Hub : Genes

Preb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000007141 0.03 0.03 2.4e-03 0.02 0.02 0.02 0.02 1.1e-03 1.8e-03 1.4e-03 1.9e-03
2 BLA gene expression ENSRNOG00000007141 0.14 0.09 1.6e-07 0.14 0.12 0.13 0.12 9.3e-08 5.7e-07 2.6e-07 3.4e-07
3 BLA intron excision ratio chr6:25421678:25421932 0.1 0.07 1.9e-05 0.08 0.09 0.07 0.08 6.9e-05 2.6e-05 1.5e-04 6.1e-05
4 Brain alternative polyA ENSRNOT00000009565 0.07 0.05 5.6e-08 0.07 0.08 0.06 0.07 9.2e-07 1.3e-07 2.7e-06 6.5e-07
5 Brain alternative polyA ENSRNOT00000114417 0.07 0.05 6.5e-08 0.06 0.08 0.06 0.07 1.1e-06 1.5e-07 3.9e-06 1.0e-06
6 Brain alternative polyA ENSRNOT00000009565 0.07 0.05 6.2e-08 0.07 0.08 0.06 0.07 8.9e-07 1.4e-07 2.4e-06 5.6e-07
7 Brain alternative polyA ENSRNOT00000114417 0.07 0.05 8.3e-08 0.06 0.07 0.06 0.06 1.2e-06 1.9e-07 4.2e-06 1.1e-06
8 Brain gene expression ENSRNOG00000007141 0.06 0.04 1.1e-05 0.04 0.04 0.03 0.03 1.1e-04 1.1e-04 5.9e-04 7.7e-04
9 Liver intron excision ratio chr6:25420313:25420487 0.04 0.04 5.1e-04 0.02 0.02 0.02 0.02 9.5e-04 1.3e-03 1.1e-03 1.3e-03
10 Liver intron excision ratio chr6:25420567:25420675 0.04 0.04 4.5e-04 0.02 0.02 0.02 0.02 9.1e-04 1.5e-03 1.0e-03 1.5e-03
11 Liver mRNA stability ENSRNOG00000007141 0.04 0.04 3.3e-04 0.03 0.03 0.03 0.03 5.0e-04 7.3e-04 6.3e-04 5.0e-04
12 NAcc gene expression ENSRNOG00000007141 0.12 0.1 8.4e-05 0.06 0.03 0.04 0.05 5.2e-05 1.4e-03 9.7e-04 1.3e-04
13 OFC gene expression ENSRNOG00000007141 0.19 0.17 1.7e-03 0.12 0.12 0.15 0.14 1.1e-03 9.7e-04 2.3e-04 3.7e-04
14 PL gene expression ENSRNOG00000007141 0.09 0.07 3.1e-07 0.08 0.09 0.07 0.08 8.1e-07 4.5e-07 3.1e-06 1.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.51.53.6-0.9-0.91.41.3-1.41.4-1.4-1.1-0.90.91.1-1.2-1.9-1.2
BMI without tail0.20.30.5-0.5-0.60.50.5-0.50.5-0.5-0.7-0.50.50.7-0.4-0.6-0.5
Body weight1.98.110.0-2.7-2.82.92.9-2.92.9-2.9-3.0-2.72.73.0-2.5-3.2-2.8
Epididymis fat weight15.135.237.8-5.9-6.15.95.9-5.95.9-5.9-6.1-5.95.96.1-5.5-6.0-5.9
Glucose0.20.30.3-0.5-0.50.50.5-0.50.5-0.5-0.5-0.50.50.5-0.5-0.6-0.5
Heart weight8.512.115.5-3.4-3.43.63.6-3.53.6-3.5-3.3-3.43.43.4-3.9-3.4-3.5
Left kidney weight0.00.00.1-0.2-0.20.10.1-0.10.1-0.10.0-0.20.2-0.0-0.20.1-0.1
Right kidney weight1.23.43.7-1.9-1.91.91.9-1.91.9-1.9-1.7-1.91.91.7-1.9-1.8-1.9
Tail length0.10.30.7-0.5-0.80.30.4-0.40.4-0.4-0.8-0.50.50.8-0.20.0-0.5
Length with tail1.55.36.9-2.3-2.52.22.2-2.22.2-2.2-2.6-2.32.32.6-2.0-2.0-2.3
Length without tail0.71.62.0-1.2-1.21.31.3-1.31.3-1.3-1.3-1.21.21.3-1.2-1.4-1.3
Liver weight, left1.32.02.2-1.4-1.41.51.5-1.51.5-1.5-1.4-1.41.41.4-1.3-1.4-1.4
Liver weight, right8.914.815.5-3.8-3.83.93.9-3.93.9-3.9-3.8-3.83.83.8-3.9-3.9-3.9
Parametrial fat weight6.111.913.6-3.2-3.13.63.6-3.63.6-3.6-3.4-3.23.23.4-3.5-3.7-3.5
Retroperitoneal fat weight22.273.484.3-8.5-8.48.78.6-8.78.7-8.7-8.3-8.58.58.3-8.2-9.2-8.6
Intraocular pressure6.28.89.4-2.9-2.93.03.0-3.03.0-3.0-2.9-2.92.92.9-2.9-3.1-3.0
Extensor digitorum longus weight4.317.218.14.24.3-4.1-4.14.1-4.14.14.24.2-4.2-4.24.23.94.2
Soleus weight4.111.912.73.53.6-3.4-3.43.4-3.43.43.53.5-3.5-3.53.43.53.4
Tibialis anterior weight3.311.512.83.63.6-3.3-3.33.3-3.33.33.53.6-3.6-3.53.33.03.4
Tibia length2.26.36.4-2.5-2.52.52.5-2.52.5-2.5-2.5-2.52.52.5-2.5-2.4-2.5
Number of licking bursts0.00.00.10.20.30.20.2-0.20.2-0.20.30.2-0.2-0.30.2-0.30.0
