Ankrd24

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000006759 0.09 0.06 5.2e-07 0.03 0.05 0.05 0.05 3.3e-04 2.6e-06 3.9e-06 4.3e-06
2 Adipose mRNA stability ENSRNOG00000006759 0.09 0.07 5.1e-07 0.06 0.05 0.05 0.05 8.7e-07 1.6e-06 2.4e-06 1.5e-06
3 BLA gene expression ENSRNOG00000006759 0.21 0.13 1.1e-08 0.13 0.15 0.15 0.15 2.5e-07 1.7e-08 2.3e-08 1.6e-08
4 BLA mRNA stability ENSRNOG00000006759 0.09 0.07 1.2e-03 0.04 0.05 0.06 0.04 3.1e-03 7.3e-04 6.2e-04 4.3e-03
5 Brain gene expression ENSRNOG00000006759 0.28 0.15 0.0e+00 0.11 0.19 0.2 0.2 4.7e-10 1.4e-17 2.2e-18 3.5e-18
6 Brain mRNA stability ENSRNOG00000006759 0.07 0.05 6.9e-05 0.04 0.04 0.04 0.04 1.1e-04 3.1e-04 3.4e-04 2.9e-04
7 LHb gene expression ENSRNOG00000006759 0.22 0.14 2.5e-03 0.03 0.03 0.04 0.04 5.4e-02 6.8e-02 3.8e-02 4.7e-02
8 Liver gene expression ENSRNOG00000006759 0.04 0.03 1.5e-03 0.01 0.02 0.02 0.02 8.7e-03 1.2e-03 2.0e-03 1.7e-03
9 Liver intron excision ratio chr7:8063190:8065278 0.03 0.02 5.4e-03 0.01 0.01 0 0.01 9.6e-03 2.6e-02 1.5e-01 4.2e-02
10 Liver mRNA stability ENSRNOG00000006759 0.02 0.02 2.9e-03 0.01 0.01 0.01 0.01 3.2e-02 1.5e-02 1.9e-02 2.5e-02
11 NAcc gene expression ENSRNOG00000006759 0.15 0.1 3.6e-09 0.11 0.11 0.11 0.1 1.5e-08 1.2e-08 1.6e-08 4.8e-08
12 OFC gene expression ENSRNOG00000006759 0.25 0.15 1.6e-04 0.2 0.16 0.14 0.18 2.0e-05 1.2e-04 2.7e-04 4.1e-05
13 PL gene expression ENSRNOG00000006759 0.32 0.16 0.0e+00 0.22 0.27 0.25 0.25 5.8e-17 2.3e-20 2.5e-19 2.5e-19
14 PL mRNA stability ENSRNOG00000006759 0.05 0.04 8.7e-03 -0 0.01 0.01 0 3.6e-01 3.4e-02 4.9e-02 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail4.314.122.5-2.84.6-4.03.3-3.34.6-1.0-3.14.64.7-3.7-4.7-3.52.9
BMI without tail1.94.06.9-2.02.0-2.31.1-2.12.0-1.1-2.02.42.3-2.2-2.6-2.20.8
Body weight0.93.65.8-1.52.2-2.21.5-1.82.2-0.7-1.72.42.4-1.9-2.2-1.91.3
Epididymis fat weight0.10.31.0-0.4-0.8-0.0-0.9-0.2-0.8-0.6-0.3-0.3-0.5-0.10.1-0.2-1.0
Glucose0.81.21.9-0.91.2-1.20.8-1.11.3-0.4-1.01.31.3-1.1-1.4-1.10.7
Heart weight0.20.41.2-0.3-0.90.1-0.9-0.1-0.9-0.6-0.2-0.4-0.7-0.00.2-0.1-1.1
Left kidney weight0.30.81.61.2-0.01.10.41.2-0.01.31.2-0.8-0.41.10.61.10.7
Right kidney weight1.13.14.91.5-1.92.0-1.31.8-1.90.81.7-2.2-2.21.92.01.9-1.0
Tail length1.85.311.01.0-3.32.0-2.81.4-3.3-0.31.2-2.6-3.11.72.71.6-2.7
Length with tail1.34.68.31.6-2.62.2-1.81.9-2.60.51.7-2.6-2.72.12.92.0-1.6
Length without tail0.30.71.41.2-0.00.90.41.0-0.01.11.1-0.7-0.31.01.01.00.7
Liver weight, left2.03.25.5-1.71.9-2.01.2-1.81.8-0.9-1.72.22.1-2.0-2.3-1.90.9
Liver weight, right1.01.73.0-0.81.7-1.31.3-1.01.7-0.1-0.91.61.7-1.2-1.6-1.11.3
Parametrial fat weight0.20.51.20.1-1.00.4-0.80.2-1.1-0.40.2-0.7-0.90.30.90.3-1.0
Retroperitoneal fat weight0.51.82.8-1.41.1-1.70.6-1.61.1-1.1-1.51.71.4-1.6-1.2-1.60.2
Intraocular pressure0.60.92.1-1.3-0.6-0.6-0.8-1.1-0.5-1.5-1.10.2-0.1-0.9-0.7-1.0-1.3
Extensor digitorum longus weight3.815.222.4-3.73.9-4.52.6-4.13.9-2.2-3.94.74.5-4.3-4.7-4.21.6
Soleus weight5.917.228.4-2.95.2-4.34.0-3.55.2-1.0-3.35.05.3-3.9-5.0-3.83.4
Tibialis anterior weight0.62.03.3-0.91.8-1.41.4-1.21.8-0.2-1.01.71.8-1.3-1.8-1.21.2
Tibia length0.51.43.10.5-1.71.0-1.40.8-1.8-0.20.6-1.3-1.60.91.40.8-1.4
Number of licking bursts0.80.91.9-1.30.0-1.1-0.3-1.2-0.0-1.4-1.30.80.4-1.2-0.6-1.2-0.9
Food consumed during 24 hour testing period0.30.40.6-0.50.8-0.70.6-0.60.8-0.2-0.50.80.8-0.6-0.8-0.60.5
