07 1.5e-07
8 NAcc gene expression ENSRNOG00000008116 0.12 0.12 8.7e-07 0.05 0.07 0.07 0.07 7.8e-05 9.9e-06 1.1e-05 6.4e-06
9 NAcc mRNA stability ENSRNOG00000008116 0.03 0.04 8.1e-03 0.02 0.02 0.01 0.02 2.0e-02 1.0e-02 3.9e-02 1.4e-02
10 PL gene expression ENSRNOG00000008116 0.09 0.08 1.9e-05 0.05 0.05 0.05 0.05 2.0e-04 1.8e-04 2.0e-04 1.5e-04
11 PL mRNA stability ENSRNOG00000008116 0.06 0.07 8.9e-04 0.02 0.03 0.01 0.02 6.5e-03 4.0e-03 8.2e-02 6.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.30.91.3-1.01.01.20.90.90.90.90.90.90.90.9
BMI without tail0.10.20.40.6-0.3-0.0-0.3-0.5-0.6-0.7-0.6-0.6-0.4-0.6
Body weight0.10.60.8-0.80.70.80.40.80.70.70.70.80.90.8
Epididymis fat weight0.20.50.80.7-0.7-0.9-0.7-0.7-0.7-0.5-0.9-0.7-0.9-0.7
Glucose0.00.00.10.10.00.2-0.0-0.1-0.0-0.1-0.3-0.1-0.1-0.1
Heart weight0.91.32.0-1.21.21.00.81.31.31.41.01.30.91.3
Left kidney weight8.524.326.5-5.14.95.14.44.94.94.95.04.95.14.9
Right kidney weight5.816.518.0-4.24.04.03.34.14.14.04.24.24.24.2
Tail length0.30.81.50.8-0.8-0.8-1.2-0.8-0.9-1.0-0.9-0.9-0.7-0.9
Length with tail0.00.00.2-0.2-0.1-0.2-0.40.20.1-0.00.00.10.30.1
Length without tail1.02.32.7-1.61.31.11.31.61.61.61.51.61.51.6
Liver weight, left0.10.20.6-0.40.40.50.40.40.40.40.50.40.70.4
Liver weight, right2.13.44.2-1.91.81.81.61.81.81.82.01.82.01.8
Parametrial fat weight0.61.21.6-1.31.01.00.71.11.11.01.11.11.21.1
Retroperitoneal fat weight0.20.51.20.5-0.8-1.1-0.9-0.6-0.6-0.7-0.6-0.6-0.7-0.6
Intraocular pressure0.10.10.8-0.10.2-0.10.90.20.40.60.30.30.00.3
Extensor digitorum longus weight4.819.322.2-4.44.54.74.04.34.44.44.34.44.44.4
Soleus weight0.00.10.4-0.10.20.30.00.20.20.10.30.20.70.2
Tibialis anterior weight1.86.27.3-2.52.62.72.22.52.52.52.42.62.42.6
Tibia length0.00.10.20.3-0.4-0.3-0.5-0.3-0.4-0.4-0.1-0.4-0.1-0.4
Number of licking bursts0.00.00.10.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Food consumed during 24 hour testing period1.51.92.31.2-1.4-1.3-1.3-1.4-1.4-1.5-1.5-1.4-1.0-1.4
Times rat made contact with spout0.10.10.3-0.40.40.50.30.30.30.30.30.30.60.3
Mean time between licks in bursts0.10.20.20.2-0.5-0.4-0.4-0.4-0.5-0.5-0.3-0.5-0.0-0.4
Mean num. licks in bursts0.50.60.8-0.80.80.90.80.70.80.80.70.70.90.7
Std. dev. time between licks in bursts0.91.11.90.8-1.2-1.4-1.1-1.0-1.1-1.2-0.8-1.1-0.5-1.0
Water consumed over 24 hours2.42.93.5-1.71.71.91.61.71.71.61.51.71.81.6
Indifference point 0 sec0.71.11.51.1-1.0-1.1-0.9-1.0-1.0-0.9-1.1-1.1-1.2-1.1
Indifference point AUC0.81.01.31.1-0.9-0.7-0.9-1.0-1.1-1.1-0.9-1.0-0.9-1.0
Indifference point function ln k0.60.81.0-0.80.90.70.81.01.01.01.01.00.81.0
Indifference point function log k0.60.81.0-0.80.90.70.81.01.01.01.01.00.81.0
Delay discounting total patch changes 0 sec0.50.81.21.0-0.9-0.9-0.8-0.9-0.9-0.8-1.0-0.9-1.1-0.9
Delay discounting total patch changes 12 sec1.62.12.61.6-1.3-1.3-1.6-1.4-1.4-1.3-1.6-1.5-1.6-1.5
