Hub : Genes

Zpbp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007255 0.15 0.09 1.0e-10 0.03 0.07 0.07 0.06 1.8e-04 9.7e-09 5.8e-08 3.6e-07
2 BLA gene expression ENSRNOG00000007255 0.06 0.04 8.3e-03 0.02 0.01 0 0.01 1.9e-02 9.1e-02 2.5e-01 1.2e-01
3 BLA intron excision ratio chr10:83560463:83563463 0.06 0.04 4.4e-03 0.01 0.02 0 0.01 1.4e-01 2.5e-02 2.0e-01 5.9e-02
4 Brain gene expression ENSRNOG00000007255 0.08 0.05 4.0e-07 0.07 0.07 0.07 0.07 3.9e-07 3.9e-07 6.6e-07 6.9e-07
5 Liver gene expression ENSRNOG00000007255 0.56 0.25 1.1e-09 0.06 0.05 0.1 0.08 3.8e-07 7.0e-06 5.0e-11 2.9e-09
6 Liver isoform ratio ENSRNOT00000048647 0.07 0.06 2.8e-03 0.02 -0 0 0.01 1.5e-03 4.8e-01 2.2e-01 4.3e-02
7 Liver isoform ratio ENSRNOT00000105871 0.06 0.05 5.5e-03 0.02 0 0 0 4.3e-03 3.7e-01 3.4e-01 8.3e-02
8 Liver intron excision ratio chr10:83560463:83563463 0.36 0.18 2.1e-03 0.04 0.01 0.03 0.03 7.7e-05 2.1e-02 2.3e-04 2.1e-04
9 Liver intron excision ratio chr10:83562581:83563463 0.24 0.13 3.8e-03 0.02 -0 0.03 0.02 1.7e-03 9.6e-01 7.1e-04 1.9e-03
10 Liver intron excision ratio chr10:83563545:83567063 0.04 0.03 2.1e-06 0.03 0.03 0.04 0.04 3.1e-04 1.3e-04 2.6e-05 6.2e-05
11 Liver intron excision ratio chr10:83566539:83567063 0.03 0.02 4.3e-03 0.02 0.01 0.01 -0 5.7e-03 1.0e-02 2.2e-02 9.3e-01
12 Liver mRNA stability ENSRNOG00000007255 0.06 0.05 1.3e-03 0.01 -0 0.01 0 2.3e-02 9.2e-01 4.8e-02 2.2e-01
13 NAcc intron excision ratio chr10:83563545:83567063 0.04 0.03 2.0e-03 0.04 0.04 0.04 0.04 1.0e-03 1.1e-03 8.1e-04 8.5e-04
14 PL gene expression ENSRNOG00000007255 0.09 0.06 1.6e-05 0.05 0.07 0.06 0.06 8.4e-05 1.0e-05 2.1e-05 1.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.86.011.9-1.4-2.4-3.2-2.7-1.9-1.51.71.7-2.0-2.83.33.5-2.4-2.6
BMI without tail0.10.21.4-0.3-0.2-0.5-0.5-0.70.1-0.00.2-1.2-0.00.40.5-0.1-0.3
Body weight3.916.629.8-3.6-4.4-5.5-4.4-3.4-1.71.71.9-2.0-5.05.25.3-5.0-4.5
Epididymis fat weight0.10.30.9-0.4-0.7-0.60.10.0-0.81.00.8-0.3-0.60.40.4-0.8-0.3
Glucose0.30.41.41.20.90.20.10.9-0.70.70.80.40.00.20.10.70.2
Heart weight2.33.35.5-2.0-1.9-2.3-2.3-1.5-0.60.40.6-0.4-2.22.32.3-2.1-2.2
Left kidney weight0.92.66.4-2.5-2.1-1.7-1.7-1.81.0-1.2-1.10.4-1.41.21.4-2.2-1.8
Right kidney weight0.20.61.1-0.7-1.0-0.9-0.4-0.9-0.40.20.3-1.0-0.71.00.9-0.9-0.5
Tail length0.20.72.4-1.5-0.8-0.7-0.4-0.81.0-1.1-0.90.8-0.60.10.1-1.3-0.7
Length with tail1.97.015.0-3.5-3.1-3.3-2.7-2.50.4-0.5-0.40.5-3.32.72.7-3.9-3.1
Length without tail2.86.211.4-2.3-2.9-3.3-2.5-1.7-1.21.11.0-0.2-3.33.13.1-3.4-2.8
Liver weight, left0.00.10.3-0.2-0.30.10.40.10.1-0.0-0.00.5-0.0-0.3-0.3-0.20.1
Liver weight, right0.30.41.20.30.70.81.10.8-0.1-0.0-0.10.00.9-0.7-0.80.40.9
Parametrial fat weight1.32.65.21.21.21.52.31.2-1.41.61.6-2.01.7-1.4-1.41.32.1
Retroperitoneal fat weight0.10.31.0-0.4-0.0-0.5-0.2-0.3-0.70.80.8-1.0-0.10.70.7-0.4-0.2
Intraocular pressure1.72.54.2-1.2-1.9-1.9-2.1-1.20.5-0.1-0.10.8-2.02.01.9-1.7-2.0
Extensor digitorum longus weight6.325.240.9-5.1-6.4-6.2-6.3-4.21.2-1.4-1.22.7-6.25.65.6-6.2-6.4
Soleus weight0.61.74.51.70.4-0.5-0.4-0.1-1.91.82.1-1.9-0.61.31.30.70.0
Tibialis anterior weight1.13.87.4-1.3-2.5-2.6-2.3-1.5-0.60.40.9-0.4-2.52.62.7-2.1-2.3
Tibia length1.64.49.1-0.5-1.9-2.6-2.2-1.0-1.82.01.9-1.3-2.73.03.0-1.7-2.1
Number of licking bursts0.60.72.41.20.40.20.40.1-1.21.31.3-1.50.00.10.10.70.5