Times rat made contact with spout0.50.50.9-1.00.2-0.9-0.0-1.00.3-0.9-0.90.70.5-0.9-0.8-0.9-0.4
Mean time between licks in bursts2.23.06.40.7-2.51.5-2.01.0-2.5-0.40.8-2.0-2.41.22.11.2-2.1
Mean num. licks in bursts0.10.10.30.40.10.40.10.40.20.50.4-0.2-0.00.40.00.40.4
Std. dev. time between licks in bursts1.31.52.31.5-0.71.5-0.21.5-0.71.31.5-1.3-1.01.51.41.50.2
Water consumed over 24 hours0.50.61.90.61.00.11.10.41.01.00.50.30.70.3-0.30.31.4
Indifference point 0 sec0.10.10.4-0.10.5-0.30.5-0.20.60.1-0.20.40.5-0.2-0.2-0.20.5
Indifference point AUC0.60.71.40.4-1.20.9-0.90.7-1.20.10.6-1.1-1.20.70.80.7-0.9
Indifference point function ln k0.20.30.5-0.40.6-0.70.4-0.60.6-0.3-0.50.70.7-0.6-0.5-0.60.3
Indifference point function log k0.20.30.5-0.40.6-0.70.4-0.60.6-0.3-0.50.70.7-0.6-0.5-0.60.3
Delay discounting total patch changes 0 sec0.10.10.3-0.20.4-0.40.3-0.30.5-0.1-0.30.50.5-0.3-0.3-0.30.3
Delay discounting total patch changes 12 sec0.50.71.2-1.10.3-1.0-0.0-1.10.5-0.9-1.10.80.6-1.0-1.1-1.0-0.3
Delay discounting total patch changes 18 sec0.60.81.30.5-1.10.9-0.90.7-1.20.10.6-1.0-1.10.81.10.7-0.8
Delay discounting total patch changes 24 sec0.10.10.20.4-0.30.5-0.30.4-0.20.30.4-0.5-0.40.40.30.4-0.1
Delay discounting total patch changes 6 sec0.10.10.40.2-0.50.3-0.30.2-0.4-0.10.2-0.5-0.40.30.70.3-0.3
Delay discounting time to switch 0 sec0.91.33.80.21.8-0.51.6-0.11.90.90.11.01.5-0.3-0.9-0.22.0
Delay discounting water rate 0 sec0.50.82.1-1.2-0.7-0.7-0.8-1.1-0.5-1.4-1.20.3-0.1-1.0-0.4-1.0-1.3
Delay discounting water rate 12 sec1.82.64.1-2.00.9-2.00.2-2.00.8-1.7-2.01.81.3-2.0-1.8-2.0-0.4
Delay discounting water rate 18 sec2.02.76.4-2.2-1.0-1.4-1.5-1.9-0.8-2.5-2.00.7-0.1-1.7-0.9-1.8-2.2
Delay discounting water rate 24 sec3.54.89.9-3.0-0.2-2.4-1.0-2.8-0.1-3.1-2.91.80.8-2.6-1.6-2.7-2.0
Delay discounting water rate 6 sec0.91.33.9-1.3-1.1-0.7-1.6-1.0-1.1-1.8-1.20.1-0.6-0.80.0-0.9-2.0
Locomotor activity3.25.18.82.4-1.92.6-1.12.5-2.01.52.4-2.6-2.42.63.02.6-0.6
Locomotor testing distance1.72.95.01.7-1.61.9-0.91.8-1.71.01.7-2.0-1.91.92.21.9-0.6
Locomotor testing rearing0.00.00.1-0.2-0.2-0.1-0.2-0.2-0.3-0.3-0.20.0-0.1-0.1-0.0-0.2-0.4
Light reinforcement 13.86.911.42.0-3.22.8-2.32.3-3.10.72.2-3.2-3.42.63.42.5-2.0
Light reinforcement 21.11.52.80.9-1.51.2-1.01.0-1.50.31.0-1.4-1.51.21.71.2-0.9
Reaction time number correct1.11.62.7-1.60.6-1.5-0.0-1.60.6-1.4-1.61.40.9-1.6-1.4-1.6-0.4
Reaction time mean minus median0.70.91.70.8-1.11.2-0.51.0-1.00.50.9-1.3-1.11.01.11.0-0.5
Reaction time mean minus median AUC1.11.43.01.60.21.30.91.50.11.71.5-0.9-0.21.30.81.41.2
Reaction time num false alarms0.10.10.3-0.50.1-0.5-0.1-0.40.1-0.4-0.50.40.2-0.4-0.4-0.4-0.2
Reaction time num false alarms AUC0.30.50.9-0.90.2-0.8-0.2-0.80.1-0.8-0.90.70.3-0.8-0.8-0.8-0.5
Reaction time trials correct on left1.11.62.7-1.60.6-1.5-0.0-1.60.6-1.4-1.61.40.9-1.6-1.4-1.6-0.4
Reaction time trials on left1.11.52.4-1.60.6-1.50.0-1.50.6-1.3-1.51.31.0-1.5-1.4-1.5-0.4
Reaction time mean0.50.71.71.10.20.90.71.00.31.31.1-0.6-0.00.90.50.91.0
Reaction time mean AUC0.50.61.51.00.30.80.80.90.41.21.0-0.50.10.80.40.81.1
Median of all reaction times0.40.61.90.80.80.41.10.60.81.20.7-0.00.50.5-0.00.51.4
Reaction time omissions0.30.30.60.7-0.40.7-0.10.7-0.50.50.7-0.7-0.60.70.80.7-0.0
Reaction time false alarm rate0.00.00.00.10.10.10.10.10.10.20.1-0.00.00.1-0.10.10.2
