Hub : Genes

Tamm41

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007874 0.28 0.13 0.0e+00 0.23 0.26 0.27 0.26 9.6e-25 2.3e-29 1.8e-29 4.0e-29
2 Adipose mRNA stability ENSRNOG00000007874 0.19 0.11 0.0e+00 0.17 0.16 0.16 0.17 2.5e-18 1.0e-17 1.6e-17 3.7e-18
3 BLA gene expression ENSRNOG00000007874 0.13 0.09 3.6e-06 0.04 0.09 0.08 0.08 3.3e-03 9.5e-06 4.2e-05 5.1e-05
4 Brain gene expression ENSRNOG00000007874 0.11 0.06 4.0e-08 0.1 0.1 0.09 0.09 2.9e-09 2.7e-09 4.5e-09 5.3e-09
5 Brain intron excision ratio chr4:148078695:148082216 0.04 0.03 6.8e-03 0.01 0.01 0 0.01 4.5e-02 2.5e-02 1.9e-01 3.9e-02
6 IL gene expression ENSRNOG00000007874 0.2 0.13 3.1e-03 0.07 0.08 0.06 0.07 7.2e-03 7.1e-03 1.3e-02 8.4e-03
7 LHb gene expression ENSRNOG00000007874 0.31 0.16 2.3e-04 0.08 0.13 0.09 0.11 7.1e-03 5.2e-04 3.7e-03 1.6e-03
8 Liver gene expression ENSRNOG00000007874 0.23 0.13 0.0e+00 0.13 0.17 0.18 0.18 1.7e-14 1.0e-18 2.5e-19 3.5e-19
9 Liver mRNA stability ENSRNOG00000007874 0.04 0.03 5.9e-04 0.03 0.02 0.03 0.02 2.8e-04 1.6e-03 8.1e-04 1.0e-03
10 NAcc gene expression ENSRNOG00000007874 0.13 0.08 4.9e-07 0.05 0.08 0.07 0.07 1.1e-04 1.1e-06 1.0e-05 5.6e-06
11 PL gene expression ENSRNOG00000007874 0.06 0.04 3.0e-03 0 0.02 0 0.01 1.7e-01 1.8e-02 1.5e-01 1.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.34.25.22.12.21.62.21.72.22.11.82.32.12.0
BMI without tail0.71.43.31.81.2-0.51.0-0.31.01.41.21.11.31.6
Body weight0.52.23.31.71.50.61.40.71.41.61.81.81.51.5
Epididymis fat weight0.20.50.8-0.8-0.7-0.3-0.7-0.3-0.7-0.8-0.6-0.5-0.8-0.9
Glucose1.32.02.71.11.61.61.51.71.51.31.21.61.31.1
Heart weight1.52.12.91.11.41.71.71.71.71.40.81.31.61.3
Left kidney weight0.92.76.3-0.7-1.8-2.5-1.8-2.5-1.7-1.2-0.8-1.6-1.4-0.8
Right kidney weight2.05.69.8-1.4-2.6-3.1-2.6-3.1-2.6-2.1-1.5-2.1-2.3-1.7
Tail length0.41.14.40.1-0.8-2.1-1.0-2.0-1.0-0.5-0.1-0.7-0.7-0.2
Length with tail0.20.92.9-0.1-0.9-1.7-1.0-1.6-1.0-0.60.2-0.5-0.7-0.4
Length without tail0.40.81.3-1.0-1.1-0.6-1.0-0.6-1.0-1.0-0.3-0.7-1.1-1.1
Liver weight, left0.71.11.5-0.8-1.2-1.0-1.2-1.0-1.2-1.1-1.1-1.0-1.1-1.0
Liver weight, right1.32.23.9-0.8-1.6-2.0-1.6-2.0-1.6-1.3-1.0-1.4-1.4-1.1
Parametrial fat weight0.10.10.4-0.3-0.00.70.00.60.0-0.2-0.10.2-0.2-0.4
Retroperitoneal fat weight0.30.81.9-1.3-0.90.2-0.90.1-0.9-1.1-0.8-0.4-1.1-1.4
Intraocular pressure0.00.00.10.10.1-0.10.0-0.00.00.10.30.20.10.1
Extensor digitorum longus weight7.530.134.65.45.64.05.94.45.95.85.85.75.95.5
Soleus weight1.44.04.71.82.11.82.21.92.22.02.12.22.01.8
Tibialis anterior weight0.41.34.9-0.20.92.21.02.11.00.40.41.10.5-0.0
Tibia length0.82.33.0-1.5-1.6-1.3-1.7-1.4-1.7-1.7-1.1-1.4-1.7-1.6
Number of licking bursts0.20.20.7-0.1-0.5-0.8-0.5-0.8-0.5-0.3-0.1-0.6-0.3-0.1
Food consumed during 24 hour testing period0.00.10.2-0.3-0.20.1-0.20.0-0.2-0.3-0.3-0.0-0.3-0.4
Times rat made contact with spout0.10.10.50.1-0.3-0.7-0.3-0.7-0.3-0.10.1-0.3-0.20.0
Mean time between licks in bursts0.30.41.00.70.50.00.50.10.50.71.00.70.60.7
