Hub : Genes

Cluap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007117 0.05 0.03 1.8e-04 0.04 0.03 0.03 0.03 4.4e-05 1.1e-04 3.9e-04 1.2e-04
2 BLA gene expression ENSRNOG00000007117 0.1 0.06 2.2e-03 0.04 0.04 0.04 0.04 2.4e-03 5.4e-03 3.3e-03 4.3e-03
3 Brain gene expression ENSRNOG00000007117 0.13 0.07 9.1e-07 0.08 0.08 0.08 0.08 3.0e-08 6.9e-08 4.2e-08 4.5e-08
4 Eye intron excision ratio chr10:11613687:11615416 0.36 0.17 3.1e-03 0.11 0.19 0.14 0.18 1.0e-02 8.3e-04 3.2e-03 1.1e-03
5 Liver gene expression ENSRNOG00000007117 0.17 0.08 4.5e-10 0.06 0.09 0.09 0.09 6.0e-07 7.4e-10 1.2e-10 2.8e-10
6 Liver intron excision ratio chr10:11612608:11613603 0.03 0.02 4.3e-03 0.01 0.01 0 0 5.7e-02 1.5e-02 2.3e-01 1.1e-01
7 NAcc gene expression ENSRNOG00000007117 0.12 0.05 1.2e-07 0.09 0.09 0.07 0.08 2.2e-07 5.6e-07 1.2e-05 1.3e-06
8 PL gene expression ENSRNOG00000007117 0.04 0.03 8.0e-03 0.03 0.02 0.03 0.02 2.2e-03 1.2e-02 4.6e-03 5.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.10.31.10.7-0.40.11.0-0.50.80.10.1
BMI without tail0.40.83.4-0.20.80.90.0-1.9-0.70.70.8
Body weight0.93.99.4-2.71.11.2-1.4-3.1-2.41.71.2
Epididymis fat weight0.30.83.4-1.8-0.4-0.4-0.6-0.6-1.3-0.3-0.3
Glucose1.01.63.61.01.91.5-0.7-0.30.21.71.5
Heart weight0.81.11.8-0.81.20.7-1.4-0.8-1.31.20.8
Left kidney weight1.54.28.4-2.51.41.1-2.3-2.3-2.91.91.2
Right kidney weight1.02.85.9-2.31.20.8-1.9-1.6-2.41.40.8
Tail length2.16.311.3-3.02.21.5-2.4-3.3-3.42.01.5
Length with tail2.810.421.8-4.72.11.6-3.5-3.4-4.62.51.7
Length without tail0.71.56.6-2.6-0.2-0.4-1.2-0.9-1.60.6-0.4
Liver weight, left0.10.20.9-0.90.00.2-0.6-0.0-0.7-0.10.2
Liver weight, right0.10.21.00.21.00.1-0.1-0.50.40.40.0
Parametrial fat weight0.61.23.6-0.61.20.7-1.9-0.1-1.11.20.7
Retroperitoneal fat weight1.03.410.7-3.30.6-0.2-1.8-1.8-3.00.4-0.3
Intraocular pressure0.60.91.70.70.91.2-1.00.5-0.31.31.1
Extensor digitorum longus weight0.31.27.1-0.70.80.70.1-2.7-0.30.70.7
Soleus weight1.85.418.1-3.01.41.5-1.3-4.3-2.31.61.5
Tibialis anterior weight0.51.66.7-1.30.81.0-0.3-2.6-0.80.91.0
Tibia length0.10.20.50.0-0.3-0.7-0.20.70.1-0.1-0.6
Number of licking bursts0.00.00.1-0.3-0.1-0.2-0.00.0-0.3-0.3-0.2
Food consumed during 24 hour testing period5.46.510.03.1-2.2-1.72.63.23.2-2.3-1.7
Times rat made contact with spout1.01.24.81.1-0.8-0.20.42.21.3-0.8-0.2
Mean time between licks in bursts1.11.52.40.21.51.6-1.50.0-0.91.51.6
Mean num. licks in bursts0.20.31.10.4-0.5-0.10.11.10.8-0.3-0.1
Std. dev. time between licks in bursts0.30.30.60.70.80.6-0.4-0.0-0.20.80.6
Water consumed over 24 hours3.03.54.91.2-2.1-1.91.92.01.7-2.2-1.9