Delay discounting total patch changes 18 sec0.40.60.80.7-0.7-0.6-0.8-0.8-0.8-0.9-0.7-0.8-0.6-0.8
Delay discounting total patch changes 24 sec0.50.60.90.8-0.8-0.6-0.9-0.7-0.8-0.8-0.9-0.8-0.8-0.7
Delay discounting total patch changes 6 sec0.10.20.30.4-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.5-0.5-0.5
Delay discounting time to switch 0 sec1.11.61.91.1-1.3-1.3-1.2-1.3-1.3-1.3-1.4-1.3-1.3-1.3
Delay discounting water rate 0 sec1.52.32.8-1.41.61.61.21.61.51.51.71.61.61.6
Delay discounting water rate 12 sec2.03.03.7-1.91.61.51.31.81.81.61.91.81.81.9
Delay discounting water rate 18 sec0.10.11.00.1-0.3-0.4-1.0-0.2-0.2-0.20.0-0.1-0.1-0.1
Delay discounting water rate 24 sec1.92.63.3-1.81.51.31.31.71.61.41.71.71.81.7
Delay discounting water rate 6 sec0.00.00.2-0.00.10.0-0.50.10.10.00.20.10.10.2
Locomotor activity0.10.10.2-0.30.20.1-0.10.40.30.30.40.40.20.3
Locomotor testing distance0.20.30.4-0.50.50.60.40.60.50.50.60.60.30.6
Locomotor testing rearing0.30.50.6-0.60.70.70.60.70.70.70.70.70.60.7
Light reinforcement 10.30.50.70.7-0.7-0.6-0.4-0.7-0.7-0.8-0.8-0.7-0.8-0.7
Light reinforcement 21.01.31.9-1.21.21.31.01.21.21.40.91.20.91.2
Reaction time number correct0.50.71.00.8-0.8-1.0-1.0-0.8-0.8-0.8-0.8-0.8-0.7-0.8
Reaction time mean minus median1.01.31.51.2-1.1-1.2-0.9-1.1-1.1-1.1-1.1-1.2-1.2-1.2
Reaction time mean minus median AUC0.10.10.40.5-0.3-0.3-0.0-0.3-0.3-0.1-0.5-0.4-0.6-0.4
Reaction time num false alarms0.30.40.5-0.60.60.40.20.70.70.70.60.70.60.7
Reaction time num false alarms AUC0.40.60.9-0.80.70.50.20.90.90.90.80.90.70.9
Reaction time trials correct on left0.50.71.00.8-0.8-1.0-1.0-0.8-0.8-0.8-0.8-0.8-0.7-0.8
Reaction time trials on left0.50.71.00.8-0.8-0.9-1.0-0.8-0.8-0.8-0.8-0.8-0.7-0.8
Reaction time mean0.60.81.10.9-0.9-0.9-0.7-0.9-0.9-0.8-0.8-0.9-1.0-0.9
Reaction time mean AUC0.50.71.10.9-0.9-0.9-0.6-0.9-0.8-0.8-0.8-0.9-1.0-0.9
Median of all reaction times0.91.21.61.1-1.1-1.1-1.1-1.1-1.1-1.0-1.1-1.1-1.3-1.1
Reaction time omissions0.00.00.00.00.00.0-0.0-0.10.00.00.10.0-0.00.0
Reaction time false alarm rate1.21.72.0-1.41.31.11.01.41.41.41.31.41.21.4
Reaction time premature initiation rate0.60.81.2-1.10.70.50.40.90.90.90.90.91.10.9
Reaction time premature initiations0.10.10.2-0.40.1-0.2-0.30.30.30.30.30.30.50.3
Std. dev. reaction times0.20.30.40.5-0.6-0.6-0.6-0.5-0.5-0.4-0.3-0.5-0.5-0.4
Reaction time trials completed0.50.71.00.8-0.8-0.9-1.0-0.8-0.8-0.8-0.8-0.8-0.7-0.8
Reaction time trials AUC0.50.71.00.8-0.8-0.9-1.0-0.8-0.8-0.8-0.8-0.8-0.7-0.8
Social response proportion0.40.50.80.7-0.6-0.8-0.5-0.6-0.6-0.5-0.9-0.7-0.9-0.7
Social responses2.73.54.31.9-1.8-1.9-1.6-1.8-1.8-1.6-2.1-1.9-2.1-1.9
Social time0.50.61.0-0.70.80.50.90.90.91.00.80.90.50.9
Conditioned locomotion0.00.00.10.2-0.00.10.0-0.2-0.2-0.1-0.2-0.2-0.1-0.2
Cocaine response after cond. corrected2.42.74.2-1.51.82.11.51.61.71.71.61.61.51.6