Food consumed during 24 hour testing period0.60.71.2-0.7-0.9-1.0-1.0-0.7-0.40.60.5-0.4-1.11.01.0-1.1-1.0
Times rat made contact with spout0.91.13.61.20.90.90.90.4-1.00.90.8-1.91.0-0.6-0.51.31.2
Mean time between licks in bursts0.81.12.1-1.0-1.1-1.5-1.2-0.4-0.30.20.5-0.2-1.31.41.4-1.4-1.3
Mean num. licks in bursts0.10.20.5-0.30.20.50.30.30.4-0.5-0.50.10.7-0.5-0.50.30.3
Std. dev. time between licks in bursts0.10.20.6-0.2-0.5-0.4-0.1-0.2-0.60.20.6-0.8-0.20.40.4-0.3-0.1
Water consumed over 24 hours0.20.20.70.0-0.4-0.3-0.4-0.5-0.70.80.6-0.8-0.40.40.5-0.1-0.2
Indifference point 0 sec1.52.55.00.72.22.01.60.81.1-1.0-0.90.22.1-2.1-2.11.71.7
Indifference point AUC0.00.10.30.20.1-0.2-0.1-0.10.0-0.2-0.30.5-0.20.30.2-0.1-0.2
Indifference point function ln k0.20.20.9-0.60.10.3-0.3-0.40.9-0.8-0.60.20.2-0.6-0.50.0-0.1
Indifference point function log k0.20.20.9-0.60.10.3-0.3-0.40.9-0.8-0.60.20.2-0.6-0.50.0-0.1
Delay discounting total patch changes 0 sec1.21.93.90.62.01.71.30.51.1-1.0-1.00.21.8-1.8-1.81.41.4
Delay discounting total patch changes 12 sec3.74.98.52.32.92.62.91.7-0.70.60.6-1.22.8-2.2-2.42.72.9
Delay discounting total patch changes 18 sec0.40.51.20.61.10.90.80.20.4-0.4-0.50.00.9-0.9-0.90.90.8
Delay discounting total patch changes 24 sec1.11.42.81.41.61.51.20.50.5-0.5-0.60.41.4-1.2-1.41.71.3
Delay discounting total patch changes 6 sec1.52.35.31.22.31.91.81.00.3-0.1-0.3-0.52.2-1.7-1.81.91.9
Delay discounting time to switch 0 sec0.00.10.20.30.20.30.40.2-0.0-0.1-0.2-0.30.3-0.1-0.10.30.4
Delay discounting water rate 0 sec0.10.10.2-0.20.30.30.3-0.00.00.20.2-0.20.5-0.5-0.50.10.2
Delay discounting water rate 12 sec0.20.20.9-0.6-0.6-0.1-0.1-0.00.4-0.3-0.41.0-0.6-0.2-0.1-0.8-0.3
Delay discounting water rate 18 sec0.60.81.70.80.60.70.80.4-1.21.31.3-1.30.6-0.6-0.50.80.9
Delay discounting water rate 24 sec0.50.71.30.40.60.91.00.6-0.80.90.7-1.11.1-0.9-0.90.81.0
Delay discounting water rate 6 sec1.21.73.10.91.61.61.81.0-0.30.50.6-0.51.6-1.6-1.71.31.6
Locomotor activity0.71.12.41.40.80.61.00.6-1.31.51.4-1.60.4-0.4-0.41.01.0
Locomotor testing distance1.52.54.51.91.71.91.91.1-0.30.70.6-1.01.7-1.8-1.82.12.0
Locomotor testing rearing4.57.112.92.03.43.53.11.61.0-0.8-0.9-0.23.6-3.5-3.53.23.2
Light reinforcement 12.03.77.41.42.12.42.51.00.00.50.4-1.62.7-2.2-2.42.32.5
Light reinforcement 21.11.43.81.11.00.60.90.5-1.41.71.9-1.91.00.0-0.21.21.1
Reaction time number correct0.81.22.7-0.4-1.1-1.1-0.90.0-0.91.41.30.5-1.61.21.2-1.2-1.1
Reaction time mean minus median0.20.30.9-0.4-0.9-0.5-0.6-0.70.6-0.5-0.7-0.0-0.70.50.4-0.2-0.6
Reaction time mean minus median AUC0.10.10.20.3-0.3-0.0-0.2-0.20.4-0.2-0.4-0.1-0.20.2-0.00.5-0.1
Reaction time num false alarms0.60.81.91.41.00.50.90.5-1.11.31.2-0.70.6-0.1-0.21.00.9
Reaction time num false alarms AUC0.50.72.01.30.70.40.80.5-1.21.41.3-0.80.4-0.1-0.10.80.8
Reaction time trials correct on left0.81.22.7-0.4-1.1-1.1-0.90.0-0.91.41.30.5-1.61.21.2-1.2-1.1
Reaction time trials on left0.81.12.6-0.3-1.1-1.1-0.80.0-0.91.41.30.5-1.61.11.2-1.2-1.1
Reaction time mean0.50.71.8-0.3-0.30.80.60.11.2-1.2-1.30.30.6-1.1-1.10.40.5
Reaction time mean AUC0.50.71.8-0.4-0.30.80.50.01.2-1.2-1.30.20.6-1.1-1.10.40.5
Median of all reaction times1.01.33.10.10.41.51.20.61.0-1.1-1.20.21.3-1.8-1.71.01.2
Reaction time omissions0.71.02.00.90.81.21.40.7-0.50.60.4-1.01.2-0.9-1.11.21.4
Reaction time false alarm rate0.60.91.81.31.10.91.10.4-0.60.50.4-0.91.2-0.6-0.71.31.2
