Hub : Genes

Ebf4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000007408 0.31 0.2 7.6e-11 0.14 0.13 0.14 0.06 5.7e-08 1.9e-07 9.3e-08 3.4e-04
2 BLA mRNA stability ENSRNOG00000007408 0.12 0.09 2.2e-03 0.05 0.02 0.03 0.04 1.6e-03 2.1e-02 1.2e-02 4.5e-03
3 Brain gene expression ENSRNOG00000007408 0.18 0.11 0.0e+00 0.18 0.17 0.17 0.18 1.3e-16 7.9e-16 5.2e-16 4.6e-16
4 Brain mRNA stability ENSRNOG00000007408 0.19 0.11 0.0e+00 0.21 0.2 0.2 0.2 2.5e-19 1.4e-18 1.3e-18 9.9e-19
5 IL mRNA stability ENSRNOG00000007408 0.39 0.21 2.1e-04 0.1 0.1 0.09 0.09 2.9e-03 2.8e-03 4.6e-03 4.6e-03
6 Liver gene expression ENSRNOG00000007408 0.47 0.13 0.0e+00 0.43 0.43 0.43 0.43 1.8e-51 4.1e-52 8.6e-52 3.4e-52
7 Liver mRNA stability ENSRNOG00000007408 0.02 0.01 8.8e-03 0 0 0 0 1.0e-01 1.1e-01 3.3e-01 3.6e-01
8 NAcc gene expression ENSRNOG00000007408 0.07 0.06 8.7e-05 0.03 0.06 0.06 0.06 4.1e-03 5.5e-05 4.9e-05 6.4e-05
9 NAcc mRNA stability ENSRNOG00000007408 0.06 0.05 1.4e-03 0.02 0.03 0.03 0.03 7.1e-03 1.3e-03 2.8e-03 3.0e-03
10 OFC gene expression ENSRNOG00000007408 0.23 0.14 6.1e-05 0.16 0.18 0.16 0.17 1.5e-04 4.6e-05 9.7e-05 7.2e-05
11 OFC mRNA stability ENSRNOG00000007408 0.19 0.12 7.7e-04 0.13 0.12 0.09 0.11 5.2e-04 8.3e-04 4.5e-03 1.3e-03
12 PL gene expression ENSRNOG00000007408 0.2 0.1 0.0e+00 0.2 0.22 0.22 0.22 1.7e-15 1.1e-16 1.4e-16 1.5e-16
13 PL mRNA stability ENSRNOG00000007408 0.14 0.08 5.4e-13 0.16 0.15 0.14 0.15 5.0e-12 1.6e-11 8.1e-11 2.1e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.03.24.71.61.32.22.01.7-1.91.81.81.71.91.61.81.9
BMI without tail3.36.89.52.31.83.12.92.6-2.72.72.62.52.82.32.62.8
Body weight5.724.127.84.73.85.35.24.9-5.15.14.84.85.14.75.05.1
Epididymis fat weight1.33.03.61.61.41.91.71.9-1.71.81.71.81.81.61.81.8
Glucose0.40.71.20.61.00.80.71.1-0.60.41.11.00.60.80.90.7
Heart weight3.95.69.81.83.12.02.12.7-2.32.02.82.82.11.82.62.1
Left kidney weight1.02.94.31.32.01.71.62.1-1.61.61.92.01.51.31.81.6
Right kidney weight1.02.94.51.22.11.71.72.1-1.61.41.92.01.51.21.81.6
Tail length4.513.517.23.62.34.14.23.5-3.84.03.53.43.93.63.73.9
Length with tail4.717.319.24.13.44.24.44.3-4.24.34.24.24.24.04.34.2
Length without tail1.53.23.61.81.71.61.81.9-1.81.81.81.91.71.91.91.8
Liver weight, left0.10.10.7-0.50.8-0.1-0.10.40.3-0.50.10.4-0.3-0.30.1-0.3
Liver weight, right0.00.10.40.2-0.70.30.3-0.1-0.00.0-0.3-0.30.10.1-0.10.2
Parametrial fat weight0.20.31.1-0.8-0.3-0.2-0.3-0.40.5-0.6-0.6-0.5-0.5-1.0-0.5-0.4
Retroperitoneal fat weight0.00.10.3-0.5-0.30.1-0.1-0.20.4-0.5-0.4-0.3-0.3-0.5-0.3-0.2
Intraocular pressure0.00.00.10.1-0.20.20.2-0.0-0.10.2-0.2-0.10.2-0.10.00.2
Extensor digitorum longus weight0.10.20.30.50.20.50.50.5-0.50.60.30.50.50.50.50.4
Soleus weight0.00.10.40.20.70.20.20.5-0.20.20.40.60.20.10.40.1
Tibialis anterior weight0.82.73.11.61.21.71.71.6-1.81.71.61.71.81.71.71.6
Tibia length4.211.914.13.72.03.83.73.2-3.63.63.33.13.73.73.43.7
Number of licking bursts0.40.51.5-0.4-1.2-0.4-0.3-0.80.6-0.5-1.0-1.0-0.4-0.3-0.7-0.3
Food consumed during 24 hour testing period0.70.81.3-1.1-0.3-0.9-1.0-0.81.1-1.2-0.6-0.8-1.1-0.8-0.9-1.0
Times rat made contact with spout0.10.10.5-0.10.7-0.0-0.00.30.2-0.20.30.3-0.10.10.1-0.0
