Hub : Genes

Apip

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007446 0.08 0.07 5.5e-09 0.07 0.07 0.06 0.07 9.4e-09 2.2e-08 1.1e-07 5.3e-08
2 BLA gene expression ENSRNOG00000007446 0.41 0.2 0.0e+00 0.35 0.36 0.36 0.37 9.3e-20 1.6e-20 2.8e-20 1.3e-20
3 BLA mRNA stability ENSRNOG00000007446 0.51 0.19 0.0e+00 0.38 0.41 0.39 0.4 1.4e-21 8.6e-24 2.1e-22 6.8e-23
4 Brain gene expression ENSRNOG00000007446 0.16 0.08 0.0e+00 0.24 0.2 0.24 0.23 1.0e-21 3.2e-18 5.6e-22 8.6e-21
5 Brain mRNA stability ENSRNOG00000007446 0.3 0.15 0.0e+00 0.34 0.32 0.35 0.35 1.0e-32 4.6e-30 4.1e-34 9.1e-34
6 IL gene expression ENSRNOG00000007446 0.42 0.22 5.5e-10 0.29 0.38 0.3 0.35 8.8e-08 4.8e-10 7.9e-08 3.2e-09
7 IL intron excision ratio chr3:89432141:89449197 0.15 0.13 1.5e-03 0.21 0.1 0.17 0.2 7.1e-06 1.9e-03 5.7e-05 1.3e-05
8 IL mRNA stability ENSRNOG00000007446 0.49 0.2 1.6e-11 0.28 0.33 0.31 0.3 1.8e-07 1.1e-08 3.5e-08 7.1e-08
9 LHb gene expression ENSRNOG00000007446 0.18 0.14 6.6e-04 0.06 0.07 0.01 0.05 1.9e-02 1.2e-02 2.0e-01 2.9e-02
10 LHb mRNA stability ENSRNOG00000007446 0.47 0.34 1.9e-06 0.21 0.23 0.25 0.24 1.0e-05 4.2e-06 1.5e-06 2.4e-06
11 NAcc gene expression ENSRNOG00000007446 0.45 0.2 0.0e+00 0.4 0.43 0.43 0.42 4.5e-32 5.3e-35 2.4e-34 6.2e-34
12 NAcc mRNA stability ENSRNOG00000007446 0.32 0.18 0.0e+00 0.3 0.3 0.33 0.31 6.1e-23 8.3e-23 7.1e-25 3.7e-23
13 OFC gene expression ENSRNOG00000007446 0.52 0.27 5.6e-09 0.23 0.3 0.27 0.27 3.4e-06 9.7e-08 3.5e-07 4.6e-07
14 OFC mRNA stability ENSRNOG00000007446 0.5 0.21 1.4e-11 0.34 0.37 0.35 0.37 7.3e-09 9.2e-10 3.9e-09 8.9e-10
15 PL gene expression ENSRNOG00000007446 0.47 0.21 0.0e+00 0.42 0.41 0.4 0.39 6.3e-34 7.2e-33 1.6e-32 9.4e-32
16 PL mRNA stability ENSRNOG00000007446 0.39 0.21 0.0e+00 0.36 0.37 0.36 0.23 5.2e-28 2.7e-29 1.4e-28 2.8e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
BMI with tail0.20.61.0-1.00.70.70.60.90.70.70.70.70.80.80.30.80.81.00.7
BMI without tail0.51.11.3-1.11.11.01.01.11.00.91.01.00.91.10.91.11.01.11.0
Body weight0.52.33.7-1.91.01.41.51.71.41.61.41.41.71.50.91.41.61.91.4
Epididymis fat weight0.81.92.3-1.31.41.41.41.31.41.51.41.41.51.31.01.31.51.31.4
Glucose2.13.23.7-1.71.91.81.71.71.81.81.81.81.81.81.91.81.81.61.8
Heart weight0.60.91.60.8-0.9-0.9-0.8-0.8-0.9-1.0-0.8-0.9-1.3-1.1-1.0-1.1-1.0-0.8-0.9
Left kidney weight0.61.82.8-1.51.01.21.31.41.21.51.21.21.71.31.11.31.41.61.2
Right kidney weight0.61.83.0-1.41.21.21.21.51.21.41.11.21.71.41.11.41.41.61.2
Tail length0.31.01.3-1.11.01.01.01.11.01.01.01.01.01.00.91.01.01.11.0
Length with tail0.31.01.7-1.30.30.91.11.11.01.11.01.01.20.80.50.81.01.30.9
Length without tail0.20.40.8-0.9-0.00.50.60.60.60.80.60.50.90.50.20.40.60.80.5
Liver weight, left0.10.20.4-0.40.60.50.50.40.50.40.50.50.30.40.50.40.40.40.5
Liver weight, right1.01.72.2-1.31.11.31.21.31.31.51.31.31.51.31.31.31.41.31.3
Parametrial fat weight1.02.03.0-1.51.71.41.31.51.31.31.31.41.41.41.71.51.41.31.4
Retroperitoneal fat weight8.829.130.7-5.55.25.45.55.55.55.45.55.45.55.35.15.25.45.55.4
Intraocular pressure0.00.00.20.10.30.1-0.00.00.10.10.10.1-0.00.10.40.10.1-0.00.1
Extensor digitorum longus weight0.41.52.41.2-1.4-1.2-1.2-1.2-1.2-1.1-1.2-1.2-1.2-1.2-1.6-1.2-1.2-1.2-1.2
Soleus weight1.54.35.12.0-2.3-2.2-2.1-2.1-2.2-1.9-2.2-2.2-1.8-2.1-2.2-2.0-2.0-2.0-2.2
Tibialis anterior weight3.211.111.93.3-3.4-3.3-3.3-3.3-3.3-3.2-3.3-3.3-3.4-3.4-3.4-3.4-3.4-3.2-3.3
Tibia length0.20.60.80.6-0.8-0.7-0.7-0.7-0.7-0.8-0.7-0.7-0.9-0.8-0.9-0.8-0.8-0.6-0.7
Number of licking bursts0.10.10.3-0.3-0.00.40.50.30.40.50.40.40.40.30.10.20.40.40.4
Food consumed during 24 hour testing period7.08.59.2-2.92.92.92.82.92.92.82.92.92.92.93.02.92.92.92.9
