Hub : Genes

Mok

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000007850 0.24 0.13 5.6e-17 0.24 0.29 0.28 0.28 4.5e-13 4.9e-16 4.3e-15 1.7e-15
2 BLA mRNA stability ENSRNOG00000007850 0.05 0.04 3.0e-03 0.04 0.04 0.04 0.05 3.7e-03 2.8e-03 4.9e-03 1.5e-03
3 IL gene expression ENSRNOG00000007850 0.25 0.18 2.4e-05 0.19 0.19 0.17 0.18 2.9e-05 2.1e-05 6.7e-05 4.7e-05
4 IL mRNA stability ENSRNOG00000007850 0.26 0.2 1.1e-04 0.19 0.18 0.2 0.21 2.5e-05 4.1e-05 1.3e-05 7.3e-06
5 Liver alternative TSS ENSRNOT00000010529 0.04 0.04 1.9e-04 0.01 0.02 0.02 0.01 8.6e-03 1.4e-03 1.4e-03 7.4e-03
6 Liver alternative TSS ENSRNOT00000010529 0.04 0.03 2.5e-04 0.01 0.02 0.02 0.01 9.4e-03 1.7e-03 2.3e-03 8.2e-03
7 Liver gene expression ENSRNOG00000007850 0.23 0.14 0.0e+00 0.16 0.16 0.16 0.16 1.8e-17 8.4e-18 2.1e-17 1.4e-17
8 Liver isoform ratio ENSRNOT00000010529 0.03 0.02 2.4e-03 0.02 0.02 0.01 0.02 2.0e-03 2.7e-03 2.3e-02 3.0e-03
9 Liver intron excision ratio chr6:129830822:129854465 0.07 0.05 5.0e-09 0.06 0.07 0.06 0.06 1.9e-07 7.6e-08 9.8e-07 1.3e-07
10 Liver intron excision ratio chr6:129840864:129845957 0.05 0.04 8.6e-06 0.04 0.04 0.03 0.03 7.4e-05 8.3e-05 1.7e-04 1.5e-04
11 Liver intron excision ratio chr6:129840864:129854465 0.12 0.07 5.6e-17 0.12 0.11 0.1 0.1 8.3e-13 4.9e-12 2.5e-11 9.7e-12
12 Liver intron excision ratio chr6:129846071:129854465 0.05 0.04 2.7e-05 0.03 0.04 0.03 0.03 1.6e-04 8.9e-05 3.6e-04 2.5e-04
13 NAcc gene expression ENSRNOG00000007850 0.17 0.1 5.6e-17 0.2 0.22 0.2 0.2 1.9e-14 5.7e-16 6.0e-15 7.0e-15
14 NAcc intron excision ratio chr6:129824399:129827668 0.04 0.04 1.5e-03 0.03 0.02 0.03 0.03 4.1e-03 7.7e-03 2.7e-03 2.9e-03
15 NAcc mRNA stability ENSRNOG00000007850 0.04 0.04 1.1e-03 0.04 0.03 0.04 0.04 6.2e-04 1.5e-03 8.4e-04 1.3e-03
16 OFC gene expression ENSRNOG00000007850 0.42 0.19 1.0e-09 0.31 0.28 0.26 0.29 3.6e-08 1.9e-07 6.3e-07 1.1e-07
17 OFC isoform ratio ENSRNOT00000110675 0.14 0.11 2.7e-03 0.09 0.11 0.09 0.09 4.9e-03 1.6e-03 3.4e-03 4.3e-03
18 OFC intron excision ratio chr6:129824399:129827668 0.22 0.25 8.1e-03 0.06 0.04 0.04 0.04 1.8e-02 4.8e-02 4.4e-02 3.7e-02
19 PL gene expression ENSRNOG00000007850 0.34 0.17 0.0e+00 0.32 0.31 0.3 0.31 1.6e-24 6.6e-24 1.4e-23 7.5e-24
20 PL isoform ratio ENSRNOT00000110675 0.07 0.07 5.8e-04 0.05 0.04 0.06 0.05 1.0e-04 3.2e-04 3.2e-05 1.8e-04
21 PL intron excision ratio chr6:129824399:129827668 0.07 0.08 4.6e-04 0.05 0.04 0.04 0.04 1.3e-04 5.3e-04 8.9e-04 2.5e-04
22 PL mRNA stability ENSRNOG00000007850 0.13 0.1 8.0e-07 0.09 0.08 0.07 0.08 4.5e-07 6.9e-07 4.0e-06 1.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail0.20.73.6-0.7-1.3-0.6-0.90.70.70.10.6-0.80.7-0.50.6-0.6-0.9-1.9-0.6-0.9-1.4-0.3-0.3-0.9-0.9
BMI without tail0.51.02.51.10.91.10.9-1.1-1.11.6-1.11.0-0.71.0-1.21.10.8-0.01.20.90.61.31.10.90.3
Body weight0.62.63.41.61.31.71.5-1.6-1.61.8-1.71.6-1.71.8-1.71.71.71.31.71.61.21.71.61.51.5
Epididymis fat weight3.07.17.9-2.8-2.5-2.7-2.72.72.7-2.42.8-2.82.8-2.72.7-2.7-2.6-2.7-2.6-2.8-2.6-2.7-2.4-2.4-2.7
Glucose0.10.21.20.2-0.30.1-0.0-0.1-0.1-0.2-0.30.2-0.70.4-0.10.1-0.21.10.10.2-0.20.0-0.7-0.01.1
Heart weight0.00.00.2-0.1-0.3-0.1-0.20.10.1-0.00.0-0.10.3-0.00.1-0.1-0.4-0.4-0.2-0.1-0.2-0.2-0.3-0.0-0.2
Left kidney weight0.61.72.11.41.11.41.2-1.4-1.41.4-1.31.4-1.51.5-1.41.41.21.31.31.41.11.40.91.31.5
Right kidney weight0.41.01.71.00.91.01.0-1.0-1.00.9-1.01.0-1.11.1-1.01.01.21.30.71.01.11.00.91.01.1
Tail length3.09.011.03.03.33.03.1-3.0-3.12.8-3.23.1-2.73.1-3.03.03.03.33.03.13.02.92.43.12.6
Length with tail2.59.113.03.03.22.93.0-3.0-3.02.5-3.03.1-2.93.0-2.92.93.43.62.93.13.22.82.63.13.0
Length without tail0.30.71.60.70.70.70.8-0.7-0.70.4-0.70.8-1.00.8-0.70.71.11.20.60.81.00.60.80.81.2
Liver weight, left4.97.99.92.82.92.82.8-2.8-2.82.7-3.12.8-2.53.1-2.82.83.02.52.82.92.82.72.72.82.5
Liver weight, right0.20.31.30.40.30.40.3-0.4-0.40.4-0.60.3-0.60.7-0.40.41.20.50.40.40.30.40.90.40.6
Parametrial fat weight0.50.92.30.90.90.90.8-0.9-0.91.1-0.90.9-0.80.8-0.90.91.50.41.00.90.70.91.50.90.6
Retroperitoneal fat weight0.00.10.40.10.30.20.2-0.2-0.10.3-0.10.1-0.00.2-0.20.10.60.00.10.10.20.20.70.0-0.2
Intraocular pressure0.10.20.5-0.4-0.3-0.4-0.40.40.4-0.40.7-0.40.5-0.70.4-0.4-0.3-0.2-0.3-0.4-0.4-0.5-0.3-0.4-0.1
Extensor digitorum longus weight5.723.026.35.04.84.94.7-4.9-5.04.7-4.75.0-4.84.8-4.95.04.64.65.15.04.65.04.04.94.3
Soleus weight0.00.10.5-0.3-0.3-0.3-0.30.30.3-0.30.5-0.30.5-0.40.3-0.3-0.3-0.5-0.2-0.3-0.2-0.2-0.1-0.4-0.7
