Acot11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability ENSRNOG00000007837 0.12 0.07 2.1e-06 0.09 0.07 0.03 0.07 2.7e-05 1.9e-04 1.0e-02 2.0e-04
2 Brain gene expression ENSRNOG00000007837 0.13 0.07 9.3e-09 0.1 0.09 0.09 0.1 2.1e-09 8.0e-09 8.3e-09 2.6e-09
3 Brain mRNA stability ENSRNOG00000007837 0.14 0.06 5.6e-17 0.16 0.18 0.17 0.17 1.4e-14 1.5e-16 1.1e-15 7.1e-16
4 LHb mRNA stability ENSRNOG00000007837 0.29 0.12 1.1e-05 0.14 0.2 0.19 0.19 4.1e-04 1.7e-05 2.6e-05 2.4e-05
5 NAcc gene expression ENSRNOG00000007837 0.06 0.04 3.8e-04 0.01 0.03 0.03 0.02 5.7e-02 4.9e-03 5.0e-03 2.0e-02
6 NAcc mRNA stability ENSRNOG00000007837 0.15 0.08 3.7e-10 0.1 0.1 0.11 0.11 7.3e-08 8.0e-08 2.2e-08 1.9e-08
7 OFC mRNA stability ENSRNOG00000007837 0.16 0.09 9.8e-03 0.05 -0 0.01 0.03 2.6e-02 3.7e-01 1.4e-01 7.1e-02
8 PL mRNA stability ENSRNOG00000007837 0.06 0.05 1.1e-03 0.04 0.01 0.01 0.03 3.7e-04 9.9e-02 7.4e-02 1.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.41.32.1-1.4-0.6-1.4-1.2-0.9-1.3-1.3-0.5
BMI without tail0.20.40.60.6-0.00.60.70.70.80.70.3
Body weight0.20.91.6-1.30.2-1.2-0.7-0.4-1.2-1.2-0.6
Epididymis fat weight0.40.92.60.41.30.60.91.20.40.51.6
Glucose0.10.21.00.3-1.00.1-0.3-0.40.50.3-0.2
Heart weight1.11.61.9-1.2-1.0-1.3-1.3-1.4-1.3-1.3-1.2
Left kidney weight7.822.428.5-4.7-3.7-5.3-5.3-5.3-4.8-4.8-3.5
Right kidney weight4.512.817.6-3.8-2.4-4.2-4.0-3.8-3.9-3.9-2.1
Tail length0.51.42.11.20.81.41.41.31.31.2-0.1
Length with tail0.00.10.60.10.30.10.30.20.1-0.0-0.8
Length without tail0.40.81.4-1.10.5-1.0-0.6-0.5-1.1-1.2-0.9
Liver weight, left0.91.41.8-1.2-1.0-1.4-1.3-1.2-1.2-1.2-1.1
Liver weight, right0.20.32.0-0.3-0.2-0.3-0.2-0.3-0.3-0.2-1.4
Parametrial fat weight0.20.40.70.60.40.60.70.50.60.6-0.8
Retroperitoneal fat weight0.31.11.90.90.91.01.01.21.00.81.4
Intraocular pressure0.10.20.9-0.20.90.10.20.4-0.1-0.20.6
Extensor digitorum longus weight1.35.18.1-1.8-2.2-2.2-2.4-2.6-1.9-1.8-2.8
Soleus weight2.98.511.7-2.7-2.8-2.9-3.4-3.4-2.7-2.8-2.2
Tibialis anterior weight3.110.814.1-3.7-2.0-3.8-3.6-3.3-3.6-3.7-2.3
Tibia length0.10.21.1-0.11.10.00.40.5-0.1-0.2-0.1
Number of licking bursts0.30.40.7-0.80.6-0.6-0.4-0.2-0.8-0.80.5
Food consumed during 24 hour testing period0.30.31.5-0.40.5-0.20.10.5-0.4-0.41.2
Times rat made contact with spout0.40.50.7-0.7-0.5-0.8-0.8-0.8-0.7-0.7-0.6
Mean time between licks in bursts0.91.32.11.30.01.21.11.11.51.31.0
Mean num. licks in bursts0.40.51.8-0.1-1.1-0.2-0.5-0.8-0.0-0.1-1.3
Std. dev. time between licks in bursts2.42.85.61.60.91.61.61.81.71.62.4
Water consumed over 24 hours1.31.54.2-0.4-1.8-0.7-1.1-1.5-0.4-0.4-2.0
