Hub : Genes

Heatr5a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000006483 0.04 0.03 2.7e-04 0.03 0.03 0.02 0.03 7.1e-04 3.4e-04 4.0e-03 5.5e-04
2 Adipose intron excision ratio chr6:69410541:69419682 0.04 0.03 3.6e-04 0.04 0.03 0.03 0.03 6.1e-05 3.2e-04 7.7e-04 2.0e-04
3 Adipose mRNA stability ENSRNOG00000006483 0.03 0.03 1.5e-03 0.02 0.02 0.01 0.02 8.6e-04 3.4e-03 8.6e-03 2.1e-03
4 BLA gene expression ENSRNOG00000006483 0.07 0.05 2.0e-03 0.05 0.03 0.04 0.04 1.6e-03 1.5e-02 5.2e-03 3.5e-03
5 LHb gene expression ENSRNOG00000006483 0.18 0.12 1.6e-03 0.14 0.14 0.09 0.12 4.2e-04 3.7e-04 4.3e-03 1.0e-03
6 Liver gene expression ENSRNOG00000006483 0.02 0.02 9.4e-03 0.01 0.01 0.01 0 2.8e-02 4.5e-02 6.3e-02 1.5e-01
7 Liver intron excision ratio chr6:69410541:69419682 0.06 0.04 3.8e-05 0.04 0.04 0.04 0.04 1.1e-05 9.0e-05 4.3e-05 1.0e-05
8 NAcc intron excision ratio chr6:69362209:69369135 0.05 0.04 2.0e-03 0.04 0.04 0.03 0.03 1.0e-03 1.2e-03 2.8e-03 3.7e-03
9 NAcc intron excision ratio chr6:69369324:69371537 0.05 0.04 1.8e-03 0.04 0.04 0.04 0.03 9.1e-04 1.0e-03 1.0e-03 2.5e-03
10 PL gene expression ENSRNOG00000006483 0.1 0.07 2.2e-06 0.07 0.1 0.09 0.08 2.2e-06 1.1e-07 1.4e-07 8.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.41.32.2-1.5-1.11.0-0.9-1.3-1.1-1.1-0.90.9-1.2
BMI without tail0.20.54.0-2.0-0.20.1-0.1-0.8-0.3-0.2-0.10.1-0.2
Body weight1.14.75.6-1.32.3-2.32.31.42.42.32.3-2.32.3
Epididymis fat weight0.30.81.0-1.0-0.80.7-0.9-1.0-0.9-0.8-0.90.9-0.9
Glucose1.32.02.8-0.11.7-1.71.41.21.41.61.4-1.41.6
Heart weight1.31.82.30.51.5-1.41.41.21.51.41.4-1.41.3
Left kidney weight0.10.21.7-1.30.2-0.20.2-0.20.40.20.2-0.20.3
Right kidney weight0.10.32.7-1.60.00.0-0.1-0.6-0.0-0.0-0.10.1-0.1
Tail length0.72.02.8-0.41.5-1.51.41.11.71.61.4-1.41.6
Length with tail2.79.912.7-0.13.4-3.43.22.73.63.43.2-3.23.5
Length without tail2.04.35.40.12.2-2.22.21.82.32.22.2-2.22.3
Liver weight, left0.20.40.5-0.30.5-0.50.70.40.50.60.7-0.70.7
Liver weight, right0.10.10.5-0.70.1-0.10.40.00.20.10.4-0.40.4
Parametrial fat weight0.30.64.5-2.1-0.30.3-0.4-0.9-0.2-0.3-0.40.4-0.2
Retroperitoneal fat weight1.13.510.2-3.2-1.51.5-1.6-2.2-1.5-1.6-1.61.6-1.6
Intraocular pressure0.30.40.7-0.80.6-0.70.70.30.60.60.7-0.70.6
Extensor digitorum longus weight1.24.65.9-1.42.3-2.32.21.32.42.42.2-2.22.3
Soleus weight1.54.25.61.52.0-2.02.12.12.42.12.1-2.12.2
Tibialis anterior weight1.55.37.0-1.12.5-2.52.31.62.62.52.3-2.32.6
Tibia length2.15.96.31.82.5-2.52.52.52.42.52.5-2.52.4
Number of licking bursts0.10.10.1-0.2-0.30.3-0.3-0.2-0.3-0.3-0.30.3-0.3
Food consumed during 24 hour testing period1.11.31.70.71.3-1.31.01.31.31.31.0-1.01.3
Times rat made contact with spout1.01.21.3-1.1-1.11.1-1.2-1.0-1.1-1.1-1.21.2-0.9
Mean time between licks in bursts0.00.00.00.20.2-0.20.20.10.10.20.2-0.20.1
Mean num. licks in bursts0.00.00.2-0.5-0.00.0-0.1-0.2-0.0-0.0-0.10.10.0