Mean time between licks in bursts0.00.00.1-0.1-0.30.1-0.0-0.10.1-0.1-0.0-0.2-0.10.1-0.10.0
Mean num. licks in bursts0.50.62.80.41.70.40.31.0-0.50.41.11.10.30.30.80.3
Std. dev. time between licks in bursts0.50.60.80.70.70.80.70.9-0.60.60.90.80.70.80.80.8
Water consumed over 24 hours0.10.10.2-0.3-0.5-0.3-0.2-0.40.3-0.2-0.4-0.4-0.3-0.1-0.4-0.2
Indifference point 0 sec0.40.73.30.51.80.20.21.1-0.50.41.11.10.30.40.90.4
Indifference point AUC0.50.50.80.60.60.90.80.7-0.80.70.80.70.80.60.70.8
Indifference point function ln k0.10.20.60.30.80.20.20.6-0.30.20.40.70.20.10.50.3
Indifference point function log k0.10.20.60.30.80.20.20.6-0.30.20.40.70.20.10.50.3
Delay discounting total patch changes 0 sec0.50.83.60.61.90.30.31.2-0.50.41.21.20.30.50.90.4
Delay discounting total patch changes 12 sec0.50.61.10.61.00.90.70.9-0.60.51.10.80.70.70.80.8
Delay discounting total patch changes 18 sec0.40.51.1-0.70.1-0.7-1.0-0.50.9-0.9-0.4-0.4-0.9-0.7-0.6-0.9
Delay discounting total patch changes 24 sec1.11.42.6-1.60.1-1.3-1.4-0.71.4-1.4-0.9-0.6-1.4-1.4-1.0-1.3
Delay discounting total patch changes 6 sec1.01.54.40.92.10.80.71.5-0.90.81.81.60.80.81.30.7
Delay discounting time to switch 0 sec2.53.96.7-1.5-2.6-1.5-1.7-2.51.9-1.7-2.0-2.5-1.8-1.5-2.3-1.9
Delay discounting water rate 0 sec5.28.213.22.23.62.22.63.5-2.72.43.13.62.62.33.22.7
Delay discounting water rate 12 sec0.20.31.60.21.30.00.10.7-0.40.40.60.90.3-0.00.70.3
Delay discounting water rate 18 sec0.40.50.80.50.80.20.70.9-0.70.60.90.90.70.50.80.8
Delay discounting water rate 24 sec0.40.61.00.80.20.61.00.7-0.80.90.60.60.90.70.81.0
Delay discounting water rate 6 sec2.02.93.41.61.31.71.81.9-1.71.81.41.81.81.61.81.8
Locomotor activity0.10.20.40.40.30.10.40.4-0.60.50.70.30.50.70.50.7
Locomotor testing distance0.10.10.7-0.40.0-0.8-0.4-0.20.2-0.30.1-0.2-0.3-0.2-0.2-0.2
Locomotor testing rearing0.40.71.80.61.30.10.50.9-0.80.61.11.00.60.60.90.6
Light reinforcement 10.91.72.71.60.91.21.41.1-1.61.71.11.01.41.41.21.3
Light reinforcement 20.70.91.61.10.70.81.00.8-1.21.30.70.81.00.90.90.9
Reaction time number correct0.50.71.80.61.40.30.51.1-0.80.60.61.10.60.51.00.7
Reaction time mean minus median0.60.81.2-0.8-0.4-1.1-1.0-0.91.0-0.9-0.9-0.8-1.0-1.0-0.9-0.9
Reaction time mean minus median AUC0.30.41.0-0.5-0.1-1.0-0.8-0.60.7-0.6-0.6-0.5-0.7-0.7-0.6-0.7
Reaction time num false alarms2.23.04.21.51.91.51.62.0-1.71.62.02.01.61.61.81.7
Reaction time num false alarms AUC2.13.03.91.61.61.51.71.8-1.71.72.01.81.71.71.81.8
Reaction time trials correct on left0.50.71.80.61.40.30.51.1-0.80.60.61.10.60.51.00.7
Reaction time trials on left0.50.82.00.61.40.40.61.2-0.80.70.71.20.70.61.10.8
Reaction time mean0.00.00.20.3-0.50.0-0.1-0.30.1-0.1-0.1-0.3-0.10.1-0.2-0.0
Reaction time mean AUC0.00.00.20.3-0.4-0.1-0.2-0.30.1-0.1-0.1-0.3-0.10.1-0.2-0.2
Median of all reaction times0.10.10.40.6-0.30.30.20.0-0.20.20.3-0.00.20.50.10.2
Reaction time omissions0.60.91.31.11.10.50.80.9-1.00.91.21.10.80.81.00.8
Reaction time false alarm rate1.01.42.11.10.91.21.31.1-1.11.11.41.11.11.21.11.2
Reaction time premature initiation rate0.20.30.6-0.5-0.8-0.6-0.6-0.70.4-0.3-0.7-0.7-0.4-0.6-0.5-0.3
Reaction time premature initiations0.10.10.3-0.3-0.1-0.6-0.4-0.20.1-0.1-0.4-0.2-0.1-0.5-0.2-0.0
