Hub : Genes

Matn2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000008361 0.13 0.07 2.3e-15 0.09 0.12 0.11 0.12 2.2e-10 6.4e-13 2.2e-12 1.7e-13
2 Adipose alternative polyA ENSRNOT00000106400 0.13 0.07 1.7e-15 0.1 0.12 0.11 0.12 1.2e-11 5.0e-13 4.2e-12 1.3e-13
3 Adipose alternative polyA ENSRNOT00000008361 0.13 0.07 1.7e-15 0.09 0.12 0.11 0.12 1.9e-10 4.9e-13 1.8e-12 2.0e-13
4 Adipose alternative polyA ENSRNOT00000106400 0.13 0.07 6.4e-15 0.1 0.11 0.11 0.12 8.3e-11 1.2e-12 1.7e-12 1.0e-13
5 Adipose isoform ratio ENSRNOT00000106400 0.04 0.03 4.1e-04 0.01 0.01 0.01 0.01 7.3e-03 3.6e-02 5.8e-02 4.3e-02
6 BLA gene expression ENSRNOG00000006060 0.11 0.08 8.0e-05 0.04 0.06 0.06 0.04 2.4e-03 5.6e-04 2.4e-04 4.4e-03
7 BLA isoform ratio ENSRNOT00000100118 0.05 0.04 2.7e-03 0.04 0.05 0.03 0.05 5.4e-03 8.2e-04 1.2e-02 1.1e-03
8 Brain gene expression ENSRNOG00000006060 0.1 0.05 2.8e-10 0.1 0.1 0.11 0.12 6.0e-10 1.2e-09 1.6e-10 5.7e-11
9 Brain isoform ratio ENSRNOT00000106400 0.07 0.06 1.4e-03 0.03 0.02 0.02 0.02 1.9e-03 5.2e-03 3.3e-03 3.7e-03
10 IL isoform ratio ENSRNOT00000100118 0.13 0.08 3.0e-03 0.05 0.08 0.12 0.09 2.9e-02 5.8e-03 1.0e-03 3.1e-03
11 LHb gene expression ENSRNOG00000006060 0.24 0.12 5.6e-05 0.14 0.14 0.2 0.19 3.0e-04 3.4e-04 1.9e-05 2.5e-05
12 Liver gene expression ENSRNOG00000006060 0.03 0.02 1.6e-03 0.01 0.02 0.01 0.01 2.9e-02 1.6e-03 5.0e-02 3.3e-02
13 NAcc gene expression ENSRNOG00000006060 0.08 0.05 5.9e-07 0.08 0.09 0.08 0.09 1.0e-06 6.6e-07 2.3e-06 5.9e-07
14 PL isoform ratio ENSRNOT00000100118 0.07 0.06 1.3e-04 0.05 0.04 0.04 0.06 1.5e-04 5.7e-04 5.0e-04 2.8e-05
15 PL isoform ratio ENSRNOT00000106400 0.04 0.04 5.3e-03 0.02 0.01 0.01 0.01 2.0e-02 3.3e-02 3.5e-02 4.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail1.54.76.1-2.32.3-2.32.32.2-2.4-2.0-2.22.5-0.1-2.3-1.6-2.3-2.42.5
BMI without tail0.10.20.6-0.30.4-0.30.4-0.0-0.60.00.10.40.8-0.50.3-0.3-0.40.3
Body weight1.14.56.1-2.12.2-2.12.32.1-2.1-2.4-2.22.50.3-1.8-2.3-2.1-2.32.4
Epididymis fat weight0.20.54.9-0.40.3-0.40.21.1-0.3-0.3-0.9-0.0-2.20.1-0.5-0.40.1-0.1
Glucose1.42.22.91.7-1.71.7-1.7-1.61.21.71.3-1.50.31.11.51.71.5-1.4
Heart weight0.30.41.70.4-0.30.4-0.3-0.11.3-0.7-0.0-0.21.00.8-1.10.20.2-0.2
Left kidney weight0.20.65.70.00.10.00.20.40.4-0.8-0.20.12.40.6-1.0-0.2-0.30.1
Right kidney weight0.20.67.20.2-0.10.20.0-0.20.6-0.60.4-0.02.70.7-0.70.1-0.1-0.0