Cocaine response after cond. not corrected1.82.03.0-1.11.51.71.31.41.51.51.41.41.21.4
Cocaine response before conditioning1.62.02.51.6-1.4-1.5-1.3-1.3-1.3-1.2-1.5-1.3-1.6-1.3
Saline control response0.10.10.2-0.30.30.40.30.30.40.40.30.40.20.4
Condit. Reinf. active minus inactive responses0.20.30.40.4-0.5-0.6-0.5-0.4-0.5-0.5-0.6-0.4-0.6-0.4
Condit. Reinf. active-inactive response ratio0.80.80.90.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9
Condit. Reinf. active responses0.00.00.00.0-0.0-0.1-0.00.00.00.1-0.20.0-0.20.0
Condit. Reinf. inactive responses0.50.70.9-0.80.80.70.80.90.91.00.70.90.70.9
Condit. Reinf. lever presses6.69.011.73.0-3.0-3.2-2.9-2.9-2.9-2.9-3.0-2.9-3.4-2.9
Condit. Reinf. lever reinforcers received0.10.20.30.4-0.4-0.6-0.4-0.3-0.3-0.3-0.5-0.3-0.5-0.3
Pavlov. Cond. lever latency9.913.515.0-3.83.73.83.53.63.63.63.73.63.93.6
Pavlov. Cond. magazine entry latency8.19.310.23.0-3.1-3.2-3.1-3.0-3.1-3.1-2.9-3.0-3.0-3.0
Pavlov. Cond. change in total contacts8.612.013.23.4-3.5-3.6-3.3-3.4-3.4-3.5-3.5-3.4-3.6-3.4
Pavlov. Cond. index score9.312.113.53.5-3.5-3.7-3.4-3.4-3.4-3.4-3.4-3.4-3.7-3.4
Pavlov. Cond. latency score9.812.513.93.6-3.6-3.7-3.5-3.5-3.5-3.5-3.5-3.4-3.7-3.4
Pavlov. Cond. lever contacts8.211.413.83.5-3.3-3.5-3.2-3.3-3.3-3.2-3.4-3.3-3.7-3.3
Pavlov. Cond. magazine entry number4.75.76.4-2.42.42.52.42.42.42.42.32.32.52.3
Pavlov. Cond. intertrial magazine entries0.91.11.2-1.11.11.11.01.11.11.10.91.11.01.1
Pavlov. Cond. lever-magazine prob. diff.9.512.213.53.5-3.5-3.7-3.4-3.4-3.5-3.5-3.4-3.4-3.6-3.4
Pavlov. Cond. response bias7.510.312.63.4-3.2-3.3-3.1-3.2-3.2-3.1-3.2-3.1-3.5-3.1
Conditioned reinforcement - actives0.60.60.8-0.70.90.80.60.70.80.90.70.80.70.8
Conditioned reinforcement - inactives0.10.10.2-0.40.40.40.50.30.40.40.30.30.30.3
Conditioned locomotion0.80.91.1-1.01.01.00.80.91.01.10.90.91.00.9
Intermittent access intake day 1-15 change0.70.71.10.7-0.9-0.9-1.0-0.9-0.9-0.9-0.7-0.8-0.7-0.8
Intermittent access intake escalation0.70.70.90.7-0.9-0.9-1.0-0.8-0.8-0.9-0.7-0.8-0.7-0.8
Intermittent access intake escalation 22.12.12.51.3-1.5-1.5-1.3-1.5-1.5-1.6-1.3-1.5-1.3-1.5
Intermitt. access day 1 inactive lever presses7.07.68.8-3.02.62.62.32.82.82.73.02.83.02.8
Intermitt. access day 15 inactive lever presses0.20.30.6-0.60.40.60.70.40.40.30.60.50.60.5
Intermitt. access escalation Index1.61.53.01.0-1.3-1.2-1.7-1.2-1.2-1.3-1.0-1.1-1.0-1.1
Intermittent access day 1 total infusions0.10.10.2-0.20.30.30.20.20.30.40.20.20.10.2
Intermittent access day 15 total infusions0.10.10.30.3-0.3-0.4-0.6-0.4-0.3-0.3-0.3-0.4-0.3-0.4
Intermittent access terminal intake (last 3 days)0.20.20.30.3-0.4-0.5-0.5-0.5-0.4-0.4-0.4-0.4-0.4-0.5
Intermittent access total infusions0.00.00.0-0.20.1-0.0-0.20.00.10.10.10.10.10.1
Intermittent access day 1 locomotion0.00.00.00.0-0.0-0.1-0.0-0.00.00.1-0.1-0.0-0.0-0.0
Intermittent access day 15 total locomotion0.40.50.60.7-0.6-0.6-0.5-0.7-0.6-0.5-0.8-0.7-0.8-0.8