Indifference point 0 sec0.00.00.1-0.20.2-0.30.00.00.1-0.2-0.3
Indifference point AUC0.20.20.5-0.40.70.6-0.60.1-0.50.40.5
Indifference point function ln k0.40.51.00.4-0.7-0.81.00.10.8-0.9-0.7
Indifference point function log k0.40.51.00.4-0.7-0.81.00.10.8-0.9-0.7
Delay discounting total patch changes 0 sec0.00.00.2-0.30.5-0.1-0.2-0.2-0.20.0-0.1
Delay discounting total patch changes 12 sec0.00.10.1-0.4-0.2-0.30.20.0-0.0-0.3-0.3
Delay discounting total patch changes 18 sec0.10.20.4-0.00.60.5-0.50.3-0.10.50.5
Delay discounting total patch changes 24 sec0.50.61.8-1.4-0.4-0.8-0.0-1.0-0.8-0.3-0.8
Delay discounting total patch changes 6 sec0.20.30.60.2-0.2-0.70.80.30.6-0.7-0.7
Delay discounting time to switch 0 sec1.42.14.4-0.41.51.9-1.6-0.8-0.82.11.7
Delay discounting water rate 0 sec2.33.64.91.5-1.7-2.21.81.91.8-2.1-2.1
Delay discounting water rate 12 sec1.62.43.41.3-1.8-1.81.51.11.2-1.7-1.7
Delay discounting water rate 18 sec0.50.71.90.3-1.4-0.90.8-0.00.3-1.0-0.9
Delay discounting water rate 24 sec1.21.63.30.9-1.6-1.40.71.30.4-1.8-1.5
Delay discounting water rate 6 sec0.60.81.70.6-0.7-1.31.10.20.8-0.8-1.2
Locomotor activity0.91.43.4-1.50.10.7-1.2-1.6-1.80.70.8
Locomotor testing distance0.81.32.8-0.90.41.2-1.2-1.1-1.70.81.3
Locomotor testing rearing1.82.95.30.11.52.1-2.30.1-1.52.02.2
Light reinforcement 10.40.71.10.10.60.9-1.0-0.3-0.90.91.0
Light reinforcement 20.60.82.91.0-0.1-0.90.01.70.6-0.4-0.9
Reaction time number correct0.91.33.5-0.50.90.5-1.7-0.5-1.91.20.7
Reaction time mean minus median2.33.05.60.1-2.4-1.91.81.20.9-2.3-2.0
Reaction time mean minus median AUC1.72.24.7-0.4-2.2-1.61.50.90.4-2.1-1.7
Reaction time num false alarms9.412.926.6-5.02.52.5-3.7-3.7-5.22.22.5
Reaction time num false alarms AUC8.512.024.7-5.02.42.4-3.4-3.7-4.92.12.4
Reaction time trials correct on left0.91.33.5-0.50.90.5-1.7-0.5-1.91.20.7
Reaction time trials on left0.81.23.5-0.50.90.4-1.6-0.5-1.91.10.7
Reaction time mean0.20.30.70.7-0.60.30.50.80.5-0.20.4
Reaction time mean AUC0.40.51.10.7-1.0-0.10.81.00.6-0.6-0.1
Median of all reaction times0.40.51.40.90.11.10.00.50.30.71.2
Reaction time omissions0.60.81.50.0-0.9-1.20.90.80.2-1.1-1.2
Reaction time false alarm rate4.15.915.5-3.91.51.8-1.9-2.9-3.11.11.7
Reaction time premature initiation rate0.60.91.9-1.40.40.6-1.0-1.0-1.10.50.9
Reaction time premature initiations1.42.04.1-1.70.80.8-1.8-1.3-2.01.11.1
Std. dev. reaction times0.50.71.8-0.7-1.3-0.80.50.6-0.3-1.2-0.8
Reaction time trials completed0.81.23.5-0.50.90.4-1.6-0.5-1.91.10.7
Reaction time trials AUC1.11.63.8-0.41.10.7-1.9-0.5-2.01.41.0