Tibialis anterior weight0.51.82.91.41.41.41.3-1.4-1.41.4-1.21.4-1.21.3-1.41.41.60.91.61.41.41.41.71.50.9
Tibia length0.30.82.20.80.90.70.8-0.8-0.80.5-0.40.8-1.50.4-0.70.81.11.30.60.81.00.60.70.91.3
Number of licking bursts0.91.11.81.01.21.11.1-1.1-1.11.2-1.31.0-1.01.3-1.11.10.80.41.11.01.21.11.01.10.6
Food consumed during 24 hour testing period0.30.40.90.60.60.60.6-0.6-0.60.6-0.50.6-0.60.5-0.60.60.90.30.60.60.60.61.00.40.3
Times rat made contact with spout0.10.10.40.1-0.20.0-0.1-0.0-0.0-0.1-0.10.1-0.60.1-0.00.10.10.60.00.1-0.30.0-0.3-0.10.7
Mean time between licks in bursts0.50.72.3-0.8-0.9-0.8-0.80.80.8-0.61.0-0.80.9-0.90.8-0.8-0.7-1.5-0.7-0.9-0.8-0.7-0.2-0.7-1.1
Mean num. licks in bursts1.01.22.0-1.0-1.4-1.1-1.31.11.1-1.31.4-1.00.8-1.31.1-1.1-0.8-0.1-1.1-1.0-1.4-1.1-1.3-1.2-0.3
Std. dev. time between licks in bursts1.51.82.1-1.3-1.4-1.4-1.41.41.4-1.41.2-1.31.2-1.41.4-1.4-1.4-1.2-1.4-1.3-1.4-1.4-1.3-1.3-1.1
Water consumed over 24 hours2.32.74.11.71.51.61.6-1.6-1.71.5-1.51.7-2.01.7-1.61.61.51.91.61.71.61.61.11.62.0
Indifference point 0 sec1.52.54.01.61.61.61.4-1.6-1.61.3-1.31.6-1.71.2-1.51.61.62.01.61.71.51.61.01.61.9
Indifference point AUC3.23.75.81.92.31.92.1-1.9-1.91.9-1.91.9-1.51.9-1.91.92.41.41.81.92.11.82.41.91.5
Indifference point function ln k0.10.20.90.3-0.40.2-0.1-0.1-0.20.0-0.20.3-0.70.2-0.20.2-0.50.80.20.3-0.40.3-1.00.20.8
Indifference point function log k0.10.20.90.3-0.40.2-0.1-0.1-0.20.0-0.20.3-0.70.2-0.20.2-0.50.80.20.3-0.40.3-1.00.20.8
Delay discounting total patch changes 0 sec1.62.74.21.71.71.61.5-1.6-1.71.4-1.41.7-1.81.4-1.61.61.62.11.61.71.51.71.01.72.0
Delay discounting total patch changes 12 sec2.83.75.61.92.21.92.0-1.9-1.91.8-1.71.9-1.61.7-1.91.92.41.71.81.92.12.02.22.11.6
Delay discounting total patch changes 18 sec0.30.40.80.70.90.70.7-0.7-0.70.6-0.50.7-0.60.5-0.70.70.80.50.60.70.70.60.70.60.6
Delay discounting total patch changes 24 sec1.01.23.20.91.81.11.3-1.1-1.11.1-0.80.9-0.40.7-1.01.01.50.41.01.01.61.01.71.20.5
Delay discounting total patch changes 6 sec3.35.16.32.22.52.32.4-2.3-2.32.3-2.22.2-1.92.2-2.32.32.51.72.22.22.42.42.52.41.9
Delay discounting time to switch 0 sec7.711.713.9-3.5-3.4-3.4-3.43.53.5-3.13.4-3.63.2-3.53.4-3.5-3.7-3.7-3.4-3.6-3.3-3.3-2.9-3.4-3.3
Delay discounting water rate 0 sec13.120.926.94.84.54.64.5-4.7-4.74.2-4.54.8-4.64.5-4.64.74.55.24.64.84.44.63.54.44.7
Delay discounting water rate 12 sec11.417.120.34.24.24.24.1-4.2-4.24.0-4.44.2-3.84.5-4.14.24.34.24.24.24.14.03.73.94.0
Delay discounting water rate 18 sec3.54.69.32.12.02.11.9-2.1-2.11.7-2.12.2-2.42.1-2.02.12.53.12.02.22.01.91.51.92.7
Delay discounting water rate 24 sec3.75.07.22.32.02.22.1-2.2-2.32.0-2.22.3-2.22.2-2.22.32.72.62.12.32.02.32.12.02.4
Delay discounting water rate 6 sec2.63.84.92.11.92.01.9-2.0-2.01.7-1.92.1-1.82.0-2.02.01.92.22.02.11.91.91.41.92.0
Locomotor activity0.00.00.1-0.00.0-0.1-0.10.10.1-0.20.3-0.00.0-0.30.1-0.10.1-0.1-0.1-0.0-0.2-0.00.1-0.2-0.3
Locomotor testing distance0.10.10.6-0.2-0.4-0.3-0.50.30.3-0.50.6-0.20.2-0.50.3-0.3-0.2-0.2-0.3-0.2-0.8-0.2-0.5-0.4-0.4
Locomotor testing rearing2.84.56.4-2.0-2.3-2.1-2.22.12.1-1.92.4-2.02.3-2.42.0-2.0-1.5-2.4-1.9-2.1-2.5-1.9-1.2-2.1-2.5
Light reinforcement 10.00.00.1-0.1-0.3-0.1-0.10.10.1-0.10.4-0.10.2-0.30.1-0.1-0.20.1-0.1-0.1-0.2-0.0-0.3-0.2-0.1
Light reinforcement 21.52.02.7-1.4-1.5-1.5-1.41.51.5-1.51.5-1.41.1-1.61.5-1.5-1.6-0.9-1.4-1.4-1.4-1.5-1.6-1.4-0.9
Reaction time number correct1.01.42.61.20.91.21.1-1.2-1.21.0-1.41.3-1.51.5-1.21.20.81.61.11.30.91.10.40.91.6
Reaction time mean minus median0.30.41.30.50.80.60.7-0.6-0.60.7-0.30.5-0.40.2-0.60.50.90.30.50.51.00.61.10.70.5
Reaction time mean minus median AUC0.20.20.70.30.60.40.5-0.4-0.40.5-0.00.3-0.4-0.1-0.40.40.70.30.40.30.70.40.80.60.4
Reaction time num false alarms0.30.31.00.50.70.50.5-0.5-0.50.3-0.60.5-1.00.7-0.50.50.50.90.50.60.70.40.20.50.8
Reaction time num false alarms AUC0.50.81.70.81.00.80.8-0.8-0.80.5-0.90.8-1.30.9-0.70.80.81.30.80.91.00.70.50.71.1
Reaction time trials correct on left1.01.42.61.20.91.21.1-1.2-1.21.0-1.41.3-1.51.5-1.21.20.81.61.11.30.91.10.40.91.6
Reaction time trials on left1.01.52.61.31.01.21.1-1.2-1.21.0-1.41.3-1.51.5-1.21.20.81.61.11.31.01.10.50.91.6
Reaction time mean0.10.10.8-0.10.1-0.10.00.10.10.20.3-0.20.8-0.40.0-0.1-0.1-0.90.0-0.20.3-0.00.50.0-0.7
Reaction time mean AUC0.10.10.40.00.10.10.2-0.1-0.10.30.2-0.00.6-0.3-0.10.10.0-0.60.2-0.00.30.10.50.2-0.4
Median of all reaction times0.10.10.9-0.2-0.1-0.1-0.10.10.20.10.4-0.20.9-0.40.1-0.1-0.3-0.9-0.0-0.20.1-0.10.2-0.1-0.8