Mean num. licks in bursts0.00.00.0-0.0-0.00.10.00.10.0-0.0-0.10.1-0.1-0.1
Std. dev. time between licks in bursts0.30.41.20.8-0.1-1.1-0.0-1.0-0.00.40.80.00.30.7
Water consumed over 24 hours0.00.10.20.40.1-0.20.2-0.10.20.30.20.20.20.3
Indifference point 0 sec0.00.10.3-0.10.10.60.10.50.1-0.1-0.30.1-0.0-0.1
Indifference point AUC1.01.22.2-1.0-1.0-0.7-1.1-0.8-1.1-1.1-1.5-1.3-1.1-1.1
Indifference point function ln k1.72.53.41.71.40.71.60.81.61.81.81.61.81.8
Indifference point function log k1.72.53.41.71.40.71.60.81.61.81.81.61.81.8
Delay discounting total patch changes 0 sec0.10.20.50.20.40.70.50.70.50.3-0.00.30.30.2
Delay discounting total patch changes 12 sec0.60.81.5-0.9-0.8-0.4-0.9-0.5-0.9-1.0-1.2-1.0-0.9-0.9
Delay discounting total patch changes 18 sec0.91.22.6-1.3-1.0-0.1-1.0-0.3-1.0-1.2-1.6-1.2-1.2-1.3
Delay discounting total patch changes 24 sec0.30.41.2-0.60.31.10.01.00.0-0.4-0.9-0.0-0.3-0.6
Delay discounting total patch changes 6 sec0.30.50.80.60.70.90.80.90.80.60.30.70.60.5
Delay discounting time to switch 0 sec0.30.50.80.50.70.70.70.70.70.60.90.80.60.5
Delay discounting water rate 0 sec0.00.10.2-0.0-0.1-0.4-0.3-0.4-0.3-0.2-0.3-0.2-0.2-0.1
Delay discounting water rate 12 sec0.00.10.20.30.2-0.30.1-0.20.20.30.20.20.30.4
Delay discounting water rate 18 sec0.40.50.70.60.80.80.80.80.80.70.50.80.70.6
Delay discounting water rate 24 sec0.10.10.30.0-0.2-0.6-0.2-0.5-0.2-0.00.0-0.3-0.10.1
Delay discounting water rate 6 sec0.10.10.50.1-0.2-0.7-0.3-0.7-0.3-0.10.2-0.1-0.20.0
Locomotor activity1.22.02.5-1.1-1.6-1.5-1.5-1.6-1.6-1.4-0.9-1.4-1.5-1.2
Locomotor testing distance1.72.83.5-1.3-1.9-1.8-1.9-1.8-1.9-1.7-1.0-1.6-1.8-1.5
Locomotor testing rearing3.55.47.6-2.7-2.4-0.9-2.4-1.2-2.4-2.7-2.4-2.2-2.7-2.8
Light reinforcement 10.71.31.6-1.0-1.2-1.1-1.2-1.1-1.2-1.1-1.2-1.2-1.2-1.0
Light reinforcement 20.10.10.2-0.3-0.10.4-0.10.3-0.1-0.3-0.10.3-0.3-0.5
Reaction time number correct0.50.71.30.50.81.11.01.11.00.80.60.80.80.6
Reaction time mean minus median0.20.30.7-0.8-0.50.3-0.40.2-0.4-0.7-0.5-0.4-0.6-0.8
Reaction time mean minus median AUC0.20.30.6-0.8-0.50.3-0.40.2-0.4-0.7-0.6-0.4-0.6-0.8
Reaction time num false alarms2.02.84.92.21.5-0.01.60.21.62.02.11.51.92.2
Reaction time num false alarms AUC1.31.93.71.91.1-0.51.1-0.21.11.61.91.21.51.8
Reaction time trials correct on left0.50.71.30.50.81.11.01.11.00.80.60.80.80.6
Reaction time trials on left0.40.61.00.40.71.00.91.00.90.70.60.70.80.6
Reaction time mean1.41.93.4-1.8-1.10.1-1.3-0.1-1.3-1.7-1.6-1.2-1.6-1.8
Reaction time mean AUC1.31.73.1-1.7-1.10.0-1.3-0.1-1.3-1.6-1.5-1.1-1.5-1.8
Median of all reaction times1.31.83.4-1.8-1.00.2-1.20.0-1.2-1.6-1.6-1.1-1.5-1.8
Reaction time omissions0.81.12.6-0.5-1.0-1.6-1.2-1.6-1.1-0.8-0.3-1.0-0.9-0.6
Reaction time false alarm rate0.50.71.41.20.3-1.00.3-0.90.30.81.10.30.71.1
Reaction time premature initiation rate0.50.71.9-0.7-0.6-0.6-0.8-0.6-0.8-0.8-1.4-1.2-0.7-0.6
Reaction time premature initiations0.30.41.3-0.6-0.4-0.2-0.5-0.3-0.5-0.6-1.1-1.0-0.5-0.5
Std. dev. reaction times0.71.01.3-1.0-1.0-0.7-1.1-0.8-1.1-1.1-0.7-0.9-1.1-1.1
