Cpne3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000006298 0.14 0.09 4.0e-09 0.08 0.07 0.08 0.08 3.4e-09 2.0e-08 5.6e-09 8.7e-09
2 BLA gene expression ENSRNOG00000006298 0.14 0.1 1.2e-03 0.01 0.04 0.01 0.02 1.0e-01 4.0e-03 1.2e-01 2.1e-02
3 BLA mRNA stability ENSRNOG00000006298 0.24 0.1 3.8e-11 0.15 0.17 0.16 0.18 1.9e-08 2.5e-09 3.9e-09 5.9e-10
4 Brain gene expression ENSRNOG00000006298 0.2 0.08 0.0e+00 0.18 0.18 0.19 0.19 6.3e-17 2.6e-16 2.6e-17 1.5e-17
5 Brain mRNA stability ENSRNOG00000006298 0.08 0.04 8.3e-07 0.04 0.05 0.04 0.04 1.4e-04 2.1e-05 1.7e-04 1.3e-04
6 NAcc mRNA stability ENSRNOG00000006298 0.1 0.05 5.0e-07 0.07 0.08 0.07 0.08 6.4e-06 1.9e-06 4.1e-06 2.0e-06
7 OFC gene expression ENSRNOG00000006298 0.22 0.12 7.3e-03 0.04 0.06 0.06 0.06 4.1e-02 1.3e-02 1.4e-02 1.8e-02
8 PL gene expression ENSRNOG00000006298 0.05 0.04 4.1e-03 0.01 0.02 0.02 0.02 2.8e-02 1.2e-02 1.1e-02 1.5e-02
9 PL mRNA stability ENSRNOG00000006298 0.16 0.08 3.6e-12 0.12 0.14 0.12 0.13 3.9e-09 2.1e-10 2.1e-09 3.5e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail1.03.210.5-0.93.2-1.91.2-1.9-1.71.01.5-1.6
BMI without tail0.10.21.40.31.20.2-0.5-0.00.00.4-0.10.2
Body weight2.611.113.8-2.83.6-3.73.1-3.7-3.62.33.6-3.4
Epididymis fat weight0.10.20.5-0.50.7-0.60.4-0.5-0.40.40.5-0.4
Glucose0.30.40.80.80.10.7-0.90.70.7-0.2-0.70.8
Heart weight0.10.20.9-0.0-1.00.3-0.1-0.1-0.0-0.50.4-0.2
Left kidney weight1.74.88.3-2.01.1-2.32.3-2.2-2.22.12.9-2.3
Right kidney weight1.43.96.8-1.51.1-2.01.9-2.2-2.21.82.6-2.2
Tail length0.00.10.8-0.3-0.10.1-0.0-0.1-0.20.90.4-0.1
Length with tail1.45.26.9-2.40.6-2.42.4-2.5-2.51.62.6-2.5
Length without tail3.98.511.1-3.01.7-3.33.1-3.1-3.11.93.3-3.2
Liver weight, left0.30.40.9-0.50.9-0.70.5-0.8-0.7-0.20.4-0.8
Liver weight, right0.50.91.4-1.20.8-0.90.9-0.8-0.80.91.1-0.9
Parametrial fat weight1.02.010.30.3-3.20.00.60.70.5-2.1-1.50.3
Retroperitoneal fat weight0.00.10.3-0.3-0.6-0.30.30.20.2-0.2-0.30.1
Intraocular pressure0.50.73.50.61.9-0.1-0.3-0.1-0.11.40.50.2
Extensor digitorum longus weight0.62.43.5-1.31.0-1.71.5-1.9-1.80.81.7-1.7
Soleus weight6.920.225.9-4.33.8-4.94.4-5.1-5.02.54.9-4.9
Tibialis anterior weight1.65.68.6-1.92.7-2.42.0-2.9-2.70.82.4-2.6
Tibia length1.54.311.7-1.43.4-1.91.3-2.1-2.01.92.0-1.8
Number of licking bursts0.40.53.1-0.1-1.80.4-0.10.40.4-0.8-0.40.3
Food consumed during 24 hour testing period2.53.04.5-1.61.6-1.71.5-1.8-1.81.92.1-1.6
Times rat made contact with spout2.32.63.5-1.71.0-1.71.6-1.7-1.71.51.9-1.7
Mean time between licks in bursts0.10.21.3-0.1-0.1-0.20.2-0.1-0.11.10.50.0
Mean num. licks in bursts1.41.65.2-0.62.3-1.10.7-1.2-1.11.41.3-1.0
Std. dev. time between licks in bursts2.02.33.1-1.41.4-1.61.4-1.5-1.61.71.7-1.4
