Sirt6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000006393 0.09 0.06 4.5e-05 0.08 0.08 0.07 0.08 5.4e-05 2.9e-05 1.3e-04 3.7e-05
2 BLA mRNA stability ENSRNOG00000006393 0.24 0.14 3.2e-06 0.04 0.08 0.09 0.07 4.2e-03 3.7e-05 2.7e-05 1.5e-04
3 Brain gene expression ENSRNOG00000006393 0.09 0.06 3.1e-07 0.06 0.06 0.06 0.06 3.5e-06 5.5e-06 1.6e-06 5.4e-06
4 Brain mRNA stability ENSRNOG00000006393 0.05 0.04 1.9e-03 0 0.01 0.02 0.01 2.9e-01 1.5e-02 3.2e-03 6.1e-02
5 LHb mRNA stability ENSRNOG00000006393 0.14 0.11 8.7e-03 0.1 0.04 0.1 0.08 1.9e-03 5.1e-02 2.5e-03 6.3e-03
6 NAcc gene expression ENSRNOG00000006393 0.05 0.04 1.2e-04 0.04 0.05 0.05 0.04 5.3e-04 2.1e-04 1.6e-04 3.5e-04
7 NAcc mRNA stability ENSRNOG00000006393 0.1 0.07 3.7e-04 0.02 0.04 0.04 0.03 1.4e-02 1.1e-03 9.6e-04 1.7e-03
8 OFC gene expression ENSRNOG00000006393 0.16 0.11 7.5e-04 0.13 0.14 0.13 0.13 6.8e-04 2.7e-04 5.9e-04 5.7e-04
9 PL gene expression ENSRNOG00000006393 0.07 0.05 4.1e-05 0.06 0.06 0.05 0.06 2.1e-05 3.8e-05 7.6e-05 2.8e-05
10 PL mRNA stability ENSRNOG00000006393 0.12 0.08 8.4e-06 0.02 0.06 0.07 0.06 8.9e-03 5.0e-05 9.8e-06 2.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail5.216.923.0-4.52.5-4.33.24.5-4.84.0-4.6-4.63.5
BMI without tail1.83.85.8-2.40.6-2.40.91.9-2.31.9-2.4-2.41.2
Body weight1.04.15.7-2.31.0-2.31.42.1-2.42.1-2.3-2.31.6
Epididymis fat weight0.20.51.00.2-1.00.1-1.0-0.70.6-0.80.30.3-1.0
Glucose0.91.41.9-1.30.6-1.30.81.3-1.41.0-1.4-1.40.8
Heart weight0.50.61.70.4-1.00.3-0.9-0.80.8-1.30.50.4-1.0
Left kidney weight0.10.40.90.80.90.90.5-0.10.40.30.70.80.5
Right kidney weight1.23.44.92.2-0.82.2-1.2-1.92.2-1.82.22.2-1.3
Tail length2.68.010.82.6-2.62.4-2.9-3.33.1-2.82.82.7-3.0
Length with tail1.55.47.42.6-1.52.5-1.8-2.62.7-2.12.62.7-1.9
Length without tail0.10.30.60.70.70.80.6-0.10.30.10.60.70.6
Liver weight, left1.93.14.7-2.20.6-2.11.21.9-2.01.4-2.2-2.11.2
Liver weight, right1.42.33.1-1.61.1-1.51.31.8-1.71.6-1.6-1.51.4
Parametrial fat weight0.40.71.10.7-1.00.6-1.0-1.01.0-0.70.70.7-1.0
Retroperitoneal fat weight0.41.52.7-1.6-0.0-1.70.41.0-1.41.1-1.6-1.60.5
Intraocular pressure0.40.61.7-0.4-1.3-0.6-0.9-0.50.1-0.8-0.3-0.4-1.2
Extensor digitorum longus weight3.514.222.0-4.71.1-4.72.33.9-4.32.9-4.7-4.62.2
Soleus weight7.221.127.9-5.02.9-4.83.75.2-5.34.5-5.1-4.93.9
Tibialis anterior weight0.72.53.6-1.71.1-1.61.31.9-1.81.6-1.7-1.61.4
Tibia length0.82.12.81.4-1.31.3-1.5-1.71.7-1.51.41.4-1.5
Number of licking bursts0.40.40.9-0.8-1.0-0.9-0.5-0.2-0.3-0.3-0.7-0.8-0.6
Food consumed during 24 hour testing period0.40.50.6-0.80.4-0.70.50.7-0.80.7-0.8-0.80.6
Times rat made contact with spout0.20.30.7-0.7-0.4-0.8-0.10.3-0.4-0.3-0.7-0.8-0.2
Mean time between licks in bursts3.34.66.52.0-2.01.8-2.1-2.62.4-2.22.12.1-2.3
Mean num. licks in bursts0.10.10.20.20.50.30.30.30.0-0.10.20.10.3
