Mettl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000008140 0.03 0.02 9.9e-03 -0 -0 -0 -0 7.6e-01 8.1e-01 4.2e-01 4.1e-01
2 Adipose gene expression ENSRNOG00000006131 0.44 0.11 0.0e+00 0.31 0.35 0.35 0.34 2.6e-35 9.8e-41 1.9e-40 1.4e-39
3 Adipose mRNA stability ENSRNOG00000006131 0.27 0.09 0.0e+00 0.19 0.23 0.23 0.23 9.6e-21 5.5e-25 2.7e-25 8.0e-25
4 BLA gene expression ENSRNOG00000006131 0.66 0.11 0.0e+00 0.42 0.42 0.45 0.44 3.5e-24 1.3e-24 2.5e-26 5.8e-26
5 Brain alternative polyA ENSRNOT00000008140 0.03 0.02 9.0e-03 0 0.02 0.01 0 2.1e-01 7.7e-03 6.1e-02 1.4e-01
6 Brain gene expression ENSRNOG00000006131 0.6 0.11 0.0e+00 0.54 0.51 0.52 0.54 3.0e-58 1.7e-54 5.6e-56 3.8e-58
7 Brain intron excision ratio chr10:90102658:90106445 0.18 0.07 8.9e-16 0.17 0.17 0.18 0.17 3.4e-15 2.4e-15 2.2e-16 2.9e-15
8 Brain mRNA stability ENSRNOG00000006131 0.18 0.07 1.3e-15 0.15 0.15 0.16 0.15 1.4e-13 4.3e-14 7.8e-15 9.9e-14
9 Eye gene expression ENSRNOG00000006131 0.48 0.16 1.8e-03 0.23 0.16 0.07 0.18 1.8e-04 1.9e-03 3.1e-02 1.1e-03
10 IL gene expression ENSRNOG00000006131 0.77 0.09 6.3e-15 0.4 0.36 0.36 0.37 1.3e-10 1.1e-09 1.5e-09 9.1e-10
11 IL mRNA stability ENSRNOG00000006131 0.26 0.13 2.2e-03 0.05 0.06 -0.01 0.03 2.8e-02 1.9e-02 9.5e-01 7.6e-02
12 LHb gene expression ENSRNOG00000006131 0.76 0.1 1.1e-11 0.25 0.36 0.32 0.33 1.4e-06 2.0e-09 1.9e-08 1.4e-08
13 LHb mRNA stability ENSRNOG00000006131 0.29 0.12 6.3e-04 0.12 0.15 0.14 0.2 9.5e-04 2.1e-04 3.5e-04 1.5e-05
14 Liver gene expression ENSRNOG00000006131 0.44 0.11 0.0e+00 0.34 0.38 0.38 0.38 1.2e-38 5.5e-45 2.6e-44 5.7e-45
15 Liver mRNA stability ENSRNOG00000006131 0.05 0.04 1.0e-03 -0 0.02 0.01 0.01 7.2e-01 6.1e-03 2.5e-02 7.0e-02
16 NAcc gene expression ENSRNOG00000006131 0.72 0.1 0.0e+00 0.45 0.54 0.55 0.54 5.2e-37 1.6e-46 8.5e-49 1.2e-47
17 NAcc mRNA stability ENSRNOG00000006131 0.11 0.06 1.8e-05 0.06 0.06 0.04 0.04 5.0e-05 5.4e-05 7.6e-04 4.1e-04
18 OFC gene expression ENSRNOG00000006131 0.74 0.09 5.3e-14 0.42 0.31 0.36 0.38 4.3e-11 4.7e-08 2.6e-09 4.4e-10
19 PL gene expression ENSRNOG00000006131 0.75 0.08 0.0e+00 0.53 0.55 0.59 0.59 5.1e-47 2.0e-49 1.4e-54 6.4e-55
20 PL intron excision ratio chr10:90102658:90106445 0.07 0.04 6.0e-04 0.05 0.03 0.03 0.03 2.0e-04 3.7e-03 2.9e-03 3.4e-03
21 PL mRNA stability ENSRNOG00000006131 0.22 0.08 1.6e-14 0.17 0.17 0.18 0.18 8.1e-13 4.3e-13 2.1e-13 9.8e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
BMI with tail3.110.023.84.03.82.53.04.23.32.10.53.13.40.74.02.03.44.93.23.13.13.33.50.3
BMI without tail3.67.413.42.72.92.33.11.82.82.01.62.82.92.03.72.53.13.03.22.82.93.22.82.1
Body weight4.519.124.04.34.54.44.93.14.63.73.14.54.73.84.84.64.84.54.84.54.54.84.83.4
Epididymis fat weight2.14.98.21.82.12.52.71.02.11.72.11.92.22.42.92.42.62.32.51.91.92.52.32.1
Glucose0.10.20.70.50.2-0.40.00.80.20.3-0.50.60.4-0.60.1-0.1-0.00.50.20.60.60.10.4-0.8
Heart weight1.62.34.41.91.61.41.51.91.71.20.41.61.80.71.71.31.52.11.41.61.71.61.70.3
Left kidney weight0.20.52.21.20.60.30.41.50.8-0.1-0.60.30.9-0.20.50.30.41.40.30.30.30.60.6-0.9
Right kidney weight0.00.10.60.6-0.00.00.10.80.4-0.2-0.5-0.10.4-0.0-0.10.2-0.10.6-0.0-0.1-0.00.20.1-0.6
Tail length1.23.711.20.61.12.02.3-1.01.61.52.71.51.63.11.72.81.90.22.11.51.52.01.53.3
Length with tail1.45.112.51.21.42.52.6-0.32.22.02.82.12.13.51.73.22.10.62.32.12.12.32.13.3
Length without tail0.20.41.40.30.31.00.60.20.50.50.80.50.51.2-0.01.10.50.20.30.50.50.40.70.7
Liver weight, left0.40.63.0-1.2-0.80.2-0.0-1.7-0.5-0.21.0-0.4-0.61.1-0.50.5-0.3-1.3-0.2-0.4-0.4-0.3-0.51.3
Liver weight, right1.11.93.0-1.5-1.7-1.7-1.5-1.0-1.5-1.7-1.3-1.1-1.5-0.8-1.1-1.4-1.4-1.0-1.5-1.1-1.1-1.4-1.6-1.2
Parametrial fat weight0.30.52.7-0.0-0.20.30.8-0.80.70.20.90.30.71.60.40.90.4-0.30.70.30.20.80.41.5
Retroperitoneal fat weight0.82.85.50.91.21.92.0-0.01.51.42.01.41.62.31.72.01.80.91.91.41.41.91.62.3
Intraocular pressure3.44.77.52.12.12.12.21.52.21.81.52.32.31.82.71.92.42.42.42.32.22.52.51.6
Extensor digitorum longus weight0.62.510.01.82.00.91.32.11.10.7-0.21.31.2-1.03.00.31.83.21.51.31.31.51.3-0.5
Soleus weight0.82.33.61.91.61.11.41.71.91.50.61.71.80.81.31.31.41.61.51.71.71.71.80.7
Tibialis anterior weight1.34.69.22.02.42.22.41.42.11.81.62.02.11.23.02.02.62.62.42.02.02.42.11.6