Std. dev. time between licks in bursts0.60.71.0-0.4-0.60.6-1.0-0.9-0.8-0.7-1.01.0-0.9
Water consumed over 24 hours0.10.10.5-0.70.3-0.30.20.20.40.30.2-0.20.5
Indifference point 0 sec3.65.96.81.72.5-2.42.42.52.62.52.4-2.42.5
Indifference point AUC2.83.34.22.01.8-1.81.62.12.01.71.6-1.62.0
Indifference point function ln k0.20.30.8-0.9-0.50.5-0.4-0.7-0.7-0.5-0.40.4-0.6
Indifference point function log k0.20.30.8-0.9-0.50.5-0.4-0.7-0.7-0.5-0.40.4-0.6
Delay discounting total patch changes 0 sec4.06.57.41.92.6-2.62.52.72.72.72.5-2.52.6
Delay discounting total patch changes 12 sec4.45.97.11.92.5-2.42.42.52.72.52.4-2.42.5
Delay discounting total patch changes 18 sec0.91.11.60.91.1-1.11.01.11.31.11.0-1.01.0
Delay discounting total patch changes 24 sec1.41.72.31.31.3-1.31.31.31.51.31.3-1.31.2
Delay discounting total patch changes 6 sec3.75.66.81.62.4-2.42.32.52.62.42.3-2.32.6
Delay discounting time to switch 0 sec14.622.427.1-4.8-4.74.7-4.5-5.2-4.8-4.7-4.54.5-4.8
Delay discounting water rate 0 sec4.36.88.42.82.6-2.62.42.92.62.62.4-2.42.6
Delay discounting water rate 12 sec1.42.12.80.31.4-1.51.71.31.51.51.7-1.71.5
Delay discounting water rate 18 sec2.22.93.21.31.7-1.71.71.81.81.71.7-1.71.8
Delay discounting water rate 24 sec1.82.53.30.91.6-1.61.71.61.41.71.7-1.71.8
Delay discounting water rate 6 sec5.98.69.42.53.0-2.93.03.13.02.93.0-3.02.9
Locomotor activity7.612.114.20.93.7-3.63.73.23.73.63.7-3.73.8
Locomotor testing distance4.67.69.40.12.9-2.93.12.32.92.93.1-3.13.0
Locomotor testing rearing1.82.83.5-1.31.7-1.81.90.91.71.71.9-1.91.7
Light reinforcement 10.10.11.2-1.10.1-0.00.1-0.20.30.10.1-0.10.1
Light reinforcement 20.20.22.11.40.1-0.00.10.40.30.00.1-0.1-0.1
Reaction time number correct0.30.41.1-1.1-0.50.4-0.7-0.7-0.4-0.4-0.70.7-0.4
Reaction time mean minus median4.25.57.10.4-2.52.6-2.4-1.9-2.6-2.7-2.42.4-2.6
Reaction time mean minus median AUC3.24.15.10.3-2.22.2-2.1-1.7-2.2-2.3-2.12.1-2.3
Reaction time num false alarms0.40.50.80.90.6-0.60.70.80.70.60.7-0.70.6
Reaction time num false alarms AUC0.30.40.80.90.5-0.50.50.70.60.50.5-0.50.5
Reaction time trials correct on left0.30.41.1-1.1-0.50.4-0.7-0.7-0.4-0.4-0.70.7-0.4
Reaction time trials on left0.30.40.9-0.9-0.50.4-0.7-0.6-0.4-0.4-0.70.7-0.4
Reaction time mean2.02.73.6-0.6-1.71.6-1.6-1.7-1.8-1.8-1.61.6-1.9
Reaction time mean AUC2.43.24.2-0.9-1.91.8-1.8-1.8-2.0-1.9-1.81.8-2.1
Median of all reaction times1.31.72.3-1.0-1.31.2-1.3-1.5-1.4-1.3-1.31.3-1.5
Reaction time omissions1.31.82.11.2-1.41.4-1.4-0.7-1.4-1.4-1.41.4-1.5
Reaction time false alarm rate0.81.11.81.30.9-0.91.01.21.00.91.0-1.00.9
Reaction time premature initiation rate1.21.72.00.91.3-1.21.41.31.31.31.4-1.41.3
Reaction time premature initiations0.50.70.90.20.8-0.80.80.81.00.90.8-0.80.9
Std. dev. reaction times2.93.95.40.3-2.12.1-2.0-1.6-2.3-2.2-2.02.0-2.3
