Hub : Genes

Mapkbp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000007018 0.22 0.09 1.2e-12 0.11 0.17 0.15 0.17 1.3e-06 2.8e-09 2.2e-08 2.0e-09
2 BLA mRNA stability ENSRNOG00000007018 0.06 0.04 7.2e-03 0.03 0.03 0.01 0.03 8.4e-03 1.0e-02 9.8e-02 1.5e-02
3 Brain gene expression ENSRNOG00000007018 0.71 0.01 0.0e+00 0.23 0.27 0.25 0.28 3.1e-21 4.5e-25 2.8e-23 8.7e-26
4 Brain mRNA stability ENSRNOG00000007018 0.08 0.04 1.3e-07 0.08 0.08 0.07 0.07 3.9e-08 6.8e-08 7.9e-07 2.3e-07
5 Eye mRNA stability ENSRNOG00000007018 0.52 0.16 1.1e-03 0.16 0.17 0.14 0.21 2.0e-03 1.2e-03 3.5e-03 3.5e-04
6 NAcc gene expression ENSRNOG00000007018 0.11 0.06 3.8e-05 0.07 0.05 0.06 0.04 5.9e-06 1.4e-04 3.3e-05 5.4e-04
7 NAcc mRNA stability ENSRNOG00000007018 0.16 0.09 1.2e-06 0.08 0.08 0.08 0.09 2.4e-06 1.1e-06 1.5e-06 6.4e-07
8 PL gene expression ENSRNOG00000007018 0.17 0.08 2.0e-10 0.09 0.1 0.08 0.11 3.5e-07 3.4e-08 7.0e-07 2.1e-08
9 PL mRNA stability ENSRNOG00000007018 0.11 0.08 1.9e-03 0.03 0.03 0.02 0.03 2.0e-03 1.6e-03 1.1e-02 4.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail4.514.618.84.34.03.94.02.23.44.34.33.4
BMI without tail4.49.215.84.03.23.03.2-0.43.23.43.22.2
Body weight5.121.627.95.15.05.05.12.14.04.75.34.5
Epididymis fat weight0.61.42.41.11.41.31.51.00.60.81.21.4
Glucose0.61.01.71.11.21.31.2-0.61.10.70.60.6
Heart weight6.79.612.73.43.63.43.50.72.82.53.53.3
Left kidney weight1.54.26.92.62.62.02.40.31.01.62.32.3
Right kidney weight2.26.310.33.23.02.12.91.31.12.12.92.9
Tail length0.41.32.91.41.01.11.1-1.71.40.80.90.6
Length with tail0.83.14.02.01.92.01.9-0.41.61.32.01.9
Length without tail0.92.03.31.01.41.51.31.80.71.21.71.8
Liver weight, left3.86.211.63.12.12.42.0-0.43.43.32.71.5
Liver weight, right0.91.52.71.61.20.91.30.60.81.41.61.1
Parametrial fat weight0.10.20.60.40.40.30.30.20.20.10.70.7
Retroperitoneal fat weight4.213.919.43.44.14.44.32.52.92.84.24.3
Intraocular pressure1.92.65.1-2.1-1.5-1.6-1.51.3-2.3-1.3-1.5-1.2
Extensor digitorum longus weight0.10.51.41.00.70.60.90.40.31.20.50.3
Soleus weight0.00.00.2-0.10.00.40.10.20.40.20.00.0
Tibialis anterior weight0.31.02.30.60.91.51.10.61.30.80.90.9
Tibia length0.51.43.70.71.30.81.31.7-0.5-0.11.21.9
Number of licking bursts0.50.51.50.1-0.7-0.5-0.7-0.90.70.7-0.6-1.2
Food consumed during 24 hour testing period0.30.41.80.3-0.4-0.2-0.4-1.30.80.4-0.2-0.7
Times rat made contact with spout0.30.31.00.30.60.30.61.0-0.30.30.50.5
Mean time between licks in bursts1.11.52.4-0.9-1.4-1.5-1.4-1.4-0.8-0.6-1.2-1.5
Mean num. licks in bursts0.91.02.50.21.20.91.21.3-0.6-0.41.01.6
Std. dev. time between licks in bursts0.80.91.61.21.00.61.00.90.21.31.10.8
Water consumed over 24 hours0.00.00.2-0.40.10.20.10.2-0.1-0.4-0.10.0
