# | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | alternative polyA | ENSRNOT00000094178 | 0.0503 | 0.04000 | 1.5e-05 | 0.032 | 0.031 | 0.031 | 0.030 | 1.5e-04 | 2.2e-04 | 2.1e-04 | 2.3e-04 |
2 | Adipose | alternative polyA | ENSRNOT00000095175 | 0.0509 | 0.04020 | 1.2e-05 | 0.033 | 0.031 | 0.031 | 0.030 | 1.3e-04 | 2.0e-04 | 2.0e-04 | 2.3e-04 |
3 | Adipose | gene expression | ENSRNOG00000007551 | 0.2000 | 0.11000 | 0.0e+00 | 0.128 | 0.123 | 0.128 | 0.130 | 4.6e-14 | 1.4e-13 | 4.4e-14 | 3.3e-14 |
4 | Adipose | isoform ratio | ENSRNOT00000094178 | 0.0340 | 0.03200 | 1.1e-03 | 0.014 | 0.009 | 0.015 | 0.010 | 9.4e-03 | 2.8e-02 | 8.1e-03 | 2.6e-02 |
5 | BLA | gene expression | ENSRNOG00000007551 | 0.0439 | 0.04344 | 9.2e-03 | 0.024 | 0.013 | 0.005 | 0.020 | 1.8e-02 | 6.2e-02 | 1.6e-01 | 2.7e-02 |
6 | BLA | intron excision ratio | chr5:113131176:113135005 | 0.0530 | 0.05600 | 7.9e-03 | 0.031 | 0.029 | 0.029 | 0.027 | 8.3e-03 | 1.1e-02 | 1.1e-02 | 1.3e-02 |
7 | Brain | gene expression | ENSRNOG00000007551 | 0.2800 | 0.14000 | 0.0e+00 | 0.304 | 0.304 | 0.300 | 0.300 | 1.5e-28 | 1.5e-28 | 3.5e-28 | 3.7e-28 |
8 | Brain | isoform ratio | ENSRNOT00000010211 | 0.3099 | 0.14424 | 0.0e+00 | 0.355 | 0.368 | 0.359 | 0.366 | 3.2e-34 | 1.0e-35 | 1.3e-34 | 2.0e-35 |
9 | Brain | intron excision ratio | chr5:113208549:113235070 | 0.0546 | 0.04929 | 1.0e-04 | 0.025 | 0.038 | 0.035 | 0.036 | 1.9e-03 | 1.9e-04 | 3.2e-04 | 2.7e-04 |
10 | Brain | intron excision ratio | chr5:113282422:113299279 | 0.2253 | 0.17201 | 7.2e-09 | 0.099 | 0.093 | 0.099 | 0.099 | 1.9e-09 | 6.1e-09 | 1.9e-09 | 2.1e-09 |
11 | Brain | mRNA stability | ENSRNOG00000007551 | 0.0993 | 0.07446 | 7.2e-09 | 0.097 | 0.094 | 0.093 | 0.094 | 2.7e-09 | 4.6e-09 | 5.7e-09 | 5.4e-09 |
12 | LHb | isoform ratio | ENSRNOT00000010211 | 0.8816 | 0.12741 | 2.0e-03 | 0.081 | 0.066 | 0.018 | 0.066 | 5.7e-03 | 1.2e-02 | 1.2e-01 | 1.2e-02 |
13 | LHb | isoform ratio | ENSRNOT00000101438 | 0.9967 | 0.00053 | 3.5e-05 | 0.058 | 0.083 | 0.017 | 0.104 | 1.7e-02 | 5.3e-03 | 1.3e-01 | 1.9e-03 |
14 | Liver | gene expression | ENSRNOG00000007551 | 0.2500 | 0.16000 | 3.5e-13 | 0.085 | 0.080 | 0.077 | 0.081 | 1.1e-09 | 3.6e-09 | 7.0e-09 | 2.7e-09 |
15 | Liver | isoform ratio | ENSRNOT00000010211 | 0.0390 | 0.03340 | 2.8e-04 | 0.016 | 0.019 | 0.012 | 0.015 | 6.4e-03 | 3.2e-03 | 1.5e-02 | 8.1e-03 |
16 | Liver | isoform ratio | ENSRNOT00000101438 | 0.1654 | 0.14070 | 8.3e-09 | 0.051 | 0.047 | 0.045 | 0.044 | 2.6e-06 | 5.3e-06 | 8.0e-06 | 1.0e-05 |
17 | NAcc | alternative TSS | ENSRNOT00000095175 | 0.0510 | 0.04900 | 4.4e-04 | 0.043 | 0.043 | 0.043 | 0.042 | 3.5e-04 | 3.8e-04 | 3.7e-04 | 3.9e-04 |
18 | NAcc | alternative TSS | ENSRNOT00000103328 | 0.0430 | 0.04200 | 1.1e-03 | 0.043 | 0.036 | 0.038 | 0.037 | 3.7e-04 | 1.0e-03 | 7.7e-04 | 8.5e-04 |
19 | NAcc | gene expression | ENSRNOG00000007551 | 0.1700 | 0.11000 | 3.9e-13 | 0.177 | 0.181 | 0.181 | 0.179 | 3.3e-13 | 1.8e-13 | 1.9e-13 | 2.5e-13 |
20 | NAcc | isoform ratio | ENSRNOT00000010211 | 0.1336 | 0.16237 | 9.1e-07 | 0.080 | 0.086 | 0.081 | 0.079 | 1.5e-06 | 5.5e-07 | 1.2e-06 | 1.7e-06 |
21 | NAcc | isoform ratio | ENSRNOT00000103328 | 0.0421 | 0.04689 | 2.9e-03 | 0.026 | 0.016 | 0.022 | 0.022 | 4.5e-03 | 2.0e-02 | 8.5e-03 | 8.8e-03 |
22 | NAcc | intron excision ratio | chr5:113199348:113235070 | 0.0385 | 0.03850 | 2.5e-03 | 0.044 | 0.034 | 0.038 | 0.043 | 3.2e-04 | 1.3e-03 | 7.3e-04 | 3.9e-04 |
23 | NAcc | mRNA stability | ENSRNOG00000007551 | 0.0573 | 0.05083 | 1.3e-04 | 0.046 | 0.040 | 0.038 | 0.041 | 2.5e-04 | 5.5e-04 | 8.2e-04 | 4.9e-04 |
24 | OFC | alternative TSS | ENSRNOT00000095175 | 0.1240 | 0.12000 | 9.8e-03 | 0.048 | 0.071 | 0.051 | 0.042 | 2.7e-02 | 9.2e-03 | 2.4e-02 | 3.7e-02 |
25 | OFC | gene expression | ENSRNOG00000007551 | 0.1355 | 0.12690 | 8.4e-03 | 0.066 | 0.085 | 0.073 | 0.072 | 1.2e-02 | 4.7e-03 | 8.5e-03 | 8.8e-03 |
26 | PL | gene expression | ENSRNOG00000007551 | 0.0960 | 0.09960 | 1.1e-05 | 0.072 | 0.069 | 0.066 | 0.071 | 3.9e-06 | 5.7e-06 | 9.6e-06 | 4.1e-06 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 |
---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bone: trabecular tissue density | 15.5 | 21.7 | 23.1 | 4.7 | -4.7 | -4.6 | 4.7 | -4.6 | -4.7 | -4.8 | 4.8 | 4.8 | 4.6 | 4.7 | 4.8 | -2.7 | -4.8 | 4.8 | -4.7 | -4.7 | 4.7 | 4.8 | 4.8 | 4.7 | -4.7 | 4.7 | 4.8 | -4.8 | -4.6 |
Tibialis anterior weight | 7.5 | 26.0 | 27.5 | -5.1 | 5.1 | 5.1 | -5.1 | 5.1 | 5.2 | 5.2 | -5.2 | -5.2 | -5.1 | -5.2 | -5.2 | 3.0 | 5.2 | -5.2 | 5.1 | 5.2 | -5.2 | -5.2 | -5.2 | -5.2 | 5.1 | -5.1 | -5.2 | 5.2 | 5.1 |
Bone: cortical apparent density | 7.5 | 9.8 | 10.4 | 3.1 | -3.1 | -3.1 | 3.1 | -3.2 | -3.2 | -3.2 | 3.2 | 3.2 | 3.1 | 3.2 | 3.2 | -1.8 | -3.2 | 3.2 | -3.2 | -3.1 | 3.1 | 3.2 | 3.2 | 3.1 | -3.2 | 3.2 | 3.2 | -3.2 | -3.0 |
Bone: cortical tissue density | 7.3 | 9.5 | 10.1 | 3.1 | -3.1 | -3.0 | 3.1 | -3.2 | -3.2 | -3.2 | 3.2 | 3.2 | 3.0 | 3.1 | 3.2 | -1.7 | -3.2 | 3.2 | -3.2 | -3.1 | 3.1 | 3.2 | 3.2 | 3.0 | -3.1 | 3.1 | 3.2 | -3.2 | -3.0 |
Time in novel zone, hab. session 1 | 7.2 | 7.0 | 7.7 | -2.7 | 2.7 | 2.6 | -2.7 | 2.8 | 2.7 | 2.7 | -2.7 | -2.7 | -2.6 | -2.8 | -2.7 | 1.3 | 2.7 | -2.7 | 2.7 | 2.6 | -2.6 | -2.7 | -2.7 | -2.6 | 2.7 | -2.7 | -2.7 | 2.7 | 2.6 |
Mean time between licks in bursts | 6.5 | 9.1 | 9.7 | 3.0 | -3.0 | -3.0 | 3.0 | -3.1 | -3.1 | -3.0 | 3.1 | 3.1 | 3.0 | 3.0 | 3.1 | -2.2 | -3.0 | 3.1 | -3.0 | -3.0 | 3.0 | 3.1 | 3.1 | 3.0 | -3.0 | 3.0 | 3.1 | -3.1 | -3.0 |
Liver weight, right | 6.3 | 10.5 | 11.2 | 3.3 | -3.3 | -3.2 | 3.3 | -3.2 | -3.3 | -3.3 | 3.3 | 3.3 | 3.3 | 3.3 | 3.2 | -1.9 | -3.2 | 3.3 | -3.2 | -3.1 | 3.1 | 3.3 | 3.4 | 3.2 | -3.3 | 3.3 | 3.3 | -3.3 | -3.3 |
Compulsive drug intake | 6.3 | 6.3 | 8.2 | -2.5 | 2.5 | 2.8 | -2.6 | 2.6 | 2.2 | 2.3 | -2.4 | -2.5 | -2.9 | -2.4 | -2.2 | 1.7 | 2.5 | -2.4 | 2.5 | 2.6 | -2.6 | -2.4 | -2.6 | -2.8 | 2.6 | -2.6 | -2.5 | 2.4 | 2.9 |
Progressive ratio test 1 breakpoint | 5.8 | 6.0 | 8.2 | 2.5 | -2.5 | -2.1 | 2.6 | -2.5 | -2.5 | -2.6 | 2.5 | 2.5 | 2.1 | 2.8 | 2.2 | 0.8 | -2.9 | 2.5 | -2.9 | -2.2 | 2.2 | 2.5 | 2.5 | 2.2 | -2.7 | 2.7 | 2.5 | -2.5 | -2.1 |
Indifference point 0 sec | 5.7 | 9.2 | 11.1 | -2.9 | 2.9 | 3.2 | -2.9 | 2.7 | 2.9 | 3.0 | -3.1 | -3.1 | -3.2 | -2.9 | -3.3 | 3.0 | 3.1 | -3.1 | 3.0 | 3.1 | -3.1 | -3.1 | -3.0 | -3.1 | 3.0 | -3.0 | -3.1 | 3.1 | 3.2 |
Parametrial fat weight | 5.1 | 10.0 | 10.7 | -3.2 | 3.2 | 3.2 | -3.1 | 3.3 | 3.1 | 3.2 | -3.2 | -3.2 | -3.2 | -3.2 | -3.2 | 1.9 | 3.2 | -3.2 | 3.1 | 3.3 | -3.3 | -3.2 | -3.3 | -3.3 | 3.2 | -3.2 | -3.2 | 3.2 | 3.2 |
Delay discounting total patch changes 0 sec | 5.1 | 8.2 | 10.3 | -2.7 | 2.7 | 3.0 | -2.7 | 2.5 | 2.8 | 2.9 | -2.9 | -2.9 | -3.0 | -2.8 | -3.2 | 3.0 | 2.9 | -2.9 | 2.8 | 2.9 | -2.9 | -2.9 | -2.9 | -2.9 | 2.7 | -2.7 | -2.9 | 2.9 | 3.0 |
Total zone transitions, hab. session 2 | 4.9 | 6.3 | 8.0 | 2.4 | -2.4 | -2.8 | 2.4 | -2.4 | -2.4 | -2.4 | 2.5 | 2.5 | 2.8 | 2.4 | 2.4 | -2.5 | -2.4 | 2.5 | -2.4 | -2.7 | 2.7 | 2.5 | 2.6 | 2.7 | -2.4 | 2.4 | 2.5 | -2.5 | -2.8 |
Progressive ratio test 1 active lever presses | 4.5 | 4.6 | 6.8 | 2.2 | -2.2 | -1.8 | 2.3 | -2.2 | -2.3 | -2.3 | 2.2 | 2.2 | 1.8 | 2.5 | 2.1 | 0.6 | -2.6 | 2.2 | -2.5 | -1.8 | 1.8 | 2.2 | 2.2 | 1.8 | -2.4 | 2.4 | 2.2 | -2.2 | -1.8 |
Food seeking constrained by brief footshock | 3.9 | 4.7 | 5.8 | 2.1 | -2.1 | -2.2 | 2.1 | -2.1 | -2.3 | -2.2 | 2.2 | 2.2 | 2.2 | 2.1 | 2.4 | -2.2 | -2.1 | 2.2 | -2.1 | -2.0 | 2.0 | 2.2 | 2.2 | 2.1 | -2.1 | 2.1 | 2.2 | -2.2 | -2.2 |
Delay disc. indifference point, 4s delay | 3.8 | 4.0 | 5.2 | 2.0 | -2.0 | -2.1 | 2.0 | -2.3 | -1.9 | -2.0 | 2.1 | 2.1 | 2.1 | 2.0 | 1.8 | -1.3 | -2.0 | 2.0 | -1.9 | -2.1 | 2.1 | 2.0 | 2.1 | 2.1 | -2.0 | 2.0 | 2.1 | -2.0 | -2.1 |
Delay discounting water rate 12 sec | 3.3 | 4.9 | 6.3 | -2.1 | 2.1 | 2.3 | -2.1 | 2.2 | 2.3 | 2.2 | -2.3 | -2.3 | -2.3 | -2.3 | -2.5 | 2.0 | 2.1 | -2.3 | 2.1 | 2.3 | -2.3 | -2.3 | -2.2 | -2.3 | 2.2 | -2.2 | -2.3 | 2.3 | 2.3 |
Na content in liver | 3.2 | 3.4 | 3.9 | 1.8 | -1.8 | -2.0 | 1.8 | -1.8 | -1.8 | -1.8 | 1.9 | 1.9 | 2.0 | 1.9 | 1.9 | -1.4 | -1.9 | 1.9 | -1.8 | -1.9 | 1.9 | 1.9 | 1.9 | 1.9 | -1.8 | 1.8 | 1.9 | -1.9 | -2.0 |
One hour access (shock baseline) | 3.0 | 3.4 | 4.2 | 1.8 | -1.8 | -2.0 | 1.9 | -1.9 | -1.8 | -1.8 | 1.9 | 1.9 | 2.0 | 1.9 | 1.5 | -1.1 | -1.9 | 1.9 | -1.8 | -1.9 | 1.9 | 1.8 | 2.0 | 2.1 | -1.9 | 1.9 | 1.9 | -1.8 | -2.0 |