Std. dev. reaction times0.10.10.40.6-0.30.30.30.0-0.40.50.20.00.40.50.20.4
Reaction time trials completed0.50.82.00.61.40.40.61.2-0.80.70.71.20.70.61.10.8
Reaction time trials AUC0.60.82.00.71.40.40.61.2-0.90.70.81.20.80.61.10.9
Social response proportion2.52.85.91.52.41.31.61.8-1.51.41.91.91.41.51.71.3
Social responses5.36.97.62.72.42.52.82.6-2.72.72.72.62.62.72.72.5
Social time0.50.71.11.00.60.91.10.7-0.90.90.60.70.81.00.80.8
Conditioned locomotion4.75.67.52.22.52.32.22.7-2.22.22.52.72.22.22.52.3
Cocaine response after cond. corrected0.10.10.2-0.40.2-0.4-0.5-0.00.4-0.4-0.20.0-0.4-0.4-0.2-0.4
Cocaine response after cond. not corrected0.20.20.4-0.4-0.2-0.5-0.6-0.30.4-0.4-0.4-0.3-0.5-0.5-0.4-0.6
Cocaine response before conditioning0.20.20.6-0.2-0.7-0.5-0.4-0.60.3-0.2-0.6-0.6-0.3-0.4-0.5-0.4
Saline control response7.29.611.03.02.63.23.23.3-3.03.03.13.13.03.23.23.2
Condit. Reinf. active minus inactive responses2.93.64.71.82.01.61.82.1-1.91.82.02.21.81.92.11.8
Condit. Reinf. active-inactive response ratio2.72.93.41.71.61.51.61.8-1.71.61.71.81.61.81.81.7
Condit. Reinf. active responses4.66.37.92.42.62.12.42.7-2.62.42.62.82.42.42.72.4
Condit. Reinf. inactive responses1.01.32.50.91.60.80.91.3-1.11.01.21.41.00.81.30.9
Condit. Reinf. lever presses1.52.12.61.60.91.31.61.3-1.61.51.31.31.51.51.51.6
Condit. Reinf. lever reinforcers received3.65.16.62.12.51.82.12.5-2.32.12.32.62.12.12.52.1
Pavlov. Cond. lever latency3.95.36.7-2.5-1.3-2.3-2.6-2.22.5-2.4-2.1-2.1-2.5-2.5-2.3-2.5
Pavlov. Cond. magazine entry latency0.20.20.90.31.00.30.30.6-0.30.20.70.60.30.40.50.4
Pavlov. Cond. change in total contacts3.85.36.52.51.42.22.52.1-2.52.52.12.02.42.52.32.5
Pavlov. Cond. index score3.44.45.12.21.52.12.32.0-2.22.12.12.02.12.22.12.2
Pavlov. Cond. latency score2.73.43.91.91.51.82.01.8-1.91.81.91.81.81.91.91.9
Pavlov. Cond. lever contacts3.95.46.62.41.52.42.62.3-2.42.42.22.22.42.42.42.5
Pavlov. Cond. magazine entry number0.70.81.0-1.0-0.8-0.8-0.9-0.91.0-0.9-1.0-0.9-0.9-1.0-0.9-1.0
Pavlov. Cond. intertrial magazine entries1.01.31.7-1.2-0.6-1.2-1.3-1.11.2-1.2-1.1-1.0-1.2-1.3-1.1-1.3
Pavlov. Cond. lever-magazine prob. diff.3.03.94.42.11.51.92.11.9-2.02.02.01.92.02.12.02.1
Pavlov. Cond. response bias4.46.16.82.61.92.42.62.5-2.62.52.42.42.52.62.52.6
Conditioned reinforcement - actives0.00.00.1-0.30.10.10.10.1-0.10.10.00.10.1-0.40.10.1
Conditioned reinforcement - inactives0.91.04.00.62.00.40.41.3-0.80.61.21.40.60.51.10.6
Conditioned locomotion0.10.10.2-0.40.2-0.2-0.4-0.20.3-0.4-0.2-0.2-0.3-0.1-0.3-0.3
Intermittent access intake day 1-15 change0.50.50.90.21.00.70.60.9-0.60.50.70.90.60.70.80.6
Intermittent access intake escalation0.10.10.4-0.00.60.30.30.5-0.30.20.30.50.30.50.40.3
Intermittent access intake escalation 20.20.20.6-0.8-0.1-0.4-0.5-0.40.5-0.6-0.4-0.3-0.5-0.3-0.4-0.5
Intermitt. access day 1 inactive lever presses0.20.20.8-0.20.9-0.8-0.60.10.2-0.3-0.10.1-0.4-0.4-0.1-0.4
Intermitt. access day 15 inactive lever presses0.20.21.0-0.31.0-0.1-0.30.50.0-0.30.50.5-0.20.10.3-0.2
Intermitt. access escalation Index0.10.10.6-0.3-0.80.1-0.1-0.30.2-0.2-0.3-0.3-0.1-0.3-0.3-0.1
Intermittent access day 1 total infusions0.20.20.8-0.4-0.9-0.0-0.2-0.50.4-0.5-0.3-0.6-0.3-0.4-0.5-0.4