Indifference point 0 sec2.03.312.60.41.81.11.63.6-1.00.71.82.3
Indifference point AUC2.22.54.2-1.9-1.7-1.6-1.5-0.5-1.5-2.1-1.8-1.3
Indifference point function ln k3.44.87.62.82.32.22.2-0.12.32.82.21.5
Indifference point function log k3.44.87.62.82.32.22.2-0.12.32.82.21.5
Delay discounting total patch changes 0 sec1.82.911.90.31.71.01.43.5-1.00.61.62.1
Delay discounting total patch changes 12 sec0.81.13.4-1.00.2-0.00.31.9-1.5-1.30.01.0
Delay discounting total patch changes 18 sec0.71.02.5-1.5-0.5-0.7-0.50.7-1.5-1.6-0.7-0.0
Delay discounting total patch changes 24 sec1.01.22.90.91.10.61.01.70.10.81.61.4
Delay discounting total patch changes 6 sec0.50.82.3-1.1-0.1-0.2-0.11.5-1.4-1.1-0.40.5
Delay discounting time to switch 0 sec0.40.61.4-1.1-0.5-0.3-0.41.1-0.8-1.2-0.30.4
Delay discounting water rate 0 sec0.91.42.11.21.41.41.30.01.21.41.10.7
Delay discounting water rate 12 sec0.91.34.11.00.20.50.1-1.72.01.60.0-0.9
Delay discounting water rate 18 sec0.71.03.71.40.60.40.4-0.61.31.90.4-0.5
Delay discounting water rate 24 sec0.71.02.30.91.01.41.1-0.21.51.30.50.2
Delay discounting water rate 6 sec0.50.72.8-0.3-0.5-0.1-0.6-1.70.90.1-0.8-1.3
Locomotor activity0.20.30.5-0.6-0.7-0.7-0.70.1-0.6-0.5-0.3-0.4
Locomotor testing distance0.60.91.5-1.1-1.1-1.1-0.90.2-1.2-1.0-0.9-0.7
Locomotor testing rearing1.01.52.7-1.5-1.3-1.0-1.2-0.7-1.1-1.7-1.4-0.8
Light reinforcement 12.34.213.8-0.41.91.61.83.7-1.1-0.91.63.0
Light reinforcement 20.91.13.1-1.5-0.9-0.8-0.70.5-1.3-1.8-1.0-0.2
Reaction time number correct3.55.18.02.72.52.42.2-0.42.82.62.21.5
Reaction time mean minus median0.91.11.51.10.81.11.20.80.91.21.21.1
Reaction time mean minus median AUC2.53.14.81.91.71.92.21.21.31.72.01.9
Reaction time num false alarms0.10.10.8-0.30.3-0.00.0-0.1-0.3-0.9-0.20.3
Reaction time num false alarms AUC0.10.10.8-0.50.1-0.1-0.1-0.2-0.3-0.9-0.30.2
Reaction time trials correct on left3.55.18.02.72.52.42.2-0.42.82.62.21.5
Reaction time trials on left3.65.07.92.62.52.42.2-0.42.82.52.21.5
Reaction time mean0.20.31.0-1.0-0.6-0.3-0.60.2-0.2-0.4-0.6-0.3
Reaction time mean AUC0.10.10.4-0.6-0.3-0.1-0.30.4-0.1-0.1-0.2-0.1
Median of all reaction times1.01.43.3-1.8-1.3-1.0-1.4-0.1-0.8-1.2-1.3-1.0
Reaction time omissions0.30.41.30.00.60.50.61.0-0.4-0.20.51.2
Reaction time false alarm rate1.01.53.6-1.6-1.0-1.1-1.00.2-1.5-1.9-1.2-0.4
Reaction time premature initiation rate0.70.93.2-1.6-0.6-0.5-0.60.3-1.0-1.8-0.40.4
Reaction time premature initiations0.30.41.3-0.10.70.80.60.10.5-0.40.71.2
Std. dev. reaction times0.71.02.30.70.80.91.11.50.41.01.11.1
Reaction time trials completed3.65.07.92.62.52.42.2-0.42.82.52.21.5
Reaction time trials AUC3.65.18.32.62.62.52.2-0.42.92.52.21.6