Reaction time premature initiation rate0.60.82.4-0.3-1.30.2-1.4-0.2-1.3-0.9-0.3-0.6-1.00.00.8-0.0-1.6
Reaction time premature initiations0.91.23.7-1.2-1.1-0.6-1.5-1.0-1.1-1.8-1.10.1-0.6-0.80.1-0.9-1.9
Std. dev. reaction times0.60.81.41.0-0.51.20.21.1-0.51.01.1-1.1-0.61.00.81.00.3
Reaction time trials completed1.11.52.4-1.60.6-1.50.0-1.50.6-1.3-1.51.31.0-1.5-1.4-1.5-0.4
Reaction time trials AUC1.31.83.1-1.80.5-1.6-0.1-1.70.5-1.5-1.71.40.9-1.7-1.4-1.7-0.6
Social response proportion0.70.71.10.9-0.71.0-0.41.0-0.70.71.0-1.0-0.91.00.91.0-0.1
Social responses6.48.312.42.7-2.83.3-1.93.1-3.01.72.9-3.5-3.43.23.43.2-1.2
Social time0.70.91.5-0.91.0-1.10.6-1.00.9-0.6-1.01.21.1-1.0-1.0-1.00.4
Conditioned locomotion2.63.04.6-2.11.1-2.10.3-2.11.1-1.7-2.12.01.5-2.1-2.0-2.1-0.2
Cocaine response after cond. corrected5.46.08.7-2.62.1-2.91.1-2.82.1-1.9-2.72.92.6-2.9-2.9-2.90.4
Cocaine response after cond. not corrected6.06.69.6-2.82.1-3.11.1-3.02.1-2.0-2.93.12.7-3.0-3.0-3.00.4
Cocaine response before conditioning0.50.60.90.8-0.70.9-0.40.9-0.70.60.9-0.9-0.80.90.90.9-0.1
Saline control response0.10.20.3-0.50.1-0.5-0.1-0.50.2-0.5-0.50.40.3-0.5-0.4-0.5-0.2
Condit. Reinf. active minus inactive responses1.31.63.80.0-1.90.8-1.70.3-1.9-0.70.2-1.2-1.70.51.20.5-1.9
Condit. Reinf. active-inactive response ratio1.01.02.5-1.3-0.7-0.8-1.0-1.1-0.7-1.6-1.20.4-0.2-1.0-0.4-1.0-1.5
Condit. Reinf. active responses1.52.03.60.8-1.91.4-1.51.1-1.80.11.0-1.7-1.91.31.71.2-1.4
Condit. Reinf. inactive responses1.31.72.41.4-1.11.5-0.61.4-1.00.91.4-1.6-1.41.51.51.5-0.3
Condit. Reinf. lever presses1.31.84.00.3-2.01.0-1.80.6-2.0-0.50.5-1.4-1.80.81.40.7-1.8
Condit. Reinf. lever reinforcers received1.01.53.20.5-1.81.1-1.50.7-1.7-0.20.6-1.4-1.70.91.30.8-1.5
Pavlov. Cond. lever latency0.70.91.4-0.81.1-1.10.8-0.91.1-0.4-0.91.21.2-1.0-1.1-1.00.6
Pavlov. Cond. magazine entry latency0.50.61.00.8-0.60.9-0.30.9-0.80.60.9-0.9-0.80.91.00.9-0.1
Pavlov. Cond. change in total contacts0.60.81.50.5-1.20.9-1.00.7-1.20.00.6-1.1-1.20.81.00.8-0.9
Pavlov. Cond. index score0.70.91.40.7-1.11.0-0.90.8-1.20.30.8-1.1-1.20.91.10.9-0.7
Pavlov. Cond. latency score0.70.91.40.9-1.01.1-0.71.0-1.10.50.9-1.1-1.11.11.21.0-0.5
Pavlov. Cond. lever contacts0.50.71.40.4-1.20.7-1.00.5-1.2-0.10.5-1.0-1.10.60.90.6-0.9
Pavlov. Cond. magazine entry number0.91.11.6-1.10.9-1.20.6-1.11.0-0.7-1.11.21.1-1.2-1.3-1.20.3
Pavlov. Cond. intertrial magazine entries0.70.91.4-1.10.6-1.20.2-1.20.7-0.9-1.21.10.8-1.2-0.9-1.2-0.1
Pavlov. Cond. lever-magazine prob. diff.0.81.01.50.9-1.11.1-0.81.0-1.20.40.9-1.2-1.21.11.21.0-0.6
Pavlov. Cond. response bias1.21.63.20.6-1.71.2-1.50.8-1.8-0.10.8-1.5-1.71.01.41.0-1.4
Conditioned reinforcement - actives2.02.03.01.1-1.61.6-1.11.3-1.70.61.2-1.7-1.71.41.61.4-0.9
Conditioned reinforcement - inactives1.31.42.4-1.40.6-1.50.1-1.50.6-1.3-1.51.41.0-1.5-1.0-1.5-0.3
Conditioned locomotion5.26.310.61.6-3.22.6-2.42.0-3.20.41.9-3.0-3.32.33.02.2-2.2
Intermittent access intake day 1-15 change3.93.98.10.9-2.81.7-2.31.2-2.8-0.21.0-2.2-2.61.52.51.4-2.2
Intermittent access intake escalation3.53.58.7-0.0-2.90.9-2.70.4-3.0-1.20.2-1.7-2.40.72.00.6-2.9
Intermittent access intake escalation 24.34.310.20.2-3.21.3-2.90.7-3.2-1.00.4-2.1-2.81.02.20.9-3.1
Intermitt. access day 1 inactive lever presses0.40.41.4-0.5-0.9-0.1-1.0-0.3-0.9-0.8-0.4-0.3-0.6-0.20.3-0.2-1.2
Intermitt. access day 15 inactive lever presses0.20.30.8-0.2-0.7-0.0-0.7-0.1-0.8-0.6-0.2-0.2-0.5-0.10.5-0.1-0.9