Indifference point 0 sec0.00.10.2-0.0-0.4-0.1-0.3-0.30.1-0.3-0.1
Indifference point AUC0.20.20.90.1-1.0-0.1-0.4-0.50.00.2-0.4
Indifference point function ln k0.10.20.6-0.40.1-0.4-0.2-0.3-0.3-0.5-0.8
Indifference point function log k0.10.20.6-0.40.1-0.4-0.2-0.3-0.3-0.5-0.8
Delay discounting total patch changes 0 sec0.00.00.10.2-0.30.1-0.1-0.10.3-0.1-0.2
Delay discounting total patch changes 12 sec1.52.02.91.60.51.61.51.51.71.51.0
Delay discounting total patch changes 18 sec0.30.41.2-0.1-1.1-0.2-0.5-0.7-0.1-0.0-1.1
Delay discounting total patch changes 24 sec0.20.20.4-0.5-0.2-0.5-0.6-0.5-0.5-0.60.2
Delay discounting total patch changes 6 sec0.00.10.1-0.1-0.3-0.2-0.4-0.3-0.0-0.20.0
Delay discounting time to switch 0 sec2.53.85.41.71.82.02.22.31.81.71.8
Delay discounting water rate 0 sec2.03.24.2-1.8-1.3-2.0-2.0-2.0-1.8-1.9-1.2
Delay discounting water rate 12 sec3.75.67.8-2.5-1.8-2.8-2.8-2.6-2.5-2.5-1.0
Delay discounting water rate 18 sec0.30.52.7-0.10.8-0.10.20.5-0.1-0.21.6
Delay discounting water rate 24 sec0.10.10.2-0.40.2-0.4-0.3-0.2-0.3-0.4-0.1
Delay discounting water rate 6 sec0.91.32.2-1.40.0-1.4-1.1-0.9-1.5-1.40.2
Locomotor activity0.30.51.80.0-1.4-0.2-0.7-0.90.1-0.1-0.7
Locomotor testing distance1.32.17.7-0.2-2.8-0.7-1.5-2.0-0.2-0.4-1.5
Locomotor testing rearing0.60.94.00.2-2.0-0.2-0.8-1.20.3-0.1-1.1
Light reinforcement 10.20.30.7-0.5-0.2-0.6-0.5-0.5-0.6-0.6-0.8
Light reinforcement 21.41.92.6-1.6-0.8-1.6-1.6-1.5-1.4-1.6-0.7
Reaction time number correct0.10.10.10.20.30.30.30.30.20.2-0.3
Reaction time mean minus median0.60.81.70.60.90.81.01.20.50.71.3
Reaction time mean minus median AUC0.20.30.50.50.40.60.70.60.40.60.1
Reaction time num false alarms0.81.12.0-1.3-0.1-1.3-1.0-0.7-1.2-1.4-0.1
Reaction time num false alarms AUC1.21.73.0-1.6-0.4-1.6-1.3-1.1-1.5-1.7-0.6
Reaction time trials correct on left0.10.10.10.20.30.30.30.30.20.2-0.3
Reaction time trials on left0.10.10.20.20.40.30.40.30.20.2-0.3
Reaction time mean1.52.04.60.72.11.11.51.80.60.81.8
Reaction time mean AUC1.31.73.20.91.81.11.51.60.81.01.5
Median of all reaction times1.82.45.90.82.41.21.72.00.80.91.9
Reaction time omissions0.60.93.60.21.90.51.11.30.10.20.2
Reaction time false alarm rate1.52.13.2-1.6-0.8-1.7-1.6-1.4-1.6-1.8-0.5
Reaction time premature initiation rate0.10.20.40.6-0.50.50.20.10.60.50.1
Reaction time premature initiations0.30.40.80.9-0.20.80.60.40.90.80.1
Std. dev. reaction times0.50.71.60.50.90.60.91.10.40.61.3
Reaction time trials completed0.10.10.20.20.40.30.40.30.20.2-0.3
Reaction time trials AUC0.00.00.10.10.20.10.20.20.10.1-0.4
