Hectd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000006905 0.13 0.09 1.2e-11 0.11 0.1 0.1 0.11 2.2e-12 6.9e-11 9.6e-12 4.5e-12
2 Adipose isoform ratio ENSRNOT00000008459 0.02 0.02 9.3e-03 0.01 0.01 0.01 0 1.7e-02 5.9e-02 4.6e-02 8.8e-02
3 Adipose isoform ratio ENSRNOT00000108705 0.02 0.02 9.4e-03 0.01 0.01 0.01 0 1.5e-02 5.3e-02 5.4e-02 8.0e-02
4 BLA gene expression ENSRNOG00000006905 0.06 0.05 2.6e-03 -0 0.04 0 0 5.0e-01 3.9e-03 2.3e-01 1.7e-01
5 BLA intron excision ratio chr6:69206033:69209504 0.1 0.08 3.9e-04 0.05 0.06 0.03 0.06 8.9e-04 2.9e-04 6.9e-03 4.4e-04
6 BLA intron excision ratio chr6:69206174:69209504 0.1 0.08 4.2e-04 0.07 0.06 0.03 0.06 1.8e-04 3.7e-04 8.6e-03 5.5e-04
7 Brain gene expression ENSRNOG00000006905 0.05 0.04 5.2e-04 0.02 0.02 0 0.01 2.4e-03 1.1e-02 1.3e-01 1.8e-02
8 Brain mRNA stability ENSRNOG00000006905 0.05 0.04 2.1e-03 0 0.02 0.02 0.01 1.4e-01 4.8e-03 5.1e-03 2.1e-02
9 NAcc intron excision ratio chr6:69206033:69209504 0.04 0.03 7.2e-03 0.03 0.03 0.02 0.03 4.0e-03 2.7e-03 1.8e-02 5.4e-03
10 NAcc intron excision ratio chr6:69206174:69209504 0.04 0.03 4.6e-03 0.03 0.03 0.02 0.03 2.8e-03 1.6e-03 1.7e-02 5.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.41.42.1-1.40.2-0.2-1.51.2-1.2-1.2-1.41.3-1.3
BMI without tail0.91.94.3-2.11.9-1.9-1.20.4-0.3-1.8-1.30.7-0.7
Body weight1.35.317.0-1.34.1-4.10.6-1.92.4-1.80.4-1.51.4
Epididymis fat weight0.30.81.1-1.0-0.30.3-1.00.9-1.0-0.8-1.01.0-1.0
Glucose1.01.63.9-0.32.0-2.00.8-1.31.4-0.50.7-1.21.1
Heart weight0.91.32.20.11.3-1.31.0-1.41.50.61.0-1.31.3
Left kidney weight0.51.33.2-1.71.8-1.8-0.6-0.10.4-1.6-0.60.1-0.2
Right kidney weight0.51.54.0-2.01.7-1.7-0.90.20.2-1.7-1.00.4-0.5
Tail length0.72.05.5-0.02.3-2.30.7-1.41.7-0.70.6-1.21.1
Length with tail2.38.318.40.14.3-4.31.9-3.13.7-1.01.7-2.82.7
Length without tail1.63.56.80.52.6-2.61.4-2.12.5-0.81.2-1.91.8
Liver weight, left0.20.20.6-0.30.8-0.80.2-0.40.5-0.70.1-0.40.3
Liver weight, right0.20.31.4-0.40.8-0.8-0.30.00.2-1.2-0.40.1-0.1
Parametrial fat weight1.12.25.9-2.02.0-2.0-1.30.5-0.1-2.4-1.40.7-0.8
Retroperitoneal fat weight1.55.110.1-2.91.5-1.5-2.61.8-1.3-3.2-2.72.1-2.1
Intraocular pressure0.60.82.6-1.01.6-1.6-0.1-0.40.6-1.1-0.2-0.30.2
Extensor digitorum longus weight1.66.419.5-2.54.4-4.40.5-2.02.4-2.10.4-1.61.5
Soleus weight1.13.35.41.41.1-1.12.1-2.22.30.92.0-2.22.2
Tibialis anterior weight1.96.418.5-2.04.3-4.30.8-2.22.6-2.00.6-1.81.7
Tibia length1.64.56.41.91.2-1.22.4-2.52.51.52.4-2.52.5
Number of licking bursts0.10.10.2-0.2-0.20.2-0.30.3-0.40.1-0.20.3-0.3
Food consumed during 24 hour testing period1.01.21.70.80.8-0.81.1-1.31.30.81.1-1.21.2
Times rat made contact with spout0.91.01.4-1.0-0.20.2-1.21.1-1.1-0.9-1.21.1-1.1
Mean time between licks in bursts0.10.11.1-1.1-0.10.10.1-0.10.1-0.20.1-0.20.2
Mean num. licks in bursts0.10.10.6-0.50.5-0.5-0.30.10.0-0.7-0.30.1-0.2