Intermitt. access escalation Index0.90.81.91.00.80.61.10.90.71.41.0-0.20.30.80.10.81.4
Intermittent access day 1 total infusions0.10.10.2-0.00.4-0.20.4-0.00.20.1-0.10.30.4-0.1-0.1-0.10.4
Intermittent access day 15 total infusions0.91.02.90.0-1.50.5-1.40.3-1.7-0.60.1-0.9-1.30.41.20.3-1.5
Intermittent access terminal intake (last 3 days)0.60.71.60.5-1.00.8-0.80.7-1.30.10.6-1.0-1.10.71.00.7-0.8
Intermittent access total infusions0.10.10.4-0.2-0.4-0.1-0.4-0.1-0.6-0.4-0.2-0.1-0.3-0.10.4-0.1-0.5
Intermittent access day 1 locomotion0.10.10.5-0.1-0.50.0-0.50.0-0.7-0.4-0.1-0.2-0.40.00.5-0.0-0.6
Intermittent access day 15 total locomotion1.92.04.90.5-2.01.0-1.70.8-2.2-0.40.6-1.5-1.90.91.80.9-1.8
Intermittent access total locomotion0.60.61.50.4-1.00.7-0.80.6-1.2-0.00.5-0.9-1.00.61.20.6-0.8
Intermittent access standard deviation1.81.94.50.4-2.01.1-1.70.8-2.1-0.30.6-1.5-1.90.91.50.8-1.8
Cocaine induced anxiety1.51.72.81.6-0.71.7-0.21.7-0.61.51.7-1.5-1.11.61.21.60.3
Post-drug Anxiety1.92.13.81.9-0.41.80.21.9-0.32.02.0-1.5-0.91.81.01.80.9
Baseline Anxiety0.10.10.3-0.5-0.2-0.3-0.3-0.4-0.2-0.6-0.50.2-0.0-0.4-0.1-0.4-0.5
Lifetime Intake0.00.00.10.0-0.10.1-0.10.1-0.4-0.00.0-0.1-0.10.10.30.1-0.1
Incentive Sensitization - Responses0.20.20.7-0.2-0.70.2-0.70.0-0.8-0.3-0.0-0.4-0.60.10.20.1-0.8
Incentive Sensitization - Breakpoint0.30.30.60.1-0.80.4-0.70.3-0.8-0.10.2-0.6-0.70.30.30.3-0.7
Progressive ratio test 1 active lever presses0.30.30.5-0.70.3-0.70.1-0.60.2-0.6-0.70.70.5-0.7-0.5-0.7-0.1
Progressive ratio test 1 breakpoint0.30.30.4-0.60.5-0.70.2-0.50.3-0.4-0.60.70.6-0.6-0.6-0.60.1
Progressive ratio test 1 inactive lever presses0.00.00.00.0-0.00.00.00.0-0.1-0.00.0-0.0-0.00.00.10.00.0
Progressive ratio test 2 active lever presses0.20.20.5-0.3-0.60.0-0.6-0.1-0.7-0.4-0.2-0.2-0.4-0.10.2-0.1-0.7
Progressive ratio test 2 breakpoint0.20.20.50.3-0.60.5-0.40.4-0.70.10.3-0.6-0.60.40.50.4-0.4
Progressive ratio test 2 inactive lever presses0.00.10.10.3-0.10.3-0.00.3-0.30.20.3-0.2-0.20.30.30.3-0.0
Total sessions with >9 infusions0.40.51.20.90.20.80.50.90.11.10.9-0.5-0.10.80.30.80.8
Short access day 1 total inactive lever presses0.00.00.00.0-0.20.1-0.20.1-0.2-0.00.0-0.1-0.20.10.10.1-0.2
Short access day 10 total inactive lever presses0.20.30.7-0.6-0.4-0.4-0.6-0.5-0.4-0.8-0.60.2-0.2-0.5-0.0-0.5-0.8
Short access day 1 total infusions0.60.71.31.10.00.90.31.1-0.21.11.1-0.7-0.31.00.61.00.7
Short access day 10 total infusions0.00.00.0-0.00.10.00.00.1-0.20.10.00.00.0-0.0-0.0-0.00.0
Short access total infusions0.20.20.60.60.20.50.40.6-0.00.70.6-0.3-0.00.50.10.50.5
Short access day 1 locomotion0.70.81.91.0-0.70.9-0.31.0-0.90.60.9-0.9-0.91.01.41.0-0.2
Short access day 10 total locomotion2.32.55.80.5-2.31.2-1.90.8-2.4-0.40.6-1.7-2.11.02.01.0-2.0
Short access total locomotion0.70.71.30.7-0.80.9-0.50.9-1.10.40.8-1.0-1.00.91.10.8-0.4
Compulsive drug intake0.50.41.4-0.10.9-0.50.8-0.41.20.2-0.20.70.9-0.4-0.7-0.40.9
One hour access (0.3 mA shock)0.20.20.4-0.40.5-0.60.4-0.50.4-0.3-0.50.70.6-0.6-0.4-0.50.2
One hour access (shock baseline)0.20.20.6-0.6-0.2-0.5-0.3-0.5-0.4-0.7-0.60.3-0.0-0.50.0-0.5-0.6
Number of responses in last shaping day0.10.10.30.3-0.30.4-0.20.4-0.40.20.3-0.4-0.40.40.50.4-0.2
Context. condit. distance diff. score0.30.30.5-0.50.7-0.70.5-0.60.6-0.3-0.50.70.7-0.6-0.6-0.60.3