Reaction time omissions2.83.75.01.92.12.02.1-2.0-2.02.1-2.01.9-1.11.9-2.02.02.01.52.01.92.22.02.01.91.5
Reaction time false alarm rate0.10.10.40.30.60.30.3-0.3-0.30.2-0.20.3-0.60.3-0.30.30.50.50.30.30.60.20.40.40.4
Reaction time premature initiation rate0.81.12.51.01.21.01.1-1.0-1.01.0-0.81.0-0.80.9-1.01.01.50.71.01.01.31.11.61.10.8
Reaction time premature initiations1.31.82.41.31.41.31.3-1.3-1.41.2-1.21.4-1.31.4-1.31.31.51.31.31.41.51.41.51.21.4
Std. dev. reaction times0.40.51.80.51.00.60.8-0.7-0.60.8-0.30.5-0.20.2-0.60.60.90.00.60.51.10.71.30.80.3
Reaction time trials completed1.01.52.61.31.01.21.1-1.2-1.21.0-1.41.3-1.51.5-1.21.20.81.61.11.31.01.10.50.91.6
Reaction time trials AUC1.21.72.81.41.11.31.3-1.3-1.31.1-1.61.4-1.51.6-1.31.31.01.71.31.41.11.30.71.01.7
Social response proportion0.70.81.21.00.91.01.0-0.9-0.91.1-0.80.9-0.60.8-1.01.00.80.51.00.90.81.00.80.70.7
Social responses0.10.20.6-0.4-0.5-0.4-0.40.40.4-0.30.7-0.40.8-0.70.4-0.4-0.3-0.3-0.3-0.4-0.4-0.3-0.3-0.3-0.5
Social time1.11.41.81.21.21.21.3-1.2-1.21.1-1.11.2-1.11.1-1.21.21.21.21.11.21.31.11.11.11.3
Conditioned locomotion0.20.20.80.40.50.40.4-0.4-0.40.2-0.20.5-0.70.1-0.40.40.60.90.40.50.50.40.20.40.8
Cocaine response after cond. corrected0.10.20.5-0.4-0.3-0.3-0.30.30.4-0.20.1-0.40.7-0.10.3-0.4-0.6-0.6-0.3-0.4-0.3-0.3-0.4-0.4-0.6
Cocaine response after cond. not corrected0.70.71.8-0.9-0.6-0.8-0.70.80.8-0.60.6-0.91.3-0.50.8-0.8-0.8-1.3-0.8-0.9-0.7-0.8-0.4-0.9-1.2
Cocaine response before conditioning1.82.13.4-1.6-1.3-1.5-1.41.51.5-1.41.5-1.61.6-1.51.5-1.5-0.7-1.9-1.6-1.6-1.2-1.5-0.4-1.6-1.6
Saline control response1.62.13.1-1.5-1.6-1.5-1.51.51.5-1.71.6-1.41.0-1.51.5-1.5-1.2-0.8-1.6-1.4-1.4-1.5-1.4-1.8-0.8
Condit. Reinf. active minus inactive responses0.80.91.41.00.81.01.0-1.0-1.01.2-1.11.0-0.61.2-1.11.00.80.61.01.00.91.11.01.00.6
Condit. Reinf. active-inactive response ratio0.50.50.80.80.60.80.7-0.8-0.70.8-0.70.8-0.90.9-0.80.80.50.80.70.70.60.80.30.80.7
Condit. Reinf. active responses0.10.20.60.40.30.40.5-0.4-0.40.6-0.40.40.20.6-0.50.40.5-0.20.40.40.40.50.80.5-0.1
Condit. Reinf. inactive responses0.40.51.2-0.7-0.7-0.7-0.60.70.7-0.50.7-0.71.0-0.60.6-0.7-0.3-1.1-0.6-0.7-0.6-0.6-0.0-0.6-0.8
Condit. Reinf. lever presses0.81.02.9-1.0-0.9-0.9-0.80.90.9-0.60.9-1.01.7-0.90.9-0.9-1.1-1.6-0.9-1.0-0.8-0.8-0.5-0.9-1.6
Condit. Reinf. lever reinforcers received0.10.20.40.40.30.40.4-0.4-0.40.6-0.30.40.20.5-0.40.40.3-0.20.40.30.30.50.60.4-0.1
Pavlov. Cond. lever latency1.62.15.31.51.21.41.3-1.4-1.41.2-1.31.5-2.31.4-1.41.41.32.01.41.51.11.30.71.32.1
Pavlov. Cond. magazine entry latency3.43.94.6-2.1-1.8-2.0-1.92.02.0-1.81.9-2.12.0-2.02.0-2.1-1.8-2.0-2.1-2.1-1.7-2.0-1.4-2.1-2.0
Pavlov. Cond. change in total contacts3.14.46.3-2.2-1.8-2.1-2.02.12.1-1.92.0-2.22.3-1.92.1-2.1-2.2-2.5-2.2-2.2-1.8-2.1-1.6-2.1-2.4
Pavlov. Cond. index score3.34.36.8-2.2-1.9-2.1-1.92.12.1-1.81.9-2.22.6-1.92.1-2.1-1.9-2.5-2.1-2.2-1.7-2.0-1.3-2.1-2.5
Pavlov. Cond. latency score3.24.16.6-2.1-1.8-2.0-1.92.02.1-1.71.9-2.12.6-1.92.0-2.1-1.8-2.4-2.1-2.1-1.7-2.0-1.2-2.1-2.5
Pavlov. Cond. lever contacts1.31.86.0-1.3-1.0-1.2-1.11.21.2-0.81.1-1.32.4-1.11.2-1.2-1.1-2.2-1.2-1.3-0.9-1.1-0.3-1.1-2.3
Pavlov. Cond. magazine entry number2.32.84.21.81.51.71.6-1.7-1.71.4-1.61.8-1.81.7-1.71.71.42.11.71.81.31.60.81.72.0
Pavlov. Cond. intertrial magazine entries1.62.14.51.51.31.41.3-1.4-1.41.0-1.31.5-1.71.5-1.41.41.62.11.41.51.11.30.91.31.8
Pavlov. Cond. lever-magazine prob. diff.4.15.37.4-2.4-2.1-2.3-2.22.32.4-2.02.1-2.42.7-2.22.3-2.4-2.2-2.6-2.4-2.4-2.0-2.3-1.6-2.4-2.7
Pavlov. Cond. response bias1.92.66.3-1.6-1.4-1.5-1.41.61.6-1.21.4-1.72.5-1.41.5-1.6-1.4-2.5-1.5-1.7-1.3-1.4-0.6-1.4-2.5
Conditioned reinforcement - actives0.50.51.80.80.70.70.6-0.7-0.70.5-0.60.8-0.80.6-0.70.70.61.30.70.80.50.70.00.70.9
Conditioned reinforcement - inactives0.10.10.40.30.40.30.3-0.3-0.30.2-0.20.3-0.00.2-0.30.30.60.50.30.30.20.30.40.30.1
Conditioned locomotion1.62.02.6-1.4-1.2-1.4-1.41.41.4-1.41.6-1.41.5-1.61.4-1.4-1.2-1.5-1.4-1.4-1.3-1.4-0.9-1.5-1.5
Intermittent access intake day 1-15 change2.82.83.6-1.7-1.5-1.7-1.51.71.7-1.81.5-1.71.8-1.51.7-1.7-1.5-1.7-1.8-1.7-1.4-1.7-1.3-1.8-1.9
Intermittent access intake escalation3.23.24.1-1.8-1.6-1.8-1.61.81.8-1.91.6-1.81.9-1.61.8-1.8-1.6-1.8-1.9-1.8-1.6-1.8-1.4-2.0-2.0
Intermittent access intake escalation 20.60.61.0-0.8-0.7-0.8-0.60.80.8-0.90.7-0.80.8-0.70.8-0.8-0.9-0.8-0.9-0.8-0.6-0.8-0.8-1.0-0.8
