Hub : Genes

Amigo2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000007032 0.08 0.06 2.5e-10 0.09 0.08 0.08 0.08 1.2e-09 2.7e-09 4.1e-09 2.0e-09
2 BLA gene expression ENSRNOG00000007032 0.1 0.09 3.4e-04 0.04 0.04 0.06 0.04 2.0e-03 3.3e-03 6.8e-04 1.8e-03
3 Brain gene expression ENSRNOG00000007032 0.09 0.08 4.6e-06 0.04 0.04 0.05 0.04 6.4e-05 6.6e-05 3.6e-05 1.0e-04
4 Brain mRNA stability ENSRNOG00000007032 0.07 0.05 8.5e-06 0.06 0.05 0.04 0.05 6.9e-06 9.4e-06 9.7e-05 1.7e-05
5 Eye gene expression ENSRNOG00000007032 0.19 0.15 9.8e-03 0.12 0.12 0.07 0.1 6.1e-03 6.0e-03 2.7e-02 1.1e-02
6 Eye mRNA stability ENSRNOG00000007032 0.21 0.14 4.2e-03 0.11 0.16 0.1 0.11 9.3e-03 1.9e-03 1.2e-02 9.4e-03
7 LHb intron excision ratio chr7:128393946:128394297 0.48 0.26 8.6e-03 0.03 0.03 0.04 0.04 5.5e-02 6.7e-02 3.6e-02 5.1e-02
8 Liver gene expression ENSRNOG00000007032 0.04 0.03 1.8e-05 0.03 0.04 0.03 0.03 6.8e-04 8.5e-05 4.1e-04 6.5e-04
9 Liver intron excision ratio chr7:128393946:128394297 0.14 0.11 1.3e-04 0.03 0.02 0.02 0.03 1.4e-04 8.7e-04 3.9e-03 1.2e-04
10 NAcc mRNA stability ENSRNOG00000007032 0.07 0.07 1.1e-03 0.04 0.03 0.02 0.03 5.6e-04 4.1e-03 6.9e-03 2.1e-03
11 PL mRNA stability ENSRNOG00000007032 0.14 0.08 3.3e-03 0.02 0.02 0.02 0.02 8.9e-03 6.4e-03 9.2e-03 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail2.89.014.52.63.83.43.73.83.41.93.32.42.0-1.3
BMI without tail0.40.95.2-0.70.6-0.20.10.1-0.2-1.3-0.3-0.3-1.4-2.3
Body weight4.217.927.33.85.24.75.15.24.93.14.83.53.4-0.5
Epididymis fat weight0.61.43.20.91.81.51.61.31.00.51.01.30.6-0.8
Glucose0.20.31.9-0.00.1-0.10.10.30.1-0.60.0-0.7-0.8-1.4
Heart weight0.30.53.1-0.30.2-0.4-0.3-0.0-0.2-1.1-0.3-0.4-0.6-1.8
Left kidney weight0.51.44.31.32.11.40.81.10.90.40.91.70.6-0.6
Right kidney weight1.44.17.32.32.42.22.02.72.51.12.41.41.4-0.9
Tail length0.31.02.5-0.9-0.2-1.0-0.6-0.5-0.7-1.3-0.7-1.2-1.5-1.6
Length with tail1.34.76.81.92.62.22.42.62.61.92.51.62.10.2
Length without tail6.814.918.53.83.84.24.04.14.23.84.23.44.31.8
Liver weight, left2.33.75.92.41.52.31.91.91.91.82.01.92.01.3
Liver weight, right1.72.93.91.71.51.81.41.61.81.61.82.01.91.5
Parametrial fat weight0.30.51.4-0.8-0.1-0.4-0.4-1.2-1.2-0.5-1.10.5-0.40.1
Retroperitoneal fat weight0.10.20.90.10.90.3-0.2-0.1-0.3-0.1-0.30.4-0.0-0.8
Intraocular pressure6.08.513.9-2.6-3.4-3.0-2.9-3.7-3.6-2.8-3.5-2.1-2.60.1
Extensor digitorum longus weight4.819.125.24.54.94.64.95.04.94.24.83.34.30.9
Soleus weight0.82.43.51.81.61.81.91.91.71.21.70.81.5-0.1
Tibialis anterior weight1.96.69.12.62.82.72.93.02.92.52.91.92.50.5
Tibia length5.916.821.94.13.34.24.24.04.34.34.43.74.73.8
Number of licking bursts0.60.72.3-0.8-1.3-1.0-0.8-0.5-0.4-0.3-0.5-1.5-0.70.2
Food consumed during 24 hour testing period1.21.42.71.11.61.41.41.31.21.01.11.21.1-0.1
Times rat made contact with spout0.10.10.30.40.50.30.60.40.30.40.30.10.1-0.2
Mean time between licks in bursts1.01.32.5-0.9-0.9-1.1-0.5-0.8-1.0-1.4-1.0-1.6-1.6-1.4
Mean num. licks in bursts0.50.62.20.71.30.90.80.30.20.30.21.50.5-0.2