Social response proportion1.11.24.60.90.60.90.91.01.00.82.1
Social responses0.60.71.11.00.10.90.80.81.00.91.0
Social time0.60.71.3-0.7-0.7-0.9-0.8-0.9-0.8-0.9-1.1
Conditioned locomotion0.10.10.2-0.4-0.1-0.4-0.3-0.1-0.3-0.40.4
Cocaine response after cond. corrected1.61.83.8-1.2-0.9-1.3-1.2-1.4-1.3-1.2-2.0
Cocaine response after cond. not corrected2.42.77.4-1.4-1.1-1.4-1.4-1.7-1.5-1.4-2.7
Cocaine response before conditioning0.10.20.7-0.2-0.4-0.1-0.3-0.5-0.2-0.2-0.8
Saline control response0.30.42.30.4-0.80.2-0.0-0.30.50.3-1.5
Condit. Reinf. active minus inactive responses1.11.33.5-0.6-1.9-0.8-1.2-1.4-0.5-0.6-1.4
Condit. Reinf. active-inactive response ratio1.01.04.30.0-2.1-0.2-0.8-1.10.10.1-1.4
Condit. Reinf. active responses1.11.52.8-0.8-1.7-1.0-1.3-1.5-0.8-0.9-1.5
Condit. Reinf. inactive responses0.80.91.5-1.1-0.3-1.1-1.0-1.0-1.2-1.2-0.5
Condit. Reinf. lever presses0.20.30.80.60.00.60.50.60.60.60.9
Condit. Reinf. lever reinforcers received0.81.11.9-0.8-1.4-0.9-1.1-1.2-0.8-0.9-1.0
Pavlov. Cond. lever latency0.30.42.0-0.3-0.3-0.4-0.3-0.5-0.3-0.3-1.4
Pavlov. Cond. magazine entry latency1.11.31.91.3-0.31.31.01.01.31.41.1
Pavlov. Cond. change in total contacts0.30.41.50.40.40.60.60.80.40.41.2
Pavlov. Cond. index score0.60.81.70.90.01.00.80.91.01.01.3
Pavlov. Cond. latency score0.50.61.50.7-0.00.80.60.70.80.81.2
Pavlov. Cond. lever contacts0.10.20.80.30.00.40.30.40.30.30.9
Pavlov. Cond. magazine entry number1.31.62.1-1.3-0.3-1.5-1.3-1.4-1.4-1.4-1.2
Pavlov. Cond. intertrial magazine entries0.10.10.40.10.60.10.30.40.30.00.3
Pavlov. Cond. lever-magazine prob. diff.0.81.01.61.00.01.10.90.91.11.11.3
Pavlov. Cond. response bias0.70.92.20.90.31.00.81.00.90.91.5
Conditioned reinforcement - actives2.02.02.6-1.5-1.1-1.6-1.6-1.5-1.4-1.5-0.9
Conditioned reinforcement - inactives0.20.30.5-0.70.0-0.6-0.4-0.3-0.6-0.7-0.6
Conditioned locomotion0.60.72.9-0.3-1.7-0.5-0.9-1.1-0.1-0.3-0.7
Intermittent access intake day 1-15 change0.30.30.6-0.5-0.2-0.6-0.8-0.7-0.7-0.50.4
Intermittent access intake escalation0.60.61.2-0.7-0.6-0.8-1.1-1.0-0.9-0.70.3
Intermittent access intake escalation 20.20.21.00.40.20.40.20.30.30.41.0
Intermitt. access day 1 inactive lever presses2.93.15.9-1.4-1.4-1.7-1.8-2.1-1.7-1.4-2.4
Intermitt. access day 15 inactive lever presses0.30.42.0-0.5-0.0-0.4-0.2-0.3-0.5-0.5-1.4
Intermitt. access escalation Index0.30.31.4-0.30.7-0.2-0.00.2-0.4-0.31.2
Intermittent access day 1 total infusions0.20.20.5-0.7-0.0-0.6-0.3-0.1-0.5-0.7-0.2
Intermittent access day 15 total infusions0.70.81.1-1.0-0.5-1.0-1.1-0.8-1.1-1.00.2
Intermittent access terminal intake (last 3 days)0.20.20.4-0.5-0.5-0.5-0.6-0.5-0.4-0.50.2