Tibia length0.00.10.50.50.1-0.20.10.70.3-0.1-0.50.10.50.00.0-0.10.00.50.10.10.10.20.4-0.5
Number of licking bursts0.30.30.70.90.70.80.50.80.80.50.30.40.50.30.20.60.50.70.40.40.40.50.60.2
Food consumed during 24 hour testing period4.25.17.22.02.32.72.61.02.31.82.02.12.22.32.62.62.62.02.52.12.12.52.22.3
Times rat made contact with spout0.60.61.00.90.80.90.90.61.00.50.40.90.80.70.60.80.80.60.80.90.90.90.80.8
Mean time between licks in bursts1.82.65.02.11.81.31.42.01.81.40.51.71.80.61.81.11.72.21.61.71.71.71.70.4
Mean num. licks in bursts0.10.10.3-0.2-0.0-0.00.3-0.4-0.0-0.10.10.30.10.30.50.10.2-0.00.40.30.30.20.10.4
Std. dev. time between licks in bursts0.10.10.30.50.40.20.10.40.30.40.20.20.2-0.10.50.00.40.60.20.20.20.30.2-0.0
Water consumed over 24 hours0.00.10.20.30.20.40.20.10.3-0.3-0.00.00.10.40.20.20.30.30.10.00.00.30.10.2
Indifference point 0 sec0.81.35.1-0.20.41.11.2-1.20.50.61.80.80.52.01.01.51.1-0.21.10.80.91.00.62.3
Indifference point AUC1.01.22.40.71.11.21.20.11.00.61.00.90.91.11.41.51.30.81.20.90.81.31.11.4
Indifference point function ln k0.50.71.3-0.9-1.1-0.6-0.8-0.8-0.8-0.7-0.4-0.9-0.7-0.1-1.0-0.8-0.9-0.9-0.9-0.9-0.9-0.8-1.1-0.5
Indifference point function log k0.50.71.3-0.9-1.1-0.6-0.8-0.8-0.8-0.7-0.4-0.9-0.7-0.1-1.0-0.8-0.9-0.9-0.9-0.9-0.9-0.8-1.1-0.5
Delay discounting total patch changes 0 sec1.11.85.80.20.61.41.5-0.90.90.91.91.10.82.31.21.81.30.11.41.11.11.31.02.4
Delay discounting total patch changes 12 sec0.91.15.7-0.30.51.11.1-1.30.40.61.70.50.41.71.01.51.0-0.51.10.50.50.90.52.4
Delay discounting total patch changes 18 sec1.92.53.31.51.61.51.80.91.81.51.31.61.71.51.41.81.61.11.71.61.61.81.81.7
Delay discounting total patch changes 24 sec1.01.34.40.10.51.11.3-0.90.80.71.70.70.72.01.01.81.1-0.01.20.70.71.21.02.1
Delay discounting total patch changes 6 sec0.81.23.10.50.71.21.3-0.31.00.71.31.00.81.71.01.71.10.31.21.01.11.21.11.8
Delay discounting time to switch 0 sec0.10.10.5-0.1-0.2-0.2-0.40.2-0.30.0-0.3-0.4-0.2-0.5-0.7-0.5-0.5-0.3-0.4-0.4-0.4-0.5-0.1-0.4
Delay discounting water rate 0 sec0.81.22.30.70.81.11.20.11.10.71.01.30.91.51.31.41.30.91.21.31.31.21.01.3
Delay discounting water rate 12 sec0.20.42.00.2-0.5-0.6-0.50.9-0.1-0.5-1.10.1-0.2-0.7-0.5-0.6-0.50.5-0.70.10.2-0.4-0.3-1.4
Delay discounting water rate 18 sec1.01.32.3-1.4-1.5-1.3-1.3-1.0-1.3-1.1-0.7-0.9-1.3-0.4-1.4-1.0-1.3-1.3-1.3-0.9-0.9-1.4-1.3-0.7
Delay discounting water rate 24 sec0.20.30.9-0.2-0.4-1.0-0.60.2-0.4-0.2-0.70.1-0.3-0.7-0.6-0.7-0.6-0.3-0.50.10.1-0.6-0.3-0.7
Delay discounting water rate 6 sec0.10.10.3-0.2-0.5-0.3-0.3-0.2-0.1-0.5-0.2-0.4-0.20.2-0.3-0.2-0.3-0.0-0.4-0.4-0.4-0.2-0.4-0.3
Locomotor activity0.10.10.4-0.20.10.20.0-0.5-0.00.50.60.2-0.00.3-0.10.20.1-0.50.20.20.3-0.0-0.20.6
Locomotor testing distance0.60.92.40.30.70.90.9-0.40.81.31.61.00.81.30.61.10.8-0.21.11.01.00.90.61.6
Locomotor testing rearing0.40.71.90.81.00.60.70.50.91.40.91.00.90.40.30.60.60.01.01.00.90.80.81.0
Light reinforcement 10.51.06.0-1.6-1.0-0.10.1-2.4-0.8-0.71.0-1.0-0.71.10.40.2-0.1-1.20.1-1.0-1.0-0.0-0.61.5
Light reinforcement 20.91.26.3-1.8-1.4-0.5-0.4-2.5-1.1-0.90.7-1.2-1.11.0-0.2-0.1-0.5-1.5-0.4-1.2-1.1-0.5-0.81.1
Reaction time number correct0.10.10.60.2-0.1-0.20.00.5-0.0-0.2-0.4-0.00.1-0.30.2-0.2-0.00.6-0.1-0.00.0-0.0-0.1-0.7
Reaction time mean minus median0.20.30.6-0.5-0.5-0.4-0.5-0.2-0.7-0.8-0.6-0.2-0.7-0.5-0.5-0.7-0.5-0.3-0.7-0.2-0.3-0.7-0.5-0.7
Reaction time mean minus median AUC1.92.43.6-1.6-1.6-1.5-1.6-1.0-1.9-1.8-1.4-1.2-1.9-1.4-1.4-1.8-1.5-1.2-1.8-1.2-1.2-1.8-1.7-1.4
Reaction time num false alarms2.63.65.91.71.82.31.91.22.01.91.82.11.92.21.42.41.91.31.92.12.11.91.82.0
Reaction time num false alarms AUC1.92.75.01.21.42.11.60.61.71.61.81.81.52.21.22.21.70.91.61.81.81.61.42.1
Reaction time trials correct on left0.10.10.60.2-0.1-0.20.00.5-0.0-0.2-0.4-0.00.1-0.30.2-0.2-0.00.6-0.1-0.00.0-0.0-0.1-0.7
Reaction time trials on left0.10.10.50.2-0.2-0.20.10.5-0.0-0.2-0.4-0.00.1-0.30.2-0.2-0.00.6-0.1-0.00.0-0.0-0.1-0.7
Reaction time mean2.43.34.5-1.9-2.0-1.8-1.9-1.5-2.0-1.7-1.2-1.8-2.1-1.3-2.1-1.7-2.0-2.0-2.1-1.8-1.8-2.0-1.8-1.3
Reaction time mean AUC3.03.95.4-2.1-2.1-2.0-2.0-1.7-2.2-1.8-1.3-2.0-2.3-1.5-2.3-1.9-2.2-2.2-2.3-2.0-2.0-2.2-1.9-1.4
Median of all reaction times2.73.75.1-2.1-2.1-1.8-2.0-1.7-2.1-1.7-1.1-2.0-2.2-1.3-2.3-1.7-2.1-2.2-2.2-2.0-2.0-2.1-1.9-1.2