Std. dev. time between licks in bursts0.50.61.0-0.4-1.0-0.7-0.7-0.9-1.0-0.6-0.9-0.8-0.7-0.1
Water consumed over 24 hours0.20.30.80.60.50.40.40.60.40.40.4-0.30.3-0.9
Indifference point 0 sec0.81.33.4-1.1-1.1-1.1-1.4-1.6-1.2-0.1-1.1-0.3-0.31.8
Indifference point AUC0.10.10.6-0.20.10.0-0.3-0.3-0.10.3-0.10.7-0.30.8
Indifference point function ln k1.52.13.91.11.61.42.01.91.81.01.80.71.1-0.2
Indifference point function log k1.52.13.91.11.61.42.01.91.81.01.80.71.1-0.2
Delay discounting total patch changes 0 sec0.71.23.3-1.0-1.1-1.0-1.2-1.5-1.1-0.0-1.1-0.3-0.21.8
Delay discounting total patch changes 12 sec0.70.95.1-0.4-1.0-0.3-1.0-1.1-0.70.5-0.60.30.52.3
Delay discounting total patch changes 18 sec1.72.24.7-1.1-2.2-1.6-1.9-1.9-1.5-0.3-1.4-0.8-0.91.6
Delay discounting total patch changes 24 sec0.81.03.4-0.7-1.9-1.1-1.1-1.0-0.9-0.2-0.8-1.4-0.50.6
Delay discounting total patch changes 6 sec1.21.83.7-1.3-1.4-1.4-1.9-1.8-1.5-0.7-1.5-0.6-0.91.3
Delay discounting time to switch 0 sec2.43.64.6-1.7-2.1-2.0-2.0-2.1-2.1-1.9-2.1-2.0-1.4-1.1
Delay discounting water rate 0 sec4.57.19.02.72.72.83.02.72.82.92.82.42.51.7
Delay discounting water rate 12 sec2.53.86.41.71.82.12.52.32.31.92.21.12.00.6
Delay discounting water rate 18 sec0.50.71.30.70.81.01.21.10.90.60.90.10.8-0.3
Delay discounting water rate 24 sec4.56.28.22.72.02.62.92.22.42.52.52.52.52.5
Delay discounting water rate 6 sec4.36.27.72.62.12.62.82.62.72.62.72.02.71.8
Locomotor activity0.71.21.7-0.8-1.2-1.3-1.2-1.2-1.2-1.1-1.1-0.9-1.2-0.4
Locomotor testing distance2.03.35.1-1.6-2.3-2.1-2.1-2.2-2.0-1.7-1.9-1.1-1.70.4
Locomotor testing rearing1.82.84.7-1.5-2.1-2.1-2.2-2.1-1.8-1.2-1.7-0.8-1.21.0
Light reinforcement 12.03.64.8-2.0-2.2-2.1-2.1-2.1-2.1-1.5-2.1-2.0-1.6-0.5
Light reinforcement 22.33.17.0-1.5-1.4-1.8-1.2-1.0-1.4-1.8-1.4-2.3-2.1-2.6
Reaction time number correct0.60.82.10.70.40.81.40.90.90.90.90.11.10.9
Reaction time mean minus median7.59.813.1-2.7-2.7-3.1-3.5-3.3-3.6-3.5-3.6-2.4-2.8-3.0
Reaction time mean minus median AUC5.16.59.0-2.0-2.2-2.6-2.9-2.7-3.0-2.7-3.0-2.1-2.2-2.5
Reaction time num false alarms1.62.14.0-2.0-1.0-1.4-1.6-1.8-1.7-1.7-1.6-0.6-1.40.2
Reaction time num false alarms AUC2.33.25.3-2.2-1.1-1.7-2.1-2.3-2.1-2.0-2.1-0.7-1.60.1
Reaction time trials correct on left0.60.82.10.70.40.81.40.90.90.90.90.11.10.9
Reaction time trials on left0.40.61.60.60.30.71.30.70.80.80.80.00.90.8
Reaction time mean0.50.62.0-0.0-0.5-0.6-1.0-0.7-1.0-0.8-1.0-0.3-0.5-1.4
Reaction time mean AUC0.20.30.90.2-0.1-0.3-0.7-0.5-0.7-0.3-0.70.00.0-0.9
Median of all reaction times0.10.10.60.80.30.3-0.00.20.10.20.00.40.4-0.7
Reaction time omissions5.37.213.5-2.2-2.4-2.6-3.7-3.4-3.4-2.5-3.3-1.5-2.1-1.1
Reaction time false alarm rate1.82.64.5-2.0-0.9-1.6-2.1-2.0-1.9-1.8-1.9-0.4-1.6-0.2
Reaction time premature initiation rate1.62.23.9-1.3-1.6-1.3-1.9-2.0-1.9-1.1-1.8-1.1-1.20.4
Reaction time premature initiations0.81.22.2-0.9-1.3-0.9-1.2-1.5-1.4-0.7-1.3-1.1-0.60.6
