Hub : Genes

Bloc1s1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007784 0.05 0.03 4.3e-05 0.02 0.03 0.03 0.02 6.3e-03 2.0e-04 5.7e-04 1.0e-03
2 BLA gene expression ENSRNOG00000007784 0.13 0.08 7.4e-07 0.11 0.1 0.1 0.09 2.4e-06 4.6e-06 3.4e-06 1.3e-05
3 Brain isoform ratio ENSRNOT00000010380 0.11 0.07 1.6e-07 0.08 0.07 0.07 0.08 4.4e-08 2.5e-07 2.0e-07 1.4e-07
4 Eye intron excision ratio chr7:1348296:1350200 0.36 0.19 3.2e-03 0.2 0.13 0.13 0.17 5.9e-04 5.3e-03 5.6e-03 1.5e-03
5 Liver isoform ratio ENSRNOT00000010380 0.15 0.1 5.5e-11 0.07 0.08 0.08 0.08 2.1e-08 3.5e-09 2.4e-09 3.2e-09
6 Liver isoform ratio ENSRNOT00000081756 0.33 0.15 0.0e+00 0.23 0.24 0.24 0.24 5.1e-25 4.4e-26 2.2e-26 2.1e-26
7 NAcc alternative TSS ENSRNOT00000099202 0.03 0.03 1.0e-02 0.01 0.01 0.01 0.01 2.9e-02 4.5e-02 4.6e-02 5.1e-02
8 NAcc alternative TSS ENSRNOT00000105370 0.04 0.03 7.8e-03 0.01 0.01 0.02 0.01 2.4e-02 2.8e-02 1.6e-02 3.7e-02
9 NAcc gene expression ENSRNOG00000007784 0.07 0.05 3.9e-04 0.04 0.02 0.03 0.04 5.7e-04 6.8e-03 3.2e-03 1.1e-03
10 OFC gene expression ENSRNOG00000007784 0.19 0.12 4.5e-03 0.09 0.06 0.04 0.07 3.8e-03 1.4e-02 3.7e-02 1.1e-02
11 PL gene expression ENSRNOG00000007784 0.11 0.07 3.5e-07 0.06 0.07 0.07 0.07 2.2e-05 4.1e-06 9.6e-06 7.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail7.423.927.5-3.5-4.8-4.8-5.2-5.25.2-4.74.7-5.2-5.0-5.2
BMI without tail1.53.13.9-1.7-2.0-2.0-1.7-1.81.7-1.91.6-1.7-1.6-1.8
Body weight1.56.38.0-1.9-2.6-2.5-2.7-2.62.3-2.62.8-2.4-2.5-2.6
Epididymis fat weight0.10.10.4-0.2-0.00.10.40.3-0.6-0.00.20.60.40.3
Glucose2.13.23.6-1.4-1.9-1.8-1.7-1.91.7-1.91.9-1.7-1.8-1.9
Heart weight0.00.00.1-0.4-0.2-0.00.20.10.1-0.2-0.00.00.30.1
Left kidney weight0.10.40.90.90.20.3-0.8-0.50.70.20.4-0.9-0.9-0.6
Right kidney weight0.41.12.01.31.21.40.80.9-0.51.3-1.10.50.80.8
Tail length4.212.616.81.83.13.14.03.9-4.13.1-3.34.14.04.0
Length with tail1.34.96.61.72.12.32.32.4-2.62.1-1.72.52.22.4
Length without tail0.20.30.70.5-0.10.1-0.8-0.50.6-0.10.7-0.7-0.8-0.6
Liver weight, left1.32.12.7-1.4-1.6-1.6-1.3-1.51.6-1.61.2-1.5-1.2-1.5
Liver weight, right0.71.22.1-0.7-1.1-0.9-1.0-1.31.3-1.00.8-1.4-1.1-1.3
Parametrial fat weight0.10.10.3-0.10.10.20.40.3-0.30.1-0.40.40.50.4
Retroperitoneal fat weight2.37.88.8-2.5-3.0-2.9-2.7-2.92.9-2.92.6-2.7-2.6-2.9
Intraocular pressure0.30.51.3-0.8-0.2-0.20.80.6-1.1-0.2-0.01.10.80.7
Extensor digitorum longus weight5.522.126.5-4.3-5.0-5.1-4.6-4.94.5-5.04.6-4.4-4.4-4.8
Soleus weight6.719.522.1-3.2-4.3-4.5-4.6-4.74.4-4.44.5-4.4-4.6-4.7
Tibialis anterior weight1.34.65.6-1.4-2.1-2.1-2.4-2.32.1-2.12.3-2.1-2.3-2.3
Tibia length0.82.44.00.81.31.41.61.7-2.01.3-1.11.91.71.7
Number of licking bursts3.74.35.9-2.2-2.4-2.4-1.8-2.01.8-2.32.2-1.7-1.9-2.0
Food consumed during 24 hour testing period0.40.50.7-0.4-0.7-0.6-0.8-0.70.7-0.60.6-0.8-0.7-0.8
Times rat made contact with spout1.21.42.0-1.4-1.4-1.4-1.0-1.11.0-1.41.2-1.0-0.9-1.1
Mean time between licks in bursts1.01.42.10.41.00.91.41.4-1.11.2-1.41.21.51.4