Time in familiar zone, hab. session 1 | 2.8 | 2.6 | 2.9 | 1.6 | -1.6 | -1.6 | 1.6 | -1.7 | -1.6 | -1.6 | 1.7 | 1.7 | 1.7 | 1.7 | 1.6 | -1.1 | -1.6 | 1.7 | -1.6 | -1.6 | 1.6 | 1.7 | 1.7 | 1.6 | -1.6 | 1.6 | 1.7 | -1.7 | -1.7 |
Sum of active levers in priming session hrs 5-6 | 2.8 | 2.7 | 4.3 | 1.7 | -1.7 | -1.9 | 1.7 | -1.8 | -1.4 | -1.3 | 1.5 | 1.6 | 1.9 | 1.6 | 1.2 | -0.8 | -1.5 | 1.5 | -1.6 | -2.1 | 2.1 | 1.4 | 1.7 | 2.0 | -1.7 | 1.7 | 1.5 | -1.5 | -1.9 |
Condit. Reinf. lever presses | 2.6 | 3.7 | 4.3 | -2.0 | 2.0 | 1.8 | -2.0 | 2.1 | 1.9 | 1.9 | -1.9 | -2.0 | -1.8 | -1.9 | -2.0 | 0.9 | 1.9 | -1.9 | 2.0 | 1.9 | -1.9 | -1.9 | -1.9 | -2.0 | 2.0 | -2.0 | -1.9 | 1.9 | 1.8 |
Context. condit. distance diff. score | 2.6 | 3.1 | 3.6 | 1.8 | -1.8 | -1.7 | 1.8 | -1.8 | -1.9 | -1.8 | 1.8 | 1.8 | 1.6 | 1.9 | 1.9 | -0.7 | -1.9 | 1.8 | -1.9 | -1.7 | 1.7 | 1.8 | 1.8 | 1.7 | -1.8 | 1.8 | 1.8 | -1.8 | -1.6 |
Heart weight | 2.5 | 3.5 | 4.7 | 1.9 | -1.9 | -1.7 | 1.9 | -1.9 | -2.1 | -2.0 | 1.9 | 1.9 | 1.6 | 2.1 | 2.2 | -0.9 | -2.1 | 1.9 | -2.0 | -1.7 | 1.7 | 2.0 | 1.9 | 1.7 | -1.9 | 1.9 | 1.9 | -1.9 | -1.6 |
Tibia length | 2.5 | 7.0 | 7.8 | 2.6 | -2.6 | -2.8 | 2.6 | -2.7 | -2.5 | -2.6 | 2.7 | 2.7 | 2.8 | 2.7 | 2.5 | -1.6 | -2.7 | 2.7 | -2.6 | -2.8 | 2.8 | 2.6 | 2.7 | 2.7 | -2.6 | 2.6 | 2.7 | -2.6 | -2.8 |
Epididymis fat weight | 2.4 | 5.5 | 6.4 | 2.4 | -2.4 | -2.5 | 2.4 | -2.2 | -2.2 | -2.2 | 2.3 | 2.4 | 2.5 | 2.3 | 2.3 | -2.1 | -2.4 | 2.3 | -2.4 | -2.3 | 2.3 | 2.3 | 2.4 | 2.4 | -2.4 | 2.4 | 2.4 | -2.3 | -2.5 |
Progressive ratio test 1 inactive lever presses | 2.3 | 2.5 | 4.2 | 1.7 | -1.7 | -1.2 | 1.8 | -1.6 | -2.0 | -1.7 | 1.6 | 1.5 | 1.2 | 2.0 | 1.3 | 0.9 | -1.9 | 1.6 | -1.9 | -1.2 | 1.2 | 1.6 | 1.6 | 1.1 | -1.7 | 1.7 | 1.6 | -1.6 | -1.2 |
Delay disc. indifference point, 0s delay | 2.3 | 2.5 | 3.1 | 1.6 | -1.6 | -1.5 | 1.6 | -1.6 | -1.8 | -1.7 | 1.6 | 1.6 | 1.5 | 1.6 | 1.7 | -1.1 | -1.6 | 1.6 | -1.6 | -1.5 | 1.5 | 1.7 | 1.6 | 1.6 | -1.6 | 1.6 | 1.6 | -1.6 | -1.5 |
Delay disc. indifference point, 8s delay | 2.3 | 2.4 | 3.0 | 1.6 | -1.6 | -1.7 | 1.5 | -1.6 | -1.5 | -1.5 | 1.6 | 1.6 | 1.7 | 1.6 | 1.4 | -0.8 | -1.5 | 1.6 | -1.5 | -1.7 | 1.7 | 1.5 | 1.6 | 1.7 | -1.5 | 1.5 | 1.6 | -1.6 | -1.7 |
Weight adjusted by age | 2.3 | 2.6 | 3.3 | -1.6 | 1.6 | 1.7 | -1.6 | 1.5 | 1.5 | 1.6 | -1.7 | -1.7 | -1.6 | -1.8 | -1.5 | 0.2 | 1.7 | -1.7 | 1.7 | 1.7 | -1.7 | -1.6 | -1.7 | -1.7 | 1.6 | -1.6 | -1.7 | 1.7 | 1.6 |
Total locomotion distance, hab. session 2 | 2.1 | 2.7 | 4.3 | 1.5 | -1.5 | -1.9 | 1.5 | -1.5 | -1.5 | -1.4 | 1.6 | 1.6 | 2.0 | 1.5 | 1.5 | -2.1 | -1.5 | 1.6 | -1.5 | -1.9 | 1.9 | 1.6 | 1.7 | 1.9 | -1.5 | 1.5 | 1.6 | -1.6 | -2.0 |
Time >=10cm from walls, locomotor time 2 | 2.1 | 2.3 | 3.3 | 1.4 | -1.4 | -1.5 | 1.4 | -1.4 | -1.8 | -1.6 | 1.6 | 1.6 | 1.5 | 1.5 | 1.6 | -1.4 | -1.4 | 1.6 | -1.4 | -1.4 | 1.4 | 1.6 | 1.5 | 1.4 | -1.5 | 1.5 | 1.6 | -1.6 | -1.5 |
Liver weight, left | 2.0 | 3.2 | 3.9 | 2.0 | -2.0 | -1.6 | 1.9 | -1.9 | -1.9 | -1.9 | 1.8 | 1.8 | 1.5 | 1.9 | 1.8 | -0.2 | -2.0 | 1.8 | -2.0 | -1.6 | 1.6 | 1.8 | 1.8 | 1.6 | -1.9 | 1.9 | 1.8 | -1.8 | -1.6 |
Pavlov. Cond. lever contacts | 2.0 | 2.8 | 3.3 | -1.7 | 1.7 | 1.7 | -1.7 | 1.8 | 1.5 | 1.6 | -1.7 | -1.7 | -1.7 | -1.6 | -1.7 | 1.2 | 1.7 | -1.7 | 1.8 | 1.7 | -1.7 | -1.6 | -1.7 | -1.7 | 1.7 | -1.7 | -1.7 | 1.7 | 1.7 |
Intermitt. access escalation Index | 2.0 | 1.8 | 2.5 | -1.5 | 1.5 | 1.4 | -1.5 | 1.6 | 1.2 | 1.1 | -1.2 | -1.2 | -1.4 | -1.4 | -0.9 | -0.2 | 1.5 | -1.2 | 1.5 | 1.4 | -1.4 | -1.1 | -1.4 | -1.2 | 1.5 | -1.5 | -1.2 | 1.2 | 1.4 |
Short access day 10 total inactive lever presses | 2.0 | 2.2 | 2.7 | -1.6 | 1.6 | 1.6 | -1.6 | 1.6 | 1.0 | 1.4 | -1.5 | -1.5 | -1.6 | -1.4 | -1.6 | 1.4 | 1.3 | -1.5 | 1.2 | 1.5 | -1.5 | -1.5 | -1.5 | -1.5 | 1.5 | -1.5 | -1.5 | 1.5 | 1.6 |
Bone surface | 2.0 | 3.5 | 3.9 | -1.9 | 1.9 | 1.8 | -1.9 | 1.9 | 1.9 | 1.9 | -1.9 | -1.9 | -1.8 | -1.9 | -2.0 | 1.1 | 1.9 | -1.9 | 1.9 | 1.7 | -1.7 | -1.9 | -1.9 | -1.7 | 1.9 | -1.9 | -1.9 | 1.9 | 1.8 |
Delay discounting time to switch 0 sec | 1.9 | 2.9 | 3.8 | 1.6 | -1.6 | -1.8 | 1.6 | -1.7 | -1.9 | -1.7 | 1.7 | 1.7 | 1.7 | 1.7 | 1.7 | -1.4 | -1.6 | 1.7 | -1.5 | -1.9 | 1.9 | 1.7 | 1.7 | 1.9 | -1.6 | 1.6 | 1.7 | -1.7 | -1.7 |
Condit. Reinf. inactive responses | 1.9 | 2.4 | 3.1 | 1.5 | -1.5 | -1.7 | 1.5 | -1.4 | -1.5 | -1.5 | 1.6 | 1.6 | 1.8 | 1.5 | 1.5 | -1.5 | -1.5 | 1.5 | -1.5 | -1.5 | 1.5 | 1.5 | 1.6 | 1.6 | -1.5 | 1.5 | 1.6 | -1.5 | -1.8 |
Pavlov. Cond. change in total contacts | 1.9 | 2.7 | 3.1 | -1.7 | 1.7 | 1.6 | -1.7 | 1.8 | 1.6 | 1.6 | -1.6 | -1.7 | -1.6 | -1.6 | -1.6 | 0.8 | 1.7 | -1.7 | 1.7 | 1.6 | -1.6 | -1.6 | -1.7 | -1.7 | 1.7 | -1.7 | -1.6 | 1.6 | 1.6 |
Total zone transitions, hab. session 1 | 1.9 | 2.6 | 3.5 | 1.6 | -1.6 | -1.8 | 1.6 | -1.6 | -1.5 | -1.5 | 1.6 | 1.7 | 1.7 | 1.6 | 1.5 | -1.3 | -1.6 | 1.6 | -1.6 | -1.9 | 1.9 | 1.6 | 1.7 | 1.9 | -1.6 | 1.6 | 1.6 | -1.6 | -1.7 |
Locomotion velocity, hab. session 2 | 1.8 | 2.4 | 4.0 | 1.4 | -1.4 | -1.8 | 1.4 | -1.4 | -1.3 | -1.3 | 1.5 | 1.5 | 1.9 | 1.3 | 1.3 | -2.0 | -1.4 | 1.5 | -1.4 | -1.8 | 1.8 | 1.4 | 1.6 | 1.8 | -1.4 | 1.4 | 1.5 | -1.5 | -1.9 |
Total zone transitions, NPP test | 1.8 | 2.6 | 3.1 | 1.6 | -1.6 | -1.7 | 1.6 | -1.7 | -1.5 | -1.5 | 1.6 | 1.6 | 1.7 | 1.6 | 1.5 | -1.0 | -1.7 | 1.6 | -1.7 | -1.8 | 1.8 | 1.6 | 1.7 | 1.8 | -1.6 | 1.6 | 1.6 | -1.6 | -1.7 |
Bone: connectivity density | 1.8 | 2.8 | 3.1 | -1.6 | 1.6 | 1.7 | -1.6 | 1.7 | 1.6 | 1.7 | -1.7 | -1.7 | -1.8 | -1.6 | -1.7 | 1.3 | 1.7 | -1.7 | 1.6 | 1.7 | -1.7 | -1.7 | -1.7 | -1.7 | 1.7 | -1.7 | -1.7 | 1.7 | 1.8 |
Delay discounting total patch changes 6 sec | 1.7 | 2.6 | 3.5 | -1.5 | 1.5 | 1.7 | -1.5 | 1.2 | 1.6 | 1.6 | -1.6 | -1.6 | -1.7 | -1.5 | -1.9 | 1.9 | 1.7 | -1.6 | 1.6 | 1.6 | -1.6 | -1.7 | -1.5 | -1.6 | 1.5 | -1.5 | -1.6 | 1.6 | 1.7 |
Total sessions with >9 infusions | 1.7 | 1.9 | 2.6 | 1.5 | -1.5 | -1.3 | 1.6 | -1.3 | -1.6 | -1.4 | 1.4 | 1.4 | 1.3 | 1.5 | 1.2 | 0.2 | -1.6 | 1.4 | -1.6 | -1.2 | 1.2 | 1.4 | 1.4 | 1.2 | -1.5 | 1.5 | 1.4 | -1.4 | -1.3 |
Time to tail flick, vehicle, after self-admin | 1.7 | 1.8 | 2.6 | -1.4 | 1.4 | 1.3 | -1.3 | 1.3 | 1.6 | 1.3 | -1.3 | -1.3 | -1.4 | -1.6 | -1.4 | 0.7 | 1.5 | -1.3 | 1.4 | 1.2 | -1.2 | -1.3 | -1.3 | -1.2 | 1.3 | -1.3 | -1.3 | 1.3 | 1.4 |
Delay discounting total patch changes 18 sec | 1.6 | 2.1 | 5.7 | -1.2 | 1.2 | 1.5 | -1.2 | 1.1 | 1.4 | 1.4 | -1.4 | -1.4 | -1.5 | -1.2 | -1.8 | 2.4 | 1.5 | -1.4 | 1.3 | 1.4 | -1.4 | -1.4 | -1.4 | -1.4 | 1.2 | -1.2 | -1.4 | 1.4 | 1.5 |
Pavlov. Cond. response bias | 1.6 | 2.2 | 2.5 | -1.5 | 1.5 | 1.6 | -1.5 | 1.6 | 1.3 | 1.4 | -1.4 | -1.5 | -1.6 | -1.4 | -1.4 | 1.3 | 1.5 | -1.4 | 1.5 | 1.5 | -1.5 | -1.4 | -1.5 | -1.6 | 1.5 | -1.5 | -1.5 | 1.4 | 1.6 |
Time in open arm after self-admin | 1.6 | 1.7 | 3.6 | -1.1 | 1.1 | 1.1 | -1.2 | 1.2 | 1.4 | 1.5 | -1.5 | -1.4 | -1.0 | -1.4 | -1.9 | 1.6 | 1.0 | -1.4 | 1.1 | 1.2 | -1.2 | -1.5 | -1.3 | -1.2 | 1.2 | -1.2 | -1.4 | 1.5 | 1.0 |
Delay discounting water rate 0 sec | 1.5 | 2.5 | 3.5 | -1.5 | 1.5 | 1.5 | -1.5 | 1.5 | 1.9 | 1.7 | -1.7 | -1.6 | -1.5 | -1.7 | -1.7 | 0.9 | 1.5 | -1.7 | 1.4 | 1.6 | -1.6 | -1.7 | -1.6 | -1.6 | 1.5 | -1.5 | -1.7 | 1.7 | 1.5 |
Std. dev. reaction times | 1.5 | 2.1 | 3.2 | -1.7 | 1.7 | 1.2 | -1.7 | 1.6 | 1.5 | 1.6 | -1.5 | -1.4 | -1.1 | -1.6 | -1.4 | -0.3 | 1.6 | -1.5 | 1.8 | 1.2 | -1.2 | -1.5 | -1.4 | -1.2 | 1.5 | -1.5 | -1.5 | 1.5 | 1.1 |
Pavlov. Cond. magazine entry latency | 1.5 | 1.7 | 2.2 | -1.3 | 1.3 | 1.5 | -1.2 | 1.3 | 1.1 | 1.2 | -1.3 | -1.3 | -1.5 | -1.2 | -1.2 | 1.5 | 1.2 | -1.3 | 1.2 | 1.4 | -1.4 | -1.2 | -1.3 | -1.4 | 1.2 | -1.2 | -1.3 | 1.3 | 1.5 |
Pavlov. Cond. index score | 1.5 | 2.0 | 2.4 | -1.4 | 1.4 | 1.5 | -1.4 | 1.5 | 1.3 | 1.3 | -1.4 | -1.4 | -1.5 | -1.3 | -1.4 | 1.3 | 1.4 | -1.4 | 1.4 | 1.5 | -1.5 | -1.4 | -1.4 | -1.6 | 1.4 | -1.4 | -1.4 | 1.4 | 1.5 |
Pavlov. Cond. lever-magazine prob. diff. | 1.5 | 1.9 | 2.3 | -1.4 | 1.4 | 1.5 | -1.4 | 1.4 | 1.2 | 1.3 | -1.4 | -1.4 | -1.5 | -1.3 | -1.4 | 1.3 | 1.3 | -1.4 | 1.4 | 1.4 | -1.4 | -1.3 | -1.4 | -1.5 | 1.4 | -1.4 | -1.4 | 1.4 | 1.5 |
Intermitt. access day 1 inactive lever presses | 1.5 | 1.6 | 2.2 | -1.2 | 1.2 | 1.5 | -1.3 | 1.2 | 0.8 | 1.1 | -1.2 | -1.3 | -1.5 | -1.1 | -1.3 | 1.4 | 1.1 | -1.2 | 1.2 | 1.4 | -1.4 | -1.2 | -1.3 | -1.4 | 1.3 | -1.3 | -1.2 | 1.2 | 1.5 |