Std. dev. time between licks in bursts0.40.40.8-0.6-0.40.4-0.70.7-0.9-0.4-0.70.8-0.8
Water consumed over 24 hours0.40.41.7-0.51.3-1.3-0.1-0.30.3-0.7-0.2-0.20.1
Indifference point 0 sec2.94.66.71.71.4-1.42.4-2.62.51.62.4-2.52.5
Indifference point AUC2.73.26.42.5-0.00.02.2-1.81.91.32.1-2.02.0
Indifference point function ln k0.40.51.7-1.30.4-0.4-0.90.6-0.6-0.6-0.80.7-0.7
Indifference point function log k0.40.51.7-1.30.4-0.4-0.90.6-0.6-0.6-0.80.7-0.7
Delay discounting total patch changes 0 sec3.25.27.31.91.4-1.42.6-2.72.61.82.5-2.72.7
Delay discounting total patch changes 12 sec3.74.96.62.31.1-1.12.5-2.62.61.62.5-2.52.5
Delay discounting total patch changes 18 sec0.91.22.51.60.6-0.61.2-1.21.20.81.2-1.21.2
Delay discounting total patch changes 24 sec1.41.82.61.60.4-0.41.5-1.51.51.41.5-1.41.4
Delay discounting total patch changes 6 sec2.94.56.41.81.4-1.42.4-2.52.51.22.3-2.52.5
Delay discounting time to switch 0 sec12.619.228.4-4.8-0.60.6-5.34.8-4.7-3.8-5.35.1-5.1
Delay discounting water rate 0 sec3.96.39.23.00.2-0.23.0-2.72.52.33.0-2.82.9
Delay discounting water rate 12 sec1.01.52.5-0.21.6-1.61.0-1.41.5-0.11.0-1.31.3
Delay discounting water rate 18 sec1.52.03.01.10.8-0.81.7-1.71.60.81.6-1.71.7
Delay discounting water rate 24 sec1.01.42.21.10.7-0.71.4-1.41.30.21.3-1.51.5
Delay discounting water rate 6 sec4.76.99.42.80.8-0.83.1-3.03.12.23.0-3.03.0
Locomotor activity5.58.713.60.53.7-3.72.6-3.53.70.12.5-3.33.2
Locomotor testing distance3.76.214.2-0.43.8-3.81.7-2.73.0-0.51.6-2.42.4
Locomotor testing rearing2.64.114.5-1.23.8-3.80.3-1.51.8-1.60.2-1.11.1
Light reinforcement 10.30.62.2-0.81.5-1.5-0.5-0.10.3-0.7-0.50.1-0.2
Light reinforcement 21.11.54.52.1-1.31.30.9-0.40.32.01.0-0.50.5
Reaction time number correct0.40.51.3-0.80.6-0.6-0.80.5-0.4-1.1-0.80.6-0.6
Reaction time mean minus median3.95.013.11.1-3.63.6-1.22.4-2.40.9-1.12.0-2.0
Reaction time mean minus median AUC2.83.69.40.9-3.13.1-1.12.0-2.00.8-0.91.7-1.7
Reaction time num false alarms0.30.50.90.4-0.10.10.8-0.80.50.90.9-0.80.8
Reaction time num false alarms AUC0.30.40.70.3-0.30.30.8-0.60.40.80.8-0.70.7
Reaction time trials correct on left0.40.51.3-0.80.6-0.6-0.80.5-0.4-1.1-0.80.6-0.6
Reaction time trials on left0.30.41.0-0.70.5-0.5-0.70.5-0.4-1.0-0.80.6-0.6
Reaction time mean1.42.03.2-0.7-1.41.4-1.41.7-1.8-0.5-1.31.6-1.6
Reaction time mean AUC1.72.33.6-0.9-1.41.4-1.61.8-1.9-0.6-1.51.8-1.8
Median of all reaction times1.11.42.0-1.4-0.50.5-1.41.3-1.4-1.0-1.31.4-1.4
Reaction time omissions2.02.89.61.1-3.13.1-0.11.1-1.31.80.00.8-0.7
Reaction time false alarm rate0.70.91.70.6-0.20.21.2-1.00.81.31.3-1.11.1
Reaction time premature initiation rate0.91.21.91.10.7-0.71.2-1.21.40.51.2-1.21.2
Reaction time premature initiations0.40.61.10.70.8-0.80.7-0.81.1-0.10.6-0.80.8
Std. dev. reaction times2.63.69.50.5-3.13.1-1.12.0-2.10.7-1.01.7-1.7