Reaction time omissions0.40.61.7-1.0-1.3-0.8-0.4-1.2-0.7-1.0-0.3-0.6-0.80.3-0.9-0.4-0.9-1.1-0.8-0.6-0.7-0.6-0.50.0
Reaction time false alarm rate1.52.24.21.11.31.91.30.51.51.61.71.61.32.00.82.01.40.51.41.61.61.41.22.0
Reaction time premature initiation rate0.60.91.90.50.71.11.2-0.10.80.40.80.80.81.31.21.41.10.61.00.80.71.00.61.3
Reaction time premature initiations0.50.71.60.50.60.91.20.10.80.20.60.70.81.11.31.21.00.91.00.70.71.00.61.0
Std. dev. reaction times1.52.03.2-1.7-1.6-1.3-1.5-1.3-1.8-1.4-0.9-1.1-1.8-0.9-1.5-1.4-1.4-1.4-1.7-1.1-1.2-1.7-1.5-0.9
Reaction time trials completed0.10.10.50.2-0.2-0.20.10.5-0.0-0.2-0.4-0.00.1-0.30.2-0.2-0.00.6-0.1-0.00.0-0.0-0.1-0.7
Reaction time trials AUC0.10.10.60.1-0.2-0.20.00.4-0.1-0.3-0.4-0.1-0.0-0.40.2-0.3-0.10.6-0.1-0.1-0.1-0.1-0.1-0.8
Social response proportion0.80.92.71.21.00.50.31.60.80.8-0.21.40.7-0.20.90.30.81.60.41.41.50.50.7-0.6
Social responses0.20.20.70.30.50.40.20.40.30.40.20.90.20.20.40.50.50.50.20.90.80.20.30.2
Social time1.21.64.21.51.40.90.72.01.11.1-0.02.01.10.20.90.81.11.70.72.02.10.81.1-0.2
Conditioned locomotion0.00.00.2-0.30.10.10.2-0.4-0.3-0.30.2-0.0-0.20.00.2-0.00.1-0.1-0.0-0.0-0.0-0.1-0.30.4
Cocaine response after cond. corrected0.50.62.71.20.50.00.51.60.90.2-0.81.00.9-0.20.20.00.31.20.31.01.00.50.8-0.8
Cocaine response after cond. not corrected0.30.41.50.6-0.2-0.6-0.31.20.3-0.0-1.10.50.3-0.5-0.9-0.4-0.60.2-0.40.50.5-0.20.3-1.2
Cocaine response before conditioning1.21.43.3-1.4-1.4-1.0-1.3-1.3-1.2-0.7-0.3-1.1-1.2-0.3-1.8-0.7-1.4-1.8-1.3-1.1-1.1-1.3-1.2-0.3
Saline control response0.91.22.40.81.31.31.20.21.01.21.30.91.11.01.31.21.30.61.40.90.91.21.11.5
Condit. Reinf. active minus inactive responses0.91.14.20.20.30.90.8-0.50.81.31.50.91.02.0-0.11.40.5-0.70.90.90.90.71.02.0
Condit. Reinf. active-inactive response ratio0.60.62.40.20.30.70.5-0.10.61.11.10.60.91.5-0.31.10.3-0.60.70.60.60.50.81.4
Condit. Reinf. active responses1.41.97.50.00.51.31.3-1.00.91.52.21.11.12.60.42.00.9-0.71.41.11.11.11.12.7
Condit. Reinf. inactive responses0.70.94.0-0.7-0.10.70.9-1.60.10.41.60.20.21.60.61.20.6-0.70.80.20.20.60.12.0
Condit. Reinf. lever presses0.30.41.90.00.20.40.6-0.40.50.70.90.60.51.2-0.10.90.3-0.60.60.60.60.40.51.4
Condit. Reinf. lever reinforcers received1.11.66.10.10.41.11.1-0.80.91.41.91.01.02.40.31.80.8-0.61.21.01.01.01.02.5
Pavlov. Cond. lever latency0.10.10.50.00.0-0.2-0.30.3-0.3-0.3-0.5-0.2-0.2-0.50.2-0.4-0.00.5-0.2-0.2-0.2-0.2-0.1-0.7
Pavlov. Cond. magazine entry latency0.40.41.2-0.2-0.5-0.6-0.70.2-0.5-0.4-0.7-0.5-0.6-1.1-0.7-0.7-0.7-0.3-0.8-0.5-0.5-0.7-0.6-1.1
Pavlov. Cond. change in total contacts0.10.20.9-0.20.20.50.5-0.60.10.40.80.1-0.00.50.00.60.2-0.50.30.10.10.2-0.00.9
Pavlov. Cond. index score0.00.00.20.20.10.10.10.10.30.40.20.20.20.1-0.30.3-0.0-0.20.10.20.20.10.20.1
Pavlov. Cond. latency score0.00.00.20.20.00.10.00.20.30.40.10.20.20.0-0.40.2-0.1-0.20.00.20.20.00.20.0
Pavlov. Cond. lever contacts0.10.10.4-0.3-0.20.10.2-0.50.00.10.4-0.0-0.00.5-0.20.3-0.0-0.50.1-0.0-0.00.0-0.10.6
Pavlov. Cond. magazine entry number1.11.33.20.50.91.21.3-0.10.90.81.40.91.11.71.31.41.30.61.30.90.91.21.01.8
Pavlov. Cond. intertrial magazine entries7.09.018.81.72.33.23.2-0.02.72.63.52.92.84.32.93.93.11.43.32.92.93.22.84.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.1-0.00.10.10.10.20.30.10.10.1-0.0-0.30.2-0.1-0.2-0.00.10.10.00.10.0
Pavlov. Cond. response bias0.00.10.2-0.3-0.3-0.2-0.1-0.4-0.1-0.10.0-0.2-0.3-0.0-0.4-0.1-0.3-0.5-0.2-0.2-0.2-0.2-0.30.1
Conditioned reinforcement - actives0.80.81.30.71.11.00.90.50.80.80.91.10.60.71.10.81.10.90.91.11.10.90.70.9
Conditioned reinforcement - inactives0.50.61.70.60.80.60.70.50.70.70.51.30.60.70.70.60.80.70.61.31.30.60.60.7
Conditioned locomotion1.72.03.01.11.31.41.50.71.31.41.31.71.41.51.31.51.51.01.51.71.71.41.31.5
Intermittent access intake day 1-15 change0.90.91.91.31.00.10.81.21.31.00.01.31.20.20.50.40.50.60.91.31.31.01.40.4
Intermittent access intake escalation0.30.30.70.80.60.10.30.80.70.5-0.10.70.6-0.10.20.10.30.40.40.70.70.50.80.0
Intermittent access intake escalation 20.60.61.11.00.80.40.70.81.00.80.31.11.00.40.40.60.60.50.81.11.10.81.00.5
Intermitt. access day 1 inactive lever presses0.80.93.00.20.51.20.8-0.10.60.81.21.00.61.7-0.01.50.6-0.30.61.01.00.60.81.7