Reaction time premature initiation rate0.40.62.40.50.30.70.90.2-0.70.70.9-1.50.2-0.8-0.80.50.8
Reaction time premature initiations0.40.52.1-0.0-0.5-0.20.1-0.1-1.11.31.4-1.2-0.8-0.00.1-0.4-0.0
Std. dev. reaction times0.10.10.4-0.1-0.60.1-0.0-0.20.5-0.4-0.6-0.2-0.2-0.1-0.20.20.0
Reaction time trials completed0.81.12.6-0.3-1.1-1.1-0.80.0-0.91.41.30.5-1.61.11.2-1.2-1.1
Reaction time trials AUC0.71.02.4-0.3-1.0-1.0-0.80.0-0.71.21.10.7-1.61.01.1-1.1-1.0
Social response proportion0.30.30.8-0.1-0.3-0.6-0.9-0.60.10.00.1-0.2-0.50.80.9-0.1-0.7
Social responses0.40.51.70.60.5-0.10.20.3-0.91.21.1-1.30.30.40.40.40.3
Social time0.91.23.70.7-0.4-0.7-0.00.2-1.81.91.7-1.7-0.61.01.1-0.10.0
Conditioned locomotion0.30.40.8-0.00.50.50.4-0.10.8-0.9-0.90.90.6-0.7-0.70.30.3
Cocaine response after cond. corrected1.31.44.92.21.50.60.81.0-1.61.41.5-0.90.5-0.00.01.41.0
Cocaine response after cond. not corrected1.61.86.72.61.60.70.91.3-1.71.61.7-0.70.5-0.1-0.11.71.1
Cocaine response before conditioning0.20.20.90.60.20.60.10.40.3-0.1-0.20.90.2-0.4-0.50.70.2
Saline control response0.40.51.50.9-0.1-0.5-0.60.2-0.81.11.2-0.0-0.90.90.90.1-0.4
Condit. Reinf. active minus inactive responses0.70.92.00.90.91.11.41.1-0.70.60.6-0.41.0-0.9-1.10.91.3
Condit. Reinf. active-inactive response ratio0.80.91.60.80.80.81.21.0-1.11.00.9-1.10.9-0.5-0.70.71.2
Condit. Reinf. active responses1.31.83.51.41.31.41.91.4-1.21.21.2-1.11.3-1.1-1.21.31.7
Condit. Reinf. inactive responses1.41.83.01.71.61.41.71.3-0.81.01.0-0.71.3-1.1-1.21.61.6
Condit. Reinf. lever presses0.10.10.40.00.10.50.40.30.0-0.2-0.10.10.3-0.7-0.60.20.3
Condit. Reinf. lever reinforcers received1.21.83.61.21.31.51.91.3-0.81.00.9-0.81.4-1.4-1.41.31.7
Pavlov. Cond. lever latency0.30.40.6-0.6-0.4-0.7-0.8-0.70.6-0.8-0.80.7-0.50.70.6-0.6-0.7
Pavlov. Cond. magazine entry latency0.20.20.90.2-0.5-0.3-0.10.2-0.80.90.9-0.1-0.60.40.2-0.2-0.2
Pavlov. Cond. change in total contacts0.50.71.50.60.91.11.01.00.10.00.10.10.9-1.2-1.20.80.9
Pavlov. Cond. index score0.30.41.20.70.30.40.50.7-0.91.11.1-0.70.2-0.2-0.30.50.5
Pavlov. Cond. latency score0.30.31.10.60.10.20.30.6-0.91.01.0-0.60.1-0.1-0.10.40.3
Pavlov. Cond. lever contacts0.81.11.61.20.80.91.11.0-1.11.31.3-1.20.7-0.7-0.71.11.1
Pavlov. Cond. magazine entry number0.20.21.0-0.5-0.0-0.1-0.1-0.20.7-1.0-0.90.50.1-0.00.1-0.4-0.1
Pavlov. Cond. intertrial magazine entries1.92.54.7-1.9-1.6-0.9-1.4-1.22.0-2.2-2.22.0-1.10.50.4-1.6-1.5
Pavlov. Cond. lever-magazine prob. diff.0.30.31.20.60.10.20.40.5-0.91.11.1-0.70.1-0.1-0.20.40.3
Pavlov. Cond. response bias1.01.41.91.41.01.11.31.2-1.11.31.3-1.00.9-0.9-1.01.31.3
Conditioned reinforcement - actives0.60.61.10.90.61.00.80.8-0.2-0.1-0.11.00.4-1.0-1.00.70.7
Conditioned reinforcement - inactives1.41.63.10.71.51.71.61.30.3-0.4-0.40.71.7-1.8-1.51.11.5
Conditioned locomotion0.50.61.51.20.90.80.70.5-0.70.50.5-0.20.3-0.9-0.80.90.7
Intermittent access intake day 1-15 change0.40.40.90.00.00.80.90.30.3-0.2-0.3-0.40.7-1.0-0.90.50.8
Intermittent access intake escalation0.40.30.90.00.10.80.90.30.1-0.1-0.1-0.40.7-1.0-0.90.40.8
Intermittent access intake escalation 20.10.10.4-0.2-0.40.00.3-0.1-0.20.20.2-0.60.1-0.2-0.1-0.10.2
Intermitt. access day 1 inactive lever presses1.61.84.40.41.21.41.80.9-0.50.50.5-1.62.1-1.6-1.51.41.7
Intermitt. access day 15 inactive lever presses3.33.77.11.42.22.42.31.40.3-0.0-0.0-0.72.7-2.5-2.52.42.3