Intermittent access total locomotion0.40.50.60.7-0.6-0.7-0.4-0.8-0.7-0.6-0.8-0.8-0.8-0.8
Intermittent access standard deviation0.20.30.7-0.50.50.50.80.40.50.50.40.40.40.4
Cocaine induced anxiety0.20.30.40.5-0.4-0.5-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.5
Post-drug Anxiety0.10.10.20.3-0.3-0.1-0.0-0.3-0.4-0.5-0.3-0.4-0.3-0.4
Baseline Anxiety1.61.73.5-1.31.21.51.91.21.21.01.31.21.31.2
Lifetime Intake0.00.00.1-0.0-0.0-0.1-0.3-0.1-0.00.0-0.0-0.00.0-0.0
Incentive Sensitization - Responses5.75.66.52.4-2.5-2.1-2.1-2.5-2.4-2.6-2.4-2.4-2.4-2.4
Incentive Sensitization - Breakpoint5.35.36.12.3-2.4-2.0-2.0-2.4-2.4-2.5-2.3-2.3-2.3-2.3
Progressive ratio test 1 active lever presses0.20.20.40.4-0.4-0.6-0.6-0.4-0.4-0.3-0.5-0.4-0.5-0.4
Progressive ratio test 1 breakpoint0.20.20.40.4-0.4-0.6-0.6-0.4-0.4-0.3-0.4-0.4-0.4-0.4
Progressive ratio test 1 inactive lever presses0.20.20.5-0.30.40.40.70.30.40.50.30.30.30.3
Progressive ratio test 2 active lever presses1.21.31.51.1-1.2-1.0-1.0-1.2-1.2-1.2-1.1-1.2-1.1-1.1
Progressive ratio test 2 breakpoint1.11.21.51.0-1.2-1.0-1.0-1.2-1.1-1.2-1.1-1.1-1.1-1.1
Progressive ratio test 2 inactive lever presses0.00.00.00.0-0.10.0-0.1-0.1-0.00.0-0.1-0.1-0.1-0.0
Total sessions with >9 infusions2.32.55.41.4-1.6-1.7-2.3-1.5-1.5-1.5-1.4-1.4-1.4-1.4
Short access day 1 total inactive lever presses1.61.71.9-1.31.31.41.31.31.31.31.31.31.31.3
Short access day 10 total inactive lever presses6.57.28.1-2.82.62.72.52.62.62.52.82.72.82.7
Short access day 1 total infusions0.00.00.00.20.10.1-0.2-0.00.00.1-0.2-0.0-0.2-0.0
Short access day 10 total infusions0.20.20.60.3-0.4-0.5-0.7-0.4-0.4-0.4-0.3-0.4-0.3-0.3
Short access total infusions0.00.00.00.1-0.0-0.1-0.2-0.1-0.10.0-0.2-0.1-0.2-0.1
Short access day 1 locomotion0.10.10.30.3-0.4-0.3-0.6-0.3-0.4-0.4-0.3-0.4-0.3-0.4
Short access day 10 total locomotion0.10.10.10.2-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.3
Short access total locomotion0.60.60.70.7-0.8-0.8-0.7-0.8-0.8-0.8-0.8-0.8-0.7-0.8
Compulsive drug intake1.81.82.0-1.41.31.31.31.31.31.21.41.41.41.4
One hour access (0.3 mA shock)1.11.31.81.0-1.2-1.3-1.3-1.2-1.2-1.2-1.0-1.1-1.0-1.1
One hour access (shock baseline)1.31.51.71.1-1.2-1.3-1.3-1.2-1.2-1.2-1.2-1.2-1.1-1.2
Number of responses in last shaping day3.83.84.5-1.82.02.11.92.02.02.11.81.91.81.9
Context. condit. distance diff. score2.43.03.5-1.81.81.91.61.71.71.71.81.71.81.7
Locomotion velocity, session 10.60.71.10.7-0.9-1.0-1.0-0.8-0.8-0.8-0.7-0.8-0.6-0.8
Locomotion distance, session 10.10.20.2-0.50.40.50.30.40.40.40.40.40.40.4
Locomotion velocity, session 20.10.10.40.3-0.5-0.6-0.4-0.4-0.4-0.4-0.1-0.4-0.2-0.4
Locomotion distance, session 20.00.00.1-0.10.20.30.20.20.20.20.20.20.30.2
Locomotion velocity, session 31.92.22.8-1.41.61.31.61.51.61.71.41.51.21.5
Locomotion distance, session 31.21.31.6-1.31.21.11.21.11.21.20.91.10.91.1