Mean num. licks in bursts0.81.01.31.01.11.10.91.0-0.91.0-1.00.80.91.0
Std. dev. time between licks in bursts1.01.12.51.61.31.20.80.9-0.41.5-1.40.30.70.8
Water consumed over 24 hours0.70.81.60.3-0.3-0.3-1.1-1.01.2-0.40.6-1.3-1.1-1.1
Indifference point 0 sec3.15.07.6-1.3-1.9-2.0-2.4-2.52.8-1.91.7-2.8-2.3-2.5
Indifference point AUC0.40.40.90.40.50.60.60.8-0.90.5-0.10.90.70.7
Indifference point function ln k0.10.10.3-0.3-0.2-0.2-0.0-0.30.6-0.2-0.3-0.6-0.1-0.3
Indifference point function log k0.10.10.3-0.3-0.2-0.2-0.0-0.30.6-0.2-0.3-0.6-0.1-0.3
Delay discounting total patch changes 0 sec2.84.56.9-1.3-1.9-2.0-2.2-2.42.6-1.91.6-2.6-2.1-2.3
Delay discounting total patch changes 12 sec1.72.32.9-1.6-1.7-1.7-1.4-1.51.5-1.71.5-1.3-1.3-1.5
Delay discounting total patch changes 18 sec0.10.10.3-0.2-0.3-0.3-0.2-0.30.1-0.40.5-0.1-0.2-0.2
Delay discounting total patch changes 24 sec0.70.81.2-0.3-0.7-0.7-1.1-1.00.9-0.91.1-0.9-1.1-1.0
Delay discounting total patch changes 6 sec1.62.43.8-1.0-1.4-1.4-1.6-1.71.9-1.41.1-1.9-1.6-1.7
Delay discounting time to switch 0 sec0.30.41.10.3-0.1-0.2-1.1-0.70.6-0.30.6-0.7-1.0-0.7
Delay discounting water rate 0 sec0.50.82.0-1.4-1.3-1.2-0.3-0.80.8-1.10.6-0.6-0.3-0.7
Delay discounting water rate 12 sec0.81.22.7-1.6-1.5-1.4-0.4-1.00.9-1.40.7-0.8-0.5-0.9
Delay discounting water rate 18 sec0.50.73.2-1.8-0.9-0.90.90.2-0.4-0.8-0.20.50.90.3
Delay discounting water rate 24 sec2.02.88.9-3.0-2.4-2.4-0.3-1.20.8-2.31.3-0.5-0.4-1.0
Delay discounting water rate 6 sec0.71.12.7-0.70.20.21.60.9-0.80.2-1.31.11.61.1
Locomotor activity3.04.76.32.32.52.51.92.2-2.22.4-2.01.91.82.1
Locomotor testing distance1.32.12.81.51.71.71.31.4-1.41.6-1.51.11.21.4
Locomotor testing rearing0.00.00.1-0.4-0.2-0.30.1-0.0-0.2-0.20.10.10.0-0.0
Light reinforcement 13.97.29.22.02.82.82.92.7-2.52.6-3.02.42.82.8
Light reinforcement 21.21.62.30.91.31.31.41.3-1.11.2-1.51.21.31.3
Reaction time number correct1.21.83.2-1.7-1.7-1.7-0.9-1.20.9-1.81.5-0.8-0.9-1.2
Reaction time mean minus median1.31.71.91.11.31.21.21.4-1.31.4-1.21.41.21.4
Reaction time mean minus median AUC1.51.94.42.11.71.70.71.3-1.11.8-1.11.00.81.1
Reaction time num false alarms0.50.70.9-0.8-0.9-1.0-0.9-0.90.9-0.90.7-0.8-0.8-0.9
Reaction time num false alarms AUC0.60.91.4-1.2-1.1-1.2-0.8-0.90.9-1.10.7-0.8-0.8-0.9
Reaction time trials correct on left1.21.83.2-1.7-1.7-1.7-0.9-1.20.9-1.81.5-0.8-0.9-1.2
Reaction time trials on left1.21.72.9-1.6-1.6-1.6-0.9-1.20.9-1.71.4-0.8-0.9-1.1
Reaction time mean1.01.42.71.61.41.40.71.2-1.11.5-0.71.10.71.1
Reaction time mean AUC0.50.71.81.31.01.00.30.8-0.61.1-0.40.70.30.6
Median of all reaction times0.50.71.71.31.01.00.40.8-0.71.0-0.30.80.40.7
Reaction time omissions0.10.10.20.50.40.20.10.10.10.4-0.4-0.1-0.10.1
Reaction time false alarm rate0.10.10.3-0.1-0.2-0.3-0.5-0.40.5-0.10.2-0.4-0.5-0.4
Reaction time premature initiation rate1.31.73.00.00.70.81.71.4-1.70.8-1.11.61.71.5
Reaction time premature initiations0.60.81.7-0.9-0.2-0.11.30.8-1.2-0.1-0.41.21.20.9