Water consumed over 24 hours4.75.57.1-2.22.1-2.52.2-2.7-2.61.42.6-2.5
Indifference point 0 sec3.25.27.8-1.62.8-2.62.1-2.5-2.41.32.4-2.3
Indifference point AUC1.51.82.4-1.50.1-1.41.5-1.5-1.60.81.3-1.5
Indifference point function ln k0.10.20.5-0.20.3-0.70.6-0.4-0.40.50.3-0.3
Indifference point function log k0.10.20.5-0.20.3-0.70.6-0.4-0.40.50.3-0.3
Delay discounting total patch changes 0 sec4.16.79.0-1.83.0-3.02.5-2.9-2.71.52.8-2.7
Delay discounting total patch changes 12 sec4.15.49.0-1.83.0-2.62.1-2.7-2.60.72.2-2.5
Delay discounting total patch changes 18 sec4.35.78.3-2.41.5-2.72.6-2.5-2.51.62.9-2.5
Delay discounting total patch changes 24 sec1.72.23.5-1.50.8-1.61.6-1.4-1.41.51.9-1.5
Delay discounting total patch changes 6 sec3.85.78.0-2.31.6-2.82.6-2.6-2.61.62.5-2.5
Delay discounting time to switch 0 sec2.23.45.01.8-0.71.9-2.01.91.9-1.6-2.21.9
Delay discounting water rate 0 sec1.93.04.3-1.51.5-1.91.8-2.1-1.90.21.9-2.1
Delay discounting water rate 12 sec0.71.02.9-0.90.3-1.01.1-1.1-0.90.41.7-1.2
Delay discounting water rate 18 sec0.10.20.5-0.50.3-0.40.3-0.5-0.4-0.10.7-0.5
Delay discounting water rate 24 sec1.92.74.7-1.60.4-1.71.7-1.7-1.71.42.2-1.7
Delay discounting water rate 6 sec1.31.83.0-1.40.1-1.51.7-1.4-1.40.61.7-1.5
Locomotor activity0.91.55.1-0.51.4-1.20.8-0.9-1.02.31.3-0.8
Locomotor testing distance1.62.77.8-1.21.3-1.71.5-1.2-1.32.81.9-1.1
Locomotor testing rearing3.75.910.5-2.40.4-2.62.7-2.0-2.23.23.1-2.1
Light reinforcement 10.10.10.3-0.30.2-0.30.4-0.3-0.20.20.5-0.3
Light reinforcement 21.21.51.91.1-1.31.4-1.11.31.3-1.0-1.41.2
Reaction time number correct9.313.317.2-3.63.0-4.03.6-4.1-3.92.24.1-3.8
Reaction time mean minus median0.50.62.60.3-1.60.4-0.20.50.4-1.1-0.90.4
Reaction time mean minus median AUC0.20.20.90.2-0.90.20.00.10.1-1.0-0.40.0
Reaction time num false alarms0.40.61.0-0.90.1-0.90.9-1.0-1.0-0.20.3-1.0
Reaction time num false alarms AUC0.81.11.7-1.20.4-1.21.2-1.3-1.3-0.00.6-1.3
Reaction time trials correct on left9.313.317.2-3.63.0-4.03.6-4.1-3.92.24.1-3.8
Reaction time trials on left8.912.616.1-3.52.9-3.93.5-4.0-3.82.14.0-3.7
Reaction time mean3.44.77.51.8-2.62.1-1.82.22.1-1.7-2.72.2
Reaction time mean AUC2.73.55.91.6-2.21.8-1.62.01.8-1.3-2.41.9
Median of all reaction times4.15.68.42.0-2.32.4-2.22.52.4-1.7-2.92.5
Reaction time omissions1.62.24.21.0-1.81.2-1.11.21.2-2.0-2.11.2
Reaction time false alarm rate1.11.63.21.0-1.51.2-0.91.21.1-1.3-1.81.0
Reaction time premature initiation rate1.92.54.4-1.9-1.2-1.72.1-1.4-1.61.01.5-1.7
Reaction time premature initiations6.99.813.8-3.50.4-3.53.7-3.3-3.42.03.4-3.4
Std. dev. reaction times1.62.24.41.1-2.11.3-1.01.31.2-1.7-1.91.2
Reaction time trials completed8.912.616.1-3.52.9-3.93.5-4.0-3.82.14.0-3.7