Std. dev. reaction times5.27.19.8-2.0-2.3-2.6-3.1-2.8-3.1-2.9-3.1-1.9-2.4-2.8
Reaction time trials completed0.40.61.60.60.30.71.30.70.80.80.80.00.90.8
Reaction time trials AUC0.81.12.60.80.71.01.61.11.11.11.10.31.21.0
Social response proportion0.70.82.0-1.0-0.7-1.0-1.4-1.0-0.9-0.8-0.9-0.6-0.5-0.3
Social responses6.78.714.3-3.0-2.8-3.3-3.8-3.5-3.4-2.8-3.3-2.3-2.3-0.9
Social time1.72.36.2-1.1-1.0-1.6-1.6-1.1-1.4-1.4-1.4-1.4-1.5-2.5
Conditioned locomotion0.30.41.8-0.5-0.3-0.7-0.2-0.2-0.3-0.6-0.4-0.8-0.7-1.3
Cocaine response after cond. corrected0.70.76.20.00.90.1-0.00.3-0.1-0.7-0.2-0.5-0.6-2.5
Cocaine response after cond. not corrected1.61.76.0-1.0-0.4-1.0-1.1-0.8-1.2-1.5-1.2-1.5-1.3-2.4
Cocaine response before conditioning4.35.39.5-2.4-3.1-2.5-2.5-2.8-2.5-1.7-2.5-1.8-1.70.8
Saline control response0.00.00.1-0.10.0-0.10.1-0.3-0.4-0.0-0.4-0.30.1-0.3
Condit. Reinf. active minus inactive responses0.10.10.2-0.5-0.1-0.3-0.3-0.1-0.10.0-0.1-0.20.4-0.3
Condit. Reinf. active-inactive response ratio0.40.41.4-1.2-0.4-0.7-1.0-0.7-0.5-0.5-0.60.1-0.3-0.0
Condit. Reinf. active responses0.30.41.1-0.8-0.7-0.8-0.6-0.5-0.5-0.5-0.6-1.0-0.1-0.6
Condit. Reinf. inactive responses1.11.43.8-1.0-1.5-1.3-0.8-1.0-1.1-1.1-1.1-2.0-0.8-1.0
Condit. Reinf. lever presses0.30.31.40.10.30.30.10.00.11.00.20.41.01.2
Condit. Reinf. lever reinforcers received0.40.61.0-1.0-0.9-0.9-0.9-0.7-0.8-0.5-0.8-1.0-0.2-0.4
Pavlov. Cond. lever latency0.30.41.5-0.1-0.5-0.3-0.00.1-0.0-1.1-0.1-0.8-0.8-1.2
Pavlov. Cond. magazine entry latency0.40.41.20.30.80.60.10.40.50.80.51.10.70.6
Pavlov. Cond. change in total contacts0.81.21.81.01.31.00.91.01.11.41.11.01.30.8
Pavlov. Cond. index score0.60.71.70.41.00.70.30.40.51.30.51.30.91.3
Pavlov. Cond. latency score0.70.91.90.51.10.80.30.40.61.40.61.41.01.4
Pavlov. Cond. lever contacts0.20.31.5-0.40.2-0.1-0.5-0.5-0.40.7-0.30.60.51.2
Pavlov. Cond. magazine entry number0.91.11.8-0.9-1.1-1.0-0.7-1.1-1.2-1.3-1.2-1.1-1.0-0.7
Pavlov. Cond. intertrial magazine entries1.31.72.7-1.2-1.6-1.3-0.8-1.6-1.6-1.3-1.5-1.1-1.3-0.1
Pavlov. Cond. lever-magazine prob. diff.0.81.02.10.61.10.90.50.60.71.50.81.31.11.4
Pavlov. Cond. response bias0.10.20.6-0.40.1-0.1-0.4-0.4-0.30.6-0.20.40.40.8
Conditioned reinforcement - actives0.50.51.2-0.5-0.3-0.6-0.8-1.0-1.1-0.5-1.1-0.0-0.5-0.4
Conditioned reinforcement - inactives0.30.40.9-0.50.1-0.4-1.0-0.9-0.9-0.1-0.90.5-0.4-0.1
Conditioned locomotion0.10.10.2-0.1-0.1-0.1-0.1-0.4-0.4-0.1-0.40.3-0.2-0.1
Intermittent access intake day 1-15 change1.11.12.3-1.3-0.7-0.7-0.7-0.9-1.1-1.1-1.1-1.3-0.7-1.5
Intermittent access intake escalation0.90.92.7-1.1-0.4-0.6-0.6-0.7-0.9-1.1-1.0-1.1-0.7-1.6
Intermittent access intake escalation 20.30.30.6-0.4-0.2-0.3-0.8-0.7-0.8-0.4-0.8-0.30.0-0.7
Intermitt. access day 1 inactive lever presses1.81.93.9-1.1-2.0-1.6-1.8-1.7-1.6-0.9-1.6-0.9-0.80.3
Intermitt. access day 15 inactive lever presses1.71.92.9-1.7-1.0-1.2-1.3-1.1-1.2-1.7-1.3-0.9-1.7-1.7
Intermitt. access escalation Index0.80.84.60.9-1.1-0.6-0.4-0.3-0.01.00.00.20.52.1