Reaction time trials completed0.30.40.9-0.9-0.50.4-0.7-0.6-0.4-0.4-0.70.7-0.4
Reaction time trials AUC0.20.31.1-1.0-0.40.3-0.6-0.6-0.3-0.3-0.60.6-0.3
Social response proportion0.60.60.90.40.7-0.61.00.90.80.61.0-1.00.9
Social responses1.01.21.50.81.1-1.01.21.21.21.11.2-1.21.2
Social time1.41.82.4-0.01.5-1.41.31.11.51.51.3-1.31.5
Conditioned locomotion0.10.11.01.0-0.20.2-0.10.3-0.2-0.2-0.10.1-0.0
Cocaine response after cond. corrected0.30.30.6-0.7-0.60.6-0.3-0.6-0.7-0.6-0.30.3-0.5
Cocaine response after cond. not corrected0.50.51.9-1.4-0.60.6-0.4-0.9-0.7-0.6-0.40.4-0.7
Cocaine response before conditioning0.20.21.0-1.0-0.30.3-0.2-0.7-0.2-0.3-0.20.2-0.5
Saline control response1.21.62.10.21.3-1.31.41.11.41.31.4-1.41.3
Condit. Reinf. active minus inactive responses0.10.10.2-0.0-0.30.3-0.4-0.2-0.2-0.3-0.40.4-0.2
Condit. Reinf. active-inactive response ratio0.20.20.40.3-0.30.3-0.6-0.2-0.3-0.3-0.60.6-0.3
Condit. Reinf. active responses0.10.10.10.1-0.30.3-0.3-0.2-0.3-0.3-0.30.3-0.3
Condit. Reinf. inactive responses0.10.10.3-0.5-0.30.30.0-0.3-0.2-0.30.0-0.0-0.3
Condit. Reinf. lever presses1.01.31.70.71.2-1.21.21.11.31.21.2-1.21.1
Condit. Reinf. lever reinforcers received0.40.60.80.70.7-0.70.70.90.80.70.7-0.70.8
Pavlov. Cond. lever latency2.43.33.9-1.3-1.91.9-1.8-1.9-2.0-1.9-1.81.8-1.9
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.20.2-0.1-0.2-0.2-0.2-0.10.1-0.4
Pavlov. Cond. change in total contacts2.73.84.81.12.0-2.02.01.92.22.12.0-2.02.0
Pavlov. Cond. index score1.72.22.61.01.5-1.51.61.51.61.51.6-1.61.4
Pavlov. Cond. latency score1.62.12.41.11.5-1.51.51.51.61.51.5-1.51.4
Pavlov. Cond. lever contacts1.41.92.40.91.5-1.51.41.41.51.51.4-1.41.4
Pavlov. Cond. magazine entry number1.01.21.5-1.0-1.01.0-1.2-1.2-1.1-1.0-1.21.2-1.0
Pavlov. Cond. intertrial magazine entries0.20.30.4-0.0-0.50.5-0.6-0.3-0.5-0.5-0.60.6-0.3
Pavlov. Cond. lever-magazine prob. diff.1.72.22.61.01.5-1.51.61.51.61.51.6-1.61.4
Pavlov. Cond. response bias1.01.31.60.81.2-1.21.21.21.31.21.2-1.21.1
Conditioned reinforcement - actives3.13.13.51.81.7-1.71.81.91.81.71.8-1.81.7
Conditioned reinforcement - inactives1.41.61.90.51.3-1.31.41.21.31.31.4-1.41.3
Conditioned locomotion0.20.20.50.70.4-0.40.40.50.50.40.4-0.40.4
Intermittent access intake day 1-15 change0.20.20.5-0.70.3-0.30.30.00.60.30.3-0.30.4
Intermittent access intake escalation0.30.30.7-0.80.4-0.40.40.10.80.50.4-0.40.6
Intermittent access intake escalation 20.30.32.6-1.6-0.10.1-0.0-0.50.1-0.0-0.00.00.1
Intermitt. access day 1 inactive lever presses2.42.53.11.81.5-1.51.61.71.61.61.6-1.61.5
Intermitt. access day 15 inactive lever presses2.83.14.22.01.6-1.61.71.91.91.71.7-1.71.6
Intermitt. access escalation Index0.10.11.0-1.00.1-0.10.2-0.2-0.30.10.2-0.20.1
Intermittent access day 1 total infusions1.31.51.70.91.2-1.21.31.31.21.21.3-1.31.2