Intermitt. access escalation Index1.61.53.5-0.7-1.9-1.4-1.7-1.10.1-0.0-0.0-0.3-1.51.71.5-1.1-1.4
Intermittent access day 1 total infusions0.20.30.70.50.60.40.60.9-0.80.70.60.30.1-0.4-0.40.10.4
Intermittent access day 15 total infusions0.40.51.00.30.61.01.00.8-0.0-0.0-0.10.20.7-1.0-1.00.50.9
Intermittent access terminal intake (last 3 days)0.50.51.20.40.71.01.10.9-0.30.20.2-0.00.9-1.0-0.90.51.0
Intermittent access total infusions0.20.20.60.10.40.50.70.7-0.30.20.20.50.3-0.6-0.5-0.00.5
Intermittent access day 1 locomotion0.20.21.00.51.00.60.40.5-0.20.00.00.50.4-0.5-0.50.40.4
Intermittent access day 15 total locomotion0.40.40.60.70.70.70.60.4-0.70.60.6-0.60.4-0.5-0.60.70.7
Intermittent access total locomotion0.60.71.60.61.31.11.00.60.1-0.2-0.30.20.8-1.2-1.20.80.9
Intermittent access standard deviation1.61.73.80.01.11.71.90.70.8-1.0-1.00.31.6-2.0-1.90.81.6
Cocaine induced anxiety2.22.54.9-0.8-1.4-2.0-1.4-1.1-1.41.61.7-2.2-1.51.91.9-1.5-1.3
Post-drug Anxiety0.30.41.00.1-0.2-0.6-0.5-0.2-0.51.01.0-0.9-0.60.70.7-0.3-0.4
Baseline Anxiety1.61.72.81.21.31.70.90.81.6-1.1-1.11.61.1-1.5-1.51.61.1
Lifetime Intake0.20.20.60.00.40.60.80.8-0.30.20.20.40.4-0.7-0.70.00.6
Incentive Sensitization - Responses1.11.11.81.11.21.31.31.3-0.20.10.10.71.0-1.2-1.21.01.2
Incentive Sensitization - Breakpoint1.11.11.91.21.21.31.31.4-0.30.30.20.61.0-1.2-1.11.01.2
Progressive ratio test 1 active lever presses0.50.51.20.91.10.90.60.6-0.1-0.2-0.20.50.8-0.8-0.70.90.7
Progressive ratio test 1 breakpoint0.40.41.00.81.00.80.50.6-0.2-0.2-0.20.40.7-0.7-0.60.90.6
Progressive ratio test 1 inactive lever presses1.21.32.80.41.31.51.40.60.3-0.7-0.7-0.21.7-1.6-1.51.21.4
Progressive ratio test 2 active lever presses1.11.12.01.01.31.41.31.20.1-0.2-0.31.01.0-1.4-1.31.01.2
Progressive ratio test 2 breakpoint0.80.91.50.91.11.21.01.10.1-0.2-0.30.90.8-1.2-1.10.91.0
Progressive ratio test 2 inactive lever presses0.40.51.00.30.80.91.00.9-0.30.10.00.40.8-1.0-0.80.40.8
Total sessions with >9 infusions0.70.71.40.31.21.00.70.20.6-1.0-1.00.41.1-1.0-1.01.00.8
Short access day 1 total inactive lever presses1.51.73.50.81.41.71.81.1-0.00.10.1-0.41.9-1.5-1.61.51.7
Short access day 10 total inactive lever presses0.20.21.2-0.9-0.6-0.30.0-0.60.30.00.0-1.1-0.00.10.2-0.4-0.0
Short access day 1 total infusions0.60.71.6-0.01.11.01.00.80.2-0.5-0.50.51.3-1.1-1.10.60.9
Short access day 10 total infusions0.40.40.80.60.60.60.80.9-0.80.80.7-0.20.5-0.6-0.50.40.7
Short access total infusions0.30.30.8-0.20.50.70.80.60.2-0.4-0.40.60.6-0.9-0.90.10.6
Short access day 1 locomotion2.93.16.51.12.52.22.11.3-0.1-0.4-0.4-0.52.6-2.1-2.22.02.2
Short access day 10 total locomotion1.11.23.41.41.81.31.20.9-0.30.20.1-0.21.2-1.1-1.21.41.3
Short access total locomotion0.60.61.30.11.10.90.70.30.7-0.9-0.90.60.9-0.9-1.00.70.7
Compulsive drug intake1.61.65.7-1.0-0.4-0.2-0.9-0.82.4-2.2-2.21.9-0.50.10.1-0.5-0.8
One hour access (0.3 mA shock)0.10.11.0-0.1-0.30.20.10.10.4-0.4-0.51.0-0.2-0.3-0.2-0.2-0.0
One hour access (shock baseline)0.40.51.20.60.30.50.80.8-1.11.00.9-0.30.5-0.5-0.40.30.7
Number of responses in last shaping day0.90.92.0-0.40.90.90.80.31.1-1.4-1.41.01.1-1.0-1.00.40.7
Context. condit. distance diff. score1.31.63.1-1.4-1.4-0.8-1.6-1.21.3-1.4-1.51.7-1.10.50.4-1.0-1.5
Locomotion velocity, session 10.40.41.1-0.4-0.4-0.9-0.5-0.5-0.60.60.6-0.5-0.61.01.1-0.7-0.5
Locomotion distance, session 12.12.74.9-1.4-1.4-2.2-1.4-1.5-1.21.21.2-1.6-1.82.22.2-1.9-1.5