Times rat made contact with spout0.10.10.2-0.30.40.40.40.40.40.40.40.40.40.40.40.40.40.40.4
Mean time between licks in bursts1.11.52.31.1-1.5-1.2-1.2-1.2-1.2-1.1-1.2-1.2-1.2-1.3-1.5-1.3-1.2-1.1-1.2
Mean num. licks in bursts0.00.00.2-0.20.50.1-0.00.20.1-0.00.00.10.10.20.40.30.10.10.1
Std. dev. time between licks in bursts0.80.91.30.9-1.0-0.9-0.8-1.0-0.9-0.9-0.8-0.9-1.2-1.1-1.1-1.1-1.0-1.0-0.9
Water consumed over 24 hours0.10.10.2-0.30.00.30.30.30.30.40.30.30.30.30.10.20.30.40.3
Indifference point 0 sec0.20.30.60.5-0.6-0.5-0.6-0.5-0.5-0.6-0.5-0.5-0.7-0.5-0.5-0.5-0.5-0.4-0.5
Indifference point AUC1.21.42.01.3-0.7-1.2-1.4-1.3-1.2-1.3-1.3-1.2-1.1-1.1-0.7-1.0-1.2-1.4-1.2
Indifference point function ln k0.60.91.4-1.10.20.91.11.01.01.21.00.91.00.80.30.71.01.20.9
Indifference point function log k0.60.91.4-1.10.20.91.11.01.01.21.00.91.00.80.30.71.01.20.9
Delay discounting total patch changes 0 sec0.10.20.40.4-0.5-0.4-0.5-0.4-0.4-0.5-0.4-0.4-0.6-0.4-0.4-0.4-0.4-0.3-0.4
Delay discounting total patch changes 12 sec0.20.20.8-0.40.80.40.20.50.40.30.40.40.20.50.90.60.40.40.4
Delay discounting total patch changes 18 sec0.40.50.70.8-0.6-0.7-0.8-0.8-0.7-0.6-0.7-0.7-0.5-0.7-0.5-0.6-0.6-0.9-0.7
Delay discounting total patch changes 24 sec1.01.21.51.1-0.9-1.1-1.2-1.0-1.2-1.2-1.2-1.1-1.2-1.1-0.9-1.1-1.1-1.1-1.1
Delay discounting total patch changes 6 sec0.20.20.60.6-0.0-0.4-0.5-0.5-0.5-0.7-0.5-0.5-0.8-0.40.0-0.3-0.5-0.6-0.5
Delay discounting time to switch 0 sec0.00.00.10.00.40.0-0.00.00.0-0.2-0.00.0-0.20.10.30.1-0.1-0.10.0
Delay discounting water rate 0 sec0.00.00.3-0.0-0.6-0.1-0.1-0.1-0.10.1-0.1-0.10.1-0.2-0.4-0.2-0.00.0-0.1
Delay discounting water rate 12 sec0.40.51.40.5-1.2-0.7-0.5-0.6-0.6-0.6-0.6-0.7-0.4-0.8-1.1-0.9-0.6-0.5-0.7
Delay discounting water rate 18 sec0.60.81.3-1.10.50.90.91.00.91.00.90.91.00.80.50.70.91.10.9
Delay discounting water rate 24 sec0.30.41.00.6-1.0-0.6-0.5-0.6-0.5-0.5-0.5-0.6-0.5-0.8-1.0-0.9-0.6-0.5-0.6
Delay discounting water rate 6 sec0.10.10.8-0.0-0.7-0.2-0.1-0.1-0.20.0-0.2-0.20.2-0.4-0.9-0.4-0.10.0-0.2
Locomotor activity0.00.00.10.00.20.10.20.10.20.10.20.1-0.20.00.10.00.10.10.1
Locomotor testing distance0.91.51.7-1.21.31.31.31.31.31.11.31.30.91.21.11.11.21.21.3
Locomotor testing rearing0.00.10.1-0.30.30.30.40.30.30.20.30.30.10.20.10.20.30.30.3
Light reinforcement 10.30.51.4-0.90.70.60.60.70.60.40.50.60.40.71.20.70.60.70.6
Light reinforcement 20.00.10.2-0.40.00.10.10.20.10.10.10.10.10.20.40.20.10.40.1
Reaction time number correct0.00.00.20.00.30.0-0.10.00.0-0.30.00.0-0.3-0.10.5-0.1-0.1-0.10.0
Reaction time mean minus median0.50.61.6-0.71.30.80.60.80.70.70.70.70.70.90.70.90.80.60.8
Reaction time mean minus median AUC0.30.41.0-0.61.00.70.50.70.60.60.60.60.60.70.50.80.70.50.6
Reaction time num false alarms1.52.02.81.5-1.4-1.4-1.4-1.4-1.4-1.3-1.4-1.4-1.5-1.4-1.7-1.4-1.4-1.4-1.4
Reaction time num false alarms AUC2.33.34.51.9-1.8-1.8-1.8-1.8-1.7-1.6-1.7-1.8-1.9-1.8-2.1-1.8-1.8-1.8-1.8
Reaction time trials correct on left0.00.00.20.00.30.0-0.10.00.0-0.30.00.0-0.3-0.10.5-0.1-0.1-0.10.0
Reaction time trials on left0.00.00.20.10.2-0.1-0.2-0.1-0.1-0.4-0.1-0.1-0.4-0.20.4-0.2-0.2-0.2-0.1
Reaction time mean0.20.30.5-0.50.70.60.50.60.60.60.50.60.70.60.30.60.60.50.6
Reaction time mean AUC0.30.40.6-0.60.70.70.70.70.70.70.70.70.80.70.30.70.70.60.7
Median of all reaction times0.40.50.8-0.70.70.70.70.70.70.80.70.70.90.80.40.80.70.70.7
Reaction time omissions0.81.01.31.1-0.8-1.1-1.1-1.0-1.1-1.0-1.1-1.1-1.0-1.0-1.1-0.9-1.0-1.0-1.1
Reaction time false alarm rate2.63.75.92.0-2.0-1.9-1.9-1.9-1.9-1.6-1.9-1.9-1.8-1.9-2.4-1.9-1.9-1.9-1.9