Tail length0.20.61.00.9-0.80.9-0.7-1.00.50.60.9-0.51.00.60.60.90.7-0.6
Length with tail0.20.61.4-0.60.6-0.60.71.0-0.5-1.0-1.10.7-0.7-0.3-1.2-0.5-0.60.8
Length without tail2.04.48.5-2.01.9-2.01.92.6-1.4-2.6-2.82.1-1.5-1.2-2.9-1.8-1.92.1
Liver weight, left0.10.20.60.7-0.60.7-0.6-0.30.40.20.2-0.20.20.3-0.10.70.3-0.3
Liver weight, right0.20.40.70.8-0.80.8-0.7-0.50.7-0.10.5-0.30.60.8-0.40.80.6-0.3
Parametrial fat weight2.34.47.1-2.02.1-2.02.31.4-1.5-2.7-1.52.42.0-1.5-2.4-2.2-2.62.4
Retroperitoneal fat weight0.10.51.9-0.60.6-0.60.50.9-0.8-0.2-0.90.5-1.4-0.7-0.1-0.6-0.50.4
Intraocular pressure0.50.61.30.8-0.80.8-0.7-1.10.20.91.1-0.90.40.30.90.90.7-0.8
Extensor digitorum longus weight0.20.84.00.6-0.60.6-0.6-0.60.81.70.7-0.8-0.7-0.32.00.70.6-0.7
Soleus weight0.30.81.7-1.11.1-1.11.10.5-0.6-0.8-0.71.10.3-0.9-0.6-1.0-0.91.3
Tibialis anterior weight0.41.54.61.0-0.91.0-0.8-1.21.21.91.4-1.40.40.42.11.10.9-1.2
Tibia length1.02.93.8-1.81.8-1.81.91.7-1.9-1.6-1.91.8-0.6-1.7-1.4-1.8-1.81.7
Number of licking bursts0.40.51.1-0.70.6-0.70.61.1-0.7-0.8-0.80.6-0.7-0.4-0.8-0.9-0.50.6
Food consumed during 24 hour testing period0.10.10.60.3-0.30.3-0.2-0.2-0.30.2-0.1-0.10.8-0.30.10.20.0-0.1
Times rat made contact with spout0.40.51.4-0.60.6-0.60.60.6-0.4-1.0-0.80.8-0.1-0.3-1.2-0.6-0.60.8
Mean time between licks in bursts0.20.30.6-0.40.4-0.40.40.7-0.2-0.8-0.60.50.8-0.3-0.8-0.7-0.50.5
Mean num. licks in bursts0.20.20.60.4-0.40.4-0.3-0.80.40.60.5-0.40.30.10.60.60.4-0.4
Std. dev. time between licks in bursts0.00.00.1-0.20.2-0.20.20.3-0.1-0.1-0.20.20.2-0.3-0.1-0.3-0.20.2
Water consumed over 24 hours0.40.41.5-0.50.5-0.50.50.4-1.2-0.5-0.70.90.0-1.0-0.4-0.5-0.50.9
Indifference point 0 sec0.20.42.3-0.30.2-0.30.20.40.40.8-0.2-0.5-1.5-0.31.1-0.40.1-0.4
Indifference point AUC0.40.50.80.7-0.80.7-0.8-0.50.90.90.5-0.8-0.00.60.80.70.8-0.8
Indifference point function ln k0.71.01.9-1.11.1-1.11.01.1-1.4-0.7-1.11.0-0.9-1.1-0.6-1.0-0.91.1
Indifference point function log k0.71.01.9-1.11.1-1.11.01.1-1.4-0.7-1.11.0-0.9-1.1-0.6-1.0-0.91.1
Delay discounting total patch changes 0 sec0.20.31.9-0.30.3-0.30.20.40.40.6-0.3-0.4-1.4-0.30.9-0.40.0-0.3
Delay discounting total patch changes 12 sec0.50.61.50.7-0.70.7-0.7-0.71.20.80.7-0.90.50.70.70.60.6-0.9
Delay discounting total patch changes 18 sec0.20.21.70.1-0.00.10.0-0.31.30.30.4-0.50.40.50.40.00.2-0.5