Food consumed during 24 hour testing period0.20.30.40.60.6-0.4-0.30.3-0.30.30.60.6-0.6-0.60.60.30.5
Times rat made contact with spout1.82.12.51.51.5-1.4-1.41.3-1.31.31.51.5-1.5-1.51.61.41.4
Mean time between licks in bursts2.63.73.9-1.9-1.92.02.0-2.02.0-2.0-1.9-1.91.91.9-1.9-1.8-1.9
Mean num. licks in bursts0.20.30.70.40.4-0.6-0.60.6-0.60.60.40.4-0.4-0.40.50.80.5
Std. dev. time between licks in bursts0.10.10.2-0.2-0.20.40.5-0.50.5-0.5-0.2-0.20.20.2-0.1-0.4-0.3
Water consumed over 24 hours1.51.82.31.51.5-1.1-1.11.1-1.11.11.51.5-1.5-1.51.51.01.3
Indifference point 0 sec0.40.61.3-0.8-0.70.80.8-0.80.8-0.8-0.7-0.80.80.7-0.7-1.2-0.8
Indifference point AUC2.42.93.61.91.9-1.6-1.61.5-1.51.51.71.9-1.9-1.71.71.41.7
Indifference point function ln k0.00.00.2-0.2-0.1-0.1-0.00.1-0.10.1-0.1-0.20.20.10.00.4-0.0
Indifference point function log k0.00.00.2-0.2-0.1-0.1-0.00.1-0.10.1-0.1-0.20.20.10.00.4-0.0
Delay discounting total patch changes 0 sec0.30.51.2-0.7-0.60.80.7-0.70.7-0.7-0.6-0.70.70.6-0.6-1.1-0.7
Delay discounting total patch changes 12 sec0.81.11.8-0.9-1.01.11.0-1.11.1-1.1-0.9-0.90.90.9-1.0-1.3-1.0
Delay discounting total patch changes 18 sec0.00.00.40.00.10.20.2-0.20.2-0.2-0.10.0-0.00.1-0.0-0.6-0.1
Delay discounting total patch changes 24 sec0.70.91.4-0.9-0.81.01.0-1.01.0-1.0-0.9-0.90.90.9-0.9-1.2-0.9
Delay discounting total patch changes 6 sec0.10.10.5-0.1-0.20.30.3-0.30.3-0.3-0.1-0.10.10.1-0.2-0.7-0.3
Delay discounting time to switch 0 sec0.00.10.2-0.3-0.30.20.2-0.20.2-0.2-0.1-0.30.30.1-0.3-0.5-0.2
Delay discounting water rate 0 sec0.10.10.40.20.2-0.3-0.30.3-0.30.3-0.00.2-0.20.00.40.60.2
Delay discounting water rate 12 sec1.52.32.8-1.6-1.61.41.4-1.41.4-1.4-1.7-1.61.61.7-1.5-1.2-1.5
Delay discounting water rate 18 sec0.50.70.9-1.0-1.00.70.7-0.70.7-0.7-0.9-1.01.00.9-0.9-0.4-0.8
Delay discounting water rate 24 sec2.23.04.3-1.8-1.91.61.6-1.61.6-1.6-2.1-1.81.82.1-1.5-1.4-1.7
Delay discounting water rate 6 sec1.11.72.2-1.3-1.31.21.2-1.21.2-1.2-1.5-1.31.31.5-1.4-0.7-1.3
Locomotor activity0.40.71.2-0.8-0.70.80.9-0.90.9-0.9-0.7-0.80.80.7-0.6-1.1-0.8
Locomotor testing distance0.00.00.10.20.2-0.1-0.10.1-0.10.10.20.2-0.2-0.20.3-0.30.2
Locomotor testing rearing0.60.91.70.90.8-1.1-1.11.1-1.11.10.80.9-0.9-0.81.30.61.0
Light reinforcement 14.07.39.42.92.9-2.5-2.52.5-2.52.53.12.9-2.9-3.12.52.02.7
Light reinforcement 23.95.17.12.42.4-2.1-2.12.1-2.12.12.72.4-2.4-2.71.82.02.3
Reaction time number correct0.50.81.00.91.0-0.8-0.80.8-0.80.80.80.9-0.9-0.80.80.90.9
Reaction time mean minus median0.00.00.0-0.1-0.1-0.1-0.10.1-0.10.1-0.1-0.10.10.10.00.1-0.0
Reaction time mean minus median AUC0.10.10.1-0.3-0.30.20.2-0.20.2-0.2-0.3-0.30.30.3-0.3-0.2-0.2
Reaction time num false alarms0.10.10.70.20.30.20.2-0.20.2-0.20.40.2-0.2-0.4-0.0-0.8-0.0
Reaction time num false alarms AUC0.10.10.50.30.30.20.1-0.20.1-0.20.50.3-0.3-0.50.0-0.70.0
Reaction time trials correct on left0.50.81.00.91.0-0.8-0.80.8-0.80.80.80.9-0.9-0.80.80.90.9
Reaction time trials on left0.60.81.11.01.0-0.8-0.80.8-0.80.80.91.0-1.0-0.90.90.90.9
Reaction time mean1.11.51.9-1.3-1.31.21.2-1.11.2-1.2-1.3-1.31.31.3-1.4-0.7-1.2
Reaction time mean AUC0.91.31.7-1.2-1.11.01.0-1.01.0-1.0-1.2-1.21.21.2-1.3-0.7-1.1
Median of all reaction times1.21.62.2-1.3-1.21.21.2-1.21.2-1.2-1.3-1.31.31.3-1.5-0.7-1.3
Reaction time omissions0.10.10.10.30.3-0.2-0.20.2-0.20.20.40.3-0.3-0.40.30.10.3
Reaction time false alarm rate0.20.31.3-0.3-0.20.60.6-0.60.6-0.6-0.0-0.30.30.0-0.4-1.1-0.4