Social response proportion0.90.92.51.4-0.1-0.70.71.61.4-0.2-0.6
Social responses0.20.20.7-0.2-0.4-0.80.50.10.1-0.6-0.7
Social time0.30.41.6-1.0-0.50.0-0.2-1.3-0.60.2-0.0
Conditioned locomotion1.31.62.7-1.21.11.2-1.7-1.0-1.51.11.2
Cocaine response after cond. corrected0.91.01.8-0.21.01.3-1.30.1-0.91.01.3
Cocaine response after cond. not corrected1.31.42.4-0.31.31.6-1.4-0.3-1.11.21.6
Cocaine response before conditioning0.40.50.90.9-0.5-0.60.90.30.8-0.7-0.6
Saline control response1.11.52.60.6-1.5-1.41.6-0.01.0-1.5-1.4
Condit. Reinf. active minus inactive responses1.92.35.92.3-1.1-0.61.22.41.5-1.4-0.6
Condit. Reinf. active-inactive response ratio1.61.63.21.8-1.0-0.71.11.81.3-1.3-0.7
Condit. Reinf. active responses2.43.37.02.6-1.3-0.51.82.62.2-1.5-0.5
Condit. Reinf. inactive responses0.80.92.41.5-0.30.21.01.31.4-0.30.2
Condit. Reinf. lever presses2.73.78.72.9-1.3-0.71.63.02.2-1.5-0.7
Condit. Reinf. lever reinforcers received2.53.58.52.9-1.2-0.31.72.92.3-1.4-0.3
Pavlov. Cond. lever latency1.72.37.4-2.70.6-0.0-1.2-2.2-1.90.7-0.0
Pavlov. Cond. magazine entry latency1.61.98.02.3-0.4-0.10.22.81.1-0.4-0.1
Pavlov. Cond. change in total contacts2.33.211.53.4-0.30.20.93.02.0-0.50.2
Pavlov. Cond. index score2.12.79.23.0-0.50.10.82.81.9-0.50.1
Pavlov. Cond. latency score2.02.58.72.9-0.40.10.72.71.8-0.40.1
Pavlov. Cond. lever contacts0.91.34.72.2-0.50.30.91.61.3-0.60.3
Pavlov. Cond. magazine entry number3.74.511.5-3.11.51.1-1.6-3.4-2.41.51.1
Pavlov. Cond. intertrial magazine entries0.40.51.30.4-0.8-0.61.10.20.8-0.9-0.6
Pavlov. Cond. lever-magazine prob. diff.2.02.68.52.9-0.6-0.00.92.71.8-0.6-0.0
Pavlov. Cond. response bias1.62.27.42.7-0.60.11.12.31.7-0.80.1
Conditioned reinforcement - actives1.71.72.8-1.40.91.3-1.0-1.7-1.31.21.4
Conditioned reinforcement - inactives0.10.20.3-0.4-0.60.60.2-0.10.20.30.6
Conditioned locomotion0.50.61.7-1.00.50.7-0.2-1.3-0.70.40.7
Intermittent access intake day 1-15 change1.41.43.6-1.4-0.01.4-0.5-1.9-1.30.71.3
Intermittent access intake escalation1.01.02.3-1.2-0.11.0-0.5-1.5-1.10.61.1
Intermittent access intake escalation 21.41.41.9-1.10.51.3-1.1-1.2-1.41.01.4
Intermitt. access day 1 inactive lever presses0.20.30.8-0.9-0.6-0.3-0.3-0.1-0.7-0.1-0.4
Intermitt. access day 15 inactive lever presses1.51.72.5-1.30.81.5-1.4-0.7-1.61.41.5
Intermitt. access escalation Index2.92.65.2-2.01.11.1-1.9-1.7-2.31.21.0
Intermittent access day 1 total infusions0.00.00.0-0.1-0.2-0.0-0.0-0.2-0.0-0.2-0.1
Intermittent access day 15 total infusions0.50.51.4-0.6-0.10.9-0.3-1.2-0.70.40.9