Delay discounting total patch changes 24 sec0.10.11.00.1-0.00.00.1-0.21.00.10.4-0.30.80.40.20.00.1-0.4
Delay discounting total patch changes 6 sec1.82.76.41.5-1.51.5-1.5-1.31.42.41.5-2.0-0.11.12.51.41.7-2.0
Delay discounting time to switch 0 sec0.10.20.5-0.30.4-0.30.50.1-0.1-0.7-0.00.50.7-0.2-0.7-0.4-0.60.6
Delay discounting water rate 0 sec0.20.30.8-0.60.5-0.60.40.7-0.7-0.3-0.90.4-0.8-0.3-0.4-0.4-0.40.4
Delay discounting water rate 12 sec0.20.31.5-0.50.5-0.50.50.3-0.90.1-0.30.51.2-0.80.3-0.4-0.50.4
Delay discounting water rate 18 sec0.30.40.80.7-0.70.7-0.8-0.20.00.70.2-0.70.80.60.40.70.9-0.8
Delay discounting water rate 24 sec0.71.02.5-1.01.0-1.00.91.1-0.7-1.4-1.01.0-0.2-0.3-1.6-0.9-1.01.0
Delay discounting water rate 6 sec0.10.11.3-0.0-0.1-0.0-0.10.30.20.1-0.4-0.4-1.10.4-0.00.10.2-0.4
Locomotor activity0.81.33.61.2-1.21.2-1.2-0.91.60.10.6-0.91.91.5-0.41.11.0-0.9
Locomotor testing distance1.83.07.31.9-1.81.8-1.8-1.92.10.61.6-1.42.71.90.21.71.6-1.4
Locomotor testing rearing1.42.26.71.3-1.21.3-1.1-1.62.60.51.6-1.42.21.90.21.21.1-1.3
Light reinforcement 10.00.10.4-0.10.1-0.10.20.10.2-0.4-0.2-0.00.60.2-0.5-0.2-0.1-0.0
Light reinforcement 20.70.98.8-0.60.5-0.60.41.1-0.70.2-1.00.2-3.0-0.80.3-0.6-0.30.1
Reaction time number correct0.81.13.8-1.01.0-1.01.00.9-1.0-1.7-0.91.00.5-0.1-2.0-0.9-0.91.0
Reaction time mean minus median0.50.64.2-0.80.7-0.70.61.0-0.6-0.3-0.90.3-2.1-0.4-0.3-0.8-0.30.3
Reaction time mean minus median AUC0.30.34.1-0.0-0.10.0-0.10.5-0.30.1-0.3-0.3-2.00.3-0.1-0.10.4-0.3
Reaction time num false alarms0.20.22.20.10.00.10.1-0.40.70.20.5-0.31.50.30.4-0.1-0.2-0.2
Reaction time num false alarms AUC0.40.65.30.5-0.40.4-0.3-0.80.90.20.8-0.42.30.60.20.30.1-0.4
Reaction time trials correct on left0.81.13.8-1.01.0-1.01.00.9-1.0-1.7-0.91.00.5-0.1-2.0-0.9-0.91.0
Reaction time trials on left0.81.23.9-1.01.0-1.01.01.0-1.0-1.7-1.01.00.3-0.1-2.0-0.9-0.91.0
Reaction time mean0.30.44.3-0.60.5-0.50.40.7-0.0-0.1-0.3-0.2-2.10.3-0.0-0.6-0.3-0.2
Reaction time mean AUC0.40.54.8-0.60.5-0.50.40.80.0-0.1-0.3-0.3-2.20.5-0.1-0.5-0.2-0.3
Median of all reaction times0.40.54.2-0.60.6-0.60.50.90.2-0.3-0.4-0.2-2.10.4-0.3-0.7-0.4-0.1
Reaction time omissions0.81.12.01.0-1.11.0-1.1-0.40.91.20.8-1.4-0.31.21.01.01.2-1.4
Reaction time false alarm rate0.81.25.40.9-0.80.9-0.7-1.31.21.01.3-0.82.30.51.20.70.4-0.8
Reaction time premature initiation rate0.50.71.90.8-0.70.8-0.7-0.91.40.41.0-0.71.11.00.30.60.7-0.7