Bone: post-yield work | 1.5 | 2.0 | 2.4 | -1.5 | 1.5 | 1.3 | -1.5 | 1.5 | 1.5 | 1.5 | -1.5 | -1.5 | -1.3 | -1.5 | -1.6 | 0.8 | 1.5 | -1.5 | 1.4 | 1.3 | -1.3 | -1.5 | -1.5 | -1.3 | 1.5 | -1.5 | -1.5 | 1.5 | 1.3 |
Conditioned reinforcement - inactives | 1.4 | 1.5 | 2.0 | 1.3 | -1.3 | -1.4 | 1.3 | -1.4 | -1.3 | -1.0 | 1.1 | 1.2 | 1.4 | 1.2 | 0.9 | -0.4 | -1.4 | 1.1 | -1.4 | -1.3 | 1.3 | 1.1 | 1.3 | 1.4 | -1.3 | 1.3 | 1.1 | -1.1 | -1.4 |
Time in novel zone, NPP test | 1.4 | 1.4 | 2.2 | -1.2 | 1.2 | 1.3 | -1.2 | 1.2 | 1.1 | 1.1 | -1.2 | -1.2 | -1.2 | -1.2 | -1.1 | 0.4 | 1.2 | -1.2 | 1.2 | 1.5 | -1.5 | -1.2 | -1.2 | -1.5 | 1.2 | -1.2 | -1.2 | 1.2 | 1.1 |
Bone: minimum diameter | 1.4 | 2.6 | 3.2 | -1.5 | 1.5 | 1.7 | -1.5 | 1.5 | 1.7 | 1.7 | -1.7 | -1.7 | -1.7 | -1.6 | -1.8 | 1.6 | 1.5 | -1.7 | 1.5 | 1.6 | -1.6 | -1.7 | -1.6 | -1.6 | 1.5 | -1.5 | -1.7 | 1.7 | 1.7 |
Time to tail flick, vehicle, before self-admin | 1.4 | 1.4 | 2.7 | -0.9 | 0.9 | 1.1 | -1.0 | 0.9 | 1.5 | 1.4 | -1.3 | -1.2 | -1.1 | -1.1 | -1.5 | 1.6 | 1.1 | -1.3 | 0.9 | 1.1 | -1.1 | -1.3 | -1.2 | -1.1 | 1.0 | -1.0 | -1.3 | 1.3 | 1.1 |
Delay discounting total patch changes 24 sec | 1.3 | 1.6 | 2.4 | -1.3 | 1.3 | 1.1 | -1.3 | 1.0 | 1.4 | 1.4 | -1.3 | -1.3 | -1.1 | -1.3 | -1.6 | 0.8 | 1.5 | -1.3 | 1.4 | 1.1 | -1.1 | -1.3 | -1.2 | -1.1 | 1.3 | -1.3 | -1.3 | 1.3 | 1.1 |
Locomotor testing distance | 1.3 | 2.1 | 2.4 | -1.3 | 1.3 | 1.4 | -1.3 | 1.5 | 1.6 | 1.5 | -1.5 | -1.5 | -1.4 | -1.5 | -1.5 | 0.8 | 1.6 | -1.5 | 1.5 | 1.5 | -1.5 | -1.5 | -1.5 | -1.4 | 1.5 | -1.5 | -1.5 | 1.5 | 1.4 |
Novel to familiar place preference ratio | 1.3 | 1.3 | 2.0 | -1.1 | 1.1 | 1.2 | -1.1 | 1.2 | 1.1 | 1.1 | -1.1 | -1.2 | -1.1 | -1.2 | -1.1 | 0.4 | 1.2 | -1.1 | 1.2 | 1.4 | -1.4 | -1.1 | -1.2 | -1.4 | 1.2 | -1.2 | -1.1 | 1.1 | 1.1 |
Locomotion in novel chamber | 1.3 | 1.6 | 2.0 | -1.4 | 1.4 | 1.0 | -1.4 | 1.4 | 1.3 | 1.4 | -1.3 | -1.3 | -0.9 | -1.4 | -1.3 | -0.8 | 1.4 | -1.3 | 1.4 | 1.2 | -1.2 | -1.4 | -1.3 | -1.1 | 1.4 | -1.4 | -1.3 | 1.3 | 0.9 |
Cd content in liver | 1.3 | 1.4 | 1.7 | -1.1 | 1.1 | 1.3 | -1.1 | 1.1 | 1.2 | 1.2 | -1.2 | -1.2 | -1.3 | -1.1 | -1.2 | 1.2 | 1.1 | -1.2 | 1.1 | 1.3 | -1.3 | -1.2 | -1.2 | -1.3 | 1.1 | -1.1 | -1.2 | 1.2 | 1.3 |
Social response proportion | 1.2 | 1.3 | 1.7 | -1.1 | 1.1 | 1.3 | -1.1 | 1.1 | 0.9 | 1.0 | -1.1 | -1.2 | -1.3 | -1.2 | -0.8 | 0.4 | 1.3 | -1.1 | 1.2 | 1.3 | -1.3 | -1.1 | -1.2 | -1.3 | 1.2 | -1.2 | -1.1 | 1.1 | 1.3 |
Pavlov. Cond. lever latency | 1.2 | 1.6 | 2.2 | 1.2 | -1.2 | -1.4 | 1.2 | -1.3 | -1.1 | -1.1 | 1.2 | 1.3 | 1.4 | 1.1 | 1.2 | -1.3 | -1.2 | 1.2 | -1.3 | -1.4 | 1.4 | 1.2 | 1.3 | 1.5 | -1.2 | 1.2 | 1.2 | -1.2 | -1.4 |
Pavlov. Cond. latency score | 1.2 | 1.6 | 1.9 | -1.2 | 1.2 | 1.3 | -1.2 | 1.3 | 1.1 | 1.2 | -1.2 | -1.3 | -1.3 | -1.1 | -1.2 | 1.1 | 1.2 | -1.2 | 1.2 | 1.3 | -1.3 | -1.2 | -1.3 | -1.4 | 1.2 | -1.2 | -1.2 | 1.2 | 1.3 |
Pavlov. Cond. intertrial magazine entries | 1.2 | 1.6 | 2.0 | 1.3 | -1.3 | -1.3 | 1.3 | -1.3 | -1.2 | -1.2 | 1.3 | 1.3 | 1.4 | 1.2 | 1.2 | -1.2 | -1.3 | 1.3 | -1.3 | -1.2 | 1.2 | 1.3 | 1.3 | 1.2 | -1.3 | 1.3 | 1.3 | -1.3 | -1.4 |
Degree of sensitization stereotypy | 1.2 | 1.4 | 1.6 | -1.2 | 1.2 | 1.2 | -1.2 | 1.2 | 1.2 | 1.2 | -1.2 | -1.2 | -1.2 | -1.1 | -1.2 | 0.9 | 1.2 | -1.2 | 1.2 | 1.1 | -1.1 | -1.2 | -1.2 | -1.1 | 1.2 | -1.2 | -1.2 | 1.2 | 1.2 |
Bone: endosteal perimeter | 1.2 | 2.5 | 3.0 | -1.6 | 1.6 | 1.5 | -1.6 | 1.6 | 1.6 | 1.7 | -1.6 | -1.6 | -1.5 | -1.6 | -1.7 | 0.9 | 1.6 | -1.6 | 1.6 | 1.5 | -1.5 | -1.7 | -1.6 | -1.5 | 1.6 | -1.6 | -1.6 | 1.6 | 1.5 |
Condit. Reinf. active minus inactive responses | 1.1 | 1.3 | 1.7 | 1.2 | -1.2 | -1.0 | 1.2 | -1.2 | -1.3 | -1.3 | 1.2 | 1.2 | 1.0 | 1.3 | 1.3 | -0.2 | -1.3 | 1.2 | -1.2 | -0.9 | 0.9 | 1.2 | 1.2 | 0.8 | -1.3 | 1.3 | 1.2 | -1.2 | -1.0 |
Time in novel zone, hab. session 2 | 1.1 | 1.1 | 1.3 | -1.1 | 1.1 | 1.0 | -1.1 | 1.1 | 1.1 | 1.1 | -1.1 | -1.1 | -1.0 | -1.1 | -1.1 | 0.4 | 1.1 | -1.1 | 1.1 | 1.1 | -1.1 | -1.1 | -1.1 | -1.1 | 1.1 | -1.1 | -1.1 | 1.1 | 1.0 |
Bone: elastic work | 1.1 | 1.5 | 1.8 | 1.3 | -1.3 | -1.1 | 1.3 | -1.3 | -1.2 | -1.3 | 1.3 | 1.2 | 1.1 | 1.3 | 1.3 | -0.3 | -1.3 | 1.3 | -1.3 | -1.0 | 1.0 | 1.3 | 1.2 | 1.0 | -1.3 | 1.3 | 1.3 | -1.3 | -1.1 |
Delay discount hyperbolic model param | 1.1 | 1.1 | 1.7 | -0.9 | 0.9 | 1.3 | -0.9 | 1.2 | 0.8 | 0.9 | -1.0 | -1.1 | -1.3 | -0.9 | -0.8 | 1.3 | 0.9 | -1.0 | 0.8 | 1.3 | -1.3 | -1.0 | -1.1 | -1.2 | 0.9 | -0.9 | -1.0 | 1.0 | 1.3 |
Condit. Reinf. active responses | 1.0 | 1.3 | 1.6 | 1.2 | -1.2 | -1.1 | 1.2 | -1.1 | -1.3 | -1.2 | 1.2 | 1.2 | 1.2 | 1.3 | 1.2 | -0.8 | -1.2 | 1.2 | -1.2 | -1.0 | 1.0 | 1.2 | 1.2 | 0.9 | -1.2 | 1.2 | 1.2 | -1.2 | -1.2 |
Intermittent access intake day 1-15 change | 1.0 | 1.0 | 1.8 | 1.0 | -1.0 | -1.2 | 1.0 | -1.0 | -0.7 | -0.8 | 0.9 | 0.9 | 1.3 | 0.8 | 0.8 | -1.3 | -0.9 | 0.9 | -0.9 | -1.0 | 1.0 | 0.8 | 1.0 | 1.1 | -1.0 | 1.0 | 0.9 | -0.9 | -1.3 |
Intermittent access intake escalation | 1.0 | 1.0 | 3.5 | 0.9 | -0.9 | -1.3 | 0.9 | -0.8 | -0.6 | -0.6 | 0.8 | 0.9 | 1.4 | 0.7 | 0.8 | -1.9 | -0.8 | 0.8 | -0.7 | -1.1 | 1.1 | 0.8 | 1.0 | 1.1 | -0.8 | 0.8 | 0.8 | -0.8 | -1.4 |
Intermitt. access day 15 inactive lever presses | 1.0 | 1.2 | 2.0 | 1.3 | -1.3 | -0.8 | 1.2 | -1.2 | -1.4 | -1.1 | 1.1 | 1.0 | 0.8 | 1.3 | 1.0 | 0.4 | -1.2 | 1.1 | -1.3 | -0.8 | 0.8 | 1.0 | 1.1 | 0.8 | -1.2 | 1.2 | 1.1 | -1.1 | -0.8 |
Stereotopy head waving bouts, day 7 | 1.0 | 1.1 | 1.4 | -1.1 | 1.1 | 1.0 | -1.1 | 1.1 | 1.2 | 1.2 | -1.1 | -1.1 | -1.0 | -1.1 | -1.2 | 0.5 | 1.1 | -1.1 | 1.1 | 0.9 | -0.9 | -1.1 | -1.1 | -0.9 | 1.1 | -1.1 | -1.1 | 1.1 | 1.0 |
Distance moved, locomotor task time 2 | 1.0 | 1.2 | 2.7 | 0.8 | -0.8 | -1.1 | 0.8 | -1.1 | -1.3 | -1.1 | 1.1 | 1.1 | 1.0 | 0.8 | 1.5 | -1.7 | -0.8 | 1.1 | -0.8 | -1.2 | 1.2 | 1.2 | 1.0 | 1.2 | -0.9 | 0.9 | 1.1 | -1.1 | -1.0 |
Se content in liver | 1.0 | 1.1 | 1.4 | -1.1 | 1.1 | 1.0 | -1.1 | 1.1 | 1.1 | 1.1 | -1.1 | -1.1 | -1.0 | -1.0 | -1.2 | 0.7 | 1.0 | -1.1 | 1.1 | 1.0 | -1.0 | -1.1 | -1.1 | -1.1 | 1.1 | -1.1 | -1.1 | 1.1 | 1.0 |
Zn content in liver | 1.0 | 1.1 | 1.3 | -1.0 | 1.0 | 1.1 | -1.0 | 1.0 | 1.0 | 1.0 | -1.0 | -1.0 | -1.1 | -1.0 | -1.0 | 0.9 | 1.0 | -1.0 | 1.0 | 1.0 | -1.0 | -1.0 | -1.1 | -1.1 | 1.0 | -1.0 | -1.0 | 1.0 | 1.1 |
Median of all reaction times | 0.9 | 1.2 | 1.8 | -1.3 | 1.3 | 1.1 | -1.3 | 1.3 | 0.9 | 1.0 | -1.1 | -1.1 | -1.1 | -1.1 | -0.8 | 0.1 | 1.1 | -1.1 | 1.3 | 1.2 | -1.2 | -1.0 | -1.2 | -1.1 | 1.2 | -1.2 | -1.1 | 1.1 | 1.1 |
Intermittent access standard deviation | 0.9 | 1.0 | 1.2 | 1.0 | -1.0 | -1.0 | 1.0 | -0.9 | -1.0 | -1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.1 | -1.0 | -0.9 | 1.0 | -1.0 | -1.0 | 1.0 | 1.0 | 1.0 | 1.0 | -1.0 | 1.0 | 1.0 | -1.0 | -1.0 |
Post-drug Anxiety | 0.9 | 1.0 | 1.5 | 0.9 | -0.9 | -1.0 | 0.9 | -0.8 | -1.2 | -1.1 | 1.1 | 1.0 | 1.0 | 1.2 | 1.1 | -0.6 | -1.0 | 1.0 | -1.0 | -1.1 | 1.1 | 1.1 | 1.0 | 1.0 | -0.9 | 0.9 | 1.0 | -1.1 | -1.0 |
Stereotopy head waving duration, day 7 | 0.9 | 1.1 | 1.4 | -1.1 | 1.1 | 0.8 | -1.1 | 1.1 | 1.2 | 1.2 | -1.1 | -1.1 | -0.8 | -1.1 | -1.2 | 0.1 | 1.1 | -1.1 | 1.1 | 0.8 | -0.8 | -1.1 | -1.0 | -0.8 | 1.1 | -1.1 | -1.1 | 1.1 | 0.8 |
Locomotion distance, session 8 | 0.9 | 1.3 | 1.5 | 1.1 | -1.1 | -1.1 | 1.1 | -1.2 | -1.1 | -1.1 | 1.1 | 1.1 | 1.1 | 1.2 | 1.1 | -0.3 | -1.2 | 1.1 | -1.2 | -1.1 | 1.1 | 1.1 | 1.2 | 1.1 | -1.2 | 1.2 | 1.1 | -1.1 | -1.1 |
Novelty place preference | 0.9 | 1.0 | 1.5 | -1.0 | 1.0 | 1.0 | -1.0 | 1.0 | 0.9 | 0.9 | -1.0 | -1.0 | -0.9 | -1.0 | -0.9 | 0.2 | 1.0 | -1.0 | 1.0 | 1.2 | -1.2 | -0.9 | -1.0 | -1.2 | 1.0 | -1.0 | -1.0 | 1.0 | 0.9 |
Breakpoint value in progressive ratio session | 0.9 | 1.0 | 2.5 | 0.7 | -0.7 | -1.4 | 0.7 | -1.1 | -0.3 | -0.5 | 0.8 | 1.0 | 1.4 | 0.8 | 0.3 | -1.0 | -0.5 | 0.8 | -0.6 | -1.6 | 1.6 | 0.7 | 1.1 | 1.5 | -0.9 | 0.9 | 0.9 | -0.8 | -1.4 |
Delta time in open arm before/after self-admin | 0.9 | 0.9 | 1.7 | -0.9 | 0.9 | 0.9 | -0.9 | 1.0 | 0.8 | 1.0 | -1.0 | -1.0 | -0.8 | -1.0 | -1.3 | 1.1 | 0.7 | -1.0 | 0.8 | 1.0 | -1.0 | -1.0 | -0.9 | -0.9 | 0.9 | -0.9 | -1.0 | 1.0 | 0.8 |
Area under the delay curve | 0.9 | 0.9 | 1.4 | 0.9 | -0.9 | -1.1 | 0.8 | -1.1 | -0.8 | -0.8 | 0.9 | 1.0 | 1.2 | 0.8 | 0.7 | -1.1 | -0.8 | 0.9 | -0.8 | -1.2 | 1.2 | 0.9 | 1.0 | 1.1 | -0.8 | 0.8 | 0.9 | -0.9 | -1.2 |
Delay discount exponential model param | 0.9 | 0.9 | 1.4 | -0.9 | 0.9 | 1.2 | -0.8 | 1.1 | 0.8 | 0.8 | -0.9 | -1.0 | -1.2 | -0.8 | -0.7 | 1.1 | 0.8 | -0.9 | 0.8 | 1.2 | -1.2 | -0.9 | -1.0 | -1.1 | 0.9 | -0.9 | -1.0 | 0.9 | 1.2 |
