Hub : Genes

Polr3f

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007548 0.07 0.04 1.8e-08 0.02 0.05 0.04 0.04 3.4e-03 3.4e-06 9.1e-05 8.7e-05
2 Adipose mRNA stability ENSRNOG00000007548 0.41 0.14 0.0e+00 0.24 0.23 0.24 0.24 9.0e-27 2.5e-25 3.1e-26 2.7e-26
3 BLA mRNA stability ENSRNOG00000007548 0.28 0.11 1.7e-14 0.23 0.27 0.24 0.24 8.0e-13 5.7e-15 3.3e-13 3.7e-13
4 Brain mRNA stability ENSRNOG00000007548 0.29 0.11 0.0e+00 0.22 0.29 0.29 0.29 3.0e-20 7.6e-27 4.2e-27 3.8e-27
5 IL gene expression ENSRNOG00000007548 0.3 0.18 3.7e-03 0.1 0.05 0.03 0.06 2.8e-03 2.2e-02 7.3e-02 1.3e-02
6 IL mRNA stability ENSRNOG00000007548 0.46 0.14 1.2e-08 0.27 0.28 0.28 0.28 3.2e-07 2.6e-07 2.2e-07 2.0e-07
7 LHb mRNA stability ENSRNOG00000007548 0.44 0.29 2.9e-03 0.1 0.04 0.03 0.05 2.5e-03 4.2e-02 7.7e-02 2.7e-02
8 Liver gene expression ENSRNOG00000007548 0.2 0.08 0.0e+00 0.17 0.19 0.19 0.19 4.2e-18 1.3e-20 3.4e-20 2.1e-20
9 Liver mRNA stability ENSRNOG00000007548 0.25 0.1 0.0e+00 0.21 0.22 0.19 0.22 9.5e-23 1.0e-23 3.9e-21 2.0e-23
10 NAcc mRNA stability ENSRNOG00000007548 0.19 0.08 7.2e-13 0.15 0.19 0.17 0.17 1.9e-11 3.6e-14 1.9e-12 1.4e-12
11 OFC mRNA stability ENSRNOG00000007548 0.45 0.16 7.8e-07 0.18 0.16 0.15 0.15 5.5e-05 1.2e-04 2.0e-04 2.4e-04
12 PL gene expression ENSRNOG00000007548 0.09 0.07 4.5e-04 0.02 0.04 0.04 0.03 1.0e-02 4.1e-04 2.3e-04 1.3e-03
13 PL mRNA stability ENSRNOG00000007548 0.25 0.1 0.0e+00 0.24 0.29 0.29 0.28 1.7e-18 2.2e-22 2.6e-22 1.0e-21

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.44.623.72.5-0.80.42.60.01.8-0.43.14.90.8-0.42.70.8
BMI without tail1.22.510.00.8-1.8-1.00.81.30.3-1.61.43.2-0.6-1.62.9-0.6
Body weight1.46.029.21.7-2.0-0.82.11.71.1-1.82.65.4-0.4-1.84.3-0.5
Epididymis fat weight1.02.411.11.0-1.1-0.61.40.90.6-1.21.63.3-0.2-1.22.9-0.4
Glucose0.81.22.7-0.9-1.0-1.4-0.51.2-0.9-1.2-0.70.3-1.2-1.21.6-1.3
Heart weight0.71.03.60.2-1.2-0.70.20.9-0.1-1.20.51.5-0.6-1.21.9-0.6
Left kidney weight0.30.93.10.4-1.1-0.60.40.90.2-0.80.71.8-0.5-0.81.7-0.4
Right kidney weight0.30.83.20.2-1.1-0.70.31.0-0.0-0.80.51.6-0.5-0.81.8-0.5
Tail length0.72.13.1-1.2-1.7-1.8-0.91.8-1.2-1.8-0.90.3-1.5-1.81.5-1.8
Length with tail0.72.66.6-0.6-1.9-1.7-0.42.1-0.7-2.0-0.21.5-1.5-2.02.6-1.6
Length without tail0.20.52.20.4-0.5-0.30.60.60.4-0.50.71.5-0.2-0.51.4-0.1
Liver weight, left0.00.00.0-0.10.0-0.00.2-0.1-0.1-0.00.00.10.0-0.00.1-0.1
Liver weight, right0.00.10.30.10.20.20.1-0.60.30.30.10.00.40.3-0.30.1
Parametrial fat weight2.14.123.81.9-1.0-0.82.00.81.3-0.92.64.90.1-0.93.1-0.1
Retroperitoneal fat weight2.47.941.73.0-0.80.13.50.72.2-0.83.96.50.8-0.84.10.6
Intraocular pressure1.92.74.6-2.1-1.4-1.3-2.01.1-1.7-1.4-2.1-2.1-1.5-1.40.7-1.7
Extensor digitorum longus weight0.10.51.0-0.5-0.9-0.8-0.30.7-0.5-0.8-0.30.4-0.7-0.81.0-0.8
Soleus weight0.10.31.0-0.4-0.8-0.4-0.30.6-0.4-0.6-0.30.0-0.5-0.61.0-0.5
Tibialis anterior weight0.20.62.80.7-0.60.00.90.50.4-0.40.91.70.1-0.41.40.0
Tibia length0.51.37.21.20.3-0.01.3-0.31.30.41.62.70.60.41.20.3
Number of licking bursts0.10.10.60.50.10.80.4-0.10.50.10.40.10.40.10.00.5
Food consumed during 24 hour testing period0.00.00.1-0.00.00.10.2-0.00.30.00.10.20.10.00.3-0.1
Times rat made contact with spout0.60.63.30.5-0.5-0.50.60.50.3-0.50.81.8-0.2-0.51.4-0.3