Reaction time premature initiations0.20.20.90.2-0.20.2-0.2-0.30.7-0.50.3-0.10.90.9-0.80.10.2-0.1
Std. dev. reaction times0.40.56.5-0.20.1-0.2-0.00.7-0.1-0.1-0.5-0.3-2.60.4-0.2-0.30.3-0.2
Reaction time trials completed0.81.23.9-1.01.0-1.01.01.0-1.0-1.7-1.01.00.3-0.1-2.0-0.9-0.91.0
Reaction time trials AUC0.60.93.3-0.80.8-0.80.80.8-0.8-1.5-0.80.90.40.0-1.8-0.7-0.70.9
Social response proportion2.02.217.0-1.00.8-1.00.62.0-0.7-0.7-2.10.5-4.1-0.6-1.0-0.9-0.50.5
Social responses0.91.213.00.6-0.70.6-0.80.30.20.6-0.4-0.7-3.60.40.20.60.7-0.7
Social time0.71.09.10.5-0.60.5-0.8-0.20.21.00.0-0.7-3.00.11.00.50.8-0.7
Conditioned locomotion0.91.01.5-1.01.0-1.01.01.1-0.9-1.2-1.01.10.3-0.9-1.2-1.0-1.21.2
Cocaine response after cond. corrected0.40.44.60.5-0.50.5-0.5-0.6-0.20.40.3-0.02.1-0.00.40.60.2-0.1
Cocaine response after cond. not corrected1.21.48.11.1-1.11.1-1.1-1.30.30.80.9-0.62.90.70.71.40.8-0.6
Cocaine response before conditioning1.01.22.11.2-1.21.2-1.1-1.21.10.71.1-1.10.81.40.41.41.1-1.0
Saline control response1.92.53.71.7-1.61.7-1.6-1.70.81.91.8-1.70.61.11.91.71.5-1.6
Condit. Reinf. active minus inactive responses2.32.83.81.7-1.81.7-1.8-1.51.91.11.7-1.81.72.00.71.71.7-1.9
Condit. Reinf. active-inactive response ratio0.80.81.40.8-0.80.8-0.8-0.71.20.81.0-1.10.61.00.70.71.1-1.2
Condit. Reinf. active responses4.25.87.92.5-2.52.5-2.5-2.42.81.42.4-2.52.82.80.92.52.3-2.6
Condit. Reinf. inactive responses2.32.93.81.8-1.81.8-1.8-1.81.91.01.7-1.71.71.90.61.81.6-1.8
Condit. Reinf. lever presses1.11.52.21.3-1.41.3-1.4-0.91.40.71.0-1.41.31.20.41.01.5-1.4
Condit. Reinf. lever reinforcers received4.25.98.32.5-2.52.5-2.5-2.42.71.62.5-2.52.92.71.12.52.3-2.6
Pavlov. Cond. lever latency1.52.03.1-1.51.6-1.51.71.0-1.8-1.4-1.11.6-0.3-1.1-1.2-1.3-1.61.6
Pavlov. Cond. magazine entry latency0.10.10.30.1-0.20.2-0.20.00.60.20.1-0.3-0.30.10.1-0.00.4-0.3
Pavlov. Cond. change in total contacts0.40.51.20.6-0.70.6-0.7-0.21.10.90.4-0.9-0.60.30.80.40.7-0.9
Pavlov. Cond. index score0.40.50.80.7-0.80.8-0.9-0.40.90.80.4-0.80.10.30.70.50.9-0.8
Pavlov. Cond. latency score0.20.30.50.5-0.60.5-0.7-0.20.70.60.3-0.60.00.10.50.40.6-0.6
Pavlov. Cond. lever contacts1.21.62.81.4-1.51.4-1.5-0.91.71.21.0-1.50.11.01.01.11.4-1.5
Pavlov. Cond. magazine entry number0.00.10.3-0.10.1-0.10.2-0.0-0.6-0.1-0.10.40.1-0.2-0.10.0-0.30.3
Pavlov. Cond. intertrial magazine entries0.81.03.7-1.01.0-1.01.01.0-1.2-0.5-0.90.8-1.9-0.9-0.3-1.1-0.60.8