Reaction time trials completed0.30.41.0-0.70.5-0.5-0.70.5-0.4-1.0-0.80.6-0.6
Reaction time trials AUC0.30.51.3-0.80.7-0.7-0.70.4-0.4-1.1-0.80.5-0.5
Social response proportion0.30.30.60.10.2-0.20.7-0.60.80.20.6-0.70.7
Social responses0.70.91.40.70.6-0.61.1-1.11.20.51.0-1.11.1
Social time1.21.63.4-0.51.8-1.80.8-1.41.7-0.40.7-1.21.2
Conditioned locomotion0.60.71.91.0-1.41.40.40.1-0.31.10.5-0.10.1
Cocaine response after cond. corrected0.40.41.0-0.5-0.10.1-0.70.7-0.6-1.0-0.80.7-0.7
Cocaine response after cond. not corrected0.90.92.3-1.20.6-0.6-1.10.8-0.5-1.5-1.10.9-0.9
Cocaine response before conditioning0.40.51.1-1.11.0-1.0-0.70.2-0.1-0.7-0.70.5-0.5
Saline control response0.91.22.2-0.11.5-1.50.9-1.31.40.10.9-1.21.1
Condit. Reinf. active minus inactive responses0.00.00.10.2-0.30.3-0.10.2-0.2-0.2-0.10.2-0.2
Condit. Reinf. active-inactive response ratio0.10.10.50.4-0.70.70.00.2-0.30.20.00.2-0.1
Condit. Reinf. active responses0.00.10.10.3-0.40.4-0.10.2-0.2-0.0-0.10.2-0.2
Condit. Reinf. inactive responses0.10.10.4-0.60.4-0.4-0.40.2-0.1-0.4-0.40.3-0.3
Condit. Reinf. lever presses0.81.11.80.11.0-1.01.0-1.31.20.81.1-1.21.2
Condit. Reinf. lever reinforcers received0.40.50.80.80.2-0.20.9-0.80.80.40.9-0.80.8
Pavlov. Cond. lever latency1.82.44.0-0.4-1.11.1-1.82.0-1.8-0.9-1.81.9-1.9
Pavlov. Cond. magazine entry latency0.00.00.3-0.0-0.20.2-0.10.1-0.20.5-0.00.2-0.2
Pavlov. Cond. change in total contacts2.12.94.70.31.6-1.61.7-2.22.10.91.8-2.02.0
Pavlov. Cond. index score1.31.72.80.31.1-1.11.4-1.71.51.01.4-1.51.5
Pavlov. Cond. latency score1.31.72.70.60.9-0.91.4-1.61.51.11.5-1.51.5
Pavlov. Cond. lever contacts1.11.52.50.11.0-1.01.3-1.61.40.71.3-1.51.5
Pavlov. Cond. magazine entry number0.80.91.4-0.5-0.30.3-1.11.2-1.0-1.0-1.21.1-1.2
Pavlov. Cond. intertrial magazine entries0.20.20.7-0.1-0.80.8-0.30.6-0.5-0.0-0.30.4-0.4
Pavlov. Cond. lever-magazine prob. diff.1.41.82.90.31.1-1.11.4-1.71.51.11.4-1.61.5
Pavlov. Cond. response bias0.81.01.7-0.00.9-0.91.1-1.31.20.71.1-1.21.2
Conditioned reinforcement - actives2.72.63.81.70.1-0.12.0-1.81.91.51.9-1.91.9
Conditioned reinforcement - inactives0.91.01.90.00.9-0.91.0-1.21.40.20.9-1.21.2
Conditioned locomotion0.20.30.70.8-0.20.20.6-0.40.50.60.6-0.50.5
Intermittent access intake day 1-15 change0.60.61.4-1.11.2-1.2-0.1-0.40.8-1.0-0.2-0.20.2
Intermittent access intake escalation0.80.82.3-0.91.5-1.5-0.1-0.50.8-1.1-0.2-0.30.2
Intermittent access intake escalation 21.41.43.2-1.61.7-1.7-0.80.10.3-1.8-0.90.4-0.4
Intermitt. access day 1 inactive lever presses2.12.33.41.7-0.10.11.9-1.61.71.41.8-1.71.7
Intermitt. access day 15 inactive lever presses2.52.74.21.0-0.20.22.0-1.91.91.82.1-1.92.0
Intermitt. access escalation Index0.60.51.3-0.81.1-1.1-0.50.2-0.1-1.1-0.60.3-0.3
Intermittent access day 1 total infusions1.01.11.91.40.5-0.51.2-1.21.20.61.2-1.21.2