Locomotion velocity, session 20.20.20.7-0.8-0.3-0.4-0.2-0.60.4-0.6-0.4-0.2-0.20.20.3-0.6-0.3
Locomotion distance, session 20.60.93.4-0.3-0.0-0.90.1-0.5-1.41.31.4-1.9-0.50.90.9-0.7-0.1
Locomotion velocity, session 30.30.30.8-0.8-0.10.30.3-0.50.8-0.9-0.8-0.30.5-0.6-0.6-0.20.2
Locomotion distance, session 30.20.20.6-0.7-0.6-0.5-0.3-0.80.2-0.3-0.2-0.4-0.30.40.3-0.5-0.4
Stereotopy head waving bouts, day 31.82.24.11.31.82.01.51.10.5-0.4-0.5-0.31.9-1.8-1.82.01.7
Stereotopy head waving duration, day 30.10.10.30.40.40.50.10.40.10.1-0.0-0.50.4-0.3-0.30.60.3
Locomotion velocity, session 70.80.92.0-0.4-0.9-1.4-0.9-0.6-0.50.60.50.1-1.41.41.3-1.0-1.1
Locomotion distance, session 70.30.41.4-0.1-0.3-0.8-0.7-0.1-0.10.1-0.01.2-0.90.90.8-0.6-0.8
Stereotopy head waving bouts, day 70.40.51.80.90.70.70.60.0-0.20.40.3-1.40.7-0.5-0.51.10.8
Stereotopy head waving duration, day 70.20.31.40.40.40.50.5-0.2-0.00.10.2-1.20.6-0.4-0.40.70.6
Locomotion velocity, session 85.16.110.0-2.7-3.0-3.1-3.1-2.30.5-0.4-0.50.8-3.12.72.7-3.1-3.2
Locomotion distance, session 80.91.42.3-1.2-1.3-1.5-1.3-1.1-0.30.30.2-0.1-1.51.51.4-1.5-1.4
Degree of sensitization distance0.80.82.3-0.4-0.7-1.0-1.2-0.10.1-0.1-0.21.5-1.31.11.0-0.9-1.2
Degree of sensitization stereotypy0.70.81.71.30.90.90.80.3-0.50.60.7-1.20.7-0.6-0.61.31.0
Condit. Reinf. active minus inactive responses1.01.12.40.11.01.31.10.21.2-1.1-1.20.31.3-1.5-1.60.91.0
Condit. Reinf. active-inactive response ratio1.61.73.4-0.10.91.51.00.31.8-1.7-1.81.01.3-1.8-1.80.91.0
Condit. Reinf. active responses0.81.02.10.41.01.31.10.41.0-0.8-0.90.31.2-1.4-1.51.11.1
Condit. Reinf. inactive responses0.20.21.01.00.30.30.30.4-0.50.60.6-0.20.2-0.0-0.10.70.4
Incentive salience index mean1.51.83.30.81.61.71.60.90.6-0.5-0.6-0.11.8-1.7-1.81.51.6
Condit. Reinf. lever presses0.71.02.11.11.41.11.20.9-0.20.30.2-0.41.2-0.8-1.01.31.2
Time in familiar zone, hab. session 11.71.65.01.40.70.00.51.2-2.22.22.1-1.50.30.60.50.70.6
Time in novel zone, hab. session 11.41.43.2-0.20.81.20.5-0.41.8-1.7-1.70.71.1-1.5-1.50.90.6
Total zone transitions, hab. session 11.21.62.7-1.6-1.6-1.6-1.5-1.20.4-0.3-0.30.3-1.41.41.4-1.6-1.5
Total locomotion distance, hab. session 10.00.00.2-0.5-0.30.1-0.1-0.20.1-0.1-0.1-0.10.0-0.2-0.2-0.1-0.1
Locomotion velocity, hab. session 10.20.41.2-1.0-1.1-0.5-0.5-0.40.2-0.2-0.30.4-0.60.30.3-0.9-0.6
Time in familiar zone, hab. session 20.70.71.40.90.80.50.80.8-1.21.11.2-1.10.7-0.3-0.30.80.8
Time in novel zone, hab. session 20.40.41.2-0.20.30.60.4-0.11.1-0.9-1.10.40.6-0.8-0.70.30.4
Total zone transitions, hab. session 20.70.91.7-0.7-0.7-1.2-1.2-0.9-0.40.40.4-0.2-1.21.31.3-0.9-1.1
Total locomotion distance, hab. session 20.50.61.5-0.1-0.5-0.7-0.5-0.3-1.11.11.1-1.2-0.70.90.9-0.3-0.4
Locomotion velocity, hab. session 20.50.71.1-0.3-0.7-0.9-0.7-0.5-1.01.01.0-0.8-1.01.11.1-0.6-0.7
Novel to familiar place preference ratio1.41.53.0-1.3-1.4-0.8-1.0-0.91.7-1.5-1.61.7-0.90.40.4-1.2-1.2
Novelty place preference1.61.74.1-1.2-1.2-0.6-1.0-0.92.0-1.9-1.92.0-0.70.20.2-1.0-1.1
Time in novel zone, NPP test1.01.13.4-0.8-0.8-0.2-0.6-0.61.8-1.7-1.71.8-0.3-0.1-0.1-0.5-0.7
Total zone transitions, NPP test0.81.22.80.0-0.4-1.2-0.8-0.4-1.51.41.4-0.8-1.11.71.5-0.8-0.7
Total locomotion distance, NPP test0.60.82.60.40.1-0.4-0.10.0-1.61.51.6-1.5-0.30.90.80.10.1
Locomotion velocity, NPP test0.60.91.7-0.2-0.5-0.9-0.7-0.4-1.31.21.3-1.1-0.81.31.2-0.6-0.5