Reaction time trials completed0.40.61.00.40.71.00.91.00.90.70.60.70.80.6
Reaction time trials AUC0.50.71.10.50.81.01.01.11.00.80.70.80.80.7
Social response proportion2.93.25.5-2.1-1.8-0.7-1.7-0.9-1.7-1.9-2.3-2.1-1.8-1.8
Social responses1.41.93.0-1.0-1.3-1.7-1.5-1.7-1.5-1.2-1.0-1.5-1.3-1.0
Social time0.30.40.6-0.4-0.6-0.8-0.7-0.8-0.7-0.6-0.2-0.7-0.6-0.5
Conditioned locomotion0.30.41.4-0.10.61.20.51.10.50.2-0.20.30.30.0
Cocaine response after cond. corrected2.93.37.4-0.8-1.9-2.7-2.0-2.7-2.0-1.4-0.8-1.8-1.6-1.0
Cocaine response after cond. not corrected5.46.08.3-1.8-2.6-2.8-2.7-2.9-2.7-2.3-1.9-2.6-2.4-1.9
Cocaine response before conditioning0.91.12.6-1.4-0.80.2-0.90.0-0.9-1.2-1.6-1.0-1.1-1.3
Saline control response4.35.79.4-3.0-2.2-0.1-2.3-0.4-2.3-2.8-2.9-2.2-2.7-3.1
Condit. Reinf. active minus inactive responses1.72.12.7-1.3-1.7-1.3-1.6-1.4-1.6-1.5-1.1-1.3-1.6-1.4
Condit. Reinf. active-inactive response ratio0.30.30.9-0.1-0.6-0.9-0.5-0.9-0.5-0.30.1-0.3-0.4-0.2
Condit. Reinf. active responses1.21.72.2-1.4-1.4-0.8-1.4-0.9-1.4-1.5-1.3-1.2-1.5-1.5
Condit. Reinf. inactive responses1.11.32.6-1.5-1.00.3-1.00.1-1.0-1.4-1.6-0.9-1.3-1.5
Condit. Reinf. lever presses0.30.40.9-0.3-0.6-0.9-0.7-0.9-0.7-0.5-0.2-0.5-0.6-0.4
Condit. Reinf. lever reinforcers received2.02.83.5-1.7-1.8-1.2-1.8-1.3-1.8-1.8-1.6-1.6-1.9-1.8
Pavlov. Cond. lever latency0.10.10.10.20.30.30.30.30.40.30.30.30.30.3
Pavlov. Cond. magazine entry latency0.20.20.90.2-0.4-0.9-0.4-0.9-0.4-0.10.2-0.2-0.2-0.0
Pavlov. Cond. change in total contacts1.01.33.5-0.4-1.2-1.9-1.3-1.8-1.3-0.8-0.3-1.1-1.0-0.6
Pavlov. Cond. index score0.20.30.8-0.1-0.5-0.9-0.6-0.9-0.6-0.4-0.0-0.4-0.5-0.3
Pavlov. Cond. latency score0.20.21.00.2-0.3-1.0-0.4-0.9-0.4-0.10.2-0.3-0.2-0.0
Pavlov. Cond. lever contacts0.10.10.50.1-0.2-0.7-0.3-0.6-0.3-0.10.1-0.2-0.10.0
Pavlov. Cond. magazine entry number0.81.02.80.21.01.71.11.61.10.70.10.70.80.5
Pavlov. Cond. intertrial magazine entries0.40.51.2-1.1-0.40.5-0.50.4-0.5-0.8-0.9-0.6-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.1-0.5-1.0-0.6-0.9-0.6-0.4-0.0-0.4-0.5-0.3
Pavlov. Cond. response bias0.10.20.70.1-0.3-0.8-0.4-0.8-0.4-0.10.3-0.1-0.2-0.1
Conditioned reinforcement - actives2.01.95.20.61.12.31.52.31.51.10.41.21.10.7
Conditioned reinforcement - inactives0.30.30.4-0.4-0.5-0.6-0.6-0.6-0.6-0.5-0.4-0.4-0.6-0.6
Conditioned locomotion0.00.10.2-0.4-0.20.40.00.40.0-0.1-0.1-0.1-0.1-0.2
Intermittent access intake day 1-15 change3.33.34.11.91.91.52.01.62.02.01.41.82.01.8
Intermittent access intake escalation2.72.73.41.61.71.61.81.71.81.70.91.71.71.5
Intermittent access intake escalation 24.64.66.32.52.21.12.31.42.32.41.92.22.42.4
Intermitt. access day 1 inactive lever presses1.41.54.2-0.4-1.0-2.0-1.3-2.0-1.3-0.9-0.4-1.2-1.0-0.6
Intermitt. access day 15 inactive lever presses0.60.61.3-0.4-0.7-1.1-0.9-1.1-0.9-0.7-0.4-0.6-0.8-0.6
Intermitt. access escalation Index0.10.10.20.40.30.00.20.00.20.3-0.00.30.30.3
Intermittent access day 1 total infusions0.10.10.5-0.2-0.10.70.20.70.2-0.0-0.4-0.00.1-0.1
