Ehd4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007584 0.07 0.04 3.9e-05 0.03 0.04 0.04 0.03 4.5e-04 7.9e-05 2.9e-05 2.2e-04
2 BLA gene expression ENSRNOG00000007584 0.32 0.11 5.6e-17 0.23 0.22 0.21 0.23 1.7e-12 4.0e-12 1.3e-11 1.4e-12
3 Brain gene expression ENSRNOG00000007584 0.32 0.11 0.0e+00 0.24 0.25 0.25 0.26 1.0e-21 2.6e-23 2.5e-23 2.1e-24
4 Brain mRNA stability ENSRNOG00000007584 0.1 0.05 5.1e-09 0.1 0.09 0.06 0.09 2.7e-09 1.6e-08 1.6e-06 8.1e-09
5 Liver gene expression ENSRNOG00000007584 0.33 0.1 0.0e+00 0.24 0.22 0.21 0.24 4.2e-26 5.0e-24 6.6e-23 3.9e-26
6 NAcc gene expression ENSRNOG00000007584 0.03 0.02 5.2e-03 0.03 0.02 0.02 0.02 4.5e-03 1.5e-02 1.8e-02 1.5e-02
7 OFC gene expression ENSRNOG00000007584 0.3 0.13 1.2e-04 0.14 0.13 0.11 0.11 4.4e-04 5.7e-04 1.5e-03 1.7e-03
8 PL gene expression ENSRNOG00000007584 0.43 0.12 0.0e+00 0.28 0.25 0.26 0.27 3.0e-21 1.1e-18 9.1e-20 1.6e-20
9 PL mRNA stability ENSRNOG00000007584 0.05 0.03 6.3e-04 0.02 0.02 0.03 0.03 6.6e-03 5.4e-03 4.3e-03 4.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail5.116.420.8-3.64.44.14.1-4.0-3.54.04.14.6
BMI without tail5.010.513.5-2.73.63.23.1-3.2-3.73.23.13.4
Body weight5.925.029.4-4.75.45.25.2-5.1-4.05.15.25.1
Epididymis fat weight0.71.72.2-1.51.31.51.5-1.4-0.61.41.40.9
Glucose0.71.11.7-0.61.01.31.2-1.2-0.81.21.20.5
Heart weight7.610.812.9-3.13.43.43.6-3.6-2.43.63.42.9
Left kidney weight2.47.012.1-3.53.12.62.7-2.5-2.12.42.62.1
Right kidney weight3.610.119.2-4.43.72.93.0-2.9-2.72.92.93.0
Tail length0.30.91.6-0.40.90.91.0-1.1-1.31.10.90.5
Length with tail1.03.64.3-1.92.12.02.0-1.9-1.61.92.01.5
Length without tail1.02.12.8-1.71.51.51.5-1.3-0.51.31.61.6
Liver weight, left3.35.410.2-1.42.62.12.1-2.0-3.22.02.22.7
Liver weight, right1.32.23.4-1.81.81.31.2-1.2-1.61.21.31.6
Parametrial fat weight0.10.20.7-0.80.60.30.3-0.3-0.40.30.40.5
Retroperitoneal fat weight4.615.319.0-3.64.04.44.3-4.2-2.14.24.33.5
Intraocular pressure1.52.24.11.1-1.5-1.5-1.41.52.0-1.5-1.4-1.1
Extensor digitorum longus weight0.20.71.0-0.80.90.80.8-0.8-0.90.80.71.0
Soleus weight0.00.10.30.5-0.30.10.1-0.10.20.10.0-0.2
Tibialis anterior weight0.20.71.3-0.10.41.11.1-1.10.01.11.00.4
Tibia length0.61.85.3-2.31.41.21.3-1.2-0.11.21.30.8
Number of licking bursts0.40.51.61.3-0.5-0.7-0.70.7-0.7-0.7-0.7-0.1
Food consumed during 24 hour testing period0.20.20.50.6-0.1-0.4-0.40.4-0.7-0.4-0.40.2
Times rat made contact with spout0.30.40.8-0.90.70.60.6-0.6-0.00.60.60.7
Mean time between licks in bursts1.11.52.11.1-1.1-1.4-1.41.40.3-1.4-1.4-0.7
Mean num. licks in bursts1.01.22.8-1.70.91.11.2-1.20.61.21.20.5
Std. dev. time between licks in bursts1.21.52.4-1.61.41.01.0-1.0-1.11.01.01.5