Intermitt. access day 1 inactive lever presses1.21.32.51.11.11.11.2-1.1-1.10.9-1.21.2-1.31.1-1.11.11.21.61.11.21.11.00.81.21.2
Intermitt. access day 15 inactive lever presses0.20.21.30.50.30.40.3-0.4-0.40.2-0.40.5-0.50.4-0.40.40.21.20.40.50.20.4-0.30.40.7
Intermitt. access escalation Index2.11.92.61.31.31.41.4-1.4-1.41.5-1.61.3-1.31.6-1.41.41.40.91.31.31.41.41.61.21.1
Intermittent access day 1 total infusions0.00.00.1-0.10.1-0.0-0.20.10.10.10.2-0.10.3-0.30.0-0.10.0-0.40.0-0.1-0.2-0.00.10.1-0.3
Intermittent access day 15 total infusions1.41.63.0-1.3-1.0-1.2-1.11.21.3-1.11.2-1.31.6-1.21.2-1.3-1.0-1.6-1.3-1.3-1.2-1.2-0.7-1.2-1.7
Intermittent access terminal intake (last 3 days)1.41.53.2-1.3-0.9-1.2-1.11.21.2-1.01.2-1.31.7-1.31.2-1.2-1.0-1.5-1.0-1.3-1.1-1.2-0.8-1.2-1.8
Intermittent access total infusions0.40.51.0-0.7-0.3-0.7-0.60.70.7-0.60.7-0.71.0-0.80.7-0.7-0.5-0.9-0.7-0.7-0.5-0.7-0.4-0.5-1.0
Intermittent access day 1 locomotion0.50.51.1-0.8-0.5-0.7-0.70.70.7-0.60.9-0.80.9-0.90.7-0.7-0.2-1.0-0.7-0.8-0.5-0.70.1-0.4-1.0
Intermittent access day 15 total locomotion0.40.41.1-0.7-0.3-0.6-0.50.60.6-0.60.7-0.70.9-0.70.6-0.6-0.1-1.0-0.7-0.7-0.3-0.60.1-0.4-1.1
Intermittent access total locomotion0.50.61.4-0.8-0.3-0.8-0.60.80.8-0.70.9-0.81.0-0.90.8-0.8-0.2-1.1-0.8-0.8-0.3-0.80.1-0.7-1.2
Intermittent access standard deviation4.04.35.2-2.1-2.1-2.1-2.02.12.1-2.01.9-2.12.2-1.92.1-2.1-1.8-2.3-2.1-2.2-2.1-2.1-1.5-2.2-2.2
Cocaine induced anxiety3.13.65.11.91.91.91.9-1.9-1.91.8-1.81.9-1.81.8-1.91.91.92.11.91.91.91.91.52.31.8
Post-drug Anxiety2.62.93.31.71.71.71.7-1.7-1.71.6-1.51.7-1.81.5-1.71.71.81.81.71.71.71.71.51.81.8
Baseline Anxiety1.41.52.9-1.3-1.1-1.2-1.21.21.2-1.21.2-1.31.1-1.21.2-1.2-0.9-1.4-1.2-1.3-1.2-1.2-0.6-1.7-1.1
Lifetime Intake0.30.40.8-0.6-0.3-0.6-0.60.60.6-0.50.7-0.60.9-0.80.6-0.6-0.5-0.7-0.6-0.6-0.6-0.6-0.5-0.4-0.9
Incentive Sensitization - Responses0.10.10.50.30.60.40.4-0.4-0.40.4-0.30.30.20.2-0.40.30.60.00.40.30.50.40.70.3-0.0
Incentive Sensitization - Breakpoint0.20.20.50.40.70.40.5-0.4-0.40.5-0.40.40.10.3-0.40.40.70.10.40.40.50.40.70.30.0
Progressive ratio test 1 active lever presses0.20.20.5-0.4-0.4-0.4-0.50.40.4-0.30.5-0.40.4-0.50.4-0.4-0.3-0.1-0.3-0.4-0.7-0.3-0.5-0.4-0.6
Progressive ratio test 1 breakpoint0.30.30.6-0.5-0.6-0.5-0.60.50.5-0.50.6-0.50.6-0.70.5-0.5-0.4-0.4-0.4-0.5-0.8-0.5-0.4-0.6-0.7
Progressive ratio test 1 inactive lever presses0.80.92.10.90.80.90.9-0.9-0.90.6-0.81.0-1.00.8-0.90.91.11.50.91.00.80.90.81.00.9
Progressive ratio test 2 active lever presses0.00.00.2-0.00.30.0-0.0-0.00.00.00.2-0.00.5-0.2-0.0-0.00.3-0.20.0-0.00.00.00.30.0-0.4
Progressive ratio test 2 breakpoint0.00.00.2-0.00.30.00.0-0.0-0.00.10.2-0.00.4-0.2-0.00.00.3-0.20.1-0.00.00.00.30.1-0.4
Progressive ratio test 2 inactive lever presses0.60.71.40.91.00.90.8-0.9-0.90.9-0.80.9-0.50.8-0.90.90.90.91.00.90.60.90.71.20.5
Total sessions with >9 infusions0.91.01.8-0.9-0.8-0.9-1.01.01.0-0.91.0-0.91.1-1.00.9-0.9-1.0-0.9-0.9-0.9-1.2-0.9-1.0-0.8-1.4
Short access day 1 total inactive lever presses0.10.10.4-0.3-0.4-0.3-0.40.30.3-0.30.4-0.30.4-0.40.3-0.3-0.2-0.4-0.3-0.3-0.5-0.3-0.1-0.2-0.6
Short access day 10 total inactive lever presses0.80.91.30.91.00.91.0-0.9-0.90.9-0.90.9-0.90.9-0.90.91.10.90.90.91.10.91.10.91.0
Short access day 1 total infusions0.10.10.30.30.20.30.3-0.3-0.30.3-0.40.3-0.20.4-0.30.30.20.40.30.30.00.3-0.00.50.1
Short access day 10 total infusions0.50.60.9-0.7-0.7-0.7-0.80.70.7-0.70.9-0.80.7-0.90.7-0.7-0.8-0.4-0.7-0.8-0.9-0.7-0.9-0.7-0.5
Short access total infusions0.30.40.6-0.6-0.5-0.6-0.60.60.6-0.50.7-0.60.7-0.70.6-0.6-0.6-0.5-0.5-0.6-0.8-0.6-0.8-0.4-0.8
Short access day 1 locomotion1.11.11.5-1.2-0.8-1.1-1.01.11.1-1.11.2-1.21.2-1.21.1-1.2-0.6-1.0-1.2-1.2-0.8-1.2-0.4-1.0-1.2
Short access day 10 total locomotion0.70.71.6-0.9-0.7-0.9-0.70.90.9-0.80.9-0.91.0-0.90.9-0.9-0.3-1.3-0.9-0.9-0.4-0.90.2-0.8-1.1
Short access total locomotion0.20.20.5-0.5-0.2-0.5-0.30.40.5-0.50.5-0.50.5-0.60.5-0.50.0-0.7-0.5-0.5-0.1-0.50.3-0.3-0.6
Compulsive drug intake0.00.00.00.10.20.10.0-0.1-0.10.1-0.10.10.20.1-0.10.10.20.2-0.00.1-0.00.10.0-0.0-0.0
One hour access (0.3 mA shock)0.00.00.30.10.50.10.2-0.1-0.10.00.00.10.2-0.1-0.10.10.5-0.10.10.10.30.10.40.1-0.1
One hour access (shock baseline)0.20.20.3-0.5-0.1-0.4-0.30.40.4-0.50.5-0.40.4-0.50.5-0.5-0.4-0.6-0.4-0.4-0.3-0.5-0.3-0.4-0.5
Number of responses in last shaping day0.10.10.20.10.20.20.3-0.2-0.10.30.00.10.1-0.1-0.20.2-0.1-0.40.10.10.40.20.30.5-0.1
Context. condit. distance diff. score0.30.31.10.70.30.60.4-0.6-0.60.3-0.50.7-0.80.5-0.60.60.41.00.50.70.20.6-0.10.60.9