Std. dev. time between licks in bursts0.80.92.11.40.41.5-0.1-0.81.0-0.31.31.30.0
Water consumed over 24 hours0.70.82.0-0.21.4-0.11.21.0-0.81.1-0.3-0.31.3
Indifference point 0 sec0.10.20.3-0.40.5-0.40.50.6-0.60.4-0.4-0.50.5
Indifference point AUC0.91.01.41.0-0.81.0-0.9-1.21.2-1.01.11.1-0.9
Indifference point function ln k0.20.30.5-0.70.2-0.70.40.5-0.60.5-0.7-0.70.4
Indifference point function log k0.20.30.5-0.70.2-0.70.40.5-0.60.5-0.7-0.70.4
Delay discounting total patch changes 0 sec0.10.20.3-0.40.3-0.50.40.5-0.50.3-0.5-0.50.4
Delay discounting total patch changes 12 sec0.30.41.0-0.9-0.3-1.0-0.10.5-0.7-0.1-0.8-1.0-0.1
Delay discounting total patch changes 18 sec0.81.01.51.0-0.71.0-0.9-1.21.1-0.91.11.1-0.8
Delay discounting total patch changes 24 sec0.10.10.20.40.10.4-0.2-0.30.3-0.30.40.4-0.1
Delay discounting total patch changes 6 sec0.10.20.40.4-0.30.3-0.3-0.50.4-0.60.40.3-0.4
Delay discounting time to switch 0 sec1.62.44.0-1.01.9-0.81.91.9-1.61.5-1.1-1.12.0
Delay discounting water rate 0 sec0.40.61.8-0.4-1.3-0.6-1.0-0.70.2-0.8-0.3-0.5-1.2
Delay discounting water rate 12 sec1.01.53.4-1.8-0.6-1.9-0.00.7-1.20.5-1.7-1.7-0.0
Delay discounting water rate 18 sec1.41.85.4-0.8-2.3-1.1-1.8-1.00.2-1.3-0.6-0.8-2.0
Delay discounting water rate 24 sec1.82.44.9-1.8-2.2-2.2-1.3-0.2-0.7-1.0-1.6-1.9-1.6
Delay discounting water rate 6 sec1.01.44.0-0.1-2.0-0.3-1.5-1.20.7-1.70.1-0.1-1.8
Locomotor activity2.74.37.42.7-0.32.7-1.0-2.02.3-1.42.72.7-1.0
Locomotor testing distance1.52.54.22.0-0.42.0-1.0-1.71.8-0.92.02.0-0.9
Locomotor testing rearing0.00.10.2-0.0-0.4-0.0-0.5-0.30.10.10.00.0-0.3
Light reinforcement 14.58.310.73.2-1.73.0-2.2-3.23.3-3.03.33.1-2.4
Light reinforcement 21.31.72.31.5-0.81.4-1.1-1.51.5-1.11.51.5-1.1
Reaction time number correct0.60.92.1-1.3-0.5-1.4-0.10.5-0.90.0-1.3-1.4-0.2
Reaction time mean minus median0.70.91.51.1-0.41.1-0.8-1.11.1-0.11.11.2-0.7
Reaction time mean minus median AUC0.60.82.10.81.31.00.70.10.21.40.70.90.9
Reaction time num false alarms0.00.10.1-0.3-0.2-0.4-0.10.0-0.2-0.3-0.3-0.3-0.1
Reaction time num false alarms AUC0.10.20.5-0.6-0.5-0.7-0.30.1-0.3-0.1-0.6-0.6-0.2
Reaction time trials correct on left0.60.92.1-1.3-0.5-1.4-0.10.5-0.90.0-1.3-1.4-0.2
Reaction time trials on left0.60.82.0-1.3-0.5-1.4-0.10.5-0.90.1-1.2-1.3-0.1
Reaction time mean0.40.51.50.51.10.70.60.2-0.01.20.40.60.8
Reaction time mean AUC0.40.51.70.41.10.50.60.3-0.11.30.30.40.8
Median of all reaction times0.60.82.3-0.11.40.11.00.8-0.61.5-0.2-0.01.2
Reaction time omissions0.20.30.60.7-0.00.7-0.3-0.60.60.20.70.7-0.2
Reaction time false alarm rate0.00.00.00.00.20.10.10.1-0.00.10.00.10.2
Reaction time premature initiation rate1.01.42.90.6-1.50.4-1.3-1.31.1-1.70.70.6-1.5
Reaction time premature initiations1.01.43.8-0.1-2.0-0.4-1.5-1.20.7-1.80.1-0.1-1.7
Std. dev. reaction times0.30.51.00.90.41.0-0.1-0.60.60.60.81.0-0.0