Intermittent access day 15 total infusions1.11.31.9-0.11.1-1.11.20.91.41.21.2-1.21.3
Intermittent access terminal intake (last 3 days)1.01.11.50.11.1-1.11.10.91.21.11.1-1.11.2
Intermittent access total infusions0.50.60.7-0.20.8-0.80.80.60.80.80.8-0.80.8
Intermittent access day 1 locomotion1.91.92.21.31.3-1.31.51.51.41.31.5-1.51.4
Intermittent access day 15 total locomotion0.70.81.0-0.20.9-0.91.00.70.90.91.0-1.00.9
Intermittent access total locomotion0.40.50.7-0.30.7-0.70.80.50.70.70.8-0.80.7
Intermittent access standard deviation0.50.61.50.20.7-0.70.70.71.20.80.7-0.70.9
Cocaine induced anxiety0.60.71.51.20.8-0.80.81.00.80.80.8-0.80.7
Post-drug Anxiety0.50.51.41.20.6-0.60.60.80.70.70.6-0.60.6
Baseline Anxiety1.61.72.0-0.9-1.31.3-1.4-1.3-1.4-1.3-1.41.4-1.3
Lifetime Intake0.40.50.6-0.20.7-0.70.80.50.70.70.8-0.80.8
Incentive Sensitization - Responses5.05.05.7-1.3-2.42.4-2.3-2.2-2.3-2.4-2.32.3-2.3
Incentive Sensitization - Breakpoint4.64.65.2-1.3-2.32.3-2.2-2.1-2.2-2.3-2.22.2-2.2
Progressive ratio test 1 active lever presses1.21.31.50.71.2-1.21.21.11.11.21.2-1.21.2
Progressive ratio test 1 breakpoint1.31.31.41.01.1-1.11.21.21.11.11.2-1.21.1
Progressive ratio test 1 inactive lever presses3.33.54.11.51.9-1.92.01.91.81.92.0-2.01.8
Progressive ratio test 2 active lever presses0.10.10.1-0.0-0.40.4-0.3-0.3-0.4-0.4-0.30.3-0.3
Progressive ratio test 2 breakpoint0.20.20.3-0.2-0.50.5-0.5-0.4-0.5-0.5-0.50.5-0.5
Progressive ratio test 2 inactive lever presses1.21.41.60.91.1-1.11.31.21.21.21.3-1.31.2
Total sessions with >9 infusions2.12.33.00.61.6-1.61.71.41.51.61.7-1.71.5
Short access day 1 total inactive lever presses4.24.75.8-0.22.3-2.32.41.82.12.32.4-2.42.3
Short access day 10 total inactive lever presses1.31.52.81.71.1-1.11.11.41.41.11.1-1.11.1
Short access day 1 total infusions2.12.33.0-0.01.6-1.61.71.21.41.61.7-1.71.6
Short access day 10 total infusions0.60.60.80.60.8-0.80.80.80.90.80.8-0.80.8
Short access total infusions0.20.30.4-0.30.5-0.50.60.30.30.50.6-0.60.5
Short access day 1 locomotion0.80.91.3-0.11.0-1.01.20.80.71.01.2-1.20.9
Short access day 10 total locomotion0.20.30.70.10.4-0.40.50.40.90.50.5-0.50.6
Short access total locomotion1.01.11.30.31.0-1.01.20.91.11.11.2-1.21.1
Compulsive drug intake0.50.51.01.00.7-0.70.80.70.20.60.8-0.80.5
One hour access (0.3 mA shock)2.22.53.30.21.6-1.61.71.41.81.71.7-1.71.7
One hour access (shock baseline)0.20.20.6-0.80.4-0.40.40.10.80.50.4-0.40.6
Number of responses in last shaping day0.10.10.40.50.1-0.10.10.30.70.20.1-0.10.2
Context. condit. distance diff. score0.30.41.4-1.2-0.70.7-0.3-0.7-0.6-0.7-0.30.3-0.3
Locomotion velocity, session 10.20.20.40.50.4-0.40.60.50.30.40.6-0.60.4
Locomotion distance, session 11.52.02.6-0.3-1.61.6-1.3-1.3-1.6-1.6-1.31.3-1.6
Locomotion velocity, session 20.30.31.51.2-0.50.5-0.30.1-0.6-0.5-0.30.3-0.5