Mean time between licks in bursts0.10.10.3-0.2-0.3-0.0-0.40.3-0.4-0.3-0.3-0.6-0.3-0.30.3-0.1
Mean num. licks in bursts0.20.31.1-0.3-0.3-1.1-0.10.3-0.2-0.3-0.00.8-0.5-0.30.8-0.8
Std. dev. time between licks in bursts0.10.10.9-0.30.10.3-0.4-0.0-0.10.0-0.5-1.00.00.0-0.20.1
Water consumed over 24 hours1.31.52.2-1.2-1.3-1.5-1.11.3-1.1-1.3-1.0-0.2-1.3-1.31.2-1.5
Indifference point 0 sec2.64.25.7-2.3-2.0-2.3-1.92.0-2.3-1.9-2.2-1.3-2.3-1.91.5-2.4
Indifference point AUC0.30.31.30.30.60.60.0-0.60.30.60.1-0.50.50.6-1.10.6
Indifference point function ln k0.91.32.0-1.4-1.0-1.3-1.11.0-1.2-1.1-1.2-0.7-1.2-1.10.7-1.4
Indifference point function log k0.91.32.0-1.4-1.0-1.3-1.11.0-1.2-1.1-1.2-0.7-1.2-1.10.7-1.4
Delay discounting total patch changes 0 sec2.43.95.0-2.2-1.9-2.1-2.01.9-2.2-1.8-2.1-1.4-2.2-1.81.4-2.2
Delay discounting total patch changes 12 sec0.00.00.20.00.0-0.10.20.00.20.10.10.40.00.10.2-0.1
Delay discounting total patch changes 18 sec1.11.42.3-1.4-0.9-1.0-1.40.9-1.5-1.0-1.5-1.4-1.2-1.00.5-1.2
Delay discounting total patch changes 24 sec0.20.30.5-0.5-0.6-0.4-0.50.5-0.6-0.7-0.5-0.4-0.5-0.7-0.0-0.5
Delay discounting total patch changes 6 sec0.60.91.1-1.0-0.9-0.7-0.80.9-1.1-1.0-1.0-0.8-0.9-1.01.0-1.0
Delay discounting time to switch 0 sec0.71.13.21.30.70.71.5-0.61.10.71.51.80.90.70.10.8
Delay discounting water rate 0 sec0.50.73.7-1.0-0.2-0.2-1.30.1-0.8-0.3-1.3-1.9-0.5-0.3-0.6-0.4
Delay discounting water rate 12 sec0.71.03.9-0.31.21.0-0.3-1.00.11.0-0.7-2.00.71.0-1.60.7
Delay discounting water rate 18 sec2.43.214.8-2.4-0.1-0.6-2.40.0-1.5-0.2-2.8-3.8-0.9-0.2-1.6-1.1
Delay discounting water rate 24 sec1.92.66.9-2.1-1.0-1.1-2.20.9-1.7-1.2-2.3-2.6-1.3-1.2-0.1-1.4
Delay discounting water rate 6 sec0.81.26.7-1.30.1-0.1-1.4-0.1-0.90.1-1.6-2.6-0.40.1-1.1-0.4
Locomotor activity0.00.10.20.2-0.3-0.10.10.10.1-0.20.30.5-0.1-0.20.4-0.0
Locomotor testing distance0.00.00.1-0.1-0.1-0.1-0.2-0.0-0.1-0.1-0.2-0.3-0.1-0.1-0.1-0.1
Locomotor testing rearing0.10.21.00.1-0.6-0.2-0.10.6-0.2-0.60.10.3-0.4-0.61.0-0.1
Light reinforcement 11.32.43.0-1.6-1.7-1.5-1.51.7-1.4-1.7-1.5-0.9-1.6-1.71.1-1.7
Light reinforcement 23.24.35.9-1.9-2.4-2.4-2.22.2-2.0-2.4-1.8-0.8-2.3-2.41.0-2.2
Reaction time number correct2.53.65.5-2.0-1.9-1.5-2.31.9-1.9-2.1-2.1-1.9-1.9-2.10.8-1.7
Reaction time mean minus median0.50.62.80.4-0.6-0.60.50.6-0.0-0.70.71.7-0.3-0.71.6-0.3
Reaction time mean minus median AUC0.91.24.4-0.0-1.2-1.00.01.3-0.4-1.30.31.4-0.8-1.32.1-0.8
Reaction time num false alarms0.50.72.9-1.00.5-0.3-1.0-0.5-0.40.5-1.1-1.7-0.20.5-1.2-0.4
Reaction time num false alarms AUC0.40.62.4-0.80.4-0.1-0.9-0.4-0.30.5-1.0-1.6-0.10.5-1.2-0.2
Reaction time trials correct on left2.53.65.5-2.0-1.9-1.5-2.31.9-1.9-2.1-2.1-1.9-1.9-2.10.8-1.7
Reaction time trials on left2.73.95.8-2.0-2.0-1.6-2.42.0-2.0-2.2-2.1-1.9-2.0-2.20.9-1.8
Reaction time mean0.81.14.70.6-0.7-0.50.90.70.2-0.71.02.2-0.2-0.72.2-0.4
Reaction time mean AUC0.60.84.10.6-0.5-0.40.80.50.3-0.61.02.0-0.1-0.61.8-0.2
Median of all reaction times0.60.94.00.6-0.6-0.40.90.50.3-0.50.92.0-0.1-0.52.0-0.3
Reaction time omissions0.81.14.7-0.1-1.4-0.7-0.21.2-0.6-1.30.00.8-0.8-1.32.2-0.7
Reaction time false alarm rate0.40.61.70.01.00.40.1-1.10.41.2-0.1-0.60.61.2-1.30.4
Reaction time premature initiation rate0.10.20.4-0.7-0.2-0.5-0.50.3-0.3-0.1-0.6-0.4-0.4-0.1-0.4-0.6