Reaction time premature initiation rate0.20.30.50.5-0.4-0.5-0.5-0.5-0.5-0.6-0.5-0.5-0.7-0.6-0.5-0.6-0.6-0.5-0.5
Reaction time premature initiations0.20.20.60.4-0.1-0.4-0.5-0.4-0.4-0.7-0.4-0.5-0.8-0.5-0.1-0.5-0.5-0.4-0.4
Std. dev. reaction times0.00.10.2-0.10.50.20.10.20.20.20.20.20.20.3-0.00.30.20.10.2
Reaction time trials completed0.00.00.20.10.2-0.1-0.2-0.1-0.1-0.4-0.1-0.1-0.4-0.20.4-0.2-0.2-0.2-0.1
Reaction time trials AUC0.00.00.4-0.10.50.10.10.10.1-0.20.10.1-0.10.10.60.10.10.00.1
Social response proportion4.85.26.42.2-2.2-2.3-2.3-2.2-2.3-2.3-2.3-2.3-2.5-2.2-2.2-2.2-2.3-2.2-2.3
Social responses0.10.10.2-0.40.40.30.30.40.30.30.30.30.20.30.40.30.30.50.3
Social time2.33.04.81.9-1.2-1.7-1.8-1.7-1.7-2.0-1.7-1.7-2.2-1.6-1.1-1.6-1.8-1.9-1.7
Conditioned locomotion4.55.36.92.2-2.6-2.3-2.1-2.3-2.3-2.1-2.2-2.3-2.3-2.4-2.6-2.4-2.3-2.2-2.3
Cocaine response after cond. corrected2.12.42.71.6-1.4-1.6-1.7-1.6-1.6-1.5-1.6-1.6-1.4-1.5-1.5-1.4-1.5-1.6-1.6
Cocaine response after cond. not corrected0.50.50.60.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Cocaine response before conditioning4.55.46.2-2.42.22.42.52.42.42.32.52.42.22.22.32.12.32.42.4
Saline control response0.71.01.3-1.11.11.01.11.11.00.81.01.00.70.91.10.90.91.11.0
Condit. Reinf. active minus inactive responses1.01.31.5-1.11.21.21.21.21.21.01.21.20.91.11.21.01.11.11.2
Condit. Reinf. active-inactive response ratio2.83.03.6-1.71.61.81.91.81.91.61.91.81.51.71.51.61.71.71.8
Condit. Reinf. active responses0.71.01.2-1.00.91.01.01.01.11.01.11.00.91.00.80.91.01.01.1
Condit. Reinf. inactive responses0.00.00.1-0.0-0.3-0.1-0.1-0.0-0.10.1-0.1-0.10.2-0.0-0.4-0.00.00.1-0.1
Condit. Reinf. lever presses0.40.60.8-0.80.80.80.80.80.90.60.90.90.60.80.70.70.70.80.9
Condit. Reinf. lever reinforcers received0.81.11.2-1.01.01.11.01.11.11.01.11.10.91.00.91.01.01.11.1
Pavlov. Cond. lever latency2.12.83.51.6-1.9-1.7-1.7-1.7-1.8-1.4-1.8-1.8-1.4-1.7-1.8-1.7-1.6-1.6-1.8
Pavlov. Cond. magazine entry latency1.01.11.3-1.10.91.11.01.21.11.01.11.11.01.10.71.11.11.11.1
Pavlov. Cond. change in total contacts0.91.21.5-1.11.11.21.11.11.20.91.21.20.91.11.11.11.11.11.2
Pavlov. Cond. index score1.82.42.7-1.51.51.61.51.61.61.41.61.61.41.61.41.51.51.61.6
Pavlov. Cond. latency score2.32.93.3-1.71.61.81.71.81.81.61.81.81.61.71.51.71.71.71.8
Pavlov. Cond. lever contacts2.23.13.6-1.71.91.81.81.81.91.61.91.81.51.71.81.71.71.71.9
Pavlov. Cond. magazine entry number0.50.60.70.8-0.7-0.8-0.7-0.9-0.8-0.7-0.8-0.8-0.7-0.9-0.5-0.9-0.8-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.30.50.0-0.3-0.2-0.4-0.3-0.2-0.3-0.3-0.3-0.30.2-0.3-0.3-0.5-0.3
Pavlov. Cond. lever-magazine prob. diff.1.51.92.2-1.41.31.51.41.51.51.21.51.51.21.41.21.41.41.41.5
Pavlov. Cond. response bias1.72.32.6-1.51.61.61.51.61.61.31.61.61.31.51.51.51.51.51.6
Conditioned reinforcement - actives3.73.74.1-1.82.01.91.81.91.91.91.91.92.02.01.92.01.91.81.9
Conditioned reinforcement - inactives9.510.711.8-3.23.43.33.23.23.33.03.33.33.43.33.33.33.23.13.3
Conditioned locomotion3.03.65.2-1.81.71.81.71.91.82.11.81.82.31.91.72.02.02.01.8
Intermittent access intake day 1-15 change0.10.10.2-0.40.20.30.40.30.30.40.30.30.30.20.20.20.30.30.3
Intermittent access intake escalation0.30.30.4-0.60.50.60.60.60.60.60.60.60.60.50.50.50.60.70.6
Intermittent access intake escalation 22.42.42.7-1.51.31.61.61.51.61.71.61.61.61.51.31.41.61.61.6
Intermitt. access day 1 inactive lever presses0.10.10.30.0-0.5-0.2-0.1-0.1-0.2-0.2-0.2-0.2-0.1-0.2-0.5-0.3-0.10.0-0.2
Intermitt. access day 15 inactive lever presses3.74.15.5-2.01.82.01.92.01.92.11.92.02.32.02.12.12.12.11.9
Intermitt. access escalation Index0.00.00.1-0.00.10.20.30.10.2-0.10.30.2-0.20.0-0.2-0.0-0.00.00.2