Intermittent access total infusions0.20.20.4-0.6-0.2-0.6-0.5-0.3-0.5-0.60.1
Intermittent access day 1 locomotion0.20.20.4-0.60.2-0.4-0.2-0.0-0.5-0.6-0.3
Intermittent access day 15 total locomotion0.00.00.20.00.00.10.10.20.10.00.5
Intermittent access total locomotion0.10.10.1-0.40.3-0.2-0.10.1-0.3-0.40.1
Intermittent access standard deviation2.72.94.3-1.8-1.4-2.0-2.1-1.8-1.8-1.8-0.0
Cocaine induced anxiety0.00.10.10.2-0.30.20.10.00.30.2-0.3
Post-drug Anxiety0.20.20.40.6-0.10.60.40.30.60.6-0.1
Baseline Anxiety0.30.40.6-0.6-0.0-0.7-0.6-0.7-0.8-0.6-0.5
Lifetime Intake0.20.30.5-0.7-0.2-0.6-0.5-0.4-0.6-0.7-0.2
Incentive Sensitization - Responses0.40.41.7-0.11.30.30.60.9-0.1-0.10.8
Incentive Sensitization - Breakpoint0.30.31.0-0.21.00.20.40.7-0.1-0.20.7
Progressive ratio test 1 active lever presses0.10.10.2-0.50.1-0.4-0.2-0.0-0.4-0.5-0.1
Progressive ratio test 1 breakpoint0.20.20.3-0.6-0.0-0.5-0.3-0.2-0.5-0.6-0.3
Progressive ratio test 1 inactive lever presses0.80.91.8-0.8-0.8-0.9-0.9-1.0-0.8-0.8-1.4
Progressive ratio test 2 active lever presses0.70.71.2-1.1-0.5-1.0-0.9-0.7-1.0-1.1-0.2
Progressive ratio test 2 breakpoint0.40.40.8-0.9-0.2-0.7-0.6-0.4-0.8-0.9-0.1
Progressive ratio test 2 inactive lever presses0.91.11.8-1.3-0.3-1.2-1.1-0.8-1.2-1.3-0.3
Total sessions with >9 infusions0.70.71.50.60.80.80.91.10.70.61.2
Short access day 1 total inactive lever presses4.24.76.3-2.4-1.1-2.5-2.4-2.2-2.5-2.4-1.0
Short access day 10 total inactive lever presses2.93.25.3-1.6-1.2-1.8-1.8-2.0-1.8-1.6-2.3
Short access day 1 total infusions0.20.20.7-0.50.9-0.20.10.2-0.4-0.5-0.5
Short access day 10 total infusions0.20.30.5-0.7-0.1-0.6-0.4-0.2-0.6-0.70.2
Short access total infusions0.20.20.3-0.60.3-0.4-0.2-0.1-0.5-0.6-0.5
Short access day 1 locomotion0.40.40.6-0.8-0.3-0.7-0.7-0.5-0.7-0.80.2
Short access day 10 total locomotion0.60.71.2-1.1-0.1-1.0-0.8-0.6-1.1-1.1-0.3
Short access total locomotion0.00.00.2-0.1-0.5-0.1-0.2-0.10.0-0.10.1
Compulsive drug intake0.60.63.10.60.30.70.70.30.50.6-1.8
One hour access (0.3 mA shock)0.40.50.70.60.50.80.70.80.70.60.8
One hour access (shock baseline)0.30.31.7-0.3-0.5-0.4-0.5-0.2-0.3-0.31.3
Number of responses in last shaping day1.51.51.9-1.3-0.8-1.4-1.3-1.2-1.2-1.3-1.2
Context. condit. distance diff. score0.60.72.80.4-1.40.1-0.2-0.60.40.5-1.7
Locomotion velocity, session 11.31.41.81.20.71.31.31.31.31.31.0
Locomotion distance, session 10.00.00.00.00.2-0.00.10.1-0.0-0.0-0.2
Locomotion velocity, session 20.81.01.21.00.61.11.11.11.11.10.7
Locomotion distance, session 20.40.61.0-1.0-0.1-1.0-0.8-0.6-1.0-1.0-0.1