Intermittent access day 1 total infusions0.91.01.9-1.3-0.4-0.9-1.2-1.4-1.3-0.9-1.3-0.1-1.1-0.0
Intermittent access day 15 total infusions2.12.43.4-1.8-0.9-1.4-1.6-1.6-1.8-1.5-1.8-1.3-1.4-1.5
Intermittent access terminal intake (last 3 days)2.02.23.1-1.7-1.0-1.4-1.6-1.6-1.7-1.3-1.8-1.4-1.2-1.6
Intermittent access total infusions1.31.52.5-1.5-0.8-1.1-1.4-1.6-1.6-0.9-1.6-0.6-1.1-0.4
Intermittent access day 1 locomotion1.71.83.1-1.8-1.3-1.2-0.9-1.1-1.2-1.4-1.2-1.4-1.7-1.2
Intermittent access day 15 total locomotion1.01.11.8-1.3-0.9-1.0-1.2-1.0-1.0-0.9-1.1-1.0-0.9-0.8
Intermittent access total locomotion1.71.92.5-1.6-1.5-1.3-1.4-1.5-1.6-1.3-1.6-1.2-1.4-0.8
Intermittent access standard deviation1.01.13.5-1.2-0.2-0.5-0.9-0.9-1.1-1.4-1.1-0.7-0.5-1.9
Cocaine induced anxiety1.21.42.31.30.51.31.51.31.31.21.30.71.50.6
Post-drug Anxiety4.95.47.72.71.92.42.62.42.42.52.41.92.81.1
Baseline Anxiety1.71.82.81.51.61.10.81.01.11.71.21.31.51.5
Lifetime Intake0.91.02.0-1.3-0.6-0.9-1.2-1.4-1.4-0.7-1.3-0.2-0.9-0.2
Incentive Sensitization - Responses0.10.10.30.30.1-0.1-0.20.20.20.50.2-0.10.0-0.1
Incentive Sensitization - Breakpoint0.10.10.20.2-0.1-0.3-0.40.10.10.40.1-0.3-0.1-0.1
Progressive ratio test 1 active lever presses1.71.73.2-1.3-1.3-1.3-1.6-1.8-1.6-1.0-1.6-0.3-1.30.4
Progressive ratio test 1 breakpoint1.91.93.1-1.5-1.3-1.4-1.7-1.8-1.6-1.2-1.6-0.5-1.50.1
Progressive ratio test 1 inactive lever presses1.92.02.9-1.7-1.3-1.5-1.7-1.6-1.5-1.2-1.5-0.6-1.7-0.5
Progressive ratio test 2 active lever presses0.91.01.8-0.9-1.2-1.2-1.3-1.3-1.1-0.4-1.1-0.6-0.80.2
Progressive ratio test 2 breakpoint1.21.32.3-1.0-1.4-1.4-1.5-1.5-1.3-0.6-1.3-0.8-0.90.1
Progressive ratio test 2 inactive lever presses1.92.23.4-1.7-1.4-1.6-1.8-1.8-1.7-1.1-1.7-0.9-1.3-0.3
Total sessions with >9 infusions0.40.40.9-1.0-0.1-0.2-0.7-0.8-0.6-0.5-0.60.9-0.60.7
Short access day 1 total inactive lever presses0.40.41.4-0.40.2-0.0-0.6-0.8-0.60.2-0.61.2-0.31.0
Short access day 10 total inactive lever presses0.30.31.6-0.1-0.6-0.3-0.4-0.5-0.20.2-0.20.8-0.11.3
Short access day 1 total infusions0.10.10.4-0.40.50.1-0.1-0.00.00.00.00.7-0.30.1
Short access day 10 total infusions1.11.22.3-1.5-0.2-0.7-0.6-1.0-1.1-1.4-1.1-0.4-1.4-1.5
Short access total infusions0.10.10.3-0.50.2-0.0-0.3-0.5-0.4-0.2-0.40.5-0.30.2
Short access day 1 locomotion1.11.23.6-1.4-0.3-0.7-0.6-0.3-0.5-1.5-0.6-0.9-1.7-1.9
Short access day 10 total locomotion0.91.02.3-1.4-0.5-0.7-0.1-0.5-0.7-1.4-0.7-0.7-1.3-1.5
Short access total locomotion0.80.82.2-1.50.0-0.4-0.3-0.6-0.7-1.3-0.7-0.1-1.4-1.3
Compulsive drug intake0.40.41.10.60.50.50.70.80.81.00.70.30.60.3
One hour access (0.3 mA shock)0.10.10.5-0.00.2-0.3-0.7-0.4-0.40.0-0.40.20.1-0.6
One hour access (shock baseline)0.10.10.40.10.30.0-0.4-0.1-0.10.1-0.10.20.4-0.6
Number of responses in last shaping day0.50.53.3-0.90.5-0.00.40.40.1-0.90.1-0.1-0.6-1.8
Context. condit. distance diff. score0.50.61.40.70.50.90.80.60.70.60.71.20.90.4
Locomotion velocity, session 11.31.42.3-1.4-1.1-1.3-1.2-0.8-0.9-1.4-0.9-1.5-1.5-0.8