Reaction time omissions | 0.8 | 1.1 | 1.9 | -1.0 | 1.0 | 1.3 | -1.0 | 1.0 | 0.9 | 0.8 | -1.0 | -1.1 | -1.3 | -0.9 | -0.6 | 1.2 | 1.0 | -1.0 | 1.1 | 1.4 | -1.4 | -0.9 | -1.1 | -1.4 | 0.9 | -0.9 | -1.0 | 1.0 | 1.3 |
Reaction time false alarm rate | 0.8 | 1.2 | 1.5 | -1.1 | 1.1 | 1.1 | -1.1 | 1.2 | 0.8 | 1.0 | -1.0 | -1.0 | -1.1 | -0.9 | -1.1 | 1.2 | 1.1 | -1.0 | 1.1 | 1.2 | -1.2 | -1.0 | -1.0 | -1.1 | 1.1 | -1.1 | -1.0 | 1.0 | 1.1 |
Intermittent access intake escalation 2 | 0.8 | 0.8 | 2.8 | 0.9 | -0.9 | -1.1 | 0.9 | -0.8 | -0.5 | -0.6 | 0.8 | 0.8 | 1.2 | 0.6 | 0.8 | -1.7 | -0.7 | 0.8 | -0.7 | -1.0 | 1.0 | 0.7 | 0.9 | 1.0 | -0.8 | 0.8 | 0.8 | -0.8 | -1.2 |
Pavlov. Cond. magazine entry number | 0.8 | 0.9 | 1.2 | -1.0 | 1.0 | 0.8 | -1.0 | 1.1 | 1.1 | 1.1 | -1.0 | -1.0 | -0.8 | -1.0 | -1.0 | 0.1 | 1.0 | -1.0 | 1.0 | 0.9 | -0.9 | -1.0 | -1.0 | -0.9 | 1.0 | -1.0 | -1.0 | 1.0 | 0.8 |
Total heroin consumption | 0.8 | 1.0 | 2.6 | 0.9 | -0.9 | -1.2 | 0.7 | -1.1 | -0.9 | -0.8 | 0.9 | 1.0 | 1.2 | 0.8 | 0.9 | -1.6 | -0.5 | 0.9 | -0.6 | -1.2 | 1.2 | 0.9 | 1.0 | 1.2 | -0.9 | 0.9 | 0.9 | -0.9 | -1.2 |
Total resting periods, locomotor time 2 | 0.8 | 0.9 | 1.8 | -0.7 | 0.7 | 1.1 | -0.7 | 1.0 | 0.7 | 0.8 | -0.9 | -0.9 | -1.1 | -0.7 | -0.8 | 1.3 | 0.7 | -0.9 | 0.7 | 1.1 | -1.1 | -0.9 | -1.0 | -1.1 | 0.8 | -0.8 | -0.9 | 0.9 | 1.1 |
Fe content in liver | 0.8 | 0.9 | 1.1 | -1.0 | 1.0 | 1.1 | -1.0 | 0.9 | 0.9 | 0.9 | -1.0 | -1.0 | -1.1 | -0.9 | -0.9 | 1.0 | 0.9 | -1.0 | 1.0 | 1.1 | -1.1 | -0.9 | -1.0 | -1.1 | 0.9 | -0.9 | -1.0 | 1.0 | 1.1 |
K content in liver | 0.8 | 0.8 | 1.3 | 0.8 | -0.8 | -1.0 | 0.8 | -0.9 | -0.9 | -0.9 | 0.9 | 0.9 | 1.0 | 0.9 | 0.8 | -0.7 | -0.9 | 0.9 | -0.8 | -1.1 | 1.1 | 0.9 | 0.9 | 1.1 | -0.9 | 0.9 | 0.9 | -0.9 | -1.0 |
Tail length | 0.7 | 2.2 | 3.1 | 1.6 | -1.6 | -1.7 | 1.6 | -1.5 | -0.9 | -1.1 | 1.3 | 1.4 | 1.7 | 1.4 | 1.2 | -0.5 | -1.6 | 1.3 | -1.8 | -1.7 | 1.7 | 1.3 | 1.5 | 1.6 | -1.6 | 1.6 | 1.3 | -1.3 | -1.7 |
Reaction time mean | 0.7 | 1.0 | 1.5 | -1.2 | 1.2 | 0.9 | -1.2 | 1.2 | 0.9 | 1.0 | -1.0 | -1.0 | -0.9 | -1.1 | -0.8 | -0.2 | 1.0 | -1.0 | 1.2 | 1.0 | -1.0 | -1.0 | -1.0 | -1.0 | 1.1 | -1.1 | -1.0 | 1.0 | 0.9 |
Reaction time premature initiations | 0.7 | 0.9 | 1.4 | 1.1 | -1.1 | -0.9 | 1.1 | -1.0 | -0.8 | -1.0 | 0.9 | 1.0 | 0.8 | 1.1 | 0.7 | 0.7 | -1.2 | 1.0 | -1.0 | -1.0 | 1.0 | 0.9 | 1.0 | 0.9 | -1.1 | 1.1 | 1.0 | -1.0 | -0.8 |
Locomotion distance, session 1 | 0.7 | 0.9 | 1.1 | 0.9 | -0.9 | -1.1 | 0.9 | -1.0 | -0.9 | -0.9 | 1.0 | 1.0 | 1.1 | 0.9 | 0.9 | -0.8 | -1.0 | 1.0 | -1.0 | -1.1 | 1.1 | 0.9 | 1.0 | 1.1 | -1.0 | 1.0 | 1.0 | -1.0 | -1.1 |
Stereotopy head waving duration, day 3 | 0.7 | 0.9 | 1.1 | 1.0 | -1.0 | -1.0 | 0.9 | -0.9 | -0.9 | -0.9 | 0.9 | 1.0 | 1.0 | 0.9 | 0.9 | -0.9 | -0.9 | 0.9 | -0.9 | -1.0 | 1.0 | 0.9 | 1.0 | 1.0 | -0.9 | 0.9 | 0.9 | -0.9 | -1.0 |
Bouts of movement, locomotor time 2 | 0.7 | 0.7 | 1.8 | -0.7 | 0.7 | 1.1 | -0.7 | 0.9 | 0.6 | 0.7 | -0.8 | -0.9 | -1.1 | -0.6 | -0.8 | 1.3 | 0.7 | -0.8 | 0.7 | 1.0 | -1.0 | -0.8 | -0.9 | -1.0 | 0.8 | -0.8 | -0.9 | 0.8 | 1.1 |
Rest time, locomotor task time 2 | 0.7 | 0.8 | 1.4 | -0.7 | 0.7 | 0.8 | -0.8 | 0.8 | 1.2 | 0.9 | -0.9 | -0.9 | -0.8 | -0.8 | -1.1 | 1.1 | 0.8 | -0.9 | 0.8 | 0.8 | -0.8 | -1.0 | -0.9 | -0.8 | 0.8 | -0.8 | -0.9 | 0.9 | 0.8 |
Seeking ratio, punishment vs. effort | 0.7 | 0.8 | 1.3 | 0.8 | -0.8 | -0.8 | 0.8 | -0.8 | -1.1 | -1.1 | 1.0 | 0.9 | 0.7 | 1.1 | 1.1 | -0.6 | -0.9 | 1.0 | -0.9 | -0.7 | 0.7 | 1.0 | 0.9 | 0.9 | -0.9 | 0.9 | 1.0 | -1.0 | -0.7 |
Length with tail | 0.6 | 2.1 | 3.1 | 1.7 | -1.7 | -1.5 | 1.7 | -1.5 | -1.1 | -1.2 | 1.3 | 1.4 | 1.5 | 1.5 | 1.2 | -0.3 | -1.6 | 1.3 | -1.8 | -1.5 | 1.5 | 1.3 | 1.5 | 1.5 | -1.6 | 1.6 | 1.4 | -1.3 | -1.5 |
Extensor digitorum longus weight | 0.6 | 2.5 | 2.7 | 1.6 | -1.6 | -1.6 | 1.6 | -1.6 | -1.6 | -1.6 | 1.6 | 1.6 | 1.6 | 1.5 | 1.6 | -1.1 | -1.6 | 1.6 | -1.6 | -1.5 | 1.5 | 1.6 | 1.6 | 1.6 | -1.6 | 1.6 | 1.6 | -1.6 | -1.6 |
Indifference point AUC | 0.6 | 0.7 | 1.3 | -0.8 | 0.8 | 0.7 | -0.8 | 0.7 | 1.2 | 1.0 | -0.9 | -0.9 | -0.7 | -0.8 | -1.1 | 0.8 | 0.9 | -0.9 | 0.9 | 0.7 | -0.7 | -0.9 | -0.8 | -0.7 | 0.7 | -0.7 | -0.9 | 0.9 | 0.7 |
Delay discounting total patch changes 12 sec | 0.6 | 0.8 | 1.6 | -0.9 | 0.9 | 0.8 | -0.9 | 0.7 | 1.0 | 0.9 | -0.9 | -0.9 | -0.9 | -0.8 | -1.1 | 1.3 | 1.0 | -0.9 | 0.9 | 0.7 | -0.7 | -0.9 | -0.8 | -0.7 | 0.8 | -0.8 | -0.9 | 0.9 | 0.9 |
Reaction time num false alarms AUC | 0.6 | 0.9 | 2.1 | -0.8 | 0.8 | 0.9 | -0.8 | 1.0 | 0.8 | 0.9 | -0.9 | -0.9 | -0.9 | -0.7 | -1.1 | 1.4 | 0.9 | -0.9 | 0.8 | 1.1 | -1.1 | -0.9 | -0.9 | -1.0 | 0.9 | -0.9 | -0.9 | 0.9 | 0.9 |
Cocaine response after cond. corrected | 0.6 | 0.7 | 1.0 | -0.9 | 0.9 | 0.6 | -0.9 | 1.0 | 1.0 | 1.0 | -0.9 | -0.8 | -0.6 | -1.0 | -1.0 | -0.1 | 0.9 | -0.9 | 0.9 | 0.7 | -0.7 | -0.9 | -0.8 | -0.7 | 0.9 | -0.9 | -0.9 | 0.9 | 0.6 |
Stereotopy head waving bouts, day 3 | 0.6 | 0.7 | 1.9 | 0.7 | -0.7 | -1.1 | 0.7 | -0.7 | -0.6 | -0.6 | 0.8 | 0.8 | 1.0 | 0.6 | 0.7 | -1.4 | -0.7 | 0.7 | -0.7 | -1.1 | 1.1 | 0.7 | 0.8 | 1.1 | -0.7 | 0.7 | 0.8 | -0.7 | -1.0 |
Time in familiar zone, hab. session 2 | 0.6 | 0.6 | 0.7 | 0.8 | -0.8 | -0.8 | 0.8 | -0.8 | -0.8 | -0.8 | 0.8 | 0.8 | 0.8 | 0.7 | 0.8 | -0.5 | -0.8 | 0.8 | -0.8 | -0.8 | 0.8 | 0.8 | 0.8 | 0.8 | -0.8 | 0.8 | 0.8 | -0.8 | -0.8 |
Pavlov. Cond. magazine entry latency | 0.6 | 0.8 | 1.0 | 0.9 | -0.9 | -0.8 | 0.9 | -1.0 | -1.0 | -0.9 | 0.9 | 0.9 | 0.8 | 0.9 | 0.9 | -0.4 | -0.9 | 0.9 | -0.9 | -0.8 | 0.8 | 0.9 | 0.9 | 0.8 | -0.9 | 0.9 | 0.9 | -0.9 | -0.8 |
Pavlov. Cond. intertrial magazine entries | 0.6 | 0.8 | 0.9 | 0.9 | -0.9 | -0.8 | 0.9 | -1.0 | -0.9 | -0.9 | 0.9 | 0.9 | 0.8 | 0.9 | 0.9 | -0.4 | -0.9 | 0.9 | -0.9 | -0.9 | 0.9 | 0.9 | 0.9 | 0.9 | -0.9 | 0.9 | 0.9 | -0.9 | -0.8 |
Bone volume | 0.6 | 0.9 | 1.1 | -1.0 | 1.0 | 1.0 | -1.0 | 1.0 | 1.0 | 1.0 | -1.0 | -1.0 | -1.0 | -0.9 | -1.0 | 0.8 | 1.0 | -1.0 | 1.0 | 0.9 | -0.9 | -1.0 | -1.0 | -0.9 | 1.0 | -1.0 | -1.0 | 1.0 | 1.0 |
Bone: cortical porosity | 0.6 | 0.6 | 0.8 | -0.7 | 0.7 | 0.8 | -0.7 | 0.7 | 0.9 | 0.8 | -0.8 | -0.8 | -0.8 | -0.7 | -0.9 | 0.9 | 0.7 | -0.8 | 0.7 | 0.9 | -0.9 | -0.8 | -0.8 | -0.9 | 0.7 | -0.7 | -0.8 | 0.8 | 0.8 |
Bone: elastic displacement | 0.6 | 0.7 | 1.1 | 0.8 | -0.8 | -0.7 | 0.8 | -0.9 | -0.9 | -1.0 | 0.9 | 0.9 | 0.7 | 0.9 | 1.0 | -0.2 | -0.9 | 0.9 | -0.9 | -0.6 | 0.6 | 0.9 | 0.8 | 0.6 | -0.9 | 0.9 | 0.9 | -0.9 | -0.7 |
Bone: endosteal estimation | 0.6 | 1.2 | 1.5 | -1.1 | 1.1 | 1.1 | -1.1 | 1.2 | 1.1 | 1.2 | -1.2 | -1.1 | -1.1 | -1.2 | -1.2 | 0.6 | 1.2 | -1.2 | 1.2 | 1.1 | -1.1 | -1.2 | -1.1 | -1.0 | 1.1 | -1.1 | -1.2 | 1.2 | 1.1 |
Bone: periosteal estimation | 0.6 | 1.2 | 1.5 | -1.0 | 1.0 | 1.1 | -1.0 | 1.0 | 1.1 | 1.1 | -1.1 | -1.1 | -1.1 | -1.1 | -1.2 | 1.0 | 1.1 | -1.1 | 1.1 | 1.1 | -1.1 | -1.1 | -1.1 | -1.1 | 1.0 | -1.0 | -1.1 | 1.1 | 1.1 |
Delta distance traveled before/after self-admin | 0.6 | 0.7 | 1.9 | -0.9 | 0.9 | 0.6 | -0.8 | 0.7 | 1.0 | 0.9 | -0.8 | -0.8 | -0.7 | -0.8 | -1.1 | 1.4 | 0.6 | -0.8 | 0.7 | 0.6 | -0.6 | -0.9 | -0.7 | -0.5 | 0.7 | -0.7 | -0.8 | 0.8 | 0.7 |
Food consumed during 24 hour testing period | 0.5 | 0.6 | 1.8 | 0.5 | -0.5 | -1.0 | 0.5 | -0.4 | -0.6 | -0.5 | 0.7 | 0.7 | 1.1 | 0.6 | 0.5 | -1.3 | -0.6 | 0.6 | -0.5 | -1.0 | 1.0 | 0.6 | 0.7 | 1.0 | -0.5 | 0.5 | 0.7 | -0.6 | -1.1 |
Light reinforcement 1 | 0.5 | 0.9 | 1.4 | 1.1 | -1.1 | -0.8 | 1.1 | -1.2 | -1.0 | -1.0 | 1.0 | 1.0 | 0.8 | 1.0 | 0.8 | 0.2 | -0.9 | 1.0 | -1.1 | -0.9 | 0.9 | 1.0 | 1.0 | 0.9 | -1.1 | 1.1 | 1.0 | -1.0 | -0.8 |
Reaction time premature initiation rate | 0.5 | 0.6 | 1.0 | 0.8 | -0.8 | -0.6 | 0.8 | -0.8 | -0.8 | -0.9 | 0.8 | 0.8 | 0.6 | 1.0 | 0.6 | 0.7 | -0.9 | 0.8 | -0.7 | -0.9 | 0.9 | 0.8 | 0.8 | 0.7 | -0.8 | 0.8 | 0.8 | -0.8 | -0.6 |
Cocaine response after cond. not corrected | 0.5 | 0.6 | 0.8 | -0.9 | 0.9 | 0.4 | -0.9 | 0.9 | 0.9 | 0.9 | -0.8 | -0.7 | -0.4 | -0.9 | -0.8 | -0.6 | 0.9 | -0.8 | 0.8 | 0.5 | -0.5 | -0.8 | -0.7 | -0.5 | 0.9 | -0.9 | -0.8 | 0.8 | 0.4 |
Conditioned reinforcement - actives | 0.5 | 0.5 | 0.7 | 0.6 | -0.6 | -0.8 | 0.5 | -0.7 | -0.5 | -0.5 | 0.6 | 0.7 | 0.8 | 0.7 | 0.5 | -0.5 | -0.8 | 0.6 | -0.7 | -0.7 | 0.7 | 0.6 | 0.7 | 0.8 | -0.7 | 0.7 | 0.6 | -0.6 | -0.8 |