Intermittent access day 1 total infusions4.14.65.8-2.12.12.12.02.22.12.22.12.12.42.22.02.22.22.22.1
Intermittent access day 15 total infusions5.05.66.5-2.42.22.42.32.42.42.52.42.42.52.42.22.42.42.42.4
Intermittent access terminal intake (last 3 days)6.67.27.9-2.72.52.72.62.72.72.82.72.72.82.72.52.72.72.72.7
Intermittent access total infusions6.57.17.9-2.72.52.72.62.72.72.72.72.72.82.72.42.72.72.72.7
Intermittent access day 1 locomotion1.81.92.7-1.41.21.31.21.41.31.51.31.31.61.41.21.41.41.51.3
Intermittent access day 15 total locomotion2.72.94.2-1.71.61.71.51.71.61.91.61.72.01.81.41.81.81.81.7
Intermittent access total locomotion3.13.44.4-1.81.71.81.61.91.82.01.81.82.11.91.61.91.92.01.8
Intermittent access standard deviation6.87.28.9-2.82.42.62.52.72.62.92.62.63.02.72.62.72.82.82.6
Cocaine induced anxiety0.30.30.5-0.60.30.50.60.60.50.50.50.50.70.50.50.50.50.60.5
Post-drug Anxiety0.00.00.00.00.00.00.10.00.00.20.00.00.20.10.20.10.1-0.00.0
Baseline Anxiety2.42.52.81.7-1.4-1.6-1.6-1.6-1.6-1.4-1.6-1.6-1.6-1.6-1.6-1.5-1.5-1.7-1.6
Lifetime Intake6.87.68.4-2.72.52.82.72.72.82.82.82.82.92.82.52.72.82.82.8
Incentive Sensitization - Responses1.61.62.4-1.21.51.31.11.21.21.11.21.31.11.41.51.41.21.11.3
Incentive Sensitization - Breakpoint1.41.42.1-1.11.41.21.01.11.21.01.11.21.01.31.41.31.11.01.2
Progressive ratio test 1 active lever presses4.34.45.3-2.22.02.12.02.22.12.12.12.12.32.12.02.12.12.22.1
Progressive ratio test 1 breakpoint3.94.04.9-2.11.92.01.92.02.02.01.92.02.22.01.92.02.02.12.0
Progressive ratio test 1 inactive lever presses2.42.63.4-1.71.51.61.51.61.51.61.51.61.81.61.61.61.61.71.6
Progressive ratio test 2 active lever presses3.43.64.2-1.81.91.91.71.91.91.91.81.92.02.02.02.01.91.91.9
Progressive ratio test 2 breakpoint4.04.45.2-2.02.12.12.02.12.12.12.12.12.22.22.32.22.02.02.1
Progressive ratio test 2 inactive lever presses4.35.06.4-2.22.02.22.12.22.22.32.22.22.52.32.22.32.22.32.2
Total sessions with >9 infusions1.92.12.5-1.51.11.41.51.41.51.61.51.51.61.41.41.41.51.51.5
Short access day 1 total inactive lever presses0.70.80.9-0.90.90.90.90.90.90.91.00.90.80.90.70.80.90.80.9
Short access day 10 total inactive lever presses0.20.20.4-0.40.50.50.50.50.40.40.40.40.50.50.60.50.50.60.4
Short access day 1 total infusions7.98.49.4-2.92.62.92.92.83.03.13.03.03.12.92.82.82.92.83.0
Short access day 10 total infusions3.84.24.9-2.11.82.02.02.12.12.22.12.12.22.01.72.02.12.12.1
Short access total infusions4.95.46.3-2.32.12.42.32.32.42.52.42.42.52.32.12.22.42.32.4
Short access day 1 locomotion3.23.34.5-1.91.41.91.91.81.92.11.91.92.11.71.41.71.91.91.9
Short access day 10 total locomotion4.24.65.6-2.11.92.11.92.22.12.32.12.12.42.22.22.22.22.32.1
Short access total locomotion3.53.64.5-1.91.51.91.81.91.92.11.91.92.11.91.61.82.02.01.9
Compulsive drug intake1.41.41.71.2-0.9-1.2-1.3-1.2-1.2-1.2-1.3-1.2-1.2-1.1-0.8-1.1-1.2-1.2-1.2
One hour access (0.3 mA shock)4.65.47.0-2.32.32.32.12.32.22.42.22.32.62.42.32.52.42.32.2
One hour access (shock baseline)6.98.08.9-2.82.72.82.82.92.82.82.82.83.02.92.62.82.92.92.8
Number of responses in last shaping day1.41.41.9-1.21.11.21.11.11.21.31.21.21.21.21.41.11.11.11.2
Context. condit. distance diff. score2.53.05.3-1.61.81.71.91.61.71.81.71.71.81.52.31.51.71.61.7
Locomotion velocity, session 10.00.00.20.20.2-0.1-0.1-0.0-0.1-0.4-0.1-0.1-0.4-0.10.1-0.1-0.2-0.1-0.1
Locomotion distance, session 10.10.10.2-0.20.40.20.30.30.2-0.00.20.2-0.10.30.40.30.10.20.2
Locomotion velocity, session 20.00.00.10.2-0.0-0.10.0-0.2-0.1-0.2-0.1-0.1-0.3-0.20.1-0.2-0.2-0.2-0.1
Locomotion distance, session 20.30.50.6-0.70.60.70.70.80.70.60.60.70.70.80.30.80.70.70.7