Reaction time trials AUC8.812.616.1-3.52.9-3.93.6-4.0-3.82.04.0-3.8
Social response proportion0.20.31.40.31.2-0.30.0-0.2-0.20.70.4-0.1
Social responses0.50.71.81.01.40.2-0.60.50.51.30.10.7
Social time0.81.01.81.1-0.11.3-1.31.11.00.5-0.81.2
Conditioned locomotion0.50.63.3-0.5-0.2-0.50.5-0.7-0.6-1.8-0.3-0.8
Cocaine response after cond. corrected0.40.52.40.1-1.50.4-0.10.50.4-0.6-0.90.4
Cocaine response after cond. not corrected0.30.32.0-0.0-1.40.20.10.30.2-0.5-0.60.1
Cocaine response before conditioning0.10.20.60.00.8-0.2-0.0-0.1-0.10.80.5-0.2
Saline control response5.06.79.4-2.52.6-2.82.4-3.1-3.01.32.3-2.9
Condit. Reinf. active minus inactive responses0.00.00.10.0-0.30.3-0.20.20.2-0.2-0.20.2
Condit. Reinf. active-inactive response ratio0.00.00.1-0.1-0.20.0-0.0-0.1-0.1-0.2-0.2-0.0
Condit. Reinf. active responses0.00.10.10.00.10.2-0.30.20.3-0.40.10.2
Condit. Reinf. inactive responses0.10.20.7-0.40.5-0.30.3-0.2-0.10.20.9-0.2
Condit. Reinf. lever presses0.40.50.8-0.90.8-0.60.6-0.8-0.6-0.80.8-0.8
Condit. Reinf. lever reinforcers received0.00.10.1-0.0-0.10.3-0.30.30.3-0.40.00.3
Pavlov. Cond. lever latency1.72.33.31.8-1.11.6-1.51.71.6-0.6-1.71.7
Pavlov. Cond. magazine entry latency1.51.82.9-1.7-0.2-1.21.4-1.1-1.21.61.6-1.2
Pavlov. Cond. change in total contacts1.52.14.0-2.0-0.3-1.41.6-1.4-1.50.91.7-1.5
Pavlov. Cond. index score1.72.23.6-1.90.7-1.41.4-1.5-1.51.01.8-1.6
Pavlov. Cond. latency score1.72.23.4-1.80.6-1.51.5-1.5-1.51.11.8-1.6
Pavlov. Cond. lever contacts1.92.63.7-1.91.2-1.71.6-1.8-1.70.71.8-1.8
Pavlov. Cond. magazine entry number0.80.92.71.2-0.10.8-0.90.60.7-1.6-1.30.7
Pavlov. Cond. intertrial magazine entries2.83.75.32.0-1.41.9-1.71.91.9-2.3-2.21.8
Pavlov. Cond. lever-magazine prob. diff.1.82.34.0-2.00.5-1.51.5-1.6-1.61.01.9-1.6
Pavlov. Cond. response bias1.21.63.2-1.80.3-1.21.3-1.3-1.30.71.5-1.4
Conditioned reinforcement - actives0.10.10.50.70.30.3-0.40.30.3-0.0-0.10.3
Conditioned reinforcement - inactives0.00.00.00.20.1-0.00.10.20.20.20.10.1
Conditioned locomotion1.82.23.92.00.11.6-1.81.61.6-0.5-1.41.6
Intermittent access intake day 1-15 change2.42.43.1-1.51.0-1.71.6-1.7-1.81.01.6-1.7
Intermittent access intake escalation2.12.12.8-1.60.7-1.61.7-1.6-1.60.81.4-1.6
Intermittent access intake escalation 20.80.81.3-1.1-0.1-0.91.1-0.9-1.00.30.8-1.0
Intermitt. access day 1 inactive lever presses0.10.20.30.4-0.10.1-0.20.60.50.3-0.50.5
Intermitt. access day 15 inactive lever presses2.62.93.61.8-1.91.6-1.31.91.8-1.1-1.91.8
Intermitt. access escalation Index0.10.00.3-0.2-0.5-0.10.30.1-0.00.1-0.20.0
Intermittent access day 1 total infusions1.11.21.91.40.21.2-1.41.11.3-0.7-0.71.3
Intermittent access day 15 total infusions0.00.00.10.20.20.2-0.20.10.2-0.10.10.2