Reaction time premature initiation rate0.20.30.4-0.6-0.60.50.5-0.50.5-0.5-0.4-0.60.60.4-0.5-0.6-0.5
Reaction time premature initiations0.00.00.0-0.0-0.00.00.0-0.00.0-0.00.0-0.00.0-0.00.0-0.1-0.0
Std. dev. reaction times0.30.40.5-0.7-0.70.60.6-0.60.6-0.6-0.7-0.70.70.7-0.6-0.4-0.6
Reaction time trials completed0.60.81.11.01.0-0.8-0.80.8-0.80.80.91.0-1.0-0.90.90.90.9
Reaction time trials AUC0.71.01.31.11.1-1.0-1.01.0-1.01.01.01.1-1.1-1.01.01.01.0
Social response proportion0.20.20.4-0.5-0.60.40.4-0.40.4-0.4-0.6-0.50.50.6-0.2-0.2-0.5
Social responses0.00.00.1-0.2-0.20.20.2-0.30.2-0.2-0.2-0.20.20.20.2-0.3-0.2
Social time0.20.20.4-0.5-0.60.40.4-0.40.4-0.4-0.6-0.50.50.6-0.2-0.2-0.5
Conditioned locomotion3.23.84.81.91.9-2.0-2.02.0-2.02.01.81.9-1.9-1.82.02.22.0
Cocaine response after cond. corrected0.80.81.21.01.0-0.8-0.80.8-0.80.81.11.0-1.0-1.10.90.90.9
Cocaine response after cond. not corrected1.71.92.31.41.5-1.3-1.31.3-1.31.31.51.4-1.4-1.51.31.41.4
Cocaine response before conditioning1.41.62.31.21.2-1.3-1.41.4-1.41.41.21.2-1.2-1.21.11.51.3
Saline control response0.81.11.21.01.1-1.0-1.01.0-1.01.01.01.0-1.0-1.01.11.11.0
Condit. Reinf. active minus inactive responses3.74.64.92.12.1-2.2-2.22.2-2.22.22.12.1-2.1-2.12.21.92.1
Condit. Reinf. active-inactive response ratio1.01.01.11.01.0-1.0-1.01.0-1.01.01.01.0-1.0-1.00.91.01.0
Condit. Reinf. active responses3.04.14.52.02.0-2.1-2.12.1-2.12.12.02.0-2.0-2.02.11.82.0
Condit. Reinf. inactive responses1.51.92.21.41.4-1.4-1.41.4-1.41.41.41.4-1.4-1.41.51.21.4
Condit. Reinf. lever presses1.92.72.91.61.6-1.6-1.61.6-1.61.61.61.6-1.6-1.61.71.71.6
Condit. Reinf. lever reinforcers received2.63.74.11.91.8-2.0-2.02.0-2.02.01.91.9-1.9-1.92.01.71.9
Pavlov. Cond. lever latency1.82.42.8-1.5-1.51.51.5-1.51.5-1.5-1.6-1.51.51.6-1.7-1.6-1.5
Pavlov. Cond. magazine entry latency0.40.40.50.70.7-0.6-0.60.6-0.60.60.70.7-0.7-0.70.60.60.7
Pavlov. Cond. change in total contacts0.60.81.10.90.9-0.8-0.80.8-0.80.80.90.9-0.9-0.91.01.00.9
Pavlov. Cond. index score1.21.61.81.31.3-1.2-1.21.2-1.21.21.31.3-1.3-1.31.41.31.2
Pavlov. Cond. latency score1.21.51.81.31.3-1.2-1.21.2-1.21.21.31.3-1.3-1.31.31.31.2
Pavlov. Cond. lever contacts0.81.11.41.11.0-1.0-1.01.0-1.01.01.11.1-1.1-1.11.21.11.1
Pavlov. Cond. magazine entry number0.10.20.2-0.5-0.50.30.3-0.30.3-0.3-0.5-0.50.50.5-0.5-0.4-0.4
Pavlov. Cond. intertrial magazine entries3.84.95.2-2.3-2.32.22.2-2.22.2-2.2-2.3-2.32.32.3-2.1-2.3-2.2
Pavlov. Cond. lever-magazine prob. diff.0.91.11.41.11.1-1.0-1.01.0-1.01.01.11.1-1.1-1.11.21.11.0
Pavlov. Cond. response bias1.62.32.51.51.5-1.4-1.41.4-1.41.41.61.5-1.5-1.61.51.61.5
Conditioned reinforcement - actives1.71.72.81.21.2-1.4-1.41.4-1.41.40.81.2-1.2-0.81.41.71.3
Conditioned reinforcement - inactives3.74.15.91.82.0-2.0-2.02.0-2.02.02.41.8-1.8-2.41.82.12.0
Conditioned locomotion0.40.51.50.30.3-0.9-0.90.9-0.90.90.10.3-0.3-0.11.11.20.7
Intermittent access intake day 1-15 change0.40.40.70.80.5-0.6-0.50.5-0.50.50.30.8-0.8-0.30.40.80.6
Intermittent access intake escalation0.10.10.30.50.3-0.3-0.30.3-0.30.30.10.5-0.5-0.10.20.50.3
Intermittent access intake escalation 20.10.10.30.1-0.10.30.3-0.30.3-0.3-0.10.1-0.10.1-0.5-0.3-0.2
Intermitt. access day 1 inactive lever presses0.30.30.90.30.7-0.4-0.50.5-0.50.50.90.3-0.3-0.90.30.30.5
Intermitt. access day 15 inactive lever presses9.910.913.43.33.7-3.2-3.23.2-3.23.23.63.3-3.3-3.63.02.83.3