Intermittent access day 15 total infusions | 0.5 | 0.6 | 0.9 | 0.7 | -0.7 | -0.8 | 0.8 | -0.7 | -0.9 | -0.7 | 0.8 | 0.8 | 0.9 | 0.8 | 0.6 | -0.7 | -0.9 | 0.8 | -0.8 | -0.7 | 0.7 | 0.7 | 0.8 | 0.7 | -0.8 | 0.8 | 0.8 | -0.8 | -0.9 |
Number of responses in last shaping day | 0.5 | 0.5 | 0.9 | 0.8 | -0.8 | -0.7 | 0.8 | -0.9 | -0.6 | -0.6 | 0.6 | 0.7 | 0.7 | 0.7 | 0.2 | 0.5 | -0.8 | 0.7 | -0.8 | -0.7 | 0.7 | 0.6 | 0.8 | 0.8 | -0.8 | 0.8 | 0.7 | -0.6 | -0.7 |
Locomotion velocity, session 7 | 0.5 | 0.5 | 1.0 | 0.6 | -0.6 | -0.9 | 0.6 | -0.7 | -0.6 | -0.6 | 0.7 | 0.7 | 0.9 | 0.6 | 0.6 | -1.0 | -0.6 | 0.7 | -0.6 | -1.0 | 1.0 | 0.7 | 0.7 | 1.0 | -0.6 | 0.6 | 0.7 | -0.7 | -0.9 |
Bone: marrow area | 0.5 | 1.1 | 1.4 | -1.0 | 1.0 | 1.0 | -1.0 | 1.1 | 1.1 | 1.1 | -1.1 | -1.1 | -1.0 | -1.1 | -1.2 | 0.6 | 1.1 | -1.1 | 1.1 | 1.0 | -1.0 | -1.1 | -1.1 | -1.0 | 1.1 | -1.1 | -1.1 | 1.1 | 1.0 |
Bone: maximum diameter | 0.5 | 0.8 | 1.1 | -0.8 | 0.8 | 1.0 | -0.8 | 0.8 | 0.9 | 0.9 | -1.0 | -0.9 | -1.0 | -1.0 | -1.0 | 0.9 | 0.9 | -0.9 | 0.9 | 0.9 | -0.9 | -1.0 | -0.9 | -0.9 | 0.9 | -0.9 | -0.9 | 0.9 | 1.0 |
Bone: periosteal perimeter | 0.5 | 0.8 | 1.0 | -0.8 | 0.8 | 0.9 | -0.8 | 0.8 | 0.9 | 0.9 | -0.9 | -0.9 | -1.0 | -0.9 | -1.0 | 1.0 | 0.8 | -0.9 | 0.8 | 0.9 | -0.9 | -0.9 | -0.9 | -0.9 | 0.8 | -0.8 | -0.9 | 0.9 | 1.0 |
Bone: tissue strength | 0.5 | 0.5 | 0.6 | -0.7 | 0.7 | 0.6 | -0.7 | 0.7 | 0.8 | 0.7 | -0.7 | -0.7 | -0.6 | -0.7 | -0.7 | 0.4 | 0.7 | -0.7 | 0.7 | 0.7 | -0.7 | -0.7 | -0.7 | -0.6 | 0.7 | -0.7 | -0.7 | 0.7 | 0.6 |
Diff in mean of infusions in LGA sessions | 0.5 | 0.6 | 1.1 | 0.7 | -0.7 | -1.0 | 0.6 | -1.0 | -0.4 | -0.5 | 0.6 | 0.7 | 1.0 | 0.7 | 0.5 | -0.3 | -0.6 | 0.6 | -0.6 | -1.0 | 1.0 | 0.6 | 0.8 | 0.9 | -0.8 | 0.8 | 0.6 | -0.6 | -1.0 |
Extinction: sum of active levers before priming | 0.5 | 0.5 | 1.2 | 0.6 | -0.6 | -0.8 | 0.6 | -0.8 | -0.5 | -0.5 | 0.6 | 0.7 | 0.8 | 0.6 | 0.3 | -0.1 | -0.5 | 0.6 | -0.5 | -1.1 | 1.1 | 0.6 | 0.7 | 1.0 | -0.7 | 0.7 | 0.6 | -0.6 | -0.8 |
Delay disc. indifference point, 2s delay | 0.5 | 0.5 | 3.1 | 0.5 | -0.5 | -0.9 | 0.4 | -0.8 | -0.5 | -0.5 | 0.6 | 0.7 | 0.9 | 0.4 | 0.6 | -1.8 | -0.4 | 0.6 | -0.4 | -0.9 | 0.9 | 0.6 | 0.7 | 0.8 | -0.4 | 0.4 | 0.6 | -0.6 | -0.9 |
Mg content in liver | 0.5 | 0.5 | 0.7 | -0.8 | 0.8 | 0.6 | -0.8 | 0.7 | 0.8 | 0.8 | -0.8 | -0.7 | -0.6 | -0.8 | -0.8 | 0.1 | 0.8 | -0.8 | 0.8 | 0.5 | -0.5 | -0.8 | -0.7 | -0.6 | 0.8 | -0.8 | -0.8 | 0.8 | 0.6 |
Rb content in liver | 0.5 | 0.7 | 1.0 | 0.7 | -0.7 | -0.9 | 0.7 | -0.9 | -0.8 | -0.8 | 0.8 | 0.8 | 0.9 | 0.6 | 0.8 | -0.9 | -0.7 | 0.8 | -0.7 | -1.0 | 1.0 | 0.8 | 0.8 | 1.0 | -0.8 | 0.8 | 0.8 | -0.8 | -0.9 |
Left kidney weight | 0.4 | 1.3 | 2.1 | 0.9 | -0.9 | -1.4 | 1.0 | -0.9 | -0.9 | -1.0 | 1.1 | 1.1 | 1.5 | 1.2 | 1.0 | -1.3 | -1.2 | 1.1 | -1.1 | -1.2 | 1.2 | 1.0 | 1.1 | 1.3 | -1.0 | 1.0 | 1.1 | -1.1 | -1.5 |
Right kidney weight | 0.4 | 1.0 | 2.3 | 0.8 | -0.8 | -1.4 | 0.9 | -0.7 | -0.5 | -0.7 | 0.9 | 0.9 | 1.4 | 1.0 | 0.9 | -1.5 | -1.0 | 0.9 | -0.9 | -1.1 | 1.1 | 0.9 | 1.0 | 1.2 | -0.8 | 0.8 | 0.9 | -0.9 | -1.4 |
Social responses | 0.4 | 0.5 | 0.9 | 0.9 | -0.9 | -0.3 | 0.9 | -0.9 | -0.8 | -0.9 | 0.7 | 0.7 | 0.3 | 0.9 | 0.9 | 0.8 | -0.7 | 0.8 | -0.9 | -0.3 | 0.3 | 0.8 | 0.6 | 0.3 | -0.9 | 0.9 | 0.7 | -0.8 | -0.3 |
Condit. Reinf. lever reinforcers received | 0.4 | 0.5 | 0.7 | 0.7 | -0.7 | -0.7 | 0.7 | -0.6 | -0.8 | -0.8 | 0.7 | 0.7 | 0.8 | 0.8 | 0.8 | -0.6 | -0.7 | 0.7 | -0.7 | -0.5 | 0.5 | 0.8 | 0.7 | 0.5 | -0.7 | 0.7 | 0.7 | -0.7 | -0.8 |
Pavlov. Cond. magazine entry number | 0.4 | 0.5 | 1.8 | 0.6 | -0.6 | -0.9 | 0.6 | -0.7 | -0.5 | -0.5 | 0.6 | 0.7 | 1.0 | 0.5 | 0.6 | -1.3 | -0.6 | 0.6 | -0.6 | -0.8 | 0.8 | 0.6 | 0.7 | 0.9 | -0.6 | 0.6 | 0.6 | -0.6 | -1.0 |
Baseline Anxiety | 0.4 | 0.4 | 2.3 | 0.6 | -0.6 | -0.7 | 0.5 | -0.5 | -0.6 | -0.6 | 0.6 | 0.6 | 0.8 | 0.5 | 0.9 | -1.5 | -0.4 | 0.6 | -0.4 | -0.6 | 0.6 | 0.7 | 0.6 | 0.8 | -0.5 | 0.5 | 0.6 | -0.6 | -0.8 |
Progressive ratio test 2 breakpoint | 0.4 | 0.4 | 0.9 | 0.7 | -0.7 | -0.6 | 0.7 | -0.8 | -0.6 | -0.5 | 0.6 | 0.6 | 0.6 | 0.8 | 0.4 | 0.5 | -0.9 | 0.6 | -0.8 | -0.5 | 0.5 | 0.5 | 0.7 | 0.7 | -0.8 | 0.8 | 0.6 | -0.6 | -0.6 |
Progressive ratio test 2 inactive lever presses | 0.4 | 0.4 | 0.7 | 0.8 | -0.8 | -0.6 | 0.8 | -0.8 | -0.7 | -0.5 | 0.5 | 0.6 | 0.6 | 0.7 | 0.3 | 0.4 | -0.9 | 0.6 | -0.8 | -0.6 | 0.6 | 0.5 | 0.7 | 0.7 | -0.8 | 0.8 | 0.6 | -0.6 | -0.6 |
Short access day 10 total infusions | 0.4 | 0.5 | 2.3 | 0.8 | -0.8 | -0.5 | 0.8 | -0.7 | -0.6 | -0.6 | 0.5 | 0.6 | 0.5 | 0.8 | 0.1 | 1.5 | -1.0 | 0.6 | -1.0 | -0.5 | 0.5 | 0.5 | 0.7 | 0.5 | -0.8 | 0.8 | 0.6 | -0.6 | -0.5 |
Short access day 10 total locomotion | 0.4 | 0.4 | 0.9 | -0.6 | 0.6 | 0.7 | -0.6 | 0.6 | 0.5 | 0.5 | -0.6 | -0.6 | -0.7 | -0.6 | -0.6 | 1.0 | 0.5 | -0.6 | 0.5 | 0.7 | -0.7 | -0.6 | -0.6 | -0.7 | 0.5 | -0.5 | -0.6 | 0.6 | 0.7 |
Locomotion velocity, session 8 | 0.4 | 0.5 | 0.6 | 0.7 | -0.7 | -0.7 | 0.7 | -0.7 | -0.8 | -0.7 | 0.7 | 0.7 | 0.6 | 0.7 | 0.8 | -0.3 | -0.7 | 0.7 | -0.7 | -0.8 | 0.8 | 0.7 | 0.7 | 0.8 | -0.7 | 0.7 | 0.7 | -0.7 | -0.6 |
Locomotion velocity, NPP test | 0.4 | 0.6 | 0.9 | 0.7 | -0.7 | -0.9 | 0.7 | -0.7 | -0.5 | -0.6 | 0.7 | 0.7 | 1.0 | 0.7 | 0.5 | -0.9 | -0.7 | 0.7 | -0.7 | -0.9 | 0.9 | 0.7 | 0.8 | 0.9 | -0.7 | 0.7 | 0.7 | -0.7 | -0.9 |
Bone: cortical porosity | 0.4 | 0.4 | 0.5 | -0.6 | 0.6 | 0.6 | -0.6 | 0.6 | 0.7 | 0.7 | -0.7 | -0.7 | -0.6 | -0.6 | -0.7 | 0.5 | 0.6 | -0.7 | 0.6 | 0.7 | -0.7 | -0.7 | -0.7 | -0.7 | 0.6 | -0.6 | -0.7 | 0.7 | 0.6 |
Bone: final force | 0.4 | 0.6 | 0.8 | 0.8 | -0.8 | -0.8 | 0.8 | -0.8 | -0.7 | -0.7 | 0.8 | 0.8 | 0.8 | 0.7 | 0.7 | -0.5 | -0.7 | 0.8 | -0.8 | -0.9 | 0.9 | 0.8 | 0.8 | 0.9 | -0.8 | 0.8 | 0.8 | -0.8 | -0.8 |
Ambulatory time before self-admin | 0.4 | 0.4 | 0.9 | 0.7 | -0.7 | -0.8 | 0.5 | -1.0 | -0.1 | -0.4 | 0.5 | 0.6 | 0.8 | 0.4 | 0.4 | -0.3 | -0.4 | 0.5 | -0.3 | -0.9 | 0.9 | 0.5 | 0.7 | 0.8 | -0.7 | 0.7 | 0.5 | -0.5 | -0.8 |
Retroperitoneal fat weight | 0.3 | 0.9 | 1.6 | 0.9 | -0.9 | -1.0 | 1.0 | -1.0 | -0.8 | -0.8 | 0.9 | 0.9 | 1.1 | 1.0 | 1.1 | -1.3 | -1.0 | 0.9 | -0.9 | -0.9 | 0.9 | 0.9 | 0.9 | 1.0 | -0.9 | 0.9 | 0.9 | -0.9 | -1.1 |
Reaction time mean AUC | 0.3 | 0.4 | 0.7 | -0.8 | 0.8 | 0.5 | -0.8 | 0.9 | 0.5 | 0.6 | -0.6 | -0.6 | -0.5 | -0.7 | -0.5 | -0.5 | 0.7 | -0.6 | 0.9 | 0.6 | -0.6 | -0.6 | -0.6 | -0.6 | 0.7 | -0.7 | -0.6 | 0.6 | 0.5 |
Condit. Reinf. active-inactive response ratio | 0.3 | 0.3 | 0.6 | 0.7 | -0.7 | -0.3 | 0.7 | -0.7 | -0.7 | -0.7 | 0.6 | 0.5 | 0.3 | 0.7 | 0.7 | 0.4 | -0.7 | 0.6 | -0.7 | -0.3 | 0.3 | 0.6 | 0.5 | 0.2 | -0.7 | 0.7 | 0.6 | -0.6 | -0.3 |
Conditioned locomotion | 0.3 | 0.3 | 0.7 | 0.5 | -0.5 | -0.5 | 0.4 | -0.6 | -0.5 | -0.6 | 0.6 | 0.6 | 0.5 | 0.6 | 0.3 | 0.2 | -0.8 | 0.6 | -0.8 | -0.6 | 0.6 | 0.5 | 0.6 | 0.6 | -0.6 | 0.6 | 0.6 | -0.6 | -0.5 |
Intermittent access total infusions | 0.3 | 0.3 | 0.6 | 0.4 | -0.4 | -0.5 | 0.5 | -0.5 | -0.8 | -0.6 | 0.6 | 0.6 | 0.5 | 0.7 | 0.5 | 0.0 | -0.7 | 0.6 | -0.7 | -0.4 | 0.4 | 0.6 | 0.6 | 0.4 | -0.6 | 0.6 | 0.6 | -0.6 | -0.5 |
Intermittent access day 1 locomotion | 0.3 | 0.3 | 2.6 | -0.5 | 0.5 | 0.7 | -0.4 | 0.5 | -0.1 | 0.2 | -0.3 | -0.4 | -0.7 | -0.2 | -0.5 | 1.6 | 0.1 | -0.3 | 0.1 | 0.7 | -0.7 | -0.3 | -0.4 | -0.7 | 0.3 | -0.3 | -0.3 | 0.3 | 0.7 |
Incentive Sensitization - Breakpoint | 0.3 | 0.3 | 0.6 | -0.5 | 0.5 | 0.4 | -0.4 | 0.4 | 0.6 | 0.7 | -0.6 | -0.6 | -0.3 | -0.8 | -0.5 | -0.4 | 0.7 | -0.6 | 0.7 | 0.4 | -0.4 | -0.6 | -0.5 | -0.3 | 0.5 | -0.5 | -0.6 | 0.6 | 0.3 |
Progressive ratio test 2 active lever presses | 0.3 | 0.4 | 0.7 | 0.6 | -0.6 | -0.6 | 0.7 | -0.7 | -0.6 | -0.5 | 0.5 | 0.5 | 0.6 | 0.7 | 0.4 | 0.3 | -0.8 | 0.5 | -0.8 | -0.5 | 0.5 | 0.5 | 0.6 | 0.6 | -0.7 | 0.7 | 0.5 | -0.5 | -0.6 |
Short access day 1 locomotion | 0.3 | 0.3 | 1.3 | -0.5 | 0.5 | 0.7 | -0.4 | 0.4 | 0.3 | 0.4 | -0.5 | -0.5 | -0.7 | -0.2 | -0.5 | 1.2 | 0.3 | -0.5 | 0.3 | 0.8 | -0.8 | -0.5 | -0.5 | -0.8 | 0.4 | -0.4 | -0.5 | 0.5 | 0.7 |
Locomotion velocity, session 2 | 0.3 | 0.3 | 0.4 | -0.6 | 0.6 | 0.6 | -0.6 | 0.5 | 0.6 | 0.6 | -0.6 | -0.6 | -0.5 | -0.6 | -0.6 | 0.3 | 0.6 | -0.6 | 0.6 | 0.6 | -0.6 | -0.6 | -0.6 | -0.6 | 0.6 | -0.6 | -0.6 | 0.6 | 0.6 |
Pavlov. Cond. lever latency | 0.3 | 0.3 | 0.4 | 0.6 | -0.6 | -0.6 | 0.6 | -0.5 | -0.5 | -0.5 | 0.6 | 0.6 | 0.6 | 0.6 | 0.5 | -0.4 | -0.6 | 0.6 | -0.6 | -0.5 | 0.5 | 0.5 | 0.6 | 0.5 | -0.6 | 0.6 | 0.6 | -0.6 | -0.6 |