Intermittent access day 15 total infusions2.73.16.71.11.52.62.02.62.01.50.31.61.61.1
Intermittent access terminal intake (last 3 days)4.34.77.11.72.02.62.52.72.52.11.12.02.21.8
Intermittent access total infusions1.11.23.80.40.71.91.21.91.30.8-0.10.80.90.5
Intermittent access day 1 locomotion1.01.01.50.80.91.21.21.21.21.00.50.91.10.9
Intermittent access day 15 total locomotion3.03.24.51.51.72.02.12.12.11.80.71.71.91.7
Intermittent access total locomotion1.92.14.00.91.32.01.72.01.71.30.51.31.41.1
Intermittent access standard deviation0.00.00.00.20.00.10.10.10.10.10.10.20.00.0
Cocaine induced anxiety0.00.00.1-0.20.1-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.1
Post-drug Anxiety2.72.94.1-1.5-1.7-2.0-1.9-2.0-1.9-1.6-1.0-1.7-1.7-1.4
Baseline Anxiety3.43.65.2-1.5-2.2-2.2-2.2-2.3-2.1-1.8-0.9-1.9-1.9-1.5
Lifetime Intake0.91.03.40.20.61.91.01.81.00.6-0.20.70.70.3
Incentive Sensitization - Responses1.71.73.20.91.21.81.51.81.51.10.31.21.20.9
Incentive Sensitization - Breakpoint2.12.13.71.11.41.91.71.91.71.30.41.41.41.1
Progressive ratio test 1 active lever presses0.20.20.4-0.6-0.50.5-0.20.4-0.2-0.4-0.5-0.3-0.4-0.6
Progressive ratio test 1 breakpoint0.10.10.3-0.3-0.20.50.10.50.1-0.1-0.2-0.0-0.1-0.3
Progressive ratio test 1 inactive lever presses0.40.41.3-0.2-0.6-1.1-0.7-1.1-0.7-0.40.1-0.5-0.6-0.4
Progressive ratio test 2 active lever presses1.71.85.10.61.02.21.52.21.51.00.11.11.20.7
Progressive ratio test 2 breakpoint1.51.74.60.61.02.11.52.11.51.00.11.11.10.7
Progressive ratio test 2 inactive lever presses0.00.00.10.10.10.30.10.30.10.0-0.20.3-0.0-0.1
Total sessions with >9 infusions2.12.33.9-1.9-1.6-0.1-1.4-0.2-1.4-1.8-1.8-1.4-1.7-2.0
Short access day 1 total inactive lever presses1.51.62.2-1.4-1.4-0.8-1.4-0.9-1.4-1.4-1.1-1.2-1.5-1.5
Short access day 10 total inactive lever presses2.12.37.6-0.3-1.1-2.8-1.6-2.7-1.6-0.90.0-1.3-1.1-0.5
Short access day 1 total infusions0.20.20.4-0.5-0.40.4-0.20.4-0.2-0.4-0.4-0.2-0.4-0.7
Short access day 10 total infusions0.60.61.70.40.51.30.91.30.90.60.00.60.70.4
Short access total infusions0.30.31.1-0.7-0.31.00.00.90.0-0.4-0.8-0.2-0.3-0.6
Short access day 1 locomotion1.21.31.70.91.01.21.31.31.31.21.21.11.21.0
Short access day 10 total locomotion0.00.00.10.0-0.1-0.3-0.1-0.3-0.10.0-0.2-0.2-0.00.1
Short access total locomotion0.30.30.9-0.7-0.20.90.00.80.0-0.3-0.8-0.3-0.3-0.6
Compulsive drug intake0.40.41.9-0.60.00.8-0.20.6-0.2-0.5-1.4-0.3-0.4-0.7
One hour access (0.3 mA shock)2.52.99.20.61.33.01.83.01.81.1-0.21.31.30.6
One hour access (shock baseline)2.42.86.11.01.32.51.92.52.01.50.71.41.61.2
Number of responses in last shaping day3.33.44.21.61.61.82.01.92.01.92.11.71.91.6
Context. condit. distance diff. score3.64.45.32.22.21.22.21.42.22.32.22.22.32.2
Locomotion velocity, session 10.00.00.10.1-0.0-0.3-0.0-0.3-0.00.1-0.1-0.30.10.2
Locomotion distance, session 10.30.41.3-0.1-0.6-1.1-0.6-1.1-0.6-0.3-0.2-0.6-0.4-0.1
Locomotion velocity, session 20.91.11.4-0.9-1.2-1.1-1.1-1.1-1.1-1.0-0.9-1.1-1.0-0.9