Std. dev. reaction times0.91.21.81.31.31.20.71.1-0.91.4-1.00.90.81.0
Reaction time trials completed1.21.72.9-1.6-1.6-1.6-0.9-1.20.9-1.71.4-0.8-0.9-1.1
Reaction time trials AUC1.42.03.6-1.8-1.8-1.8-0.9-1.30.9-1.91.5-0.8-0.9-1.2
Social response proportion0.50.61.10.90.80.90.60.8-1.10.7-0.20.80.50.7
Social responses8.210.612.83.13.53.62.93.4-3.43.4-2.93.23.03.3
Social time1.51.92.9-1.2-1.5-1.5-1.2-1.41.2-1.61.7-1.1-1.4-1.4
Conditioned locomotion1.41.73.5-1.9-1.7-1.8-0.7-1.10.7-1.71.5-0.6-0.8-1.0
Cocaine response after cond. corrected2.52.74.5-2.1-2.1-2.0-1.2-1.51.3-2.01.7-1.2-1.2-1.4
Cocaine response after cond. not corrected2.42.75.0-2.2-2.0-2.0-1.1-1.51.3-2.01.5-1.2-1.1-1.4
Cocaine response before conditioning0.70.81.50.91.11.00.80.8-0.70.9-1.20.60.80.9
Saline control response0.50.60.9-0.8-0.8-1.0-0.8-0.80.6-0.90.6-0.7-0.7-0.7
Condit. Reinf. active minus inactive responses2.42.94.70.41.41.42.21.8-1.81.4-2.01.82.11.9
Condit. Reinf. active-inactive response ratio0.70.81.7-0.80.10.11.30.9-1.10.0-0.51.21.20.9
Condit. Reinf. active responses2.02.74.81.01.61.61.81.7-1.41.7-2.21.31.81.7
Condit. Reinf. inactive responses0.60.81.71.11.11.10.50.7-0.41.1-1.30.30.60.7
Condit. Reinf. lever presses3.04.15.70.91.81.72.22.2-2.21.8-2.32.12.42.2
Condit. Reinf. lever reinforcers received1.42.03.50.61.31.31.61.5-1.31.3-1.91.21.71.5
Pavlov. Cond. lever latency1.52.02.4-1.1-1.4-1.4-1.3-1.51.6-1.51.4-1.4-1.5-1.5
Pavlov. Cond. magazine entry latency2.52.83.21.41.81.71.51.8-1.71.8-1.71.71.71.8
Pavlov. Cond. change in total contacts0.91.32.20.71.11.11.11.2-1.01.1-1.50.91.31.2
Pavlov. Cond. index score2.22.93.51.21.71.71.61.8-1.71.7-1.91.61.81.8
Pavlov. Cond. latency score2.22.83.21.41.71.71.51.8-1.71.7-1.71.61.71.8
Pavlov. Cond. lever contacts1.31.92.40.81.31.21.41.5-1.51.3-1.51.41.51.5
Pavlov. Cond. magazine entry number2.42.93.3-1.4-1.8-1.8-1.6-1.81.6-1.81.8-1.6-1.7-1.8
Pavlov. Cond. intertrial magazine entries1.01.21.8-1.3-1.3-1.3-0.9-1.11.0-1.30.9-1.0-0.9-1.0
Pavlov. Cond. lever-magazine prob. diff.2.43.13.91.31.81.81.71.9-1.71.8-2.01.61.91.9
Pavlov. Cond. response bias2.33.13.91.01.71.51.81.9-1.91.7-1.91.82.01.9
Conditioned reinforcement - actives0.70.72.51.01.11.00.30.40.21.1-1.6-0.30.50.4
Conditioned reinforcement - inactives0.60.71.8-1.3-0.8-0.9-0.1-0.71.1-0.9-0.6-1.00.0-0.5
Conditioned locomotion4.85.712.31.82.52.62.52.3-1.62.5-3.51.52.62.3
Intermittent access intake day 1-15 change1.21.24.40.31.00.81.50.9-0.40.9-2.10.41.41.0
Intermittent access intake escalation0.90.92.7-0.60.30.11.50.7-0.40.2-1.70.51.50.9
Intermittent access intake escalation 21.31.33.2-0.30.60.41.81.1-0.90.6-1.71.01.71.2
Intermitt. access day 1 inactive lever presses0.50.61.8-0.70.00.01.20.6-0.40.0-1.30.51.30.7
Intermitt. access day 15 inactive lever presses1.31.43.1-0.00.70.61.71.2-1.10.8-1.61.21.71.3
Intermitt. access escalation Index0.90.81.91.41.31.10.10.30.31.3-1.3-0.40.20.3
Intermittent access day 1 total infusions0.30.30.7-0.0-0.2-0.3-0.8-0.60.8-0.20.3-0.8-0.7-0.6