Reaction time trials completed0.60.82.0-1.3-0.5-1.4-0.10.5-0.90.1-1.2-1.3-0.1
Reaction time trials AUC0.60.92.2-1.4-0.7-1.5-0.20.4-0.9-0.1-1.3-1.4-0.3
Social response proportion0.60.61.11.0-0.01.1-0.2-0.60.9-0.71.01.1-0.3
Social responses6.38.113.13.5-0.93.5-1.7-2.83.4-2.43.53.6-1.7
Social time0.60.81.3-1.10.2-1.10.50.9-1.00.7-1.1-1.10.6
Conditioned locomotion1.61.94.3-1.9-0.4-2.10.21.1-1.50.5-1.9-2.00.1
Cocaine response after cond. corrected4.34.88.8-2.90.2-3.01.02.0-2.51.2-2.8-3.00.9
Cocaine response after cond. not corrected4.65.19.6-3.00.1-3.11.02.1-2.61.2-3.0-3.10.9
Cocaine response before conditioning0.40.50.90.9-0.10.9-0.4-0.60.8-0.30.90.9-0.3
Saline control response0.10.10.2-0.4-0.2-0.5-0.10.2-0.30.0-0.4-0.4-0.1
Condit. Reinf. active minus inactive responses2.22.74.01.2-1.91.0-1.8-1.91.7-1.91.31.2-2.0
Condit. Reinf. active-inactive response ratio0.70.82.4-0.4-1.6-0.6-1.1-0.70.3-1.1-0.2-0.4-1.3
Condit. Reinf. active responses2.02.73.51.7-1.21.6-1.4-1.91.9-1.81.81.7-1.6
Condit. Reinf. inactive responses1.11.42.41.5-0.11.5-0.5-1.11.3-1.01.51.5-0.5
Condit. Reinf. lever presses2.12.93.91.4-1.71.2-1.9-2.01.8-1.81.51.4-2.0
Condit. Reinf. lever reinforcers received1.62.23.31.4-1.31.2-1.4-1.71.6-1.81.41.3-1.6
Pavlov. Cond. lever latency0.71.01.4-1.20.5-1.10.91.0-1.10.7-1.2-1.20.8
Pavlov. Cond. magazine entry latency0.40.51.00.9-0.11.0-0.5-0.70.8-0.00.91.0-0.3
Pavlov. Cond. change in total contacts0.81.11.41.1-0.81.0-1.0-1.11.2-1.01.11.1-1.0
Pavlov. Cond. index score0.81.01.51.1-0.71.1-1.0-1.11.2-0.61.21.2-0.8
Pavlov. Cond. latency score0.70.91.51.2-0.41.2-0.8-1.01.1-0.41.21.2-0.6
Pavlov. Cond. lever contacts0.71.01.20.9-0.90.8-1.1-1.11.1-0.91.01.0-1.1
Pavlov. Cond. magazine entry number0.70.91.7-1.20.2-1.20.71.0-1.10.3-1.2-1.30.5
Pavlov. Cond. intertrial magazine entries0.50.61.4-1.1-0.2-1.10.20.4-0.90.1-1.0-1.20.1
Pavlov. Cond. lever-magazine prob. diff.0.81.01.61.2-0.51.2-0.9-1.11.2-0.51.21.3-0.7
Pavlov. Cond. response bias1.62.22.91.5-1.31.3-1.6-1.71.7-1.31.51.5-1.5
Conditioned reinforcement - actives2.22.23.11.7-0.71.7-1.0-1.71.8-1.31.71.7-1.1
Conditioned reinforcement - inactives0.80.92.0-1.3-0.5-1.40.00.6-0.90.3-1.2-1.4-0.0
Conditioned locomotion6.78.010.83.0-1.92.8-2.3-3.23.3-2.83.13.0-2.5
Intermittent access intake day 1-15 change5.65.58.02.2-2.12.0-2.3-2.82.7-2.42.32.2-2.4
Intermittent access intake escalation5.85.78.61.7-2.81.4-2.8-2.92.5-2.61.91.7-2.9
Intermittent access intake escalation 27.17.010.22.1-2.91.8-3.0-3.22.8-2.92.22.1-3.1
Intermitt. access day 1 inactive lever presses0.60.71.60.3-1.20.1-0.9-0.90.7-1.30.30.3-1.1
Intermitt. access day 15 inactive lever presses0.40.40.80.3-0.90.2-0.7-0.80.7-0.90.30.2-0.8
Intermitt. access escalation Index0.80.72.20.21.50.41.10.7-0.41.20.10.21.2
Intermittent access day 1 total infusions0.10.20.7-0.30.4-0.20.30.3-0.30.8-0.3-0.30.4