Locomotion velocity, session 10.40.51.30.60.80.60.7-0.6-0.60.6-0.50.6-0.10.4-0.60.61.10.80.60.60.80.71.00.60.3
Locomotion distance, session 10.20.21.6-0.4-0.2-0.3-0.30.40.4-0.20.2-0.41.3-0.20.3-0.4-0.0-0.9-0.3-0.4-0.3-0.40.3-0.4-1.0
Locomotion velocity, session 20.10.10.5-0.20.0-0.1-0.10.10.1-0.00.0-0.20.7-0.10.1-0.10.3-0.6-0.1-0.20.0-0.20.5-0.3-0.6
Locomotion distance, session 20.20.31.2-0.5-0.3-0.5-0.50.50.5-0.40.2-0.51.1-0.10.5-0.5-0.3-0.9-0.4-0.5-0.4-0.6-0.0-0.6-0.9
Locomotion velocity, session 31.51.82.5-1.4-1.3-1.4-1.31.41.4-1.61.5-1.40.9-1.41.4-1.4-1.1-0.9-1.4-1.3-1.2-1.5-1.2-1.3-1.1
Locomotion distance, session 30.40.40.9-0.7-0.6-0.7-0.60.70.7-0.91.0-0.60.2-0.80.7-0.7-0.3-0.0-0.7-0.6-0.5-0.7-0.5-0.8-0.2
Stereotopy head waving bouts, day 30.10.10.20.40.30.40.3-0.4-0.40.4-0.40.4-0.40.4-0.40.40.30.10.30.40.30.40.40.40.2
Stereotopy head waving duration, day 30.20.20.40.50.50.50.5-0.5-0.50.5-0.60.5-0.10.5-0.50.50.40.30.40.50.40.50.40.6-0.0
Locomotion velocity, session 73.33.64.9-2.0-1.7-2.0-1.92.01.9-2.22.1-1.91.5-2.12.0-2.0-1.9-1.1-2.1-1.9-1.8-2.1-2.1-1.9-1.4
Locomotion distance, session 72.63.34.1-1.9-1.7-1.9-1.81.91.9-2.02.0-1.91.6-2.01.9-1.9-1.6-1.2-2.0-1.8-1.6-1.9-1.7-1.9-1.3
Stereotopy head waving bouts, day 70.10.11.10.30.20.20.2-0.2-0.2-0.00.00.3-0.7-0.0-0.20.20.21.00.20.30.20.2-0.20.20.6
Stereotopy head waving duration, day 70.10.10.40.30.30.30.3-0.3-0.30.2-0.10.3-0.60.1-0.30.30.10.60.30.30.30.3-0.00.20.4
Locomotion velocity, session 80.00.00.10.00.10.00.1-0.0-0.0-0.0-0.00.10.10.0-0.00.00.3-0.00.00.10.1-0.00.30.10.0
Locomotion distance, session 80.40.61.0-0.7-0.9-0.8-0.90.80.8-0.80.7-0.70.9-0.70.8-0.8-0.7-0.7-0.8-0.7-1.0-0.8-0.7-0.8-0.7
Degree of sensitization distance0.20.20.4-0.5-0.4-0.5-0.50.50.5-0.40.3-0.50.4-0.50.5-0.5-0.6-0.4-0.5-0.5-0.5-0.5-0.6-0.5-0.1
Degree of sensitization stereotypy0.10.10.3-0.2-0.2-0.2-0.20.20.2-0.40.4-0.2-0.2-0.40.2-0.2-0.10.6-0.3-0.1-0.1-0.2-0.4-0.30.2
Condit. Reinf. active minus inactive responses0.30.40.6-0.7-0.7-0.7-0.70.70.7-0.60.5-0.70.4-0.40.7-0.7-0.4-0.6-0.8-0.7-0.6-0.6-0.4-0.8-0.2
Condit. Reinf. active-inactive response ratio1.61.72.1-1.4-1.5-1.3-1.41.31.4-1.21.2-1.41.2-1.21.3-1.3-1.2-1.4-1.4-1.4-1.4-1.2-1.0-1.4-1.1
Condit. Reinf. active responses0.30.40.7-0.7-0.7-0.7-0.60.70.7-0.70.4-0.70.6-0.40.7-0.7-0.4-0.5-0.8-0.7-0.5-0.7-0.3-0.8-0.4
Condit. Reinf. inactive responses1.01.11.61.11.01.11.1-1.1-1.10.9-1.31.1-0.81.1-1.11.11.11.21.01.11.21.00.91.00.9
Incentive salience index mean0.30.40.7-0.7-0.7-0.7-0.70.70.7-0.70.4-0.70.4-0.40.7-0.7-0.4-0.6-0.8-0.7-0.6-0.7-0.3-0.8-0.2
Condit. Reinf. lever presses0.40.50.7-0.8-0.8-0.8-0.80.80.8-0.80.4-0.80.5-0.40.8-0.8-0.5-0.5-0.8-0.7-0.7-0.8-0.5-0.8-0.4
Time in familiar zone, hab. session 12.32.22.8-1.5-1.6-1.5-1.41.51.5-1.51.1-1.51.7-1.11.5-1.5-1.6-1.3-1.5-1.5-1.4-1.5-1.4-1.5-1.5
Time in novel zone, hab. session 10.70.71.00.90.90.90.8-0.9-0.91.0-0.60.8-0.80.5-0.90.90.90.80.90.80.80.90.80.80.7
Total zone transitions, hab. session 10.81.21.5-1.2-1.1-1.1-1.11.11.1-1.10.9-1.11.2-0.71.1-1.1-0.9-1.1-1.1-1.1-1.1-1.2-0.8-1.0-1.1
Total locomotion distance, hab. session 10.00.10.2-0.3-0.1-0.3-0.20.30.2-0.40.1-0.20.4-0.10.3-0.3-0.1-0.1-0.3-0.2-0.0-0.3-0.1-0.2-0.2
Locomotion velocity, hab. session 10.00.10.10.20.30.20.2-0.2-0.20.0-0.40.3-0.10.4-0.20.20.30.30.20.30.30.20.30.20.3
Time in familiar zone, hab. session 21.81.92.4-1.4-1.4-1.4-1.31.41.4-1.41.2-1.41.3-1.41.4-1.4-1.5-1.4-1.4-1.4-1.3-1.3-1.3-1.4-1.2
Time in novel zone, hab. session 21.11.11.71.11.21.11.1-1.1-1.11.3-0.91.1-0.51.1-1.21.11.10.51.21.11.11.11.21.10.5
Total zone transitions, hab. session 20.40.51.7-0.7-0.6-0.7-0.60.70.7-0.60.5-0.71.3-0.50.7-0.7-0.2-1.2-0.6-0.7-0.5-0.70.1-0.5-1.1
Total locomotion distance, hab. session 20.40.61.70.70.80.70.8-0.7-0.70.6-0.70.7-0.20.6-0.70.71.10.30.70.71.10.71.30.80.4
Locomotion velocity, hab. session 20.30.40.90.60.70.50.6-0.6-0.60.4-0.60.6-0.20.6-0.50.60.90.50.50.60.90.51.00.60.4
Novel to familiar place preference ratio0.10.10.2-0.2-0.3-0.2-0.30.20.2-0.10.5-0.20.3-0.50.2-0.2-0.5-0.4-0.1-0.2-0.4-0.2-0.4-0.2-0.1
Novelty place preference0.00.00.1-0.0-0.2-0.0-0.10.00.00.10.3-0.00.2-0.40.0-0.0-0.3-0.30.1-0.1-0.3-0.0-0.2-0.1-0.0
Time in novel zone, NPP test0.00.00.10.0-0.2-0.0-0.10.00.00.10.3-0.00.2-0.3-0.00.0-0.2-0.20.1-0.0-0.30.0-0.2-0.10.1
Total zone transitions, NPP test0.10.21.30.10.30.10.2-0.1-0.10.2-0.30.10.80.3-0.10.10.8-0.60.20.00.30.11.10.0-0.5