Intermittent access day 15 total infusions0.10.10.8-0.30.1-0.10.2-0.10.50.1-0.9-0.40.3-0.0
Intermittent access terminal intake (last 3 days)0.20.20.80.30.40.2-0.0-0.20.70.4-0.9-0.8-0.0-0.1
Intermittent access total infusions0.20.20.6-0.3-0.2-0.4-0.4-0.50.8-0.2-0.2-0.8-0.3-0.5
Intermittent access day 1 locomotion0.00.00.0-0.1-0.1-0.0-0.1-0.0-0.0-0.00.10.0-0.0-0.0
Intermittent access day 15 total locomotion1.21.34.40.41.01.01.41.0-0.50.9-2.10.51.51.1
Intermittent access total locomotion0.40.51.00.50.80.70.60.6-0.50.7-1.00.40.70.7
Intermittent access standard deviation0.70.82.80.10.60.61.30.7-0.30.7-1.70.31.20.8
Cocaine induced anxiety1.41.63.11.81.51.50.81.2-1.21.5-0.91.10.81.1
Post-drug Anxiety0.60.62.91.71.11.1-0.20.4-0.21.1-0.30.1-0.20.2
Baseline Anxiety0.00.00.2-0.4-0.3-0.30.0-0.10.0-0.30.0-0.00.1-0.0
Lifetime Intake0.60.62.0-0.2-0.3-0.5-0.8-0.91.4-0.3-0.2-1.4-0.7-0.9
Incentive Sensitization - Responses0.40.41.10.40.70.50.60.5-0.20.7-1.00.20.60.5
Incentive Sensitization - Breakpoint0.50.51.40.70.90.70.70.6-0.30.9-1.20.20.70.6
Progressive ratio test 1 active lever presses0.91.01.8-0.8-0.8-0.9-1.1-1.11.3-0.80.4-1.3-0.9-1.1
Progressive ratio test 1 breakpoint1.01.12.0-0.7-0.8-0.9-1.2-1.11.4-0.80.4-1.4-1.0-1.1
Progressive ratio test 1 inactive lever presses0.70.84.10.50.80.80.80.40.30.9-2.0-0.40.90.5
Progressive ratio test 2 active lever presses0.30.30.9-0.2-0.2-0.3-0.5-0.61.0-0.1-0.4-1.0-0.3-0.5
Progressive ratio test 2 breakpoint0.20.20.70.50.40.3-0.2-0.20.70.5-0.8-0.8-0.1-0.2
Progressive ratio test 2 inactive lever presses0.20.31.00.30.30.2-0.2-0.30.80.4-1.0-0.9-0.0-0.2
Total sessions with >9 infusions0.70.82.11.10.90.8-0.3-0.21.11.0-1.5-1.3-0.2-0.2
Short access day 1 total inactive lever presses0.20.21.20.20.30.40.30.10.30.4-1.1-0.30.40.2
Short access day 10 total inactive lever presses0.30.31.4-0.6-0.0-0.00.90.3-0.0-0.0-1.20.10.90.4
Short access day 1 total infusions0.90.93.10.80.40.5-0.7-0.71.60.6-1.1-1.8-0.6-0.6
Short access day 10 total infusions0.40.41.4-0.2-0.2-0.3-0.7-0.71.2-0.2-0.4-1.2-0.5-0.7
Short access total infusions1.11.24.20.2-0.2-0.2-1.2-1.21.9-0.1-0.3-2.0-1.1-1.2
Short access day 1 locomotion0.60.61.81.01.01.00.20.50.11.0-1.3-0.20.50.4
Short access day 10 total locomotion3.13.37.50.61.51.52.31.8-1.41.5-2.71.42.41.9
Short access total locomotion0.70.72.40.81.01.00.70.7-0.21.0-1.60.20.90.7
Compulsive drug intake0.40.40.8-0.4-0.7-0.6-0.8-0.70.5-0.70.9-0.5-0.7-0.6
One hour access (0.3 mA shock)0.30.40.6-0.5-0.5-0.6-0.6-0.70.8-0.60.3-0.8-0.5-0.6
One hour access (shock baseline)0.10.10.5-0.4-0.0-0.20.4-0.00.3-0.0-0.7-0.20.40.1
Number of responses in last shaping day2.22.36.01.01.51.51.71.4-0.81.6-2.40.81.71.4
Context. condit. distance diff. score0.20.30.4-0.5-0.6-0.6-0.4-0.60.5-0.60.6-0.5-0.5-0.5
Locomotion velocity, session 10.30.40.80.7-0.10.0-0.9-0.50.40.00.7-0.6-0.9-0.7
Locomotion distance, session 10.30.42.21.50.81.0-0.10.3-0.10.9-0.3-0.1-0.10.1