Stereotopy head waving bouts, day 30.91.12.0-1.10.90.70.91.11.00.91.21.01.41.0
Stereotopy head waving duration, day 30.10.10.3-0.20.10.00.10.20.10.10.40.20.60.2
Locomotion velocity, session 70.40.40.6-0.70.70.70.50.70.70.70.50.70.60.7
Locomotion distance, session 70.20.20.6-0.40.50.70.60.40.50.50.30.40.30.4
Stereotopy head waving bouts, day 70.30.30.80.4-0.6-0.9-0.7-0.5-0.6-0.6-0.5-0.5-0.4-0.5
Stereotopy head waving duration, day 70.50.61.00.7-0.8-1.0-0.9-0.8-0.8-0.8-0.7-0.7-0.6-0.7
Locomotion velocity, session 80.10.10.2-0.20.20.20.00.20.20.20.50.20.30.2
Locomotion distance, session 82.94.34.9-2.12.12.21.82.02.12.12.22.12.12.1
Degree of sensitization distance0.10.10.10.3-0.3-0.0-0.3-0.2-0.3-0.4-0.1-0.3-0.1-0.3
Degree of sensitization stereotypy0.40.51.10.6-0.7-1.0-0.8-0.6-0.6-0.7-0.6-0.5-0.6-0.5
Condit. Reinf. active minus inactive responses0.20.20.5-0.60.2-0.20.20.30.30.30.60.40.70.4
Condit. Reinf. active-inactive response ratio0.10.10.3-0.40.20.10.20.20.10.00.40.20.50.1
Condit. Reinf. active responses0.10.10.3-0.40.2-0.20.20.20.20.20.50.30.60.3
Condit. Reinf. inactive responses0.20.20.30.5-0.4-0.3-0.4-0.5-0.4-0.3-0.5-0.4-0.5-0.4
Incentive salience index mean0.40.50.9-0.90.60.10.40.70.60.60.90.71.00.7
Condit. Reinf. lever presses0.10.10.3-0.60.30.00.10.40.40.40.40.50.50.5
Time in familiar zone, hab. session 10.00.00.1-0.40.10.20.00.20.20.20.20.20.20.2
Time in novel zone, hab. session 10.20.20.3-0.30.50.40.50.50.50.50.50.50.50.5
Total zone transitions, hab. session 11.21.62.5-1.51.21.11.11.31.21.11.51.21.61.2
Total locomotion distance, hab. session 10.60.81.1-1.10.90.80.70.90.90.91.00.91.00.9
Locomotion velocity, hab. session 10.10.20.3-0.50.40.30.30.40.40.40.50.40.50.4
Time in familiar zone, hab. session 20.10.10.20.2-0.2-0.0-0.4-0.2-0.2-0.3-0.2-0.2-0.2-0.2
Time in novel zone, hab. session 20.60.60.8-0.70.70.50.90.80.80.80.80.80.80.7
Total zone transitions, hab. session 20.30.40.6-0.60.70.70.50.60.60.60.80.70.80.7
Total locomotion distance, hab. session 20.20.30.4-0.50.60.60.50.50.60.60.60.60.60.6
Locomotion velocity, hab. session 20.40.60.7-0.70.80.80.60.70.80.80.70.80.80.8
Novel to familiar place preference ratio0.10.20.30.4-0.4-0.4-0.2-0.4-0.5-0.6-0.2-0.4-0.2-0.4
Novelty place preference0.00.00.10.2-0.2-0.2-0.1-0.2-0.3-0.4-0.1-0.2-0.1-0.2
Time in novel zone, NPP test0.00.00.00.0-0.1-0.10.1-0.0-0.1-0.20.1-0.10.1-0.1
Total zone transitions, NPP test1.11.61.9-1.31.31.11.11.21.21.31.41.31.31.3
Total locomotion distance, NPP test0.30.40.5-0.60.70.60.50.60.60.70.70.60.60.6
Locomotion velocity, NPP test0.20.30.4-0.50.60.60.40.50.50.60.60.50.40.5
Pavlov. Cond. lever latency0.40.50.60.8-0.7-0.4-0.7-0.7-0.7-0.7-0.6-0.7-0.7-0.7
Pavlov. Cond. magazine entry latency0.20.20.50.3-0.5-0.7-0.4-0.5-0.5-0.5-0.5-0.5-0.4-0.5
Pavlov. Cond. change in total contacts0.10.10.20.2-0.3-0.5-0.1-0.3-0.3-0.4-0.2-0.3-0.1-0.3