Locomotion distance, session 20.81.23.3-0.3-1.1-1.8-1.1-1.8-1.1-0.7-0.5-1.2-0.8-0.3
Locomotion velocity, session 30.91.02.0-1.3-0.9-0.0-1.0-0.1-1.0-1.2-1.2-0.7-1.2-1.4
Locomotion distance, session 31.01.11.8-1.2-1.1-0.5-1.1-0.6-1.2-1.3-1.0-0.8-1.3-1.3
Stereotopy head waving bouts, day 30.30.41.3-0.1-0.6-1.1-0.6-1.1-0.6-0.3-0.2-0.8-0.4-0.0
Stereotopy head waving duration, day 30.10.20.70.3-0.2-0.8-0.2-0.8-0.20.1-0.0-0.50.10.3
Locomotion velocity, session 70.91.01.6-1.2-1.0-0.4-1.1-0.5-1.1-1.2-0.8-0.8-1.2-1.3
Locomotion distance, session 70.10.10.3-0.4-0.10.6-0.10.5-0.1-0.30.10.3-0.3-0.6
Stereotopy head waving bouts, day 71.41.61.9-1.1-1.3-1.1-1.3-1.2-1.3-1.2-1.3-1.4-1.3-1.1
Stereotopy head waving duration, day 71.41.72.6-0.9-1.4-1.6-1.4-1.6-1.4-1.1-1.1-1.4-1.2-0.9
Locomotion velocity, session 80.30.40.90.90.3-0.90.3-0.70.30.70.70.30.50.9
Locomotion distance, session 81.52.34.12.01.4-0.11.40.11.41.81.81.41.72.0
Degree of sensitization distance0.40.40.50.50.60.60.70.60.70.60.70.60.60.6
Degree of sensitization stereotypy0.40.50.8-0.6-0.7-0.5-0.7-0.6-0.7-0.7-0.9-0.7-0.7-0.6
Condit. Reinf. active minus inactive responses4.14.66.6-2.5-2.1-0.9-2.2-1.1-2.3-2.5-2.2-2.0-2.4-2.6
Condit. Reinf. active-inactive response ratio5.45.87.2-2.6-2.4-1.3-2.5-1.5-2.5-2.7-2.6-2.5-2.7-2.7
Condit. Reinf. active responses1.31.52.9-1.7-1.00.1-1.2-0.1-1.2-1.5-1.4-1.1-1.4-1.7
Condit. Reinf. inactive responses0.60.70.90.60.90.90.91.00.90.70.70.80.80.6
Incentive salience index mean3.34.05.1-2.1-2.0-1.3-2.2-1.4-2.2-2.2-1.9-1.9-2.3-2.2
Condit. Reinf. lever presses0.81.01.7-0.7-1.1-1.3-1.1-1.3-1.1-0.9-0.7-1.0-1.0-0.8
Time in familiar zone, hab. session 10.10.10.2-0.1-0.3-0.4-0.4-0.4-0.4-0.30.0-0.1-0.3-0.3
Time in novel zone, hab. session 10.00.00.0-0.00.10.20.10.20.20.1-0.2-0.10.10.1
Total zone transitions, hab. session 10.70.91.2-1.0-1.1-0.6-1.0-0.7-1.0-1.1-1.1-0.9-1.1-1.0
Total locomotion distance, hab. session 10.10.10.2-0.4-0.20.1-0.20.1-0.2-0.4-0.3-0.1-0.3-0.4
Locomotion velocity, hab. session 10.10.10.2-0.4-0.3-0.1-0.3-0.1-0.3-0.4-0.4-0.3-0.4-0.4
Time in familiar zone, hab. session 20.00.00.10.10.0-0.20.0-0.20.00.10.1-0.20.10.2
Time in novel zone, hab. session 20.00.00.1-0.2-0.2-0.0-0.2-0.0-0.2-0.2-0.2-0.0-0.3-0.3
Total zone transitions, hab. session 21.21.52.7-0.8-1.4-1.6-1.4-1.6-1.4-1.1-0.8-1.2-1.2-0.9
Total locomotion distance, hab. session 21.52.03.0-1.0-1.6-1.7-1.6-1.7-1.6-1.3-0.9-1.4-1.4-1.1
Locomotion velocity, hab. session 21.41.82.6-1.0-1.5-1.6-1.5-1.6-1.5-1.3-0.9-1.3-1.4-1.1
Novel to familiar place preference ratio0.00.00.10.10.20.20.20.20.20.1-0.20.10.20.2
Novelty place preference0.10.10.20.50.50.10.40.10.40.40.20.30.40.5
Time in novel zone, NPP test0.20.20.40.40.60.40.50.40.50.50.10.40.50.5
Total zone transitions, NPP test0.50.72.0-0.2-0.9-1.4-0.8-1.4-0.8-0.5-0.3-0.8-0.6-0.2
Total locomotion distance, NPP test0.10.10.40.3-0.2-0.6-0.1-0.5-0.10.10.3-0.00.00.2
Locomotion velocity, NPP test0.20.21.00.2-0.4-1.0-0.4-1.0-0.4-0.10.3-0.2-0.20.1
Pavlov. Cond. lever latency0.20.30.70.70.4-0.20.5-0.10.50.70.40.10.70.8