Locomotion velocity, session 11.51.62.61.6-0.61.5-0.11.6-0.61.41.6-1.3-1.01.61.21.60.4
Locomotion distance, session 11.21.63.41.70.01.40.51.60.11.81.7-1.0-0.41.51.01.61.2
Locomotion velocity, session 24.65.48.02.7-1.72.8-0.72.8-1.62.22.8-2.7-2.22.82.62.80.1
Locomotion distance, session 22.83.96.32.5-1.02.4-0.22.5-0.92.22.5-2.1-1.62.52.12.50.6
Locomotion velocity, session 33.94.57.71.3-2.82.1-2.11.7-2.80.31.5-2.5-2.81.92.51.8-1.9
Locomotion distance, session 30.00.00.1-0.2-0.2-0.1-0.2-0.1-0.2-0.2-0.1-0.0-0.1-0.1-0.1-0.1-0.3
Stereotopy head waving bouts, day 33.64.36.31.9-2.22.4-1.52.1-2.21.12.0-2.5-2.52.22.52.2-1.1
Stereotopy head waving duration, day 33.94.77.11.8-2.52.4-1.82.1-2.50.91.9-2.6-2.72.22.62.2-1.4
Locomotion velocity, session 70.80.81.20.9-0.91.1-0.51.0-0.80.61.0-1.1-1.01.01.11.0-0.3
Locomotion distance, session 70.30.40.8-0.90.0-0.7-0.2-0.80.0-0.9-0.80.50.2-0.8-0.6-0.8-0.6
Stereotopy head waving bouts, day 70.70.82.01.20.30.90.71.10.21.41.2-0.5-0.11.00.61.01.1
Stereotopy head waving duration, day 71.11.42.81.6-0.01.30.51.5-0.11.71.6-0.9-0.51.41.01.41.0
Locomotion velocity, session 81.92.34.22.1-0.21.80.42.0-0.32.02.0-1.4-0.81.91.41.91.1
Locomotion distance, session 80.20.30.50.7-0.20.70.10.7-0.10.70.7-0.6-0.40.70.60.70.3
Degree of sensitization distance0.20.30.5-0.30.7-0.50.5-0.40.7-0.0-0.30.60.7-0.4-0.6-0.40.5
Degree of sensitization stereotypy1.01.13.30.31.6-0.41.6-0.01.60.90.10.91.4-0.2-0.9-0.21.8
Condit. Reinf. active minus inactive responses2.83.15.01.3-2.21.9-1.51.6-2.10.51.5-2.2-2.21.72.21.7-1.3
Condit. Reinf. active-inactive response ratio1.21.22.80.3-1.70.8-1.40.5-1.7-0.40.4-1.2-1.50.71.20.6-1.5
Condit. Reinf. active responses3.34.05.92.0-1.92.4-1.12.2-1.91.42.1-2.4-2.22.32.42.3-0.6
Condit. Reinf. inactive responses1.61.93.01.7-0.71.7-0.11.7-0.61.61.7-1.5-1.01.71.51.70.5
Incentive salience index mean2.22.63.81.7-1.41.9-0.81.8-1.41.21.8-1.9-1.71.91.91.9-0.4
Condit. Reinf. lever presses1.31.84.11.90.31.40.91.70.32.01.8-0.9-0.31.51.01.61.4
Time in familiar zone, hab. session 11.21.12.50.4-1.60.9-1.30.6-1.5-0.30.5-1.2-1.50.71.10.7-1.3
Time in novel zone, hab. session 10.80.72.60.61.2-0.01.30.41.21.10.40.50.90.2-0.40.21.6
Total zone transitions, hab. session 11.62.33.61.9-0.81.8-0.21.9-0.71.61.9-1.6-1.21.91.61.90.4
Total locomotion distance, hab. session 13.04.37.42.7-0.82.50.12.7-0.62.62.7-2.1-1.42.62.02.61.0
Locomotion velocity, hab. session 12.73.86.12.4-1.12.4-0.32.5-1.02.12.5-2.1-1.62.42.02.40.5
Time in familiar zone, hab. session 23.43.68.00.4-2.81.4-2.50.9-2.8-0.70.7-2.1-2.61.22.01.0-2.6
Time in novel zone, hab. session 22.52.55.9-0.12.4-1.02.2-0.42.40.9-0.31.62.1-0.7-1.5-0.62.4
Total zone transitions, hab. session 20.91.23.21.40.70.91.01.20.91.81.3-0.40.31.00.31.11.7
Total locomotion distance, hab. session 21.52.03.11.7-0.91.7-0.31.7-0.71.51.7-1.6-1.21.71.41.70.3
Locomotion velocity, hab. session 21.82.54.12.0-0.71.9-0.12.0-0.61.82.0-1.7-1.22.01.52.00.6
Novel to familiar place preference ratio2.12.26.20.32.3-0.62.2-0.12.21.20.11.31.9-0.4-1.3-0.32.5
Novelty place preference1.31.44.30.51.8-0.31.70.21.71.20.30.91.4-0.1-0.9-0.02.1
Time in novel zone, NPP test1.41.54.30.31.9-0.51.80.01.81.10.11.01.6-0.2-1.0-0.22.1
Total zone transitions, NPP test0.20.30.90.80.20.60.40.70.40.90.7-0.30.00.60.20.70.8
Total locomotion distance, NPP test0.50.71.91.10.30.80.61.00.51.41.1-0.50.00.90.31.01.1