Water consumed over 24 hours0.10.10.50.3-0.20.10.1-0.10.70.10.1-0.2
Indifference point 0 sec1.93.17.5-2.71.81.71.8-1.50.61.51.71.8
Indifference point AUC2.83.24.51.8-2.1-1.8-1.61.51.9-1.5-1.8-2.1
Indifference point function ln k4.15.87.5-2.02.72.42.3-2.2-2.62.22.42.7
Indifference point function log k4.15.87.5-2.02.72.42.3-2.2-2.62.22.42.7
Delay discounting total patch changes 0 sec1.62.66.0-2.51.61.51.7-1.40.61.41.61.7
Delay discounting total patch changes 12 sec0.40.53.4-0.6-0.30.10.2-0.31.80.30.1-0.6
Delay discounting total patch changes 18 sec0.60.83.50.4-1.0-0.6-0.40.51.9-0.5-0.7-1.0
Delay discounting total patch changes 24 sec0.91.22.2-1.51.30.81.1-1.0-0.51.00.81.5
Delay discounting total patch changes 6 sec0.30.42.8-0.3-0.4-0.10.10.11.7-0.1-0.1-0.7
Delay discounting time to switch 0 sec0.30.41.90.2-0.7-0.5-0.50.41.4-0.4-0.4-0.8
Delay discounting water rate 0 sec0.91.41.8-0.71.11.41.3-1.3-0.81.31.31.2
Delay discounting water rate 12 sec0.30.42.30.90.20.10.2-0.1-1.50.10.20.5
Delay discounting water rate 18 sec0.60.73.6-0.10.90.50.4-0.4-1.90.30.51.1
Delay discounting water rate 24 sec0.60.81.40.30.61.01.0-1.1-0.61.11.20.9
Delay discounting water rate 6 sec0.50.73.11.8-0.9-0.5-0.60.6-0.0-0.6-0.5-0.6
Locomotor activity0.20.30.60.2-0.4-0.6-0.80.70.4-0.7-0.7-0.4
Locomotor testing distance0.50.91.10.4-0.8-1.0-1.11.01.0-1.0-0.9-1.0
Locomotor testing rearing1.11.72.51.2-1.5-1.1-1.31.21.5-1.2-1.1-1.6
Light reinforcement 11.73.25.4-2.31.11.81.9-1.92.11.81.90.2
Light reinforcement 20.91.13.40.6-1.2-0.8-0.80.71.9-0.7-0.7-1.5
Reaction time number correct3.44.96.0-1.42.32.32.4-2.2-2.42.22.32.2
Reaction time mean minus median0.91.21.5-1.21.21.11.0-1.2-0.71.21.11.1
Reaction time mean minus median AUC3.03.85.0-2.02.12.01.8-2.2-1.22.22.01.8
Reaction time num false alarms0.00.10.2-0.2-0.20.00.2-0.00.5-0.0-0.1-0.4
Reaction time num false alarms AUC0.10.10.40.2-0.5-0.2-0.00.10.7-0.1-0.3-0.6
Reaction time trials correct on left3.44.96.0-1.42.32.32.4-2.2-2.42.22.32.2
Reaction time trials on left3.54.96.0-1.52.32.32.5-2.3-2.32.22.32.2
Reaction time mean0.50.71.11.0-1.0-0.7-0.60.61.0-0.6-0.6-1.0
Reaction time mean AUC0.20.20.50.6-0.6-0.4-0.40.30.7-0.3-0.3-0.5
Median of all reaction times1.82.53.51.8-1.9-1.4-1.31.41.7-1.4-1.4-1.8
Reaction time omissions0.40.51.4-1.20.60.70.7-0.70.50.70.70.0
Reaction time false alarm rate1.01.52.70.7-1.4-1.1-1.11.11.6-1.1-1.2-1.4
Reaction time premature initiation rate0.81.03.70.5-1.1-0.8-0.60.71.9-0.7-0.6-1.3
Reaction time premature initiations0.20.20.5-0.30.10.40.7-0.50.60.50.6-0.1
Std. dev. reaction times0.70.91.2-1.01.01.00.9-1.1-0.21.11.00.9
Reaction time trials completed3.54.96.0-1.52.32.32.5-2.3-2.32.22.32.2