Intermittent access terminal intake (last 3 days)1.01.12.1-1.20.01.1-0.8-1.5-1.30.51.0
Intermittent access total infusions0.20.20.5-0.3-0.20.6-0.2-0.7-0.50.10.5
Intermittent access day 1 locomotion0.00.00.10.0-0.1-0.2-0.1-0.2-0.2-0.2-0.2
Intermittent access day 15 total locomotion0.30.30.6-0.8-0.3-0.30.6-0.8-0.1-0.6-0.2
Intermittent access total locomotion0.60.61.0-1.0-0.8-0.60.7-1.0-0.4-0.9-0.7
Intermittent access standard deviation0.91.02.8-1.0-0.21.0-0.6-1.7-1.20.61.0
Cocaine induced anxiety0.20.20.60.80.20.2-0.20.60.4-0.00.2
Post-drug Anxiety0.30.31.50.0-0.1-0.7-0.31.20.0-0.5-0.7
Baseline Anxiety0.10.10.5-0.7-0.2-0.4-0.20.1-0.4-0.1-0.4
Lifetime Intake0.10.10.2-0.1-0.50.3-0.1-0.3-0.3-0.10.3
Incentive Sensitization - Responses2.12.15.0-2.20.21.2-1.2-1.7-2.00.71.2
Incentive Sensitization - Breakpoint2.12.25.1-2.30.31.1-1.2-1.8-2.00.81.2
Progressive ratio test 1 active lever presses1.21.23.20.7-1.8-1.11.20.50.9-1.2-1.1
Progressive ratio test 1 breakpoint1.61.74.20.6-2.0-1.31.50.40.9-1.5-1.3
Progressive ratio test 1 inactive lever presses0.40.52.4-0.5-1.5-0.60.10.5-0.3-0.5-0.5
Progressive ratio test 2 active lever presses0.50.51.5-1.2-0.70.2-0.1-1.0-1.0-0.20.2
Progressive ratio test 2 breakpoint0.50.61.6-1.3-0.60.4-0.3-1.1-1.1-0.10.3
Progressive ratio test 2 inactive lever presses0.10.10.40.3-0.6-0.00.30.60.3-0.20.0
Total sessions with >9 infusions0.91.01.60.9-1.2-1.00.71.30.9-1.0-1.0
Short access day 1 total inactive lever presses0.20.30.8-0.1-0.00.5-0.90.6-0.40.50.5
Short access day 10 total inactive lever presses0.50.52.0-1.40.4-0.1-0.7-0.2-1.20.1-0.1
Short access day 1 total infusions0.10.10.7-0.3-0.8-0.2-0.10.1-0.3-0.3-0.3
Short access day 10 total infusions0.10.10.80.90.10.10.00.50.3-0.1-0.1
Short access total infusions0.10.10.3-0.0-0.60.2-0.1-0.1-0.2-0.10.1
Short access day 1 locomotion0.30.30.60.8-0.8-0.30.70.60.7-0.1-0.4
Short access day 10 total locomotion0.10.10.30.1-0.0-0.60.5-0.20.3-0.3-0.5
Short access total locomotion1.21.21.90.4-1.4-1.31.20.50.7-1.2-1.4
Compulsive drug intake0.20.20.60.80.2-0.40.00.60.60.1-0.1
One hour access (0.3 mA shock)0.60.71.7-0.3-1.3-0.71.1-0.60.3-1.1-0.6
One hour access (shock baseline)0.50.61.5-0.3-1.2-0.70.8-0.4-0.0-1.1-0.7
Number of responses in last shaping day0.10.10.20.3-0.40.3-0.20.2-0.30.20.2
Context. condit. distance diff. score0.70.81.50.31.01.2-1.0-0.3-0.51.11.2
Locomotion velocity, session 10.30.40.80.60.50.9-0.20.60.10.60.9
Locomotion distance, session 10.20.31.00.0-1.00.00.70.40.4-0.9-0.0
Locomotion velocity, session 20.40.40.80.9-0.2-0.40.70.90.9-0.3-0.4
Locomotion distance, session 20.30.40.70.3-0.8-0.40.80.70.7-0.8-0.4