Total locomotion distance, NPP test0.00.10.50.10.20.10.2-0.1-0.10.0-0.10.20.10.0-0.10.10.70.10.10.20.40.10.7-0.00.1
Locomotion velocity, NPP test0.10.10.50.20.30.20.3-0.2-0.20.2-0.20.30.10.2-0.20.20.60.10.20.30.50.30.70.10.1
Pavlov. Cond. lever latency0.20.30.90.60.60.60.6-0.6-0.60.5-0.30.6-0.70.4-0.60.60.00.90.50.60.40.5-0.30.50.6
Pavlov. Cond. magazine entry latency2.02.54.6-1.6-1.7-1.6-1.71.61.6-1.71.3-1.61.0-1.51.6-1.6-2.1-1.0-1.6-1.6-1.7-1.6-2.1-1.6-0.9
Pavlov. Cond. change in total contacts0.40.41.1-0.6-0.7-0.6-0.70.60.6-0.50.4-0.61.0-0.50.6-0.6-0.6-0.8-0.5-0.7-0.7-0.5-0.4-0.6-0.9
Pavlov. Cond. index score0.81.01.3-1.0-1.1-1.0-1.01.01.0-0.90.7-1.01.0-0.91.0-1.0-1.0-1.1-1.0-1.0-1.0-1.0-0.8-1.0-0.8
Pavlov. Cond. latency score0.40.40.9-0.7-0.8-0.7-0.70.70.7-0.60.4-0.70.8-0.50.7-0.7-0.7-0.9-0.6-0.7-0.7-0.6-0.4-0.6-0.6
Pavlov. Cond. lever contacts0.50.61.1-0.8-0.8-0.8-0.80.80.8-0.70.5-0.80.8-0.60.8-0.8-0.4-1.0-0.7-0.8-0.8-0.7-0.2-0.7-0.8
Pavlov. Cond. magazine entry number1.51.93.11.31.61.41.5-1.4-1.41.3-1.21.4-1.11.3-1.41.41.81.31.31.41.61.31.61.41.1
Pavlov. Cond. intertrial magazine entries2.93.55.91.81.71.81.8-1.8-1.81.4-1.81.9-2.31.9-1.81.82.02.41.71.91.91.71.41.82.3
Pavlov. Cond. lever-magazine prob. diff.0.70.91.0-1.0-1.0-1.0-1.01.01.0-0.90.7-1.00.9-0.91.0-1.0-1.0-0.9-0.9-1.0-1.0-0.9-0.9-0.9-0.7
Pavlov. Cond. response bias2.22.73.0-1.7-1.7-1.7-1.71.71.7-1.71.5-1.71.4-1.61.7-1.7-1.6-1.4-1.7-1.7-1.7-1.7-1.5-1.7-1.3
Bone: apparent density0.50.81.4-0.8-1.1-0.9-0.90.90.9-1.01.0-0.80.7-0.90.9-0.9-1.1-0.4-1.0-0.8-1.0-0.9-1.2-1.0-0.4
Bone surface0.00.00.2-0.1-0.3-0.1-0.10.10.1-0.10.3-0.10.3-0.40.1-0.1-0.4-0.1-0.2-0.1-0.2-0.1-0.3-0.3-0.2
Bone volume0.30.51.0-0.6-0.8-0.6-0.60.60.6-0.70.7-0.60.7-0.70.6-0.6-1.0-0.4-0.6-0.6-0.8-0.6-1.0-0.8-0.5
Bone: connectivity density0.00.00.00.1-0.00.00.1-0.0-0.00.00.10.10.2-0.2-0.10.1-0.00.10.00.10.10.10.0-0.00.1
Bone: cortical apparent density5.57.19.62.72.62.62.7-2.7-2.72.3-2.62.7-3.02.6-2.62.72.83.02.42.82.82.62.32.53.1
Bone: cortical area0.20.31.90.50.10.40.3-0.4-0.40.1-0.30.6-1.10.3-0.40.5-0.21.40.30.60.10.4-0.80.31.1
Bone: cortical porosity1.11.22.1-1.0-1.4-1.1-1.21.11.1-1.21.1-1.00.4-1.01.1-1.0-1.3-0.4-1.2-1.0-1.3-1.0-1.4-1.3-0.6
Bone: cortical porosity1.71.82.8-1.3-1.7-1.4-1.51.41.4-1.51.3-1.30.9-1.21.3-1.3-1.5-0.8-1.5-1.3-1.7-1.2-1.6-1.5-1.0
Bone: cortical thickness0.10.21.20.1-0.5-0.1-0.30.10.0-0.50.10.1-0.6-0.10.1-0.0-0.50.9-0.10.1-0.6-0.1-1.1-0.10.5
Bone: cortical thickness0.20.31.5-0.1-0.6-0.3-0.50.30.2-0.6-0.0-0.1-0.80.00.3-0.2-0.60.7-0.4-0.1-0.8-0.4-1.2-0.30.7
Bone: cortical tissue density6.18.010.02.82.82.82.9-2.8-2.82.5-2.82.9-3.12.7-2.82.83.03.02.62.93.02.72.52.73.2
Bone: elastic displacement0.10.10.50.1-0.2-0.0-0.00.0-0.0-0.3-0.10.1-0.70.20.00.0-0.10.4-0.10.1-0.2-0.0-0.50.10.7
Bone: elastic work0.10.10.5-0.1-0.5-0.2-0.30.20.2-0.40.0-0.1-0.30.10.2-0.2-0.30.2-0.3-0.1-0.6-0.2-0.7-0.20.3
Bone: endosteal estimation0.10.20.50.40.70.50.6-0.5-0.40.7-0.20.3-0.40.2-0.50.40.10.10.40.30.70.40.50.40.2
Bone: endosteal perimeter0.51.01.71.01.31.11.0-1.1-1.01.2-0.61.0-0.70.6-1.11.00.70.91.11.01.31.00.81.10.8
Bone: final force0.10.21.30.0-0.4-0.1-0.20.10.1-0.30.40.1-0.5-0.30.1-0.0-0.70.8-0.20.1-0.4-0.1-1.1-0.20.5
Bone: final moment0.10.21.50.1-0.3-0.0-0.20.00.0-0.30.20.1-0.6-0.20.00.0-0.70.9-0.10.1-0.4-0.1-1.2-0.10.5
Bone: marrow area0.10.20.50.40.70.50.6-0.5-0.50.7-0.20.4-0.40.2-0.50.40.20.10.40.40.70.40.50.40.2
Bone: maximum diameter0.40.70.90.90.80.90.9-0.9-0.91.0-0.80.9-0.90.8-0.90.90.20.80.90.90.90.90.20.80.8
Bone: maximum force0.10.21.30.0-0.5-0.1-0.30.10.1-0.40.40.0-0.7-0.40.1-0.1-0.70.8-0.20.0-0.5-0.1-1.2-0.30.5
Bone: maximum moment0.10.21.7-0.0-0.5-0.1-0.30.10.1-0.40.40.0-0.7-0.40.1-0.1-0.80.8-0.30.0-0.6-0.2-1.3-0.30.5
Bone: minimum diameter0.40.82.21.00.70.90.8-0.9-0.90.8-0.71.0-1.40.7-0.90.90.11.50.91.00.80.9-0.20.81.2
Bone: periosteal estimation0.40.71.20.90.90.90.9-0.9-0.90.9-0.60.9-1.10.6-0.90.90.31.00.80.90.90.80.30.80.9
Bone: periosteal perimeter0.40.71.00.91.00.90.8-0.9-0.90.9-0.50.9-0.70.4-0.90.90.61.00.90.91.00.90.50.90.8
Bone: post-yield work0.50.71.50.90.70.80.8-0.9-0.90.7-0.50.9-1.20.5-0.80.90.61.20.70.90.80.80.40.61.1
Bone: stiffness0.50.93.51.00.60.90.7-0.9-0.90.6-0.51.0-1.50.5-0.90.90.51.90.81.00.60.8-0.10.81.4
Bone: tissue strength0.10.10.50.0-0.10.0-0.0-0.0-0.0-0.20.20.1-0.7-0.20.00.0-0.20.7-0.00.10.00.0-0.5-0.00.6
Bone: trabecular number0.10.10.3-0.3-0.5-0.4-0.40.40.4-0.40.4-0.30.3-0.40.4-0.4-0.4-0.1-0.5-0.3-0.4-0.4-0.5-0.50.0