Pavlov. Cond. index score0.00.00.0-0.20.1-0.00.10.10.10.00.00.10.10.1
Pavlov. Cond. latency score0.00.00.0-0.10.1-0.10.10.10.10.00.00.10.10.1
Pavlov. Cond. lever contacts0.50.60.7-0.80.80.60.70.80.80.70.80.80.80.8
Pavlov. Cond. magazine entry number0.20.30.4-0.40.50.60.40.50.50.60.50.50.60.5
Pavlov. Cond. intertrial magazine entries0.50.60.70.7-0.8-0.8-0.6-0.7-0.8-0.8-0.7-0.8-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.0-0.1-0.20.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1
Pavlov. Cond. response bias0.20.30.4-0.70.60.40.60.50.50.50.50.60.50.6
Bone: apparent density0.40.71.1-0.80.80.90.60.90.80.80.70.81.10.8
Bone surface0.00.00.10.20.20.1-0.10.20.20.20.30.20.30.2
Bone volume0.20.30.5-0.40.60.60.30.60.60.60.60.60.70.6
Bone: connectivity density0.00.10.3-0.30.20.20.10.20.20.20.30.20.60.2
Bone: cortical apparent density1.51.92.51.4-1.4-1.4-1.3-1.3-1.4-1.6-1.3-1.4-1.1-1.4
Bone: cortical area0.10.10.2-0.20.30.40.00.30.30.20.30.40.50.4
Bone: cortical porosity1.51.61.9-1.31.31.31.11.21.31.31.41.31.41.3
Bone: cortical porosity0.20.30.5-0.60.50.50.30.50.50.40.70.50.70.5
Bone: cortical thickness0.50.91.1-0.81.01.10.71.00.90.90.81.01.01.0
Bone: cortical thickness0.91.01.2-1.01.00.90.91.11.11.11.01.10.91.1
Bone: cortical tissue density1.62.02.61.5-1.5-1.5-1.4-1.3-1.5-1.6-1.3-1.5-1.2-1.4
Bone: elastic displacement1.41.51.8-1.31.21.31.31.21.31.31.21.21.21.2
Bone: elastic work1.52.02.5-1.61.41.51.11.31.31.31.51.41.61.4
Bone: endosteal estimation0.00.10.5-0.10.30.20.00.20.20.20.70.30.40.3
Bone: endosteal perimeter0.40.91.31.1-0.9-0.9-1.1-1.0-1.0-0.9-0.7-0.9-0.8-0.9
Bone: final force0.00.10.2-0.20.30.40.00.30.30.30.10.30.20.3
Bone: final moment0.10.20.4-0.50.50.60.20.50.50.50.40.50.40.5
Bone: marrow area0.10.10.6-0.20.30.30.00.30.20.20.80.30.40.3
Bone: maximum diameter0.30.50.80.8-0.7-0.7-0.9-0.7-0.8-0.8-0.6-0.7-0.5-0.7
Bone: maximum force0.10.20.3-0.50.50.60.20.50.40.40.40.50.50.5
Bone: maximum moment0.30.50.7-0.80.80.90.50.70.70.70.70.80.80.8
Bone: minimum diameter0.81.52.1-0.91.21.20.91.21.21.21.41.31.41.3
Bone: periosteal estimation0.10.20.5-0.20.50.50.10.40.40.40.70.50.60.5
Bone: periosteal perimeter0.20.30.70.7-0.5-0.5-0.8-0.6-0.6-0.6-0.5-0.5-0.5-0.5
Bone: post-yield work0.00.00.10.1-0.1-0.1-0.30.0-0.1-0.10.1-0.00.10.0
Bone: stiffness0.00.00.1-0.20.20.3-0.00.20.20.10.10.20.20.2
Bone: tissue strength0.10.10.10.0-0.2-0.2-0.2-0.2-0.2-0.3-0.3-0.2-0.1-0.2
Bone: trabecular number1.62.53.4-1.61.51.51.31.61.61.51.61.61.91.6
Bone: trabecular spacing0.50.71.00.7-0.8-0.8-0.6-0.8-0.9-0.9-0.9-0.9-1.0-0.9
Bone: trabecular thickness0.30.30.4-0.50.60.60.50.60.60.60.40.60.60.6
Bone: trabecular tissue density2.83.94.31.9-2.0-2.0-1.9-2.0-2.0-2.1-1.8-2.0-2.0-2.0
Breakpoint value in progressive ratio session0.00.00.30.1-0.3-0.2-0.6-0.1-0.2-0.2-0.1-0.1-0.1-0.1
Distance traveled before self-admin3.33.64.1-1.82.02.01.91.81.92.01.81.91.81.9