Pavlov. Cond. magazine entry latency0.91.12.3-0.6-1.2-1.5-1.2-1.5-1.2-0.9-0.3-0.9-1.0-0.8
Pavlov. Cond. change in total contacts0.10.20.3-0.4-0.4-0.2-0.4-0.2-0.5-0.5-0.2-0.1-0.5-0.6
Pavlov. Cond. index score0.30.30.5-0.5-0.6-0.5-0.7-0.5-0.7-0.7-0.3-0.3-0.7-0.7
Pavlov. Cond. latency score0.30.40.6-0.6-0.7-0.6-0.7-0.6-0.7-0.7-0.3-0.4-0.8-0.7
Pavlov. Cond. lever contacts0.10.10.4-0.5-0.20.2-0.30.2-0.3-0.5-0.5-0.1-0.5-0.6
Pavlov. Cond. magazine entry number0.81.01.40.71.11.21.21.21.21.00.50.81.10.9
Pavlov. Cond. intertrial magazine entries0.20.31.1-0.30.31.10.31.00.3-0.10.10.40.0-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.6-0.5-0.7-0.6-0.7-0.6-0.7-0.7-0.3-0.3-0.8-0.7
Pavlov. Cond. response bias0.70.81.1-0.7-1.0-1.0-1.0-1.0-1.1-0.9-0.5-0.7-1.0-0.9
Bone: apparent density0.20.41.0-0.8-0.7-0.2-0.7-0.2-0.7-0.8-0.3-0.1-0.8-1.0
Bone surface0.61.01.7-1.0-1.1-0.6-1.1-0.7-1.1-1.2-0.6-0.5-1.3-1.3
Bone volume0.20.30.6-0.5-0.5-0.3-0.6-0.3-0.6-0.6-0.10.0-0.7-0.8
Bone: connectivity density0.20.30.4-0.3-0.6-0.6-0.6-0.5-0.6-0.50.10.0-0.6-0.6
Bone: cortical apparent density0.00.10.1-0.2-0.2-0.3-0.3-0.3-0.3-0.2-0.1-0.3-0.2-0.2
Bone: cortical area0.00.00.10.10.30.20.20.20.20.2-0.2-0.10.20.3
Bone: cortical porosity0.10.10.30.2-0.1-0.4-0.0-0.3-0.00.10.60.10.10.2
Bone: cortical porosity0.10.10.60.50.2-0.10.2-0.10.30.40.80.40.30.4
Bone: cortical thickness0.00.00.10.10.30.10.20.10.20.20.0-0.00.20.2
Bone: cortical thickness0.20.20.5-0.7-0.20.4-0.30.3-0.3-0.5-0.7-0.4-0.5-0.7
Bone: cortical tissue density0.00.00.1-0.1-0.1-0.3-0.2-0.3-0.2-0.2-0.0-0.2-0.2-0.1
Bone: elastic displacement0.40.41.2-1.0-0.11.1-0.10.9-0.1-0.6-0.7-0.0-0.5-0.9
Bone: elastic work0.20.20.50.20.50.70.50.70.50.30.30.60.40.2
Bone: endosteal estimation0.10.20.30.30.40.60.50.60.50.40.10.50.40.3
Bone: endosteal perimeter0.20.31.1-0.7-0.40.1-0.5-0.0-0.5-0.6-1.0-0.6-0.6-0.7
Bone: final force0.61.01.31.01.10.81.10.91.11.10.91.11.11.0
Bone: final moment0.71.11.40.91.21.01.21.11.11.10.91.11.10.9
Bone: marrow area0.10.10.30.20.40.50.40.50.40.30.00.40.30.2
Bone: maximum diameter0.30.51.1-0.5-0.6-0.8-0.7-0.8-0.7-0.6-0.9-1.1-0.5-0.3
Bone: maximum force1.11.82.41.21.51.21.51.31.51.41.21.41.41.2
Bone: maximum moment1.01.82.31.11.51.41.51.41.41.31.11.41.31.1
Bone: minimum diameter1.12.02.61.21.61.41.61.51.61.40.91.31.51.4
Bone: periosteal estimation0.10.10.20.20.40.50.40.50.40.3-0.10.20.40.3
Bone: periosteal perimeter0.50.81.9-1.0-0.7-0.3-0.8-0.4-0.8-1.0-1.4-1.1-0.9-0.9
Bone: post-yield work0.00.00.10.30.1-0.30.0-0.30.00.20.1-0.00.10.2
Bone: stiffness0.71.11.41.21.10.51.10.61.11.21.21.01.21.2
Bone: tissue strength0.90.81.1-0.9-0.9-0.6-1.0-0.7-1.0-1.0-0.8-0.8-1.0-1.0
Bone: trabecular number0.91.42.7-1.4-1.2-0.4-1.3-0.4-1.3-1.4-1.0-0.8-1.5-1.6
Bone: trabecular spacing0.50.60.90.70.80.60.90.60.90.90.50.50.91.0
Bone: trabecular thickness0.20.20.7-0.6-0.20.3-0.30.3-0.3-0.6-0.10.2-0.6-0.8
Bone: trabecular tissue density2.43.46.0-2.4-1.60.0-1.7-0.2-1.7-2.2-2.4-1.9-2.0-2.3