Locomotion distance, session 13.03.86.0-2.2-1.3-1.7-2.3-2.0-2.1-2.4-2.1-1.5-2.4-1.1
Locomotion velocity, session 20.20.20.3-0.50.4-0.3-0.5-0.3-0.5-0.2-0.5-0.5-0.4-0.6
Locomotion distance, session 21.92.84.5-1.8-0.8-1.5-1.8-1.8-1.9-2.0-1.9-1.0-2.1-1.2
Locomotion velocity, session 32.83.24.2-2.0-1.2-1.8-2.0-1.9-2.0-1.9-2.0-1.4-2.1-1.1
Locomotion distance, session 33.53.86.1-2.4-1.7-1.9-2.1-2.5-2.3-2.0-2.2-0.9-2.00.2
Stereotopy head waving bouts, day 30.50.61.01.00.70.91.01.00.90.50.80.20.5-0.5
Stereotopy head waving duration, day 30.20.21.20.40.20.40.50.60.40.00.4-0.4-0.1-1.1
Locomotion velocity, session 70.20.20.5-0.5-0.5-0.5-0.1-0.3-0.2-0.7-0.2-0.3-0.7-0.0
Locomotion distance, session 71.62.14.0-1.6-1.7-1.6-1.4-1.4-1.4-2.0-1.4-0.9-1.5-0.5
Stereotopy head waving bouts, day 71.21.31.91.21.01.11.41.21.21.41.20.91.00.9
Stereotopy head waving duration, day 72.42.94.91.91.41.71.91.71.82.21.81.11.71.6
Locomotion velocity, session 80.20.30.50.40.70.40.70.60.50.70.50.40.3-0.1
Locomotion distance, session 80.50.71.3-1.0-0.2-0.4-0.8-1.1-1.1-1.0-1.10.3-0.9-0.4
Degree of sensitization distance0.30.31.00.5-0.10.20.60.80.7-0.10.6-0.30.3-1.0
Degree of sensitization stereotypy1.21.32.51.20.71.01.21.01.11.61.10.71.11.4
Condit. Reinf. active minus inactive responses0.30.41.4-0.6-0.1-0.6-0.3-0.3-0.5-0.7-0.5-0.3-0.8-1.2
Condit. Reinf. active-inactive response ratio0.10.10.30.10.60.20.30.30.20.10.20.40.1-0.2
Condit. Reinf. active responses1.01.21.8-1.3-0.8-1.2-1.0-1.0-1.1-1.3-1.1-0.5-1.3-1.3
Condit. Reinf. inactive responses3.64.35.6-2.3-2.1-2.2-2.2-2.0-2.1-2.4-2.1-1.3-2.2-1.5
Incentive salience index mean0.10.11.1-0.10.1-0.10.10.1-0.0-0.3-0.1-0.2-0.3-1.1
Condit. Reinf. lever presses0.20.31.90.40.40.20.40.60.3-0.00.2-0.30.2-1.4
Time in familiar zone, hab. session 10.20.20.4-0.4-0.1-0.2-0.6-0.4-0.4-0.6-0.40.1-0.4-0.3
Time in novel zone, hab. session 10.10.10.30.1-0.4-0.00.50.30.30.40.3-0.50.20.1
Total zone transitions, hab. session 10.30.51.2-0.8-0.4-0.5-0.5-0.6-0.7-1.1-0.7-0.5-0.9-0.7
Total locomotion distance, hab. session 10.10.10.3-0.10.30.10.0-0.2-0.3-0.5-0.30.2-0.5-0.5
Locomotion velocity, hab. session 10.00.10.2-0.10.40.20.1-0.1-0.2-0.3-0.10.5-0.4-0.1
Time in familiar zone, hab. session 20.10.10.60.30.20.2-0.00.10.10.20.20.80.70.3
Time in novel zone, hab. session 20.30.31.2-0.4-0.6-0.40.1-0.0-0.1-0.3-0.2-1.1-0.7-0.7
Total zone transitions, hab. session 20.20.30.9-0.60.3-0.1-0.4-0.4-0.4-1.0-0.40.0-0.8-0.5
Total locomotion distance, hab. session 20.20.30.7-0.80.3-0.2-0.4-0.6-0.6-0.8-0.60.3-0.8-0.2
Locomotion velocity, hab. session 20.10.20.5-0.50.60.0-0.2-0.4-0.3-0.6-0.30.5-0.7-0.1
Novel to familiar place preference ratio0.50.50.90.70.60.50.90.90.90.90.9-0.00.6-0.0
Novelty place preference0.20.20.50.40.30.20.60.70.60.50.6-0.30.3-0.3
Time in novel zone, NPP test0.10.20.30.40.10.10.50.60.50.40.4-0.40.2-0.3
Total zone transitions, NPP test1.01.43.0-1.3-0.4-0.8-1.2-1.2-1.3-1.7-1.3-0.5-1.6-0.7
Total locomotion distance, NPP test2.33.25.4-2.1-1.0-1.6-1.9-2.0-2.0-2.2-2.0-1.0-2.3-0.8