Reaction time trials AUC3.34.76.1-1.32.22.32.5-2.3-2.22.22.32.1
Social response proportion1.11.22.0-0.40.21.21.4-1.21.11.21.4-0.7
Social responses1.11.46.70.8-1.3-0.00.20.02.6-0.1-0.1-1.8
Social time0.10.10.10.3-0.10.30.3-0.30.30.30.30.3
Conditioned locomotion2.83.33.8-1.71.91.91.9-1.9-1.61.91.91.4
Cocaine response after cond. corrected2.12.34.12.0-1.3-1.7-1.71.7-0.4-1.7-1.8-0.5
Cocaine response after cond. not corrected2.93.24.52.1-1.5-2.0-2.12.1-0.5-2.1-2.1-0.6
Cocaine response before conditioning0.10.10.2-0.3-0.3-0.4-0.40.40.5-0.4-0.4-0.4
Saline control response3.14.16.2-2.51.92.22.2-2.20.02.22.21.5
Condit. Reinf. active minus inactive responses1.41.82.7-1.01.11.61.6-1.6-0.21.61.60.9
Condit. Reinf. active-inactive response ratio0.91.01.5-0.60.81.21.2-1.2-0.21.21.20.6
Condit. Reinf. active responses2.02.84.2-1.31.32.02.0-2.00.02.02.11.0
Condit. Reinf. inactive responses1.31.62.3-1.21.01.41.5-1.50.51.51.50.6
Condit. Reinf. lever presses0.91.21.5-1.20.81.21.2-1.20.81.21.20.7
Condit. Reinf. lever reinforcers received1.72.43.6-1.31.11.81.9-1.90.41.91.90.8
Pavlov. Cond. lever latency4.35.98.02.6-2.1-2.8-2.82.8-0.1-2.8-2.8-1.6
Pavlov. Cond. magazine entry latency1.71.92.8-1.10.61.61.7-1.71.41.71.60.0
Pavlov. Cond. change in total contacts1.62.23.4-1.30.91.81.9-1.90.81.91.80.3
Pavlov. Cond. index score2.83.65.5-1.61.22.32.3-2.30.92.32.30.6
Pavlov. Cond. latency score2.43.04.6-1.51.12.12.1-2.10.82.12.10.5
Pavlov. Cond. lever contacts3.24.46.0-2.21.72.42.5-2.50.62.52.41.3
Pavlov. Cond. magazine entry number1.82.33.51.2-0.8-1.8-1.91.9-0.9-1.9-1.8-0.2
Pavlov. Cond. intertrial magazine entries0.20.31.6-0.20.5-0.2-0.20.2-1.2-0.2-0.20.8
Pavlov. Cond. lever-magazine prob. diff.2.63.35.1-1.51.12.22.3-2.31.02.32.20.5
Pavlov. Cond. response bias3.75.27.5-2.21.72.72.7-2.70.82.72.71.1
Conditioned reinforcement - actives0.10.10.6-0.80.10.10.10.10.6-0.10.1-0.2
Conditioned reinforcement - inactives0.10.10.2-0.00.20.50.4-0.2-0.20.20.40.0
Conditioned locomotion0.30.31.5-1.0-0.1-0.1-0.10.31.2-0.3-0.1-0.3
Intermittent access intake day 1-15 change0.40.41.80.70.30.20.1-0.0-1.30.00.10.9
Intermittent access intake escalation0.30.31.50.90.10.10.00.1-1.2-0.10.00.6
Intermittent access intake escalation 21.01.03.31.5-0.3-0.7-0.70.8-1.8-0.9-0.70.6
Intermitt. access day 1 inactive lever presses0.70.81.8-1.30.80.91.0-0.90.20.91.00.4
Intermitt. access day 15 inactive lever presses0.10.10.5-0.0-0.20.20.3-0.30.70.30.3-0.4
Intermitt. access escalation Index0.10.10.3-0.00.00.30.3-0.40.60.40.30.3
Intermittent access day 1 total infusions0.20.31.7-0.3-0.30.10.1-0.01.30.00.1-0.6
Intermittent access day 15 total infusions0.00.00.00.2-0.10.20.2-0.00.20.00.20.0
Intermittent access terminal intake (last 3 days)0.10.10.20.40.10.20.2-0.0-0.50.00.20.3