Pavlov. Cond. lever latency2.43.05.3-2.3-2.1-1.5-2.0-1.51.6-1.6-1.71.7-1.70.91.0-2.1-2.1
Pavlov. Cond. magazine entry latency6.88.815.23.53.63.53.62.6-1.31.21.2-1.83.5-2.8-2.93.93.8
Pavlov. Cond. change in total contacts6.36.712.32.23.13.43.01.90.5-0.4-0.5-0.63.5-3.1-3.23.33.2
Pavlov. Cond. index score5.97.512.73.43.43.03.22.4-1.71.61.7-2.13.0-2.2-2.33.63.4
Pavlov. Cond. latency score4.65.910.03.22.92.52.82.1-1.81.71.8-2.02.6-1.7-1.83.13.0
Pavlov. Cond. lever contacts2.22.64.92.21.71.31.71.5-1.81.71.7-1.61.4-0.7-0.81.91.8
Pavlov. Cond. magazine entry number8.410.618.9-3.7-4.0-4.0-3.9-2.81.1-1.1-1.11.9-4.03.23.3-4.3-4.1
Pavlov. Cond. intertrial magazine entries1.31.52.3-1.5-1.2-1.2-1.4-1.21.2-1.3-1.21.0-1.20.80.8-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.6.48.013.93.43.53.23.42.5-1.51.41.5-1.93.3-2.5-2.63.73.6
Pavlov. Cond. response bias6.37.713.73.13.43.43.32.3-0.90.90.8-1.53.4-2.8-2.93.73.5
Bone: apparent density1.62.74.81.81.81.91.90.8-0.70.50.6-2.02.0-1.5-1.62.12.2
Bone surface0.30.52.70.40.1-0.20.2-0.1-1.21.01.2-1.70.10.60.50.10.3
Bone volume0.71.25.11.00.40.10.50.3-1.81.61.7-2.30.30.50.40.60.7
Bone: connectivity density2.13.36.21.82.02.32.20.9-0.20.00.0-1.62.4-2.0-2.12.42.5
Bone: cortical apparent density4.86.211.31.82.83.42.72.21.1-0.9-1.10.93.2-3.3-3.33.02.8
Bone: cortical area0.10.10.30.50.30.30.20.20.00.40.2-0.10.1-0.2-0.20.50.2
Bone: cortical porosity0.40.51.51.20.30.10.30.5-1.21.11.0-0.60.20.20.30.70.3
Bone: cortical porosity0.60.72.11.40.2-0.10.10.6-1.41.41.3-0.6-0.10.50.60.70.2
Bone: cortical thickness0.81.32.81.11.11.61.00.60.9-0.3-0.70.21.2-1.6-1.61.71.1
Bone: cortical thickness3.84.48.91.71.92.92.41.90.8-0.4-0.80.42.6-2.7-3.02.62.5
Bone: cortical tissue density4.86.211.21.82.83.32.72.21.1-0.9-1.10.93.2-3.3-3.33.02.8
Bone: elastic displacement0.00.00.2-0.1-0.10.1-0.1-0.00.2-0.1-0.3-0.4-0.0-0.1-0.10.2-0.0
Bone: elastic work0.20.21.30.2-0.10.10.40.1-0.50.90.9-1.10.0-0.1-0.10.20.3
Bone: endosteal estimation1.94.19.4-1.0-1.7-2.7-1.9-1.2-1.81.31.7-0.7-2.43.13.0-2.3-2.0
Bone: endosteal perimeter1.02.14.3-1.2-1.6-2.0-1.4-0.6-0.80.60.80.5-1.62.12.0-2.0-1.6
Bone: final force0.91.53.91.91.10.50.80.7-1.71.82.0-1.50.40.0-0.01.21.0
Bone: final moment0.91.44.21.80.90.30.60.5-1.71.92.1-1.70.30.30.21.00.8
Bone: marrow area1.83.98.9-1.0-1.6-2.6-1.9-1.1-1.81.31.7-0.7-2.33.02.9-2.2-1.9
Bone: maximum diameter0.10.10.40.40.20.10.30.2-0.50.50.6-0.20.10.10.00.20.2
Bone: maximum force0.40.62.30.70.1-0.4-0.2-0.1-1.21.31.5-1.2-0.50.80.80.1-0.1
Bone: maximum moment0.40.72.20.6-0.1-0.6-0.4-0.3-1.11.31.5-1.3-0.61.01.0-0.1-0.3
Bone: minimum diameter0.50.81.8-0.4-0.6-1.2-0.9-0.5-0.60.81.1-0.4-1.11.31.3-1.0-0.9
Bone: periosteal estimation0.40.91.90.1-0.4-1.0-0.6-0.3-1.21.21.4-0.7-0.91.41.3-0.7-0.6
Bone: periosteal perimeter0.81.32.7-0.3-1.1-1.4-0.9-0.3-1.11.31.4-0.4-1.21.61.6-1.1-1.0
Bone: post-yield work1.11.52.5-1.1-1.4-1.6-1.6-1.3-0.2-0.00.3-0.4-1.51.51.5-1.4-1.5
Bone: stiffness0.20.31.00.60.2-0.2-0.10.1-0.90.91.0-0.5-0.20.50.50.1-0.0
Bone: tissue strength0.70.71.4-0.7-1.0-1.0-1.2-1.10.30.00.2-0.4-1.10.91.0-0.7-1.1
Bone: trabecular number3.65.69.72.92.72.72.91.8-1.31.01.2-2.22.8-2.1-2.23.03.1
Bone: trabecular spacing1.41.94.3-0.3-1.1-1.8-1.4-0.2-1.21.41.00.1-1.72.12.1-1.4-1.4
Bone: trabecular thickness0.10.21.00.1-0.10.40.4-0.1-0.10.10.2-1.00.5-0.2-0.30.40.5