Intermittent access day 15 total infusions0.00.00.1-0.30.20.2-0.00.3-0.0-0.10.10.30.0-0.00.2-0.0
Intermittent access terminal intake (last 3 days)0.00.10.2-0.50.30.1-0.10.30.1-0.20.20.3-0.1-0.20.1-0.1
Intermittent access total infusions0.10.10.3-0.6-0.0-0.0-0.20.00.2-0.4-0.10.0-0.2-0.4-0.1-0.3
Intermittent access day 1 locomotion0.10.10.2-0.4-0.0-0.4-0.4-0.30.3-0.4-0.2-0.3-0.3-0.1-0.3-0.4
Intermittent access day 15 total locomotion0.20.21.7-0.41.3-0.2-0.40.40.1-0.30.40.5-0.3-0.10.2-0.4
Intermittent access total locomotion0.10.10.3-0.50.3-0.2-0.4-0.00.3-0.5-0.0-0.0-0.4-0.1-0.2-0.4
Intermittent access standard deviation0.10.10.2-0.1-0.10.20.30.1-0.30.20.10.10.30.50.20.3
Cocaine induced anxiety4.14.77.2-2.1-1.2-2.7-2.7-1.92.4-2.6-1.7-1.8-2.5-1.7-2.1-2.4
Post-drug Anxiety1.21.32.5-1.0-0.8-1.6-1.3-1.01.2-1.3-0.9-0.9-1.3-0.8-1.1-1.3
Baseline Anxiety0.50.51.00.60.30.81.00.6-0.81.00.50.60.90.20.70.8
Lifetime Intake0.10.10.3-0.20.10.50.30.4-0.20.00.30.40.20.10.30.2
Incentive Sensitization - Responses0.10.10.6-0.20.30.80.20.4-0.20.10.30.40.3-0.50.30.3
Incentive Sensitization - Breakpoint0.10.10.5-0.40.30.60.00.30.0-0.10.20.20.1-0.70.10.1
Progressive ratio test 1 active lever presses2.12.23.41.30.81.81.61.5-1.51.41.51.41.61.51.51.5
Progressive ratio test 1 breakpoint2.82.94.21.51.02.11.81.7-1.71.61.71.61.81.71.71.8
Progressive ratio test 1 inactive lever presses0.40.41.00.61.00.40.40.9-0.60.50.60.90.50.20.80.5
Progressive ratio test 2 active lever presses0.20.20.7-0.30.80.70.30.7-0.30.20.50.70.3-0.40.50.3
Progressive ratio test 2 breakpoint0.20.20.4-0.30.60.60.30.6-0.20.10.40.50.3-0.40.40.3
Progressive ratio test 2 inactive lever presses0.40.42.10.11.50.20.00.9-0.50.30.81.00.30.00.70.3
Total sessions with >9 infusions0.30.30.80.5-0.20.90.80.4-0.50.50.70.30.60.80.40.6
Short access day 1 total inactive lever presses0.70.81.1-0.6-1.0-0.9-1.0-1.10.8-0.8-0.9-1.0-0.8-1.1-1.0-0.8
Short access day 10 total inactive lever presses2.93.25.0-2.10.1-2.1-2.2-1.22.0-2.2-1.3-1.1-2.1-2.0-1.5-2.0
Short access day 1 total infusions0.00.00.1-0.1-0.20.2-0.00.00.0-0.10.10.00.0-0.1-0.00.1
Short access day 10 total infusions0.10.10.7-0.1-0.80.30.2-0.20.1-0.2-0.2-0.2-0.00.1-0.2-0.1
Short access total infusions0.20.20.60.1-0.20.80.60.5-0.30.30.40.40.50.50.40.5
Short access day 1 locomotion0.70.81.3-1.10.2-0.9-1.1-0.41.0-1.1-0.5-0.4-1.1-0.9-0.7-1.1
Short access day 10 total locomotion0.10.10.40.30.20.00.20.0-0.10.10.30.00.10.60.10.1
Short access total locomotion0.10.10.60.20.6-0.00.10.3-0.1-0.00.40.40.00.80.20.0
Compulsive drug intake4.24.15.1-1.8-1.9-2.1-2.0-2.32.0-1.9-2.0-2.2-2.0-2.0-2.2-2.0
One hour access (0.3 mA shock)0.10.10.7-0.80.3-0.1-0.30.10.3-0.40.10.2-0.2-0.70.0-0.2
One hour access (shock baseline)0.40.50.9-0.00.90.70.60.9-0.50.40.80.90.60.40.80.6
Number of responses in last shaping day0.10.10.3-0.2-0.3-0.6-0.6-0.40.2-0.1-0.4-0.3-0.4-0.4-0.3-0.5
Context. condit. distance diff. score0.20.31.90.21.40.20.20.7-0.20.10.60.80.1-0.00.50.0
Locomotion velocity, session 10.40.40.70.70.50.60.60.8-0.60.70.60.80.60.60.70.5
Locomotion distance, session 10.60.82.80.51.70.50.31.2-0.50.61.31.40.40.31.00.3