Distance traveled after self-admin2.83.13.4-1.71.71.71.51.81.81.81.81.81.81.8
Delta time in closed arm before/after self-admin5.15.06.5-2.02.32.42.52.32.22.32.02.22.02.2
Delta time in open arm before/after self-admin2.72.52.91.7-1.6-1.5-1.3-1.6-1.6-1.5-1.7-1.7-1.7-1.7
Diff in mean of infusions in LGA sessions1.31.41.8-1.21.21.31.11.21.21.21.21.11.31.1
Extinction: sum of active levers before priming1.11.11.3-1.01.11.11.11.11.11.11.01.11.01.1
Active lever presses in extinction session 62.92.84.0-1.41.81.92.01.71.71.81.41.61.41.6
Delta distance traveled before/after self-admin0.10.10.2-0.40.10.0-0.20.30.20.20.40.30.40.4
Delta ambulatory time before/after self-admin0.10.20.70.2-0.5-0.5-0.8-0.2-0.3-0.4-0.2-0.2-0.2-0.2
Time in closed arm before self-admin2.93.33.91.8-1.8-1.9-1.4-1.9-1.9-1.8-1.8-2.0-1.8-2.0
Time in closed arm after self-admin0.10.10.20.3-0.3-0.3-0.0-0.3-0.4-0.4-0.3-0.4-0.3-0.4
Time in open arm before self-admin1.11.21.4-1.11.01.10.71.11.11.11.11.21.11.2
Time in open arm after self-admin0.10.10.2-0.20.40.40.30.40.40.50.20.30.20.3
Sum of active levers in priming session hrs 5-60.40.40.8-0.40.70.70.90.60.60.80.40.50.40.5
Time to tail flick, vehicle, before self-admin0.70.72.5-0.60.90.91.60.70.70.80.60.70.60.6
Time to tail flick, vehicle, after self-admin0.50.50.6-0.70.80.70.60.70.70.80.60.70.70.7
Time to tail flick, test, before self-admin0.20.20.3-0.40.40.30.50.40.40.50.40.40.40.4
Time to tail flick, test, after self-admin2.62.73.1-1.71.61.51.21.71.61.61.71.71.71.7
Delta time to tail flick, vehicle, before/after SA0.00.00.3-0.00.0-0.0-0.50.00.00.00.00.10.00.1
Delta time to tail flick, test, before/after SA0.20.20.2-0.50.30.40.10.40.40.30.50.40.40.4
Ambulatory time before self-admin6.26.56.8-2.62.62.52.42.52.62.52.62.62.62.6
Ambulatory time after self-admin2.93.23.8-1.91.71.61.41.81.81.72.01.91.91.9
Total heroin consumption1.41.62.11.2-1.4-1.5-1.5-1.2-1.3-1.2-1.2-1.3-1.2-1.3
Area under the delay curve0.80.81.00.9-0.9-0.8-1.0-0.9-0.9-1.0-0.9-0.9-0.9-0.9
Delay disc. indifference point, 0s delay0.00.00.10.10.10.30.1-0.1-0.1-0.1-0.2-0.2-0.1-0.2
Delay disc. indifference point, 16s delay0.10.10.10.3-0.2-0.00.3-0.2-0.2-0.1-0.4-0.2-0.4-0.2
Delay disc. indifference point, 2s delay0.10.10.40.1-0.3-0.3-0.7-0.3-0.3-0.4-0.2-0.3-0.2-0.3
Delay disc. indifference point, 24s delay3.73.64.01.8-2.0-1.9-2.0-1.8-1.9-2.0-1.8-1.8-1.8-1.8
Delay disc. indifference point, 4s delay0.10.10.10.30.00.10.0-0.2-0.2-0.1-0.4-0.3-0.4-0.3
Delay disc. indifference point, 8s delay0.70.71.30.7-0.8-0.7-1.1-0.8-0.8-0.9-0.7-0.8-0.7-0.8
Delay discount exponential model param0.70.71.1-0.80.90.81.10.80.90.90.80.80.80.8
Delay discount hyperbolic model param0.70.71.1-0.80.80.71.00.80.80.90.80.80.80.8
Fecal boli incidents, locomotor time 10.20.20.4-0.50.40.50.60.40.50.40.60.40.60.4
Change in fecal boli incidents, locomotor task0.40.31.00.6-0.5-0.5-1.0-0.5-0.5-0.6-0.5-0.5-0.6-0.5