Intermittent access total infusions0.00.00.1-0.20.10.30.3-0.10.20.20.3-0.1
Intermittent access day 1 locomotion0.80.82.4-1.50.70.80.9-0.80.80.80.90.5
Intermittent access day 15 total locomotion0.50.60.9-0.40.70.90.9-0.8-0.60.90.90.4
Intermittent access total locomotion0.10.10.1-0.40.10.30.3-0.20.30.20.3-0.1
Intermittent access standard deviation0.20.21.10.30.40.30.30.0-1.0-0.00.30.7
Cocaine induced anxiety0.60.72.4-1.50.90.80.8-0.8-0.30.80.80.3
Post-drug Anxiety0.40.40.9-0.70.80.60.6-0.5-1.00.50.60.7
Baseline Anxiety0.10.10.40.30.30.40.4-0.3-0.60.30.40.5
Lifetime Intake0.10.10.20.1-0.3-0.2-0.20.40.4-0.4-0.2-0.3
Incentive Sensitization - Responses0.10.10.10.10.10.30.3-0.40.10.40.30.1
Incentive Sensitization - Breakpoint0.10.10.20.10.10.30.3-0.40.20.40.30.1
Progressive ratio test 1 active lever presses0.20.20.8-0.1-0.10.40.4-0.20.90.20.4-0.3
Progressive ratio test 1 breakpoint0.10.10.50.1-0.20.20.2-0.10.70.00.2-0.5
Progressive ratio test 1 inactive lever presses0.30.31.50.0-0.30.20.20.01.2-0.00.2-0.9
Progressive ratio test 2 active lever presses0.30.31.30.4-0.6-0.00.00.11.2-0.10.0-1.0
Progressive ratio test 2 breakpoint0.30.31.70.2-0.40.30.3-0.31.30.30.3-0.8
Progressive ratio test 2 inactive lever presses0.20.20.4-0.30.00.50.5-0.50.60.50.5-0.3
Total sessions with >9 infusions0.20.20.5-0.7-0.1-0.3-0.30.50.7-0.5-0.3-0.3
Short access day 1 total inactive lever presses0.30.30.5-0.70.60.50.5-0.4-0.60.40.50.5
Short access day 10 total inactive lever presses1.11.21.9-1.30.91.31.2-1.4-0.61.41.2-0.1
Short access day 1 total infusions0.90.91.40.5-0.9-1.0-1.01.20.8-1.2-1.0-0.8
Short access day 10 total infusions0.10.10.5-0.70.30.30.4-0.20.30.20.40.1
Short access total infusions0.10.10.30.1-0.3-0.3-0.30.60.4-0.6-0.3-0.2
Short access day 1 locomotion0.50.51.50.1-0.7-0.5-0.50.61.2-0.6-0.5-0.9
Short access day 10 total locomotion0.30.40.80.1-0.0-0.6-0.70.7-0.9-0.7-0.70.3
Short access total locomotion0.20.21.0-1.00.30.20.2-0.00.60.00.20.1
Compulsive drug intake0.10.10.80.9-0.2-0.1-0.10.0-0.4-0.0-0.1-0.0
One hour access (0.3 mA shock)0.20.21.61.2-0.40.00.00.1-0.3-0.10.0-0.3
One hour access (shock baseline)0.10.10.7-0.0-0.30.10.10.10.8-0.10.1-0.5
Number of responses in last shaping day0.40.41.0-0.2-0.6-0.5-0.50.61.0-0.6-0.5-0.7
Context. condit. distance diff. score2.43.04.0-1.31.72.02.0-2.0-1.12.02.01.2
Locomotion velocity, session 14.14.56.31.5-2.1-2.5-2.32.31.4-2.3-2.3-1.9
Locomotion distance, session 11.62.12.80.9-1.4-1.7-1.61.61.0-1.6-1.6-1.5
Locomotion velocity, session 20.40.41.7-0.80.80.10.1-0.1-1.30.10.11.0
Locomotion distance, session 20.50.71.00.8-0.8-1.0-0.91.0-0.2-1.0-0.9-0.7