Intermittent access terminal intake (last 3 days)0.40.50.90.60.10.9-0.90.80.8-0.4-0.30.8
Intermittent access total infusions0.50.60.91.00.00.8-0.90.80.9-0.6-0.40.9
Intermittent access day 1 locomotion1.41.42.21.2-0.21.4-1.51.41.4-0.4-1.21.5
Intermittent access day 15 total locomotion0.20.20.50.1-0.70.3-0.10.60.50.1-0.50.6
Intermittent access total locomotion0.80.91.40.9-0.61.0-1.01.21.1-0.4-0.91.2
Intermittent access standard deviation0.70.71.60.60.11.3-1.10.91.0-0.5-0.51.0
Cocaine induced anxiety0.50.51.21.10.80.7-0.90.60.70.0-0.40.8
Post-drug Anxiety1.01.11.91.40.91.0-1.31.01.00.2-0.81.2
Baseline Anxiety0.20.21.1-0.6-1.0-0.10.30.0-0.10.1-0.2-0.0
Lifetime Intake0.70.81.31.1-0.30.9-0.81.01.0-0.8-0.61.0
Incentive Sensitization - Responses0.60.62.51.11.6-0.6-0.0-0.3-0.20.70.5-0.2
Incentive Sensitization - Breakpoint0.60.62.40.91.5-0.70.1-0.4-0.40.80.6-0.3
Progressive ratio test 1 active lever presses1.41.42.31.1-0.71.3-1.11.51.5-0.8-1.01.4
Progressive ratio test 1 breakpoint0.50.61.00.6-0.40.9-0.71.01.0-0.5-0.50.9
Progressive ratio test 1 inactive lever presses0.30.31.7-0.0-1.3-0.00.40.30.3-0.6-0.10.1
Progressive ratio test 2 active lever presses1.01.12.91.70.30.9-1.21.11.1-0.2-0.71.2
Progressive ratio test 2 breakpoint0.60.62.61.60.60.5-0.90.70.70.1-0.30.8
Progressive ratio test 2 inactive lever presses0.40.50.90.9-0.90.5-0.30.80.8-0.8-0.50.7
Total sessions with >9 infusions0.50.60.90.9-0.90.6-0.40.90.8-0.6-0.80.8
Short access day 1 total inactive lever presses0.60.71.20.9-0.30.9-0.71.01.1-0.5-0.71.1
Short access day 10 total inactive lever presses0.80.91.9-0.80.2-1.21.4-0.9-0.90.60.8-0.9
Short access day 1 total infusions1.01.01.41.1-0.90.9-0.71.21.1-0.7-1.11.2
Short access day 10 total infusions1.71.93.31.80.51.4-1.71.51.6-0.5-0.91.6
Short access total infusions1.21.32.01.4-0.51.3-1.11.21.3-0.9-0.91.3
Short access day 1 locomotion0.91.02.60.5-1.61.0-0.61.11.0-0.4-1.21.1
Short access day 10 total locomotion0.40.40.70.30.50.6-0.80.80.70.3-0.70.8
Short access total locomotion0.50.50.80.60.00.9-0.90.90.9-0.3-0.70.9
Compulsive drug intake1.01.01.5-0.70.7-1.20.9-1.2-1.21.10.7-1.0
One hour access (0.3 mA shock)0.20.30.60.20.5-0.80.5-0.6-0.60.60.5-0.4
One hour access (shock baseline)0.81.01.81.3-0.51.0-1.01.11.1-0.6-0.81.1
Number of responses in last shaping day2.93.08.61.3-2.91.4-0.91.91.6-1.0-2.01.6
Context. condit. distance diff. score1.61.93.11.3-1.11.7-1.51.71.7-0.0-0.91.6
Locomotion velocity, session 12.52.73.9-1.42.0-1.91.6-1.8-1.70.21.5-1.8
Locomotion distance, session 11.31.62.7-1.5-0.1-1.51.7-1.3-1.40.31.2-1.5
Locomotion velocity, session 20.30.41.2-0.0-0.90.5-0.40.40.4-1.1-0.80.4
Locomotion distance, session 20.00.00.2-0.1-0.50.00.10.20.10.1-0.20.1