Locomotion velocity, session 20.10.10.2-0.50.1-0.4-0.4-0.10.3-0.2-0.1-0.0-0.3-0.4-0.1-0.3
Locomotion distance, session 21.72.44.51.22.11.31.21.8-1.41.42.02.11.31.11.81.1
Locomotion velocity, session 31.21.41.81.20.91.11.21.1-1.21.31.31.11.21.31.21.2
Locomotion distance, session 36.36.98.12.52.12.72.72.5-2.72.72.82.52.72.62.72.6
Stereotopy head waving bouts, day 30.70.92.0-0.90.4-1.4-1.3-0.50.9-1.0-0.7-0.4-1.1-1.0-0.7-1.1
Stereotopy head waving duration, day 30.50.61.3-0.7-0.2-1.1-1.0-0.50.8-0.8-0.8-0.5-0.9-0.8-0.7-0.9
Locomotion velocity, session 71.01.11.61.01.30.90.91.1-1.11.11.01.21.00.81.10.9
Locomotion distance, session 70.81.12.40.91.60.80.81.2-1.01.01.31.40.80.61.10.7
Stereotopy head waving bouts, day 70.50.50.80.80.20.70.80.7-0.80.80.50.60.80.90.70.9
Stereotopy head waving duration, day 70.10.10.30.4-0.10.40.50.3-0.40.40.10.20.40.60.30.5
Locomotion velocity, session 80.80.93.10.61.80.60.61.3-0.60.61.21.40.50.51.10.5
Locomotion distance, session 83.14.612.31.73.51.71.52.6-1.71.72.72.91.61.32.31.4
Degree of sensitization distance1.81.82.7-1.4-0.5-1.5-1.5-1.11.4-1.4-1.3-1.0-1.5-1.7-1.2-1.6
Degree of sensitization stereotypy2.02.23.21.50.41.71.81.2-1.61.61.11.11.71.81.41.8
Condit. Reinf. active minus inactive responses0.60.71.10.80.20.90.80.6-1.01.00.80.61.00.80.80.9
Condit. Reinf. active-inactive response ratio0.80.81.20.80.80.90.80.9-0.90.91.10.90.91.01.00.9
Condit. Reinf. active responses0.40.50.90.70.10.90.70.5-0.80.90.50.50.80.70.60.8
Condit. Reinf. inactive responses0.00.00.00.00.10.00.00.0-0.00.1-0.10.00.0-0.20.0-0.1
Incentive salience index mean0.30.40.60.60.30.80.60.5-0.70.80.70.50.70.60.60.7
Condit. Reinf. lever presses0.00.10.10.2-0.10.30.20.1-0.30.30.20.10.30.30.10.3
Time in familiar zone, hab. session 11.31.21.7-1.1-0.5-1.2-1.2-1.11.1-1.1-1.1-1.0-1.2-1.3-1.1-1.2
Time in novel zone, hab. session 10.60.60.80.70.80.70.70.8-0.70.70.90.80.70.70.80.7
Total zone transitions, hab. session 10.20.31.20.31.10.30.10.6-0.40.50.80.80.30.10.60.1
Total locomotion distance, hab. session 10.20.21.40.11.20.0-0.10.6-0.30.40.60.80.1-0.10.5-0.1
Locomotion velocity, hab. session 10.20.31.30.21.10.20.10.7-0.40.40.70.80.20.10.60.1
Time in familiar zone, hab. session 21.51.62.2-1.4-0.9-1.4-1.4-1.21.3-1.5-1.1-1.1-1.3-1.3-1.2-1.4
Time in novel zone, hab. session 21.61.62.11.40.81.31.41.2-1.31.51.11.11.31.31.21.4
Total zone transitions, hab. session 22.32.93.31.71.21.81.71.8-1.81.81.81.81.81.61.81.7
Total locomotion distance, hab. session 21.01.33.00.91.70.80.81.5-1.01.01.31.60.90.71.30.8
Locomotion velocity, hab. session 20.60.82.60.51.60.50.41.2-0.70.61.11.30.50.31.00.4
Novel to familiar place preference ratio0.10.10.4-0.50.1-0.3-0.3-0.10.5-0.6-0.2-0.1-0.5-0.5-0.2-0.4
Novelty place preference0.30.30.7-0.6-0.1-0.5-0.5-0.30.7-0.8-0.4-0.3-0.7-0.7-0.5-0.6
Time in novel zone, NPP test0.20.20.4-0.5-0.0-0.3-0.4-0.20.6-0.7-0.3-0.2-0.5-0.5-0.3-0.5
Total zone transitions, NPP test0.10.10.30.4-0.10.40.30.2-0.40.60.40.30.40.20.30.2
Total locomotion distance, NPP test0.40.61.90.51.40.40.31.0-0.60.60.91.10.40.20.80.2
Locomotion velocity, NPP test0.10.21.10.11.1-0.0-0.10.6-0.30.30.50.80.1-0.10.5-0.1
Pavlov. Cond. lever latency0.20.30.70.7-0.00.40.50.3-0.70.80.10.20.60.50.40.6