Locomotion velocity, NPP test1.42.03.7-1.7-0.5-1.1-1.4-1.5-1.6-1.8-1.5-0.6-1.9-0.8
Pavlov. Cond. lever latency0.20.21.6-0.0-0.10.20.10.00.30.10.30.70.21.3
Pavlov. Cond. magazine entry latency0.10.20.70.20.40.60.0-0.1-0.10.3-0.00.80.70.2
Pavlov. Cond. change in total contacts0.20.21.7-0.1-0.2-0.3-0.10.1-0.1-0.3-0.2-0.60.0-1.3
Pavlov. Cond. index score0.20.20.60.60.50.60.40.40.30.60.30.20.8-0.2
Pavlov. Cond. latency score0.10.10.30.50.40.40.30.30.20.40.20.00.5-0.6
Pavlov. Cond. lever contacts0.40.51.6-0.4-0.4-0.7-0.5-0.5-0.7-0.5-0.7-0.9-0.6-1.3
Pavlov. Cond. magazine entry number0.10.10.3-0.2-0.3-0.5-0.1-0.00.0-0.3-0.0-0.5-0.6-0.1
Pavlov. Cond. intertrial magazine entries0.70.81.4-1.0-0.7-0.9-0.8-0.8-0.9-1.1-0.9-0.6-1.2-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.51.00.91.00.80.80.71.10.70.61.20.1
Pavlov. Cond. response bias0.00.00.10.10.20.2-0.1-0.2-0.20.2-0.20.30.4-0.2
Bone: apparent density7.011.515.23.43.93.63.43.43.43.43.53.63.61.7
Bone surface8.014.017.94.13.94.04.24.24.13.54.13.13.71.2
Bone volume5.28.810.73.23.33.23.23.23.22.73.22.73.10.9
Bone: connectivity density5.28.210.93.03.33.12.93.02.92.93.02.73.01.1
Bone: cortical apparent density1.21.65.1-0.8-0.6-1.0-0.6-0.7-1.0-1.3-1.1-1.7-1.6-2.3
Bone: cortical area8.112.214.83.53.83.83.83.73.83.43.83.23.51.7
Bone: cortical porosity1.61.72.6-1.4-1.6-1.3-1.4-1.6-1.5-1.3-1.5-1.0-1.1-0.1
Bone: cortical porosity1.61.72.7-1.3-1.6-1.3-1.3-1.7-1.6-1.3-1.6-1.0-1.1-0.1
Bone: cortical thickness3.96.410.32.43.22.92.72.52.52.52.52.52.41.3
Bone: cortical thickness0.40.52.10.11.40.80.30.20.30.10.31.30.50.0
Bone: cortical tissue density1.41.85.4-0.9-0.7-1.1-0.7-0.8-1.1-1.4-1.2-1.8-1.7-2.3
Bone: elastic displacement2.83.25.5-1.9-2.0-1.8-2.2-2.3-2.1-1.4-2.0-0.9-1.41.0
Bone: elastic work0.20.21.10.20.20.3-0.2-0.2-0.10.6-0.00.70.61.1
Bone: endosteal estimation5.411.716.53.82.73.53.94.04.13.34.02.33.61.5
Bone: endosteal perimeter5.010.414.23.52.73.43.53.73.83.13.72.63.21.6
Bone: final force7.812.816.13.93.83.84.04.03.93.53.92.93.51.0
Bone: final moment7.913.016.33.93.83.94.04.03.93.53.93.03.60.9
Bone: marrow area5.511.916.73.82.63.53.94.04.13.34.12.33.61.6
Bone: maximum diameter3.46.28.62.62.22.72.72.92.92.52.91.72.51.3
Bone: maximum force9.616.621.24.44.24.34.54.64.54.14.53.34.11.2
Bone: maximum moment9.516.621.14.44.24.34.54.64.54.04.53.34.11.1
Bone: minimum diameter5.810.713.83.43.13.53.53.63.73.13.72.73.41.7
Bone: periosteal estimation9.118.524.04.54.04.64.84.84.94.14.93.44.42.1
Bone: periosteal perimeter8.714.417.83.83.94.13.94.14.23.74.23.63.71.8
Bone: post-yield work6.58.812.43.52.53.13.43.53.43.03.41.92.90.8
Bone: stiffness11.117.623.34.54.14.44.64.84.84.24.73.34.31.1
Bone: tissue strength0.30.30.50.70.30.40.50.70.60.70.6-0.30.6-0.3
Bone: trabecular number4.16.410.22.53.22.72.42.42.52.52.52.92.61.1
Bone: trabecular spacing1.51.95.1-1.2-2.2-1.4-1.0-1.1-1.1-1.4-1.1-2.3-1.2-0.5
Bone: trabecular thickness0.40.40.8-0.70.2-0.4-0.9-0.8-0.8-0.7-0.80.7-0.4-0.3