Intermitt. access day 15 inactive lever presses0.70.83.40.10.41.31.0-0.40.50.31.20.70.51.80.31.50.80.10.60.70.70.60.71.5
Intermitt. access escalation Index0.60.52.80.3-0.0-0.6-0.61.0-0.3-0.3-1.1-0.5-0.2-1.5-0.5-0.7-0.50.5-0.6-0.5-0.5-0.6-0.3-1.7
Intermittent access day 1 total infusions0.60.71.60.60.70.70.80.40.70.60.61.30.70.91.01.00.90.70.81.31.30.80.80.9
Intermittent access day 15 total infusions1.01.12.61.11.20.60.90.91.10.90.41.61.00.51.20.81.11.01.11.61.61.11.10.7
Intermittent access terminal intake (last 3 days)1.71.93.51.11.31.11.30.71.41.21.01.91.31.21.41.41.40.91.51.91.91.41.31.5
Intermittent access total infusions1.41.52.70.81.11.01.20.31.11.11.11.61.01.31.31.41.30.61.31.61.61.21.11.6
Intermittent access day 1 locomotion3.03.15.11.31.61.81.80.91.51.51.52.31.61.91.72.01.91.41.82.32.31.71.61.9
Intermittent access day 15 total locomotion2.42.54.81.01.61.51.60.51.31.31.42.21.31.71.61.81.70.91.62.22.21.41.42.0
Intermittent access total locomotion3.94.47.81.31.92.22.20.51.81.82.22.41.82.62.02.62.21.22.22.42.42.01.92.8
Intermittent access standard deviation0.40.41.30.10.1-0.10.5-0.40.60.50.51.00.60.90.30.30.2-0.40.71.01.00.70.71.1
Cocaine induced anxiety0.10.10.60.4-0.2-0.2-0.30.80.1-0.4-0.80.10.0-0.3-0.2-0.3-0.20.5-0.40.10.1-0.10.1-0.7
Post-drug Anxiety0.60.72.81.40.70.80.61.71.10.2-0.40.50.90.20.50.60.61.50.40.50.50.80.9-0.5
Baseline Anxiety0.10.10.40.50.20.30.40.40.5-0.00.0-0.30.40.00.20.40.20.60.2-0.3-0.30.40.4-0.3
Lifetime Intake1.11.33.30.50.81.11.1-0.10.90.91.31.40.81.51.11.41.10.31.21.41.41.10.91.8
Incentive Sensitization - Responses1.41.42.90.71.10.91.20.21.01.11.21.70.91.31.11.31.20.61.11.71.71.10.91.5
Incentive Sensitization - Breakpoint1.31.32.90.71.00.81.10.20.91.11.11.70.91.21.01.21.10.51.11.71.71.00.81.4
Progressive ratio test 1 active lever presses2.32.45.20.91.21.71.70.11.31.31.81.51.32.11.42.31.60.71.61.51.51.51.42.2
Progressive ratio test 1 breakpoint3.33.46.91.11.62.12.00.31.61.52.11.91.62.41.82.62.01.02.01.91.91.81.62.5
Progressive ratio test 1 inactive lever presses1.92.05.30.61.31.61.6-0.21.01.11.81.41.02.01.22.31.60.51.41.41.41.21.12.1
Progressive ratio test 2 active lever presses2.12.34.70.81.21.61.6-0.01.21.21.81.81.12.11.42.01.60.71.51.81.81.41.12.2
Progressive ratio test 2 breakpoint3.43.86.01.31.71.92.10.51.81.72.02.41.72.41.82.42.01.12.02.42.41.91.72.5
Progressive ratio test 2 inactive lever presses1.21.43.70.10.91.41.1-0.40.40.61.51.50.41.81.31.71.40.51.01.51.50.80.51.9
Total sessions with >9 infusions0.10.10.8-0.6-0.4-0.4-0.3-0.9-0.5-0.40.10.0-0.50.10.1-0.0-0.1-0.4-0.20.00.0-0.2-0.60.3
Short access day 1 total inactive lever presses0.40.41.20.70.60.40.40.90.60.70.21.10.70.40.20.30.40.50.41.11.10.40.90.3
Short access day 10 total inactive lever presses0.30.30.80.20.60.80.70.00.30.20.60.60.40.90.50.70.70.40.50.60.60.40.40.7
Short access day 1 total infusions0.30.31.0-0.00.40.50.6-0.50.20.30.80.60.20.80.70.90.60.10.60.60.60.50.31.0
Short access day 10 total infusions2.52.76.40.81.21.61.6-0.01.31.41.92.11.22.31.42.21.70.61.62.12.11.61.42.5
Short access total infusions1.01.13.50.30.71.11.0-0.30.80.91.41.20.71.60.81.61.00.01.01.21.20.90.71.9
Short access day 1 locomotion2.02.13.90.91.21.21.50.31.21.21.32.01.21.61.81.71.61.01.62.02.01.51.21.8
Short access day 10 total locomotion6.87.511.71.92.73.13.00.82.52.42.92.92.53.32.63.43.01.82.92.92.92.72.43.4
Short access total locomotion3.33.45.51.21.81.91.80.61.61.61.72.31.52.01.92.32.01.21.82.32.31.81.52.2
Compulsive drug intake0.40.41.50.1-0.5-0.8-0.60.5-0.1-0.2-0.8-0.3-0.2-0.9-0.8-1.0-0.8-0.1-0.7-0.3-0.3-0.4-0.1-1.2
One hour access (0.3 mA shock)0.80.92.10.91.10.70.80.71.01.00.61.40.90.70.70.90.90.60.91.41.40.91.00.9
One hour access (shock baseline)1.01.11.90.71.31.41.10.30.90.91.21.00.81.11.21.41.30.81.11.01.01.00.81.4
Number of responses in last shaping day3.03.05.02.01.51.62.01.52.21.61.21.82.11.61.31.81.51.51.81.81.82.02.21.2
Context. condit. distance diff. score0.30.31.30.90.90.50.51.20.50.1-0.20.50.3-0.70.60.00.51.10.30.50.50.30.3-0.5
Locomotion velocity, session 10.30.41.7-0.7-0.8-0.30.0-1.3-0.10.00.5-0.1-0.11.1-0.40.3-0.3-1.20.0-0.1-0.10.0-0.11.1
Locomotion distance, session 10.30.41.6-0.9-0.9-0.5-0.2-1.3-0.5-0.60.1-0.6-0.50.5-0.3-0.1-0.5-0.9-0.3-0.6-0.6-0.3-0.50.4