Reaction time premature initiations1.11.62.8-1.6-1.0-1.2-1.71.1-1.2-1.0-1.6-1.4-1.3-1.0-0.2-1.4
Std. dev. reaction times0.60.83.50.5-0.6-0.50.70.60.1-0.70.81.9-0.2-0.71.9-0.3
Reaction time trials completed2.73.95.8-2.0-2.0-1.6-2.42.0-2.0-2.2-2.1-1.9-2.0-2.20.9-1.8
Reaction time trials AUC3.55.07.0-2.3-2.3-1.9-2.62.3-2.3-2.4-2.4-2.0-2.3-2.41.2-2.1
Social response proportion1.01.05.41.2-0.1-0.01.20.30.9-0.21.52.30.3-0.21.30.4
Social responses0.10.10.30.30.10.10.30.10.50.00.30.50.20.00.10.1
Social time0.40.52.01.1-0.10.40.7-0.11.0-0.01.11.40.4-0.00.70.6
Conditioned locomotion1.31.52.1-1.3-1.3-1.4-1.21.3-1.3-1.3-1.3-0.8-1.4-1.30.7-1.4
Cocaine response after cond. corrected1.11.22.8-1.6-0.7-0.8-1.20.7-1.2-0.7-1.6-1.7-1.0-0.7-0.1-1.1
Cocaine response after cond. not corrected1.61.84.8-1.9-0.8-0.8-1.60.8-1.4-0.8-2.0-2.2-1.1-0.8-0.0-1.3
Cocaine response before conditioning0.00.00.2-0.10.00.2-0.3-0.10.00.1-0.2-0.50.00.1-0.00.1
Saline control response3.54.77.2-1.8-2.4-2.7-1.72.4-1.9-2.3-1.50.1-2.4-2.32.7-2.5
Condit. Reinf. active minus inactive responses0.70.92.4-0.4-1.1-1.3-0.31.1-0.6-1.0-0.20.9-1.0-1.01.6-1.0
Condit. Reinf. active-inactive response ratio0.60.62.0-0.1-1.0-0.8-0.11.0-0.3-0.90.10.9-0.6-0.91.4-0.6
Condit. Reinf. active responses0.20.21.20.60.2-0.00.6-0.20.50.30.71.10.30.30.30.2
Condit. Reinf. inactive responses1.41.72.51.31.51.21.1-1.51.31.61.20.71.41.6-1.31.3
Condit. Reinf. lever presses0.81.14.10.5-1.2-0.80.41.1-0.0-1.00.81.9-0.6-1.02.0-0.5
Condit. Reinf. lever reinforcers received0.20.31.60.6-0.1-0.20.50.10.30.10.71.30.10.10.60.1
Pavlov. Cond. lever latency0.81.16.0-0.90.60.2-1.1-0.6-0.70.6-1.3-2.5-0.10.6-1.80.0
Pavlov. Cond. magazine entry latency3.03.56.9-1.2-2.2-2.1-0.82.3-1.5-2.3-0.80.8-1.9-2.32.6-2.0
Pavlov. Cond. change in total contacts1.11.57.81.3-0.2-0.01.50.20.9-0.31.72.80.4-0.31.80.3
Pavlov. Cond. index score1.21.65.70.4-1.3-0.90.71.30.0-1.30.92.3-0.6-1.32.4-0.7
Pavlov. Cond. latency score0.81.14.20.5-1.0-0.60.71.00.1-1.00.82.0-0.4-1.02.0-0.4
Pavlov. Cond. lever contacts0.71.05.10.8-0.7-0.21.00.70.5-0.61.22.3-0.0-0.61.6-0.1
Pavlov. Cond. magazine entry number1.31.64.60.31.41.4-0.1-1.50.61.5-0.1-1.61.11.5-2.21.2
Pavlov. Cond. intertrial magazine entries0.60.82.20.40.91.20.0-0.90.60.90.1-0.90.80.9-1.51.0
Pavlov. Cond. lever-magazine prob. diff.1.11.46.50.8-0.9-0.51.00.90.3-0.91.22.5-0.3-0.92.2-0.3
Pavlov. Cond. response bias1.11.65.30.1-1.4-1.10.31.4-0.2-1.40.52.0-0.8-1.42.3-0.9
Conditioned reinforcement - actives1.91.93.2-1.8-0.9-1.5-1.61.3-1.4-0.9-1.8-1.4-1.5-0.90.7-1.6
Conditioned reinforcement - inactives2.93.35.6-2.4-1.4-1.8-2.11.5-2.1-1.4-2.3-1.9-1.9-1.40.3-2.1
Conditioned locomotion0.10.10.50.00.20.2-0.2-0.1-0.00.2-0.2-0.60.10.2-0.70.2
Intermittent access intake day 1-15 change1.11.12.0-0.9-1.0-1.4-0.61.3-0.9-1.0-0.60.3-1.2-1.01.3-1.3
Intermittent access intake escalation1.01.01.8-1.0-0.9-1.3-0.71.3-0.9-0.9-0.80.1-1.2-0.91.2-1.2
Intermittent access intake escalation 21.31.32.8-0.9-1.1-1.3-0.71.4-0.9-1.1-0.70.3-1.3-1.11.7-1.3
Intermitt. access day 1 inactive lever presses0.10.10.2-0.40.4-0.0-0.00.3-0.00.4-0.4-0.4-0.10.40.3-0.1
Intermitt. access day 15 inactive lever presses2.32.54.2-1.8-1.4-2.1-1.21.7-1.7-1.4-1.4-0.2-1.8-1.41.6-2.1