Locomotion velocity, session 30.20.20.6-0.40.70.40.40.40.40.40.40.40.50.50.70.50.40.20.4
Locomotion distance, session 30.30.30.4-0.50.60.50.50.50.50.50.50.50.60.60.60.60.60.50.5
Stereotopy head waving bouts, day 30.00.00.20.20.50.1-0.1-0.00.00.1-0.00.10.20.20.40.20.1-0.10.0
Stereotopy head waving duration, day 30.40.51.0-0.51.00.70.60.60.70.70.70.70.70.70.90.70.70.50.7
Locomotion velocity, session 70.20.20.7-0.10.70.40.30.30.30.30.30.30.40.50.90.50.40.20.3
Locomotion distance, session 70.20.30.40.6-0.5-0.6-0.6-0.5-0.6-0.6-0.6-0.6-0.5-0.5-0.2-0.5-0.5-0.5-0.6
Stereotopy head waving bouts, day 70.00.00.1-0.00.30.10.30.10.10.30.20.10.30.10.30.10.20.00.1
Stereotopy head waving duration, day 70.00.00.00.10.10.00.2-0.00.00.10.10.00.0-0.0-0.1-0.00.1-0.10.0
Locomotion velocity, session 80.70.91.9-0.91.10.90.90.90.80.80.80.90.90.91.41.00.90.90.9
Locomotion distance, session 83.24.76.4-2.12.22.12.22.22.12.22.12.12.22.12.52.12.22.12.1
Degree of sensitization distance0.50.50.70.7-0.8-0.8-0.7-0.7-0.7-0.7-0.7-0.8-0.8-0.8-0.4-0.8-0.7-0.6-0.8
Degree of sensitization stereotypy0.00.00.00.1-0.0-0.10.1-0.1-0.10.0-0.1-0.1-0.0-0.2-0.0-0.2-0.0-0.1-0.1
Condit. Reinf. active minus inactive responses1.01.11.4-0.90.91.11.10.91.11.21.21.11.21.01.10.91.10.91.1
Condit. Reinf. active-inactive response ratio2.02.22.9-1.41.11.51.71.41.61.71.61.51.71.31.11.31.51.41.5
Condit. Reinf. active responses0.30.30.5-0.40.40.60.70.50.70.70.70.60.70.50.50.50.60.40.6
Condit. Reinf. inactive responses0.40.40.60.7-0.6-0.6-0.8-0.7-0.7-0.7-0.7-0.6-0.7-0.6-0.7-0.6-0.7-0.7-0.6
Incentive salience index mean0.91.11.4-0.90.81.11.21.01.11.11.21.11.11.00.91.01.11.01.1
Condit. Reinf. lever presses0.71.01.3-1.00.81.01.11.01.11.01.11.10.91.00.70.91.01.01.1
Time in familiar zone, hab. session 10.50.40.60.6-0.4-0.7-0.7-0.7-0.7-0.7-0.8-0.7-0.6-0.7-0.4-0.6-0.7-0.7-0.7
Time in novel zone, hab. session 10.80.81.0-0.90.60.91.00.91.00.91.01.00.80.80.40.80.91.01.0
Total zone transitions, hab. session 12.63.64.4-1.82.01.91.81.91.91.81.91.91.91.92.11.91.91.91.9
Total locomotion distance, hab. session 11.11.62.3-1.11.31.21.21.21.21.41.21.21.51.21.51.31.31.31.2
Locomotion velocity, hab. session 10.81.11.8-1.01.21.01.01.01.01.10.91.01.31.01.31.11.11.01.0
Time in familiar zone, hab. session 20.10.10.3-0.30.20.20.10.20.10.40.10.20.60.3-0.10.30.30.30.2
Time in novel zone, hab. session 20.00.00.20.1-0.1-0.00.1-0.00.0-0.30.1-0.0-0.5-0.10.1-0.2-0.2-0.10.0
Total zone transitions, hab. session 22.12.73.2-1.71.61.61.51.71.61.61.61.61.81.71.51.81.71.71.6
Total locomotion distance, hab. session 20.10.10.3-0.30.30.20.10.30.20.30.10.20.50.30.40.30.30.30.2
Locomotion velocity, hab. session 20.00.10.2-0.30.20.10.00.20.10.30.10.10.50.20.30.30.20.30.1
Novel to familiar place preference ratio1.11.11.5-0.91.01.01.01.01.01.11.01.01.21.11.21.11.11.01.0
Novelty place preference1.01.01.5-0.91.01.00.91.01.01.11.01.01.21.01.21.11.10.91.0
Time in novel zone, NPP test0.70.71.0-0.70.80.80.80.80.80.90.80.80.90.81.00.90.90.70.8
Total zone transitions, NPP test0.50.71.21.0-0.6-0.8-0.8-0.8-0.8-1.0-0.8-0.8-1.1-0.8-0.6-0.8-0.9-0.9-0.8
Total locomotion distance, NPP test0.30.50.60.7-0.5-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.7-0.3-0.7-0.7-0.7-0.7
Locomotion velocity, NPP test0.20.30.40.6-0.4-0.6-0.6-0.5-0.6-0.5-0.6-0.6-0.4-0.5-0.1-0.5-0.5-0.5-0.6
Pavlov. Cond. lever latency0.60.71.20.8-0.9-0.8-0.9-0.8-0.8-0.7-0.8-0.8-0.7-0.9-1.1-0.9-0.8-0.8-0.9
Pavlov. Cond. magazine entry latency1.11.51.7-1.21.31.21.21.21.21.11.21.21.21.31.21.31.21.21.2
Pavlov. Cond. change in total contacts0.10.10.30.2-0.5-0.4-0.3-0.2-0.4-0.4-0.4-0.4-0.4-0.3-0.6-0.3-0.3-0.2-0.4