Locomotion velocity, session 20.70.84.1-1.2-1.0-0.6-0.6-1.6-0.8-0.10.4-0.7-0.60.5-1.4-0.0-0.9-2.0-0.5-0.7-0.7-0.8-0.60.8
Locomotion distance, session 20.40.51.5-0.9-0.8-0.6-0.6-1.2-0.7-0.30.1-0.9-0.6-0.0-0.8-0.2-0.7-1.2-0.5-0.9-0.9-0.6-0.70.2
Locomotion velocity, session 30.40.51.1-0.9-1.0-1.0-0.5-0.7-0.7-0.6-0.5-0.4-0.6-0.2-0.9-0.6-0.9-1.0-0.7-0.4-0.4-0.7-0.5-0.3
Locomotion distance, session 30.10.10.6-0.3-0.4-0.6-0.2-0.0-0.3-0.0-0.30.0-0.1-0.1-0.8-0.3-0.6-0.6-0.30.00.0-0.5-0.1-0.2
Stereotopy head waving bouts, day 31.51.82.7-1.6-1.6-1.5-1.2-1.4-1.6-1.5-0.9-1.2-1.5-0.7-1.2-1.3-1.4-1.4-1.4-1.2-1.2-1.4-1.4-0.7
Stereotopy head waving duration, day 30.50.61.1-1.1-1.0-0.7-0.6-1.0-1.0-1.0-0.4-0.8-1.0-0.4-0.4-0.7-0.7-0.7-0.8-0.8-0.8-0.8-1.0-0.4
Locomotion velocity, session 70.60.71.0-0.7-0.8-0.8-0.8-0.5-0.8-0.9-0.7-0.9-1.0-0.7-0.9-0.9-0.9-0.7-1.0-0.9-0.9-0.9-0.9-0.7
Locomotion distance, session 70.10.10.20.0-0.1-0.1-0.20.0-0.1-0.2-0.2-0.4-0.3-0.5-0.1-0.3-0.10.1-0.3-0.4-0.4-0.2-0.3-0.4
Stereotopy head waving bouts, day 71.72.02.8-1.5-1.5-1.3-1.6-1.0-1.6-1.2-0.9-1.3-1.6-0.9-1.6-1.4-1.5-1.5-1.6-1.3-1.3-1.7-1.5-1.0
Stereotopy head waving duration, day 73.94.86.3-2.4-2.2-1.9-2.3-1.8-2.5-1.9-1.3-2.3-2.5-1.6-2.4-2.1-2.3-2.4-2.4-2.3-2.3-2.5-2.5-1.4
Locomotion velocity, session 81.72.13.31.11.41.61.70.61.41.41.41.51.41.31.31.81.40.91.51.51.51.41.51.6
Locomotion distance, session 80.00.10.3-0.3-0.00.00.1-0.5-0.2-0.20.2-0.4-0.3-0.2-0.0-0.0-0.1-0.3-0.1-0.4-0.4-0.1-0.30.2
Degree of sensitization distance0.50.51.40.80.91.10.70.40.80.30.70.20.40.31.20.71.01.20.70.20.20.90.40.4
Degree of sensitization stereotypy1.82.03.3-1.2-1.3-1.3-1.7-0.6-1.5-1.0-1.1-1.3-1.5-1.4-1.8-1.5-1.6-1.4-1.7-1.3-1.3-1.7-1.5-1.3
Condit. Reinf. active minus inactive responses0.91.02.90.40.60.91.2-0.21.01.01.21.01.01.60.51.40.8-0.21.21.01.01.01.01.7
Condit. Reinf. active-inactive response ratio0.10.10.30.40.30.20.50.20.50.40.20.50.50.4-0.10.40.2-0.20.40.50.50.30.50.5
Condit. Reinf. active responses1.01.24.80.00.51.01.2-0.80.71.01.60.90.91.90.61.60.8-0.51.20.90.91.00.92.2
Condit. Reinf. inactive responses0.50.52.6-0.6-0.10.50.5-1.3-0.00.31.30.20.11.40.50.90.4-0.60.60.20.20.40.21.6
Incentive salience index mean0.40.52.1-0.10.10.50.6-0.60.40.60.90.40.51.4-0.21.00.3-0.80.60.40.40.40.51.4
Condit. Reinf. lever presses0.30.41.7-0.9-0.7-0.2-0.4-1.1-0.6-0.30.2-0.6-0.60.4-1.0-0.1-0.6-1.3-0.5-0.6-0.6-0.6-0.50.6
Time in familiar zone, hab. session 11.31.21.71.11.31.31.00.61.21.21.01.11.00.71.31.21.31.11.21.11.11.21.01.0
Time in novel zone, hab. session 11.01.01.9-0.7-1.1-1.3-0.9-0.1-0.9-1.1-1.2-0.9-0.8-0.9-1.1-1.2-1.2-0.6-1.1-0.9-0.9-1.1-0.8-1.4
Total zone transitions, hab. session 10.20.30.70.70.60.40.50.40.80.70.50.60.50.20.60.40.60.60.60.60.60.70.60.5
Total locomotion distance, hab. session 10.10.10.5-0.1-0.4-0.10.1-0.60.3-0.10.3-0.1-0.00.7-0.30.2-0.1-0.5-0.0-0.1-0.10.2-0.00.5
Locomotion velocity, hab. session 10.10.21.2-0.1-0.30.20.3-0.70.40.10.60.10.11.1-0.00.60.1-0.50.20.10.10.40.10.9
Time in familiar zone, hab. session 21.31.32.11.21.51.21.00.91.21.40.91.31.20.51.01.11.20.91.31.31.31.21.20.9
Time in novel zone, hab. session 21.91.93.2-1.4-1.8-1.6-1.3-1.0-1.4-1.7-1.2-1.4-1.4-0.7-1.3-1.4-1.5-1.1-1.5-1.4-1.4-1.4-1.4-1.2
Total zone transitions, hab. session 20.00.00.10.20.40.40.2-0.10.20.10.4-0.1-0.0-0.00.30.20.30.20.2-0.1-0.10.2-0.00.4
Total locomotion distance, hab. session 20.30.41.4-0.8-0.5-0.0-0.2-1.2-0.5-0.60.4-0.9-0.70.2-0.0-0.2-0.1-0.6-0.3-0.9-0.9-0.2-0.70.6
Locomotion velocity, hab. session 20.20.31.3-0.7-0.5-0.1-0.2-1.1-0.5-0.60.3-0.9-0.70.20.0-0.2-0.1-0.5-0.3-0.9-0.9-0.2-0.70.5
Novel to familiar place preference ratio0.80.81.31.11.01.01.10.91.10.40.40.91.00.80.91.01.01.20.90.90.91.01.00.5
Novelty place preference0.40.40.80.80.70.70.80.70.80.20.20.60.70.60.60.70.70.90.60.60.60.70.70.3
Time in novel zone, NPP test0.30.30.50.70.50.60.60.70.60.10.00.50.60.40.30.50.50.70.40.50.50.50.60.1
Total zone transitions, NPP test0.30.41.3-0.9-0.7-0.4-0.5-1.1-0.6-0.50.2-0.8-0.8-0.0-0.3-0.3-0.4-0.8-0.5-0.8-0.8-0.4-0.80.2
Total locomotion distance, NPP test0.40.62.0-1.1-1.0-0.4-0.6-1.4-0.7-0.60.3-0.9-0.90.4-0.7-0.3-0.6-1.1-0.6-0.9-0.9-0.6-0.90.4
Locomotion velocity, NPP test0.20.31.5-0.7-0.60.0-0.1-1.2-0.4-0.40.5-0.6-0.50.60.10.1-0.1-0.5-0.1-0.6-0.6-0.1-0.50.6