Intermittent access day 15 total infusions1.41.62.80.9-1.50.8-1.5-1.71.4-1.01.00.9-1.5
Intermittent access terminal intake (last 3 days)0.80.91.51.0-0.61.0-0.9-1.21.1-0.51.01.0-0.8
Intermittent access total infusions0.10.10.30.1-0.50.1-0.5-0.60.4-0.00.20.1-0.5
Intermittent access day 1 locomotion0.20.20.40.2-0.60.2-0.6-0.60.5-0.20.30.2-0.6
Intermittent access day 15 total locomotion2.72.94.61.5-1.61.4-1.8-2.21.9-1.51.61.5-1.8
Intermittent access total locomotion0.70.81.40.9-0.70.9-0.9-1.21.1-0.50.90.9-0.9
Intermittent access standard deviation2.72.94.31.5-1.61.4-1.7-2.11.9-1.81.61.5-1.8
Cocaine induced anxiety0.91.02.41.40.51.6-0.0-0.61.0-0.41.41.50.1
Post-drug Anxiety1.01.12.51.41.11.60.4-0.30.80.11.31.50.6
Baseline Anxiety0.10.10.2-0.2-0.5-0.3-0.3-0.30.1-0.2-0.1-0.2-0.4
Lifetime Intake0.00.00.20.1-0.10.2-0.2-0.30.20.40.10.1-0.1
Incentive Sensitization - Responses0.40.40.60.4-0.70.3-0.7-0.80.7-0.70.40.4-0.7
Incentive Sensitization - Breakpoint0.40.40.60.5-0.60.5-0.6-0.80.8-0.70.60.6-0.7
Progressive ratio test 1 active lever presses0.20.20.4-0.6-0.1-0.6-0.10.2-0.40.5-0.6-0.70.0
Progressive ratio test 1 breakpoint0.20.30.5-0.60.0-0.60.10.3-0.50.7-0.6-0.70.2
Progressive ratio test 1 inactive lever presses0.00.00.00.00.00.00.0-0.10.00.10.00.00.0
Progressive ratio test 2 active lever presses0.20.20.50.2-0.70.2-0.7-0.70.5-0.40.30.2-0.6
Progressive ratio test 2 breakpoint0.20.30.50.5-0.30.6-0.4-0.70.7-0.30.60.6-0.4
Progressive ratio test 2 inactive lever presses0.00.00.10.30.00.3-0.0-0.20.30.00.30.2-0.0
Total sessions with >9 infusions0.30.30.80.50.90.60.50.10.10.80.40.50.6
Short access day 1 total inactive lever presses0.00.00.10.1-0.20.1-0.3-0.20.10.00.10.1-0.2
Short access day 10 total inactive lever presses0.20.20.7-0.1-0.9-0.3-0.7-0.40.2-0.6-0.1-0.2-0.7
Short access day 1 total infusions0.40.40.90.70.80.80.2-0.10.30.90.60.70.5
Short access day 10 total infusions0.00.00.4-0.00.10.1-0.1-0.20.00.7-0.0-0.00.0
Short access total infusions0.20.21.00.30.70.40.20.00.01.00.20.30.5
Short access day 1 locomotion0.50.61.11.0-0.11.0-0.3-0.90.9-0.01.00.9-0.3
Short access day 10 total locomotion3.53.85.71.7-1.91.5-1.9-2.42.2-2.01.81.7-2.1
Short access total locomotion0.60.71.01.0-0.31.0-0.6-1.01.0-0.11.01.0-0.5
Compulsive drug intake0.70.71.4-0.70.8-0.71.01.2-1.00.4-0.7-0.70.9
One hour access (0.3 mA shock)0.20.30.4-0.60.2-0.60.40.4-0.50.6-0.6-0.70.3
One hour access (shock baseline)0.10.10.4-0.2-0.6-0.3-0.5-0.40.1-0.1-0.2-0.3-0.5
Number of responses in last shaping day0.10.10.20.4-0.10.4-0.3-0.40.40.00.40.4-0.2
Context. condit. distance diff. score0.30.30.5-0.70.2-0.70.40.5-0.60.6-0.7-0.60.4
Locomotion velocity, session 10.80.92.11.30.61.50.1-0.50.9-0.31.31.30.2
Locomotion distance, session 10.60.81.91.01.41.20.80.10.30.30.90.90.9