Intermitt. access escalation Index0.20.10.6-0.0-0.10.40.4-0.50.4-0.5-0.2-0.00.00.2-0.4-0.8-0.3
Intermittent access day 1 total infusions6.06.88.32.42.5-2.6-2.62.6-2.62.62.92.4-2.4-2.92.52.62.6
Intermittent access day 15 total infusions3.23.64.01.91.8-1.9-1.91.9-1.91.91.91.9-1.9-1.91.72.01.9
Intermittent access terminal intake (last 3 days)2.83.03.81.71.6-1.7-1.71.7-1.71.71.81.7-1.7-1.81.61.91.7
Intermittent access total infusions2.62.93.81.51.5-1.8-1.81.8-1.81.81.71.5-1.5-1.71.82.01.7
Intermittent access day 1 locomotion2.52.63.21.51.6-1.6-1.61.6-1.61.61.81.5-1.5-1.81.51.71.6
Intermittent access day 15 total locomotion0.91.01.40.91.0-1.0-1.01.0-1.01.01.10.9-0.9-1.11.11.21.0
Intermittent access total locomotion0.40.50.80.50.5-0.7-0.70.7-0.70.70.70.5-0.5-0.70.90.90.7
Intermittent access standard deviation0.30.30.50.40.4-0.6-0.60.6-0.60.60.70.4-0.4-0.70.50.40.5
Cocaine induced anxiety0.50.60.90.90.8-0.7-0.70.7-0.70.70.90.9-0.9-0.90.70.70.8
Post-drug Anxiety0.70.81.4-0.7-0.71.01.0-1.01.0-1.0-0.7-0.70.70.7-1.2-1.0-0.9
Baseline Anxiety1.92.02.4-1.4-1.31.41.4-1.41.4-1.4-1.5-1.41.41.5-1.5-1.4-1.4
Lifetime Intake3.74.15.01.81.9-2.1-2.12.1-2.12.12.11.8-1.8-2.12.12.22.0
Incentive Sensitization - Responses0.00.00.1-0.1-0.30.10.1-0.10.1-0.1-0.0-0.10.10.0-0.20.1-0.1
Incentive Sensitization - Breakpoint0.10.10.2-0.2-0.40.20.3-0.30.3-0.3-0.2-0.20.20.2-0.4-0.1-0.3
Progressive ratio test 1 active lever presses2.02.02.41.11.2-1.5-1.51.5-1.51.51.51.1-1.1-1.51.51.61.4
Progressive ratio test 1 breakpoint1.71.82.11.11.1-1.4-1.41.4-1.41.41.41.1-1.1-1.41.41.41.3
Progressive ratio test 1 inactive lever presses5.25.66.22.12.2-2.5-2.52.5-2.52.52.42.1-2.1-2.42.42.42.4
Progressive ratio test 2 active lever presses0.20.20.40.30.2-0.5-0.50.5-0.50.50.40.3-0.3-0.40.50.70.4
Progressive ratio test 2 breakpoint0.20.30.50.30.2-0.6-0.60.6-0.60.60.50.3-0.3-0.50.60.70.5
Progressive ratio test 2 inactive lever presses2.93.44.11.71.7-1.9-1.91.9-1.91.92.01.7-1.7-2.01.71.91.8
Total sessions with >9 infusions2.83.04.01.31.6-1.9-1.92.0-1.91.91.61.3-1.3-1.62.01.91.8
Short access day 1 total inactive lever presses5.86.58.92.42.7-2.5-2.52.5-2.52.53.02.4-2.4-3.02.22.42.5
Short access day 10 total inactive lever presses1.21.32.31.11.3-1.0-1.11.0-1.11.01.51.1-1.1-1.50.90.61.1
Short access day 1 total infusions5.65.96.72.22.4-2.6-2.62.6-2.62.62.42.2-2.2-2.42.62.42.5
Short access day 10 total infusions4.65.06.32.02.2-2.3-2.32.3-2.32.32.32.0-2.0-2.32.32.52.2
Short access total infusions3.53.94.61.71.8-2.1-2.12.1-2.12.11.91.7-1.7-1.92.12.22.0
Short access day 1 locomotion7.47.98.82.62.5-2.9-2.92.9-2.92.92.72.6-2.6-2.73.02.92.8
Short access day 10 total locomotion1.01.11.50.91.0-1.0-1.11.1-1.11.11.20.9-0.9-1.20.91.21.0
Short access total locomotion0.90.91.60.70.8-1.0-1.01.0-1.01.01.00.7-0.7-1.00.91.20.9
Compulsive drug intake0.80.81.7-0.7-0.51.01.0-1.01.0-1.0-0.8-0.70.70.8-1.0-1.3-0.8
One hour access (0.3 mA shock)2.12.42.51.61.6-1.6-1.51.5-1.51.51.61.6-1.6-1.61.61.51.6
One hour access (shock baseline)2.32.73.81.41.4-1.7-1.71.7-1.71.71.51.4-1.4-1.51.91.91.6
Number of responses in last shaping day0.70.71.10.70.7-0.9-0.90.9-0.90.90.60.7-0.7-0.61.01.00.8
Context. condit. distance diff. score0.00.00.0-0.1-0.10.00.0-0.00.0-0.0-0.0-0.10.10.1-0.10.0-0.1
Locomotion velocity, session 10.00.00.10.00.00.20.2-0.20.2-0.20.10.0-0.0-0.1-0.1-0.4-0.1