Locomotion velocity, session 21.72.05.02.21.81.90.81.1-0.71.9-1.40.60.71.0
Locomotion distance, session 22.23.16.32.52.12.21.01.7-1.62.2-1.21.51.11.5
Locomotion velocity, session 34.55.26.51.62.22.22.42.5-2.52.2-2.02.52.32.5
Locomotion distance, session 30.00.00.2-0.10.10.00.20.2-0.40.1-0.00.40.20.3
Stereotopy head waving bouts, day 36.37.58.62.42.92.92.62.8-2.62.9-2.92.52.72.8
Stereotopy head waving duration, day 34.96.08.92.02.62.62.42.5-2.02.6-3.01.92.52.5
Locomotion velocity, session 70.10.10.30.60.40.50.30.2-0.10.4-0.20.10.10.2
Locomotion distance, session 70.10.20.7-0.8-0.6-0.50.0-0.20.1-0.60.40.0-0.0-0.1
Stereotopy head waving bouts, day 70.80.92.31.51.21.20.50.8-0.81.2-0.80.60.40.7
Stereotopy head waving duration, day 70.60.72.51.61.11.20.20.7-0.71.1-0.50.50.20.5
Locomotion velocity, session 81.11.34.12.01.41.50.30.9-0.91.5-0.50.70.30.8
Locomotion distance, session 80.20.30.60.80.60.60.30.6-0.60.6-0.10.60.30.5
Degree of sensitization distance0.50.50.7-0.5-0.8-0.6-0.7-0.80.8-0.70.8-0.8-0.7-0.8
Degree of sensitization stereotypy0.30.30.70.4-0.2-0.1-0.8-0.50.4-0.20.7-0.5-0.9-0.6
Condit. Reinf. active minus inactive responses2.22.52.91.31.61.61.71.6-1.41.6-1.61.51.61.6
Condit. Reinf. active-inactive response ratio0.50.50.90.10.60.51.00.7-0.60.5-0.90.60.90.8
Condit. Reinf. active responses3.13.84.92.12.22.21.82.0-1.62.2-1.91.61.71.9
Condit. Reinf. inactive responses1.41.73.41.81.61.60.91.2-1.11.6-1.01.00.81.1
Incentive salience index mean1.31.62.51.61.51.51.11.2-1.01.5-1.11.00.91.2
Condit. Reinf. lever presses0.40.52.81.70.90.9-0.30.2-0.20.90.20.1-0.40.1
Time in familiar zone, hab. session 14.64.36.21.01.81.82.32.3-2.51.8-1.72.52.32.3
Time in novel zone, hab. session 13.23.15.3-0.2-1.2-1.2-2.2-2.02.2-1.21.4-2.3-2.1-2.0
Total zone transitions, hab. session 10.40.62.41.51.01.10.10.6-0.51.1-0.30.40.10.5
Total locomotion distance, hab. session 11.92.77.32.72.12.20.81.4-1.12.1-1.30.90.81.2
Locomotion velocity, hab. session 11.92.75.92.42.02.11.01.5-1.32.1-1.41.11.01.4
Time in familiar zone, hab. session 25.05.27.20.92.01.82.72.5-2.51.9-2.32.62.72.6
Time in novel zone, hab. session 25.35.37.6-0.7-1.9-1.8-2.7-2.52.7-1.82.2-2.8-2.7-2.7
Total zone transitions, hab. session 20.60.81.70.8-0.2-0.1-1.2-0.91.0-0.10.8-1.2-1.3-1.0
Total locomotion distance, hab. session 20.30.41.61.30.70.80.10.4-0.40.8-0.10.30.00.3
Locomotion velocity, hab. session 20.40.52.41.60.90.9-0.00.4-0.40.9-0.10.3-0.10.3
Novel to familiar place preference ratio2.72.94.6-0.1-1.2-1.1-2.1-1.92.0-1.11.6-2.1-2.2-2.0
Novelty place preference1.81.83.10.1-0.9-0.8-1.7-1.51.7-0.81.2-1.7-1.7-1.6
Time in novel zone, NPP test2.22.43.9-0.1-1.1-1.0-1.9-1.71.9-1.01.4-2.0-1.9-1.8
Total zone transitions, NPP test0.50.71.40.2-0.6-0.5-1.2-0.90.7-0.51.2-0.8-1.2-1.0
Total locomotion distance, NPP test0.20.30.60.80.00.1-0.7-0.40.40.10.6-0.4-0.8-0.5
Locomotion velocity, NPP test0.10.20.90.90.30.3-0.4-0.00.00.40.4-0.1-0.5-0.2
Pavlov. Cond. lever latency0.20.21.1-1.1-0.6-0.60.2-0.1-0.0-0.5-0.10.10.30.0