Locomotion velocity, session 23.13.77.92.70.42.8-0.5-1.62.1-1.02.62.6-0.3
Locomotion distance, session 21.62.25.32.10.92.30.1-1.01.5-0.72.02.00.2
Locomotion velocity, session 35.05.87.82.5-1.72.4-2.1-2.72.8-2.42.62.6-2.2
Locomotion distance, session 30.00.00.10.0-0.3-0.0-0.2-0.10.2-0.30.00.0-0.3
Stereotopy head waving bouts, day 33.64.36.42.5-0.82.5-1.4-2.22.4-1.62.52.5-1.4
Stereotopy head waving duration, day 34.25.17.02.6-1.12.6-1.7-2.52.6-1.92.72.6-1.7
Locomotion velocity, session 70.70.71.21.1-0.11.1-0.4-0.81.0-0.81.11.0-0.4
Locomotion distance, session 70.20.20.4-0.5-0.6-0.6-0.30.1-0.2-0.3-0.5-0.5-0.4
Stereotopy head waving bouts, day 70.40.51.30.61.10.80.80.30.10.80.50.60.9
Stereotopy head waving duration, day 70.60.71.41.01.11.20.6-0.10.40.50.91.00.8
Locomotion velocity, session 81.01.12.61.41.21.60.6-0.30.80.41.31.40.8
Locomotion distance, session 80.10.20.40.60.40.60.2-0.20.3-0.20.50.50.2
Degree of sensitization distance0.30.30.5-0.60.4-0.60.50.6-0.70.6-0.6-0.60.5
Degree of sensitization stereotypy1.82.03.4-0.91.7-0.71.71.6-1.41.8-1.0-0.91.8
Condit. Reinf. active minus inactive responses3.33.75.12.1-1.12.1-1.4-2.22.3-1.92.22.1-1.5
Condit. Reinf. active-inactive response ratio1.92.02.81.2-1.41.1-1.5-1.71.6-1.61.31.2-1.6
Condit. Reinf. active responses2.93.55.82.4-0.42.4-0.9-1.92.2-1.52.42.4-0.9
Condit. Reinf. inactive responses0.91.02.41.40.71.50.2-0.71.0-0.31.41.40.2
Incentive salience index mean1.82.23.81.9-0.22.0-0.6-1.51.7-1.11.91.9-0.6
Condit. Reinf. lever presses0.71.02.50.91.61.21.10.20.30.70.80.91.2
Time in familiar zone, hab. session 11.91.72.31.2-1.21.1-1.3-1.51.5-1.51.31.2-1.4
Time in novel zone, hab. session 11.21.22.6-0.41.6-0.21.41.1-0.91.4-0.5-0.51.6
Total zone transitions, hab. session 10.91.33.11.60.61.80.1-0.81.1-0.51.61.60.1
Total locomotion distance, hab. session 11.52.25.42.11.32.30.5-0.61.3-0.31.92.00.6
Locomotion velocity, hab. session 11.62.25.32.10.82.30.0-1.01.5-0.72.02.10.1
Time in familiar zone, hab. session 25.55.87.52.0-2.41.8-2.6-2.72.6-2.72.22.1-2.7
Time in novel zone, hab. session 24.24.26.3-1.52.3-1.32.32.4-2.22.4-1.7-1.62.5
Total zone transitions, hab. session 20.71.03.40.41.80.61.40.8-0.40.80.20.21.5
Total locomotion distance, hab. session 20.91.22.71.50.61.60.0-0.71.1-0.81.51.40.0
Locomotion velocity, hab. session 21.01.33.21.60.91.80.3-0.61.0-0.61.51.50.3
Novel to familiar place preference ratio3.73.96.5-1.32.4-1.02.32.3-1.92.5-1.4-1.32.5
Novelty place preference2.32.44.4-0.82.0-0.61.91.8-1.42.0-1.0-0.92.1
Time in novel zone, NPP test2.52.64.5-1.02.0-0.71.91.9-1.62.1-1.1-1.02.1
Total zone transitions, NPP test0.10.20.80.30.90.40.60.3-0.10.10.20.20.7
Total locomotion distance, NPP test0.30.51.60.51.30.60.90.5-0.10.30.40.31.0
Locomotion velocity, NPP test0.30.41.10.71.00.90.70.20.20.00.60.60.7
Pavlov. Cond. lever latency0.30.41.3-0.5-1.2-0.7-0.8-0.40.0-0.5-0.4-0.5-0.9