Locomotion distance, session 11.82.33.21.71.7-1.3-1.31.3-1.31.31.81.7-1.7-1.71.51.21.5
Locomotion velocity, session 20.20.30.3-0.5-0.50.50.6-0.50.6-0.5-0.5-0.50.50.5-0.5-0.4-0.5
Locomotion distance, session 20.00.00.00.10.10.00.0-0.00.0-0.00.10.1-0.1-0.10.1-0.20.0
Locomotion velocity, session 30.60.70.80.90.9-0.9-0.90.9-0.90.90.80.9-0.9-0.80.70.60.9
Locomotion distance, session 30.80.91.11.11.1-0.9-0.90.9-0.90.91.11.1-1.1-1.10.90.51.0
Stereotopy head waving bouts, day 32.02.42.81.51.5-1.6-1.61.6-1.61.61.41.5-1.5-1.41.61.71.5
Stereotopy head waving duration, day 30.20.20.40.30.3-0.5-0.50.5-0.50.50.30.3-0.3-0.30.50.60.4
Locomotion velocity, session 71.11.21.61.21.2-1.0-1.01.0-1.01.01.21.2-1.2-1.21.10.91.1
Locomotion distance, session 70.10.10.20.40.4-0.1-0.10.1-0.10.10.40.4-0.4-0.40.4-0.30.2
Stereotopy head waving bouts, day 70.00.00.0-0.1-0.10.10.1-0.10.1-0.1-0.2-0.10.10.2-0.20.0-0.1
Stereotopy head waving duration, day 70.40.40.70.60.6-0.7-0.70.7-0.70.70.50.6-0.6-0.60.70.80.6
Locomotion velocity, session 80.30.40.60.50.5-0.6-0.60.6-0.60.60.50.5-0.5-0.60.80.80.6
Locomotion distance, session 80.30.50.70.80.8-0.6-0.60.6-0.60.60.80.8-0.8-0.80.70.70.7
Degree of sensitization distance0.80.80.9-0.9-0.90.90.9-1.01.0-1.0-0.9-0.90.90.9-0.8-0.9-0.9
Degree of sensitization stereotypy0.20.20.3-0.5-0.50.50.5-0.50.5-0.5-0.5-0.50.50.5-0.5-0.4-0.5
Condit. Reinf. active minus inactive responses0.80.91.3-0.9-0.81.01.0-1.01.0-1.0-0.9-0.90.90.9-1.0-1.1-0.9
Condit. Reinf. active-inactive response ratio0.91.01.3-1.0-0.91.00.9-0.90.9-0.9-1.0-1.01.01.0-1.1-1.1-1.0
Condit. Reinf. active responses0.10.10.20.40.4-0.2-0.20.2-0.20.20.40.4-0.4-0.40.30.10.3
Condit. Reinf. inactive responses1.61.92.21.51.5-1.3-1.31.3-1.31.31.51.5-1.5-1.51.51.31.4
Incentive salience index mean0.00.00.00.10.10.00.0-0.00.0-0.00.10.1-0.1-0.1-0.0-0.20.0
Condit. Reinf. lever presses0.50.60.80.80.9-0.7-0.70.7-0.70.70.90.8-0.8-0.90.70.80.8
Time in familiar zone, hab. session 10.70.70.9-0.8-0.80.80.9-0.90.9-0.9-0.8-0.80.80.8-0.7-0.9-0.8
Time in novel zone, hab. session 10.60.60.8-0.9-0.90.70.6-0.60.6-0.6-0.9-0.90.90.9-0.8-0.8-0.8
Total zone transitions, hab. session 10.10.10.20.40.4-0.3-0.30.3-0.30.30.30.4-0.4-0.40.50.40.3
Total locomotion distance, hab. session 10.20.30.60.50.5-0.5-0.50.5-0.50.50.50.5-0.5-0.50.70.80.5
Locomotion velocity, hab. session 11.11.62.21.31.3-1.2-1.21.2-1.21.21.31.3-1.3-1.31.31.51.3
Time in familiar zone, hab. session 20.00.00.00.20.2-0.0-0.00.0-0.00.00.10.2-0.2-0.10.2-0.10.1
Time in novel zone, hab. session 20.60.60.7-0.9-0.90.70.7-0.70.7-0.7-0.8-0.90.90.8-0.8-0.7-0.8
Total zone transitions, hab. session 20.10.10.20.30.3-0.1-0.10.1-0.10.10.40.3-0.3-0.30.5-0.10.2
Total locomotion distance, hab. session 20.20.20.50.50.5-0.3-0.30.3-0.30.30.60.5-0.5-0.60.70.20.4
Locomotion velocity, hab. session 20.30.50.70.80.8-0.5-0.50.5-0.50.50.80.8-0.8-0.80.90.40.7
Novel to familiar place preference ratio1.11.21.4-1.1-1.11.11.1-1.11.1-1.1-1.0-1.11.11.1-1.2-1.0-1.1
Novelty place preference1.81.92.1-1.4-1.41.41.3-1.31.3-1.3-1.3-1.41.41.4-1.4-1.3-1.4
Time in novel zone, NPP test2.02.12.4-1.5-1.51.41.4-1.41.4-1.4-1.5-1.51.51.5-1.6-1.4-1.5
Total zone transitions, NPP test1.42.02.21.51.5-1.3-1.31.3-1.31.31.41.5-1.5-1.41.41.31.4
Total locomotion distance, NPP test2.02.72.91.71.7-1.6-1.61.6-1.61.61.71.7-1.7-1.71.71.51.7
Locomotion velocity, NPP test3.24.64.92.22.2-2.1-2.12.1-2.12.12.22.2-2.2-2.22.22.02.1