Pavlov. Cond. lever latency0.40.62.5-0.2-0.3-0.8-0.70.2-0.7-0.8-1.0-0.5-0.7-1.60.2-1.1-0.40.4-0.6-0.5-0.5-0.6-0.7-1.4
Pavlov. Cond. magazine entry latency0.70.94.0-0.4-0.00.60.8-1.10.40.81.40.60.52.0-0.21.30.3-1.00.70.60.60.50.52.0
Pavlov. Cond. change in total contacts0.80.84.1-0.30.00.80.7-1.10.50.61.40.40.41.9-0.11.30.4-1.00.60.40.40.50.42.0
Pavlov. Cond. index score0.60.83.40.00.20.70.8-0.60.60.81.30.70.71.8-0.11.20.5-0.70.70.70.70.60.71.8
Pavlov. Cond. latency score0.60.72.80.20.40.80.8-0.40.70.91.20.70.71.6-0.01.20.5-0.50.80.70.70.60.71.7
Pavlov. Cond. lever contacts0.70.82.20.60.60.90.90.10.91.01.10.81.01.50.11.20.6-0.10.90.80.80.81.01.4
Pavlov. Cond. magazine entry number0.60.73.01.00.60.0-0.41.70.3-0.0-1.00.00.1-1.60.6-0.70.21.6-0.20.00.00.10.1-1.7
Pavlov. Cond. intertrial magazine entries1.41.73.70.71.11.51.5-0.21.10.91.41.01.11.41.91.61.60.91.71.01.01.61.11.8
Pavlov. Cond. lever-magazine prob. diff.0.70.93.50.20.30.81.0-0.40.80.91.30.90.91.90.01.30.6-0.50.90.90.90.70.91.8
Pavlov. Cond. response bias0.60.73.8-0.7-0.50.20.5-1.30.10.31.10.30.21.9-0.71.0-0.1-1.50.30.30.30.20.21.8
Bone: apparent density0.50.92.7-1.2-1.3-0.8-0.8-1.6-0.7-0.70.1-0.8-0.70.9-1.2-0.3-0.9-1.6-0.7-0.8-0.8-0.7-0.70.6
Bone surface1.12.07.60.80.61.11.10.11.61.51.51.41.62.80.11.90.9-0.21.31.41.41.31.52.1
Bone volume0.71.26.20.30.10.80.8-0.51.10.91.31.01.02.50.01.50.6-0.50.91.01.01.01.01.9
Bone: connectivity density0.50.72.7-1.1-1.2-0.7-0.5-1.4-0.6-0.50.2-0.7-0.51.0-1.2-0.1-0.8-1.7-0.5-0.7-0.7-0.6-0.60.8
Bone: cortical apparent density6.48.411.7-3.2-3.1-3.0-2.8-2.7-3.4-3.1-2.0-3.2-3.3-2.4-2.0-3.2-2.7-2.4-2.9-3.2-3.2-2.9-3.4-2.1
Bone: cortical area0.81.32.81.10.70.81.20.71.40.70.41.41.41.70.71.20.90.81.01.41.41.31.41.0
Bone: cortical porosity8.18.813.63.02.42.72.62.23.63.52.23.73.63.51.13.52.31.42.83.73.72.93.62.5
Bone: cortical porosity6.87.311.52.92.32.42.52.33.33.01.73.43.32.91.23.02.11.62.63.43.42.73.41.9
Bone: cortical thickness2.23.76.8-1.3-2.0-2.5-1.9-0.5-1.7-2.5-2.6-1.7-1.7-1.8-1.6-2.6-2.0-0.8-2.2-1.7-1.7-1.8-1.7-2.4
Bone: cortical thickness3.84.46.8-1.5-2.2-2.5-2.2-0.7-1.9-2.3-2.4-2.0-2.0-1.9-2.3-2.6-2.4-1.5-2.4-2.0-2.0-2.2-2.0-2.4
Bone: cortical tissue density6.38.211.6-3.2-3.1-3.0-2.8-2.7-3.4-3.0-1.9-3.2-3.3-2.3-1.9-3.1-2.7-2.4-2.8-3.2-3.2-2.9-3.4-2.0
Bone: elastic displacement1.21.42.9-0.6-1.2-1.7-1.30.1-0.9-1.1-1.7-0.6-0.9-1.3-1.3-1.6-1.4-0.6-1.3-0.6-0.6-1.2-0.8-1.7
Bone: elastic work0.10.10.30.0-0.4-0.6-0.20.20.1-0.2-0.60.30.10.2-0.4-0.3-0.3-0.1-0.20.30.3-0.10.2-0.3
Bone: endosteal estimation7.917.127.53.43.74.44.21.84.54.54.14.54.45.12.75.23.91.94.44.54.54.24.44.8
Bone: endosteal perimeter13.026.838.04.74.95.45.42.95.75.34.55.75.75.73.96.25.03.35.45.75.75.45.75.2
Bone: final force0.10.10.40.2-0.3-0.5-0.20.20.40.1-0.40.60.30.5-0.4-0.1-0.2-0.2-0.10.60.60.10.30.1
Bone: final moment0.10.10.40.1-0.4-0.6-0.30.10.30.1-0.30.60.20.6-0.5-0.1-0.3-0.4-0.10.60.60.10.20.1
Bone: marrow area7.716.526.53.43.64.34.11.84.44.54.04.44.44.92.65.13.81.94.34.44.44.14.34.7
Bone: maximum diameter3.25.89.82.22.02.22.41.32.82.31.92.82.83.11.52.92.11.32.52.82.82.62.82.5
Bone: maximum force0.71.32.21.20.80.61.10.81.50.80.41.51.41.50.91.01.00.91.11.51.51.31.50.9
Bone: maximum moment0.71.22.31.00.60.51.00.61.40.80.41.41.31.50.71.00.80.71.01.41.41.21.40.9
Bone: minimum diameter10.218.827.43.83.84.54.62.14.84.03.84.74.65.23.55.24.32.84.54.74.74.74.74.6
Bone: periosteal estimation5.010.118.52.62.63.13.31.33.63.12.93.53.54.32.04.02.91.53.33.53.53.33.53.7
Bone: periosteal perimeter4.98.011.73.02.52.52.82.23.42.81.83.43.43.11.83.12.52.02.83.43.43.03.42.2
Bone: post-yield work4.25.88.62.82.62.42.22.52.82.31.32.62.81.81.92.42.32.42.42.62.62.52.91.3
Bone: stiffness0.20.40.60.50.60.50.70.20.70.50.50.60.70.70.50.60.60.30.70.60.60.70.70.7
Bone: tissue strength0.90.91.8-0.6-0.7-1.2-1.30.1-0.9-0.7-1.2-0.7-0.8-1.3-0.8-1.3-1.0-0.3-1.0-0.7-0.7-1.0-0.7-1.3
Bone: trabecular number0.30.51.9-0.9-0.9-0.3-0.2-1.4-0.3-0.20.6-0.5-0.21.4-0.90.3-0.4-1.4-0.2-0.5-0.5-0.2-0.31.1
Bone: trabecular spacing0.30.41.70.91.00.40.31.30.40.3-0.40.60.3-1.10.7-0.10.51.20.30.60.60.30.3-0.6
Bone: trabecular thickness0.70.84.70.2-0.10.50.8-0.50.90.51.00.70.92.20.31.20.6-0.20.80.70.70.90.81.5
Bone: trabecular tissue density1.01.42.7-1.4-1.7-1.5-1.1-1.3-1.2-1.4-0.9-1.2-1.3-0.6-0.7-1.2-1.2-0.9-1.1-1.2-1.2-1.0-1.3-1.0