Locomotion velocity, session 30.50.61.0-0.60.80.8-0.5-1.0-0.40.90.8
Locomotion distance, session 30.10.10.2-0.1-0.3-0.40.20.00.5-0.0-0.4
Stereotopy head waving bouts, day 30.70.81.3-0.80.90.7-1.1-1.0-1.01.00.7
Stereotopy head waving duration, day 30.30.30.6-0.70.4-0.2-0.7-0.8-0.80.4-0.2
Locomotion velocity, session 72.02.24.3-0.21.71.7-2.1-0.3-1.11.91.7
Locomotion distance, session 70.60.81.80.50.61.4-1.10.5-0.30.81.4
Stereotopy head waving bouts, day 70.60.71.80.51.30.8-0.90.1-0.21.20.8
Stereotopy head waving duration, day 70.50.61.7-0.11.30.6-0.9-0.5-0.51.10.6
Locomotion velocity, session 80.40.41.11.0-0.00.30.50.91.10.10.3
Locomotion distance, session 80.10.20.40.50.10.6-0.20.40.20.20.6
Degree of sensitization distance0.50.51.3-0.00.31.1-0.90.1-0.80.41.2
Degree of sensitization stereotypy1.11.22.40.51.51.4-1.10.1-0.41.41.4
Condit. Reinf. active minus inactive responses0.70.71.8-0.30.31.0-1.30.5-1.30.51.0
Condit. Reinf. active-inactive response ratio0.30.31.70.7-0.5-0.1-0.21.3-0.1-0.2-0.0
Condit. Reinf. active responses1.41.73.4-0.80.91.5-1.80.0-1.81.01.5
Condit. Reinf. inactive responses1.31.62.7-1.31.01.3-1.5-0.9-1.61.01.3
Incentive salience index mean0.40.51.8-0.8-0.00.4-1.10.4-1.40.20.4
Condit. Reinf. lever presses0.30.41.6-0.2-0.7-0.60.11.30.2-0.6-0.6
Time in familiar zone, hab. session 10.10.10.40.60.10.40.3-0.20.30.30.3
Time in novel zone, hab. session 10.80.81.6-0.70.90.7-1.3-0.4-1.20.90.7
Total zone transitions, hab. session 10.50.71.00.2-1.0-0.90.90.80.7-1.0-0.9
Total locomotion distance, hab. session 10.30.41.0-0.5-0.7-1.00.60.30.2-0.6-1.0
Locomotion velocity, hab. session 10.40.61.1-0.5-0.8-1.10.80.30.4-0.8-1.1
Time in familiar zone, hab. session 20.40.41.4-0.31.00.5-0.3-1.2-0.30.60.4
Time in novel zone, hab. session 20.20.20.4-0.1-0.5-0.50.30.6-0.3-0.6-0.5
Total zone transitions, hab. session 20.40.51.3-1.1-0.7-0.70.10.1-0.5-0.8-0.7
Total locomotion distance, hab. session 20.71.04.3-2.10.20.1-0.5-1.3-1.30.10.1
Locomotion velocity, hab. session 20.40.52.7-1.6-0.1-0.2-0.1-0.8-0.6-0.2-0.2
Novel to familiar place preference ratio0.00.10.20.20.3-0.00.10.50.20.10.0
Novelty place preference0.00.00.20.20.4-0.00.10.30.10.30.0
Time in novel zone, NPP test0.10.10.20.40.50.10.10.30.10.40.1
Total zone transitions, NPP test0.40.61.00.5-0.9-0.61.00.81.0-0.8-0.6
Total locomotion distance, NPP test0.60.81.30.2-0.8-1.11.10.41.1-0.9-1.1
Locomotion velocity, NPP test0.81.11.80.3-1.0-1.21.30.61.3-1.1-1.2
Pavlov. Cond. lever latency0.50.71.30.01.10.9-0.6-1.1-0.40.90.9
Pavlov. Cond. magazine entry latency0.60.72.40.4-1.1-0.70.11.60.5-0.9-0.7