Intermitt. access escalation Index1.21.12.5-0.1-1.3-1.3-0.31.3-0.6-1.30.11.1-1.1-1.31.6-0.9
Intermittent access day 1 total infusions0.20.20.30.30.60.00.3-0.50.40.60.40.40.40.6-0.50.2
Intermittent access day 15 total infusions0.30.31.1-0.6-0.3-1.1-0.30.6-0.4-0.3-0.30.4-0.7-0.30.5-0.8
Intermittent access terminal intake (last 3 days)0.10.10.6-0.20.2-0.70.20.20.00.20.00.6-0.30.20.2-0.5
Intermittent access total infusions0.20.20.7-0.3-0.3-0.8-0.10.5-0.3-0.3-0.10.5-0.5-0.30.4-0.6
Intermittent access day 1 locomotion1.61.62.41.21.41.11.0-1.41.31.41.20.61.31.4-1.61.3
Intermittent access day 15 total locomotion0.00.00.10.0-0.3-0.2-0.10.1-0.1-0.30.00.2-0.1-0.30.1-0.2
Intermittent access total locomotion0.60.61.40.70.90.70.6-0.90.80.90.60.30.80.9-1.20.8
Intermittent access standard deviation0.60.61.1-1.1-0.5-1.0-0.90.8-0.8-0.5-1.0-0.7-0.9-0.50.0-1.0
Cocaine induced anxiety0.70.81.3-1.1-0.6-1.1-1.10.6-0.9-0.6-1.0-0.8-1.0-0.60.1-1.0
Post-drug Anxiety0.91.02.1-0.6-1.1-1.2-0.41.2-0.7-1.1-0.30.7-1.0-1.11.4-1.2
Baseline Anxiety0.70.73.10.2-0.9-0.50.40.9-0.1-0.90.51.4-0.4-0.91.8-0.4
Lifetime Intake0.30.30.8-0.4-0.6-0.9-0.30.6-0.5-0.6-0.30.3-0.6-0.60.5-0.7
Incentive Sensitization - Responses0.60.61.0-0.6-1.0-0.8-0.80.7-0.8-1.0-0.6-0.2-0.8-1.00.8-0.8
Incentive Sensitization - Breakpoint0.70.71.1-0.6-1.0-0.9-0.70.8-0.8-1.0-0.5-0.1-0.8-1.00.9-0.8
Progressive ratio test 1 active lever presses0.20.20.30.40.50.00.5-0.30.40.50.40.60.30.5-0.30.2
Progressive ratio test 1 breakpoint0.40.40.80.70.70.30.9-0.50.70.70.70.80.60.7-0.40.5
Progressive ratio test 1 inactive lever presses1.21.32.0-1.3-1.2-1.3-1.01.3-1.2-1.2-1.1-0.4-1.3-1.20.8-1.4
Progressive ratio test 2 active lever presses0.00.00.0-0.10.1-0.10.1-0.20.10.10.00.20.00.10.1-0.1
Progressive ratio test 2 breakpoint0.00.00.10.10.2-0.10.2-0.30.20.20.20.30.20.2-0.10.0
Progressive ratio test 2 inactive lever presses2.42.84.1-1.5-2.0-2.0-1.51.7-1.6-2.0-1.2-0.2-1.8-2.01.4-2.0
Total sessions with >9 infusions0.20.20.90.4-0.4-0.20.40.40.1-0.40.51.0-0.1-0.40.7-0.0
Short access day 1 total inactive lever presses4.75.26.7-2.5-2.1-2.4-2.42.6-2.4-2.1-2.4-1.6-2.6-2.11.6-2.5
Short access day 10 total inactive lever presses1.31.53.4-0.9-1.3-1.2-0.81.8-1.0-1.3-0.8-0.0-1.3-1.31.9-1.2
Short access day 1 total infusions1.31.31.8-1.2-1.2-1.2-1.31.1-1.3-1.2-1.2-0.9-1.2-1.20.4-1.2
Short access day 10 total infusions0.10.10.3-0.2-0.2-0.5-0.20.5-0.2-0.2-0.20.2-0.4-0.20.2-0.4
Short access total infusions0.20.20.4-0.1-0.6-0.6-0.10.5-0.4-0.60.00.5-0.4-0.60.6-0.4
Short access day 1 locomotion0.10.10.30.2-0.5-0.30.00.4-0.1-0.50.30.5-0.2-0.50.5-0.1
Short access day 10 total locomotion0.20.21.1-0.20.50.4-0.0-0.30.30.5-0.2-0.70.30.5-1.10.2
Short access total locomotion0.80.81.41.20.81.00.9-0.81.00.81.00.61.00.8-0.81.1
Compulsive drug intake0.60.61.6-1.0-0.3-0.5-0.80.8-1.2-0.3-1.1-1.3-0.7-0.30.1-0.6
One hour access (0.3 mA shock)0.20.20.5-0.6-0.1-0.5-0.50.4-0.6-0.1-0.7-0.7-0.5-0.1-0.0-0.4
One hour access (shock baseline)0.10.10.30.30.30.10.4-0.30.50.30.40.60.30.3-0.00.2
Number of responses in last shaping day1.11.11.8-1.3-1.0-0.9-1.10.7-1.2-1.0-1.3-1.0-1.0-1.00.3-1.2
Context. condit. distance diff. score0.30.31.4-0.3-0.8-0.4-0.30.6-0.4-0.5-0.2-0.0-0.5-0.51.2-0.4
Locomotion velocity, session 10.70.71.5-1.0-0.3-1.2-1.20.4-0.8-0.4-1.1-1.0-0.8-0.4-0.6-0.9