Pavlov. Cond. magazine entry latency0.10.10.10.20.40.20.20.2-0.30.20.30.30.30.10.30.2
Pavlov. Cond. change in total contacts0.00.00.10.10.40.10.10.2-0.10.10.30.30.10.20.20.1
Pavlov. Cond. index score0.00.00.0-0.10.10.0-0.10.00.1-0.20.10.0-0.1-0.1-0.0-0.1
Pavlov. Cond. latency score0.10.10.2-0.40.1-0.2-0.3-0.10.4-0.4-0.1-0.1-0.3-0.3-0.2-0.4
Pavlov. Cond. lever contacts0.00.10.20.00.40.30.20.3-0.0-0.00.40.30.10.20.20.1
Pavlov. Cond. magazine entry number0.40.50.8-0.90.0-0.9-0.9-0.50.8-0.8-0.5-0.4-0.9-0.8-0.6-0.9
Pavlov. Cond. intertrial magazine entries0.20.20.40.20.60.30.30.6-0.40.40.50.70.40.30.50.4
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.1-0.0-0.0-0.1-0.10.1-0.2-0.0-0.0-0.1-0.0-0.1-0.1
Pavlov. Cond. response bias0.30.40.60.70.40.70.70.6-0.60.60.60.60.70.70.60.7
Bone: apparent density0.61.12.70.41.70.80.71.2-0.70.71.41.40.80.81.20.7
Bone surface0.91.62.80.91.71.11.01.5-1.01.01.61.51.01.21.41.1
Bone volume0.91.52.80.81.71.11.01.4-1.01.01.51.51.01.11.31.0
Bone: connectivity density0.30.51.60.21.30.50.40.9-0.50.41.11.00.50.50.80.5
Bone: cortical apparent density0.50.71.21.1-0.30.90.90.3-1.01.10.40.31.01.00.61.0
Bone: cortical area3.24.95.72.11.72.42.32.3-2.22.12.22.22.22.32.32.3
Bone: cortical porosity0.20.21.00.4-1.00.40.4-0.3-0.20.2-0.3-0.50.30.4-0.20.4
Bone: cortical porosity0.40.40.70.8-0.80.80.70.0-0.60.60.1-0.20.70.80.20.8
Bone: cortical thickness1.32.22.81.40.91.71.61.5-1.51.41.41.41.61.61.51.6
Bone: cortical thickness0.20.30.40.40.10.60.60.4-0.60.40.40.40.60.60.50.6
Bone: cortical tissue density0.40.61.01.0-0.40.80.80.2-0.91.00.30.20.90.90.50.9
Bone: elastic displacement0.20.21.3-0.1-1.20.0-0.0-0.6-0.00.1-0.5-0.60.1-0.0-0.30.1
Bone: elastic work0.10.10.60.1-0.80.30.2-0.3-0.20.2-0.1-0.30.20.2-0.10.2
Bone: endosteal estimation0.51.11.51.01.11.11.01.2-1.00.91.21.21.01.11.11.0
Bone: endosteal perimeter2.34.85.92.02.12.22.22.4-2.11.92.32.42.12.22.32.1
Bone: final force3.45.56.62.31.72.62.52.4-2.32.32.42.32.42.52.42.5
Bone: final moment2.64.35.12.01.52.32.22.2-2.02.02.12.02.12.22.12.1
Bone: marrow area0.51.11.50.91.11.01.01.2-0.90.81.21.20.91.01.11.0
Bone: maximum diameter4.68.49.72.72.63.02.93.1-2.82.63.03.02.83.03.02.9
Bone: maximum force0.61.11.40.90.91.21.11.2-0.90.91.01.11.01.11.11.1
Bone: maximum moment0.30.40.70.50.60.80.70.8-0.50.40.70.70.60.70.70.7
Bone: minimum diameter1.63.03.61.61.61.81.71.9-1.71.41.81.81.71.71.81.7
Bone: periosteal estimation2.34.85.52.01.82.32.22.3-2.22.02.22.32.22.32.32.2
Bone: periosteal perimeter3.55.97.42.22.42.52.42.7-2.32.12.62.72.32.42.62.4
Bone: post-yield work0.60.81.3-1.0-0.5-0.9-0.9-0.81.0-1.1-1.0-0.9-1.0-0.9-0.9-0.9
Bone: stiffness1.82.83.41.61.51.81.71.8-1.61.51.71.71.61.71.71.6
Bone: tissue strength0.20.20.20.40.40.40.40.5-0.40.50.30.40.40.20.40.4
Bone: trabecular number0.81.21.80.71.31.11.01.2-1.01.11.21.31.00.91.21.0
Bone: trabecular spacing0.20.20.6-0.2-0.8-0.4-0.3-0.60.2-0.4-0.6-0.6-0.3-0.3-0.5-0.4
Bone: trabecular thickness0.50.61.30.51.00.60.60.9-0.60.51.10.90.60.70.90.7
Bone: trabecular tissue density1.52.22.71.51.71.51.41.6-1.41.31.61.61.41.31.51.4
Breakpoint value in progressive ratio session2.52.83.91.41.01.91.91.6-1.82.01.41.51.91.61.71.8