Locomotion velocity, session 30.20.20.30.2-0.2-0.6-0.50.6-0.2-0.6-0.50.3
Locomotion distance, session 30.20.20.80.9-0.5-0.2-0.30.30.2-0.3-0.3-0.3
Stereotopy head waving bouts, day 32.83.35.4-2.32.01.81.8-1.8-0.71.81.81.9
Stereotopy head waving duration, day 33.44.16.9-2.62.41.81.7-1.7-1.51.71.72.5
Locomotion velocity, session 70.20.20.4-0.40.30.60.6-0.60.20.60.6-0.2
Locomotion distance, session 70.10.10.30.3-0.20.30.3-0.30.30.30.3-0.5
Stereotopy head waving bouts, day 70.10.10.2-0.30.20.30.4-0.30.40.30.40.2
Stereotopy head waving duration, day 70.10.10.5-0.0-0.2-0.0-0.00.10.7-0.1-0.00.0
Locomotion velocity, session 81.72.13.0-1.71.71.31.4-1.3-1.31.31.41.4
Locomotion distance, session 80.60.91.2-0.70.91.01.1-1.1-0.91.01.10.4
Degree of sensitization distance0.10.10.5-0.1-0.20.10.2-0.20.70.20.2-0.5
Degree of sensitization stereotypy0.30.31.10.6-0.7-0.2-0.20.31.1-0.3-0.2-0.7
Condit. Reinf. active minus inactive responses0.60.74.00.3-0.8-0.10.1-0.12.00.10.1-1.3
Condit. Reinf. active-inactive response ratio0.50.60.9-0.60.40.80.9-0.90.70.90.9-0.0
Condit. Reinf. active responses1.41.78.10.8-1.5-0.5-0.30.32.8-0.3-0.3-1.9
Condit. Reinf. inactive responses1.51.84.91.3-1.7-0.9-0.80.82.2-0.8-0.8-1.8
Incentive salience index mean1.41.76.30.7-1.5-0.8-0.60.62.5-0.6-0.6-1.9
Condit. Reinf. lever presses1.01.44.60.5-1.4-0.9-0.70.72.1-0.7-0.7-1.6
Time in familiar zone, hab. session 12.01.92.81.6-1.2-1.4-1.51.7-0.1-1.7-1.5-0.8
Time in novel zone, hab. session 13.13.04.4-1.81.51.92.0-2.10.32.12.01.0
Total zone transitions, hab. session 10.50.71.30.5-0.6-1.1-1.01.1-0.2-1.1-1.0-0.3
Total locomotion distance, hab. session 10.40.60.90.2-0.5-1.0-0.91.0-0.0-1.0-0.9-0.5
Locomotion velocity, hab. session 10.70.91.50.3-0.7-1.2-1.21.20.3-1.2-1.2-0.7
Time in familiar zone, hab. session 20.00.00.20.5-0.0-0.2-0.10.2-0.1-0.2-0.10.3
Time in novel zone, hab. session 20.70.71.4-1.20.71.00.8-1.0-0.11.00.80.3
Total zone transitions, hab. session 20.40.50.90.4-0.3-0.8-0.80.8-1.0-0.9-0.8-0.1
Total locomotion distance, hab. session 20.00.00.2-0.30.1-0.0-0.00.1-0.4-0.1-0.0-0.1
Locomotion velocity, hab. session 20.00.10.1-0.1-0.1-0.3-0.30.3-0.3-0.3-0.3-0.2
Novel to familiar place preference ratio2.12.23.1-1.71.41.71.6-1.7-0.11.81.60.9
Novelty place preference2.02.12.9-1.71.41.71.6-1.7-0.11.71.60.8
Time in novel zone, NPP test1.92.02.8-1.61.31.71.6-1.7-0.11.71.60.7
Total zone transitions, NPP test1.41.92.91.3-1.0-1.6-1.61.7-0.8-1.7-1.6-0.7
Total locomotion distance, NPP test0.30.40.80.1-0.2-0.7-0.80.8-0.9-0.8-0.8-0.3
Locomotion velocity, NPP test0.40.60.90.2-0.3-0.9-0.91.0-0.9-1.0-0.9-0.3
Pavlov. Cond. lever latency0.20.20.50.20.40.60.4-0.5-0.50.50.40.7
Pavlov. Cond. magazine entry latency1.01.32.3-1.50.51.11.2-1.21.41.21.2-0.6