Pavlov. Cond. magazine entry latency2.22.83.91.6-1.31.5-1.5-2.01.9-1.81.71.7-1.6
Pavlov. Cond. change in total contacts0.10.10.10.3-0.00.3-0.0-0.20.3-0.30.30.3-0.1
Pavlov. Cond. index score0.40.51.11.00.31.00.0-0.50.7-0.30.90.90.1
Pavlov. Cond. latency score0.50.61.51.10.71.20.2-0.40.7-0.11.01.10.3
Pavlov. Cond. lever contacts0.50.61.50.81.21.00.80.20.30.40.70.80.9
Pavlov. Cond. magazine entry number0.50.60.8-0.80.5-0.80.60.9-0.90.8-0.8-0.80.6
Pavlov. Cond. intertrial magazine entries0.30.30.9-0.1-1.0-0.3-0.7-0.60.2-0.7-0.1-0.1-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.61.20.11.2-0.2-0.81.0-0.51.21.2-0.2
Pavlov. Cond. response bias0.81.01.31.1-0.51.1-0.7-1.11.2-1.01.11.1-0.8
Bone: apparent density1.01.75.01.22.21.51.60.60.10.91.01.21.6
Bone surface2.13.78.62.22.92.61.90.30.71.01.92.22.0
Bone volume2.23.78.62.22.92.61.90.30.71.01.92.22.0
Bone: connectivity density0.81.23.90.52.00.81.61.0-0.31.00.30.51.6
Bone: cortical apparent density1.01.32.7-1.20.6-1.20.81.0-1.31.6-1.3-1.11.0
Bone: cortical area0.91.33.2-0.21.80.01.61.1-0.81.5-0.3-0.11.7
Bone: cortical porosity0.50.51.11.00.11.0-0.2-0.60.8-0.31.01.0-0.1
Bone: cortical porosity0.30.30.80.60.90.70.60.10.20.40.50.60.7
Bone: cortical thickness1.11.82.6-1.01.4-0.91.51.5-1.41.6-1.1-1.01.6
Bone: cortical thickness0.20.20.5-0.3-0.7-0.4-0.5-0.30.0-0.5-0.2-0.3-0.6
Bone: cortical tissue density0.71.02.2-1.10.5-1.00.60.8-1.11.5-1.1-1.00.8
Bone: elastic displacement0.20.30.40.6-0.30.6-0.4-0.50.6-0.40.60.7-0.3
Bone: elastic work0.20.30.6-0.20.8-0.10.70.6-0.40.7-0.2-0.10.8
Bone: endosteal estimation0.30.61.2-0.31.1-0.11.00.8-0.61.1-0.3-0.21.1
Bone: endosteal perimeter0.40.71.71.20.71.30.3-0.40.80.21.11.30.4
Bone: final force1.22.03.7-0.71.9-0.51.81.6-1.31.6-0.8-0.71.9
Bone: final moment1.01.63.2-0.61.8-0.41.71.4-1.21.5-0.7-0.61.7
Bone: marrow area0.30.61.2-0.31.1-0.21.00.8-0.61.1-0.4-0.21.1
Bone: maximum diameter0.71.33.11.60.81.80.2-0.81.10.11.51.70.3
Bone: maximum force1.22.13.4-0.91.8-0.71.81.6-1.41.8-1.1-0.91.8
Bone: maximum moment1.01.83.0-0.81.7-0.61.71.5-1.31.7-1.0-0.81.7
Bone: minimum diameter0.20.41.00.41.00.50.80.3-0.00.70.30.40.9
Bone: periosteal estimation0.71.43.5-0.11.90.21.61.1-0.71.6-0.2-0.01.7
Bone: periosteal perimeter0.40.71.60.91.31.10.80.00.30.80.81.00.9
Bone: post-yield work0.60.81.0-1.00.6-0.90.80.8-1.01.0-1.0-0.90.8
Bone: stiffness2.64.15.5-1.82.0-1.62.22.3-2.22.2-1.9-1.82.2
Bone: tissue strength1.71.72.8-1.21.1-1.11.21.4-1.41.7-1.3-1.11.4
Bone: trabecular number1.01.63.81.80.92.00.3-0.61.2-0.41.71.80.3
Bone: trabecular spacing1.41.83.9-1.7-1.7-2.0-1.00.1-0.8-0.5-1.5-1.7-1.1
Bone: trabecular thickness2.43.08.01.62.82.02.10.70.31.31.31.62.1
Bone: trabecular tissue density2.13.05.4-2.30.1-2.30.61.4-1.91.6-2.2-2.20.8
Breakpoint value in progressive ratio session4.24.77.12.0-2.01.9-2.2-2.72.4-2.02.12.0-2.2