Breakpoint value in progressive ratio session3.64.15.02.21.91.42.21.62.22.21.92.22.22.1
Distance traveled before self-admin2.62.84.0-1.5-1.8-1.6-1.8-1.7-1.8-1.7-1.3-2.0-1.7-1.4
Distance traveled after self-admin0.70.81.4-1.1-0.60.0-0.8-0.1-0.8-1.0-1.2-1.0-1.0-1.1
Delta time in closed arm before/after self-admin0.10.10.30.40.1-0.30.1-0.20.10.30.50.10.30.4
Delta time in open arm before/after self-admin0.20.10.40.40.20.00.40.10.40.5-0.1-0.10.50.7
Diff in mean of infusions in LGA sessions0.10.20.6-0.3-0.10.80.10.70.1-0.1-0.60.0-0.1-0.3
Extinction: sum of active levers before priming0.00.00.10.00.10.40.10.30.1-0.1-0.10.3-0.1-0.2
Active lever presses in extinction session 64.24.04.92.21.81.42.21.52.22.22.11.92.22.1
Delta distance traveled before/after self-admin1.31.45.7-0.11.02.41.12.31.10.4-0.40.80.6-0.0
Delta ambulatory time before/after self-admin1.01.13.90.01.02.01.01.91.00.5-0.20.80.60.1
Time in closed arm before self-admin0.00.10.20.30.10.00.20.10.20.30.20.50.20.2
Time in closed arm after self-admin0.50.61.01.00.60.00.70.10.70.90.80.70.91.0
Time in open arm before self-admin0.00.00.1-0.0-0.1-0.3-0.2-0.3-0.2-0.10.3-0.2-0.1-0.0
Time in open arm after self-admin0.00.00.10.10.10.00.10.00.10.1-0.0-0.30.20.2
Sum of active levers in priming session hrs 5-60.40.40.70.40.60.90.70.80.70.50.40.60.60.4
Time to tail flick, vehicle, before self-admin2.82.93.7-1.6-1.7-1.4-1.9-1.5-1.9-1.9-1.5-1.4-1.9-1.8
Time to tail flick, vehicle, after self-admin0.70.81.61.30.5-0.90.5-0.70.51.01.20.50.81.2
Time to tail flick, test, before self-admin0.00.00.0-0.20.0-0.1-0.1-0.1-0.1-0.10.0-0.2-0.2-0.2
Time to tail flick, test, after self-admin0.30.30.6-0.3-0.7-0.8-0.6-0.8-0.6-0.4-0.3-0.6-0.5-0.3
Delta time to tail flick, vehicle, before/after SA0.30.30.70.80.4-0.40.4-0.40.40.60.70.20.60.8
Delta time to tail flick, test, before/after SA1.31.21.5-1.0-1.2-0.9-1.2-1.0-1.2-1.1-0.9-0.9-1.2-1.1
Ambulatory time before self-admin1.51.62.3-0.9-1.3-1.5-1.4-1.5-1.4-1.1-0.8-1.5-1.2-0.9
Ambulatory time after self-admin0.10.10.4-0.4-0.00.6-0.00.5-0.0-0.2-0.7-0.3-0.1-0.3
Total heroin consumption0.10.20.30.30.30.50.40.50.40.3-0.00.60.30.3
Area under the delay curve0.00.00.1-0.3-0.00.2-0.10.2-0.1-0.3-0.3-0.2-0.2-0.3
Delay disc. indifference point, 0s delay0.40.52.0-0.40.51.40.41.30.4-0.1-0.40.30.1-0.3
Delay disc. indifference point, 16s delay0.00.00.0-0.1-0.10.1-0.10.0-0.1-0.1-0.0-0.2-0.1-0.1
Delay disc. indifference point, 2s delay0.60.61.60.40.81.30.91.20.90.60.30.80.70.4
Delay disc. indifference point, 24s delay0.80.81.1-0.7-0.9-1.0-1.0-1.1-1.0-0.8-0.5-1.0-0.8-0.7
Delay disc. indifference point, 4s delay0.00.00.1-0.20.10.3-0.00.3-0.0-0.2-0.2-0.0-0.1-0.2
Delay disc. indifference point, 8s delay0.30.30.4-0.4-0.4-0.5-0.6-0.6-0.6-0.6-0.5-0.5-0.6-0.5
Delay discount exponential model param0.10.10.10.30.1-0.10.2-0.00.20.30.30.20.30.3
Delay discount hyperbolic model param0.00.00.10.2-0.1-0.30.0-0.20.00.10.20.00.10.2
Fecal boli incidents, locomotor time 10.30.40.7-0.4-0.6-0.8-0.6-0.8-0.6-0.4-0.6-0.8-0.5-0.3