Intermittent access day 15 total infusions1.01.12.30.21.5-1.50.7-1.11.4-0.50.6-1.00.9
Intermittent access terminal intake (last 3 days)0.80.91.80.31.2-1.20.7-1.11.3-0.20.7-1.00.9
Intermittent access total infusions0.50.51.40.31.2-1.20.4-0.70.9-0.50.3-0.60.6
Intermittent access day 1 locomotion1.61.72.61.60.2-0.21.5-1.41.51.01.5-1.41.4
Intermittent access day 15 total locomotion0.60.61.7-0.31.3-1.30.4-0.70.8-0.60.3-0.60.6
Intermittent access total locomotion0.40.51.30.11.2-1.20.3-0.60.8-0.60.2-0.50.5
Intermittent access standard deviation0.60.61.80.00.7-0.70.7-0.91.3-0.20.6-0.80.8
Cocaine induced anxiety0.70.81.51.0-0.40.41.1-0.90.71.21.1-1.01.0
Post-drug Anxiety0.60.71.40.6-0.50.51.0-0.80.71.21.0-0.90.9
Baseline Anxiety1.21.31.8-1.2-0.60.6-1.31.4-1.3-0.7-1.31.3-1.3
Lifetime Intake0.40.41.10.21.0-1.00.3-0.60.8-0.40.3-0.50.5
Incentive Sensitization - Responses3.23.25.2-0.1-1.31.3-2.02.3-2.2-0.8-1.92.2-2.2
Incentive Sensitization - Breakpoint2.92.94.8-0.2-1.21.2-1.92.2-2.1-0.9-1.92.1-2.1
Progressive ratio test 1 active lever presses0.80.91.40.60.7-0.71.1-1.11.20.41.0-1.11.1
Progressive ratio test 1 breakpoint1.01.01.51.00.3-0.31.2-1.21.20.71.2-1.21.2
Progressive ratio test 1 inactive lever presses2.42.63.91.40.7-0.71.9-1.92.01.11.8-1.91.9
Progressive ratio test 2 active lever presses0.10.10.30.5-0.30.3-0.20.4-0.3-0.0-0.20.3-0.3
Progressive ratio test 2 breakpoint0.10.20.30.5-0.40.4-0.30.5-0.4-0.1-0.30.4-0.4
Progressive ratio test 2 inactive lever presses0.91.01.80.80.4-0.41.2-1.21.30.71.2-1.21.2
Total sessions with >9 infusions1.31.42.7-0.01.2-1.21.2-1.51.60.31.1-1.41.4
Short access day 1 total inactive lever presses3.33.79.0-0.43.0-3.01.2-2.02.3-0.81.1-1.81.7
Short access day 10 total inactive lever presses1.51.72.51.5-0.40.41.6-1.31.11.51.6-1.41.4
Short access day 1 total infusions1.51.63.5-0.21.9-1.90.9-1.41.6-0.40.8-1.21.2
Short access day 10 total infusions0.60.61.21.10.3-0.30.9-0.91.10.40.8-0.80.8
Short access total infusions0.20.20.70.20.9-0.90.2-0.40.5-0.40.1-0.30.3
Short access day 1 locomotion0.60.61.5-0.11.2-1.20.5-0.81.1-0.20.5-0.70.7
Short access day 10 total locomotion0.30.30.80.20.5-0.50.4-0.60.9-0.30.4-0.50.5
Short access total locomotion0.80.81.80.41.0-1.00.8-1.01.4-0.10.8-1.01.0
Compulsive drug intake0.40.41.20.4-0.40.40.7-0.40.11.10.8-0.60.6
One hour access (0.3 mA shock)1.72.03.80.21.8-1.81.1-1.62.0-0.41.0-1.51.4
One hour access (shock baseline)0.60.71.9-0.21.4-1.40.0-0.51.0-1.1-0.1-0.30.3
Number of responses in last shaping day0.20.20.60.8-0.30.30.5-0.50.70.40.5-0.40.4
Context. condit. distance diff. score0.81.02.9-1.60.3-0.3-1.00.9-0.7-1.7-1.10.8-0.8
Locomotion velocity, session 10.20.20.50.10.0-0.00.5-0.50.50.70.5-0.50.5
Locomotion distance, session 11.21.52.60.1-1.61.6-1.01.5-1.50.0-1.01.4-1.3
Locomotion velocity, session 21.21.44.21.4-2.02.00.40.3-0.51.60.50.1-0.1