Pavlov. Cond. magazine entry latency1.51.92.60.81.31.21.61.5-1.51.2-1.21.61.51.5
Pavlov. Cond. change in total contacts0.10.10.3-0.1-0.2-0.3-0.4-0.40.6-0.30.3-0.4-0.5-0.4
Pavlov. Cond. index score0.40.51.21.10.90.90.50.7-0.60.9-0.40.60.30.6
Pavlov. Cond. latency score0.50.71.91.41.11.10.40.7-0.51.0-0.50.50.30.6
Pavlov. Cond. lever contacts0.20.31.41.20.50.5-0.5-0.10.20.40.4-0.2-0.6-0.2
Pavlov. Cond. magazine entry number0.40.60.9-0.6-0.8-0.7-0.8-0.80.8-0.70.5-0.9-0.7-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.6-0.2-0.10.60.3-0.4-0.1-0.20.40.60.3
Pavlov. Cond. lever-magazine prob. diff.0.60.71.31.11.11.00.60.8-0.71.0-0.60.70.50.8
Pavlov. Cond. response bias0.60.71.10.70.80.80.90.9-1.00.8-0.41.00.70.9
Bone: apparent density0.61.04.02.01.21.1-0.9-0.10.61.1-0.4-0.9-0.7-0.3
Bone surface1.52.710.83.32.32.2-0.50.40.52.2-1.6-0.9-0.30.2
Bone volume1.42.49.73.12.02.0-0.90.10.71.9-1.2-1.2-0.6-0.1
Bone: connectivity density0.40.62.41.60.90.9-0.6-0.00.40.9-0.5-0.6-0.4-0.1
Bone: cortical apparent density1.21.62.4-1.0-1.2-1.2-1.3-1.41.5-1.20.9-1.5-1.3-1.3
Bone: cortical area0.71.13.10.6-0.1-0.1-1.3-1.11.6-0.10.2-1.8-1.3-1.2
Bone: cortical porosity0.20.20.60.80.70.70.20.20.10.6-0.8-0.20.20.2
Bone: cortical porosity0.20.30.70.80.50.4-0.4-0.20.70.5-0.5-0.7-0.3-0.2
Bone: cortical thickness1.11.83.7-0.3-0.8-0.8-1.5-1.61.9-0.90.8-1.9-1.6-1.5
Bone: cortical thickness0.91.01.4-1.1-1.2-1.1-0.8-1.00.9-1.21.1-0.9-0.9-1.0
Bone: cortical tissue density0.91.21.7-0.9-1.0-1.1-1.1-1.21.3-1.00.8-1.2-1.1-1.1
Bone: elastic displacement0.00.00.10.30.20.10.20.10.00.2-0.2-0.00.10.1
Bone: elastic work0.60.81.4-0.0-0.6-0.6-1.1-1.01.1-0.50.8-1.1-1.2-1.0
Bone: endosteal estimation0.40.92.50.1-0.4-0.5-1.1-1.11.5-0.40.3-1.6-1.1-1.1
Bone: endosteal perimeter0.51.02.41.51.41.30.50.7-0.31.4-1.30.10.50.6
Bone: final force2.43.96.7-0.4-1.3-1.2-2.5-2.22.4-1.31.7-2.6-2.5-2.3
Bone: final moment2.23.76.4-0.3-1.2-1.2-2.5-2.22.4-1.21.6-2.5-2.4-2.2
Bone: marrow area0.40.82.20.1-0.4-0.5-1.0-1.01.4-0.40.3-1.5-1.0-1.0
Bone: maximum diameter0.71.33.51.91.61.60.50.7-0.11.6-1.5-0.00.50.7
Bone: maximum force2.54.37.3-0.6-1.4-1.4-2.6-2.32.6-1.51.7-2.7-2.5-2.4
Bone: maximum moment2.44.17.2-0.5-1.4-1.4-2.5-2.32.5-1.41.6-2.7-2.5-2.3
Bone: minimum diameter0.20.41.20.70.30.3-0.7-0.51.00.2-0.2-1.1-0.6-0.5
Bone: periosteal estimation0.81.64.30.6-0.2-0.2-1.5-1.41.9-0.30.4-2.1-1.6-1.4
Bone: periosteal perimeter0.30.51.91.40.90.9-0.3-0.00.60.9-0.7-0.7-0.3-0.1
Bone: post-yield work0.30.40.6-0.4-0.5-0.5-0.6-0.70.8-0.50.4-0.8-0.6-0.7
Bone: stiffness4.06.39.7-1.2-2.0-1.9-2.9-2.83.0-2.02.2-3.1-2.9-2.8
Bone: tissue strength3.73.65.4-1.0-1.6-1.6-2.1-2.12.3-1.61.6-2.3-2.1-2.1
Bone: trabecular number0.91.44.12.01.61.60.20.9-0.71.6-1.00.40.40.7
Bone: trabecular spacing0.81.05.0-2.2-1.4-1.30.5-0.3-0.0-1.40.50.30.4-0.1
Bone: trabecular thickness1.31.66.52.61.31.3-1.2-0.41.01.3-0.4-1.4-1.1-0.6
Bone: trabecular tissue density5.57.69.1-2.7-3.0-3.0-2.6-2.92.9-2.92.3-2.8-2.5-2.8