Pavlov. Cond. lever latency1.72.22.8-1.6-1.61.41.4-1.41.4-1.4-1.7-1.61.61.7-1.4-1.2-1.5
Pavlov. Cond. magazine entry latency0.00.00.00.20.2-0.1-0.10.1-0.10.10.20.2-0.2-0.20.1-0.10.1
Pavlov. Cond. change in total contacts0.00.00.10.20.2-0.1-0.10.1-0.10.10.30.2-0.2-0.30.10.00.2
Pavlov. Cond. index score0.70.91.21.11.1-0.8-0.80.8-0.80.81.11.1-1.1-1.10.90.60.9
Pavlov. Cond. latency score0.70.81.21.11.1-0.8-0.80.8-0.80.81.11.1-1.1-1.10.80.60.9
Pavlov. Cond. lever contacts1.01.21.51.21.2-1.0-1.01.0-1.01.01.21.2-1.2-1.21.00.91.1
Pavlov. Cond. magazine entry number0.40.50.7-0.8-0.90.60.7-0.60.6-0.6-0.8-0.80.80.8-0.7-0.4-0.7
Pavlov. Cond. intertrial magazine entries1.21.52.01.11.1-1.3-1.31.3-1.31.31.21.1-1.1-1.21.11.41.2
Pavlov. Cond. lever-magazine prob. diff.1.51.82.21.51.5-1.3-1.31.2-1.31.31.51.5-1.5-1.51.31.11.4
Pavlov. Cond. response bias1.51.82.11.41.4-1.3-1.31.3-1.31.31.41.4-1.4-1.41.21.21.4
Bone: apparent density5.38.89.63.03.1-2.9-2.92.9-2.92.93.13.0-3.0-3.13.02.93.0
Bone surface2.74.75.82.32.4-2.0-2.02.0-2.02.02.42.3-2.3-2.42.31.92.2
Bone volume3.05.05.82.32.4-2.1-2.12.1-2.12.12.42.3-2.3-2.42.32.22.2
Bone: connectivity density4.97.68.62.92.9-2.7-2.72.6-2.62.62.92.9-2.9-2.92.82.52.8
Bone: cortical apparent density0.30.40.50.60.6-0.5-0.50.5-0.50.50.70.6-0.6-0.70.60.60.6
Bone: cortical area0.30.40.70.70.8-0.5-0.40.4-0.40.40.80.7-0.7-0.80.70.40.6
Bone: cortical porosity1.71.92.71.21.2-1.5-1.51.5-1.51.51.21.2-1.2-1.21.41.61.4
Bone: cortical porosity1.51.62.41.21.1-1.3-1.31.3-1.31.31.11.2-1.2-1.11.21.51.3
Bone: cortical thickness0.00.10.2-0.1-0.00.40.4-0.40.4-0.4-0.1-0.10.10.1-0.2-0.3-0.2
Bone: cortical thickness1.51.72.01.41.4-1.2-1.21.2-1.21.21.31.4-1.4-1.31.41.21.3
Bone: cortical tissue density0.20.20.30.50.5-0.4-0.40.4-0.40.40.60.5-0.5-0.60.50.50.5
Bone: elastic displacement0.80.91.40.80.8-1.0-1.01.1-1.11.10.80.8-0.8-0.80.91.20.9
Bone: elastic work0.91.21.41.11.1-1.1-1.11.1-1.11.11.11.1-1.1-1.11.11.21.1
Bone: endosteal estimation0.40.91.31.01.0-0.9-0.80.8-0.80.81.01.0-1.0-1.01.10.60.9
Bone: endosteal perimeter0.10.30.40.60.6-0.4-0.40.4-0.40.40.60.6-0.6-0.60.60.30.5
Bone: final force0.10.20.40.50.6-0.3-0.30.3-0.30.30.50.5-0.5-0.50.60.30.4
Bone: final moment0.10.20.40.50.6-0.4-0.30.3-0.30.30.60.5-0.5-0.50.70.40.5
Bone: marrow area0.40.91.31.01.0-0.9-0.90.9-0.90.91.01.0-1.0-1.01.10.71.0
Bone: maximum diameter0.81.41.91.31.4-1.0-1.01.0-1.01.01.31.3-1.3-1.31.30.91.2
Bone: maximum force0.00.00.10.20.3-0.1-0.10.1-0.10.10.20.2-0.2-0.20.40.10.2
Bone: maximum moment0.00.10.20.30.4-0.2-0.20.2-0.20.20.30.3-0.3-0.30.50.20.3
Bone: minimum diameter0.10.20.6-0.3-0.20.50.5-0.50.5-0.5-0.3-0.30.30.3-0.1-0.7-0.4
Bone: periosteal estimation0.61.21.61.21.3-0.9-0.90.9-0.90.91.21.2-1.2-1.21.20.81.1
Bone: periosteal perimeter0.20.30.40.60.7-0.4-0.40.3-0.40.30.60.6-0.6-0.60.60.30.5
Bone: post-yield work0.50.71.00.80.8-0.9-0.90.9-0.90.90.70.8-0.8-0.71.01.00.9
Bone: stiffness0.00.00.1-0.0-0.00.20.2-0.20.2-0.2-0.1-0.00.00.10.1-0.2-0.1
Bone: tissue strength1.01.01.0-1.0-1.01.01.0-1.01.0-1.0-1.0-1.01.01.0-1.0-0.8-1.0
Bone: trabecular number4.26.57.12.62.7-2.5-2.52.5-2.52.52.72.6-2.6-2.72.52.52.6
Bone: trabecular spacing3.64.65.5-2.2-2.32.12.1-2.02.1-2.0-2.2-2.22.22.2-2.4-1.9-2.2
Bone: trabecular thickness0.91.11.71.01.1-1.0-1.01.0-1.01.01.01.0-1.0-1.01.31.11.0
Bone: trabecular tissue density0.20.30.50.50.5-0.6-0.60.6-0.60.60.50.5-0.5-0.50.50.70.6