Locomotion distance, session 21.42.05.11.0-2.32.3-0.71.3-1.51.1-0.51.2-1.1
Locomotion velocity, session 31.01.23.91.2-2.02.0-0.20.9-0.90.6-0.10.6-0.6
Locomotion distance, session 31.21.32.20.0-0.70.7-1.31.5-1.3-1.1-1.31.4-1.4
Stereotopy head waving bouts, day 30.91.03.70.9-1.91.90.30.4-0.61.10.40.1-0.1
Stereotopy head waving duration, day 30.81.02.51.2-1.61.60.7-0.1-0.11.50.7-0.30.3
Locomotion velocity, session 75.35.98.6-1.9-0.60.6-2.92.8-2.6-2.4-2.92.9-2.9
Locomotion distance, session 73.74.77.1-2.30.4-0.4-2.72.2-2.1-2.4-2.72.4-2.4
Stereotopy head waving bouts, day 70.70.81.20.9-0.30.31.1-0.90.81.01.1-1.01.0
Stereotopy head waving duration, day 70.81.02.01.4-1.11.11.1-0.60.51.41.1-0.80.8
Locomotion velocity, session 80.10.20.30.4-0.50.50.4-0.20.30.40.4-0.30.3
Locomotion distance, session 80.50.71.2-0.4-0.90.9-0.81.1-1.0-0.7-0.80.9-0.9
Degree of sensitization distance0.20.30.9-1.00.8-0.8-0.2-0.10.1-0.5-0.2-0.00.0
Degree of sensitization stereotypy0.80.81.30.50.5-0.51.1-1.11.10.51.0-1.11.1
Condit. Reinf. active minus inactive responses2.42.63.81.21.5-1.51.6-2.01.90.91.6-1.91.8
Condit. Reinf. active-inactive response ratio0.30.30.40.30.6-0.60.5-0.70.50.40.5-0.60.6
Condit. Reinf. active responses3.44.15.81.81.5-1.52.2-2.42.41.32.2-2.32.3
Condit. Reinf. inactive responses0.91.11.61.20.5-0.51.2-1.21.30.71.2-1.21.2
Incentive salience index mean3.44.15.52.21.3-1.32.2-2.32.31.42.2-2.32.3
Condit. Reinf. lever presses0.81.12.71.60.4-0.41.1-1.11.00.91.2-1.11.1
Time in familiar zone, hab. session 10.70.71.7-1.10.8-0.8-0.80.5-0.3-1.3-0.90.6-0.6
Time in novel zone, hab. session 10.60.61.10.6-0.30.31.0-0.80.61.01.0-0.90.9
Total zone transitions, hab. session 11.21.75.61.5-2.42.4-0.00.8-0.91.30.10.6-0.5
Total locomotion distance, hab. session 11.92.75.20.1-2.32.3-1.31.9-2.00.2-1.21.8-1.7
Locomotion velocity, hab. session 11.62.36.31.1-2.52.5-0.71.5-1.61.0-0.61.3-1.2
Time in familiar zone, hab. session 21.71.83.8-2.00.5-0.5-1.61.2-1.1-1.6-1.61.3-1.4
Time in novel zone, hab. session 23.03.04.21.90.2-0.22.0-1.91.81.82.1-2.02.0
Total zone transitions, hab. session 22.32.98.62.1-2.92.90.50.5-0.82.40.60.3-0.2
Total locomotion distance, hab. session 21.62.26.51.7-2.52.50.20.6-0.92.00.40.4-0.4
Locomotion velocity, hab. session 22.02.78.22.0-2.92.90.20.7-1.02.10.40.5-0.4
Novel to familiar place preference ratio0.91.01.71.30.0-0.01.2-1.01.00.81.2-1.11.1
Novelty place preference2.22.33.31.70.3-0.31.8-1.71.71.21.8-1.81.8
Time in novel zone, NPP test1.91.92.71.40.5-0.51.6-1.61.61.01.6-1.71.7
Total zone transitions, NPP test0.71.12.91.4-1.71.70.20.4-0.61.50.30.3-0.2
Total locomotion distance, NPP test1.01.44.01.4-2.02.00.10.6-0.81.50.20.4-0.4
Locomotion velocity, NPP test0.81.13.31.2-1.81.8-0.10.7-0.81.30.00.5-0.5
Pavlov. Cond. lever latency0.70.93.3-1.80.4-0.4-0.90.7-0.5-1.2-1.00.7-0.7