Breakpoint value in progressive ratio session2.12.34.10.61.21.22.01.6-1.71.2-1.51.71.91.7
Distance traveled before self-admin0.80.81.00.81.00.90.91.0-1.00.8-0.70.90.91.0
Distance traveled after self-admin0.30.30.60.70.80.70.40.5-0.40.7-0.80.30.50.5
Delta time in closed arm before/after self-admin1.11.04.4-2.1-1.4-1.40.1-0.60.5-1.40.3-0.30.1-0.4
Delta time in open arm before/after self-admin2.32.25.0-0.7-1.2-1.3-1.8-1.51.2-1.42.2-1.2-1.8-1.6
Diff in mean of infusions in LGA sessions2.42.73.61.01.51.51.91.7-1.61.5-1.81.61.91.7
Extinction: sum of active levers before priming2.42.55.10.20.90.91.91.8-2.10.9-1.02.31.91.8
Active lever presses in extinction session 60.80.81.20.90.90.90.81.0-1.10.9-0.51.10.70.9
Delta distance traveled before/after self-admin0.00.00.10.20.10.1-0.2-0.10.20.2-0.4-0.3-0.1-0.1
Delta ambulatory time before/after self-admin0.10.10.30.50.20.2-0.3-0.10.40.3-0.2-0.4-0.4-0.2
Time in closed arm before self-admin0.30.41.00.70.00.0-1.0-0.50.60.10.6-0.7-1.0-0.6
Time in closed arm after self-admin0.10.20.5-0.2-0.2-0.2-0.2-0.40.7-0.1-0.6-0.7-0.2-0.3
Time in open arm before self-admin1.11.24.20.20.80.81.41.0-0.50.9-2.00.51.41.1
Time in open arm after self-admin1.31.42.3-1.2-1.3-1.3-1.1-1.21.0-1.31.5-0.9-1.1-1.2
Sum of active levers in priming session hrs 5-60.30.30.40.20.40.40.60.6-0.60.4-0.40.60.60.6
Time to tail flick, vehicle, before self-admin2.82.85.12.22.12.11.31.4-0.82.1-2.30.61.21.3
Time to tail flick, vehicle, after self-admin0.30.30.7-0.4-0.0-0.00.60.5-0.70.0-0.20.80.70.6
Time to tail flick, test, before self-admin1.31.32.91.71.41.50.51.0-0.61.6-1.30.60.60.8
Time to tail flick, test, after self-admin0.30.31.21.10.70.7-0.00.20.00.8-0.7-0.1-0.00.2
Delta time to tail flick, vehicle, before/after SA2.52.45.0-2.1-2.0-2.0-1.1-1.10.4-2.02.2-0.2-1.0-1.1
Delta time to tail flick, test, before/after SA0.20.10.3-0.6-0.3-0.30.40.1-0.5-0.40.40.50.20.2
Ambulatory time before self-admin0.20.20.40.30.40.50.60.5-0.60.4-0.30.50.60.5
Ambulatory time after self-admin0.10.10.20.40.40.40.20.2-0.10.3-0.40.00.20.2
Total heroin consumption2.02.43.01.41.61.61.51.7-1.71.6-1.21.71.41.6
Area under the delay curve0.20.21.00.1-0.3-0.4-0.6-0.40.1-0.41.0-0.2-0.7-0.5
Delay disc. indifference point, 0s delay2.02.24.50.4-0.7-0.8-2.1-1.51.4-0.81.9-1.6-2.1-1.7
Delay disc. indifference point, 16s delay0.10.10.30.40.40.30.40.3-0.60.30.10.50.20.3
Delay disc. indifference point, 2s delay0.50.61.20.1-0.7-0.5-1.0-0.70.5-0.51.1-0.6-1.1-0.8
Delay disc. indifference point, 24s delay0.80.72.2-0.4-0.7-0.8-0.9-0.80.4-0.91.5-0.4-1.0-0.9
Delay disc. indifference point, 4s delay0.30.31.21.10.70.7-0.00.4-0.50.7-0.20.30.10.3
Delay disc. indifference point, 8s delay0.40.41.0-0.8-0.6-0.8-0.5-0.50.0-0.81.0-0.0-0.4-0.4
Delay discount exponential model param0.20.21.0-0.10.30.30.50.30.00.3-1.00.10.60.4
Delay discount hyperbolic model param0.30.41.2-0.00.50.50.70.5-0.20.5-1.10.30.80.6
Fecal boli incidents, locomotor time 11.11.22.3-1.5-1.5-1.4-0.7-0.90.5-1.41.3-0.4-0.7-0.9