Pavlov. Cond. change in total contacts0.80.81.8-0.2-1.3-1.10.41.00.1-1.1-1.1
Pavlov. Cond. index score0.70.81.90.1-1.2-1.00.41.40.5-0.9-1.1
Pavlov. Cond. latency score0.91.22.60.3-1.4-1.20.61.60.8-1.1-1.2
Pavlov. Cond. lever contacts0.70.91.8-0.1-1.3-1.10.51.10.3-1.0-1.2
Pavlov. Cond. magazine entry number0.40.51.6-0.40.80.6-0.1-1.3-0.50.60.6
Pavlov. Cond. intertrial magazine entries0.50.61.4-0.8-1.1-0.80.10.1-0.7-1.2-0.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.60.0-1.2-1.00.41.30.5-1.0-1.0
Pavlov. Cond. response bias0.40.51.50.3-0.9-0.70.21.20.4-0.7-0.8
Bone: apparent density1.42.33.7-0.81.71.3-1.7-1.5-1.61.91.3
Bone surface0.10.20.7-0.50.1-0.1-0.5-0.6-0.80.4-0.0
Bone volume0.71.22.2-0.51.10.9-1.3-1.1-1.31.50.9
Bone: connectivity density1.42.23.2-0.91.51.3-1.7-1.6-1.61.81.3
Bone: cortical apparent density0.70.92.10.0-1.5-1.00.70.80.5-1.3-0.9
Bone: cortical area0.10.20.90.9-0.3-0.40.2-0.00.20.1-0.4
Bone: cortical porosity1.92.16.4-2.50.00.3-1.3-1.5-2.50.10.3
Bone: cortical porosity1.41.55.2-2.1-0.2-0.1-1.1-0.9-2.3-0.2-0.1
Bone: cortical thickness0.50.83.11.7-0.7-0.70.71.00.9-0.3-0.7
Bone: cortical thickness2.12.43.60.21.71.9-1.9-0.6-1.41.91.9
Bone: cortical tissue density0.60.82.0-0.2-1.4-0.90.60.70.4-1.3-0.9
Bone: elastic displacement0.50.61.80.7-0.8-0.51.30.10.8-0.8-0.5
Bone: elastic work0.30.40.70.5-0.8-0.70.80.10.1-0.8-0.7
Bone: endosteal estimation1.12.45.7-2.41.20.8-1.5-1.9-2.11.00.8
Bone: endosteal perimeter0.81.74.6-0.71.41.1-0.9-2.2-1.21.41.1
Bone: final force0.50.92.8-1.10.30.3-1.1-0.9-1.70.70.4
Bone: final moment0.30.62.1-1.0-0.00.2-0.8-0.8-1.40.40.2
Bone: marrow area1.12.45.8-2.41.10.7-1.5-1.9-2.10.90.7
Bone: maximum diameter0.20.31.31.10.30.10.4-0.70.50.50.1
Bone: maximum force0.10.20.6-0.5-0.2-0.4-0.3-0.4-0.80.1-0.4
Bone: maximum moment0.10.10.3-0.4-0.5-0.50.0-0.2-0.5-0.2-0.5
Bone: minimum diameter0.10.20.8-0.40.30.2-0.5-0.6-0.90.40.2
Bone: periosteal estimation0.40.81.6-1.00.60.4-0.9-1.3-1.30.80.4
Bone: periosteal perimeter0.61.12.20.21.21.0-0.7-1.5-0.71.41.0
Bone: post-yield work0.20.20.5-0.7-0.4-0.5-0.30.3-0.7-0.3-0.5
Bone: stiffness0.50.91.4-0.61.10.7-1.0-1.0-0.91.20.7
Bone: tissue strength2.82.75.41.7-1.8-1.41.42.31.3-1.7-1.4
Bone: trabecular number0.10.20.5-0.20.2-0.1-0.5-0.5-0.70.6-0.1
Bone: trabecular spacing0.50.71.91.20.50.60.21.41.00.00.6
Bone: trabecular thickness0.10.10.40.10.40.1-0.7-0.2-0.40.50.1
Bone: trabecular tissue density0.10.10.2-0.4-0.2-0.30.5-0.30.1-0.4-0.3
Breakpoint value in progressive ratio session0.50.60.80.4-0.9-0.80.90.60.8-0.6-0.9