Breakpoint value in progressive ratio session1.01.12.01.00.8-1.1-1.11.1-1.11.10.91.0-1.0-0.91.41.01.0
Distance traveled before self-admin0.00.00.10.20.1-0.1-0.10.1-0.10.10.10.2-0.2-0.10.10.40.1
Distance traveled after self-admin0.80.91.0-0.7-0.81.01.0-1.01.0-1.0-1.0-0.70.71.0-1.0-0.9-0.9
Delta time in closed arm before/after self-admin0.10.10.3-0.1-0.20.30.3-0.30.3-0.3-0.1-0.10.10.1-0.2-0.5-0.2
Delta time in open arm before/after self-admin0.30.30.40.50.5-0.6-0.60.6-0.60.60.60.5-0.5-0.60.60.40.6
Diff in mean of infusions in LGA sessions0.20.20.50.50.3-0.5-0.50.4-0.50.40.40.5-0.5-0.40.70.50.5
Extinction: sum of active levers before priming0.30.30.40.60.4-0.5-0.50.5-0.50.50.60.6-0.6-0.60.60.40.6
Active lever presses in extinction session 60.60.51.20.60.4-0.9-0.80.9-0.90.90.50.6-0.6-0.51.10.70.7
Delta distance traveled before/after self-admin1.31.41.8-1.1-1.01.21.2-1.21.2-1.2-1.2-1.11.11.2-1.3-1.3-1.2
Delta ambulatory time before/after self-admin0.20.20.3-0.3-0.30.50.5-0.50.5-0.5-0.5-0.30.30.5-0.5-0.6-0.4
Time in closed arm before self-admin0.50.50.8-0.9-0.80.70.7-0.70.7-0.7-0.8-0.90.90.8-0.4-0.7-0.7
Time in closed arm after self-admin1.61.62.0-1.4-1.31.21.2-1.21.2-1.2-1.4-1.41.41.4-0.9-1.3-1.2
Time in open arm before self-admin0.00.00.10.20.00.10.1-0.10.1-0.10.20.2-0.2-0.2-0.40.1-0.0
Time in open arm after self-admin1.92.13.01.61.6-1.3-1.31.3-1.31.31.71.6-1.6-1.71.01.21.4
Sum of active levers in priming session hrs 5-60.60.61.20.90.9-0.6-0.60.6-0.60.61.10.9-0.9-1.10.60.30.8
Time to tail flick, vehicle, before self-admin2.52.53.2-1.7-1.81.51.5-1.51.5-1.5-1.8-1.71.71.8-1.5-1.4-1.6
Time to tail flick, vehicle, after self-admin4.44.75.4-2.3-2.22.12.1-2.12.1-2.1-2.3-2.32.32.3-1.8-2.0-2.2
Time to tail flick, test, before self-admin0.60.60.70.70.6-0.8-0.80.8-0.80.80.80.7-0.7-0.80.80.90.8
Time to tail flick, test, after self-admin0.10.10.2-0.4-0.40.20.2-0.20.2-0.2-0.2-0.40.40.2-0.1-0.0-0.2
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.2-0.00.20.2-0.20.2-0.2-0.0-0.20.20.10.1-0.3-0.1
Delta time to tail flick, test, before/after SA0.40.40.50.60.6-0.6-0.60.6-0.60.60.60.6-0.6-0.60.50.70.6
Ambulatory time before self-admin0.10.10.20.40.3-0.3-0.30.3-0.30.30.30.4-0.4-0.30.30.50.3
Ambulatory time after self-admin0.40.50.8-0.5-0.60.70.8-0.70.8-0.7-0.8-0.50.50.8-0.9-0.6-0.7
Total heroin consumption2.63.13.51.91.7-1.7-1.71.7-1.71.71.81.9-1.9-1.81.81.61.8
Area under the delay curve0.00.00.0-0.1-0.10.10.1-0.10.1-0.1-0.1-0.10.10.10.10.1-0.1
Delay disc. indifference point, 0s delay3.53.84.1-1.9-1.92.02.0-2.02.0-2.0-1.9-1.91.91.9-1.9-1.7-2.0
Delay disc. indifference point, 16s delay0.10.10.10.30.3-0.2-0.20.2-0.20.20.30.3-0.3-0.30.20.30.2
Delay disc. indifference point, 2s delay0.30.30.4-0.5-0.50.60.6-0.60.6-0.6-0.5-0.50.50.5-0.6-0.4-0.6
Delay disc. indifference point, 24s delay0.80.71.50.80.8-0.9-0.90.9-0.90.90.80.8-0.8-0.81.01.20.8
Delay disc. indifference point, 4s delay0.00.00.00.10.10.10.1-0.10.1-0.10.10.1-0.1-0.1-0.0-0.0-0.0
Delay disc. indifference point, 8s delay0.00.00.10.00.0-0.1-0.00.0-0.00.00.00.0-0.0-0.00.20.30.0
Delay discount exponential model param0.10.10.1-0.2-0.20.20.2-0.20.2-0.2-0.2-0.20.20.2-0.3-0.4-0.2
Delay discount hyperbolic model param0.10.10.1-0.3-0.30.20.2-0.20.2-0.2-0.3-0.30.30.3-0.3-0.4-0.3
Fecal boli incidents, locomotor time 10.30.40.50.60.6-0.7-0.70.7-0.70.70.50.6-0.6-0.50.40.60.6