Locomotion velocity, NPP test0.60.81.81.20.01.00.41.20.21.31.2-0.7-0.31.10.61.10.9
Pavlov. Cond. lever latency0.60.71.8-1.2-0.3-0.8-0.6-1.0-0.3-1.3-1.10.50.0-0.9-0.4-1.0-1.1
Pavlov. Cond. magazine entry latency1.52.03.70.7-1.91.3-1.51.0-1.9-0.00.9-1.7-1.91.21.71.1-1.5
Pavlov. Cond. change in total contacts0.10.10.10.3-0.30.3-0.20.2-0.20.20.3-0.3-0.30.30.30.3-0.1
Pavlov. Cond. index score0.60.81.21.1-0.51.1-0.11.1-0.50.91.1-1.0-0.71.11.01.10.2
Pavlov. Cond. latency score0.91.22.01.4-0.41.30.11.4-0.41.31.4-1.1-0.71.31.11.40.5
Pavlov. Cond. lever contacts1.01.22.61.50.11.20.51.40.11.61.5-0.8-0.31.30.81.31.1
Pavlov. Cond. magazine entry number0.40.50.8-0.50.8-0.70.6-0.60.8-0.2-0.60.80.9-0.7-0.9-0.60.5
Pavlov. Cond. intertrial magazine entries0.30.30.9-0.7-0.5-0.4-0.7-0.6-0.4-0.9-0.70.1-0.2-0.5-0.0-0.5-0.9
Pavlov. Cond. lever-magazine prob. diff.0.91.11.61.2-0.81.2-0.31.2-0.80.91.2-1.2-1.01.21.21.2-0.0
Pavlov. Cond. response bias0.70.91.30.7-1.11.0-0.80.9-1.10.30.8-1.1-1.20.91.10.9-0.6
Bone: apparent density1.93.17.02.40.51.81.32.20.62.62.3-1.2-0.22.01.12.12.0
Bone surface4.37.615.33.80.33.11.53.50.33.93.7-2.2-0.93.32.23.42.6
Bone volume4.57.615.33.80.23.11.53.50.33.93.7-2.2-0.93.32.23.42.6
Bone: connectivity density1.01.63.81.60.81.11.31.40.92.01.5-0.60.21.20.41.31.9
Bone: cortical apparent density0.81.01.9-0.71.4-1.11.1-0.91.2-0.3-0.81.31.3-1.0-1.0-0.90.8
Bone: cortical area0.71.03.30.91.30.31.60.71.21.40.80.20.80.5-0.10.51.8
Bone: cortical porosity0.70.81.11.0-0.61.0-0.21.1-0.60.81.0-1.0-0.81.01.01.00.0
Bone: cortical porosity0.60.61.31.10.10.90.51.00.11.21.1-0.6-0.20.90.61.00.8
Bone: cortical thickness0.61.12.7-0.11.6-0.71.5-0.31.60.5-0.21.01.4-0.5-0.9-0.41.5
Bone: cortical thickness0.20.30.7-0.7-0.3-0.5-0.5-0.6-0.2-0.8-0.70.3-0.0-0.6-0.3-0.6-0.7
Bone: cortical tissue density0.60.81.4-0.71.2-1.01.0-0.80.9-0.3-0.81.11.1-0.9-0.8-0.90.7
Bone: elastic displacement0.20.20.40.4-0.50.5-0.40.5-0.60.20.5-0.6-0.60.50.60.5-0.3
Bone: elastic work0.10.20.60.30.60.00.70.20.60.50.30.20.40.1-0.10.20.8
Bone: endosteal estimation0.20.41.30.40.90.01.00.30.80.70.30.30.60.2-0.20.21.1
Bone: endosteal perimeter0.71.42.41.6-0.31.40.31.5-0.41.41.5-1.2-0.71.51.31.50.6
Bone: final force0.71.23.80.51.7-0.21.70.21.71.10.30.71.3-0.0-0.60.12.0
Bone: final moment0.61.03.30.51.5-0.11.60.21.51.10.40.61.10.1-0.50.11.8
Bone: marrow area0.20.41.20.40.9-0.01.00.20.80.70.30.30.60.1-0.20.21.1
Bone: maximum diameter1.32.54.12.0-0.61.90.22.0-0.71.82.0-1.6-1.11.91.81.90.6
Bone: maximum force0.71.23.40.21.8-0.51.8-0.11.70.80.00.91.4-0.3-0.8-0.21.9
Bone: maximum moment0.61.13.10.21.6-0.41.7-0.01.60.80.10.81.3-0.2-0.7-0.21.8
Bone: minimum diameter0.30.51.31.00.40.70.80.90.31.10.9-0.40.10.80.50.81.0
Bone: periosteal estimation0.61.13.51.11.30.41.60.81.21.50.90.10.70.60.10.71.9
Bone: periosteal perimeter0.81.42.91.60.21.30.81.50.11.71.5-0.9-0.31.41.01.41.2
Bone: post-yield work0.50.61.1-0.51.0-0.80.9-0.71.0-0.2-0.61.01.0-0.8-0.8-0.70.7
Bone: stiffness1.72.76.1-0.42.4-1.32.2-0.82.50.4-0.61.72.2-1.0-1.7-1.02.1
Bone: tissue strength1.11.12.5-0.41.6-0.91.4-0.61.50.2-0.51.21.4-0.8-1.0-0.71.3
Bone: trabecular number1.93.04.92.2-0.82.1-0.02.2-0.72.02.2-1.9-1.32.11.72.20.6
Bone: trabecular spacing3.03.87.1-2.70.1-2.2-0.8-2.50.1-2.6-2.61.70.9-2.4-1.7-2.4-1.5
Bone: trabecular thickness4.55.411.93.20.62.41.72.90.73.53.0-1.6-0.42.61.62.72.6