Distance traveled before self-admin4.14.414.4-1.91.61.5-1.2-3.8-1.92.11.7
Distance traveled after self-admin4.04.47.5-1.81.82.1-1.9-2.7-2.32.02.0
Delta time in closed arm before/after self-admin0.60.51.0-0.8-0.8-0.9-0.20.5-0.4-0.9-1.0
Delta time in open arm before/after self-admin0.10.10.50.6-0.20.3-0.10.70.20.20.2
Diff in mean of infusions in LGA sessions1.11.22.90.1-1.7-1.11.40.41.0-1.0-1.1
Extinction: sum of active levers before priming3.43.55.01.4-2.2-2.01.62.01.6-2.0-1.9
Active lever presses in extinction session 60.40.41.10.5-0.8-0.61.1-0.10.8-0.3-0.5
Delta distance traveled before/after self-admin0.40.42.30.2-0.50.2-0.51.5-0.2-0.60.0
Delta ambulatory time before/after self-admin0.50.53.20.4-0.00.2-0.51.8-0.0-0.50.1
Time in closed arm before self-admin2.22.55.1-1.51.61.3-1.4-2.3-1.71.41.4
Time in closed arm after self-admin0.91.03.1-1.8-0.4-0.8-0.7-0.6-1.4-0.6-0.7
Time in open arm before self-admin1.21.22.01.0-1.4-1.01.40.81.3-0.8-0.9
Time in open arm after self-admin0.20.20.40.6-0.50.10.60.40.6-0.00.1
Sum of active levers in priming session hrs 5-61.71.73.81.5-1.4-1.20.71.91.3-0.8-1.1
Time to tail flick, vehicle, before self-admin0.10.10.50.10.20.3-0.70.1-0.60.10.2
Time to tail flick, vehicle, after self-admin3.33.56.9-2.31.41.5-2.3-1.3-2.61.61.6
Time to tail flick, test, before self-admin4.14.16.5-0.52.22.6-2.0-1.6-1.72.32.5
Time to tail flick, test, after self-admin0.00.00.30.60.1-0.20.00.0-0.00.0-0.1
Delta time to tail flick, vehicle, before/after SA1.71.64.5-2.10.70.7-1.1-1.5-1.80.70.8
Delta time to tail flick, test, before/after SA1.51.41.90.8-1.1-1.41.30.91.3-1.1-1.3
Ambulatory time before self-admin3.43.613.4-1.71.41.4-0.8-3.7-1.61.71.6
Ambulatory time after self-admin2.83.14.2-1.21.62.0-1.7-2.0-1.81.71.9
Total heroin consumption0.10.10.20.50.40.20.2-0.40.30.20.2
Area under the delay curve0.10.10.50.00.7-0.0-0.20.0-0.2-0.00.1
Delay disc. indifference point, 0s delay0.10.10.9-0.01.0-0.3-0.2-0.1-0.20.1-0.2
Delay disc. indifference point, 16s delay0.30.31.2-0.01.10.5-0.7-0.1-0.20.30.5
Delay disc. indifference point, 2s delay0.80.92.4-1.21.00.3-1.0-0.9-1.50.40.5
Delay disc. indifference point, 24s delay0.30.31.60.50.1-0.20.01.30.7-0.1-0.1
Delay disc. indifference point, 4s delay1.71.83.5-0.11.91.6-1.3-1.1-1.01.41.7
Delay disc. indifference point, 8s delay0.00.00.1-0.1-0.0-0.20.3-0.1-0.1-0.2-0.0
Delay discount exponential model param0.10.10.4-0.0-0.6-0.00.3-0.00.3-0.0-0.1
Delay discount hyperbolic model param0.30.31.00.2-1.0-0.30.60.40.7-0.4-0.5
Fecal boli incidents, locomotor time 10.80.81.5-0.31.01.1-1.2-0.2-0.71.11.1