Social response proportion1.31.44.0-0.11.21.81.20.31.0-0.80.82.0
Social responses0.70.93.4-1.70.10.4-0.00.7-0.8-1.8-0.50.8
Social time0.10.20.4-0.10.30.60.40.60.30.30.50.4
Conditioned locomotion2.42.94.12.01.91.91.9-0.01.71.51.71.6
Cocaine response after cond. corrected1.92.15.6-0.6-1.8-1.6-1.7-1.3-0.10.4-1.6-2.4
Cocaine response after cond. not corrected2.62.86.8-0.8-2.1-2.0-2.1-1.5-0.30.2-1.8-2.6
Cocaine response before conditioning0.20.31.0-0.5-0.3-0.6-0.4-0.0-0.9-1.0-0.30.1
Saline control response2.63.47.11.12.22.12.21.80.50.52.22.7
Condit. Reinf. active minus inactive responses1.82.34.00.91.62.01.60.71.60.51.82.0
Condit. Reinf. active-inactive response ratio1.31.32.40.81.21.61.20.41.30.51.31.4
Condit. Reinf. active responses2.43.35.81.02.12.42.01.21.60.62.12.4
Condit. Reinf. inactive responses1.51.83.50.41.51.61.51.90.60.31.51.9
Condit. Reinf. lever presses1.31.86.00.11.31.21.22.40.10.21.41.8
Condit. Reinf. lever reinforcers received2.13.06.10.71.92.21.91.41.40.32.02.5
Pavlov. Cond. lever latency4.15.69.7-1.4-2.8-2.7-2.8-2.6-0.9-0.8-2.5-3.1
Pavlov. Cond. magazine entry latency1.82.04.6-0.01.71.81.71.60.1-0.71.12.1
Pavlov. Cond. change in total contacts1.72.45.40.41.92.11.91.10.9-0.31.52.3
Pavlov. Cond. index score2.73.67.30.62.42.52.31.80.8-0.11.82.7
Pavlov. Cond. latency score2.32.96.00.52.22.32.11.50.7-0.21.62.4
Pavlov. Cond. lever contacts3.44.78.70.92.52.42.52.80.70.62.43.0
Pavlov. Cond. magazine entry number1.82.24.7-0.4-1.9-2.1-1.9-1.1-0.60.4-1.3-2.2
Pavlov. Cond. intertrial magazine entries0.20.31.40.7-0.2-0.5-0.20.0-0.01.20.0-0.7
Pavlov. Cond. lever-magazine prob. diff.2.63.36.90.52.32.42.31.80.7-0.21.72.6
Pavlov. Cond. response bias3.95.410.50.92.82.92.72.70.90.42.53.2
Conditioned reinforcement - actives0.20.20.5-0.4-0.1-0.1-0.10.5-0.6-0.70.20.6
Conditioned reinforcement - inactives0.20.20.80.30.30.60.2-0.90.6-0.00.10.2
Conditioned locomotion0.81.02.9-0.9-0.2-0.5-0.21.5-1.7-1.4-0.00.7
Intermittent access intake day 1-15 change0.80.72.60.90.20.3-0.0-1.61.31.0-0.0-0.8
Intermittent access intake escalation0.90.94.10.70.10.3-0.1-2.01.40.7-0.2-0.8
Intermittent access intake escalation 22.22.210.00.7-0.6-0.5-0.8-3.21.40.9-0.9-2.0
Intermitt. access day 1 inactive lever presses0.80.82.70.31.00.90.90.7-0.0-0.31.21.6
Intermitt. access day 15 inactive lever presses0.20.21.0-0.30.30.40.2-0.3-0.2-1.0-0.10.5
Intermitt. access escalation Index0.30.31.8-0.20.50.30.31.4-0.20.10.20.5
Intermittent access day 1 total infusions0.40.51.3-0.8-0.10.10.11.2-1.0-1.0-0.00.7
Intermittent access day 15 total infusions0.00.00.1-0.10.10.3-0.0-0.40.1-0.3-0.10.1
Intermittent access terminal intake (last 3 days)0.20.21.00.30.10.40.0-1.00.60.3-0.1-0.2