Pavlov. Cond. change in total contacts | 0.3 | 0.4 | 0.5 | -0.6 | 0.6 | 0.7 | -0.6 | 0.5 | 0.5 | 0.5 | -0.6 | -0.6 | -0.7 | -0.6 | -0.6 | 0.7 | 0.6 | -0.6 | 0.6 | 0.7 | -0.7 | -0.6 | -0.6 | -0.7 | 0.5 | -0.5 | -0.6 | 0.6 | 0.7 |
Pavlov. Cond. response bias | 0.3 | 0.4 | 0.5 | 0.6 | -0.6 | -0.5 | 0.6 | -0.7 | -0.7 | -0.6 | 0.6 | 0.6 | 0.5 | 0.6 | 0.6 | -0.1 | -0.6 | 0.6 | -0.6 | -0.6 | 0.6 | 0.6 | 0.6 | 0.6 | -0.6 | 0.6 | 0.6 | -0.6 | -0.5 |
Bone: cortical thickness | 0.3 | 0.4 | 0.6 | 0.8 | -0.8 | -0.5 | 0.8 | -0.8 | -0.7 | -0.7 | 0.6 | 0.6 | 0.5 | 0.7 | 0.6 | 0.3 | -0.7 | 0.7 | -0.8 | -0.5 | 0.5 | 0.7 | 0.6 | 0.5 | -0.8 | 0.8 | 0.6 | -0.7 | -0.5 |
Delta time in closed arm before/after self-admin | 0.3 | 0.3 | 0.4 | -0.5 | 0.5 | 0.6 | -0.5 | 0.5 | 0.6 | 0.4 | -0.5 | -0.5 | -0.6 | -0.5 | -0.2 | -0.3 | 0.7 | -0.5 | 0.5 | 0.6 | -0.6 | -0.4 | -0.6 | -0.7 | 0.5 | -0.5 | -0.5 | 0.5 | 0.6 |
Delta ambulatory time before/after self-admin | 0.3 | 0.3 | 0.8 | -0.6 | 0.6 | 0.3 | -0.6 | 0.5 | 0.7 | 0.7 | -0.6 | -0.5 | -0.4 | -0.5 | -0.8 | 0.9 | 0.4 | -0.6 | 0.5 | 0.2 | -0.2 | -0.6 | -0.5 | -0.2 | 0.5 | -0.5 | -0.6 | 0.6 | 0.4 |
Delay disc. indifference point, 16s delay | 0.3 | 0.3 | 0.6 | -0.6 | 0.6 | 0.2 | -0.6 | 0.3 | 0.7 | 0.7 | -0.5 | -0.5 | -0.2 | -0.6 | -0.8 | -0.4 | 0.7 | -0.5 | 0.7 | 0.2 | -0.2 | -0.6 | -0.4 | -0.3 | 0.6 | -0.6 | -0.5 | 0.6 | 0.2 |
Progressive ratio | 0.3 | 0.3 | 0.8 | 0.5 | -0.5 | -0.7 | 0.5 | -0.6 | -0.4 | -0.4 | 0.5 | 0.5 | 0.8 | 0.3 | 0.5 | -0.9 | -0.5 | 0.5 | -0.5 | -0.6 | 0.6 | 0.5 | 0.6 | 0.5 | -0.5 | 0.5 | 0.5 | -0.5 | -0.8 |
Run reversals in cocaine runway, males | 0.3 | 0.3 | 0.7 | -0.5 | 0.5 | 0.6 | -0.5 | 0.5 | 0.8 | 0.6 | -0.6 | -0.6 | -0.6 | -0.4 | -0.7 | 0.8 | 0.4 | -0.6 | 0.5 | 0.5 | -0.5 | -0.6 | -0.5 | -0.5 | 0.5 | -0.5 | -0.6 | 0.6 | 0.6 |
Cu content in liver | 0.3 | 0.4 | 0.5 | 0.6 | -0.6 | -0.7 | 0.6 | -0.6 | -0.7 | -0.6 | 0.7 | 0.7 | 0.7 | 0.6 | 0.6 | -0.5 | -0.6 | 0.7 | -0.6 | -0.7 | 0.7 | 0.7 | 0.7 | 0.6 | -0.6 | 0.6 | 0.7 | -0.7 | -0.7 |
BMI without tail | 0.2 | 0.5 | 0.6 | -0.7 | 0.7 | 0.7 | -0.8 | 0.7 | 0.8 | 0.8 | -0.7 | -0.7 | -0.7 | -0.8 | -0.7 | 0.5 | 0.8 | -0.7 | 0.7 | 0.7 | -0.7 | -0.7 | -0.7 | -0.7 | 0.7 | -0.7 | -0.7 | 0.7 | 0.7 |
Glucose | 0.2 | 0.3 | 2.4 | -0.2 | 0.2 | 0.8 | -0.2 | 0.2 | 0.1 | 0.1 | -0.3 | -0.4 | -0.8 | -0.2 | -0.2 | 1.6 | 0.2 | -0.3 | 0.1 | 0.9 | -0.9 | -0.3 | -0.4 | -0.9 | 0.1 | -0.1 | -0.4 | 0.3 | 0.8 |
Delay discounting water rate 6 sec | 0.2 | 0.4 | 0.6 | -0.6 | 0.6 | 0.6 | -0.6 | 0.6 | 0.7 | 0.6 | -0.6 | -0.6 | -0.6 | -0.8 | -0.6 | -0.3 | 0.6 | -0.6 | 0.5 | 0.5 | -0.5 | -0.6 | -0.6 | -0.5 | 0.6 | -0.6 | -0.6 | 0.6 | 0.6 |
Light reinforcement 2 | 0.2 | 0.3 | 0.4 | 0.4 | -0.4 | -0.5 | 0.4 | -0.6 | -0.5 | -0.6 | 0.6 | 0.6 | 0.4 | 0.7 | 0.7 | -0.1 | -0.5 | 0.5 | -0.4 | -0.5 | 0.5 | 0.6 | 0.5 | 0.6 | -0.5 | 0.5 | 0.5 | -0.5 | -0.4 |
Reaction time mean minus median | 0.2 | 0.3 | 0.7 | -0.6 | 0.6 | 0.1 | -0.6 | 0.5 | 0.6 | 0.6 | -0.5 | -0.4 | -0.1 | -0.6 | -0.5 | -0.8 | 0.6 | -0.5 | 0.7 | 0.2 | -0.2 | -0.5 | -0.4 | -0.2 | 0.5 | -0.5 | -0.5 | 0.5 | 0.1 |
Reaction time num false alarms | 0.2 | 0.3 | 1.0 | -0.5 | 0.5 | 0.5 | -0.5 | 0.6 | 0.5 | 0.5 | -0.5 | -0.5 | -0.4 | -0.4 | -0.7 | 1.0 | 0.5 | -0.5 | 0.4 | 0.6 | -0.6 | -0.6 | -0.5 | -0.5 | 0.5 | -0.5 | -0.5 | 0.5 | 0.4 |
Saline control response | 0.2 | 0.2 | 1.5 | 0.6 | -0.6 | 0.1 | 0.6 | -0.5 | -0.5 | -0.5 | 0.4 | 0.3 | -0.1 | 0.5 | 0.4 | 1.2 | -0.5 | 0.4 | -0.5 | 0.1 | -0.1 | 0.4 | 0.3 | -0.1 | -0.5 | 0.5 | 0.3 | -0.4 | 0.1 |
Intermittent access day 1 total infusions | 0.2 | 0.2 | 0.9 | 0.4 | -0.4 | -0.2 | 0.5 | -0.5 | -0.7 | -0.5 | 0.4 | 0.4 | 0.2 | 0.7 | 0.2 | 0.9 | -0.7 | 0.5 | -0.6 | -0.2 | 0.2 | 0.4 | 0.5 | 0.2 | -0.5 | 0.5 | 0.4 | -0.5 | -0.2 |
Intermittent access terminal intake (last 3 days) | 0.2 | 0.2 | 0.4 | 0.4 | -0.4 | -0.6 | 0.5 | -0.5 | -0.5 | -0.3 | 0.4 | 0.4 | 0.6 | 0.5 | 0.2 | -0.1 | -0.6 | 0.4 | -0.6 | -0.4 | 0.4 | 0.4 | 0.5 | 0.5 | -0.5 | 0.5 | 0.4 | -0.4 | -0.6 |
Intermittent access total locomotion | 0.2 | 0.2 | 1.1 | -0.5 | 0.5 | 0.5 | -0.4 | 0.5 | 0.3 | 0.3 | -0.4 | -0.4 | -0.5 | -0.3 | -0.6 | 1.1 | 0.1 | -0.4 | 0.1 | 0.5 | -0.5 | -0.4 | -0.4 | -0.6 | 0.3 | -0.3 | -0.4 | 0.4 | 0.5 |
Incentive Sensitization - Responses | 0.2 | 0.2 | 0.4 | -0.4 | 0.4 | 0.3 | -0.4 | 0.3 | 0.4 | 0.6 | -0.5 | -0.5 | -0.3 | -0.6 | -0.4 | -0.4 | 0.6 | -0.5 | 0.6 | 0.4 | -0.4 | -0.5 | -0.5 | -0.3 | 0.4 | -0.4 | -0.5 | 0.5 | 0.3 |
Short access total locomotion | 0.2 | 0.2 | 0.9 | 0.3 | -0.3 | -0.2 | 0.3 | -0.3 | -0.5 | -0.5 | 0.4 | 0.4 | 0.2 | 0.5 | 0.2 | 0.9 | -0.5 | 0.4 | -0.5 | -0.2 | 0.2 | 0.4 | 0.4 | 0.1 | -0.4 | 0.4 | 0.4 | -0.4 | -0.2 |
Locomotion distance, session 7 | 0.2 | 0.3 | 0.4 | 0.6 | -0.6 | -0.5 | 0.6 | -0.6 | -0.6 | -0.6 | 0.6 | 0.6 | 0.4 | 0.6 | 0.6 | -0.1 | -0.6 | 0.6 | -0.6 | -0.5 | 0.5 | 0.6 | 0.6 | 0.5 | -0.6 | 0.6 | 0.6 | -0.6 | -0.4 |
Condit. Reinf. active responses | 0.2 | 0.2 | 0.4 | -0.4 | 0.4 | 0.4 | -0.4 | 0.3 | 0.6 | 0.5 | -0.5 | -0.5 | -0.4 | -0.4 | -0.6 | 0.4 | 0.4 | -0.5 | 0.4 | 0.4 | -0.4 | -0.5 | -0.4 | -0.4 | 0.4 | -0.4 | -0.5 | 0.5 | 0.4 |
Condit. Reinf. inactive responses | 0.2 | 0.3 | 1.4 | -0.4 | 0.4 | 0.6 | -0.4 | 0.3 | 0.6 | 0.5 | -0.5 | -0.5 | -0.7 | -0.3 | -0.6 | 1.2 | 0.4 | -0.5 | 0.4 | 0.5 | -0.5 | -0.5 | -0.5 | -0.5 | 0.4 | -0.4 | -0.5 | 0.5 | 0.7 |
Condit. Reinf. lever presses | 0.2 | 0.3 | 0.5 | 0.5 | -0.5 | -0.4 | 0.5 | -0.7 | -0.5 | -0.5 | 0.5 | 0.5 | 0.4 | 0.6 | 0.4 | 0.2 | -0.6 | 0.5 | -0.6 | -0.5 | 0.5 | 0.5 | 0.5 | 0.5 | -0.6 | 0.6 | 0.5 | -0.5 | -0.4 |
Locomotion velocity, hab. session 1 | 0.2 | 0.3 | 0.8 | 0.4 | -0.4 | -0.7 | 0.4 | -0.4 | -0.3 | -0.3 | 0.4 | 0.5 | 0.7 | 0.4 | 0.3 | -0.9 | -0.4 | 0.4 | -0.4 | -0.7 | 0.7 | 0.4 | 0.5 | 0.7 | -0.4 | 0.4 | 0.4 | -0.4 | -0.7 |
Total locomotion distance, NPP test | 0.2 | 0.3 | 0.5 | 0.4 | -0.4 | -0.7 | 0.4 | -0.5 | -0.3 | -0.3 | 0.4 | 0.5 | 0.7 | 0.4 | 0.3 | -0.7 | -0.4 | 0.4 | -0.4 | -0.7 | 0.7 | 0.4 | 0.5 | 0.7 | -0.4 | 0.4 | 0.4 | -0.4 | -0.7 |
Bone: stiffness | 0.2 | 0.2 | 0.4 | 0.6 | -0.6 | -0.5 | 0.6 | -0.5 | -0.4 | -0.4 | 0.4 | 0.5 | 0.5 | 0.4 | 0.3 | -0.1 | -0.5 | 0.4 | -0.5 | -0.6 | 0.6 | 0.4 | 0.5 | 0.6 | -0.5 | 0.5 | 0.5 | -0.4 | -0.5 |
Distance traveled after self-admin | 0.2 | 0.2 | 0.8 | -0.1 | 0.1 | -0.3 | -0.3 | -0.2 | 0.9 | 0.6 | -0.3 | -0.2 | 0.2 | -0.5 | -0.8 | 0.2 | 0.4 | -0.3 | 0.4 | -0.7 | 0.7 | -0.4 | -0.0 | 0.4 | 0.1 | -0.1 | -0.3 | 0.3 | -0.2 |
Time in closed arm after self-admin | 0.2 | 0.2 | 0.6 | -0.7 | 0.7 | 0.4 | -0.6 | 0.6 | 0.3 | 0.1 | -0.2 | -0.2 | -0.4 | -0.2 | 0.2 | -0.8 | 0.6 | -0.2 | 0.6 | 0.3 | -0.3 | -0.1 | -0.4 | -0.4 | 0.5 | -0.5 | -0.2 | 0.2 | 0.4 |
Time to tail flick, test, before self-admin | 0.2 | 0.2 | 0.4 | -0.3 | 0.3 | 0.5 | -0.3 | 0.3 | 0.3 | 0.4 | -0.4 | -0.5 | -0.5 | -0.6 | -0.6 | 0.1 | 0.5 | -0.4 | 0.4 | 0.5 | -0.5 | -0.4 | -0.5 | -0.5 | 0.4 | -0.4 | -0.5 | 0.4 | 0.5 |
Delta time to tail flick, vehicle, before/after SA | 0.2 | 0.2 | 2.1 | 0.0 | -0.0 | -0.3 | 0.1 | -0.2 | -0.4 | -0.4 | 0.4 | 0.4 | 0.3 | -0.0 | 0.5 | -1.4 | -0.0 | 0.4 | 0.0 | -0.4 | 0.4 | 0.4 | 0.3 | 0.5 | -0.1 | 0.1 | 0.4 | -0.4 | -0.3 |
Delta time to tail flick, test, before/after SA | 0.2 | 0.2 | 0.3 | -0.6 | 0.6 | 0.3 | -0.5 | 0.5 | 0.3 | 0.4 | -0.4 | -0.3 | -0.4 | -0.3 | -0.4 | 0.2 | 0.5 | -0.4 | 0.5 | 0.2 | -0.2 | -0.4 | -0.4 | -0.2 | 0.5 | -0.5 | -0.4 | 0.4 | 0.4 |
Delay disc. indifference point, 24s delay | 0.2 | 0.2 | 0.3 | 0.4 | -0.4 | -0.6 | 0.4 | -0.5 | -0.4 | -0.4 | 0.5 | 0.5 | 0.6 | 0.5 | 0.4 | -0.1 | -0.5 | 0.5 | -0.5 | -0.6 | 0.6 | 0.5 | 0.5 | 0.5 | -0.5 | 0.5 | 0.5 | -0.5 | -0.6 |
Change in fecal boli incidents, locomotor task | 0.2 | 0.2 | 0.2 | 0.5 | -0.5 | -0.4 | 0.5 | -0.3 | -0.2 | -0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.5 | -0.2 | -0.5 | 0.4 | -0.5 | -0.4 | 0.4 | 0.4 | 0.4 | 0.4 | -0.4 | 0.4 | 0.4 | -0.4 | -0.4 |
Vertical activity count, locomotor time 1 | 0.2 | 0.2 | 0.4 | -0.6 | 0.6 | 0.4 | -0.6 | 0.4 | 0.4 | 0.5 | -0.4 | -0.4 | -0.5 | -0.6 | -0.3 | 0.2 | 0.5 | -0.4 | 0.6 | 0.2 | -0.2 | -0.4 | -0.5 | -0.2 | 0.5 | -0.5 | -0.4 | 0.4 | 0.5 |
Vertical activity count, locomotor time 2 | 0.2 | 0.3 | 0.5 | 0.4 | -0.4 | -0.5 | 0.4 | -0.5 | -0.7 | -0.5 | 0.5 | 0.5 | 0.4 | 0.4 | 0.6 | -0.2 | -0.4 | 0.5 | -0.4 | -0.6 | 0.6 | 0.6 | 0.5 | 0.6 | -0.5 | 0.5 | 0.5 | -0.5 | -0.4 |
Latency to leave start box in cocaine runway | 0.2 | 0.3 | 0.4 | 0.6 | -0.6 | -0.3 | 0.6 | -0.6 | -0.5 | -0.5 | 0.5 | 0.5 | 0.3 | 0.4 | 0.5 | 0.4 | -0.6 | 0.5 | -0.6 | -0.4 | 0.4 | 0.5 | 0.5 | 0.5 | -0.6 | 0.6 | 0.5 | -0.5 | -0.3 |