Distance traveled before self-admin5.45.88.11.82.72.62.52.8-2.31.82.42.72.22.42.62.2
Distance traveled after self-admin3.43.84.91.81.92.22.12.1-1.81.81.92.11.82.12.01.7
Delta time in closed arm before/after self-admin0.40.41.1-1.1-0.3-0.6-0.5-0.60.4-0.4-0.5-0.6-0.5-0.9-0.6-0.6
Delta time in open arm before/after self-admin1.61.65.00.82.20.90.91.6-0.80.61.61.80.80.51.40.8
Diff in mean of infusions in LGA sessions0.10.10.2-0.4-0.50.1-0.4-0.40.2-0.1-0.4-0.4-0.1-0.1-0.3-0.2
Extinction: sum of active levers before priming0.50.50.80.50.60.70.80.8-0.90.80.40.70.90.50.80.9
Active lever presses in extinction session 60.20.21.1-1.0-0.0-0.1-0.0-0.10.5-0.4-0.4-0.2-0.5-0.5-0.3-0.4
Delta distance traveled before/after self-admin0.30.31.01.00.00.60.40.3-0.50.80.40.30.50.70.40.4
Delta ambulatory time before/after self-admin0.60.71.6-0.1-1.3-0.5-0.7-1.10.8-0.3-0.9-1.1-0.7-0.5-1.0-0.9
Time in closed arm before self-admin0.20.30.4-0.4-0.5-0.6-0.5-0.50.6-0.5-0.6-0.6-0.5-0.3-0.6-0.3
Time in closed arm after self-admin0.90.91.4-1.2-0.9-0.8-0.9-1.20.8-0.7-0.9-1.2-0.8-1.1-1.1-0.9
Time in open arm before self-admin0.30.40.9-0.2-0.9-0.4-0.5-0.60.5-0.5-0.8-0.8-0.5-0.2-0.7-0.6
Time in open arm after self-admin0.40.41.50.51.20.40.51.0-0.30.00.71.00.30.30.70.3
Sum of active levers in priming session hrs 5-61.41.31.81.01.31.01.11.4-1.11.11.01.41.11.11.31.1
Time to tail flick, vehicle, before self-admin1.61.72.8-1.7-0.7-1.5-1.5-1.01.5-1.0-1.1-0.9-1.5-1.5-1.2-1.3
Time to tail flick, vehicle, after self-admin0.00.10.3-0.4-0.5-0.10.1-0.10.1-0.1-0.3-0.2-0.1-0.0-0.20.2
Time to tail flick, test, before self-admin1.01.02.01.40.40.90.90.6-1.11.20.80.61.11.30.91.1
Time to tail flick, test, after self-admin1.81.82.8-1.4-0.4-1.6-1.5-1.11.5-1.7-1.2-1.0-1.5-1.4-1.2-1.5
Delta time to tail flick, vehicle, before/after SA3.13.14.01.71.31.82.01.8-1.91.61.61.61.91.81.81.9
Delta time to tail flick, test, before/after SA2.22.03.0-1.7-0.2-1.7-1.5-0.91.5-1.7-1.1-0.8-1.6-1.7-1.1-1.6
Ambulatory time before self-admin4.14.36.01.72.02.52.32.3-2.02.02.02.22.01.62.22.1
Ambulatory time after self-admin4.04.56.22.01.92.52.32.2-2.02.02.02.12.02.32.11.9
Total heroin consumption3.74.45.72.41.72.11.92.1-2.22.31.92.02.12.42.12.1
Area under the delay curve0.50.51.0-0.4-1.0-0.8-0.5-0.80.4-0.4-1.0-0.9-0.5-0.5-0.8-0.6
Delay disc. indifference point, 0s delay3.74.07.5-2.0-2.2-1.6-1.7-2.01.8-1.8-2.7-2.0-1.8-2.2-2.0-1.8
Delay disc. indifference point, 16s delay0.90.91.4-0.8-1.2-1.0-0.9-1.10.8-0.7-1.0-1.2-0.8-0.6-1.1-0.9
Delay disc. indifference point, 2s delay0.10.10.2-0.0-0.2-0.5-0.1-0.20.2-0.2-0.5-0.3-0.1-0.1-0.2-0.2
Delay disc. indifference point, 24s delay2.82.73.4-1.6-1.7-1.7-1.7-1.81.6-1.5-1.6-1.8-1.6-1.4-1.8-1.6
Delay disc. indifference point, 4s delay0.10.10.4-0.0-0.60.10.1-0.2-0.30.2-0.5-0.40.20.0-0.20.1
Delay disc. indifference point, 8s delay0.60.61.6-0.4-1.3-0.8-0.6-1.00.4-0.4-1.0-1.1-0.5-0.7-0.9-0.6
Delay discount exponential model param0.40.40.90.41.00.70.50.8-0.40.40.90.90.40.40.70.5
Delay discount hyperbolic model param0.30.40.70.40.80.70.40.7-0.30.40.80.80.40.40.70.5
Fecal boli incidents, locomotor time 10.10.10.10.40.10.30.30.2-0.30.3-0.00.10.3-0.20.20.4