Intermittent access total infusions0.10.10.2-0.00.20.40.2-0.00.0-0.30.20.5
Intermittent access day 1 locomotion1.11.14.8-0.10.70.50.82.2-1.0-0.40.91.5
Intermittent access day 15 total locomotion0.70.81.50.80.81.20.8-0.71.20.30.81.0
Intermittent access total locomotion0.10.10.5-0.10.10.30.20.1-0.0-0.50.30.7
Intermittent access standard deviation0.40.51.50.70.30.5-0.0-1.21.10.70.3-0.2
Cocaine induced anxiety0.40.41.20.60.70.50.8-0.3-0.1-0.60.61.1
Post-drug Anxiety0.30.30.80.90.60.50.5-0.70.60.40.50.4
Baseline Anxiety0.30.31.20.50.40.50.3-0.10.81.10.3-0.2
Lifetime Intake0.10.10.2-0.5-0.4-0.2-0.30.3-0.5-0.4-0.20.0
Incentive Sensitization - Responses0.10.10.10.20.30.40.4-0.10.3-0.10.00.2
Incentive Sensitization - Breakpoint0.10.10.20.10.30.40.4-0.00.3-0.20.10.3
Progressive ratio test 1 active lever presses0.30.30.7-0.40.30.50.20.8-0.3-0.80.20.9
Progressive ratio test 1 breakpoint0.20.20.7-0.40.10.40.10.3-0.2-0.80.10.6
Progressive ratio test 1 inactive lever presses0.30.41.8-0.80.00.3-0.10.1-0.6-1.3-0.10.6
Progressive ratio test 2 active lever presses0.30.31.7-0.8-0.10.3-0.0-0.1-0.2-1.3-0.30.5
Progressive ratio test 2 breakpoint0.30.41.4-0.70.20.60.30.4-0.2-1.2-0.10.9
Progressive ratio test 2 inactive lever presses0.20.20.5-0.10.40.60.5-0.2-0.0-0.70.10.7
Total sessions with >9 infusions0.70.72.4-0.7-0.5-0.8-0.51.4-1.5-0.7-0.20.1
Short access day 1 total inactive lever presses0.20.30.60.60.50.50.4-0.00.30.70.80.5
Short access day 10 total inactive lever presses1.41.63.11.11.21.41.3-1.81.2-0.50.91.5
Short access day 1 total infusions1.01.11.9-1.1-1.2-1.2-1.20.4-1.4-0.8-0.9-0.8
Short access day 10 total infusions0.30.31.3-0.10.10.30.21.1-0.4-0.10.60.9
Short access total infusions0.20.30.8-0.6-0.6-0.4-0.50.9-0.7-0.1-0.1-0.1
Short access day 1 locomotion0.50.61.2-1.1-0.6-0.5-0.60.9-1.1-0.9-0.40.1
Short access day 10 total locomotion0.40.51.20.2-0.9-1.0-0.7-0.5-0.30.3-0.5-1.1
Short access total locomotion0.50.62.8-0.4-0.0-0.10.11.7-1.0-0.50.40.8
Compulsive drug intake0.20.21.00.20.00.3-0.1-0.61.00.7-0.1-0.5
One hour access (0.3 mA shock)0.50.63.00.20.00.5-0.1-1.71.1-0.2-0.4-0.5
One hour access (shock baseline)0.20.31.5-0.50.00.1-0.0-0.0-0.6-1.2-0.30.4
Number of responses in last shaping day0.60.62.0-0.9-0.6-0.7-0.61.1-1.4-0.4-0.4-0.1
Context. condit. distance diff. score2.32.84.61.72.02.22.0-1.01.91.01.41.5
Locomotion velocity, session 14.24.57.3-2.1-2.3-2.7-2.3-0.6-2.4-2.0-2.2-1.9
Locomotion distance, session 11.82.43.3-1.4-1.6-1.8-1.6-1.0-1.6-1.7-1.6-1.3
Locomotion velocity, session 20.20.20.80.90.1-0.30.2-0.0-0.00.80.2-0.2
Locomotion distance, session 20.60.82.3-0.4-0.9-1.0-0.9-1.5-0.2-0.7-1.0-1.0