Breakpoint value in progressive ratio session0.60.71.40.60.91.01.10.10.90.91.10.61.01.00.41.10.80.11.00.60.60.80.71.2
Distance traveled before self-admin1.51.63.51.81.10.81.01.91.61.30.01.71.60.40.50.90.81.31.01.71.71.11.5-0.1
Distance traveled after self-admin1.71.96.12.21.60.50.82.51.71.3-0.51.71.6-0.40.50.40.81.60.91.71.71.01.6-0.7
Delta time in closed arm before/after self-admin0.40.41.0-0.0-0.3-0.8-0.70.5-0.3-0.2-1.0-0.1-0.2-0.9-1.0-0.9-0.8-0.4-0.7-0.1-0.2-0.7-0.2-0.9
Delta time in open arm before/after self-admin0.30.31.2-0.9-0.4-0.1-0.2-1.1-0.7-0.40.3-0.6-0.8-0.00.4-0.2-0.0-0.3-0.2-0.6-0.6-0.2-0.60.3
Diff in mean of infusions in LGA sessions0.20.20.70.70.50.70.70.70.50.20.1-0.10.70.10.50.30.50.90.5-0.1-0.10.40.4-0.3
Extinction: sum of active levers before priming0.40.40.70.50.70.60.80.20.60.60.50.50.70.40.90.40.70.40.90.50.50.80.50.7
Active lever presses in extinction session 61.81.72.80.91.21.61.40.71.11.21.21.71.21.60.91.61.30.81.21.71.71.11.11.5
Delta distance traveled before/after self-admin0.40.41.4-0.0-0.3-0.7-0.80.3-0.3-0.5-0.9-0.6-0.5-1.2-0.7-0.9-0.7-0.2-0.7-0.6-0.6-0.6-0.4-1.1
Delta ambulatory time before/after self-admin0.30.30.6-0.2-0.3-0.7-0.6-0.2-0.3-0.5-0.6-0.8-0.4-0.8-0.5-0.7-0.6-0.4-0.5-0.8-0.8-0.3-0.3-0.6
Time in closed arm before self-admin1.41.62.6-1.4-1.3-1.2-1.5-1.0-1.5-1.0-0.7-1.3-1.6-1.1-1.4-1.1-1.3-1.3-1.5-1.3-1.2-1.6-1.3-1.0
Time in closed arm after self-admin1.21.32.3-0.6-0.8-1.2-1.40.0-0.9-0.6-1.1-1.0-1.0-1.5-1.5-1.3-1.3-0.9-1.3-1.0-1.0-1.4-1.0-1.5
Time in open arm before self-admin1.61.77.72.21.40.40.72.81.50.8-1.01.31.6-0.60.50.00.61.90.71.31.30.91.2-1.2
Time in open arm after self-admin2.83.15.01.91.91.82.01.61.91.30.91.71.91.12.21.62.02.21.91.71.72.12.00.9
Sum of active levers in priming session hrs 5-60.60.51.2-0.9-0.4-0.9-0.9-0.7-1.0-0.5-0.5-0.4-0.8-0.9-0.4-1.1-0.6-0.8-0.6-0.4-0.5-0.9-1.0-0.4
Time to tail flick, vehicle, before self-admin0.20.20.70.3-0.2-0.5-0.10.80.20.2-0.70.70.3-0.2-0.5-0.1-0.30.2-0.20.70.6-0.00.7-0.7
Time to tail flick, vehicle, after self-admin0.60.62.3-0.30.00.80.8-0.90.30.31.20.50.31.50.81.10.7-0.00.80.50.50.70.41.5
Time to tail flick, test, before self-admin0.30.31.40.60.40.1-0.41.20.1-0.1-0.70.1-0.1-0.9-0.1-0.50.00.7-0.40.10.1-0.10.1-1.0
Time to tail flick, test, after self-admin0.10.10.3-0.3-0.10.40.2-0.3-0.2-0.10.5-0.2-0.10.6-0.00.60.20.00.0-0.2-0.2-0.00.20.3
Delta time to tail flick, vehicle, before/after SA1.01.04.7-1.0-0.20.90.6-2.0-0.3-0.11.7-0.4-0.31.70.61.00.6-0.80.6-0.4-0.40.3-0.42.2
Delta time to tail flick, test, before/after SA0.50.52.4-1.0-0.70.10.1-1.5-0.5-0.20.9-0.7-0.40.9-0.10.5-0.1-0.90.0-0.7-0.7-0.1-0.40.9
Ambulatory time before self-admin1.61.63.91.81.20.70.92.01.61.30.01.81.60.40.60.70.81.31.01.81.81.01.5-0.1
Ambulatory time after self-admin1.01.13.51.71.10.40.61.91.41.0-0.31.31.3-0.10.20.40.51.10.61.31.30.81.4-0.4
Total heroin consumption0.10.10.20.20.1-0.10.10.00.30.30.20.20.30.3-0.50.3-0.1-0.50.10.20.20.10.20.3
Area under the delay curve0.30.40.90.70.40.40.90.40.90.10.10.20.90.60.70.40.60.70.80.20.20.90.60.4
Delay disc. indifference point, 0s delay0.30.41.0-0.6-0.7-0.7-0.3-0.6-0.5-0.6-0.4-1.0-0.4-0.4-0.4-0.4-0.6-0.5-0.4-1.0-1.0-0.4-0.5-0.3
Delay disc. indifference point, 16s delay1.61.63.01.61.21.01.61.21.70.60.31.11.71.01.40.91.31.51.51.11.11.71.50.6
Delay disc. indifference point, 2s delay0.40.52.4-0.9-0.9-0.20.2-1.5-0.2-0.60.6-0.8-0.21.0-0.20.5-0.3-1.00.1-0.8-0.80.1-0.51.0
Delay disc. indifference point, 24s delay2.12.03.31.11.21.21.70.41.40.81.01.61.41.61.81.31.61.21.71.61.61.71.51.5
Delay disc. indifference point, 4s delay0.20.20.50.7-0.0-0.10.30.70.7-0.1-0.5-0.20.7-0.0-0.3-0.1-0.20.40.2-0.2-0.20.40.4-0.5
Delay disc. indifference point, 8s delay0.60.71.3-0.8-1.0-1.0-0.7-0.8-0.7-1.2-0.7-0.9-0.7-0.4-0.5-1.1-0.8-0.7-0.7-0.9-0.9-0.6-0.9-0.4
Delay discount exponential model param0.50.51.2-0.8-0.6-0.6-1.1-0.4-1.1-0.2-0.3-0.4-1.0-0.8-0.9-0.6-0.7-0.8-0.9-0.4-0.4-1.1-0.8-0.6
Delay discount hyperbolic model param0.30.30.7-0.5-0.3-0.4-0.9-0.0-0.80.0-0.3-0.1-0.7-0.7-0.6-0.5-0.5-0.4-0.7-0.1-0.1-0.9-0.5-0.5
Fecal boli incidents, locomotor time 10.20.21.30.00.3-0.1-0.20.4-0.20.3-0.21.2-0.1-0.20.30.10.20.3-0.01.21.2-0.20.3-0.2