Latency to leave start box in cocaine runway, M | 0.2 | 0.2 | 0.3 | 0.5 | -0.5 | -0.3 | 0.5 | -0.5 | -0.4 | -0.5 | 0.5 | 0.5 | 0.3 | 0.5 | 0.4 | 0.4 | -0.5 | 0.5 | -0.5 | -0.4 | 0.4 | 0.5 | 0.5 | 0.5 | -0.5 | 0.5 | 0.5 | -0.5 | -0.3 |
BMI with tail | 0.1 | 0.3 | 0.4 | -0.7 | 0.7 | 0.5 | -0.6 | 0.6 | 0.3 | 0.5 | -0.5 | -0.5 | -0.5 | -0.6 | -0.5 | -0.0 | 0.6 | -0.5 | 0.7 | 0.5 | -0.5 | -0.5 | -0.6 | -0.6 | 0.6 | -0.6 | -0.5 | 0.5 | 0.5 |
Body weight | 0.1 | 0.4 | 0.5 | 0.7 | -0.7 | -0.7 | 0.7 | -0.6 | -0.5 | -0.5 | 0.5 | 0.6 | 0.6 | 0.6 | 0.5 | -0.1 | -0.7 | 0.5 | -0.7 | -0.6 | 0.6 | 0.5 | 0.6 | 0.7 | -0.7 | 0.7 | 0.5 | -0.5 | -0.6 |
Length without tail | 0.1 | 0.2 | 0.4 | 0.6 | -0.6 | -0.4 | 0.6 | -0.4 | -0.4 | -0.3 | 0.4 | 0.4 | 0.4 | 0.4 | 0.3 | 0.2 | -0.6 | 0.4 | -0.6 | -0.3 | 0.3 | 0.4 | 0.4 | 0.4 | -0.5 | 0.5 | 0.4 | -0.4 | -0.4 |
Intraocular pressure | 0.1 | 0.1 | 0.5 | -0.2 | 0.2 | 0.5 | -0.2 | 0.1 | -0.1 | 0.0 | -0.1 | -0.2 | -0.5 | -0.1 | -0.0 | 0.7 | 0.2 | -0.1 | 0.2 | 0.4 | -0.4 | -0.1 | -0.2 | -0.4 | 0.2 | -0.2 | -0.1 | 0.1 | 0.5 |
Soleus weight | 0.1 | 0.3 | 1.0 | 0.5 | -0.5 | -0.8 | 0.5 | -0.5 | -0.5 | -0.4 | 0.5 | 0.5 | 0.8 | 0.5 | 0.5 | -1.0 | -0.5 | 0.5 | -0.5 | -0.6 | 0.6 | 0.5 | 0.6 | 0.7 | -0.5 | 0.5 | 0.5 | -0.5 | -0.8 |
Mean num. licks in bursts | 0.1 | 0.1 | 0.8 | -0.0 | 0.0 | 0.4 | -0.0 | 0.2 | -0.2 | -0.1 | -0.1 | -0.1 | -0.4 | 0.0 | 0.1 | 0.9 | -0.0 | -0.1 | 0.0 | 0.4 | -0.4 | -0.0 | -0.2 | -0.4 | 0.0 | -0.0 | -0.1 | 0.1 | 0.4 |
Water consumed over 24 hours | 0.1 | 0.1 | 0.2 | -0.4 | 0.4 | 0.1 | -0.4 | 0.5 | 0.4 | 0.4 | -0.3 | -0.3 | -0.1 | -0.3 | -0.5 | -0.1 | 0.4 | -0.4 | 0.4 | 0.2 | -0.2 | -0.4 | -0.3 | -0.2 | 0.4 | -0.4 | -0.3 | 0.4 | 0.1 |
Indifference point function ln k | 0.1 | 0.1 | 0.2 | 0.3 | -0.3 | -0.3 | 0.3 | -0.3 | -0.4 | -0.4 | 0.4 | 0.4 | 0.3 | 0.4 | 0.5 | -0.4 | -0.3 | 0.4 | -0.4 | -0.3 | 0.3 | 0.4 | 0.4 | 0.3 | -0.3 | 0.3 | 0.4 | -0.4 | -0.3 |
Indifference point function log k | 0.1 | 0.1 | 0.2 | 0.3 | -0.3 | -0.3 | 0.3 | -0.3 | -0.4 | -0.4 | 0.4 | 0.4 | 0.3 | 0.4 | 0.5 | -0.4 | -0.3 | 0.4 | -0.4 | -0.3 | 0.3 | 0.4 | 0.4 | 0.3 | -0.3 | 0.3 | 0.4 | -0.4 | -0.3 |
Delay discounting water rate 18 sec | 0.1 | 0.2 | 0.4 | -0.3 | 0.3 | 0.4 | -0.4 | 0.3 | 0.6 | 0.4 | -0.4 | -0.5 | -0.4 | -0.5 | -0.4 | 0.2 | 0.3 | -0.4 | 0.4 | 0.4 | -0.4 | -0.5 | -0.4 | -0.4 | 0.4 | -0.4 | -0.4 | 0.4 | 0.4 |
Reaction time mean minus median AUC | 0.1 | 0.1 | 1.2 | -0.2 | 0.2 | -0.3 | -0.2 | 0.1 | 0.2 | 0.2 | -0.1 | -0.0 | 0.3 | -0.2 | -0.1 | -1.1 | 0.2 | -0.1 | 0.3 | -0.2 | 0.2 | -0.1 | 0.0 | 0.2 | 0.1 | -0.1 | -0.1 | 0.1 | -0.3 |
Social time | 0.1 | 0.2 | 0.8 | 0.0 | -0.0 | 0.7 | -0.0 | 0.0 | -0.1 | -0.1 | -0.1 | -0.2 | -0.6 | -0.1 | 0.3 | 0.7 | 0.2 | -0.1 | 0.2 | 0.9 | -0.9 | -0.0 | -0.3 | -0.8 | 0.1 | -0.1 | -0.1 | 0.1 | 0.6 |
Cocaine induced anxiety | 0.1 | 0.1 | 0.3 | -0.0 | 0.0 | 0.0 | 0.1 | -0.0 | -0.5 | -0.4 | 0.3 | 0.2 | -0.1 | 0.6 | 0.3 | 0.6 | -0.2 | 0.2 | -0.3 | -0.1 | 0.1 | 0.2 | 0.1 | -0.1 | -0.1 | 0.1 | 0.2 | -0.3 | 0.1 |
Lifetime Intake | 0.1 | 0.1 | 0.4 | 0.3 | -0.3 | -0.2 | 0.4 | -0.3 | -0.5 | -0.4 | 0.4 | 0.3 | 0.2 | 0.6 | 0.2 | 0.6 | -0.6 | 0.4 | -0.5 | -0.1 | 0.1 | 0.3 | 0.4 | 0.2 | -0.4 | 0.4 | 0.3 | -0.4 | -0.2 |
Short access day 1 total inactive lever presses | 0.1 | 0.1 | 1.3 | -0.2 | 0.2 | 0.4 | -0.2 | 0.1 | 0.1 | 0.3 | -0.3 | -0.3 | -0.4 | -0.3 | -0.4 | 1.2 | -0.1 | -0.3 | 0.0 | 0.5 | -0.5 | -0.3 | -0.3 | -0.5 | 0.1 | -0.1 | -0.3 | 0.3 | 0.4 |
Short access total infusions | 0.1 | 0.1 | 1.6 | 0.2 | -0.2 | 0.1 | 0.2 | -0.1 | -0.2 | -0.2 | 0.1 | 0.1 | -0.0 | 0.4 | -0.1 | 1.3 | -0.4 | 0.1 | -0.4 | 0.1 | -0.1 | 0.1 | 0.2 | -0.1 | -0.3 | 0.3 | 0.1 | -0.1 | 0.0 |
One hour access (0.3 mA shock) | 0.1 | 0.1 | 0.5 | 0.2 | -0.2 | -0.2 | 0.3 | -0.1 | -0.1 | -0.1 | 0.1 | 0.1 | 0.3 | 0.4 | -0.3 | 0.7 | -0.4 | 0.1 | -0.3 | -0.1 | 0.1 | 0.1 | 0.3 | 0.2 | -0.2 | 0.2 | 0.1 | -0.1 | -0.3 |
Locomotion velocity, session 1 | 0.1 | 0.1 | 0.1 | -0.4 | 0.4 | 0.1 | -0.3 | 0.2 | 0.3 | 0.3 | -0.3 | -0.3 | -0.1 | -0.3 | -0.3 | -0.3 | 0.3 | -0.3 | 0.3 | 0.2 | -0.2 | -0.3 | -0.3 | -0.2 | 0.3 | -0.3 | -0.3 | 0.3 | 0.1 |
Locomotion distance, session 2 | 0.1 | 0.1 | 0.2 | -0.3 | 0.3 | 0.1 | -0.3 | 0.2 | 0.4 | 0.4 | -0.3 | -0.3 | -0.1 | -0.4 | -0.5 | -0.1 | 0.3 | -0.3 | 0.3 | 0.1 | -0.1 | -0.4 | -0.2 | -0.1 | 0.3 | -0.3 | -0.3 | 0.3 | 0.1 |
Degree of sensitization distance | 0.1 | 0.1 | 0.1 | -0.2 | 0.2 | 0.2 | -0.2 | 0.3 | 0.3 | 0.3 | -0.3 | -0.3 | -0.2 | -0.2 | -0.3 | -0.0 | 0.3 | -0.3 | 0.3 | 0.3 | -0.3 | -0.3 | -0.3 | -0.3 | 0.3 | -0.3 | -0.3 | 0.3 | 0.2 |
Condit. Reinf. active-inactive response ratio | 0.1 | 0.1 | 0.2 | 0.3 | -0.3 | -0.3 | 0.3 | -0.4 | -0.4 | -0.4 | 0.3 | 0.3 | 0.3 | 0.3 | 0.4 | -0.3 | -0.3 | 0.3 | -0.3 | -0.2 | 0.2 | 0.3 | 0.3 | 0.2 | -0.3 | 0.3 | 0.3 | -0.3 | -0.3 |
Total locomotion distance, hab. session 1 | 0.1 | 0.2 | 0.8 | 0.3 | -0.3 | -0.6 | 0.3 | -0.3 | -0.2 | -0.2 | 0.3 | 0.4 | 0.6 | 0.3 | 0.2 | -0.9 | -0.3 | 0.3 | -0.3 | -0.7 | 0.7 | 0.3 | 0.4 | 0.7 | -0.3 | 0.3 | 0.4 | -0.3 | -0.6 |
Bone: apparent density | 0.1 | 0.2 | 0.3 | 0.5 | -0.5 | -0.4 | 0.5 | -0.5 | -0.5 | -0.5 | 0.5 | 0.5 | 0.3 | 0.6 | 0.5 | 0.2 | -0.5 | 0.5 | -0.5 | -0.4 | 0.4 | 0.5 | 0.5 | 0.4 | -0.5 | 0.5 | 0.5 | -0.5 | -0.3 |
Bone: cortical area | 0.1 | 0.2 | 0.9 | -0.2 | 0.2 | 0.5 | -0.2 | 0.2 | 0.4 | 0.4 | -0.4 | -0.4 | -0.5 | -0.3 | -0.5 | 0.9 | 0.3 | -0.4 | 0.3 | 0.5 | -0.5 | -0.4 | -0.4 | -0.5 | 0.3 | -0.3 | -0.4 | 0.4 | 0.5 |
Bone: maximum force | 0.1 | 0.2 | 0.3 | 0.6 | -0.6 | -0.4 | 0.6 | -0.5 | -0.4 | -0.4 | 0.4 | 0.4 | 0.3 | 0.4 | 0.4 | 0.3 | -0.4 | 0.4 | -0.5 | -0.5 | 0.5 | 0.4 | 0.4 | 0.5 | -0.5 | 0.5 | 0.4 | -0.4 | -0.4 |
Bone: maximum moment | 0.1 | 0.1 | 0.7 | -0.1 | 0.1 | 0.4 | -0.1 | 0.2 | 0.3 | 0.3 | -0.3 | -0.3 | -0.4 | -0.3 | -0.3 | 0.8 | 0.2 | -0.3 | 0.2 | 0.3 | -0.3 | -0.3 | -0.3 | -0.3 | 0.2 | -0.2 | -0.3 | 0.3 | 0.4 |
Distance traveled before self-admin | 0.1 | 0.1 | 0.7 | 0.3 | -0.3 | -0.4 | 0.2 | -0.7 | 0.2 | -0.0 | 0.2 | 0.3 | 0.3 | 0.0 | 0.0 | -0.1 | 0.1 | 0.2 | 0.1 | -0.8 | 0.8 | 0.1 | 0.3 | 0.6 | -0.3 | 0.3 | 0.2 | -0.2 | -0.3 |
Active lever presses in extinction session 6 | 0.1 | 0.1 | 0.3 | 0.3 | -0.3 | -0.3 | 0.2 | -0.5 | -0.5 | -0.2 | 0.3 | 0.3 | 0.3 | 0.3 | 0.1 | 0.6 | -0.2 | 0.3 | -0.3 | -0.6 | 0.6 | 0.3 | 0.3 | 0.4 | -0.4 | 0.4 | 0.3 | -0.3 | -0.3 |
Time in closed arm before self-admin | 0.1 | 0.1 | 0.1 | -0.0 | 0.0 | -0.3 | 0.1 | -0.1 | -0.3 | -0.3 | 0.3 | 0.3 | 0.2 | 0.4 | 0.2 | 0.3 | -0.2 | 0.3 | -0.1 | -0.3 | 0.3 | 0.3 | 0.3 | 0.4 | -0.2 | 0.2 | 0.3 | -0.3 | -0.2 |
Time in open arm before self-admin | 0.1 | 0.1 | 0.4 | 0.3 | -0.3 | -0.2 | 0.2 | -0.2 | 0.6 | 0.4 | -0.3 | -0.2 | 0.2 | -0.1 | -0.4 | 0.3 | 0.0 | -0.2 | -0.1 | -0.1 | 0.1 | -0.3 | -0.0 | 0.1 | -0.1 | 0.1 | -0.2 | 0.2 | -0.2 |
Ambulatory time after self-admin | 0.1 | 0.1 | 0.6 | -0.2 | 0.2 | -0.1 | -0.3 | -0.1 | 0.8 | 0.5 | -0.3 | -0.2 | 0.0 | -0.5 | -0.6 | 0.5 | 0.2 | -0.3 | 0.4 | -0.5 | 0.5 | -0.4 | -0.1 | 0.3 | 0.1 | -0.1 | -0.3 | 0.3 | -0.0 |
Time >=10cm from walls, locomotor time 1 | 0.1 | 0.1 | 0.2 | -0.3 | 0.3 | 0.3 | -0.3 | 0.4 | 0.2 | 0.3 | -0.3 | -0.3 | -0.3 | -0.3 | -0.4 | 0.2 | 0.3 | -0.3 | 0.3 | 0.4 | -0.4 | -0.3 | -0.3 | -0.4 | 0.3 | -0.3 | -0.3 | 0.3 | 0.3 |
Bouts of movement, locomotor time 1 | 0.1 | 0.1 | 1.4 | -0.1 | 0.1 | 0.4 | -0.1 | 0.4 | 0.1 | 0.2 | -0.2 | -0.2 | -0.4 | -0.0 | -0.4 | 1.2 | 0.1 | -0.2 | 0.1 | 0.2 | -0.2 | -0.2 | -0.2 | -0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.4 |
Total resting periods, locomotor time 1 | 0.1 | 0.1 | 1.4 | -0.1 | 0.1 | 0.3 | -0.1 | 0.4 | 0.2 | 0.2 | -0.2 | -0.2 | -0.4 | -0.0 | -0.4 | 1.2 | 0.0 | -0.2 | 0.1 | 0.2 | -0.2 | -0.2 | -0.3 | -0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.4 |
Distance moved, locomotor task time 1 | 0.1 | 0.1 | 0.8 | -0.1 | 0.1 | -0.0 | -0.1 | -0.2 | -0.4 | -0.3 | 0.2 | 0.2 | 0.0 | -0.1 | 0.7 | -0.9 | 0.0 | 0.2 | 0.0 | -0.1 | 0.1 | 0.3 | 0.0 | 0.1 | -0.0 | 0.0 | 0.2 | -0.2 | -0.0 |
Seeking ratio, delayed vs. immediate footshock | 0.1 | 0.1 | 0.2 | 0.3 | -0.3 | -0.4 | 0.3 | -0.2 | 0.3 | -0.1 | 0.2 | 0.2 | 0.5 | 0.3 | -0.2 | 0.3 | -0.3 | 0.2 | -0.4 | -0.3 | 0.3 | 0.1 | 0.3 | 0.1 | -0.3 | 0.3 | 0.2 | -0.2 | -0.5 |