Locomotion distance, session 21.52.12.90.4-1.61.6-1.5-1.2-1.6-1.6-1.51.5-1.7
Locomotion velocity, session 30.60.61.10.6-1.01.0-0.6-0.4-1.0-1.0-0.60.6-0.8
Locomotion distance, session 31.41.52.1-1.1-1.41.4-1.1-1.2-1.4-1.4-1.11.1-1.1
Stereotopy head waving bouts, day 30.30.41.31.1-0.50.5-0.6-0.0-0.6-0.5-0.60.6-0.5
Stereotopy head waving duration, day 30.20.21.81.3-0.10.1-0.10.3-0.1-0.1-0.10.1-0.1
Locomotion velocity, session 76.36.97.8-2.6-2.72.7-2.5-2.8-2.7-2.7-2.52.5-2.5
Locomotion distance, session 73.44.47.5-2.7-2.12.1-1.8-2.4-2.1-2.1-1.81.8-2.0
Stereotopy head waving bouts, day 70.60.71.41.20.8-0.80.71.00.80.80.7-0.70.8
Stereotopy head waving duration, day 70.30.42.11.50.4-0.40.20.80.40.40.2-0.20.5
Locomotion velocity, session 80.00.00.40.6-0.00.0-0.10.20.20.0-0.10.10.1
Locomotion distance, session 80.50.71.1-0.5-1.01.0-0.7-0.8-1.0-1.0-0.70.7-0.7
Degree of sensitization distance0.10.10.2-0.40.2-0.20.2-0.00.20.20.2-0.20.1
Degree of sensitization stereotypy1.01.11.30.81.1-1.11.01.11.11.11.0-1.01.1
Condit. Reinf. active minus inactive responses3.53.94.70.92.1-2.12.21.91.92.02.2-2.22.0
Condit. Reinf. active-inactive response ratio0.50.50.60.20.8-0.80.80.70.60.70.8-0.80.7
Condit. Reinf. active responses4.75.86.51.52.5-2.52.52.42.42.52.5-2.52.4
Condit. Reinf. inactive responses1.11.31.50.91.2-1.21.11.21.21.21.1-1.11.1
Incentive salience index mean4.55.56.21.52.4-2.42.52.42.32.42.5-2.52.4
Condit. Reinf. lever presses0.81.11.30.91.1-1.11.01.11.11.11.0-1.01.0
Time in familiar zone, hab. session 10.40.31.3-1.1-0.40.4-0.5-0.8-0.4-0.4-0.50.5-0.5
Time in novel zone, hab. session 10.80.71.11.10.8-0.80.91.00.70.70.9-0.90.8
Total zone transitions, hab. session 10.71.01.21.0-1.11.1-1.0-0.4-0.9-1.0-1.01.0-1.0
Total locomotion distance, hab. session 12.73.94.7-0.2-2.12.1-2.1-1.7-2.0-2.1-2.12.1-2.2
Locomotion velocity, hab. session 11.82.63.20.5-1.71.7-1.8-1.2-1.6-1.7-1.81.8-1.8
Time in familiar zone, hab. session 21.51.62.8-1.7-1.11.1-1.2-1.5-1.1-1.1-1.21.2-1.3
Time in novel zone, hab. session 23.43.44.31.91.8-1.81.82.11.71.81.8-1.81.8
Total zone transitions, hab. session 20.60.83.01.7-0.90.9-0.6-0.1-0.8-0.9-0.60.6-1.0
Total locomotion distance, hab. session 20.71.01.91.4-1.01.0-0.9-0.4-0.9-1.0-0.90.9-1.1
Locomotion velocity, hab. session 20.81.12.31.5-1.11.1-1.0-0.4-1.0-1.1-1.01.0-1.2
Novel to familiar place preference ratio0.90.91.41.11.0-1.00.71.21.01.00.7-0.71.1
Novelty place preference2.42.53.31.61.7-1.71.31.81.61.71.3-1.31.7
Time in novel zone, NPP test2.12.32.91.41.6-1.61.31.71.61.61.3-1.31.6
Total zone transitions, NPP test0.20.30.90.9-0.60.6-0.3-0.2-0.6-0.6-0.30.3-0.7
Total locomotion distance, NPP test0.40.60.90.9-0.80.8-0.7-0.3-0.8-0.8-0.70.7-0.9
Locomotion velocity, NPP test0.40.60.80.7-0.90.9-0.7-0.4-0.9-0.9-0.70.7-0.9
Pavlov. Cond. lever latency0.30.41.3-1.1-0.50.5-0.5-0.7-0.6-0.5-0.50.5-0.4