Pavlov. Cond. index score0.50.60.8-0.80.80.70.70.80.70.60.70.70.80.80.80.90.70.80.7
Pavlov. Cond. latency score0.50.70.9-0.90.80.80.70.90.70.70.70.80.80.90.90.90.80.80.8
Pavlov. Cond. lever contacts0.30.40.5-0.60.60.60.70.60.60.50.60.60.50.60.70.60.60.70.6
Pavlov. Cond. magazine entry number1.11.41.71.2-1.3-1.2-1.1-1.2-1.1-1.1-1.1-1.2-1.2-1.3-1.2-1.3-1.2-1.2-1.2
Pavlov. Cond. intertrial magazine entries0.00.10.10.3-0.2-0.2-0.3-0.3-0.2-0.3-0.1-0.2-0.4-0.3-0.0-0.3-0.2-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.40.40.6-0.70.70.70.70.70.60.50.60.70.60.70.70.80.60.70.6
Pavlov. Cond. response bias0.91.11.3-1.01.11.01.01.01.00.91.01.01.01.11.11.11.01.01.0
Bone: apparent density0.61.01.4-1.20.91.01.11.01.11.01.11.01.01.00.81.01.01.01.1
Bone surface0.50.91.1-1.00.60.91.01.01.01.01.00.91.00.90.50.81.01.00.9
Bone volume1.52.62.8-1.71.41.61.71.61.61.61.71.61.71.61.31.61.71.61.6
Bone: connectivity density0.40.70.9-1.00.70.91.00.80.90.80.90.90.80.80.60.80.90.80.9
Bone: cortical apparent density0.10.10.20.2-0.4-0.3-0.3-0.2-0.3-0.2-0.4-0.3-0.0-0.2-0.4-0.2-0.3-0.2-0.3
Bone: cortical area0.10.10.3-0.4-0.20.20.20.30.30.50.30.20.50.2-0.10.20.40.40.2
Bone: cortical porosity0.50.60.70.8-0.6-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.8-0.8-0.4-0.8-0.8-0.8-0.8
Bone: cortical porosity0.30.30.40.6-0.5-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.3-0.7-0.6-0.6-0.6
Bone: cortical thickness0.00.00.10.0-0.4-0.1-0.2-0.1-0.10.0-0.1-0.10.1-0.1-0.3-0.1-0.0-0.0-0.1
Bone: cortical thickness4.35.16.72.1-2.6-2.3-2.2-2.3-2.2-2.1-2.2-2.3-2.2-2.3-2.5-2.4-2.2-2.1-2.3
Bone: cortical tissue density0.00.00.10.1-0.3-0.2-0.2-0.2-0.2-0.1-0.3-0.20.0-0.1-0.3-0.1-0.2-0.1-0.2
Bone: elastic displacement2.02.22.91.5-1.3-1.5-1.6-1.5-1.5-1.5-1.4-1.5-1.7-1.5-1.4-1.5-1.5-1.5-1.5
Bone: elastic work1.51.92.41.3-1.3-1.4-1.5-1.4-1.4-1.3-1.4-1.4-1.4-1.4-1.3-1.4-1.4-1.4-1.4
Bone: endosteal estimation0.30.61.20.5-1.1-0.7-0.6-0.7-0.7-0.5-0.7-0.7-0.6-0.8-1.1-0.8-0.7-0.6-0.7
Bone: endosteal perimeter0.20.50.8-0.90.30.70.80.70.70.80.70.70.80.60.30.60.70.80.7
Bone: final force0.00.00.00.1-0.2-0.1-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.1-0.1
Bone: final moment0.10.20.20.4-0.5-0.4-0.5-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.3-0.4-0.3-0.4-0.4
Bone: marrow area0.30.61.20.5-1.1-0.7-0.6-0.7-0.7-0.6-0.7-0.7-0.6-0.8-1.1-0.8-0.7-0.6-0.7
Bone: maximum diameter0.10.20.4-0.6-0.00.40.50.40.40.60.40.40.60.30.00.30.50.50.4
Bone: maximum force0.00.00.1-0.3-0.10.20.10.20.20.30.20.20.30.20.00.10.30.30.2
Bone: maximum moment0.00.10.20.1-0.4-0.3-0.3-0.2-0.3-0.1-0.3-0.3-0.1-0.3-0.3-0.3-0.2-0.1-0.3
Bone: minimum diameter0.40.81.2-1.00.30.80.90.90.91.10.90.81.10.70.40.71.01.00.8
Bone: periosteal estimation0.10.20.70.1-0.9-0.4-0.3-0.3-0.3-0.1-0.3-0.4-0.1-0.4-0.8-0.5-0.3-0.2-0.4
Bone: periosteal perimeter1.11.72.7-1.51.01.31.31.31.31.51.31.31.61.31.01.31.41.41.3
Bone: post-yield work0.00.00.10.1-0.3-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.3-0.2-0.1-0.1-0.1
Bone: stiffness0.40.60.9-0.90.40.70.70.80.70.90.70.70.90.70.60.70.80.90.7
Bone: tissue strength0.00.00.00.00.0-0.1-0.2-0.0-0.1-0.0-0.1-0.10.0-0.0-0.00.0-0.0-0.0-0.1
Bone: trabecular number0.40.60.8-0.90.50.80.80.80.80.70.80.80.70.70.50.70.80.80.8
Bone: trabecular spacing0.30.40.8-0.50.90.60.60.60.60.60.60.60.70.70.90.80.60.60.6
Bone: trabecular thickness0.20.20.4-0.60.30.40.40.50.50.50.50.50.50.40.30.40.50.50.5
Bone: trabecular tissue density0.91.31.61.1-1.1-1.2-1.2-1.1-1.2-1.0-1.3-1.2-0.9-1.1-0.9-1.1-1.1-1.1-1.2
Breakpoint value in progressive ratio session1.41.62.41.2-1.1-1.3-1.3-1.3-1.3-1.4-1.3-1.3-1.5-1.2-1.1-1.2-1.3-1.3-1.3