Bone: trabecular tissue density2.73.75.6-2.01.8-2.41.0-2.21.6-1.5-2.12.42.0-2.3-2.0-2.20.4
Breakpoint value in progressive ratio session2.73.07.10.6-2.41.4-1.91.1-2.7-0.30.8-1.9-2.41.32.01.2-2.2
Distance traveled before self-admin0.10.10.40.20.40.00.50.10.60.40.10.20.4-0.0-0.30.00.7
Distance traveled after self-admin1.01.13.00.8-1.21.2-1.71.1-0.90.50.9-1.3-1.11.01.01.0-0.5
Delta time in closed arm before/after self-admin2.82.75.0-2.20.2-1.9-0.6-2.20.3-2.2-2.11.40.8-2.0-1.6-2.0-1.2
Delta time in open arm before/after self-admin0.70.71.5-0.31.2-0.70.6-0.41.20.1-0.51.01.2-0.7-0.8-0.61.0
Diff in mean of infusions in LGA sessions1.11.23.40.6-1.31.0-1.91.0-1.40.10.7-1.2-1.30.91.10.8-1.0
Extinction: sum of active levers before priming0.90.92.8-0.5-1.40.1-1.6-0.1-1.4-1.0-0.4-0.6-1.0-0.10.6-0.2-1.7
Active lever presses in extinction session 62.22.13.41.1-1.71.6-1.11.3-1.80.51.3-1.8-1.81.51.71.4-1.0
Delta distance traveled before/after self-admin1.21.22.30.8-1.31.1-1.51.0-1.30.30.9-1.3-1.41.01.21.0-0.9
Delta ambulatory time before/after self-admin1.61.82.61.2-1.31.5-1.61.5-1.30.81.3-1.6-1.51.41.31.4-0.6
Time in closed arm before self-admin0.70.82.70.51.3-0.11.70.11.21.00.40.50.90.1-0.30.21.5
Time in closed arm after self-admin0.00.00.1-0.1-0.30.1-0.2-0.2-0.0-0.10.0-0.2-0.20.0-0.20.0-0.2
Time in open arm before self-admin0.60.71.50.2-1.20.6-0.90.3-1.2-0.30.4-0.9-1.20.60.90.5-1.1
Time in open arm after self-admin0.70.71.3-0.80.9-1.10.4-0.80.8-0.6-0.91.21.0-1.0-0.7-0.90.4
Sum of active levers in priming session hrs 5-60.10.10.4-0.2-0.0-0.2-0.6-0.0-0.1-0.2-0.20.10.1-0.2-0.1-0.2-0.1
Time to tail flick, vehicle, before self-admin1.81.83.01.7-0.51.71.51.3-0.51.71.7-1.4-0.91.71.11.70.6
Time to tail flick, vehicle, after self-admin0.30.41.0-0.8-0.6-0.3-0.3-0.7-0.4-0.9-0.70.0-0.3-0.5-0.3-0.6-1.0
Time to tail flick, test, before self-admin1.41.32.61.50.01.21.61.2-0.11.61.5-0.9-0.51.40.81.40.9
Time to tail flick, test, after self-admin0.60.61.11.0-0.10.90.90.9-0.31.11.0-0.7-0.50.90.71.00.4
Delta time to tail flick, vehicle, before/after SA2.01.93.4-1.80.3-1.6-1.1-1.50.4-1.8-1.81.30.8-1.7-1.3-1.7-0.8
Delta time to tail flick, test, before/after SA0.40.30.9-0.7-0.5-0.4-0.6-0.7-0.5-0.9-0.70.1-0.2-0.5-0.0-0.5-1.0
Ambulatory time before self-admin0.10.10.2-0.10.4-0.20.4-0.10.40.2-0.10.30.4-0.2-0.3-0.20.5
Ambulatory time after self-admin0.60.61.80.6-0.90.9-1.30.8-0.70.30.7-0.9-0.80.70.70.7-0.4
Total heroin consumption1.41.72.61.1-1.41.5-1.01.3-1.50.61.2-1.6-1.61.41.51.3-0.8
Area under the delay curve1.11.22.6-0.31.6-0.91.3-0.51.60.3-0.41.21.5-0.7-1.2-0.61.4
Delay disc. indifference point, 0s delay3.84.111.00.23.1-1.12.8-0.33.11.5-0.12.02.7-0.7-2.0-0.63.3
Delay disc. indifference point, 16s delay0.10.10.20.00.4-0.10.3-0.10.40.2-0.00.30.4-0.1-0.2-0.10.4
Delay disc. indifference point, 2s delay3.03.37.3-0.42.7-1.42.2-0.82.70.7-0.72.02.5-1.1-2.1-1.02.5
Delay disc. indifference point, 24s delay0.30.30.6-0.40.7-0.40.3-0.50.7-0.2-0.30.60.7-0.5-0.8-0.40.5
Delay disc. indifference point, 4s delay0.70.72.50.51.2-0.01.20.31.31.00.40.50.90.1-0.60.21.6
Delay disc. indifference point, 8s delay1.01.01.5-1.00.9-1.20.6-1.11.0-0.6-1.11.21.1-1.2-1.2-1.10.3
Delay discount exponential model param1.01.02.30.3-1.50.8-1.20.5-1.5-0.30.4-1.2-1.40.71.20.6-1.3
Delay discount hyperbolic model param1.41.53.30.4-1.81.0-1.40.7-1.8-0.30.5-1.4-1.70.81.40.8-1.6