Locomotion velocity, session 31.21.32.3-1.01.5-1.10.8-1.2-1.21.21.3-1.0
Locomotion distance, session 30.50.62.40.41.40.3-0.50.10.21.50.50.3
Stereotopy head waving bouts, day 30.20.31.0-0.5-0.7-0.40.50.1-0.11.00.1-0.0
Stereotopy head waving duration, day 30.10.10.2-0.5-0.5-0.30.40.10.00.10.1-0.0
Locomotion velocity, session 70.70.71.30.6-0.61.1-1.00.91.0-0.9-0.50.9
Locomotion distance, session 70.20.30.60.80.20.7-0.60.60.7-0.1-0.10.6
Stereotopy head waving bouts, day 70.40.50.80.7-0.90.8-0.70.80.70.4-0.40.8
Stereotopy head waving duration, day 70.10.20.3-0.4-0.2-0.30.4-0.5-0.50.10.5-0.5
Locomotion velocity, session 80.10.10.40.1-0.60.4-0.30.20.1-0.5-0.40.1
Locomotion distance, session 80.30.41.00.4-1.00.7-0.40.80.70.1-0.40.6
Degree of sensitization distance0.70.73.20.4-1.40.3-0.00.50.5-1.8-0.90.2
Degree of sensitization stereotypy0.70.71.21.0-0.71.1-1.00.90.90.2-0.50.9
Condit. Reinf. active minus inactive responses1.21.31.91.0-1.11.3-1.21.41.3-0.1-1.21.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.3-0.7-0.10.20.0-0.10.60.10.0
Condit. Reinf. active responses2.63.24.21.6-1.52.0-1.92.02.0-0.7-1.92.0
Condit. Reinf. inactive responses3.23.84.91.9-1.32.2-2.12.22.1-1.1-2.02.2
Incentive salience index mean0.91.11.70.7-1.21.2-1.11.21.1-0.4-1.31.2
Condit. Reinf. lever presses0.50.61.40.5-0.60.9-0.90.50.6-1.2-1.10.6
Time in familiar zone, hab. session 10.50.50.70.90.80.6-0.80.70.70.80.10.8
Time in novel zone, hab. session 10.30.30.5-0.50.2-0.50.5-0.6-0.6-0.50.1-0.7
Total zone transitions, hab. session 10.30.40.7-0.80.1-0.80.8-0.5-0.60.40.4-0.6
Total locomotion distance, hab. session 10.30.40.80.5-0.70.5-0.40.90.80.2-0.80.8
Locomotion velocity, hab. session 10.20.30.70.3-0.80.3-0.20.60.5-0.0-0.80.5
Time in familiar zone, hab. session 20.50.51.90.70.50.4-0.50.60.51.40.50.8
Time in novel zone, hab. session 20.50.50.9-0.70.5-0.60.6-0.9-0.8-0.90.0-1.0
Total zone transitions, hab. session 20.10.10.2-0.40.4-0.40.4-0.4-0.4-0.00.3-0.4
Total locomotion distance, hab. session 20.50.71.00.8-0.20.8-0.90.90.9-0.4-1.01.0
Locomotion velocity, hab. session 20.40.61.10.7-0.30.8-0.80.80.8-0.6-1.00.9
Novel to familiar place preference ratio0.80.81.4-1.1-0.1-1.11.1-1.1-1.1-0.10.4-1.2
Novelty place preference0.90.91.5-1.2-0.0-1.11.2-1.1-1.1-0.10.6-1.2
Time in novel zone, NPP test1.41.42.2-1.40.2-1.41.4-1.4-1.40.20.9-1.5
Total zone transitions, NPP test0.10.10.2-0.30.3-0.30.4-0.3-0.30.50.3-0.3
Total locomotion distance, NPP test0.00.00.10.00.10.0-0.00.20.20.2-0.20.2
Locomotion velocity, NPP test0.20.30.60.4-0.40.5-0.50.70.6-0.2-0.80.7
Pavlov. Cond. lever latency1.01.31.91.0-1.41.2-0.91.41.3-0.4-1.01.2
Pavlov. Cond. magazine entry latency0.20.30.7-0.20.4-0.30.2-0.8-0.7-0.80.0-0.7