Distance traveled before self-admin0.60.71.0-0.90.60.80.70.90.80.90.80.80.90.90.60.80.91.00.8
Distance traveled after self-admin0.50.60.7-0.70.70.80.70.70.70.70.70.70.80.80.80.80.80.80.7
Delta time in closed arm before/after self-admin0.00.00.1-0.2-0.10.00.10.10.00.1-0.00.00.30.2-0.10.20.10.20.0
Delta time in open arm before/after self-admin0.40.40.90.8-0.7-0.5-0.4-0.7-0.5-0.4-0.5-0.5-0.5-0.6-1.0-0.7-0.6-0.7-0.5
Diff in mean of infusions in LGA sessions0.40.40.70.6-0.7-0.6-0.7-0.7-0.6-0.7-0.6-0.6-0.8-0.6-0.7-0.6-0.7-0.7-0.6
Extinction: sum of active levers before priming0.40.40.6-0.60.60.60.40.70.50.70.40.50.70.70.60.80.70.70.5
Active lever presses in extinction session 60.40.40.7-0.90.80.60.40.70.50.50.50.60.40.70.30.70.60.70.6
Delta distance traveled before/after self-admin0.20.20.40.6-0.3-0.5-0.3-0.5-0.5-0.5-0.5-0.5-0.3-0.5-0.2-0.5-0.4-0.6-0.5
Delta ambulatory time before/after self-admin0.10.10.20.5-0.4-0.4-0.2-0.4-0.4-0.4-0.4-0.4-0.2-0.4-0.1-0.4-0.3-0.4-0.4
Time in closed arm before self-admin0.70.91.3-0.90.91.01.00.81.10.91.11.00.60.81.10.70.80.81.0
Time in closed arm after self-admin0.40.40.5-0.70.40.60.60.60.60.70.70.60.60.50.70.50.60.60.6
Time in open arm before self-admin1.01.01.30.8-0.9-1.1-1.1-0.9-1.1-1.1-1.1-1.1-0.9-1.0-1.2-0.9-1.0-0.9-1.1
Time in open arm after self-admin1.71.92.31.5-1.2-1.3-1.4-1.3-1.4-1.3-1.4-1.4-1.4-1.3-1.5-1.3-1.4-1.3-1.4
Sum of active levers in priming session hrs 5-60.40.40.60.5-0.6-0.7-0.7-0.6-0.7-0.6-0.8-0.7-0.6-0.5-0.5-0.5-0.6-0.5-0.7
Time to tail flick, vehicle, before self-admin5.75.87.1-2.32.52.42.32.42.32.42.32.42.72.52.42.62.42.22.4
Time to tail flick, vehicle, after self-admin5.25.56.4-2.22.52.42.32.32.42.32.42.42.32.42.52.42.32.22.4
Time to tail flick, test, before self-admin0.90.91.3-0.70.81.01.10.81.11.01.11.00.90.91.10.81.00.91.1
Time to tail flick, test, after self-admin2.42.53.1-1.41.51.61.61.41.61.71.61.61.81.51.61.51.71.41.6
Delta time to tail flick, vehicle, before/after SA0.00.00.10.1-0.1-0.0-0.0-0.10.0-0.10.10.0-0.4-0.10.1-0.2-0.1-0.10.0
Delta time to tail flick, test, before/after SA0.10.10.2-0.40.40.30.30.30.30.40.20.30.50.30.20.40.40.30.3
Ambulatory time before self-admin0.30.30.5-0.70.30.50.50.60.50.60.50.50.60.60.10.50.60.70.5
Ambulatory time after self-admin0.50.50.7-0.60.50.70.80.70.70.80.70.70.80.70.50.60.80.80.7
Total heroin consumption0.81.01.30.8-1.1-1.1-1.1-0.9-1.1-0.9-1.1-1.1-0.8-0.9-1.1-0.9-1.0-0.8-1.1
Area under the delay curve0.30.40.50.7-0.7-0.6-0.6-0.6-0.5-0.6-0.5-0.6-0.6-0.6-0.6-0.7-0.6-0.7-0.5
Delay disc. indifference point, 0s delay0.00.00.10.2-0.3-0.1-0.0-0.2-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.2-0.1-0.2-0.1
Delay disc. indifference point, 16s delay2.12.22.41.5-1.4-1.5-1.5-1.5-1.4-1.4-1.4-1.5-1.5-1.5-1.4-1.5-1.5-1.5-1.4
Delay disc. indifference point, 2s delay0.50.60.80.8-0.9-0.7-0.6-0.8-0.7-0.8-0.6-0.7-0.9-0.8-0.9-0.8-0.8-0.8-0.7
Delay disc. indifference point, 24s delay0.40.40.50.7-0.6-0.6-0.6-0.6-0.6-0.5-0.6-0.6-0.5-0.7-0.6-0.7-0.5-0.7-0.6
Delay disc. indifference point, 4s delay0.30.40.70.6-0.8-0.6-0.5-0.6-0.5-0.6-0.5-0.5-0.6-0.6-0.6-0.7-0.6-0.6-0.5
Delay disc. indifference point, 8s delay0.10.10.2-0.30.30.40.40.30.40.40.50.40.40.30.50.30.30.30.4
Delay discount exponential model param0.40.50.7-0.70.80.60.60.70.60.60.60.60.60.70.70.70.70.70.6
Delay discount hyperbolic model param0.30.40.5-0.70.70.60.50.60.50.60.50.60.60.60.60.70.60.70.5
Fecal boli incidents, locomotor time 19.910.712.23.3-3.5-3.3-3.2-3.4-3.2-3.0-3.2-3.3-3.3-3.4-3.3-3.4-3.3-3.3-3.3
Change in fecal boli incidents, locomotor task8.17.79.2-2.72.82.72.62.82.72.62.72.72.82.93.02.92.82.72.7