Pavlov. Cond. magazine entry latency1.11.52.30.1-1.21.2-1.3-1.1-1.3-1.3-1.31.3-1.5
Pavlov. Cond. change in total contacts0.20.21.21.10.3-0.30.30.50.20.20.3-0.30.0
Pavlov. Cond. index score0.30.30.60.7-0.50.5-0.6-0.3-0.6-0.5-0.60.6-0.8
Pavlov. Cond. latency score0.20.20.70.8-0.40.4-0.4-0.1-0.4-0.4-0.40.4-0.6
Pavlov. Cond. lever contacts0.00.00.20.40.2-0.20.10.20.30.20.1-0.1-0.0
Pavlov. Cond. magazine entry number0.81.01.8-0.61.0-1.01.00.81.21.11.0-1.01.4
Pavlov. Cond. intertrial magazine entries0.20.21.1-1.00.3-0.30.30.00.40.30.3-0.30.4
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.6-0.70.7-0.7-0.4-0.7-0.7-0.70.7-0.9
Pavlov. Cond. response bias0.40.40.80.6-0.70.7-0.6-0.4-0.7-0.7-0.60.6-0.9
Bone: apparent density1.22.02.9-0.51.4-1.41.71.01.41.41.7-1.71.5
Bone surface2.74.85.91.22.2-2.22.42.12.12.22.4-2.42.3
Bone volume2.64.45.60.62.1-2.12.41.92.12.22.4-2.42.2
Bone: connectivity density2.23.54.9-0.81.9-1.92.21.21.81.92.2-2.22.0
Bone: cortical apparent density1.62.12.8-1.6-1.41.4-1.3-1.7-1.3-1.4-1.31.3-1.5
Bone: cortical area4.56.87.91.72.6-2.62.72.72.62.72.7-2.72.8
Bone: cortical porosity0.91.01.71.30.9-0.90.81.11.01.00.8-0.81.0
Bone: cortical porosity1.11.22.31.51.0-1.00.91.21.21.10.9-0.91.1
Bone: cortical thickness0.50.81.10.00.8-0.81.10.70.80.91.1-1.10.9
Bone: cortical thickness0.00.00.1-0.2-0.20.2-0.2-0.2-0.1-0.2-0.20.2-0.1
Bone: cortical tissue density1.72.22.9-1.6-1.41.4-1.4-1.7-1.4-1.5-1.41.4-1.6
Bone: elastic displacement0.50.62.3-1.5-0.60.6-0.4-0.9-0.6-0.6-0.40.4-0.6
Bone: elastic work0.30.43.6-1.9-0.20.20.1-0.7-0.2-0.20.1-0.1-0.2
Bone: endosteal estimation2.34.98.83.02.1-2.11.92.61.92.11.9-1.92.2
Bone: endosteal perimeter4.18.411.03.32.8-2.82.73.32.82.82.7-2.73.0
Bone: final force0.00.00.1-0.00.0-0.00.30.20.10.10.3-0.30.3
Bone: final moment0.10.10.20.20.2-0.20.40.30.20.30.4-0.40.5
Bone: marrow area2.45.29.03.02.2-2.22.02.72.02.22.0-2.02.3
Bone: maximum diameter6.912.615.33.73.5-3.53.53.93.33.53.5-3.53.6
Bone: maximum force0.40.81.10.80.8-0.80.91.00.90.90.9-0.91.0
Bone: maximum moment0.50.81.20.90.8-0.80.91.00.90.90.9-0.91.1
Bone: minimum diameter2.44.55.61.82.2-2.21.92.32.12.21.9-1.92.4
Bone: periosteal estimation4.59.211.73.33.0-3.02.93.42.83.02.9-2.93.2
Bone: periosteal perimeter4.06.67.92.52.5-2.52.62.82.52.52.6-2.62.7
Bone: post-yield work0.70.91.91.40.9-0.90.61.11.10.90.6-0.61.1
Bone: stiffness0.20.41.71.30.3-0.30.40.80.30.40.4-0.40.6
Bone: tissue strength0.50.50.8-0.7-0.90.9-0.5-0.8-0.8-0.8-0.50.5-0.7
Bone: trabecular number0.81.31.8-1.21.0-1.01.40.41.11.01.4-1.41.1
Bone: trabecular spacing5.36.87.9-1.0-2.82.8-2.8-2.5-2.6-2.8-2.82.8-2.8
Bone: trabecular thickness1.31.62.1-0.01.3-1.31.41.01.21.31.4-1.41.3
Bone: trabecular tissue density0.70.91.41.1-0.90.9-1.2-0.4-0.7-0.9-1.21.2-1.0
Breakpoint value in progressive ratio session3.03.33.80.51.9-1.91.91.71.91.91.9-1.91.9