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.7-0.70.7-0.8-0.30.80.70.4-0.7-0.10.10.60.40.8-0.7
Pavlov. Cond. response bias1.21.62.71.4-1.51.4-1.6-0.91.61.11.0-1.50.51.10.81.21.5-1.4
Conditioned reinforcement - actives0.40.40.9-0.50.6-0.50.60.5-0.9-0.1-0.40.70.8-0.90.2-0.6-0.70.7
Conditioned reinforcement - inactives0.50.53.00.5-0.40.5-0.4-0.81.1-0.20.9-0.31.70.8-0.40.50.3-0.3
Conditioned locomotion0.30.30.70.5-0.60.5-0.70.20.80.3-0.1-0.7-0.60.90.00.40.7-0.7
Intermittent access intake day 1-15 change2.82.710.61.6-1.51.6-1.5-1.51.31.61.6-1.43.31.21.51.51.4-1.4
Intermittent access intake escalation3.13.111.21.7-1.61.7-1.6-1.61.61.51.7-1.63.31.51.41.61.6-1.6
Intermittent access intake escalation 23.03.028.51.2-1.11.2-0.9-1.61.10.61.6-0.85.31.20.51.10.8-0.8
Intermitt. access day 1 inactive lever presses0.70.82.60.8-0.80.8-0.8-0.51.4-0.30.5-0.81.11.6-0.80.70.8-0.8
Intermitt. access day 15 inactive lever presses2.72.93.91.8-1.81.8-1.7-1.91.71.32.0-1.71.71.71.01.91.7-1.7
Intermitt. access escalation Index0.80.88.3-0.30.1-0.3-0.11.10.1-0.2-1.0-0.2-2.90.3-0.4-0.30.2-0.2
Intermittent access day 1 total infusions0.20.31.00.4-0.40.4-0.4-0.20.10.90.3-0.4-0.7-0.11.00.40.4-0.4
Intermittent access day 15 total infusions1.61.85.41.3-1.31.3-1.2-1.11.11.41.4-1.22.30.91.41.31.2-1.2
Intermittent access terminal intake (last 3 days)0.80.84.20.7-0.70.7-0.7-0.70.51.10.9-0.72.10.31.20.80.7-0.7
Intermittent access total infusions0.70.81.40.8-0.80.8-0.8-0.80.71.11.0-0.81.20.51.10.90.8-0.8
Intermittent access day 1 locomotion0.60.61.10.8-0.90.8-0.9-0.40.61.00.5-0.9-0.40.61.00.80.9-0.9
Intermittent access day 15 total locomotion1.61.78.41.3-1.21.2-1.0-1.31.01.01.2-1.02.90.91.01.11.0-1.0
Intermittent access total locomotion0.60.71.00.9-0.90.9-0.9-0.70.81.00.5-0.90.30.70.90.80.9-0.9
Intermittent access standard deviation1.11.22.41.2-1.11.2-1.1-0.90.71.50.9-1.01.00.51.61.01.0-1.0
Cocaine induced anxiety0.40.53.4-0.30.2-0.30.20.41.1-0.8-0.40.1-1.80.5-1.1-0.2-0.10.1
Post-drug Anxiety1.21.32.31.1-1.21.1-1.2-1.01.51.21.2-1.2-0.01.01.01.21.2-1.2
Baseline Anxiety0.70.71.70.9-0.80.9-0.8-0.8-0.11.00.8-0.71.30.31.10.70.7-0.7
Lifetime Intake1.11.22.21.0-1.01.0-1.0-1.00.81.41.2-1.01.20.51.51.11.0-1.0
Incentive Sensitization - Responses0.10.10.3-0.10.1-0.10.10.2-0.0-0.4-0.20.10.20.3-0.5-0.2-0.10.1