Latency to leave start box in cocaine runway, F | 0.1 | 0.1 | 0.1 | 0.3 | -0.3 | -0.1 | 0.3 | -0.3 | -0.2 | -0.2 | 0.2 | 0.2 | 0.0 | 0.1 | 0.2 | 0.3 | -0.3 | 0.2 | -0.3 | -0.2 | 0.2 | 0.2 | 0.2 | 0.2 | -0.3 | 0.3 | 0.2 | -0.2 | -0.0 |
Co content in liver | 0.1 | 0.1 | 0.2 | 0.4 | -0.4 | -0.3 | 0.4 | -0.4 | -0.4 | -0.3 | 0.3 | 0.3 | 0.2 | 0.4 | 0.3 | 0.3 | -0.4 | 0.3 | -0.4 | -0.4 | 0.4 | 0.3 | 0.3 | 0.4 | -0.4 | 0.4 | 0.3 | -0.3 | -0.2 |
Mn content in liver | 0.1 | 0.1 | 0.1 | 0.2 | -0.2 | -0.4 | 0.2 | -0.2 | -0.2 | -0.2 | 0.2 | 0.2 | 0.3 | 0.3 | 0.1 | -0.3 | -0.2 | 0.2 | -0.2 | -0.3 | 0.3 | 0.2 | 0.3 | 0.4 | -0.2 | 0.2 | 0.2 | -0.2 | -0.3 |
Sr content in liver | 0.1 | 0.1 | 0.1 | -0.2 | 0.2 | 0.2 | -0.2 | 0.1 | 0.2 | 0.2 | -0.2 | -0.2 | -0.2 | -0.2 | -0.2 | 0.3 | 0.2 | -0.2 | 0.2 | 0.2 | -0.2 | -0.2 | -0.2 | -0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 |
Number of licking bursts | 0.0 | 0.1 | 0.5 | -0.2 | 0.2 | -0.2 | -0.2 | 0.1 | 0.3 | 0.2 | -0.1 | -0.1 | 0.2 | -0.2 | -0.3 | -0.7 | 0.2 | -0.1 | 0.2 | -0.2 | 0.2 | -0.2 | -0.0 | 0.2 | 0.2 | -0.2 | -0.1 | 0.1 | -0.2 |
Times rat made contact with spout | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | 0.0 | -0.1 | 0.3 | -0.0 | 0.1 | -0.1 | -0.1 | 0.0 | -0.0 | -0.1 | 0.0 | 0.1 | -0.1 | 0.1 | 0.2 | -0.2 | -0.1 | -0.1 | -0.2 | 0.1 | -0.1 | -0.1 | 0.1 | -0.0 |
Std. dev. time between licks in bursts | 0.0 | 0.0 | 0.1 | -0.0 | 0.0 | -0.0 | -0.0 | -0.1 | -0.0 | 0.1 | -0.0 | 0.0 | -0.0 | -0.1 | -0.0 | -0.3 | 0.1 | -0.0 | 0.0 | -0.1 | 0.1 | -0.0 | -0.0 | 0.1 | 0.0 | -0.0 | -0.0 | 0.0 | 0.0 |
Delay discounting water rate 24 sec | 0.0 | 0.0 | 0.2 | 0.1 | -0.1 | -0.1 | 0.1 | -0.0 | 0.3 | 0.1 | -0.1 | -0.0 | 0.2 | -0.1 | -0.2 | -0.5 | -0.1 | -0.1 | -0.0 | -0.1 | 0.1 | -0.1 | -0.0 | 0.1 | -0.0 | 0.0 | -0.1 | 0.1 | -0.2 |
Locomotor activity | 0.0 | 0.0 | 0.3 | 0.3 | -0.3 | 0.2 | 0.3 | -0.1 | 0.0 | -0.1 | 0.0 | -0.0 | -0.2 | 0.0 | 0.2 | 0.5 | -0.1 | 0.0 | -0.2 | 0.2 | -0.2 | 0.1 | -0.0 | -0.1 | -0.1 | 0.1 | 0.0 | -0.0 | 0.2 |
Locomotor testing rearing | 0.0 | 0.1 | 0.2 | 0.4 | -0.4 | -0.2 | 0.4 | -0.2 | -0.1 | -0.2 | 0.2 | 0.2 | 0.3 | 0.1 | 0.1 | -0.3 | -0.1 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 | 0.2 | 0.2 | -0.2 | 0.2 | 0.2 | -0.2 | -0.3 |
Reaction time number correct | 0.0 | 0.1 | 0.7 | 0.3 | -0.3 | -0.1 | 0.3 | -0.2 | 0.3 | 0.1 | -0.1 | -0.0 | 0.1 | 0.1 | -0.3 | 0.8 | -0.3 | -0.0 | -0.4 | -0.0 | 0.0 | -0.1 | 0.0 | 0.1 | -0.2 | 0.2 | -0.1 | 0.1 | -0.1 |
Reaction time trials correct on left | 0.0 | 0.1 | 0.7 | 0.3 | -0.3 | -0.1 | 0.3 | -0.2 | 0.3 | 0.1 | -0.1 | -0.0 | 0.1 | 0.1 | -0.3 | 0.8 | -0.3 | -0.0 | -0.4 | -0.0 | 0.0 | -0.1 | 0.0 | 0.1 | -0.2 | 0.2 | -0.1 | 0.1 | -0.1 |
Reaction time trials on left | 0.0 | 0.1 | 0.8 | 0.2 | -0.2 | -0.0 | 0.2 | -0.2 | 0.3 | 0.2 | -0.1 | -0.1 | 0.0 | 0.0 | -0.3 | 0.9 | -0.2 | -0.1 | -0.3 | 0.0 | -0.0 | -0.1 | -0.0 | -0.0 | -0.1 | 0.1 | -0.1 | 0.1 | -0.0 |
Reaction time trials completed | 0.0 | 0.1 | 0.8 | 0.2 | -0.2 | -0.0 | 0.2 | -0.2 | 0.3 | 0.2 | -0.1 | -0.1 | 0.0 | 0.0 | -0.3 | 0.9 | -0.2 | -0.1 | -0.3 | 0.0 | -0.0 | -0.1 | -0.0 | -0.0 | -0.1 | 0.1 | -0.1 | 0.1 | -0.0 |
Reaction time trials AUC | 0.0 | 0.1 | 0.7 | 0.2 | -0.2 | -0.0 | 0.2 | -0.2 | 0.3 | 0.2 | -0.1 | -0.1 | 0.0 | 0.0 | -0.3 | 0.8 | -0.2 | -0.1 | -0.3 | 0.1 | -0.1 | -0.2 | -0.0 | -0.0 | -0.1 | 0.1 | -0.1 | 0.1 | -0.0 |
Conditioned locomotion | 0.0 | 0.0 | 0.1 | 0.2 | -0.2 | -0.1 | 0.2 | -0.2 | -0.2 | -0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.1 | 0.0 | -0.2 | 0.2 | -0.2 | -0.1 | 0.1 | 0.2 | 0.2 | 0.1 | -0.2 | 0.2 | 0.2 | -0.2 | -0.2 |
Cocaine response before conditioning | 0.0 | 0.0 | 0.2 | -0.1 | 0.1 | -0.2 | -0.1 | 0.0 | -0.0 | -0.0 | 0.0 | 0.0 | 0.2 | 0.1 | 0.1 | -0.5 | 0.0 | 0.0 | 0.0 | -0.1 | 0.1 | 0.0 | 0.0 | 0.1 | 0.0 | -0.0 | 0.0 | -0.0 | -0.2 |
Intermittent access day 15 total locomotion | 0.0 | 0.0 | 0.3 | -0.2 | 0.2 | 0.1 | -0.2 | 0.2 | -0.2 | 0.1 | -0.1 | -0.1 | -0.1 | 0.0 | -0.3 | 0.5 | -0.1 | -0.1 | -0.1 | 0.2 | -0.2 | -0.1 | -0.1 | -0.3 | 0.1 | -0.1 | -0.1 | 0.1 | 0.1 |
Short access day 1 total infusions | 0.0 | 0.0 | 0.2 | -0.1 | 0.1 | 0.2 | -0.1 | 0.1 | 0.1 | 0.1 | -0.1 | -0.1 | -0.1 | 0.1 | -0.1 | 0.4 | -0.1 | -0.1 | -0.2 | 0.3 | -0.3 | -0.1 | -0.1 | -0.3 | -0.0 | 0.0 | -0.1 | 0.1 | 0.1 |
Locomotion velocity, session 3 | 0.0 | 0.0 | 0.2 | -0.0 | 0.0 | -0.1 | -0.0 | -0.0 | -0.0 | -0.0 | 0.0 | 0.0 | 0.1 | -0.1 | 0.0 | -0.4 | 0.0 | 0.0 | 0.0 | -0.1 | 0.1 | 0.0 | 0.0 | 0.1 | 0.0 | -0.0 | 0.0 | -0.0 | -0.1 |
Locomotion distance, session 3 | 0.0 | 0.0 | 0.1 | 0.0 | -0.0 | 0.1 | 0.0 | -0.1 | -0.0 | -0.0 | 0.0 | 0.0 | -0.1 | -0.0 | 0.0 | 0.3 | -0.0 | 0.0 | -0.0 | 0.0 | -0.0 | 0.0 | -0.0 | -0.0 | -0.0 | 0.0 | 0.0 | -0.0 | 0.1 |
Condit. Reinf. active minus inactive responses | 0.0 | 0.0 | 0.1 | -0.0 | 0.0 | -0.1 | -0.0 | -0.1 | 0.1 | 0.1 | -0.0 | 0.0 | 0.1 | -0.0 | -0.1 | -0.3 | 0.0 | -0.0 | 0.0 | -0.0 | 0.0 | -0.0 | 0.0 | 0.0 | -0.0 | 0.0 | -0.0 | 0.0 | -0.1 |
Incentive salience index mean | 0.0 | 0.0 | 0.0 | -0.1 | 0.1 | 0.0 | -0.1 | -0.0 | 0.1 | 0.1 | -0.1 | -0.1 | -0.0 | -0.1 | -0.1 | -0.1 | 0.1 | -0.1 | 0.1 | 0.0 | -0.0 | -0.1 | -0.1 | -0.0 | 0.1 | -0.1 | -0.1 | 0.1 | 0.0 |
Pavlov. Cond. index score | 0.0 | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | 0.0 | -0.1 | -0.1 | -0.1 | 0.1 | 0.1 | -0.1 | 0.0 | 0.1 | 0.2 | -0.1 | 0.1 | -0.1 | 0.0 | -0.0 | 0.1 | 0.0 | -0.0 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 |
Pavlov. Cond. latency score | 0.0 | 0.0 | 0.0 | -0.1 | 0.1 | 0.1 | -0.1 | -0.0 | -0.0 | -0.0 | -0.0 | -0.0 | -0.2 | -0.1 | 0.0 | 0.2 | 0.0 | -0.0 | 0.0 | 0.1 | -0.1 | -0.0 | -0.1 | -0.1 | 0.1 | -0.1 | -0.0 | 0.0 | 0.2 |
Pavlov. Cond. lever contacts | 0.0 | 0.0 | 0.0 | -0.1 | 0.1 | 0.1 | -0.1 | -0.0 | -0.0 | -0.0 | -0.0 | -0.0 | -0.1 | -0.0 | 0.0 | 0.1 | 0.1 | -0.0 | 0.1 | -0.0 | 0.0 | -0.0 | -0.0 | 0.0 | 0.1 | -0.1 | -0.0 | 0.0 | 0.1 |
Pavlov. Cond. lever-magazine prob. diff. | 0.0 | 0.0 | 0.1 | 0.0 | -0.0 | 0.1 | 0.0 | -0.1 | -0.1 | -0.1 | 0.1 | 0.1 | -0.1 | 0.0 | 0.1 | 0.2 | -0.1 | 0.1 | -0.1 | 0.0 | -0.0 | 0.1 | 0.0 | -0.0 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 |
Bone: cortical thickness | 0.0 | 0.0 | 0.1 | 0.0 | -0.0 | 0.2 | 0.0 | -0.1 | 0.0 | 0.0 | -0.1 | -0.1 | -0.2 | -0.1 | -0.0 | 0.4 | 0.0 | -0.1 | -0.0 | 0.3 | -0.3 | -0.1 | -0.1 | -0.3 | 0.0 | -0.0 | -0.1 | 0.1 | 0.2 |
Bone: final moment | 0.0 | 0.0 | 0.0 | 0.2 | -0.2 | -0.1 | 0.2 | -0.1 | -0.1 | -0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | -0.1 | 0.1 | -0.1 | -0.1 | 0.1 | 0.1 | 0.1 | 0.1 | -0.1 | 0.1 | 0.1 | -0.1 | -0.1 |
Bone: trabecular number | 0.0 | 0.1 | 0.1 | 0.2 | -0.2 | -0.1 | 0.2 | -0.3 | -0.3 | -0.2 | 0.2 | 0.2 | 0.1 | 0.3 | 0.2 | 0.3 | -0.2 | 0.2 | -0.3 | -0.2 | 0.2 | 0.2 | 0.2 | 0.2 | -0.3 | 0.3 | 0.2 | -0.2 | -0.1 |
Bone: trabecular spacing | 0.0 | 0.0 | 0.3 | 0.1 | -0.1 | -0.2 | 0.1 | -0.1 | -0.1 | -0.1 | 0.1 | 0.1 | 0.2 | 0.0 | 0.1 | -0.6 | -0.1 | 0.1 | -0.1 | -0.1 | 0.1 | 0.1 | 0.1 | 0.1 | -0.1 | 0.1 | 0.1 | -0.1 | -0.3 |
Bone: trabecular thickness | 0.0 | 0.0 | 0.2 | 0.3 | -0.3 | -0.0 | 0.2 | -0.2 | -0.2 | -0.2 | 0.2 | 0.2 | 0.0 | 0.3 | 0.2 | 0.5 | -0.2 | 0.2 | -0.2 | -0.1 | 0.1 | 0.2 | 0.2 | 0.1 | -0.2 | 0.2 | 0.2 | -0.2 | -0.0 |
Time to tail flick, test, after self-admin | 0.0 | 0.0 | 0.1 | -0.2 | 0.2 | 0.1 | -0.1 | 0.2 | 0.0 | 0.2 | -0.2 | -0.2 | -0.1 | -0.4 | -0.4 | -0.2 | 0.2 | -0.2 | 0.2 | 0.0 | -0.0 | -0.2 | -0.2 | -0.0 | 0.2 | -0.2 | -0.2 | 0.2 | 0.1 |
Fecal boli incidents, locomotor time 1 | 0.0 | 0.0 | 0.1 | -0.0 | 0.0 | 0.2 | -0.0 | 0.2 | -0.1 | 0.0 | -0.1 | -0.1 | -0.1 | 0.0 | -0.1 | 0.1 | 0.0 | -0.1 | 0.0 | 0.3 | -0.3 | -0.1 | -0.1 | -0.3 | 0.0 | -0.0 | -0.1 | 0.1 | 0.1 |
Rest time, locomotor task time 1 | 0.0 | 0.1 | 0.9 | 0.0 | -0.0 | 0.1 | 0.0 | 0.0 | 0.3 | 0.1 | -0.1 | -0.1 | -0.1 | 0.0 | -0.4 | 1.0 | 0.0 | -0.1 | 0.0 | -0.0 | 0.0 | -0.2 | -0.1 | 0.0 | 0.0 | -0.0 | -0.1 | 0.1 | 0.1 |
Locomotion in novel chamber post-restriction | 0.0 | 0.0 | 0.3 | 0.1 | -0.1 | 0.3 | 0.1 | -0.0 | -0.1 | -0.1 | 0.0 | 0.0 | -0.3 | -0.0 | 0.4 | 0.5 | -0.0 | 0.0 | -0.1 | -0.1 | 0.1 | 0.1 | -0.1 | -0.2 | -0.0 | 0.0 | 0.0 | -0.0 | 0.3 |
Run reversals in cocaine runway, females | 0.0 | 0.0 | 0.4 | 0.0 | -0.0 | 0.3 | 0.0 | -0.1 | 0.0 | -0.1 | 0.0 | -0.0 | -0.3 | -0.1 | 0.2 | 0.6 | -0.0 | 0.0 | -0.0 | 0.1 | -0.1 | 0.0 | -0.0 | -0.0 | -0.0 | 0.0 | 0.0 | -0.0 | 0.3 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.