Distance traveled before self-admin0.20.20.4-0.20.6-0.20.60.6-0.50.6-0.3-0.20.6
Distance traveled after self-admin1.01.12.11.1-0.41.4-1.3-0.91.1-1.01.21.1-0.7
Delta time in closed arm before/after self-admin1.31.33.0-1.5-1.4-1.7-0.60.3-0.8-0.5-1.3-1.4-0.8
Delta time in open arm before/after self-admin1.11.01.5-1.00.9-0.60.61.2-1.11.2-1.1-1.01.1
Diff in mean of infusions in LGA sessions1.51.72.81.2-0.91.5-1.7-1.41.4-1.11.21.2-1.1
Extinction: sum of active levers before priming1.41.43.00.5-1.60.6-1.7-1.41.1-1.30.60.5-1.6
Active lever presses in extinction session 62.52.43.51.8-0.81.5-1.1-1.81.9-1.41.81.8-1.2
Delta distance traveled before/after self-admin1.41.51.71.3-0.71.3-1.3-1.31.3-1.21.31.3-1.1
Delta ambulatory time before/after self-admin1.61.73.11.5-0.31.8-1.2-1.31.4-1.01.51.5-0.8
Time in closed arm before self-admin1.11.32.5-0.41.5-0.61.61.2-1.01.4-0.6-0.51.4
Time in closed arm after self-admin0.00.00.20.1-0.2-0.20.0-0.00.1-0.50.10.1-0.3
Time in open arm before self-admin1.11.22.30.9-1.00.7-0.8-1.21.2-1.51.00.9-1.2
Time in open arm after self-admin0.60.61.1-1.00.2-0.80.30.8-0.90.7-1.0-1.10.5
Sum of active levers in priming session hrs 5-60.10.10.3-0.1-0.10.2-0.6-0.1-0.10.3-0.1-0.2-0.1
Time to tail flick, vehicle, before self-admin0.90.92.11.40.80.61.2-0.50.80.21.31.40.3
Time to tail flick, vehicle, after self-admin0.40.41.3-0.1-1.0-0.5-0.4-0.40.3-1.2-0.0-0.1-0.9
Time to tail flick, test, before self-admin0.70.71.91.01.10.61.4-0.10.50.40.91.00.8
Time to tail flick, test, after self-admin0.30.30.60.80.60.50.7-0.30.40.20.70.80.3
Delta time to tail flick, vehicle, before/after SA0.90.91.7-1.3-1.0-0.9-1.00.4-0.7-0.5-1.2-1.3-0.5
Delta time to tail flick, test, before/after SA0.40.31.0-0.1-1.0-0.4-0.7-0.50.2-0.6-0.1-0.1-0.9
Ambulatory time before self-admin0.20.20.4-0.30.4-0.30.30.5-0.40.6-0.4-0.30.4
Ambulatory time after self-admin0.60.61.30.8-0.31.2-1.0-0.70.8-0.60.80.8-0.5
Total heroin consumption1.51.82.61.6-0.51.6-1.0-1.61.6-0.81.61.6-0.9
Area under the delay curve1.81.92.7-1.21.4-1.11.41.6-1.51.5-1.3-1.21.5
Delay disc. indifference point, 0s delay6.87.311.9-1.93.1-1.53.13.2-2.73.2-2.1-1.93.4
Delay disc. indifference point, 16s delay0.10.10.2-0.20.5-0.20.40.4-0.40.4-0.3-0.30.4
Delay disc. indifference point, 2s delay5.15.68.2-2.02.3-1.72.42.8-2.62.9-2.1-2.02.7
Delay disc. indifference point, 24s delay0.40.40.7-0.60.6-0.60.70.6-0.70.6-0.6-0.80.6
Delay disc. indifference point, 4s delay1.21.32.7-0.51.6-0.31.41.3-1.01.3-0.6-0.61.6
Delay disc. indifference point, 8s delay0.80.81.4-1.20.1-1.20.41.0-1.00.3-1.2-1.10.4
Delay discount exponential model param1.61.72.31.1-1.31.0-1.3-1.51.5-1.41.21.2-1.4
Delay discount hyperbolic model param2.32.53.41.4-1.51.2-1.5-1.91.8-1.71.51.4-1.7
Fecal boli incidents, locomotor time 11.61.73.2-1.8-0.0-1.80.41.2-1.51.0-1.7-1.70.3