Bone: trabecular tissue density1.11.55.1-0.90.10.5-0.3-0.62.1-2.3-2.21.70.4-0.9-0.9-0.0-0.2
Breakpoint value in progressive ratio session0.20.21.0-0.7-0.1-0.10.60.7-0.1-0.10.10.3-0.5-0.5-0.4-1.00.1
Distance traveled before self-admin0.50.52.00.2-0.2-0.30.21.1-1.41.21.10.3-0.40.20.3-0.6-0.1
Distance traveled after self-admin1.11.22.4-1.1-1.3-1.4-1.10.0-1.00.70.6-0.2-1.21.31.4-1.6-1.2
Delta time in closed arm before/after self-admin2.72.74.6-1.6-2.1-2.1-1.9-1.70.1-0.0-0.1-0.3-2.02.22.0-1.7-1.9
Delta time in open arm before/after self-admin0.00.00.20.20.00.1-0.10.4-0.10.10.40.2-0.0-0.10.00.1-0.1
Diff in mean of infusions in LGA sessions0.20.20.6-0.5-0.7-0.20.30.50.00.0-0.10.0-0.7-0.2-0.2-0.8-0.0
Extinction: sum of active levers before priming1.21.22.8-0.6-1.0-1.5-1.4-1.1-0.30.00.4-0.4-1.31.51.7-1.2-1.3
Active lever presses in extinction session 63.23.09.31.61.70.51.61.5-3.12.72.7-2.20.8-0.4-0.30.71.4
Delta distance traveled before/after self-admin1.21.32.0-1.3-1.4-1.2-1.4-1.40.7-0.9-0.80.1-1.11.11.1-1.1-1.3
Delta ambulatory time before/after self-admin0.91.02.2-0.8-1.1-1.2-1.3-1.50.3-0.5-0.3-0.9-0.81.21.2-0.7-1.0
Time in closed arm before self-admin1.01.13.30.21.11.40.81.00.8-0.9-0.80.11.8-1.4-1.31.21.0
Time in closed arm after self-admin1.21.24.0-1.5-1.0-0.3-0.9-0.92.0-1.7-1.61.1-0.10.20.1-0.7-0.8
Time in open arm before self-admin1.51.64.6-1.1-1.3-1.6-1.0-0.9-0.20.0-0.31.0-2.21.41.3-2.0-1.3
Time in open arm after self-admin0.40.41.3-0.4-0.5-0.7-0.50.1-0.40.30.10.7-1.10.80.6-1.0-0.7
Sum of active levers in priming session hrs 5-60.40.41.40.71.20.40.60.5-0.60.50.7-0.60.6-0.3-0.30.60.6
Time to tail flick, vehicle, before self-admin0.40.41.20.40.10.10.00.4-1.11.01.1-1.10.20.00.10.40.2
Time to tail flick, vehicle, after self-admin0.30.31.10.70.40.00.20.2-1.10.80.7-0.80.00.10.00.40.3
Time to tail flick, test, before self-admin1.11.02.3-0.8-1.5-1.2-1.2-1.2-0.10.0-0.1-0.3-1.51.11.0-1.2-1.2
Time to tail flick, test, after self-admin1.31.34.20.70.80.10.30.8-2.02.02.0-1.90.30.40.20.60.4
Delta time to tail flick, vehicle, before/after SA0.80.82.71.10.70.10.60.4-1.71.51.0-1.30.20.20.00.50.6
Delta time to tail flick, test, before/after SA2.52.24.91.52.21.51.51.9-1.21.31.3-0.81.7-1.0-1.11.81.5
Ambulatory time before self-admin0.20.20.7-0.3-0.3-0.30.00.8-0.80.60.50.7-0.30.10.2-0.7-0.3
Ambulatory time after self-admin2.02.23.8-1.4-1.7-1.9-1.4-0.4-1.41.11.1-1.3-1.31.71.9-1.8-1.4
Total heroin consumption2.63.27.21.51.41.12.02.0-2.62.72.4-2.20.9-1.0-1.00.91.8
Area under the delay curve0.30.30.60.60.70.60.40.3-0.0-0.1-0.0-0.50.7-0.7-0.70.70.5
Delay disc. indifference point, 0s delay0.91.01.61.01.31.21.11.2-0.30.50.3-0.61.0-1.1-1.21.11.1
Delay disc. indifference point, 16s delay1.01.02.70.00.70.90.20.21.5-1.6-1.51.11.1-0.9-1.00.70.3
Delay disc. indifference point, 2s delay1.41.53.11.81.41.01.01.0-1.51.51.5-1.40.8-0.7-0.71.41.1
Delay disc. indifference point, 24s delay0.20.21.1-0.10.10.0-0.4-0.40.6-1.0-0.60.20.2-0.1-0.10.1-0.2
Delay disc. indifference point, 4s delay0.70.71.21.00.80.91.00.8-0.71.00.7-0.50.7-1.1-1.00.80.9
Delay disc. indifference point, 8s delay0.10.10.40.40.50.40.1-0.10.2-0.3-0.2-0.40.6-0.4-0.30.50.3
Delay discount exponential model param0.10.10.3-0.4-0.4-0.4-0.2-0.10.00.1-0.00.5-0.50.50.5-0.5-0.3
Delay discount hyperbolic model param0.20.20.5-0.5-0.6-0.6-0.3-0.20.2-0.2-0.20.6-0.60.70.6-0.7-0.4
Fecal boli incidents, locomotor time 10.20.20.5-0.1-0.1-0.6-0.5-0.1-0.50.10.5-0.2-0.60.70.7-0.5-0.5