Change in fecal boli incidents, locomotor task4.84.64.6-2.2-2.22.12.1-2.22.1-2.2-2.1-2.22.22.1-2.0-2.1-2.1
Time >=10cm from walls, locomotor time 10.10.10.2-0.4-0.40.30.3-0.20.3-0.3-0.5-0.40.40.4-0.2-0.1-0.3
Bouts of movement, locomotor time 12.12.33.21.61.6-1.4-1.51.4-1.51.51.51.6-1.6-1.61.81.31.5
Total resting periods, locomotor time 12.52.83.61.81.8-1.6-1.61.6-1.61.61.71.8-1.8-1.71.91.41.7
Rest time, locomotor task time 10.10.10.20.20.2-0.3-0.40.4-0.40.40.30.2-0.2-0.30.40.30.3
Distance moved, locomotor task time 11.31.41.6-1.1-1.11.21.2-1.21.2-1.2-1.2-1.11.11.2-1.3-1.0-1.2
Vertical activity count, locomotor time 10.60.60.8-0.7-0.70.80.8-0.80.8-0.8-0.8-0.70.70.8-0.9-0.7-0.8
Time >=10cm from walls, locomotor time 20.20.20.80.30.3-0.5-0.50.5-0.50.50.30.3-0.3-0.30.70.90.5
Bouts of movement, locomotor time 20.10.10.2-0.3-0.30.40.4-0.40.4-0.4-0.4-0.30.30.3-0.3-0.4-0.3
Total resting periods, locomotor time 20.00.00.00.10.10.10.1-0.10.1-0.1-0.00.1-0.1-0.00.0-0.1-0.0
Rest time, locomotor task time 21.31.52.01.31.3-1.1-1.21.2-1.21.21.41.3-1.3-1.41.21.01.2
Distance moved, locomotor task time 20.81.01.5-1.1-1.10.90.9-0.90.9-0.9-1.2-1.11.11.1-0.9-0.6-0.9
Vertical activity count, locomotor time 20.30.40.7-0.7-0.70.50.5-0.50.5-0.5-0.8-0.70.70.8-0.4-0.1-0.6
Weight adjusted by age0.00.00.1-0.1-0.0-0.1-0.10.1-0.10.10.2-0.10.1-0.20.2-0.20.0
Seeking ratio, delayed vs. immediate footshock0.00.00.00.00.2-0.1-0.10.1-0.10.10.00.0-0.0-0.00.0-0.10.1
Locomotion in novel chamber1.01.22.1-1.1-1.11.01.0-1.01.0-1.0-1.4-1.11.11.4-1.0-1.0-1.0
Locomotion in novel chamber post-restriction2.83.44.7-2.0-1.91.81.7-1.81.7-1.8-1.8-2.02.01.8-1.6-2.2-1.8
Progressive ratio0.10.10.3-0.00.3-0.3-0.30.3-0.40.30.3-0.00.0-0.20.50.30.3
Food seeking constrained by brief footshock4.85.87.82.22.2-2.6-2.62.6-2.62.62.12.2-2.2-2.12.42.82.4
Seeking ratio, punishment vs. effort0.50.60.80.90.7-0.8-0.70.7-0.70.70.60.9-0.9-0.60.50.90.7
Run reversals in cocaine runway, females0.10.10.3-0.4-0.40.30.3-0.30.3-0.3-0.2-0.40.40.3-0.50.1-0.4
Run reversals in cocaine runway, males0.10.10.30.20.3-0.4-0.40.4-0.40.40.40.2-0.2-0.40.20.50.3
Latency to leave start box in cocaine runway0.60.71.11.00.7-0.9-0.90.9-0.90.90.51.0-1.0-0.50.81.00.8
Latency to leave start box in cocaine runway, F0.60.60.91.00.7-0.8-0.80.8-0.80.80.71.0-1.0-0.80.70.80.8
Latency to leave start box in cocaine runway, M0.90.81.40.80.7-1.0-1.01.0-1.01.00.40.8-0.8-0.40.91.20.9
Cd content in liver0.00.00.10.10.10.10.1-0.10.1-0.10.10.1-0.1-0.10.1-0.3-0.0
Co content in liver5.66.68.12.62.6-2.5-2.52.5-2.52.52.62.6-2.6-2.62.52.82.5
Cu content in liver0.00.00.10.20.1-0.2-0.20.2-0.20.20.10.2-0.2-0.10.3-0.00.2
Fe content in liver0.00.00.0-0.1-0.1-0.0-0.00.0-0.00.0-0.1-0.10.10.1-0.0-0.2-0.0
K content in liver0.10.10.4-0.1-0.10.50.5-0.50.5-0.5-0.1-0.10.10.1-0.2-0.6-0.3
Mg content in liver0.30.30.8-0.3-0.30.60.7-0.70.7-0.7-0.3-0.30.30.3-0.3-0.9-0.5
Mn content in liver0.50.60.70.80.8-0.7-0.70.7-0.70.70.80.8-0.8-0.80.80.40.8
Na content in liver0.60.70.90.80.8-0.8-0.80.8-0.80.80.80.8-0.8-0.80.80.90.8
Rb content in liver0.00.00.3-0.1-0.10.20.2-0.20.2-0.2-0.1-0.10.10.1-0.0-0.6-0.1
Se content in liver0.30.41.0-0.6-0.60.60.6-0.70.6-0.7-0.6-0.60.60.6-0.4-1.0-0.6
Sr content in liver0.10.10.2-0.3-0.30.40.4-0.40.4-0.4-0.3-0.30.30.3-0.4-0.2-0.4
Zn content in liver1.41.61.9-1.2-1.31.31.3-1.41.3-1.3-1.3-1.21.21.3-1.0-1.4-1.3