Pavlov. Cond. change in total contacts0.20.20.4-0.40.10.40.5-0.50.00.50.5-0.6
Pavlov. Cond. index score0.20.31.1-0.4-0.4-0.3-0.10.11.1-0.1-0.1-1.0
Pavlov. Cond. latency score0.20.20.8-0.6-0.2-0.2-0.10.10.9-0.1-0.1-0.7
Pavlov. Cond. lever contacts0.30.30.6-0.1-0.5-0.7-0.50.50.6-0.5-0.5-0.7
Pavlov. Cond. magazine entry number0.70.81.51.2-0.4-0.8-0.90.9-1.1-0.9-0.90.7
Pavlov. Cond. intertrial magazine entries0.40.42.21.5-0.6-0.4-0.50.5-0.2-0.5-0.50.5
Pavlov. Cond. lever-magazine prob. diff.0.30.31.1-0.2-0.5-0.4-0.30.30.9-0.3-0.3-1.1
Pavlov. Cond. response bias0.30.31.5-0.2-0.4-0.00.1-0.11.10.10.1-1.2
Bone: apparent density0.91.52.7-0.91.31.01.0-1.0-1.71.01.01.6
Bone surface0.91.72.3-0.71.31.31.3-1.3-1.41.31.31.5
Bone volume1.01.72.4-0.81.31.41.3-1.3-1.31.31.31.6
Bone: connectivity density0.50.71.1-0.90.90.80.8-0.8-0.70.80.81.0
Bone: cortical apparent density0.81.12.51.6-1.3-0.8-0.70.71.2-0.7-0.8-1.2
Bone: cortical area1.92.93.3-1.61.81.81.8-1.8-1.21.81.81.7
Bone: cortical porosity1.21.32.00.7-0.6-1.4-1.41.4-0.7-1.4-1.4-0.5
Bone: cortical porosity0.20.20.5-0.20.1-0.5-0.50.5-0.7-0.5-0.50.2
Bone: cortical thickness1.22.02.5-1.51.61.41.4-1.4-1.21.41.41.5
Bone: cortical thickness0.30.41.80.90.1-0.3-0.30.3-1.3-0.3-0.30.8
Bone: cortical tissue density0.81.12.51.6-1.3-0.8-0.80.81.1-0.8-0.8-1.1
Bone: elastic displacement0.10.10.4-0.1-0.2-0.3-0.30.30.6-0.3-0.3-0.3
Bone: elastic work0.60.71.1-1.00.70.91.0-1.00.31.00.90.6
Bone: endosteal estimation0.00.10.40.30.20.30.3-0.3-0.60.30.30.4
Bone: endosteal perimeter0.00.00.00.2-0.00.00.0-0.0-0.10.00.1-0.1
Bone: final force1.11.82.8-1.01.11.71.7-1.7-0.01.71.60.7
Bone: final moment0.81.42.1-0.80.91.51.5-1.50.11.51.50.6
Bone: marrow area0.10.10.40.10.30.40.3-0.3-0.60.30.30.4
Bone: maximum diameter1.01.82.2-1.11.41.51.5-1.5-0.91.51.51.4
Bone: maximum force2.13.74.7-1.91.92.22.2-2.2-0.72.22.11.5
Bone: maximum moment1.62.83.5-1.71.61.91.9-1.9-0.61.91.91.3
Bone: minimum diameter0.91.73.1-1.71.71.01.0-1.0-1.41.01.01.8
Bone: periosteal estimation0.71.51.7-0.91.31.31.3-1.3-1.01.31.31.3
Bone: periosteal perimeter0.60.91.3-1.11.21.00.9-0.9-0.80.91.01.0
Bone: post-yield work0.10.10.50.1-0.0-0.3-0.30.3-0.7-0.3-0.3-0.1
Bone: stiffness1.62.53.0-1.51.51.71.7-1.7-0.91.71.71.3
Bone: tissue strength0.30.20.7-0.80.50.50.5-0.5-0.30.50.40.3
Bone: trabecular number1.82.94.5-1.11.81.71.6-1.6-2.11.61.61.9
Bone: trabecular spacing1.01.35.50.2-1.1-0.8-0.80.82.4-0.8-0.8-1.3
Bone: trabecular thickness0.40.41.51.2-0.5-0.6-0.60.6-0.5-0.6-0.6-0.2
Bone: trabecular tissue density2.83.97.12.7-1.9-2.0-2.12.1-0.7-2.1-2.1-1.6
Breakpoint value in progressive ratio session0.10.10.60.60.10.00.0-0.0-0.80.10.00.1