Pavlov. Cond. change in total contacts0.10.20.7-0.30.8-0.2-0.0-0.4-0.40.20.3-0.3
Pavlov. Cond. index score0.40.51.1-0.51.0-0.70.5-1.0-0.90.10.6-0.8
Pavlov. Cond. latency score0.81.01.8-0.81.2-1.00.8-1.3-1.20.20.8-1.1
Pavlov. Cond. lever contacts1.21.52.1-1.11.4-1.21.0-1.4-1.40.71.3-1.3
Pavlov. Cond. magazine entry number0.10.10.40.20.00.1-0.10.50.40.6-0.00.4
Pavlov. Cond. intertrial magazine entries0.20.20.40.50.10.5-0.60.60.6-0.2-0.30.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.1-0.61.1-0.70.5-1.1-1.00.10.7-0.9
Pavlov. Cond. response bias0.20.20.5-0.20.7-0.30.2-0.7-0.6-0.20.3-0.5
Bone: apparent density0.61.06.1-0.32.5-0.60.1-0.9-0.70.60.5-0.6
Bone surface1.32.26.7-1.12.6-1.40.8-1.7-1.61.01.1-1.4
Bone volume0.81.34.7-0.92.2-1.00.6-1.3-1.20.50.8-1.1
Bone: connectivity density0.40.73.7-0.31.9-0.70.2-0.9-0.8-0.2-0.0-0.6
Bone: cortical apparent density0.20.31.80.01.3-0.30.2-0.4-0.2-0.10.3-0.3
Bone: cortical area0.10.10.9-0.20.9-0.2-0.1-0.4-0.30.20.1-0.2
Bone: cortical porosity1.11.22.9-1.1-1.7-1.21.6-0.8-0.9-0.50.6-1.0
Bone: cortical porosity0.90.92.0-1.0-1.0-1.21.4-0.8-0.9-0.20.6-1.0
Bone: cortical thickness0.81.32.40.9-0.71.1-1.21.11.1-1.2-1.51.1
Bone: cortical thickness0.50.62.10.70.10.4-0.60.50.6-1.4-1.10.5
Bone: cortical tissue density0.20.21.70.11.3-0.30.1-0.3-0.2-0.10.3-0.3
Bone: elastic displacement0.70.73.80.1-2.00.7-0.30.70.6-0.8-0.70.6
Bone: elastic work0.10.21.0-0.5-1.0-0.00.30.1-0.00.00.3-0.1
Bone: endosteal estimation2.96.313.5-1.63.5-2.01.4-2.1-2.03.73.3-1.8
Bone: endosteal perimeter2.04.26.6-1.81.9-1.91.6-2.1-2.02.32.6-1.9
Bone: final force1.22.04.1-1.02.0-1.20.8-1.2-1.22.01.8-1.0
Bone: final moment1.42.34.9-1.02.2-1.30.8-1.3-1.32.21.9-1.0
Bone: marrow area2.96.213.4-1.53.6-2.01.4-2.1-2.03.73.3-1.7
Bone: maximum diameter0.30.62.4-0.31.5-0.50.1-0.6-0.60.90.7-0.4
Bone: maximum force1.01.75.3-0.52.3-0.90.3-0.9-0.92.31.5-0.6
Bone: maximum moment1.22.06.3-0.52.5-0.90.3-0.9-0.92.51.6-0.6
Bone: minimum diameter0.61.23.3-0.51.8-0.70.3-0.8-0.71.71.4-0.6
Bone: periosteal estimation1.83.79.8-1.13.1-1.50.9-1.6-1.52.72.4-1.3
Bone: periosteal perimeter1.62.73.4-1.61.7-1.71.3-1.8-1.81.21.8-1.6
Bone: post-yield work1.41.86.4-0.12.5-1.00.4-0.8-0.82.41.3-0.5
Bone: stiffness1.11.86.7-0.42.6-1.20.6-1.2-1.11.51.3-1.0
Bone: tissue strength0.70.71.9-1.00.1-0.70.7-0.6-0.71.41.1-0.7
Bone: trabecular number1.72.64.5-1.42.1-1.71.4-1.8-1.70.81.5-1.6
Bone: trabecular spacing0.40.52.2-0.8-1.5-0.40.7-0.3-0.4-1.0-0.1-0.6
Bone: trabecular thickness1.01.22.21.21.31.2-1.50.81.0-0.8-0.91.0
Bone: trabecular tissue density0.00.00.10.20.30.2-0.20.20.20.1-0.10.2
Breakpoint value in progressive ratio session0.30.30.60.8-0.20.7-0.40.60.6-0.1-0.50.7