Locomotion velocity, session 30.00.00.1-0.10.0-0.00.20.30.10.10.3
Locomotion distance, session 30.20.20.4-0.2-0.6-0.3-0.4-0.5-0.1-0.2-0.6
Stereotopy head waving bouts, day 30.30.30.9-0.61.0-0.30.10.4-0.5-0.50.6
Stereotopy head waving duration, day 30.20.20.6-0.30.8-0.20.20.4-0.3-0.30.6
Locomotion velocity, session 70.50.61.6-0.4-1.2-0.7-0.9-1.0-0.4-0.4-0.5
Locomotion distance, session 71.01.34.6-0.2-2.2-0.6-1.1-1.4-0.1-0.2-1.4
Stereotopy head waving bouts, day 71.01.22.20.71.41.01.31.50.80.80.9
Stereotopy head waving duration, day 71.72.03.70.91.81.21.61.91.01.01.5
Locomotion velocity, session 80.60.81.20.90.10.90.80.91.11.00.9
Locomotion distance, session 80.61.03.1-0.4-1.4-0.7-0.8-1.0-0.3-0.4-1.8
Degree of sensitization distance0.70.71.8-0.4-1.4-0.7-1.0-1.1-0.5-0.4-0.9
Degree of sensitization stereotypy1.01.12.10.61.50.91.21.40.70.70.9
Condit. Reinf. active minus inactive responses0.70.81.9-0.6-1.0-0.7-0.9-1.0-0.5-0.6-1.4
Condit. Reinf. active-inactive response ratio1.31.43.2-0.9-1.3-0.9-1.1-1.3-0.8-0.9-1.8
Condit. Reinf. active responses0.40.50.9-0.9-0.2-0.8-0.7-0.7-0.8-0.9-0.5
Condit. Reinf. inactive responses0.50.62.10.11.30.20.50.70.1-0.01.4
Incentive salience index mean1.41.63.0-1.2-1.0-1.2-1.3-1.4-1.1-1.3-1.7
Condit. Reinf. lever presses0.91.21.5-1.1-0.7-1.1-1.1-1.1-1.0-1.2-1.2
Time in familiar zone, hab. session 10.60.62.4-0.2-1.5-0.4-0.8-1.0-0.1-0.1-0.5
Time in novel zone, hab. session 10.70.71.40.90.20.90.80.40.80.9-1.2
Total zone transitions, hab. session 10.00.00.10.10.0-0.00.10.10.0-0.0-0.3
Total locomotion distance, hab. session 10.40.50.8-0.8-0.4-0.9-0.8-0.7-0.9-0.8-0.4
Locomotion velocity, hab. session 10.20.20.5-0.50.5-0.4-0.10.1-0.5-0.50.7
Time in familiar zone, hab. session 20.40.42.20.2-1.5-0.1-0.6-0.70.20.1-0.1
Time in novel zone, hab. session 20.20.20.30.30.50.40.60.40.30.4-0.6
Total zone transitions, hab. session 20.10.10.2-0.2-0.3-0.4-0.3-0.2-0.2-0.3-0.0
Total locomotion distance, hab. session 20.70.91.5-1.1-0.5-1.2-1.1-0.9-1.0-1.10.4
Locomotion velocity, hab. session 20.91.32.1-1.3-0.4-1.4-1.2-0.9-1.3-1.40.4
Novel to familiar place preference ratio0.20.20.5-0.50.1-0.5-0.5-0.4-0.5-0.70.2
Novelty place preference0.10.10.2-0.30.2-0.3-0.3-0.3-0.3-0.50.3
Time in novel zone, NPP test0.00.00.1-0.20.1-0.2-0.2-0.2-0.1-0.30.1
Total zone transitions, NPP test0.81.21.6-1.0-0.8-1.2-1.1-1.1-1.0-1.2-1.3
Total locomotion distance, NPP test1.31.82.5-1.4-0.9-1.6-1.5-1.4-1.4-1.5-0.6
Locomotion velocity, NPP test1.82.63.8-1.8-1.0-2.0-1.8-1.6-1.7-1.9-0.6
Pavlov. Cond. lever latency1.62.12.91.70.51.71.41.31.61.61.3