Locomotion distance, session 10.81.14.8-1.10.6-0.1-1.0-0.6-0.50.6-1.3-2.2-0.00.6-1.8-0.3
Locomotion velocity, session 21.41.65.00.12.00.80.1-1.60.71.6-0.1-1.01.01.6-2.20.8
Locomotion distance, session 22.02.98.4-2.3-0.6-1.3-2.40.9-1.8-0.9-2.5-2.9-1.5-0.9-0.5-1.5
Locomotion velocity, session 30.50.63.1-0.70.50.2-0.8-0.4-0.40.4-0.9-1.80.00.4-1.30.0
Locomotion distance, session 30.30.41.0-0.00.90.6-0.1-0.60.20.6-0.2-0.90.50.6-1.00.5
Stereotopy head waving bouts, day 30.10.10.3-0.3-0.2-0.5-0.20.3-0.4-0.3-0.30.0-0.4-0.3-0.2-0.4
Stereotopy head waving duration, day 30.10.10.3-0.2-0.4-0.5-0.20.4-0.3-0.3-0.10.2-0.4-0.3-0.0-0.4
Locomotion velocity, session 70.50.61.7-1.2-0.1-0.7-0.90.1-0.7-0.1-1.2-1.3-0.5-0.1-0.2-0.8
Locomotion distance, session 70.70.91.9-1.4-0.7-1.1-0.90.7-0.9-0.7-1.2-0.9-0.9-0.70.4-1.2
Stereotopy head waving bouts, day 70.00.00.30.00.0-0.10.10.2-0.0-0.20.10.3-0.1-0.20.5-0.1
Stereotopy head waving duration, day 70.00.10.20.20.40.30.1-0.20.20.20.1-0.20.20.2-0.20.3
Locomotion velocity, session 80.81.01.8-1.3-0.6-1.3-1.30.6-1.1-0.6-1.3-1.2-1.0-0.60.0-1.2
Locomotion distance, session 81.21.74.6-1.8-0.8-1.1-1.80.6-1.4-0.6-1.9-2.1-1.2-0.60.2-1.3
Degree of sensitization distance1.21.22.2-1.1-1.4-1.4-0.71.1-0.9-1.0-0.80.1-1.1-1.01.3-1.5
Degree of sensitization stereotypy0.20.20.50.50.20.30.50.00.4-0.00.50.70.2-0.00.70.3
Condit. Reinf. active minus inactive responses0.20.20.4-0.3-0.50.0-0.30.6-0.4-0.6-0.3-0.3-0.4-0.60.6-0.2
Condit. Reinf. active-inactive response ratio0.10.20.3-0.3-0.50.1-0.30.5-0.3-0.5-0.3-0.4-0.3-0.50.5-0.2
Condit. Reinf. active responses0.10.10.2-0.2-0.10.1-0.20.3-0.3-0.3-0.3-0.4-0.2-0.30.2-0.1
Condit. Reinf. inactive responses0.00.00.2-0.20.3-0.3-0.1-0.1-0.10.1-0.1-0.0-0.00.1-0.4-0.2
Incentive salience index mean0.50.51.30.50.81.20.4-0.80.60.80.3-0.40.80.8-0.80.9
Condit. Reinf. lever presses2.53.35.21.62.02.31.5-2.01.82.01.40.32.12.0-1.72.1
Time in familiar zone, hab. session 11.81.72.71.31.61.51.4-1.31.31.31.30.81.51.3-0.61.4
Time in novel zone, hab. session 11.81.73.5-1.0-1.9-1.5-1.01.5-1.1-1.5-0.9-0.2-1.5-1.51.3-1.4
Total zone transitions, hab. session 10.30.52.5-0.40.50.1-0.3-0.70.00.7-0.5-1.00.30.7-1.60.1
Total locomotion distance, hab. session 10.50.73.8-0.70.70.0-0.6-0.8-0.30.8-0.8-1.40.20.8-2.0-0.0
Locomotion velocity, hab. session 10.60.94.7-0.50.90.3-0.5-1.0-0.11.0-0.7-1.60.31.0-2.20.2
Time in familiar zone, hab. session 20.30.30.5-0.5-0.3-0.5-0.60.5-0.7-0.5-0.5-0.4-0.6-0.50.4-0.5
Time in novel zone, hab. session 20.10.10.50.1-0.5-0.20.20.30.2-0.40.20.7-0.1-0.40.5-0.2
Total zone transitions, hab. session 20.70.91.3-1.0-1.1-1.1-1.01.0-0.9-1.0-0.9-0.5-1.0-1.00.6-1.1
Total locomotion distance, hab. session 22.53.44.3-1.9-1.8-2.0-2.11.8-2.0-1.8-1.9-1.4-2.0-1.81.2-2.0
Locomotion velocity, hab. session 21.92.53.9-1.8-1.4-1.7-2.01.4-1.8-1.4-1.9-1.6-1.7-1.40.6-1.7
Novel to familiar place preference ratio0.10.10.7-0.2-0.8-0.0-0.00.5-0.3-0.5-0.10.0-0.2-0.50.2-0.2
Novelty place preference0.10.10.50.1-0.70.20.10.4-0.1-0.40.10.1-0.1-0.40.10.0
Time in novel zone, NPP test0.20.21.1-0.0-1.0-0.00.10.7-0.2-0.70.10.3-0.3-0.70.5-0.2
Total zone transitions, NPP test0.20.31.0-0.7-0.1-0.3-0.7-0.1-0.30.1-0.7-1.0-0.20.1-0.7-0.4
Total locomotion distance, NPP test1.52.13.5-1.8-1.2-1.4-1.91.1-1.6-1.1-1.9-1.8-1.4-1.10.4-1.5