Bone: trabecular tissue density0.40.61.8-0.5-0.5-0.7-0.3-0.3-0.5-0.8-0.6-1.3-1.0-1.3
Breakpoint value in progressive ratio session1.51.76.01.40.61.20.70.50.91.30.91.61.52.4
Distance traveled before self-admin0.60.71.5-0.6-0.9-1.0-1.0-1.1-0.8-0.3-0.80.0-0.71.2
Distance traveled after self-admin1.01.14.10.90.41.00.40.00.21.10.31.91.22.0
Delta time in closed arm before/after self-admin0.10.10.2-0.00.10.20.20.30.20.10.20.40.1-0.4
Delta time in open arm before/after self-admin2.42.34.1-1.2-1.5-1.7-2.0-1.8-1.7-1.4-1.7-1.1-1.7-0.2
Diff in mean of infusions in LGA sessions1.01.12.01.11.41.40.91.00.90.61.01.21.30.1
Extinction: sum of active levers before priming1.61.64.81.30.81.00.50.81.11.41.11.51.42.2
Active lever presses in extinction session 60.30.31.30.10.30.40.40.40.60.20.61.10.11.0
Delta distance traveled before/after self-admin0.70.71.50.60.71.20.90.60.60.90.61.11.10.7
Delta ambulatory time before/after self-admin0.40.50.90.50.51.00.90.50.50.80.50.71.00.5
Time in closed arm before self-admin0.30.41.00.20.70.41.00.80.7-0.20.6-0.0-0.3-0.9
Time in closed arm after self-admin0.10.10.5-0.3-0.2-0.20.30.20.3-0.30.30.1-0.70.0
Time in open arm before self-admin0.40.41.00.30.30.60.70.90.90.70.9-0.01.00.0
Time in open arm after self-admin0.60.71.4-0.6-0.6-0.7-1.0-0.5-0.6-0.9-0.7-1.1-0.7-1.2
Sum of active levers in priming session hrs 5-60.10.10.30.4-0.3-0.1-0.2-0.2-0.10.1-0.1-0.50.30.4
Time to tail flick, vehicle, before self-admin0.30.40.90.1-0.1-0.5-0.8-0.9-0.8-0.2-0.80.6-0.10.6
Time to tail flick, vehicle, after self-admin0.00.10.3-0.1-0.5-0.2-0.5-0.1-0.0-0.0-0.0-0.20.1-0.1
Time to tail flick, test, before self-admin0.60.61.5-1.0-0.3-0.9-1.2-1.1-0.9-0.5-0.90.3-0.70.2
Time to tail flick, test, after self-admin0.30.31.5-0.2-0.7-0.60.20.30.1-0.50.1-1.0-0.2-1.2
Delta time to tail flick, vehicle, before/after SA0.20.20.60.4-0.10.30.20.50.50.80.50.00.70.2
Delta time to tail flick, test, before/after SA0.90.83.80.2-0.5-0.20.80.70.4-0.60.3-1.6-0.2-2.0
Ambulatory time before self-admin2.62.74.4-1.6-1.8-1.9-1.9-2.1-1.8-1.3-1.7-0.6-1.71.2
Ambulatory time after self-admin0.91.06.20.1-0.60.1-0.5-0.9-0.60.5-0.51.30.42.5
Total heroin consumption2.83.44.41.81.42.02.01.81.91.92.01.62.11.7
Area under the delay curve0.90.92.30.81.51.01.11.11.00.21.00.90.3-0.8
Delay disc. indifference point, 0s delay0.60.61.30.41.10.81.21.11.0-0.11.00.5-0.1-0.4
Delay disc. indifference point, 16s delay1.11.11.71.01.21.11.31.31.20.71.10.80.7-0.5
Delay disc. indifference point, 2s delay0.40.51.90.40.80.20.80.80.6-0.40.60.1-0.5-1.4
Delay disc. indifference point, 24s delay0.70.71.20.80.80.81.01.11.10.61.10.50.70.0
Delay disc. indifference point, 4s delay0.30.31.70.40.80.40.40.60.4-0.30.30.4-0.1-1.3
Delay disc. indifference point, 8s delay2.52.64.41.32.11.92.01.91.81.01.81.51.1-0.0
Delay discount exponential model param0.70.72.0-0.8-1.4-0.9-0.9-1.0-0.9-0.2-0.9-0.8-0.30.8
Delay discount hyperbolic model param0.60.71.8-0.7-1.3-0.8-0.9-1.0-0.8-0.1-0.8-0.7-0.11.0