Fecal boli incidents, locomotor time 12.02.23.3-1.71.0-1.70.9-1.71.2-1.1-1.71.61.5-1.8-1.7-1.80.2
Change in fecal boli incidents, locomotor task1.31.22.21.5-0.11.30.21.5-0.31.51.5-1.0-0.61.41.01.40.7
Time >=10cm from walls, locomotor time 10.40.41.40.60.70.20.80.40.70.90.50.10.50.3-0.10.41.2
Bouts of movement, locomotor time 10.10.10.30.0-0.50.2-0.30.1-0.5-0.20.1-0.4-0.40.10.30.1-0.4
Total resting periods, locomotor time 10.20.20.30.3-0.60.5-0.20.4-0.50.10.3-0.6-0.50.40.50.4-0.3
Rest time, locomotor task time 10.20.20.40.6-0.30.6-0.20.5-0.40.40.6-0.6-0.40.60.50.60.1
Distance moved, locomotor task time 10.40.41.50.70.90.10.90.50.81.00.60.20.50.4-0.10.41.2
Vertical activity count, locomotor time 10.10.10.2-0.40.0-0.40.0-0.40.2-0.4-0.40.30.2-0.4-0.3-0.4-0.2
Time >=10cm from walls, locomotor time 21.11.22.0-1.11.1-1.40.5-1.20.9-0.8-1.21.41.2-1.2-1.2-1.20.3
Bouts of movement, locomotor time 21.01.01.71.3-0.41.20.01.3-0.41.21.3-1.1-0.71.21.01.30.4
Total resting periods, locomotor time 21.11.22.01.4-0.41.30.11.4-0.31.41.4-1.1-0.71.31.01.30.6
Rest time, locomotor task time 20.80.91.61.1-0.61.3-0.21.2-0.60.91.2-1.2-0.81.11.01.20.2
Distance moved, locomotor task time 21.11.32.0-1.20.9-1.40.3-1.40.8-1.1-1.31.41.0-1.3-1.1-1.3-0.0
Vertical activity count, locomotor time 21.71.83.0-1.70.7-1.70.1-1.70.6-1.6-1.71.51.0-1.7-1.3-1.7-0.4
Weight adjusted by age0.50.61.1-1.00.4-0.80.1-1.00.3-0.8-1.00.80.6-1.0-1.0-1.0-0.2
Seeking ratio, delayed vs. immediate footshock4.14.77.21.9-2.32.5-1.62.1-2.31.02.1-2.7-2.62.32.62.3-1.1
Locomotion in novel chamber0.30.40.90.0-0.90.7-1.00.2-0.9-0.40.2-0.7-0.80.30.30.3-0.8
Locomotion in novel chamber post-restriction0.50.60.90.5-0.90.8-0.90.7-0.90.20.6-1.0-0.90.70.90.7-0.5
Progressive ratio0.30.30.8-0.80.3-0.70.2-0.70.2-0.6-0.70.60.4-0.7-0.9-0.7-0.2
Food seeking constrained by brief footshock0.10.10.20.2-0.30.3-0.40.3-0.20.10.2-0.3-0.40.30.20.3-0.3
Seeking ratio, punishment vs. effort0.10.10.40.5-0.20.4-0.30.4-0.10.30.4-0.4-0.30.40.70.40.0
Run reversals in cocaine runway, females1.11.01.81.1-0.81.3-0.31.2-0.51.01.2-1.3-1.01.30.81.3-0.0
Run reversals in cocaine runway, males1.41.42.01.2-1.01.4-0.71.4-0.91.01.3-1.4-1.21.41.31.4-0.2
Latency to leave start box in cocaine runway2.02.23.41.8-0.81.8-0.01.8-0.81.61.8-1.7-1.11.81.71.80.5
Latency to leave start box in cocaine runway, F1.82.04.71.90.41.50.91.80.42.21.8-1.0-0.11.61.01.61.7
Latency to leave start box in cocaine runway, M1.61.54.1-0.1-1.90.7-1.50.2-2.0-0.90.1-1.2-1.60.41.20.3-2.0
Cd content in liver0.10.10.2-0.10.5-0.20.4-0.10.50.1-0.10.30.4-0.2-0.3-0.20.4
Co content in liver0.30.41.0-0.1-0.90.3-0.90.1-0.9-0.50.0-0.5-0.80.20.70.2-1.0
Cu content in liver0.40.51.30.90.50.60.80.80.51.10.9-0.20.20.70.30.71.1
Fe content in liver0.10.20.5-0.6-0.2-0.4-0.3-0.5-0.2-0.7-0.50.2-0.0-0.4-0.2-0.5-0.6
K content in liver0.60.61.31.10.20.80.60.90.21.11.0-0.5-0.10.90.50.90.9
Mg content in liver0.90.92.11.30.21.00.71.20.21.41.3-0.6-0.21.10.61.11.1
Mn content in liver3.84.37.72.8-0.52.50.52.7-0.52.72.7-2.0-1.22.62.02.61.3
Na content in liver0.60.61.70.21.2-0.41.2-0.11.20.60.00.71.0-0.2-0.5-0.11.3
Rb content in liver0.60.82.51.00.90.51.10.80.91.40.9-0.00.50.60.00.71.6
Se content in liver0.20.20.30.5-0.40.5-0.10.5-0.40.30.5-0.5-0.50.60.50.6-0.1
Sr content in liver0.70.71.8-1.1-0.3-0.8-0.5-1.0-0.3-1.3-1.10.50.0-0.9-0.4-0.9-1.0
Zn content in liver1.61.76.0-0.9-1.9-0.0-1.9-0.5-1.9-1.7-0.7-0.6-1.4-0.30.6-0.3-2.5