Locomotion velocity, session 30.40.40.9-0.2-0.5-0.9-0.50.3-0.90.4-0.7-0.9
Locomotion distance, session 30.40.41.3-0.3-0.2-0.3-0.3-0.9-0.3-0.2-1.1-1.1
Stereotopy head waving bouts, day 32.12.53.91.41.81.41.82.00.21.31.81.8
Stereotopy head waving duration, day 32.53.04.81.81.71.21.72.00.42.12.21.7
Locomotion velocity, session 70.20.20.50.20.60.40.6-0.7-0.2-0.4-0.40.1
Locomotion distance, session 70.30.42.5-0.00.30.50.3-1.60.6-0.6-0.30.0
Stereotopy head waving bouts, day 70.20.31.6-0.10.30.30.31.3-0.20.10.40.6
Stereotopy head waving duration, day 70.30.42.9-0.5-0.0-0.1-0.01.7-0.7-0.00.00.2
Locomotion velocity, session 80.91.12.31.51.40.91.4-0.10.61.01.01.0
Locomotion distance, session 80.81.23.41.11.11.11.2-1.81.30.20.50.7
Degree of sensitization distance0.20.20.7-0.40.20.50.2-0.10.4-0.60.50.8
Degree of sensitization stereotypy0.20.30.7-0.8-0.2-0.1-0.30.7-0.6-0.7-0.5-0.1
Condit. Reinf. active minus inactive responses0.70.82.5-1.20.10.20.11.2-0.9-1.6-0.20.8
Condit. Reinf. active-inactive response ratio0.60.71.90.10.90.80.91.4-0.1-0.10.61.1
Condit. Reinf. active responses1.21.56.0-2.0-0.3-0.1-0.30.9-1.2-2.4-0.70.6
Condit. Reinf. inactive responses1.11.34.9-1.8-0.8-0.5-0.8-0.4-0.8-2.2-1.2-0.2
Incentive salience index mean1.21.55.2-1.9-0.6-0.5-0.61.0-1.3-2.3-0.80.4
Condit. Reinf. lever presses1.01.34.6-1.7-0.7-0.7-0.70.8-1.2-2.1-0.70.3
Time in familiar zone, hab. session 11.31.22.5-0.8-1.6-1.2-1.5-0.9-0.0-0.0-1.0-1.6
Time in novel zone, hab. session 12.12.14.00.92.01.72.01.30.10.21.31.9
Total zone transitions, hab. session 10.40.51.1-0.5-1.1-1.1-1.0-0.6-0.0-0.1-0.4-0.7
Total locomotion distance, hab. session 10.30.41.0-0.5-0.9-1.0-0.9-0.5-0.3-0.4-0.4-0.5
Locomotion velocity, hab. session 10.50.71.6-0.8-1.2-1.3-1.1-0.4-0.6-0.7-0.5-0.6
Time in familiar zone, hab. session 20.10.10.5-0.1-0.1-0.1-0.00.60.30.70.2-0.2
Time in novel zone, hab. session 20.30.30.70.60.80.70.80.0-0.2-0.30.30.8
Total zone transitions, hab. session 20.30.41.20.2-0.8-0.8-0.8-1.10.30.3-0.3-0.8
Total locomotion distance, hab. session 20.00.00.20.2-0.1-0.0-0.1-0.40.3-0.00.20.2
Locomotion velocity, hab. session 20.00.00.1-0.0-0.3-0.2-0.3-0.30.1-0.10.10.1
Novel to familiar place preference ratio1.92.03.71.01.61.61.61.50.30.51.61.9
Novelty place preference1.71.83.50.91.61.51.61.40.20.41.51.9
Time in novel zone, NPP test1.61.73.40.91.51.51.61.30.30.41.51.8
Total zone transitions, NPP test1.42.05.0-0.4-1.6-1.6-1.6-2.2-0.0-0.2-1.4-1.9
Total locomotion distance, NPP test0.50.73.10.1-0.8-1.0-0.7-1.8-0.2-0.2-0.7-0.9
Locomotion velocity, NPP test0.60.93.00.1-0.9-1.1-0.9-1.7-0.3-0.2-0.8-1.1
Pavlov. Cond. lever latency0.20.31.00.60.40.60.50.00.71.00.3-0.2