Distance traveled before self-admin0.30.30.6-0.50.8-0.50.3-0.5-0.50.20.6-0.6
Distance traveled after self-admin0.10.10.30.3-0.20.2-0.40.20.2-0.50.10.1
Delta time in closed arm before/after self-admin0.30.30.40.5-0.60.6-0.50.70.6-0.5-0.50.6
Delta time in open arm before/after self-admin2.01.93.3-1.60.4-1.81.5-1.5-1.50.41.3-1.5
Diff in mean of infusions in LGA sessions0.30.31.20.71.10.4-0.60.10.20.5-0.00.3
Extinction: sum of active levers before priming0.40.41.3-0.21.1-0.60.4-0.7-0.60.60.6-0.4
Active lever presses in extinction session 60.10.10.30.30.20.6-0.20.40.5-0.40.10.4
Delta distance traveled before/after self-admin0.80.91.41.1-0.81.0-1.20.91.0-0.7-0.81.0
Delta ambulatory time before/after self-admin0.50.51.11.0-0.20.8-1.10.60.7-0.4-0.50.8
Time in closed arm before self-admin0.10.10.4-0.40.60.0-0.3-0.3-0.30.60.3-0.2
Time in closed arm after self-admin0.10.10.50.00.70.1-0.5-0.1-0.10.40.2-0.1
Time in open arm before self-admin0.10.10.4-0.0-0.60.10.40.00.0-0.30.1-0.0
Time in open arm after self-admin1.41.63.2-1.5-0.6-1.51.8-1.2-1.2-0.11.1-1.3
Sum of active levers in priming session hrs 5-60.60.61.21.10.10.8-0.60.91.0-0.5-0.51.0
Time to tail flick, vehicle, before self-admin0.10.10.2-0.40.5-0.20.3-0.3-0.30.20.3-0.3
Time to tail flick, vehicle, after self-admin0.40.50.70.80.40.8-0.60.80.8-0.3-0.40.8
Time to tail flick, test, before self-admin1.11.01.7-1.2-0.1-1.31.3-1.1-1.20.80.7-1.0
Time to tail flick, test, after self-admin0.50.50.7-0.80.3-0.80.9-0.7-0.80.70.4-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.30.5-0.50.6-0.20.50.5-0.3-0.30.6
Delta time to tail flick, test, before/after SA0.10.10.2-0.40.2-0.30.4-0.4-0.50.30.2-0.4
Ambulatory time before self-admin0.10.10.2-0.30.3-0.30.4-0.2-0.2-0.10.5-0.4
Ambulatory time after self-admin0.30.30.50.6-0.40.6-0.70.60.6-0.5-0.30.6
Total heroin consumption0.10.20.3-0.6-0.2-0.20.5-0.4-0.40.30.5-0.3
Area under the delay curve1.81.92.91.3-1.21.7-1.61.51.4-0.5-1.51.4
Delay disc. indifference point, 0s delay0.10.10.2-0.20.20.1-0.0-0.2-0.20.50.4-0.3
Delay disc. indifference point, 16s delay1.21.22.01.0-1.41.2-1.21.11.0-0.7-1.21.0
Delay disc. indifference point, 2s delay0.80.91.30.9-0.91.1-1.01.00.9-0.4-1.10.9
Delay disc. indifference point, 24s delay3.13.04.61.8-1.22.2-2.11.71.7-1.0-1.91.7
Delay disc. indifference point, 4s delay0.30.30.80.60.30.8-0.90.40.50.1-0.20.4
Delay disc. indifference point, 8s delay2.12.23.51.6-0.71.9-1.81.61.6-0.7-1.51.5
Delay discount exponential model param1.71.82.9-1.31.0-1.71.6-1.5-1.40.51.5-1.4
Delay discount hyperbolic model param1.41.52.5-1.20.8-1.61.5-1.3-1.20.41.3-1.2
Fecal boli incidents, locomotor time 14.04.36.1-2.30.8-2.52.4-2.3-2.31.02.1-2.3