Fecal boli incidents, locomotor time 10.30.40.7-0.40.6-0.1-0.1-0.7-0.8-0.7-0.80.4-0.5-0.8
Change in fecal boli incidents, locomotor task0.20.20.60.3-0.2-0.10.10.70.80.70.7-0.30.30.3
Time >=10cm from walls, locomotor time 11.41.43.11.01.71.21.10.80.91.11.01.80.61.4
Bouts of movement, locomotor time 10.20.20.90.40.90.80.60.50.40.10.4-0.20.2-0.4
Total resting periods, locomotor time 10.10.10.4-0.10.40.20.0-0.1-0.2-0.4-0.2-0.4-0.1-0.6
Rest time, locomotor task time 10.10.10.70.1-0.4-0.0-0.6-0.3-0.1-0.1-0.1-0.30.50.8
Distance moved, locomotor task time 10.30.31.7-0.20.20.10.2-0.4-0.20.2-0.11.1-0.41.3
Vertical activity count, locomotor time 11.61.74.41.01.81.41.31.01.11.21.12.10.61.1
Time >=10cm from walls, locomotor time 20.20.21.5-0.00.10.1-0.3-0.5-0.30.2-0.20.80.01.2
Bouts of movement, locomotor time 22.32.43.61.31.21.71.81.91.91.51.90.81.90.5
Total resting periods, locomotor time 22.02.23.61.11.11.61.81.91.91.31.80.51.70.2
Rest time, locomotor task time 20.20.20.90.3-0.0-0.10.10.40.3-0.00.2-1.00.1-0.9
Distance moved, locomotor task time 20.60.74.30.20.10.2-0.5-0.6-0.30.5-0.21.40.52.1
Vertical activity count, locomotor time 20.60.71.40.90.60.80.50.50.70.90.71.10.81.2
Weight adjusted by age1.01.12.70.41.61.11.21.41.20.21.10.60.2-1.1
Seeking ratio, delayed vs. immediate footshock0.10.20.40.40.70.30.40.50.40.10.40.30.2-0.5
Locomotion in novel chamber0.30.30.70.70.60.50.60.90.80.20.80.00.2-0.3
Locomotion in novel chamber post-restriction0.50.61.41.00.60.61.21.00.90.60.8-0.30.6-0.1
Progressive ratio0.10.10.80.20.30.2-0.10.00.20.20.20.50.40.9
Food seeking constrained by brief footshock1.41.75.91.00.81.20.70.30.61.80.71.71.52.4
Seeking ratio, punishment vs. effort0.10.10.40.30.00.30.50.30.20.60.20.20.40.0
Run reversals in cocaine runway, females0.50.52.1-0.7-0.8-0.6-0.9-0.8-0.5-0.2-0.40.0-0.61.4
Run reversals in cocaine runway, males2.01.94.8-1.1-0.1-1.1-1.1-1.0-1.3-1.4-1.3-1.2-2.2-2.2
Latency to leave start box in cocaine runway0.40.41.3-0.3-0.5-0.5-0.0-0.1-0.2-0.7-0.2-1.1-1.1-1.0
Latency to leave start box in cocaine runway, F1.92.13.8-1.2-1.4-1.5-1.4-1.4-1.4-1.5-1.4-1.5-2.0-0.8
Latency to leave start box in cocaine runway, M1.51.43.01.21.01.21.71.51.51.11.40.40.90.1
Cd content in liver1.31.43.8-1.0-0.8-1.3-0.8-0.6-0.8-1.4-0.9-1.3-1.4-2.0
Co content in liver0.20.30.6-0.4-0.2-0.4-0.5-0.6-0.6-0.7-0.6-0.1-0.8-0.5
Cu content in liver1.72.13.11.40.71.41.31.31.51.51.61.41.71.8
Fe content in liver0.30.42.9-0.1-0.60.1-0.3-0.4-0.10.1-0.10.70.41.7
K content in liver1.01.01.91.01.41.01.11.21.10.71.11.10.6-0.1
Mg content in liver0.10.10.3-0.10.40.0-0.10.00.1-0.10.10.6-0.10.3
Mn content in liver0.20.21.00.40.20.30.10.50.3-0.00.3-0.20.3-1.0
Na content in liver0.30.31.10.2-0.10.30.20.40.60.70.60.60.81.0
Rb content in liver0.20.21.3-0.2-0.7-0.3-0.2-0.20.00.20.0-0.1-0.31.1
Se content in liver0.80.92.3-1.0-0.6-0.9-0.8-0.7-0.9-1.4-0.9-0.4-1.0-1.5
Sr content in liver0.80.71.01.00.30.81.01.01.00.91.00.30.90.4
Zn content in liver0.40.41.3-0.7-0.8-0.6-0.8-0.7-0.5-0.3-0.40.1-0.41.2