Pavlov. Cond. magazine entry latency1.01.22.41.0-1.51.5-0.71.1-1.40.6-0.61.1-1.1
Pavlov. Cond. change in total contacts0.60.61.91.1-0.70.70.6-0.40.11.40.8-0.40.4
Pavlov. Cond. index score0.60.82.51.6-1.31.30.10.3-0.71.10.20.3-0.3
Pavlov. Cond. latency score0.60.82.81.7-1.21.20.20.2-0.51.30.40.1-0.1
Pavlov. Cond. lever contacts0.20.21.21.1-0.10.10.3-0.30.20.70.4-0.20.2
Pavlov. Cond. magazine entry number1.01.33.2-1.31.8-1.80.4-0.91.2-1.10.2-0.80.8
Pavlov. Cond. intertrial magazine entries0.70.82.2-1.51.4-1.4-0.4-0.20.4-1.2-0.50.0-0.0
Pavlov. Cond. lever-magazine prob. diff.0.60.71.81.3-1.31.3-0.10.5-0.80.90.10.4-0.4
Pavlov. Cond. response bias0.60.71.71.3-1.31.3-0.10.5-0.80.90.10.4-0.4
Bone: apparent density1.11.74.7-1.02.2-2.20.5-1.21.5-1.10.4-1.01.0
Bone surface1.73.04.70.91.4-1.41.9-2.12.20.71.8-2.12.1
Bone volume1.62.74.70.11.9-1.91.6-2.02.20.11.4-1.91.9
Bone: connectivity density2.03.19.0-1.13.0-3.00.6-1.51.8-1.60.4-1.31.2
Bone: cortical apparent density1.52.03.2-1.80.0-0.0-1.71.4-1.4-1.4-1.71.6-1.6
Bone: cortical area3.04.66.72.01.3-1.32.4-2.52.60.92.3-2.62.6
Bone: cortical porosity1.11.22.61.6-0.30.31.3-1.01.10.81.3-1.21.2
Bone: cortical porosity1.51.63.92.0-0.30.31.5-1.21.21.01.5-1.31.3
Bone: cortical thickness0.30.40.80.40.9-0.90.5-0.70.8-0.50.4-0.70.7
Bone: cortical thickness0.10.10.50.1-0.20.2-0.20.2-0.1-0.7-0.20.2-0.2
Bone: cortical tissue density1.62.03.3-1.8-0.10.1-1.71.5-1.4-1.3-1.71.6-1.6
Bone: elastic displacement1.11.23.0-1.70.8-0.8-1.20.7-0.5-1.6-1.20.9-0.9
Bone: elastic work1.31.74.4-1.51.7-1.7-1.20.5-0.1-2.1-1.20.7-0.7
Bone: endosteal estimation2.55.38.32.7-0.60.62.8-2.21.92.92.8-2.52.5
Bone: endosteal perimeter3.98.111.93.5-0.20.23.4-2.92.83.03.4-3.13.2
Bone: final force0.00.10.50.2-0.00.00.10.00.1-0.7-0.0-0.10.1
Bone: final moment0.00.10.30.3-0.10.10.3-0.10.2-0.60.1-0.20.2
Bone: marrow area2.55.58.32.8-0.60.62.9-2.22.02.92.8-2.52.6
Bone: maximum diameter5.910.715.73.80.3-0.34.0-3.53.33.23.9-3.73.8
Bone: maximum force0.30.51.11.00.0-0.01.0-0.70.80.00.8-0.90.9
Bone: maximum moment0.40.61.21.1-0.10.11.0-0.80.90.10.9-1.01.0
Bone: minimum diameter1.93.65.22.10.6-0.62.3-2.12.21.22.2-2.32.3
Bone: periosteal estimation3.97.912.03.30.0-0.03.5-2.92.82.73.4-3.23.3
Bone: periosteal perimeter3.35.48.12.80.3-0.32.8-2.52.51.92.7-2.72.7
Bone: post-yield work0.81.11.81.2-0.30.31.4-1.01.10.91.3-1.21.2
Bone: stiffness0.60.92.91.7-1.11.11.0-0.30.20.80.9-0.60.6
Bone: tissue strength0.60.50.7-0.8-0.30.3-0.80.8-0.8-0.6-0.80.8-0.8
Bone: trabecular number1.32.05.9-1.52.4-2.4-0.0-0.81.2-1.8-0.2-0.50.5
Bone: trabecular spacing3.54.57.4-0.6-2.22.2-2.12.6-2.7-0.5-2.02.5-2.5
Bone: trabecular thickness0.91.12.4-0.61.5-1.50.7-1.11.3-0.40.6-1.01.0
Bone: trabecular tissue density1.01.44.51.3-2.12.10.10.6-0.71.40.20.4-0.4
Breakpoint value in progressive ratio session2.02.23.5-0.11.9-1.91.3-1.81.70.21.3-1.71.7