Change in fecal boli incidents, locomotor task0.70.71.51.10.71.20.4-0.30.70.11.01.20.6
Time >=10cm from walls, locomotor time 10.60.61.5-0.11.20.01.00.7-0.51.0-0.2-0.21.1
Bouts of movement, locomotor time 10.10.10.20.3-0.30.2-0.3-0.50.4-0.30.30.3-0.5
Total resting periods, locomotor time 10.20.20.30.5-0.20.5-0.3-0.50.5-0.10.50.4-0.4
Rest time, locomotor task time 10.10.10.30.50.10.50.0-0.40.40.10.50.5-0.0
Distance moved, locomotor task time 10.60.61.6-0.11.30.01.10.8-0.60.8-0.2-0.21.2
Vertical activity count, locomotor time 10.10.10.1-0.3-0.2-0.40.00.2-0.2-0.2-0.3-0.3-0.2
Time >=10cm from walls, locomotor time 21.01.01.9-1.30.2-1.30.50.9-1.20.7-1.3-1.40.6
Bouts of movement, locomotor time 20.50.61.31.00.61.20.2-0.40.7-0.41.01.00.3
Total resting periods, locomotor time 20.50.61.41.00.81.20.3-0.30.7-0.21.01.00.4
Rest time, locomotor task time 20.50.51.21.00.41.1-0.1-0.60.8-0.01.00.9-0.1
Distance moved, locomotor task time 20.70.81.8-1.2-0.2-1.30.30.8-1.00.3-1.2-1.30.3
Vertical activity count, locomotor time 20.91.02.5-1.4-0.7-1.60.00.6-0.90.2-1.3-1.3-0.1
Weight adjusted by age0.30.30.8-0.8-0.3-0.90.00.4-0.40.5-0.8-0.7-0.0
Seeking ratio, delayed vs. immediate footshock4.14.77.02.6-0.92.6-1.5-2.22.5-1.72.62.6-1.6
Locomotion in novel chamber0.40.50.90.6-0.60.5-0.7-0.90.8-0.90.70.5-1.0
Locomotion in novel chamber post-restriction0.50.61.00.9-0.40.9-0.7-1.00.9-0.30.91.0-0.5
Progressive ratio0.10.20.4-0.6-0.3-0.60.10.4-0.3-0.2-0.5-0.5-0.0
Food seeking constrained by brief footshock0.10.10.40.4-0.10.4-0.2-0.30.3-0.70.40.3-0.3
Seeking ratio, punishment vs. effort0.10.10.20.40.10.4-0.1-0.30.2-0.10.40.3-0.1
Run reversals in cocaine runway, females0.80.81.61.20.21.30.0-0.50.9-1.21.21.1-0.3
Run reversals in cocaine runway, males1.11.12.11.40.01.4-0.5-1.01.1-0.61.41.4-0.4
Latency to leave start box in cocaine runway1.11.22.71.50.71.60.1-0.91.10.21.41.50.1
Latency to leave start box in cocaine runway, F1.11.23.60.91.91.21.20.20.11.40.70.81.4
Latency to leave start box in cocaine runway, M2.92.84.31.1-2.00.9-1.9-1.91.8-2.01.31.2-2.1
Cd content in liver0.20.20.4-0.30.4-0.30.40.5-0.50.6-0.4-0.30.4
Co content in liver0.60.71.10.6-1.00.4-0.9-0.90.8-1.00.60.5-1.0
Cu content in liver0.30.41.30.31.10.40.90.5-0.20.70.20.21.0
Fe content in liver0.10.10.4-0.2-0.6-0.3-0.4-0.20.1-0.5-0.2-0.2-0.5
K content in liver0.30.30.80.50.90.70.70.20.10.30.50.50.7
Mg content in liver0.50.51.30.61.20.80.90.20.20.40.50.60.9
Mn content in liver1.92.25.12.01.52.30.8-0.51.20.11.82.00.9
Na content in liver1.01.01.7-0.71.2-0.51.31.2-1.01.1-0.7-0.71.3
Rb content in liver0.70.92.50.01.60.21.20.9-0.61.3-0.10.01.4
Se content in liver0.20.20.40.6-0.00.6-0.1-0.40.5-0.40.60.5-0.2
Sr content in liver0.40.41.2-0.5-1.1-0.7-0.7-0.3-0.0-0.7-0.4-0.5-0.9
Zn content in liver2.62.86.00.7-2.40.3-2.1-1.91.5-2.20.80.6-2.4