Distance traveled before self-admin0.00.00.00.20.2-0.20.20.20.20.20.2-0.20.2
Distance traveled after self-admin0.30.30.4-0.2-0.60.6-0.6-0.6-0.5-0.6-0.60.6-0.7
Delta time in closed arm before/after self-admin0.60.60.80.50.8-0.80.80.80.90.80.8-0.80.9
Delta time in open arm before/after self-admin0.00.00.1-0.30.1-0.10.10.00.10.10.1-0.10.1
Diff in mean of infusions in LGA sessions0.20.20.30.6-0.50.5-0.5-0.2-0.3-0.5-0.50.5-0.5
Extinction: sum of active levers before priming1.11.11.5-1.11.1-1.11.10.61.21.11.1-1.11.2
Active lever presses in extinction session 62.42.33.1-0.61.6-1.61.61.11.81.61.6-1.61.6
Delta distance traveled before/after self-admin0.40.40.60.0-0.70.7-0.7-0.6-0.6-0.7-0.70.7-0.8
Delta ambulatory time before/after self-admin0.50.60.80.0-0.80.8-0.8-0.7-0.8-0.8-0.80.8-0.9
Time in closed arm before self-admin2.02.32.7-0.6-1.61.6-1.6-1.5-1.6-1.6-1.61.6-1.6
Time in closed arm after self-admin0.70.70.90.1-0.90.9-0.9-0.7-0.8-0.9-0.90.9-0.9
Time in open arm before self-admin0.60.61.21.10.7-0.70.70.90.60.70.7-0.70.6
Time in open arm after self-admin0.10.10.70.80.1-0.10.10.30.10.10.1-0.10.0
Sum of active levers in priming session hrs 5-60.80.81.1-0.11.0-1.01.00.71.11.01.0-1.00.9
Time to tail flick, vehicle, before self-admin0.00.00.30.60.0-0.00.00.20.10.00.0-0.00.1
Time to tail flick, vehicle, after self-admin0.50.51.41.20.6-0.60.60.80.70.60.6-0.60.6
Time to tail flick, test, before self-admin0.10.10.3-0.6-0.20.2-0.2-0.3-0.2-0.2-0.20.2-0.2
Time to tail flick, test, after self-admin1.11.11.30.11.1-1.11.10.91.11.11.1-1.11.1
Delta time to tail flick, vehicle, before/after SA0.30.30.60.80.5-0.50.50.60.50.50.5-0.50.4
Delta time to tail flick, test, before/after SA0.00.00.10.30.1-0.10.10.10.10.10.1-0.10.1
Ambulatory time before self-admin0.00.00.00.10.1-0.10.10.10.10.10.1-0.10.1
Ambulatory time after self-admin0.60.70.8-0.6-0.80.8-0.8-0.9-0.8-0.8-0.80.8-0.9
Total heroin consumption1.92.32.60.41.6-1.61.61.41.51.61.6-1.61.6
Area under the delay curve2.82.93.51.91.6-1.61.71.91.71.61.7-1.71.7
Delay disc. indifference point, 0s delay1.31.41.81.01.1-1.21.21.31.31.21.2-1.21.3
Delay disc. indifference point, 16s delay1.81.83.11.81.2-1.21.31.51.31.21.3-1.31.2
Delay disc. indifference point, 2s delay1.01.11.30.81.0-1.01.11.11.11.01.1-1.11.1
Delay disc. indifference point, 24s delay5.14.95.52.32.2-2.22.22.32.22.22.2-2.22.1
Delay disc. indifference point, 4s delay0.00.00.30.5-0.20.2-0.10.1-0.1-0.2-0.10.10.0
Delay disc. indifference point, 8s delay0.90.91.10.71.0-0.91.01.01.00.91.0-1.01.0
Delay discount exponential model param2.02.12.8-1.7-1.41.3-1.5-1.6-1.4-1.3-1.51.5-1.4
Delay discount hyperbolic model param1.81.92.4-1.6-1.31.3-1.4-1.5-1.3-1.3-1.41.4-1.4
Fecal boli incidents, locomotor time 10.60.70.9-0.90.9-0.90.80.30.80.90.8-0.80.7