Change in fecal boli incidents, locomotor task0.30.31.00.90.50.30.70.70.9-0.0-0.20.20.80.10.80.10.51.00.60.20.20.80.2-0.2
Time >=10cm from walls, locomotor time 11.31.34.9-0.0-0.4-0.9-1.51.0-0.8-0.6-1.6-0.3-1.0-1.9-1.2-1.3-1.00.1-1.5-0.3-0.3-1.4-1.3-2.2
Bouts of movement, locomotor time 10.20.30.9-0.4-0.5-0.5-0.6-0.2-0.6-0.7-0.5-0.6-0.6-0.5-0.2-0.9-0.4-0.1-0.6-0.6-0.6-0.4-0.3-0.6
Total resting periods, locomotor time 10.30.30.8-0.4-0.5-0.4-0.6-0.2-0.5-0.7-0.6-0.7-0.6-0.5-0.3-0.9-0.4-0.0-0.6-0.7-0.7-0.5-0.4-0.6
Rest time, locomotor task time 12.42.64.5-1.8-1.8-1.5-1.9-1.5-1.8-1.3-0.8-1.4-2.0-1.0-1.7-1.8-1.7-1.7-1.8-1.4-1.4-1.8-2.1-0.8
Distance moved, locomotor task time 11.61.82.81.61.51.51.61.21.61.00.81.01.71.01.41.41.41.51.51.01.01.61.40.8
Vertical activity count, locomotor time 11.01.12.01.31.00.81.11.01.40.90.51.01.40.90.81.10.91.01.21.01.01.31.20.6
Time >=10cm from walls, locomotor time 20.30.31.81.00.50.30.11.30.60.5-0.40.30.6-0.2-0.60.1-0.00.5-0.00.30.30.10.7-0.6
Bouts of movement, locomotor time 20.10.10.30.20.30.40.30.30.1-0.00.10.10.20.20.40.60.30.50.20.10.10.20.4-0.1
Total resting periods, locomotor time 20.10.10.30.0-0.1-0.1-0.20.2-0.2-0.3-0.4-0.2-0.2-0.4-0.0-0.0-0.10.3-0.3-0.2-0.2-0.2-0.0-0.6
Rest time, locomotor task time 20.91.02.8-0.4-0.8-1.0-1.10.1-0.7-1.0-1.2-1.1-0.9-1.5-0.6-1.5-0.9-0.0-1.0-1.1-1.1-0.9-1.1-1.7
Distance moved, locomotor task time 20.10.20.30.50.40.30.40.40.50.50.20.30.60.4-0.10.40.20.00.40.30.30.40.50.4
Vertical activity count, locomotor time 20.30.31.6-0.40.00.30.1-0.6-0.10.50.80.6-0.01.0-0.30.70.1-0.90.10.60.6-0.00.01.3
Weight adjusted by age0.91.02.21.31.01.01.41.21.30.50.20.51.40.41.10.71.01.51.20.50.51.20.8-0.0
Seeking ratio, delayed vs. immediate footshock0.91.02.01.31.31.21.21.11.20.80.50.61.20.51.40.71.21.41.20.60.71.20.80.4
Locomotion in novel chamber1.01.23.01.61.01.01.01.71.41.00.11.21.40.40.50.90.81.40.81.21.21.01.3-0.2
Locomotion in novel chamber post-restriction0.80.92.30.40.61.01.0-0.30.80.81.21.10.61.50.91.11.00.40.91.11.00.90.71.4
Progressive ratio0.10.20.40.40.40.20.60.20.50.30.20.20.60.20.50.40.40.30.60.20.20.60.60.2
Food seeking constrained by brief footshock2.22.73.81.21.81.81.80.61.61.91.91.61.71.61.51.61.70.82.01.61.61.71.91.9
Seeking ratio, punishment vs. effort0.30.40.70.50.80.80.50.40.50.90.70.80.50.60.40.50.70.30.60.80.80.50.70.8
Run reversals in cocaine runway, females0.90.93.31.61.00.70.71.81.20.5-0.20.81.20.20.70.30.71.70.60.80.80.91.3-0.4
Run reversals in cocaine runway, males0.40.31.10.90.40.40.41.00.80.3-0.30.80.80.20.30.30.30.80.40.80.80.50.4-0.3
Latency to leave start box in cocaine runway0.10.10.50.50.2-0.1-0.10.60.30.0-0.5-0.00.2-0.4-0.10.2-0.10.4-0.1-0.0-0.00.10.3-0.7
Latency to leave start box in cocaine runway, F0.40.52.31.20.4-0.30.01.50.80.4-0.80.50.7-0.7-0.1-0.1-0.00.90.10.50.50.30.8-1.1
Latency to leave start box in cocaine runway, M0.50.51.1-0.9-0.5-0.2-0.5-1.0-0.8-0.70.1-1.0-0.8-0.2-0.40.0-0.4-0.8-0.5-1.0-1.0-0.6-0.90.0
Cd content in liver2.02.15.4-1.0-1.1-1.6-1.4-0.2-1.5-1.3-1.6-1.4-1.5-2.3-1.0-2.0-1.4-0.5-1.6-1.4-1.4-1.5-1.5-2.0
Co content in liver0.10.10.7-0.3-0.2-0.3-0.3-0.1-0.50.1-0.2-0.0-0.4-0.8-0.3-0.4-0.4-0.4-0.4-0.0-0.0-0.5-0.4-0.3
Cu content in liver0.20.31.3-0.7-0.40.3-0.1-1.2-0.4-0.10.8-0.3-0.50.8-0.10.40.0-0.7-0.1-0.3-0.3-0.2-0.50.9
Fe content in liver2.02.33.6-1.8-1.6-1.4-1.7-1.6-1.7-1.2-0.7-1.5-1.8-1.0-1.6-1.4-1.6-1.9-1.6-1.5-1.5-1.7-1.9-0.7
K content in liver0.50.51.9-1.0-0.60.0-0.3-1.4-0.6-0.30.5-0.4-0.70.7-0.70.1-0.4-1.3-0.4-0.4-0.4-0.5-0.60.9
Mg content in liver2.82.96.6-2.4-1.7-1.1-1.5-2.6-2.0-1.5-0.1-1.8-2.2-0.4-1.5-1.2-1.4-2.3-1.6-1.8-1.8-1.7-2.10.3
Mn content in liver4.45.010.2-3.0-2.6-1.8-2.0-3.2-2.5-2.0-0.5-2.4-2.6-0.4-2.3-1.6-2.1-3.2-2.1-2.4-2.4-2.2-2.5-0.0
Na content in liver0.40.41.7-0.9-0.50.0-0.4-1.3-0.50.10.8-0.6-0.60.5-0.60.3-0.3-1.2-0.2-0.6-0.6-0.4-0.50.8
Rb content in liver3.54.47.5-2.1-2.0-1.8-1.9-2.0-2.1-2.0-1.1-2.7-2.3-1.8-2.0-2.1-2.1-2.2-2.1-2.7-2.7-2.0-2.4-1.3
Se content in liver0.91.12.5-0.7-0.6-1.0-1.1-0.2-1.1-1.2-1.2-1.0-1.1-1.6-0.6-1.4-0.9-0.3-1.1-1.0-1.0-1.1-1.2-1.2
Sr content in liver0.90.81.91.10.80.60.81.41.00.80.11.11.10.50.60.60.71.10.71.11.10.81.20.1
Zn content in liver0.10.10.3-0.5-0.4-0.1-0.2-0.4-0.5-0.30.1-0.2-0.40.2-0.2-0.2-0.2-0.3-0.3-0.2-0.2-0.4-0.50.1