Time >=10cm from walls, locomotor time 10.40.40.9-0.90.30.3-0.10.60.50.21.00.70.90.7
Bouts of movement, locomotor time 10.00.00.1-0.30.00.2-0.10.20.20.00.30.30.30.3
Total resting periods, locomotor time 10.10.10.2-0.40.00.2-0.10.30.20.00.40.30.40.3
Rest time, locomotor task time 10.30.40.5-0.70.50.60.60.60.60.40.70.60.60.6
Distance moved, locomotor task time 10.50.61.40.9-0.5-0.5-1.2-0.7-0.6-0.5-0.8-0.7-0.8-0.7
Vertical activity count, locomotor time 10.10.10.30.50.0-0.1-0.2-0.3-0.20.0-0.5-0.3-0.4-0.3
Time >=10cm from walls, locomotor time 21.01.11.5-1.11.01.00.51.11.00.81.21.11.11.1
Bouts of movement, locomotor time 20.10.10.3-0.5-0.2-0.1-0.10.20.2-0.10.40.30.30.3
Total resting periods, locomotor time 20.10.10.2-0.3-0.4-0.4-0.3-0.0-0.1-0.30.20.00.10.1
Rest time, locomotor task time 20.30.40.50.6-0.7-0.6-0.6-0.6-0.6-0.7-0.5-0.6-0.6-0.6
Distance moved, locomotor task time 20.00.00.20.00.30.4-0.00.20.20.3-0.00.10.00.1
Vertical activity count, locomotor time 21.61.82.5-1.11.61.51.51.21.31.51.11.21.21.2
Weight adjusted by age0.10.20.60.5-0.4-0.4-0.4-0.2-0.5-0.80.0-0.2-0.0-0.2
Seeking ratio, delayed vs. immediate footshock3.74.25.5-2.31.91.90.82.12.01.92.32.22.32.2
Locomotion in novel chamber0.80.91.1-0.91.01.00.90.90.90.91.11.01.11.0
Locomotion in novel chamber post-restriction1.51.82.3-1.51.31.21.41.31.31.31.41.31.41.3
Progressive ratio1.01.11.61.1-1.1-1.1-1.3-1.0-1.0-0.9-1.1-1.0-1.1-1.0
Food seeking constrained by brief footshock0.20.20.50.5-0.1-0.10.5-0.5-0.3-0.1-0.7-0.5-0.7-0.6
Seeking ratio, punishment vs. effort0.20.30.8-0.50.60.50.90.40.40.50.40.40.40.4
Run reversals in cocaine runway, females0.40.41.80.3-0.7-0.7-1.3-0.5-0.6-0.7-0.3-0.4-0.3-0.4
Run reversals in cocaine runway, males0.60.60.9-0.90.70.70.50.80.70.50.90.81.00.8
Latency to leave start box in cocaine runway0.10.10.1-0.30.30.30.20.30.30.40.30.30.30.3
Latency to leave start box in cocaine runway, F0.10.10.3-0.10.40.40.40.30.40.50.10.30.10.3
Latency to leave start box in cocaine runway, M0.10.10.1-0.40.10.1-0.20.20.20.10.40.30.40.3
Cd content in liver0.10.20.3-0.30.40.50.40.30.40.40.40.40.40.4
Co content in liver1.11.31.7-1.31.10.91.21.21.11.11.11.11.11.1
Cu content in liver0.10.10.5-0.40.30.30.40.40.20.10.50.30.70.3
Fe content in liver2.12.53.0-1.51.61.71.61.61.61.51.61.61.71.6
K content in liver0.50.50.70.6-0.7-0.8-0.8-0.7-0.7-0.6-0.7-0.7-0.7-0.7
Mg content in liver4.14.24.42.0-2.1-2.1-2.0-2.1-2.1-2.1-2.0-2.1-1.9-2.1
Mn content in liver0.00.00.10.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2
Na content in liver0.10.10.3-0.40.10.10.20.10.10.00.50.10.50.1
Rb content in liver0.20.20.4-0.70.40.40.30.40.40.40.40.40.60.4
Se content in liver1.92.32.7-1.51.51.61.61.51.51.51.51.51.41.5
Sr content in liver0.10.10.10.2-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.3-0.2-0.3
Zn content in liver2.32.63.11.7-1.6-1.6-1.6-1.6-1.7-1.8-1.4-1.6-1.3-1.6