Pavlov. Cond. magazine entry latency1.21.64.7-0.21.21.11.31.5-0.5-1.40.92.2
Pavlov. Cond. change in total contacts0.40.41.10.30.50.50.5-1.00.5-0.70.20.7
Pavlov. Cond. index score0.30.41.7-0.7-0.1-0.2-0.10.6-0.7-1.3-0.10.7
Pavlov. Cond. latency score0.30.41.3-0.6-0.0-0.3-0.00.8-0.8-1.10.10.8
Pavlov. Cond. lever contacts0.30.41.2-0.6-0.5-0.7-0.5-0.1-0.7-1.1-0.40.1
Pavlov. Cond. magazine entry number0.80.92.80.2-0.9-0.8-1.0-1.10.51.2-0.6-1.7
Pavlov. Cond. intertrial magazine entries0.30.41.3-0.2-0.5-0.1-0.5-0.60.70.8-0.4-1.1
Pavlov. Cond. lever-magazine prob. diff.0.30.41.8-0.7-0.3-0.4-0.30.2-0.7-1.3-0.30.4
Pavlov. Cond. response bias0.30.42.2-0.60.10.10.1-0.1-0.4-1.5-0.20.7
Bone: apparent density0.81.42.71.61.01.01.0-0.21.41.61.20.6
Bone surface1.01.82.91.51.31.41.30.11.71.71.40.9
Bone volume1.01.72.91.51.31.41.40.31.41.71.30.8
Bone: connectivity density0.50.81.50.80.80.80.80.60.90.81.21.0
Bone: cortical apparent density0.40.51.3-1.1-0.8-0.3-0.7-0.1-0.2-0.7-0.8-0.8
Bone: cortical area1.62.43.11.71.71.61.81.01.11.71.61.4
Bone: cortical porosity1.51.62.7-0.3-1.5-1.6-1.4-1.6-0.7-0.3-1.3-1.7
Bone: cortical porosity0.30.30.70.2-0.6-0.8-0.5-0.7-0.50.0-0.5-0.7
Bone: cortical thickness0.91.52.21.51.41.21.40.60.81.41.21.1
Bone: cortical thickness0.60.72.50.7-0.3-0.1-0.3-0.81.11.6-0.0-1.0
Bone: cortical tissue density0.40.51.3-1.1-0.8-0.4-0.8-0.1-0.2-0.6-0.8-0.8
Bone: elastic displacement0.30.31.1-0.5-0.4-0.5-0.30.7-1.1-0.6-0.4-0.2
Bone: elastic work0.60.83.20.30.90.71.01.8-0.40.40.71.0
Bone: endosteal estimation0.10.20.70.50.30.40.2-0.70.80.60.2-0.1
Bone: endosteal perimeter0.00.00.00.10.10.10.0-0.20.20.1-0.0-0.1
Bone: final force0.91.43.00.91.71.71.70.20.90.40.91.3
Bone: final moment0.61.02.20.71.51.51.50.30.60.30.71.1
Bone: marrow area0.10.30.70.60.40.50.3-0.60.90.60.3-0.0
Bone: maximum diameter0.91.72.21.31.51.51.40.71.21.41.41.2
Bone: maximum force1.62.74.61.62.12.02.10.80.91.01.71.9
Bone: maximum moment1.22.03.51.31.91.71.90.80.70.81.41.7
Bone: minimum diameter0.61.12.21.41.00.61.01.10.21.51.20.8
Bone: periosteal estimation0.61.31.81.31.31.21.30.31.01.41.10.8
Bone: periosteal perimeter0.40.61.01.00.90.70.90.60.30.90.80.7
Bone: post-yield work0.20.31.90.3-0.3-0.3-0.3-1.40.3-0.1-0.2-0.3
Bone: stiffness1.22.03.01.41.71.71.70.21.20.81.51.6
Bone: tissue strength0.10.10.20.50.50.30.4-0.3-0.0-0.10.30.5
Bone: trabecular number1.93.05.52.21.61.81.6-0.82.32.01.71.0
Bone: trabecular spacing1.72.25.6-1.9-0.7-1.0-0.82.3-2.4-1.6-0.9-0.1
Bone: trabecular thickness0.30.41.00.0-0.7-0.3-0.6-1.00.80.5-0.4-0.9
Bone: trabecular tissue density3.14.416.0-0.6-2.0-1.6-2.1-4.00.6-0.7-2.1-2.6
Breakpoint value in progressive ratio session0.30.31.30.5-0.10.20.1-0.50.91.10.1-0.4