Distance traveled before self-admin0.20.20.4-0.50.40.50.4-0.5-0.50.50.50.6
Distance traveled after self-admin0.10.10.30.40.20.20.2-0.3-0.60.30.30.1
Delta time in closed arm before/after self-admin0.20.20.6-0.1-0.30.30.3-0.30.70.30.3-0.8
Delta time in open arm before/after self-admin2.01.94.4-0.31.31.41.3-1.4-2.11.41.31.5
Diff in mean of infusions in LGA sessions0.10.10.3-0.1-0.20.30.3-0.40.60.40.2-0.5
Extinction: sum of active levers before priming1.11.11.40.9-1.0-1.1-1.21.20.6-1.2-1.2-0.9
Active lever presses in extinction session 60.10.10.2-0.20.1-0.3-0.30.3-0.5-0.3-0.3-0.1
Delta distance traveled before/after self-admin0.20.20.50.7-0.4-0.5-0.30.30.3-0.3-0.3-0.6
Delta ambulatory time before/after self-admin0.30.30.90.4-0.5-0.4-0.30.20.9-0.2-0.3-1.0
Time in closed arm before self-admin2.12.42.81.4-1.6-1.6-1.71.71.3-1.7-1.6-1.2
Time in closed arm after self-admin1.51.55.00.8-1.4-0.9-0.80.82.2-0.8-0.8-1.6
Time in open arm before self-admin0.40.40.6-0.70.80.50.8-0.7-0.10.70.60.7
Time in open arm after self-admin3.33.76.1-0.92.11.91.9-1.9-2.51.91.82.1
Sum of active levers in priming session hrs 5-60.20.10.50.7-0.2-0.3-0.40.3-0.5-0.3-0.4-0.3
Time to tail flick, vehicle, before self-admin0.40.41.0-0.70.90.40.3-0.4-1.00.40.30.7
Time to tail flick, vehicle, after self-admin0.30.41.2-0.00.50.50.4-0.4-1.00.40.41.1
Time to tail flick, test, before self-admin0.60.61.0-1.00.90.80.9-0.90.10.90.80.6
Time to tail flick, test, after self-admin0.70.71.1-0.61.00.70.9-0.9-0.90.90.81.1
Delta time to tail flick, vehicle, before/after SA0.80.81.1-0.20.71.01.1-0.9-0.90.91.00.9
Delta time to tail flick, test, before/after SA0.10.10.4-0.10.20.30.1-0.2-0.50.20.20.6
Ambulatory time before self-admin0.20.20.5-0.70.40.50.3-0.5-0.20.50.30.6
Ambulatory time after self-admin0.30.30.80.8-0.6-0.4-0.40.30.4-0.3-0.3-0.9
Total heroin consumption0.10.20.30.1-0.1-0.3-0.60.5-0.6-0.4-0.5-0.1
Area under the delay curve0.80.81.9-1.31.20.50.5-0.5-1.40.50.51.1
Delay disc. indifference point, 0s delay0.20.20.9-0.6-0.3-0.3-0.30.31.0-0.3-0.3-0.2
Delay disc. indifference point, 16s delay0.20.20.3-0.10.1-0.5-0.50.5-0.5-0.5-0.50.3
Delay disc. indifference point, 2s delay0.60.71.0-0.90.71.01.0-1.0-0.31.01.00.2
Delay disc. indifference point, 24s delay1.41.42.00.7-1.0-1.4-1.31.30.7-1.3-1.4-1.2
Delay disc. indifference point, 4s delay0.30.31.0-1.00.70.30.2-0.3-0.90.30.30.7
Delay disc. indifference point, 8s delay2.32.43.9-1.91.91.21.1-1.2-1.91.21.12.0
Delay discount exponential model param0.50.51.71.0-0.9-0.3-0.30.31.3-0.3-0.3-0.8
Delay discount hyperbolic model param0.70.71.51.2-1.1-0.6-0.50.51.2-0.5-0.6-0.9
Fecal boli incidents, locomotor time 11.21.32.11.0-1.1-1.3-1.31.40.3-1.4-1.4-0.5