Bone: trabecular spacing0.00.00.20.00.20.10.1-0.1-0.10.0-0.30.0-0.40.3-0.00.0-0.1-0.00.10.10.1-0.0-0.10.10.1
Bone: trabecular thickness0.00.00.10.2-0.00.20.2-0.2-0.20.2-0.30.2-0.00.4-0.20.20.20.20.20.20.10.20.20.20.1
Bone: trabecular tissue density0.00.00.40.00.20.00.1-0.1-0.1-0.1-0.00.1-0.6-0.0-0.00.1-0.00.30.00.10.3-0.0-0.00.10.4
Breakpoint value in progressive ratio session0.10.10.3-0.10.4-0.10.10.00.0-0.10.4-0.10.2-0.40.1-0.10.3-0.40.1-0.10.4-0.10.50.2-0.3
Distance traveled before self-admin0.20.20.70.50.50.50.4-0.5-0.50.6-0.50.4-0.00.5-0.50.50.60.00.50.40.50.50.80.3-0.0
Distance traveled after self-admin0.20.20.60.5-0.00.40.2-0.4-0.40.3-0.80.5-0.60.8-0.40.40.10.50.40.5-0.10.3-0.00.10.6
Delta time in closed arm before/after self-admin0.00.00.1-0.1-0.1-0.1-0.10.10.1-0.10.2-0.10.1-0.20.1-0.10.2-0.2-0.0-0.1-0.2-0.10.20.1-0.1
Delta time in open arm before/after self-admin1.31.21.51.11.11.11.1-1.1-1.11.2-1.11.1-1.21.1-1.11.10.81.01.11.11.11.20.81.21.2
Diff in mean of infusions in LGA sessions0.20.30.5-0.5-0.5-0.6-0.60.50.5-0.70.6-0.50.4-0.60.6-0.6-0.5-0.5-0.6-0.5-0.4-0.5-0.5-0.4-0.2
Extinction: sum of active levers before priming0.10.10.4-0.0-0.1-0.0-0.10.10.10.00.3-0.00.5-0.30.0-0.0-0.1-0.60.1-0.1-0.1-0.00.10.3-0.6
Active lever presses in extinction session 61.01.01.51.01.01.01.1-1.0-1.00.9-0.91.0-0.80.9-1.01.01.20.81.01.01.11.01.20.90.8
Delta distance traveled before/after self-admin1.01.12.4-1.0-1.3-1.1-1.11.11.0-1.30.8-0.90.5-0.81.1-1.0-1.3-0.5-1.1-0.9-1.3-1.1-1.5-1.0-0.5
Delta ambulatory time before/after self-admin0.20.20.8-0.4-0.6-0.4-0.40.40.4-0.70.1-0.3-0.1-0.20.4-0.4-0.60.2-0.6-0.3-0.6-0.4-0.9-0.50.2
Time in closed arm before self-admin1.51.72.5-1.4-1.3-1.3-1.31.31.4-1.11.2-1.41.5-1.31.3-1.4-1.0-1.6-1.3-1.4-1.3-1.4-0.7-1.5-1.3
Time in closed arm after self-admin0.80.81.1-0.9-0.9-0.9-1.00.90.9-0.81.0-1.01.0-1.00.9-0.9-0.1-1.0-0.7-1.0-1.0-1.0-0.1-0.9-0.8
Time in open arm before self-admin3.94.14.82.11.92.12.0-2.1-2.11.9-2.22.1-2.22.2-2.12.11.82.22.02.12.02.11.51.92.0
Time in open arm after self-admin3.23.54.92.01.62.01.8-2.0-2.01.9-2.02.0-2.22.0-2.02.01.22.01.82.01.62.00.91.92.0
Sum of active levers in priming session hrs 5-60.80.81.0-0.9-0.8-0.9-0.80.90.9-1.01.0-0.90.7-1.00.9-0.9-0.9-0.8-1.0-0.9-0.7-0.8-0.7-0.9-0.8
Time to tail flick, vehicle, before self-admin1.11.12.01.01.21.01.1-1.0-1.01.0-1.01.0-0.91.0-1.01.01.41.01.01.01.01.11.30.90.9
Time to tail flick, vehicle, after self-admin0.70.71.0-0.9-0.6-0.9-0.80.90.9-1.01.0-0.90.8-1.00.9-0.9-0.8-0.7-0.9-0.9-0.7-1.0-0.8-0.6-0.7
Time to tail flick, test, before self-admin0.00.00.20.20.30.2-0.0-0.1-0.10.20.00.10.20.0-0.20.10.4-0.10.00.10.10.20.40.2-0.3
Time to tail flick, test, after self-admin1.51.52.41.21.31.21.1-1.2-1.21.0-1.11.2-1.61.1-1.21.21.31.41.21.21.21.20.91.31.5
Delta time to tail flick, vehicle, before/after SA1.41.32.2-1.1-1.1-1.1-1.11.11.1-1.21.2-1.10.8-1.21.1-1.1-1.5-0.8-1.3-1.1-1.1-1.3-1.5-1.0-0.8
Delta time to tail flick, test, before/after SA1.00.91.90.90.80.80.9-0.9-0.90.7-0.80.9-1.40.8-0.80.90.81.21.00.90.90.80.40.91.4
Ambulatory time before self-admin0.30.31.20.50.40.50.5-0.5-0.50.7-0.40.4-0.10.4-0.50.50.8-0.00.70.40.60.51.10.50.1
Ambulatory time after self-admin0.20.20.5-0.3-0.7-0.4-0.50.40.4-0.40.0-0.30.4-0.10.4-0.3-0.5-0.3-0.4-0.3-0.7-0.4-0.6-0.7-0.3
Total heroin consumption0.50.71.00.91.00.80.8-0.9-0.90.7-0.60.9-0.90.6-0.80.80.50.90.60.90.91.00.50.70.8
Area under the delay curve0.40.40.80.60.60.60.6-0.6-0.60.9-0.50.5-0.70.4-0.70.60.50.20.60.50.60.80.80.60.7
Delay disc. indifference point, 0s delay0.10.10.30.30.30.30.2-0.3-0.30.4-0.40.3-0.50.5-0.30.30.20.30.40.30.10.30.10.30.4
Delay disc. indifference point, 16s delay0.40.51.00.60.50.70.6-0.7-0.70.9-0.60.6-0.50.5-0.70.70.80.20.60.60.71.01.00.70.5
Delay disc. indifference point, 2s delay0.10.10.20.30.30.30.2-0.3-0.30.4-0.20.3-0.10.3-0.30.3-0.0-0.10.40.20.10.30.10.30.0
Delay disc. indifference point, 24s delay0.60.61.00.80.80.80.6-0.8-0.80.9-0.60.7-0.80.5-0.80.81.00.50.80.70.41.00.81.01.0
Delay disc. indifference point, 4s delay1.01.01.51.01.01.01.1-1.0-1.01.2-1.00.9-1.20.9-1.01.01.00.71.00.91.11.11.10.91.1
Delay disc. indifference point, 8s delay0.20.20.50.40.30.40.4-0.5-0.40.7-0.20.3-0.70.2-0.50.40.20.00.40.30.50.50.40.40.6
Delay discount exponential model param0.50.50.9-0.7-0.7-0.8-0.70.80.7-1.00.5-0.70.8-0.50.8-0.8-0.6-0.3-0.7-0.7-0.7-0.9-0.8-0.8-0.9
Delay discount hyperbolic model param0.40.40.7-0.6-0.6-0.6-0.60.60.6-0.90.5-0.60.7-0.40.7-0.6-0.5-0.2-0.6-0.6-0.6-0.8-0.7-0.7-0.7