Distance traveled before self-admin0.10.11.01.0-0.20.20.2-0.20.20.20.2-0.20.2
Distance traveled after self-admin0.20.20.3-0.3-0.50.5-0.50.5-0.50.0-0.40.5-0.5
Delta time in closed arm before/after self-admin0.50.51.10.60.5-0.50.8-0.91.10.20.7-0.80.8
Delta time in open arm before/after self-admin0.10.10.8-0.90.4-0.4-0.1-0.1-0.1-0.4-0.1-0.00.0
Diff in mean of infusions in LGA sessions0.40.51.60.4-1.31.30.00.3-0.70.80.10.3-0.2
Extinction: sum of active levers before priming1.92.07.2-0.52.7-2.70.0-0.91.1-1.6-0.1-0.60.6
Active lever presses in extinction session 62.52.47.5-0.62.7-2.70.6-1.41.6-0.90.5-1.21.1
Delta distance traveled before/after self-admin0.30.30.6-0.6-0.80.8-0.40.6-0.60.4-0.40.5-0.5
Delta ambulatory time before/after self-admin0.50.50.9-0.7-0.90.9-0.50.7-0.80.4-0.50.7-0.7
Time in closed arm before self-admin1.51.73.50.3-1.21.2-1.31.6-1.9-0.3-1.21.5-1.5
Time in closed arm after self-admin0.60.61.40.8-1.21.2-0.50.8-0.90.3-0.40.7-0.7
Time in open arm before self-admin0.70.71.31.1-0.30.31.0-0.80.81.11.0-0.80.8
Time in open arm after self-admin0.30.40.90.6-0.90.90.5-0.20.11.00.5-0.30.3
Sum of active levers in priming session hrs 5-60.70.71.6-0.41.3-1.30.5-0.91.1-0.20.4-0.80.7
Time to tail flick, vehicle, before self-admin0.10.10.40.5-0.60.60.3-0.10.00.40.4-0.20.2
Time to tail flick, vehicle, after self-admin0.70.81.61.3-0.50.51.0-0.70.61.21.0-0.80.8
Time to tail flick, test, before self-admin0.20.20.4-0.40.5-0.5-0.40.2-0.0-0.6-0.40.3-0.3
Time to tail flick, test, after self-admin1.01.01.9-1.21.4-1.40.6-1.01.2-0.20.5-0.90.9
Delta time to tail flick, vehicle, before/after SA0.30.30.70.5-0.20.20.7-0.50.50.80.7-0.60.6
Delta time to tail flick, test, before/after SA0.10.10.5-0.7-0.20.20.2-0.10.10.30.2-0.20.2
Ambulatory time before self-admin0.10.10.70.80.0-0.00.1-0.10.10.00.1-0.10.1
Ambulatory time after self-admin0.50.50.7-0.7-0.40.4-0.90.8-0.8-0.4-0.80.9-0.9
Total heroin consumption1.31.52.5-0.31.6-1.61.1-1.51.40.11.0-1.41.4
Area under the delay curve2.42.63.81.9-0.20.22.0-1.71.71.41.9-1.81.8
Delay disc. indifference point, 0s delay0.91.01.60.40.2-0.21.2-1.21.20.61.2-1.31.3
Delay disc. indifference point, 16s delay1.91.93.41.8-0.50.51.7-1.31.21.61.7-1.41.4
Delay disc. indifference point, 2s delay0.70.81.30.70.4-0.41.0-1.01.10.41.0-1.11.1
Delay disc. indifference point, 24s delay4.34.26.12.10.1-0.12.4-2.32.32.12.5-2.32.3
Delay disc. indifference point, 4s delay0.30.30.90.9-1.01.00.30.1-0.00.20.2-0.00.0
Delay disc. indifference point, 8s delay0.60.71.10.90.3-0.30.9-0.91.00.40.9-0.90.9
Delay discount exponential model param1.92.03.4-1.80.3-0.3-1.71.4-1.4-1.3-1.71.5-1.5
Delay discount hyperbolic model param1.71.83.0-1.70.3-0.3-1.61.3-1.4-1.2-1.61.5-1.5
Fecal boli incidents, locomotor time 11.21.34.3-1.32.1-2.1-0.0-0.70.9-1.0-0.1-0.40.4