Change in fecal boli incidents, locomotor task0.00.00.30.2-0.0-0.0-0.20.1-0.00.10.10.5-0.40.10.1-0.0-0.2
Time >=10cm from walls, locomotor time 10.70.72.10.30.80.70.10.01.3-1.3-1.51.50.4-0.8-0.70.60.2
Bouts of movement, locomotor time 10.50.51.5-0.7-1.0-0.9-0.6-1.20.3-0.8-0.1-0.4-0.60.60.7-0.7-0.7
Total resting periods, locomotor time 10.91.01.9-0.7-1.3-1.3-0.9-1.4-0.1-0.50.2-0.5-1.11.21.2-1.0-1.0
Rest time, locomotor task time 10.20.21.80.10.0-0.10.1-0.2-0.6-0.10.7-1.30.30.20.30.20.2
Distance moved, locomotor task time 10.20.21.10.50.50.30.20.90.20.4-0.41.10.1-0.2-0.20.30.2
Vertical activity count, locomotor time 10.20.21.10.1-0.0-0.3-0.30.4-0.21.10.00.8-0.90.20.3-0.4-0.4
Time >=10cm from walls, locomotor time 21.01.12.81.71.41.21.00.90.2-0.3-0.21.60.3-1.1-1.01.00.9
Bouts of movement, locomotor time 20.80.83.1-0.30.10.60.4-0.61.5-1.8-1.40.90.8-0.9-0.80.40.3
Total resting periods, locomotor time 20.91.04.0-0.6-0.10.40.2-0.81.7-2.0-1.60.90.7-0.8-0.80.20.2
Rest time, locomotor task time 20.60.71.4-0.9-0.9-1.1-0.9-1.00.1-0.40.1-0.3-0.91.00.9-1.2-0.9
Distance moved, locomotor task time 20.20.20.60.40.4-0.3-0.30.6-0.40.70.10.4-0.20.60.70.2-0.2
Vertical activity count, locomotor time 20.20.20.8-0.1-0.1-0.5-0.70.0-0.10.9-0.10.3-0.70.50.7-0.3-0.6
Weight adjusted by age0.40.41.20.3-1.0-0.7-0.3-0.0-0.60.90.6-0.0-1.10.70.7-0.6-0.4
Seeking ratio, delayed vs. immediate footshock1.11.34.4-0.60.10.90.50.62.0-1.1-1.62.10.6-1.2-1.30.10.3
Locomotion in novel chamber4.25.29.12.83.02.72.62.6-1.01.20.9-0.12.3-2.4-2.32.72.6
Locomotion in novel chamber post-restriction2.22.66.71.51.10.71.31.3-2.42.52.5-2.60.8-0.5-0.51.01.3
Progressive ratio0.10.10.40.50.60.10.60.5-0.10.20.40.30.2-0.2-0.20.10.4
Food seeking constrained by brief footshock0.30.40.80.60.70.30.60.6-0.70.90.8-0.90.7-0.1-0.20.50.6
Seeking ratio, punishment vs. effort0.00.00.20.1-0.20.1-0.4-0.1-0.00.1-0.2-0.40.10.10.10.3-0.1
Run reversals in cocaine runway, females2.42.43.8-1.9-1.6-1.2-1.7-1.11.5-1.4-1.41.8-1.80.91.1-1.8-1.8
Run reversals in cocaine runway, males0.50.50.90.90.90.70.61.0-0.50.60.50.00.7-0.6-0.60.70.6
Latency to leave start box in cocaine runway1.21.32.8-1.4-1.3-1.3-1.2-0.4-0.0-0.1-0.11.2-1.41.31.2-1.7-1.4
Latency to leave start box in cocaine runway, F1.31.43.1-1.1-1.5-1.4-1.2-0.2-0.50.40.31.1-1.71.41.3-1.7-1.4
Latency to leave start box in cocaine runway, M0.40.41.0-0.80.60.50.4-0.00.8-0.9-0.80.31.0-0.7-0.70.20.3
Cd content in liver0.20.21.10.10.50.30.3-0.2-0.20.30.4-1.00.5-0.4-0.30.40.4
Co content in liver0.60.71.9-1.4-1.1-0.7-0.7-0.60.7-0.9-0.90.6-0.50.50.5-1.0-0.8
Cu content in liver0.30.41.2-1.1-0.00.10.2-0.30.8-0.9-0.90.70.3-0.5-0.5-0.6-0.0
Fe content in liver0.80.91.7-0.8-1.1-1.3-0.9-0.7-0.40.60.6-0.5-1.21.31.2-1.2-1.0
K content in liver1.01.02.00.81.31.21.40.9-0.1-0.1-0.10.21.2-1.3-1.30.81.2
Mg content in liver1.81.93.60.11.01.51.10.51.5-1.7-1.71.71.4-1.9-1.90.70.9
Mn content in liver1.92.24.60.41.61.91.80.60.8-1.0-1.10.32.0-2.2-2.21.21.7
Na content in liver0.70.72.31.20.50.10.70.8-1.51.41.4-0.90.10.20.20.40.6
Rb content in liver1.11.43.40.91.81.51.31.10.2-0.2-0.2-0.01.6-1.4-1.41.31.4
Se content in liver4.04.89.11.42.42.82.92.00.4-0.5-0.60.43.0-2.9-2.92.12.7
Sr content in liver0.50.41.0-0.60.20.50.40.11.0-1.0-1.01.00.4-0.8-0.8-0.20.2
Zn content in liver2.22.44.81.21.62.02.11.6-0.20.20.2-0.52.2-1.8-1.81.72.0