Pavlov. Cond. magazine entry latency0.50.61.00.80.51.00.90.80.81.0-0.3
Pavlov. Cond. change in total contacts0.10.10.3-0.20.3-0.10.10.1-0.1-0.2-0.5
Pavlov. Cond. index score0.30.30.9-0.6-0.2-0.6-0.5-0.5-0.7-0.5-0.9
Pavlov. Cond. latency score0.30.40.6-0.70.0-0.7-0.5-0.4-0.8-0.6-0.8
Pavlov. Cond. lever contacts1.21.42.0-1.4-0.3-1.4-1.1-1.1-1.4-1.3-1.0
Pavlov. Cond. magazine entry number0.20.30.5-0.4-0.5-0.6-0.7-0.6-0.4-0.60.3
Pavlov. Cond. intertrial magazine entries0.50.61.9-0.70.9-0.6-0.4-0.0-0.8-0.81.4
Pavlov. Cond. lever-magazine prob. diff.0.30.40.7-0.7-0.3-0.6-0.5-0.6-0.7-0.5-0.8
Pavlov. Cond. response bias0.30.32.0-0.3-0.3-0.2-0.2-0.4-0.3-0.1-1.4
Bone: apparent density0.20.30.60.6-0.80.40.20.10.70.6-0.4
Bone surface0.10.10.20.30.10.30.40.30.30.3-0.5
Bone volume0.10.10.3-0.2-0.3-0.3-0.2-0.2-0.2-0.2-0.5
Bone: connectivity density0.50.81.41.1-0.21.00.90.81.21.1-0.0
Bone: cortical apparent density1.31.72.71.60.21.51.31.11.51.70.8
Bone: cortical area1.01.52.1-1.4-0.7-1.4-1.3-1.2-1.4-1.4-0.8
Bone: cortical porosity0.90.94.90.02.20.41.11.0-0.1-0.0-0.5
Bone: cortical porosity1.61.77.30.42.70.91.61.70.30.40.2
Bone: cortical thickness2.43.96.0-2.4-0.8-2.5-2.2-1.8-2.3-2.4-0.3
Bone: cortical thickness1.41.74.2-1.3-0.7-1.3-1.1-1.2-1.1-1.3-2.1
Bone: cortical tissue density1.41.93.01.70.21.61.41.21.61.70.8
Bone: elastic displacement2.93.29.0-0.6-3.0-1.1-1.9-2.4-0.7-0.6-2.3
Bone: elastic work1.82.36.3-0.7-2.5-1.1-1.7-2.0-0.7-0.7-1.6
Bone: endosteal estimation0.51.04.01.0-0.50.90.60.10.80.9-2.0
Bone: endosteal perimeter0.30.71.11.00.51.11.00.80.90.9-0.4
Bone: final force0.00.00.10.10.20.10.10.1-0.00.10.3
Bone: final moment0.00.00.0-0.10.0-0.2-0.1-0.1-0.2-0.20.1
Bone: marrow area0.40.94.20.9-0.50.80.5-0.00.70.8-2.0
Bone: maximum diameter0.10.10.2-0.40.4-0.3-0.00.1-0.5-0.5-0.4
Bone: maximum force0.00.00.2-0.0-0.3-0.1-0.1-0.2-0.0-0.1-0.4
Bone: maximum moment0.10.20.3-0.2-0.5-0.4-0.4-0.5-0.2-0.3-0.6
Bone: minimum diameter0.40.82.1-0.3-1.2-0.5-0.8-1.1-0.4-0.4-1.5
Bone: periosteal estimation0.30.73.4-0.4-0.7-0.4-0.5-0.7-0.5-0.5-1.8
Bone: periosteal perimeter0.10.21.2-0.2-0.1-0.2-0.2-0.3-0.3-0.3-1.1
Bone: post-yield work0.20.30.40.60.10.60.60.50.60.5-0.5
Bone: stiffness0.10.20.70.20.80.30.60.60.20.10.1
Bone: tissue strength0.60.61.00.9-1.00.70.20.11.00.80.7
Bone: trabecular number0.50.81.51.1-0.80.80.60.21.21.1-0.8
Bone: trabecular spacing1.11.42.5-1.60.5-1.3-1.0-0.6-1.6-1.60.6
Bone: trabecular thickness0.30.40.80.8-0.70.50.40.20.90.7-0.4
Bone: trabecular tissue density0.20.31.2-0.3-0.3-0.3-0.5-0.2-0.5-0.31.1
Breakpoint value in progressive ratio session0.20.20.30.60.20.50.60.50.60.5-0.1