Change in fecal boli incidents, locomotor task0.30.30.9-0.60.10.90.00.80.0-0.3-0.60.2-0.2-0.5
Time >=10cm from walls, locomotor time 13.53.64.2-1.8-2.0-1.5-2.0-1.6-2.0-2.0-2.1-2.0-2.0-1.8
Bouts of movement, locomotor time 10.30.30.70.10.50.80.50.80.50.30.50.80.40.1
Total resting periods, locomotor time 10.70.81.30.60.91.10.91.10.90.80.81.10.80.6
Rest time, locomotor task time 17.38.09.53.03.01.83.02.13.03.12.82.73.13.0
Distance moved, locomotor task time 16.97.59.2-3.0-2.9-1.8-3.0-2.0-3.0-3.0-2.6-2.7-3.0-3.0
Vertical activity count, locomotor time 12.82.94.4-2.1-1.8-0.6-1.8-0.8-1.8-2.0-1.9-1.6-1.9-2.0
Time >=10cm from walls, locomotor time 21.61.72.6-1.2-1.4-1.1-1.4-1.2-1.4-1.3-1.6-1.4-1.3-1.2
Bouts of movement, locomotor time 20.40.50.7-0.5-0.7-0.8-0.8-0.9-0.8-0.7-0.3-0.7-0.7-0.6
Total resting periods, locomotor time 20.60.60.9-0.6-0.8-1.0-0.9-1.0-0.9-0.7-0.4-0.8-0.8-0.6
Rest time, locomotor task time 21.11.21.61.21.20.71.20.81.21.21.21.21.21.1
Distance moved, locomotor task time 21.82.12.5-1.6-1.5-0.8-1.5-1.0-1.5-1.6-1.5-1.4-1.6-1.6
Vertical activity count, locomotor time 20.00.00.20.1-0.1-0.4-0.2-0.4-0.2-0.00.0-0.1-0.10.1
Weight adjusted by age0.10.20.3-0.6-0.3-0.1-0.4-0.1-0.4-0.5-0.5-0.3-0.5-0.5
Seeking ratio, delayed vs. immediate footshock1.82.02.51.31.51.31.61.41.61.41.11.41.51.4
Locomotion in novel chamber0.10.10.40.30.0-0.6-0.0-0.5-0.00.20.6-0.10.10.3
Locomotion in novel chamber post-restriction0.50.62.50.3-0.6-1.6-0.6-1.5-0.6-0.10.5-0.4-0.20.2
Progressive ratio0.91.01.51.21.10.41.10.51.11.20.80.91.21.2
Food seeking constrained by brief footshock2.42.94.91.21.82.21.82.21.81.41.41.81.51.1
Seeking ratio, punishment vs. effort0.10.10.5-0.30.10.70.10.60.1-0.20.10.3-0.1-0.4
Run reversals in cocaine runway, females1.31.32.4-0.7-1.2-1.5-1.2-1.5-1.2-0.9-0.9-1.1-1.0-0.7
Run reversals in cocaine runway, males0.40.41.80.3-0.3-1.3-0.5-1.2-0.5-0.10.7-0.5-0.20.1
Latency to leave start box in cocaine runway3.64.05.0-2.0-2.0-1.4-2.1-1.5-2.1-2.1-2.2-2.0-2.1-2.0
Latency to leave start box in cocaine runway, F1.71.82.4-1.4-1.5-0.8-1.4-1.0-1.4-1.4-1.5-1.5-1.4-1.3
Latency to leave start box in cocaine runway, M1.91.93.2-1.6-1.1-0.4-1.4-0.5-1.4-1.6-1.8-1.2-1.6-1.7
Cd content in liver2.32.64.92.01.50.21.50.41.51.82.21.41.71.9
Co content in liver2.73.23.91.71.91.41.91.51.91.92.01.81.91.8
Cu content in liver0.30.30.80.20.40.80.50.80.50.30.60.90.30.1
Fe content in liver0.30.41.20.70.50.40.60.40.60.60.61.10.60.6
K content in liver2.02.04.2-0.7-1.5-2.0-1.5-2.0-1.5-1.1-0.9-1.4-1.2-0.8
Mg content in liver0.60.60.7-0.6-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.8-0.7-0.6
Mn content in liver0.30.30.4-0.3-0.6-0.7-0.6-0.6-0.6-0.5-0.2-0.3-0.6-0.5
Na content in liver2.12.22.6-1.5-1.6-1.1-1.6-1.2-1.6-1.6-1.5-1.5-1.6-1.5
Rb content in liver1.11.31.7-1.2-1.2-0.8-1.3-0.9-1.3-1.3-1.0-0.9-1.3-1.3
Se content in liver0.81.01.31.10.90.51.00.61.01.11.21.11.01.0
Sr content in liver0.30.30.4-0.4-0.6-0.5-0.6-0.5-0.6-0.6-0.6-0.6-0.6-0.5
Zn content in liver0.30.41.80.5-0.3-1.3-0.3-1.2-0.30.20.2-0.30.00.5