Distance traveled before self-admin0.30.30.60.60.50.50.50.40.50.60.80.5
Distance traveled after self-admin0.30.31.00.50.30.50.3-0.21.00.90.50.0
Delta time in closed arm before/after self-admin0.20.20.8-0.30.20.50.3-0.7-0.0-0.9-0.30.4
Delta time in open arm before/after self-admin2.72.66.22.11.41.71.4-1.22.51.71.20.6
Diff in mean of infusions in LGA sessions0.10.10.4-0.20.20.40.40.2-0.0-0.40.10.6
Extinction: sum of active levers before priming1.01.01.7-1.0-1.3-1.2-1.2-0.0-0.9-0.4-1.1-1.2
Active lever presses in extinction session 60.10.10.30.2-0.4-0.6-0.3-0.5-0.30.2-0.3-0.5
Delta distance traveled before/after self-admin0.10.10.1-0.4-0.3-0.2-0.3-0.20.1-0.2-0.3-0.3
Delta ambulatory time before/after self-admin0.20.20.5-0.7-0.3-0.2-0.30.2-0.4-0.7-0.30.1
Time in closed arm before self-admin1.61.83.1-1.8-1.5-1.5-1.60.6-1.4-1.0-1.3-1.2
Time in closed arm after self-admin1.21.23.5-1.9-0.7-0.7-0.80.7-1.3-1.6-1.0-0.1
Time in open arm before self-admin0.30.31.10.40.60.30.71.0-0.10.50.50.5
Time in open arm after self-admin3.23.56.82.61.71.91.9-1.02.42.21.60.7
Sum of active levers in priming session hrs 5-60.30.31.40.2-0.4-0.2-0.3-1.20.40.1-0.5-0.7
Time to tail flick, vehicle, before self-admin0.30.30.70.80.30.20.40.40.30.90.70.3
Time to tail flick, vehicle, after self-admin0.30.31.00.80.40.40.4-0.00.51.00.3-0.1
Time to tail flick, test, before self-admin0.60.61.30.41.00.70.90.80.1-0.01.01.1
Time to tail flick, test, after self-admin0.70.71.11.00.90.80.90.30.90.91.00.7
Delta time to tail flick, vehicle, before/after SA0.90.81.51.10.91.20.9-0.81.20.90.60.4
Delta time to tail flick, test, before/after SA0.20.20.60.40.10.20.20.80.10.70.30.0
Ambulatory time before self-admin0.20.31.00.30.40.30.31.0-0.00.40.60.5
Ambulatory time after self-admin0.10.10.2-0.3-0.3-0.2-0.3-0.40.1-0.3-0.5-0.4
Total heroin consumption0.20.30.70.1-0.6-0.6-0.6-0.7-0.30.1-0.5-0.8
Area under the delay curve0.60.72.01.10.6-0.00.51.30.21.40.70.0
Delay disc. indifference point, 0s delay0.80.94.1-0.8-0.2-0.7-0.32.0-1.5-0.6-0.20.1
Delay disc. indifference point, 16s delay0.50.51.10.1-0.4-1.0-0.50.9-0.60.7-0.4-1.1
Delay disc. indifference point, 2s delay0.60.61.20.71.01.01.00.50.60.30.61.1
Delay disc. indifference point, 24s delay1.41.32.5-1.1-1.3-1.6-1.30.2-1.3-0.8-1.1-1.2
Delay disc. indifference point, 4s delay0.20.20.50.70.4-0.10.30.50.00.60.40.0
Delay disc. indifference point, 8s delay1.92.04.91.81.20.51.22.10.42.21.40.5
Delay discount exponential model param0.40.41.4-1.0-0.30.2-0.3-0.8-0.2-1.2-0.50.2
Delay discount hyperbolic model param0.50.51.3-1.1-0.5-0.1-0.5-0.9-0.2-1.1-0.6-0.1
Fecal boli incidents, locomotor time 11.11.22.3-0.9-1.2-1.5-1.30.0-1.1-0.6-1.2-1.5