Locomotion velocity, NPP test1.11.63.8-1.7-0.8-1.1-1.70.7-1.4-0.7-1.8-1.9-1.2-0.7-0.1-1.3
Pavlov. Cond. lever latency3.44.37.1-1.5-2.2-2.7-1.42.5-2.0-2.5-1.20.5-2.4-2.51.9-2.3
Pavlov. Cond. magazine entry latency1.41.82.71.51.31.61.3-1.41.41.41.30.61.51.4-1.01.7
Pavlov. Cond. change in total contacts4.44.78.51.72.42.91.6-2.52.12.51.3-0.42.52.5-1.82.6
Pavlov. Cond. index score4.15.38.12.12.42.91.9-2.62.32.61.80.32.62.6-1.92.7
Pavlov. Cond. latency score3.84.87.91.92.42.81.6-2.52.12.51.5-0.22.52.5-2.02.6
Pavlov. Cond. lever contacts3.44.05.91.62.22.41.6-2.42.02.41.40.02.32.4-1.52.2
Pavlov. Cond. magazine entry number2.12.63.6-1.7-1.6-1.9-1.61.6-1.7-1.6-1.6-0.9-1.8-1.60.9-1.9
Pavlov. Cond. intertrial magazine entries5.66.78.7-2.7-2.6-2.8-2.72.6-3.0-2.6-2.7-1.7-2.9-2.61.5-2.8
Pavlov. Cond. lever-magazine prob. diff.4.96.29.22.32.63.02.2-2.82.52.82.00.42.82.8-2.02.9
Pavlov. Cond. response bias3.13.85.71.92.02.41.9-2.22.12.11.70.62.32.1-1.32.2
Bone: apparent density0.10.10.6-0.2-0.4-0.0-0.30.2-0.1-0.2-0.3-0.4-0.2-0.20.8-0.2
Bone surface0.10.21.3-0.0-0.5-0.60.10.3-0.0-0.30.10.6-0.3-0.31.1-0.4
Bone volume0.40.62.1-0.6-0.9-0.8-0.60.8-0.5-0.8-0.5-0.1-0.8-0.81.4-0.9
Bone: connectivity density0.00.00.2-0.00.20.1-0.0-0.30.10.3-0.1-0.40.10.30.00.1
Bone: cortical apparent density1.11.42.01.11.21.41.0-1.41.11.41.00.21.31.4-1.01.4
Bone: cortical area0.20.40.60.60.50.40.6-0.70.80.60.70.70.60.6-0.40.5
Bone: cortical porosity0.20.20.70.60.30.10.4-0.00.30.00.70.80.20.0-0.70.4
Bone: cortical porosity0.20.21.10.70.20.10.5-0.00.40.00.81.00.20.0-0.40.4
Bone: cortical thickness1.52.53.11.71.61.51.5-1.61.71.61.71.11.61.6-1.51.8
Bone: cortical thickness0.91.13.10.51.21.10.4-1.30.81.20.3-0.71.01.2-1.81.0
Bone: cortical tissue density0.81.01.51.01.01.20.9-1.20.91.20.80.21.11.2-0.81.2
Bone: elastic displacement0.91.01.31.01.10.61.0-1.11.11.11.11.01.01.1-0.90.9
Bone: elastic work1.41.84.71.70.90.91.7-0.91.60.91.92.21.20.9-0.11.1
Bone: endosteal estimation1.53.310.0-1.1-2.4-1.9-0.82.1-1.1-2.1-0.61.0-1.7-2.13.2-1.9
Bone: endosteal perimeter1.63.36.0-1.6-2.3-2.0-1.41.9-1.5-2.0-1.3-0.1-1.9-2.02.4-2.0
Bone: final force0.10.20.90.60.00.30.6-0.10.70.10.70.90.30.10.30.3
Bone: final moment0.10.20.70.50.00.30.5-0.10.60.10.60.80.30.10.30.2
Bone: marrow area1.63.410.2-1.1-2.4-1.9-0.82.1-1.1-2.1-0.71.0-1.7-2.13.2-2.0
Bone: maximum diameter0.51.02.4-0.7-1.3-1.1-0.51.1-0.6-1.1-0.40.6-0.9-1.11.6-1.2
Bone: maximum force0.10.10.50.2-0.40.00.20.20.2-0.30.30.6-0.1-0.30.7-0.1
Bone: maximum moment0.00.10.40.2-0.20.10.30.10.3-0.10.30.60.0-0.10.60.0
Bone: minimum diameter0.10.31.20.1-0.6-0.50.10.40.1-0.40.30.9-0.3-0.41.1-0.4
Bone: periosteal estimation0.51.13.7-0.5-1.4-1.1-0.31.1-0.4-1.1-0.11.0-0.9-1.11.9-1.1
Bone: periosteal perimeter0.50.81.6-0.7-1.3-1.1-0.71.0-0.6-1.0-0.50.2-0.9-1.01.3-1.0
Bone: post-yield work0.20.30.5-0.6-0.7-0.5-0.40.6-0.7-0.6-0.6-0.3-0.6-0.60.6-0.6
Bone: stiffness0.20.40.8-0.4-0.9-0.5-0.40.7-0.4-0.8-0.3-0.0-0.7-0.80.8-0.6
Bone: tissue strength0.50.51.70.90.20.51.0-0.30.90.21.01.30.60.20.60.5
Bone: trabecular number0.00.10.30.00.20.30.0-0.30.20.3-0.1-0.50.20.30.00.2
Bone: trabecular spacing0.50.62.10.90.40.41.2-0.60.80.51.11.50.70.5-0.20.5
Bone: trabecular thickness0.00.00.1-0.00.20.1-0.1-0.10.10.1-0.1-0.30.10.1-0.00.1