Change in fecal boli incidents, locomotor task5.95.67.72.8-0.82.5-2.52.72.7-0.9-2.32.8
Time >=10cm from walls, locomotor time 12.22.23.21.8-0.31.7-1.71.61.6-0.8-1.41.6
Bouts of movement, locomotor time 11.11.21.7-1.11.0-1.01.0-1.3-1.30.81.1-1.3
Total resting periods, locomotor time 11.71.92.6-1.31.3-1.31.3-1.6-1.61.01.4-1.6
Rest time, locomotor task time 11.21.32.1-0.81.4-1.21.0-1.2-1.10.61.3-1.2
Distance moved, locomotor task time 10.70.81.70.4-1.31.1-0.70.90.8-0.6-1.10.9
Vertical activity count, locomotor time 11.71.82.71.0-1.61.6-1.31.41.3-0.6-1.51.4
Time >=10cm from walls, locomotor time 21.61.73.92.00.31.1-1.51.31.3-0.4-1.71.4
Bouts of movement, locomotor time 20.70.71.51.10.71.1-1.20.70.8-0.1-0.60.8
Total resting periods, locomotor time 20.30.41.00.61.00.8-0.90.30.40.1-0.10.4
Rest time, locomotor task time 20.91.01.8-0.91.1-1.00.9-0.9-0.91.21.3-0.9
Distance moved, locomotor task time 20.50.61.60.1-1.30.8-0.40.60.5-0.9-1.00.5
Vertical activity count, locomotor time 21.41.52.41.0-1.11.5-1.31.31.2-0.7-1.61.2
Weight adjusted by age0.30.42.60.51.6-0.1-0.3-0.1-0.10.60.10.1
Seeking ratio, delayed vs. immediate footshock0.30.41.0-1.0-0.7-0.50.8-0.4-0.50.60.3-0.4
Locomotion in novel chamber1.51.82.6-1.11.6-1.51.2-1.5-1.51.31.2-1.3
Locomotion in novel chamber post-restriction0.20.20.4-0.2-0.1-0.70.6-0.4-0.50.60.3-0.4
Progressive ratio0.20.20.70.00.3-0.70.6-0.2-0.30.80.1-0.2
Food seeking constrained by brief footshock0.20.20.80.3-0.90.2-0.00.50.4-0.4-0.50.4
Seeking ratio, punishment vs. effort0.60.71.20.4-1.01.1-0.90.80.8-1.1-0.70.6
Run reversals in cocaine runway, females0.40.41.00.4-1.00.9-0.80.60.5-0.4-0.40.6
Run reversals in cocaine runway, males0.00.00.10.30.10.0-0.10.20.20.0-0.10.3
Latency to leave start box in cocaine runway0.10.10.5-0.40.2-0.30.1-0.3-0.40.70.3-0.3
Latency to leave start box in cocaine runway, F0.30.31.2-0.21.1-0.5-0.0-0.3-0.41.00.3-0.3
Latency to leave start box in cocaine runway, M0.40.42.9-0.2-1.70.20.20.30.3-0.7-0.30.2
Cd content in liver0.30.31.9-0.00.5-0.30.3-0.6-0.4-1.4-0.1-0.5
Co content in liver9.811.518.4-2.93.3-3.53.0-3.1-3.14.14.3-3.0
Cu content in liver0.60.72.6-0.8-1.0-0.30.6-0.7-0.6-1.60.1-0.9
Fe content in liver0.30.40.7-0.6-0.2-0.60.6-0.6-0.60.80.8-0.7
K content in liver0.20.21.1-0.0-0.20.0-0.2-0.1-0.1-1.1-0.6-0.2
Mg content in liver0.30.30.6-0.50.8-0.50.2-0.8-0.7-0.10.3-0.8
Mn content in liver0.60.63.0-0.6-1.2-0.30.5-0.4-0.4-1.7-0.2-0.7
Na content in liver0.50.61.1-1.1-0.4-0.70.5-0.8-0.8-0.80.1-1.0
Rb content in liver0.91.12.2-0.81.1-0.90.7-1.0-1.01.51.3-1.0
Se content in liver0.50.61.50.6-0.11.0-0.80.60.7-1.2-0.80.6
Sr content in liver0.30.31.1-0.3-1.0-0.20.20.10.1-1.0-0.6-0.0
Zn content in liver1.61.82.9-1.11.3-1.71.1-1.4-1.31.51.3-1.3