Time >=10cm from walls, locomotor time 10.20.20.30.5-0.4-0.4-0.4-0.5-0.4-0.3-0.4-0.4-0.3-0.5-0.4-0.5-0.4-0.5-0.4
Bouts of movement, locomotor time 11.31.41.91.2-1.4-1.2-1.2-1.2-1.1-1.2-1.1-1.1-1.2-1.2-1.3-1.3-1.2-1.1-1.1
Total resting periods, locomotor time 11.11.21.71.1-1.3-1.1-1.1-1.1-1.0-1.1-1.0-1.1-1.1-1.1-1.3-1.2-1.1-1.0-1.1
Rest time, locomotor task time 10.70.81.00.9-1.0-0.9-0.9-0.9-0.8-0.9-0.8-0.8-0.8-0.9-1.0-1.0-0.9-0.9-0.8
Distance moved, locomotor task time 12.62.93.9-1.81.61.61.71.71.61.61.61.61.81.72.01.81.71.71.6
Vertical activity count, locomotor time 10.20.20.3-0.40.40.40.50.50.40.50.40.40.40.50.50.50.40.50.4
Time >=10cm from walls, locomotor time 26.06.46.7-2.52.52.62.62.52.62.62.62.62.62.52.42.52.52.52.6
Bouts of movement, locomotor time 20.10.10.20.4-0.2-0.3-0.3-0.2-0.3-0.2-0.3-0.3-0.1-0.3-0.4-0.2-0.2-0.2-0.3
Total resting periods, locomotor time 20.00.00.10.3-0.1-0.2-0.3-0.2-0.3-0.2-0.3-0.2-0.1-0.2-0.3-0.2-0.1-0.1-0.2
Rest time, locomotor task time 22.22.53.61.5-1.6-1.6-1.6-1.6-1.6-1.5-1.6-1.6-1.6-1.6-1.9-1.6-1.6-1.6-1.6
Distance moved, locomotor task time 24.24.95.9-2.32.12.22.32.22.22.02.22.22.22.22.42.22.22.22.2
Vertical activity count, locomotor time 22.72.93.2-1.71.71.71.71.71.71.61.71.71.81.71.81.81.71.71.7
Weight adjusted by age2.32.63.71.6-1.6-1.6-1.7-1.6-1.6-1.7-1.6-1.6-1.9-1.6-1.1-1.6-1.7-1.6-1.6
Seeking ratio, delayed vs. immediate footshock0.20.20.4-0.70.50.50.60.50.50.30.50.50.50.40.50.40.50.50.5
Locomotion in novel chamber0.70.81.0-1.00.70.90.90.90.90.90.90.90.90.91.00.90.90.90.9
Locomotion in novel chamber post-restriction1.51.83.21.3-1.3-1.3-1.2-1.3-1.2-1.2-1.2-1.2-1.4-1.4-1.8-1.4-1.3-1.4-1.2
Progressive ratio0.50.61.2-0.80.70.70.60.80.70.60.70.70.90.81.10.80.80.70.7
Food seeking constrained by brief footshock1.41.72.6-1.41.31.31.21.31.21.21.21.21.31.31.61.41.31.31.2
Seeking ratio, punishment vs. effort0.20.20.40.4-0.4-0.4-0.4-0.4-0.4-0.3-0.4-0.4-0.5-0.5-0.6-0.5-0.4-0.4-0.4
Run reversals in cocaine runway, females0.10.10.2-0.30.00.20.20.30.20.40.20.20.40.30.30.30.30.40.2
Run reversals in cocaine runway, males4.44.25.02.0-1.7-2.1-2.1-2.0-2.1-2.1-2.1-2.1-2.1-2.0-2.2-1.9-2.1-2.0-2.1
Latency to leave start box in cocaine runway0.10.10.10.2-0.4-0.3-0.3-0.3-0.30.0-0.4-0.30.2-0.2-0.4-0.2-0.1-0.2-0.3
Latency to leave start box in cocaine runway, F0.00.00.2-0.10.1-0.0-0.10.1-0.10.2-0.1-0.00.40.20.20.20.10.1-0.0
Latency to leave start box in cocaine runway, M0.30.30.90.5-0.7-0.5-0.4-0.6-0.5-0.3-0.5-0.5-0.2-0.5-0.9-0.5-0.4-0.5-0.5
Cd content in liver1.71.82.9-1.31.71.41.21.31.41.21.31.41.21.41.61.51.31.21.4
Co content in liver1.61.92.41.5-1.2-1.3-1.4-1.4-1.3-1.3-1.3-1.3-1.5-1.4-1.6-1.4-1.4-1.4-1.3
Cu content in liver0.60.81.60.6-1.2-0.9-0.8-0.8-0.8-0.7-0.8-0.8-0.8-0.9-1.3-1.0-0.8-0.7-0.8
Fe content in liver1.01.22.01.4-0.9-1.0-0.9-1.1-1.0-1.2-0.9-1.0-1.4-1.1-1.0-1.1-1.1-1.2-1.0
K content in liver1.71.72.51.4-1.2-1.4-1.6-1.3-1.4-1.3-1.4-1.4-1.1-1.2-1.2-1.2-1.3-1.3-1.4
Mg content in liver2.12.12.41.4-1.5-1.5-1.5-1.4-1.5-1.4-1.5-1.5-1.5-1.4-1.5-1.5-1.5-1.4-1.5
Mn content in liver1.92.12.71.3-1.4-1.5-1.4-1.4-1.5-1.5-1.5-1.5-1.6-1.5-1.4-1.4-1.5-1.5-1.5
Na content in liver0.10.20.20.4-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.3-0.4
Rb content in liver1.31.62.21.5-0.9-1.2-1.3-1.3-1.2-1.4-1.3-1.2-1.5-1.2-0.9-1.2-1.3-1.4-1.2
Se content in liver4.45.36.22.2-2.4-2.3-2.2-2.3-2.2-2.2-2.2-2.3-2.4-2.4-2.5-2.4-2.3-2.3-2.3
Sr content in liver0.30.31.30.2-0.9-0.5-0.4-0.4-0.5-0.3-0.5-0.5-0.3-0.5-1.1-0.6-0.5-0.3-0.5
Zn content in liver0.10.20.30.4-0.4-0.4-0.5-0.4-0.4-0.3-0.4-0.4-0.3-0.4-0.6-0.4-0.4-0.4-0.4