Bone: trabecular tissue density1.11.62.51.61.11.41.4-1.01.40.91.51.21.30.9-0.61.5
Breakpoint value in progressive ratio session0.10.10.4-0.0-0.3-0.6-0.00.4-0.2-0.40.10.6-0.3-0.40.4-0.4
Distance traveled before self-admin0.40.51.00.60.70.60.7-0.90.60.60.70.50.80.6-1.00.6
Distance traveled after self-admin1.21.32.31.41.01.30.9-1.31.00.91.20.51.30.9-1.21.5
Delta time in closed arm before/after self-admin0.20.20.4-0.6-0.3-0.4-0.50.6-0.5-0.1-0.7-0.6-0.5-0.10.4-0.5
Delta time in open arm before/after self-admin0.30.31.50.6-0.4-0.00.50.40.2-0.60.71.2-0.0-0.60.80.1
Diff in mean of infusions in LGA sessions0.70.71.30.61.01.00.6-1.10.71.00.5-0.11.01.0-1.10.9
Extinction: sum of active levers before priming0.50.50.7-0.9-0.6-0.8-0.70.6-0.8-0.5-0.8-0.5-0.7-0.50.5-0.8
Active lever presses in extinction session 61.31.32.7-0.8-1.0-1.6-0.61.3-1.0-1.3-0.50.6-1.3-1.31.3-1.4
Delta distance traveled before/after self-admin1.21.32.71.60.81.51.0-0.91.20.81.40.61.20.8-0.11.6
Delta ambulatory time before/after self-admin0.40.41.21.10.31.00.5-0.30.70.30.80.30.60.30.21.1
Time in closed arm before self-admin0.40.51.0-1.0-0.3-0.9-0.80.5-0.8-0.6-0.9-0.6-0.8-0.6-0.0-0.9
Time in closed arm after self-admin1.21.32.6-1.6-0.5-1.3-1.40.9-1.4-0.5-1.6-1.3-1.2-0.50.1-1.3
Time in open arm before self-admin0.91.02.01.40.61.01.1-0.81.00.81.31.01.00.80.11.2
Time in open arm after self-admin1.82.04.52.10.61.11.7-1.01.50.72.12.11.30.70.01.5
Sum of active levers in priming session hrs 5-60.70.61.6-1.20.1-0.8-0.90.4-0.9-0.0-1.2-1.3-0.7-0.0-0.4-0.8
Time to tail flick, vehicle, before self-admin3.43.56.2-1.5-2.1-2.4-1.11.9-1.8-2.0-1.10.4-2.0-2.02.5-2.2
Time to tail flick, vehicle, after self-admin0.40.41.1-0.40.90.40.0-0.90.30.9-0.3-0.70.50.9-1.10.1
Time to tail flick, test, before self-admin0.20.20.6-0.40.70.00.1-0.3-0.00.6-0.3-0.50.10.6-0.3-0.1
Time to tail flick, test, after self-admin4.95.06.7-2.6-2.2-2.4-2.32.2-2.3-2.1-2.4-1.5-2.4-2.12.0-2.6
Delta time to tail flick, vehicle, before/after SA1.01.03.3-0.11.21.20.1-1.10.61.1-0.3-1.20.91.1-1.80.7
Delta time to tail flick, test, before/after SA2.82.53.6-1.5-1.9-1.6-1.61.6-1.5-1.7-1.4-0.8-1.7-1.71.5-1.7
Ambulatory time before self-admin0.30.30.40.50.40.40.6-0.70.50.40.60.70.60.4-0.60.4
Ambulatory time after self-admin1.11.22.21.40.91.40.9-1.21.00.81.10.41.20.8-1.01.5
Total heroin consumption2.53.04.1-1.8-1.6-2.0-1.91.7-1.9-1.7-1.8-1.2-1.9-1.71.2-1.9
Area under the delay curve1.81.93.11.11.41.80.8-1.51.51.40.9-0.21.51.4-1.71.6
Delay disc. indifference point, 0s delay1.31.42.01.31.01.31.2-1.11.41.01.31.01.31.0-1.11.3
Delay disc. indifference point, 16s delay0.90.92.80.41.01.20.1-1.10.71.00.1-1.00.91.0-1.71.0
Delay disc. indifference point, 2s delay1.61.73.11.51.11.61.3-1.01.81.01.51.11.51.0-0.81.5
Delay disc. indifference point, 24s delay1.91.96.20.11.51.5-0.0-1.60.71.5-0.2-1.71.21.5-2.51.1
Delay disc. indifference point, 4s delay0.90.91.91.00.81.21.0-0.81.40.81.00.61.10.8-0.71.0
Delay disc. indifference point, 8s delay0.80.82.00.51.01.10.1-0.90.81.00.2-0.70.91.0-1.41.0
Delay discount exponential model param1.81.93.5-1.0-1.5-1.7-0.71.5-1.5-1.5-0.80.3-1.5-1.51.9-1.5
Delay discount hyperbolic model param1.61.72.9-1.1-1.4-1.7-0.81.4-1.5-1.4-0.90.1-1.5-1.41.6-1.5