Distance traveled before self-admin2.32.54.7-1.1-2.2-1.4-1.8-2.0-1.0-1.0-1.7
Distance traveled after self-admin4.44.97.0-2.1-2.4-2.4-2.6-2.6-2.0-2.2-0.9
Delta time in closed arm before/after self-admin2.82.78.4-0.3-2.9-0.8-1.5-2.1-0.4-0.2-2.3
Delta time in open arm before/after self-admin1.31.22.60.71.61.01.21.40.70.61.1
Diff in mean of infusions in LGA sessions0.30.32.30.00.30.00.30.2-0.10.0-1.5
Extinction: sum of active levers before priming0.20.21.00.2-0.10.20.30.00.20.4-1.0
Active lever presses in extinction session 61.81.72.2-1.3-0.9-1.5-1.3-1.3-1.3-1.3-1.5
Delta distance traveled before/after self-admin1.11.22.2-1.40.0-1.3-1.0-0.7-1.3-1.50.5
Delta ambulatory time before/after self-admin1.01.13.1-1.10.3-1.1-0.8-0.3-1.0-1.21.8
Time in closed arm before self-admin1.01.12.10.71.30.91.11.40.90.61.4
Time in closed arm after self-admin0.10.10.20.4-0.40.30.10.10.40.40.4
Time in open arm before self-admin0.50.51.7-0.1-1.1-0.3-0.6-0.9-0.30.1-1.3
Time in open arm after self-admin0.00.10.20.00.40.10.20.1-0.00.0-0.5
Sum of active levers in priming session hrs 5-60.80.83.5-0.2-1.3-0.4-0.6-0.9-0.3-0.0-1.9
Time to tail flick, vehicle, before self-admin0.50.51.5-0.70.8-0.6-0.1-0.1-0.7-0.8-1.2
Time to tail flick, vehicle, after self-admin0.91.01.7-1.3-0.0-1.1-0.9-0.7-1.3-1.2-0.6
Time to tail flick, test, before self-admin0.70.70.9-0.8-0.6-0.8-0.9-0.9-0.9-0.8-0.7
Time to tail flick, test, after self-admin1.71.82.2-1.4-0.9-1.5-1.4-1.4-1.5-1.3-1.2
Delta time to tail flick, vehicle, before/after SA1.00.91.4-1.0-1.1-1.0-1.2-1.1-1.0-0.90.0
Delta time to tail flick, test, before/after SA0.00.00.1-0.20.2-0.10.10.1-0.1-0.1-0.1
Ambulatory time before self-admin3.33.56.8-1.1-2.6-1.5-1.9-2.3-1.0-1.0-2.6
Ambulatory time after self-admin2.93.24.5-1.8-1.8-2.0-2.1-2.1-1.6-1.7-1.0
Total heroin consumption1.82.13.21.41.11.51.71.81.41.41.2
Area under the delay curve0.90.93.90.11.30.20.61.10.20.12.0
Delay disc. indifference point, 0s delay1.01.12.40.51.30.71.01.30.70.61.6
Delay disc. indifference point, 16s delay0.70.71.5-1.20.5-1.0-0.6-0.3-1.0-1.20.5
Delay disc. indifference point, 2s delay0.50.53.10.40.30.30.30.50.40.31.8
Delay disc. indifference point, 24s delay0.40.41.60.00.90.20.40.80.00.11.2
Delay disc. indifference point, 4s delay1.11.25.60.21.30.30.71.10.10.22.4
Delay disc. indifference point, 8s delay0.20.31.2-0.10.70.00.20.50.0-0.11.1
Delay discount exponential model param0.91.04.0-0.1-1.4-0.3-0.7-1.1-0.2-0.2-2.0
Delay discount hyperbolic model param1.11.24.9-0.3-1.4-0.4-0.8-1.2-0.3-0.3-2.2
Fecal boli incidents, locomotor time 10.20.21.1-0.00.60.20.30.10.00.2-1.1