Change in fecal boli incidents, locomotor task0.20.21.0-1.0-0.30.30.0-0.6-0.20.20.3
Time >=10cm from walls, locomotor time 11.21.24.9-1.21.00.6-0.5-2.2-1.10.60.6
Bouts of movement, locomotor time 11.31.45.22.3-0.20.21.20.72.00.40.2
Total resting periods, locomotor time 10.91.03.92.0-0.30.41.00.51.60.40.3
Rest time, locomotor task time 10.90.91.60.9-1.0-0.81.10.91.3-0.9-0.7
Distance moved, locomotor task time 11.41.53.8-1.90.70.4-1.1-1.5-1.90.40.4
Vertical activity count, locomotor time 12.42.54.0-1.62.01.4-1.4-1.8-1.81.31.3
Time >=10cm from walls, locomotor time 21.71.84.4-1.60.80.8-1.2-2.1-1.90.80.6
Bouts of movement, locomotor time 20.20.20.40.10.70.50.5-0.60.20.60.5
Total resting periods, locomotor time 20.30.30.50.30.70.60.3-0.60.30.70.6
Rest time, locomotor task time 21.31.54.61.5-0.5-0.81.51.12.2-0.6-0.5
Distance moved, locomotor task time 21.41.63.9-1.40.80.8-1.7-1.3-2.00.70.7
Vertical activity count, locomotor time 24.34.76.4-2.02.32.1-2.5-2.1-2.51.91.8
Weight adjusted by age0.91.03.31.8-0.00.40.11.51.40.50.5
Seeking ratio, delayed vs. immediate footshock2.73.15.72.1-2.2-0.51.72.42.3-1.2-0.5
Locomotion in novel chamber0.50.61.10.5-1.1-0.70.90.50.8-0.8-0.8
Locomotion in novel chamber post-restriction0.30.30.8-0.8-0.90.3-0.70.1-0.8-0.0-0.1
Progressive ratio0.60.72.30.1-1.5-0.41.30.01.0-0.7-0.4
Food seeking constrained by brief footshock1.31.63.51.9-1.1-0.51.50.61.6-1.2-0.9
Seeking ratio, punishment vs. effort0.10.20.70.80.80.0-0.20.00.00.0-0.1
Run reversals in cocaine runway, females1.11.11.7-0.81.31.2-1.3-0.0-1.20.80.9
Run reversals in cocaine runway, males1.01.02.1-0.30.51.4-0.9-0.9-0.81.01.5
Latency to leave start box in cocaine runway0.10.10.4-0.2-0.30.40.30.40.2-0.6-0.1
Latency to leave start box in cocaine runway, F0.10.10.60.1-0.20.1-0.20.80.0-0.5-0.2
Latency to leave start box in cocaine runway, M0.30.31.0-0.0-0.3-0.11.00.10.7-0.6-0.5
Cd content in liver1.01.13.11.8-0.8-0.11.40.91.4-0.7-0.1
Co content in liver0.60.71.40.5-0.7-1.20.90.40.8-0.8-1.2
Cu content in liver0.81.02.3-1.21.00.8-0.7-1.5-0.91.00.8
Fe content in liver0.70.81.50.6-1.0-0.71.01.21.1-0.9-0.7
K content in liver3.23.29.6-3.11.10.6-0.9-3.1-1.80.90.6
Mg content in liver0.80.82.7-1.10.80.4-0.5-1.6-0.80.70.4
Mn content in liver1.21.43.0-0.6-1.5-1.70.70.1-0.2-1.4-1.7
Na content in liver0.91.02.3-1.0-0.9-1.50.40.4-0.0-1.1-1.5
Rb content in liver2.53.26.01.6-1.6-1.42.31.42.4-1.9-1.4
Se content in liver1.41.73.3-0.1-1.5-1.80.81.20.1-1.6-1.8
Sr content in liver0.80.81.9-0.51.00.6-0.7-1.4-0.91.00.6
Zn content in liver2.62.95.7-1.91.71.3-1.5-2.4-1.71.61.3