Fecal boli incidents, locomotor time 11.82.03.2-1.8-1.3-1.2-1.81.2-1.4-1.2-1.8-1.7-1.4-1.20.1-1.5
Change in fecal boli incidents, locomotor task0.10.10.30.30.40.10.3-0.10.10.20.30.20.10.20.50.3
Time >=10cm from walls, locomotor time 10.20.20.8-0.5-0.1-0.2-0.40.2-0.3-0.2-0.5-0.6-0.3-0.20.9-0.3
Bouts of movement, locomotor time 10.70.82.7-1.3-0.3-0.4-1.10.3-0.8-0.4-1.3-1.7-0.6-0.4-0.9-0.7
Total resting periods, locomotor time 11.11.23.9-1.6-0.4-0.6-1.40.4-1.1-0.5-1.7-2.0-0.7-0.5-0.9-1.0
Rest time, locomotor task time 11.01.11.9-1.4-0.7-0.7-1.00.9-1.2-1.0-1.4-1.3-0.9-1.0-0.2-1.1
Distance moved, locomotor task time 14.14.47.11.72.42.11.5-2.52.12.71.50.32.22.7-2.22.2
Vertical activity count, locomotor time 10.80.81.41.10.60.91.0-0.81.20.71.21.00.90.70.31.0
Time >=10cm from walls, locomotor time 20.30.41.30.3-0.5-0.40.30.70.1-0.60.51.2-0.3-0.61.1-0.3
Bouts of movement, locomotor time 20.20.20.40.60.20.20.3-0.50.50.10.60.60.30.1-0.60.3
Total resting periods, locomotor time 20.10.10.30.4-0.1-0.10.1-0.20.2-0.10.40.60.1-0.1-0.20.1
Rest time, locomotor task time 20.10.10.3-0.6-0.1-0.4-0.40.0-0.4-0.2-0.5-0.4-0.3-0.2-0.0-0.5
Distance moved, locomotor task time 20.91.13.20.61.21.20.6-1.10.81.20.4-0.41.01.2-1.81.1
Vertical activity count, locomotor time 20.40.50.80.80.50.90.7-0.50.80.50.70.40.80.5-0.50.9
Weight adjusted by age0.91.01.5-1.0-1.1-0.9-0.91.1-1.0-1.2-0.9-0.4-1.0-1.21.2-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.1-0.2-0.50.10.2-0.2-0.1-0.00.4-0.3-0.10.0-0.3
Locomotion in novel chamber2.22.73.7-1.7-1.4-1.6-1.91.6-1.8-1.6-1.8-1.5-1.8-1.61.5-1.7
Locomotion in novel chamber post-restriction0.60.72.5-0.9-0.7-0.4-1.20.6-0.8-0.6-1.2-1.6-0.7-0.6-0.1-0.5
Progressive ratio1.31.52.7-1.4-0.9-1.1-1.50.9-1.5-1.1-1.6-1.6-1.2-1.10.1-1.2
Food seeking constrained by brief footshock1.92.35.91.01.91.50.9-1.61.01.80.7-0.51.51.8-2.41.6
Seeking ratio, punishment vs. effort3.23.95.22.31.81.92.2-1.82.11.92.31.82.11.9-1.32.1
Run reversals in cocaine runway, females0.60.62.60.9-0.4-0.10.70.50.4-0.51.01.60.0-0.51.50.1
Run reversals in cocaine runway, males2.92.84.22.01.41.52.0-1.42.01.52.11.91.71.5-0.41.7
Latency to leave start box in cocaine runway1.31.42.2-1.2-1.0-1.5-1.40.9-1.5-1.2-1.2-0.9-1.4-1.20.7-1.3
Latency to leave start box in cocaine runway, F1.61.82.6-1.3-1.3-1.6-1.31.2-1.4-1.4-1.2-0.5-1.5-1.41.3-1.6
Latency to leave start box in cocaine runway, M0.20.20.70.30.70.1-0.1-0.6-0.00.50.1-0.40.20.5-0.80.5
Cd content in liver0.30.40.90.70.40.90.9-0.10.70.10.70.70.60.10.50.6
Co content in liver0.40.51.10.31.00.80.2-0.80.60.80.1-0.60.70.8-1.00.7
Cu content in liver0.20.20.7-0.7-0.0-0.3-0.70.1-0.5-0.1-0.7-0.8-0.3-0.1-0.5-0.5
Fe content in liver0.20.21.20.1-0.8-0.20.00.4-0.0-0.40.20.6-0.3-0.41.1-0.2
K content in liver4.14.19.91.52.12.21.2-2.41.82.41.2-0.32.12.4-3.22.2
Mg content in liver1.71.83.51.31.11.51.0-1.41.31.41.10.31.41.4-1.91.5
Mn content in liver0.91.12.2-1.2-0.9-1.0-1.50.6-1.1-0.7-1.4-1.5-1.0-0.7-0.2-1.0
Na content in liver3.73.95.22.21.82.01.7-2.12.12.02.01.12.12.0-2.02.3
Rb content in liver0.70.91.90.81.11.40.8-0.90.90.90.70.11.10.9-0.81.1
Se content in liver1.11.41.81.01.21.21.2-1.31.31.31.00.51.31.3-1.01.2
Sr content in liver0.60.50.8-0.9-0.6-0.7-0.90.6-0.8-0.6-0.9-0.9-0.7-0.60.3-0.7
Zn content in liver0.20.20.40.50.30.60.4-0.50.50.50.4-0.00.50.5-0.10.6