Change in fecal boli incidents, locomotor task0.00.00.1-0.4-0.20.20.0-0.1-0.1-0.20.0-0.00.0
Time >=10cm from walls, locomotor time 10.90.91.20.50.8-0.81.10.91.00.81.1-1.11.0
Bouts of movement, locomotor time 12.32.53.41.61.3-1.31.71.71.81.41.7-1.71.5
Total resting periods, locomotor time 12.52.83.51.81.5-1.51.71.81.91.51.7-1.71.6
Rest time, locomotor task time 13.94.36.42.52.1-2.11.92.12.12.11.9-1.91.7
Distance moved, locomotor task time 11.31.42.5-1.6-1.21.2-1.2-1.2-1.1-1.1-1.21.2-0.8
Vertical activity count, locomotor time 11.11.12.8-1.7-1.01.0-0.9-1.1-0.9-1.0-0.90.9-0.7
Time >=10cm from walls, locomotor time 21.21.31.8-0.01.1-1.11.30.91.21.11.3-1.31.2
Bouts of movement, locomotor time 20.30.30.60.80.6-0.60.50.60.40.50.5-0.50.5
Total resting periods, locomotor time 20.10.10.40.60.3-0.30.20.30.10.20.2-0.20.1
Rest time, locomotor task time 20.00.00.00.10.2-0.20.10.00.10.20.1-0.1-0.0
Distance moved, locomotor task time 20.20.20.40.30.5-0.50.40.60.60.50.4-0.40.6
Vertical activity count, locomotor time 20.00.00.10.1-0.30.3-0.2-0.0-0.2-0.3-0.20.2-0.1
Weight adjusted by age0.60.70.8-0.5-0.90.8-0.8-0.8-0.8-0.9-0.80.8-0.9
Seeking ratio, delayed vs. immediate footshock0.50.50.80.2-0.70.9-0.8-0.5-0.8-0.8-0.80.8-0.7
Locomotion in novel chamber2.93.64.0-1.2-2.02.0-2.0-1.8-2.0-2.0-2.02.0-1.8
Locomotion in novel chamber post-restriction0.20.21.91.4-0.00.00.10.4-0.0-0.00.1-0.1-0.1
Progressive ratio0.30.40.80.9-0.60.7-0.6-0.2-0.6-0.6-0.60.6-0.6
Food seeking constrained by brief footshock0.10.20.60.80.2-0.10.40.50.20.10.4-0.40.3
Seeking ratio, punishment vs. effort0.30.30.5-0.40.5-0.60.70.40.50.50.7-0.70.6
Run reversals in cocaine runway, females0.20.21.51.2-0.20.2-0.30.2-0.3-0.2-0.30.3-0.3
Run reversals in cocaine runway, males0.00.00.1-0.4-0.10.1-0.0-0.1-0.1-0.1-0.00.00.0
Latency to leave start box in cocaine runway0.30.30.4-0.2-0.60.6-0.6-0.5-0.6-0.6-0.60.6-0.6
Latency to leave start box in cocaine runway, F0.40.50.6-0.2-0.70.8-0.7-0.6-0.7-0.7-0.70.7-0.7
Latency to leave start box in cocaine runway, M0.00.00.00.10.1-0.10.10.10.10.10.1-0.1-0.0
Cd content in liver0.20.30.9-0.90.5-0.50.50.10.30.50.5-0.50.5
Co content in liver0.20.20.5-0.70.4-0.40.70.20.30.30.7-0.70.5
Cu content in liver0.81.01.2-0.9-1.01.0-1.0-1.0-1.0-1.1-1.01.0-0.9
Fe content in liver0.70.81.0-0.7-0.90.9-1.0-1.0-0.8-0.8-1.01.0-1.0
K content in liver3.43.44.50.8-2.02.1-2.0-1.3-1.9-2.1-2.02.0-1.9
Mg content in liver5.65.87.6-0.0-2.72.7-2.6-2.0-2.5-2.7-2.62.6-2.5
Mn content in liver0.60.75.82.4-0.10.1-0.10.80.1-0.1-0.10.10.1
Na content in liver3.23.44.5-0.8-1.81.8-2.1-1.8-1.7-1.7-2.12.1-1.9
Rb content in liver2.43.04.10.2-2.02.0-1.8-1.4-1.7-2.0-1.81.8-1.8
Se content in liver6.27.49.3-0.9-2.72.7-3.0-2.6-2.8-2.8-3.03.0-3.0
Sr content in liver0.10.10.6-0.80.0-0.0-0.1-0.30.00.2-0.10.1-0.0
Zn content in liver0.10.20.3-0.0-0.50.5-0.4-0.3-0.4-0.5-0.40.4-0.4