Change in fecal boli incidents, locomotor task0.10.10.5-0.40.2-0.2-0.30.2-0.3-0.7-0.30.2-0.2
Time >=10cm from walls, locomotor time 10.50.50.90.60.5-0.50.8-0.91.00.00.8-0.90.9
Bouts of movement, locomotor time 11.82.03.11.00.2-0.21.8-1.71.61.31.8-1.71.7
Total resting periods, locomotor time 12.12.33.51.10.1-0.11.9-1.81.71.51.9-1.81.8
Rest time, locomotor task time 13.53.96.21.5-0.30.32.4-2.11.92.52.5-2.22.2
Distance moved, locomotor task time 11.41.52.9-1.20.4-0.4-1.41.2-1.2-1.7-1.51.3-1.3
Vertical activity count, locomotor time 11.41.42.7-1.40.7-0.7-1.41.0-1.0-1.6-1.41.1-1.2
Time >=10cm from walls, locomotor time 20.90.91.80.51.4-1.40.7-1.01.3-0.50.6-0.90.9
Bouts of movement, locomotor time 20.40.41.01.0-0.30.30.7-0.50.40.80.7-0.60.6
Total resting periods, locomotor time 20.20.20.60.8-0.50.50.4-0.20.10.70.4-0.30.3
Rest time, locomotor task time 20.00.00.1-0.20.0-0.00.1-0.10.10.10.1-0.10.1
Distance moved, locomotor task time 20.10.10.20.40.2-0.20.5-0.50.30.20.4-0.50.5
Vertical activity count, locomotor time 20.10.10.20.1-0.40.4-0.10.2-0.30.4-0.10.1-0.1
Weight adjusted by age0.40.40.8-0.4-0.30.3-0.80.8-0.9-0.3-0.70.8-0.8
Seeking ratio, delayed vs. immediate footshock0.60.71.71.3-1.21.2-0.30.8-0.90.2-0.30.6-0.6
Locomotion in novel chamber2.12.64.1-0.6-1.21.2-1.72.0-1.9-1.2-1.71.9-1.9
Locomotion in novel chamber post-restriction1.01.12.81.7-1.51.50.7-0.20.01.70.8-0.30.4
Progressive ratio0.70.82.90.0-1.71.70.10.5-0.61.10.10.3-0.2
Food seeking constrained by brief footshock0.20.20.50.4-0.70.70.5-0.20.10.60.5-0.30.4
Seeking ratio, punishment vs. effort0.20.31.0-0.01.0-1.00.1-0.40.5-0.50.1-0.30.3
Run reversals in cocaine runway, females0.80.82.30.6-1.51.50.50.0-0.21.50.6-0.10.2
Run reversals in cocaine runway, males0.10.10.40.40.2-0.2-0.20.2-0.2-0.7-0.30.2-0.2
Latency to leave start box in cocaine runway0.20.20.3-0.4-0.40.4-0.50.5-0.60.2-0.40.5-0.5
Latency to leave start box in cocaine runway, F0.30.30.6-0.5-0.70.7-0.50.6-0.80.1-0.50.6-0.6
Latency to leave start box in cocaine runway, M0.00.00.20.10.0-0.00.1-0.10.10.40.1-0.10.1
Cd content in liver0.60.72.0-0.81.4-1.4-0.3-0.20.3-1.4-0.4-0.10.0
Co content in liver0.40.41.1-0.71.1-1.1-0.2-0.20.3-1.0-0.2-0.10.1
Cu content in liver0.70.81.2-0.6-0.30.3-1.01.1-1.0-1.0-1.01.1-1.1
Fe content in liver0.50.61.0-1.0-0.30.3-0.90.8-0.8-0.4-0.80.9-0.9
K content in liver3.83.811.31.8-3.43.4-0.61.8-1.81.1-0.51.4-1.3
Mg content in liver4.44.510.30.6-3.23.2-1.42.4-2.40.4-1.32.1-2.1
Mn content in liver2.93.38.02.8-2.72.71.4-0.30.12.51.4-0.60.7
Na content in liver1.92.03.1-0.3-1.31.3-1.51.8-1.8-0.5-1.41.7-1.7
Rb content in liver1.92.46.20.4-2.52.5-0.91.7-1.70.5-0.81.4-1.4
Se content in liver3.94.77.8-0.2-2.42.4-2.12.6-2.8-0.1-1.92.5-2.5
Sr content in liver0.30.30.7-0.80.8-0.8-0.40.10.0-0.8-0.40.2-0.2
Zn content in liver0.20.31.51.2-0.50.5-0.20.4-0.3-0.1-0.20.4-0.4