Change in fecal boli incidents, locomotor task4.03.84.9-1.82.02.22.0-2.1-1.52.12.01.7
Time >=10cm from walls, locomotor time 10.00.00.30.5-0.1-0.10.00.10.0-0.10.00.0
Bouts of movement, locomotor time 14.04.55.82.1-2.2-2.4-2.42.41.0-2.4-2.2-1.6
Total resting periods, locomotor time 13.94.35.12.0-2.2-2.3-2.22.31.3-2.3-2.2-1.7
Rest time, locomotor task time 10.00.00.1-0.0-0.10.20.1-0.20.00.20.10.2
Distance moved, locomotor task time 10.30.31.20.3-0.5-0.3-0.30.21.1-0.2-0.4-0.7
Vertical activity count, locomotor time 10.10.10.1-0.10.40.30.4-0.4-0.10.40.40.1
Time >=10cm from walls, locomotor time 212.112.814.9-3.73.93.83.7-3.7-2.43.73.73.3
Bouts of movement, locomotor time 20.10.10.60.30.30.10.2-0.2-0.40.10.20.8
Total resting periods, locomotor time 20.10.10.40.50.2-0.00.1-0.1-0.20.00.10.6
Rest time, locomotor task time 24.85.66.72.5-2.6-2.4-2.42.31.9-2.3-2.4-2.5
Distance moved, locomotor task time 22.42.84.2-2.01.71.81.8-1.8-0.71.81.71.2
Vertical activity count, locomotor time 25.25.77.2-2.22.52.62.7-2.5-1.42.52.62.1
Weight adjusted by age1.01.12.3-1.51.01.11.1-1.10.11.11.10.4
Seeking ratio, delayed vs. immediate footshock0.80.91.6-0.40.71.21.1-1.2-0.61.31.10.2
Locomotion in novel chamber0.81.01.5-1.21.01.01.0-1.0-0.21.01.10.8
Locomotion in novel chamber post-restriction1.61.94.7-0.71.51.21.2-1.3-2.21.31.31.4
Progressive ratio0.30.30.60.7-0.3-0.7-0.40.6-0.4-0.7-0.80.0
Food seeking constrained by brief footshock0.00.00.1-0.30.1-0.00.20.00.2-0.0-0.1-0.1
Seeking ratio, punishment vs. effort0.10.21.0-0.4-0.20.20.1-0.11.00.20.1-0.5
Run reversals in cocaine runway, females0.20.21.50.30.20.10.1-0.0-1.20.00.00.1
Run reversals in cocaine runway, males1.71.62.11.3-1.2-1.4-1.21.41.0-1.4-1.4-1.1
Latency to leave start box in cocaine runway0.00.00.20.2-0.10.10.2-0.10.50.10.1-0.0
Latency to leave start box in cocaine runway, F0.10.20.30.1-0.4-0.5-0.40.50.2-0.5-0.6-0.1
Latency to leave start box in cocaine runway, M0.60.61.00.00.30.91.0-1.00.60.91.0-0.1
Cd content in liver0.20.20.5-0.30.60.40.4-0.3-0.70.30.40.7
Co content in liver0.30.30.50.3-0.3-0.6-0.70.7-0.5-0.7-0.7-0.1
Cu content in liver0.50.71.81.3-0.6-0.8-0.80.9-0.5-0.9-0.7-0.3
Fe content in liver1.51.86.11.4-1.6-0.7-0.60.72.5-0.7-0.6-1.8
K content in liver0.40.42.1-0.10.60.10.1-0.2-1.40.20.20.8
Mg content in liver1.11.24.7-0.01.00.70.7-0.7-2.20.70.71.4
Mn content in liver0.70.81.3-1.21.10.80.8-0.9-0.80.90.80.8
Na content in liver1.51.62.31.5-1.4-1.3-1.31.20.6-1.2-1.3-1.2
Rb content in liver4.55.78.6-1.82.72.22.2-2.2-2.92.22.32.7
Se content in liver0.20.20.3-0.20.40.50.5-0.5-0.40.50.50.3
Sr content in liver0.40.30.70.1-0.2-0.8-0.70.80.0-0.8-0.7-0.1
Zn content in liver0.50.51.01.0-0.6-0.8-0.80.8-0.4-0.8-0.8-0.5