Change in fecal boli incidents, locomotor task0.80.72.31.51.21.10.30.6-0.31.1-0.70.30.30.5
Time >=10cm from walls, locomotor time 10.60.61.10.3-0.3-0.3-1.1-0.80.9-0.30.6-1.1-1.1-0.9
Bouts of movement, locomotor time 10.50.60.70.40.80.70.80.8-0.80.7-0.80.70.90.8
Total resting periods, locomotor time 11.11.21.50.81.11.11.11.2-1.21.1-1.11.11.11.2
Rest time, locomotor task time 10.40.40.50.70.70.70.40.7-0.70.7-0.40.60.50.6
Distance moved, locomotor task time 10.50.61.30.4-0.2-0.2-0.9-0.81.2-0.20.4-1.1-1.0-0.9
Vertical activity count, locomotor time 10.80.81.6-0.8-0.8-0.9-0.7-1.01.3-0.90.4-1.2-0.7-0.9
Time >=10cm from walls, locomotor time 21.01.11.5-1.1-1.2-1.1-0.8-1.11.0-1.10.8-1.0-0.8-1.0
Bouts of movement, locomotor time 20.40.51.41.21.10.90.20.4-0.40.9-0.60.20.20.3
Total resting periods, locomotor time 20.50.51.71.31.20.90.10.4-0.30.9-0.60.10.20.3
Rest time, locomotor task time 20.10.10.60.80.40.4-0.20.1-0.10.4-0.0-0.0-0.2-0.0
Distance moved, locomotor task time 20.10.10.6-0.8-0.4-0.40.2-0.10.1-0.40.10.00.2-0.0
Vertical activity count, locomotor time 21.41.53.1-1.8-1.4-1.5-0.8-1.21.0-1.51.1-0.9-0.8-1.0
Weight adjusted by age0.10.10.3-0.5-0.2-0.40.30.1-0.1-0.2-0.10.20.30.1
Seeking ratio, delayed vs. immediate footshock2.12.44.61.51.81.81.31.4-1.01.8-2.20.81.41.4
Locomotion in novel chamber0.10.10.3-0.3-0.2-0.3-0.2-0.40.6-0.3-0.1-0.6-0.2-0.4
Locomotion in novel chamber post-restriction3.23.84.71.31.71.92.12.1-2.21.8-1.72.12.12.1
Progressive ratio0.91.11.6-1.0-1.0-1.1-0.9-1.11.3-1.10.6-1.2-0.9-1.1
Food seeking constrained by brief footshock1.01.32.80.70.90.91.11.3-1.70.9-0.21.71.01.2
Seeking ratio, punishment vs. effort1.72.03.81.01.21.31.41.6-1.91.2-0.61.91.31.6
Run reversals in cocaine runway, females1.81.82.91.41.41.71.01.4-1.31.4-1.01.31.21.3
Run reversals in cocaine runway, males2.72.63.81.61.61.91.61.6-1.41.9-1.71.31.51.6
Latency to leave start box in cocaine runway0.40.51.31.00.40.1-1.0-0.50.60.40.2-0.8-1.1-0.6
Latency to leave start box in cocaine runway, F0.80.92.51.40.40.1-1.3-0.70.80.40.6-1.0-1.6-0.8
Latency to leave start box in cocaine runway, M0.10.10.5-0.7-0.2-0.40.20.0-0.0-0.3-0.30.10.30.1
Cd content in liver0.40.41.1-0.2-0.6-0.4-0.7-0.50.7-0.41.0-0.4-0.8-0.7
Co content in liver1.21.42.00.41.01.01.41.3-1.31.0-1.11.41.41.4
Cu content in liver0.70.92.20.3-0.4-0.3-1.0-1.01.5-0.30.5-1.5-1.1-1.1
Fe content in liver0.40.50.9-0.9-0.9-0.9-0.6-0.70.7-0.80.5-0.6-0.5-0.6
K content in liver0.80.81.81.31.21.10.50.7-0.61.2-1.20.40.60.7
Mg content in liver0.50.51.91.41.00.9-0.10.5-0.40.9-0.50.20.10.4
Mn content in liver1.21.35.52.31.61.6-0.00.5-0.11.6-1.1-0.10.00.4
Na content in liver0.20.20.40.2-0.2-0.2-0.5-0.40.3-0.20.5-0.5-0.6-0.5
Rb content in liver0.40.51.60.80.30.1-0.7-0.61.20.2-0.6-1.3-0.7-0.7
Se content in liver0.00.10.10.40.30.3-0.00.2-0.20.3-0.20.20.10.2
Sr content in liver0.40.40.9-0.70.10.11.00.5-0.50.1-0.80.50.90.7
Zn content in liver1.71.93.8-0.50.50.61.81.5-1.80.6-0.91.91.81.6