Change in fecal boli incidents, locomotor task0.10.10.3-0.20.0-0.3-0.4-0.20.1-0.2-0.1-0.2-0.2-0.5-0.2-0.4
Time >=10cm from walls, locomotor time 10.00.00.10.3-0.20.30.20.1-0.30.20.20.10.30.10.10.1
Bouts of movement, locomotor time 12.93.25.0-2.0-2.2-1.3-1.5-1.91.7-1.7-1.9-1.9-1.6-1.6-1.9-1.6
Total resting periods, locomotor time 12.32.64.6-1.8-2.1-1.2-1.3-1.81.4-1.4-1.8-1.8-1.4-1.5-1.7-1.4
Rest time, locomotor task time 10.30.40.8-0.5-0.9-0.5-0.6-0.80.4-0.4-0.6-0.7-0.4-0.6-0.6-0.4
Distance moved, locomotor task time 10.10.10.70.20.80.10.20.4-0.10.20.60.40.10.30.30.1
Vertical activity count, locomotor time 10.40.41.70.61.30.50.20.7-0.40.31.10.70.30.50.60.2
Time >=10cm from walls, locomotor time 20.00.00.3-0.3-0.50.10.0-0.2-0.0-0.20.0-0.2-0.1-0.1-0.2-0.3
Bouts of movement, locomotor time 21.11.13.3-1.1-1.8-0.8-0.6-1.30.9-1.1-1.0-1.4-0.8-0.7-1.1-0.8
Total resting periods, locomotor time 21.11.23.7-1.0-1.9-0.8-0.6-1.40.9-1.0-1.0-1.4-0.7-0.6-1.1-0.7
Rest time, locomotor task time 20.50.61.6-0.4-1.3-1.0-0.7-1.10.5-0.5-1.0-1.1-0.5-0.2-0.8-0.4
Distance moved, locomotor task time 20.20.21.3-0.31.10.2-0.00.60.2-0.20.60.7-0.2-0.20.3-0.2
Vertical activity count, locomotor time 20.70.73.80.31.90.60.41.1-0.40.11.31.20.20.10.80.2
Weight adjusted by age4.34.85.72.32.32.12.12.4-2.22.31.82.32.12.22.32.0
Seeking ratio, delayed vs. immediate footshock0.20.20.4-0.5-0.5-0.4-0.4-0.50.4-0.4-0.6-0.5-0.4-0.3-0.5-0.7
Locomotion in novel chamber0.10.10.4-0.2-0.6-0.6-0.3-0.40.2-0.3-0.3-0.4-0.3-0.3-0.4-0.3
Locomotion in novel chamber post-restriction1.31.52.41.21.20.81.11.2-1.31.31.11.21.21.51.31.4
Progressive ratio2.83.34.3-1.6-2.0-1.8-1.6-2.01.7-1.8-1.9-2.1-1.8-1.4-2.0-1.7
Food seeking constrained by brief footshock0.70.83.20.71.80.20.31.3-0.70.51.11.30.50.31.00.6
Seeking ratio, punishment vs. effort3.34.17.31.82.71.71.62.4-1.81.82.32.51.81.42.21.9
Run reversals in cocaine runway, females0.10.10.60.20.8-0.20.00.4-0.1-0.10.60.50.00.10.30.1
Run reversals in cocaine runway, males1.21.21.90.71.41.00.91.3-1.11.11.21.31.00.81.20.9
Latency to leave start box in cocaine runway0.70.70.9-0.8-0.8-0.7-0.8-0.90.9-1.0-0.8-1.0-0.9-0.9-0.9-0.8
Latency to leave start box in cocaine runway, F1.51.61.9-1.3-1.2-1.0-1.2-1.31.3-1.4-1.2-1.4-1.3-1.3-1.4-1.3
Latency to leave start box in cocaine runway, M0.10.10.20.20.50.20.40.4-0.20.10.30.40.30.20.30.3
Cd content in liver0.10.10.2-0.2-0.1-0.3-0.4-0.50.2-0.20.1-0.3-0.3-0.4-0.3-0.4
Co content in liver0.81.01.20.91.01.00.91.0-1.01.01.01.11.00.71.00.9
Cu content in liver2.32.83.21.71.71.61.61.8-1.61.71.71.81.61.61.81.6
Fe content in liver0.00.10.3-0.00.5-0.20.00.30.0-0.10.40.3-0.00.10.2-0.0
K content in liver0.20.20.40.30.40.70.50.5-0.40.40.50.60.50.50.50.5
Mg content in liver1.71.82.21.11.31.41.31.5-1.31.21.41.51.31.21.41.3
Mn content in liver1.92.22.51.51.11.51.41.4-1.61.61.41.41.51.61.51.5
Na content in liver0.10.10.2-0.4-0.3-0.1-0.2-0.20.4-0.4-0.2-0.2-0.3-0.1-0.2-0.2
Rb content in liver4.96.210.52.13.22.32.12.8-2.22.23.03.02.12.02.72.0
Se content in liver0.91.11.51.01.20.81.01.2-1.01.01.21.21.01.01.21.0
Sr content in liver0.40.30.50.50.30.70.70.5-0.70.60.40.50.70.50.60.7
Zn content in liver0.30.30.50.30.70.60.50.6-0.50.40.60.70.50.20.60.5