Change in fecal boli incidents, locomotor task1.00.91.41.00.90.91.11.20.70.81.1
Time >=10cm from walls, locomotor time 10.70.71.31.0-0.80.70.40.11.00.9-1.2
Bouts of movement, locomotor time 11.61.72.91.11.71.31.61.61.21.10.2
Total resting periods, locomotor time 11.61.83.71.11.91.31.71.71.11.00.2
Rest time, locomotor task time 10.50.50.80.80.50.90.80.60.80.7-0.4
Distance moved, locomotor task time 10.50.50.8-0.6-0.9-0.7-0.8-0.6-0.8-0.60.6
Vertical activity count, locomotor time 11.11.21.9-1.1-0.8-1.2-1.2-1.0-1.4-1.00.7
Time >=10cm from walls, locomotor time 20.40.41.3-0.2-1.1-0.3-0.5-0.70.1-0.2-1.2
Bouts of movement, locomotor time 20.20.20.40.40.40.30.50.60.40.30.5
Total resting periods, locomotor time 20.20.30.50.40.50.40.50.70.50.40.6
Rest time, locomotor task time 20.70.81.50.71.20.80.91.00.50.61.2
Distance moved, locomotor task time 22.32.74.9-1.4-2.2-1.6-1.8-1.9-1.4-1.4-1.2
Vertical activity count, locomotor time 23.23.65.1-1.7-2.3-2.0-2.2-2.2-1.7-1.6-1.2
Weight adjusted by age0.30.30.5-0.6-0.0-0.6-0.7-0.6-0.6-0.7-0.1
Seeking ratio, delayed vs. immediate footshock5.76.59.2-2.0-3.0-2.5-2.8-3.0-2.1-1.9-2.8
Locomotion in novel chamber1.82.23.5-1.9-0.6-1.8-1.5-1.2-1.8-1.80.1
Locomotion in novel chamber post-restriction0.60.81.3-1.1-0.0-1.1-0.8-0.4-1.1-1.10.5
Progressive ratio0.60.72.5-0.80.8-0.6-0.30.2-0.8-0.81.6
Food seeking constrained by brief footshock2.22.74.62.10.32.01.71.32.02.10.0
Seeking ratio, punishment vs. effort2.22.74.52.1-0.81.91.30.62.12.1-1.4
Run reversals in cocaine runway, females1.71.73.80.61.80.91.31.60.80.61.9
Run reversals in cocaine runway, males2.22.23.2-1.3-1.4-1.6-1.8-1.8-1.5-1.3-0.9
Latency to leave start box in cocaine runway0.50.50.8-0.9-0.0-0.8-0.6-0.5-0.9-0.9-0.8
Latency to leave start box in cocaine runway, F1.41.53.4-1.3-0.2-1.2-1.0-1.0-1.4-1.3-1.8
Latency to leave start box in cocaine runway, M0.10.10.30.30.00.20.20.20.30.30.5
Cd content in liver0.60.73.20.7-0.20.70.5-0.00.60.7-1.8
Co content in liver0.70.82.80.6-1.50.3-0.1-0.50.60.6-1.7
Cu content in liver0.40.51.90.6-1.40.2-0.4-0.70.60.6-0.4
Fe content in liver1.51.86.8-1.1-0.4-1.0-1.0-1.3-1.1-1.1-2.6
K content in liver0.50.51.00.80.10.80.50.50.80.81.0
Mg content in liver0.50.53.2-0.00.90.10.20.6-0.1-0.01.8
Mn content in liver0.10.20.70.1-0.6-0.1-0.2-0.10.10.10.9
Na content in liver0.20.30.50.6-0.20.50.40.30.70.6-0.3
Rb content in liver0.10.20.60.20.50.20.30.40.30.20.8
Se content in liver0.20.21.50.2-0.30.10.0-0.20.30.2-1.2
Sr content in liver0.40.31.4-0.0-0.8-0.1-0.3-0.6-0.1-0.0-1.2
Zn content in liver0.50.50.80.70.50.90.80.70.80.70.3