Change in fecal boli incidents, locomotor task3.43.24.92.01.92.22.10.01.71.61.91.8
Time >=10cm from walls, locomotor time 10.10.10.2-0.1-0.20.1-0.2-0.40.50.1-0.1-0.2
Bouts of movement, locomotor time 13.64.06.3-1.8-2.5-2.5-2.5-0.3-1.7-1.3-2.0-2.4
Total resting periods, locomotor time 13.43.75.5-2.0-2.3-2.2-2.3-0.3-1.8-1.6-2.0-2.0
Rest time, locomotor task time 10.10.10.20.10.10.20.20.4-0.1-0.30.10.4
Distance moved, locomotor task time 10.30.31.0-0.8-0.4-0.4-0.30.6-1.0-0.6-0.5-0.3
Vertical activity count, locomotor time 10.20.20.60.20.20.50.30.20.60.70.50.4
Time >=10cm from walls, locomotor time 210.911.616.63.43.63.73.72.02.63.04.14.0
Bouts of movement, locomotor time 20.40.41.20.30.40.40.10.90.61.10.80.3
Total resting periods, locomotor time 20.30.30.90.20.30.2-0.00.80.61.00.70.2
Rest time, locomotor task time 24.35.07.3-2.3-2.4-2.3-2.3-1.4-1.7-2.6-2.7-2.2
Distance moved, locomotor task time 22.02.33.91.31.71.61.71.50.41.01.72.0
Vertical activity count, locomotor time 25.25.77.72.22.62.72.41.71.92.32.72.8
Weight adjusted by age0.70.81.70.51.10.81.11.3-0.10.20.81.3
Seeking ratio, delayed vs. immediate footshock1.11.32.51.01.11.61.2-0.61.50.60.91.2
Locomotion in novel chamber0.60.71.80.70.90.81.01.3-0.10.70.70.9
Locomotion in novel chamber post-restriction2.42.86.92.01.31.51.2-0.32.62.31.70.9
Progressive ratio0.10.10.4-0.1-0.3-0.5-0.7-0.40.30.20.3-0.4
Food seeking constrained by brief footshock0.00.00.0-0.20.0-0.10.00.1-0.2-0.20.20.2
Seeking ratio, punishment vs. effort0.20.20.5-0.5-0.1-0.00.20.6-0.7-0.7-0.50.2
Run reversals in cocaine runway, females0.80.84.50.80.00.3-0.0-2.11.20.6-0.0-0.5
Run reversals in cocaine runway, males1.61.62.1-1.4-1.3-1.4-1.2-0.9-1.1-1.3-1.4-1.3
Latency to leave start box in cocaine runway0.10.20.4-0.30.50.40.10.30.4-0.20.50.6
Latency to leave start box in cocaine runway, F0.10.10.2-0.4-0.2-0.5-0.50.4-0.2-0.2-0.0-0.2
Latency to leave start box in cocaine runway, M1.00.92.10.11.31.51.0-0.20.9-0.31.01.4
Cd content in liver0.20.30.80.60.40.30.40.40.50.90.60.2
Co content in liver0.30.30.8-0.1-0.7-0.8-0.6-0.4-0.50.1-0.7-0.9
Cu content in liver0.81.04.4-0.1-0.8-0.5-0.8-2.10.70.1-0.8-1.3
Fe content in liver0.91.14.0-2.0-0.6-0.2-0.6-0.1-0.6-2.0-0.9-0.3
K content in liver0.50.51.41.00.10.20.1-0.71.01.20.4-0.2
Mg content in liver1.51.53.71.80.70.80.6-1.21.81.90.6-0.2
Mn content in liver0.40.41.01.00.80.60.80.00.20.60.70.7
Na content in liver1.31.33.2-1.0-1.3-0.9-1.3-1.80.2-1.2-1.0-1.1
Rb content in liver3.54.49.03.02.21.92.1-0.02.12.91.91.2
Se content in liver0.20.20.30.60.50.50.5-0.50.50.40.10.1
Sr content in liver0.40.30.9-0.4-0.7-1.0-0.80.1-0.6-0.3-0.3-0.4
Zn content in liver0.50.62.3-0.2-0.8-0.5-0.8-1.50.7-0.2-0.4-0.7