Fecal boli incidents, locomotor time 10.10.10.7-0.0-0.10.0-0.00.00.00.4-0.0-0.10.40.0-0.0-0.00.1-0.90.1-0.1-0.20.00.4-0.0-0.5
Change in fecal boli incidents, locomotor task0.10.10.30.30.10.30.4-0.3-0.30.3-0.50.3-0.40.4-0.30.30.40.30.30.30.40.40.50.10.2
Time >=10cm from walls, locomotor time 10.10.10.2-0.4-0.4-0.4-0.30.40.4-0.30.4-0.40.3-0.50.4-0.4-0.1-0.4-0.4-0.4-0.3-0.30.0-0.40.0
Bouts of movement, locomotor time 10.30.41.0-0.7-0.5-0.6-0.50.60.6-0.50.8-0.70.6-1.00.6-0.6-0.4-1.0-0.5-0.7-0.3-0.50.0-0.5-0.5
Total resting periods, locomotor time 10.40.41.0-0.7-0.6-0.7-0.50.70.7-0.60.8-0.70.6-1.00.7-0.7-0.5-1.0-0.6-0.7-0.3-0.6-0.1-0.5-0.6
Rest time, locomotor task time 11.21.31.91.21.11.11.0-1.1-1.11.2-1.31.1-1.21.1-1.11.11.11.11.31.10.61.00.81.21.4
Distance moved, locomotor task time 12.12.33.4-1.5-1.5-1.5-1.41.51.5-1.61.6-1.51.7-1.61.5-1.5-1.6-1.4-1.6-1.5-1.3-1.4-1.3-1.4-1.8
Vertical activity count, locomotor time 10.00.00.2-0.1-0.4-0.2-0.20.20.2-0.30.2-0.10.1-0.10.2-0.1-0.40.1-0.3-0.1-0.1-0.1-0.5-0.1-0.3
Time >=10cm from walls, locomotor time 20.00.00.30.0-0.3-0.1-0.10.10.0-0.20.20.0-0.3-0.10.1-0.00.00.5-0.10.0-0.3-0.1-0.30.10.4
Bouts of movement, locomotor time 23.03.24.91.91.41.81.8-1.8-1.81.8-1.71.9-1.91.6-1.81.91.51.71.91.91.71.91.32.02.2
Total resting periods, locomotor time 22.93.15.01.91.31.81.7-1.8-1.81.8-1.71.8-1.81.6-1.81.81.41.71.81.81.61.81.22.02.2
Rest time, locomotor task time 21.51.83.21.31.41.31.3-1.3-1.31.2-1.31.3-1.71.4-1.31.31.31.41.31.31.31.21.01.11.8
Distance moved, locomotor task time 22.63.04.2-1.7-1.8-1.7-1.81.71.7-1.81.9-1.61.8-1.81.7-1.7-1.9-1.5-1.7-1.7-1.8-1.6-1.7-1.5-2.1
Vertical activity count, locomotor time 20.50.61.5-0.6-1.0-0.7-0.90.70.7-0.90.7-0.50.7-0.60.7-0.6-0.9-0.1-0.7-0.6-1.2-0.6-1.2-0.5-0.8
Weight adjusted by age0.20.20.60.30.30.30.4-0.3-0.30.3-0.20.2-0.70.3-0.30.30.60.40.30.30.70.20.7-0.00.7
Seeking ratio, delayed vs. immediate footshock0.70.81.90.71.20.81.0-0.8-0.80.8-1.00.7-0.40.9-0.80.81.40.60.90.81.30.71.40.50.7
Locomotion in novel chamber6.78.39.32.93.12.92.9-3.0-3.02.8-2.93.0-2.93.0-2.92.92.82.72.93.03.02.92.52.62.8
Locomotion in novel chamber post-restriction0.30.40.70.60.80.60.7-0.6-0.60.7-0.60.6-0.40.5-0.60.60.30.20.50.60.80.70.60.60.5
Progressive ratio0.50.50.80.70.80.80.8-0.8-0.80.7-0.90.8-0.70.8-0.80.70.60.50.70.80.80.70.60.90.5
Food seeking constrained by brief footshock0.50.62.50.80.60.70.6-0.7-0.80.5-0.60.9-0.70.6-0.70.80.91.60.80.90.80.70.40.80.9
Seeking ratio, punishment vs. effort0.30.40.7-0.6-0.8-0.7-0.70.60.6-0.90.7-0.50.5-0.60.7-0.6-0.40.3-0.6-0.5-0.7-0.6-0.8-0.7-0.1
Run reversals in cocaine runway, females1.01.01.4-1.1-0.9-1.1-1.01.01.1-1.11.0-1.10.7-0.91.1-1.1-1.1-0.8-1.1-1.1-0.8-1.2-1.0-0.9-0.9
Run reversals in cocaine runway, males0.30.30.90.60.50.50.6-0.5-0.60.4-0.30.6-0.70.3-0.50.50.70.90.40.60.60.50.40.30.7
Latency to leave start box in cocaine runway0.40.51.1-0.6-0.7-0.6-0.70.60.6-0.60.4-0.60.5-0.40.6-0.6-1.0-0.5-0.8-0.6-0.9-0.6-1.1-0.8-0.3
Latency to leave start box in cocaine runway, F0.30.30.6-0.5-0.6-0.5-0.50.50.5-0.40.5-0.60.7-0.50.5-0.5-0.7-0.7-0.7-0.6-0.6-0.5-0.5-0.7-0.4
Latency to leave start box in cocaine runway, M0.40.41.5-0.5-0.7-0.6-0.70.60.6-0.60.3-0.50.3-0.20.6-0.6-1.0-0.1-0.4-0.5-1.0-0.6-1.2-0.4-0.1
Cd content in liver2.12.33.31.51.61.61.7-1.6-1.51.7-1.71.5-0.81.8-1.61.61.60.71.61.51.71.51.81.60.8
Co content in liver0.60.71.00.90.90.90.9-0.9-0.90.9-0.90.9-0.30.8-0.90.90.90.50.90.90.91.00.91.00.5
Cu content in liver0.20.20.7-0.5-0.5-0.4-0.40.40.4-0.20.3-0.50.4-0.20.4-0.4-0.6-0.9-0.4-0.5-0.4-0.3-0.3-0.5-0.5
Fe content in liver0.10.10.3-0.3-0.3-0.3-0.30.30.3-0.30.4-0.30.1-0.40.3-0.3-0.5-0.1-0.4-0.3-0.3-0.3-0.6-0.3-0.0
K content in liver0.10.10.30.20.20.20.2-0.2-0.20.2-0.20.20.00.1-0.20.20.4-0.00.30.20.30.30.60.3-0.0
Mg content in liver0.10.10.60.30.30.30.4-0.3-0.30.4-0.30.30.00.2-0.30.30.5-0.20.40.30.40.40.80.4-0.2
Mn content in liver1.11.21.9-1.1-1.1-1.2-1.21.11.1-1.41.2-1.10.5-1.11.2-1.1-1.2-0.5-1.1-1.0-1.1-1.2-1.4-1.2-0.7
Na content in liver0.00.00.1-0.2-0.2-0.2-0.20.20.2-0.2-0.0-0.20.1-0.10.2-0.2-0.1-0.3-0.2-0.2-0.1-0.3-0.0-0.3-0.1
Rb content in liver0.60.71.00.90.80.90.9-0.9-0.90.9-0.70.9-0.80.6-0.90.90.80.90.90.90.91.00.71.00.9
Se content in liver0.70.91.60.91.10.91.0-0.9-0.91.1-1.00.8-0.71.0-0.90.91.20.61.00.91.10.91.20.90.6
Sr content in liver1.21.11.81.01.21.01.0-1.0-1.01.1-1.01.0-0.71.0-1.01.01.30.91.11.01.10.91.21.10.9
Zn content in liver0.91.01.31.01.01.01.1-1.0-1.01.1-1.11.0-0.41.1-1.01.01.00.51.11.01.01.11.11.10.3