Incentive Sensitization - Breakpoint0.10.10.3-0.10.1-0.10.10.20.0-0.4-0.20.10.20.3-0.6-0.2-0.10.1
Progressive ratio test 1 active lever presses0.70.71.80.8-0.80.8-0.8-0.90.51.31.0-0.80.40.31.40.90.8-0.8
Progressive ratio test 1 breakpoint0.90.92.30.9-0.90.9-1.0-0.90.61.51.0-1.0-0.00.41.51.01.0-1.0
Progressive ratio test 1 inactive lever presses2.42.58.71.5-1.41.5-1.4-1.51.90.91.8-1.43.01.60.61.51.4-1.4
Progressive ratio test 2 active lever presses1.21.32.41.1-1.21.1-1.3-0.80.81.50.9-1.3-0.40.81.41.11.3-1.3
Progressive ratio test 2 breakpoint1.21.42.51.2-1.21.2-1.3-0.90.81.60.9-1.3-0.30.81.51.11.3-1.3
Progressive ratio test 2 inactive lever presses2.22.57.91.5-1.51.5-1.4-1.61.71.11.9-1.42.81.50.81.61.4-1.4
Total sessions with >9 infusions2.93.213.31.6-1.51.6-1.3-2.20.91.82.4-1.23.60.82.01.61.2-1.2
Short access day 1 total inactive lever presses1.11.23.50.9-1.00.9-1.0-1.11.90.41.3-1.01.41.40.01.11.0-1.0
Short access day 10 total inactive lever presses2.02.29.91.4-1.41.4-1.2-1.71.10.81.7-1.23.21.40.61.41.2-1.2
Short access day 1 total infusions0.10.10.4-0.30.3-0.30.30.1-0.10.30.10.3-0.2-0.70.5-0.2-0.30.3
Short access day 10 total infusions0.40.43.80.1-0.10.1-0.20.4-0.20.9-0.2-0.3-2.0-0.41.00.00.3-0.3
Short access total infusions1.11.23.11.0-1.11.0-1.1-0.60.81.70.8-1.1-0.80.41.81.01.1-1.1
Short access day 1 locomotion0.50.52.20.5-0.50.5-0.4-0.91.00.40.9-0.41.50.40.50.60.4-0.4
Short access day 10 total locomotion1.51.72.51.5-1.51.5-1.5-0.91.01.60.9-1.5-0.41.11.51.21.5-1.5
Short access total locomotion3.03.14.72.0-2.02.0-2.0-1.22.21.71.2-2.00.31.91.41.72.0-2.0
Compulsive drug intake2.92.97.3-1.71.6-1.71.51.6-1.2-2.0-1.81.5-2.7-0.8-2.1-1.6-1.51.5
One hour access (0.3 mA shock)0.10.10.7-0.20.2-0.20.10.00.20.00.10.10.8-0.20.1-0.1-0.10.1
One hour access (shock baseline)1.11.36.21.0-0.91.0-0.8-1.10.81.21.3-0.82.50.41.31.00.8-0.8
Number of responses in last shaping day0.90.91.6-1.11.1-1.11.10.8-0.4-0.7-0.81.20.8-1.3-0.4-1.0-1.21.2
Context. condit. distance diff. score0.30.32.0-0.60.5-0.60.50.7-0.00.2-0.4-0.0-1.4-0.20.4-0.6-0.5-0.1
Locomotion velocity, session 11.11.14.3-1.01.0-1.00.90.8-0.6-1.8-0.91.00.3-0.1-2.1-0.9-0.90.9
Locomotion distance, session 13.24.16.8-1.81.8-1.81.81.9-2.1-2.5-2.32.4-1.2-1.6-2.6-2.1-1.72.3
Locomotion velocity, session 20.50.52.5-0.60.6-0.60.60.2-0.4-1.4-0.70.8-0.3-0.0-1.6-0.6-0.40.6
Locomotion distance, session 20.10.20.50.2-0.20.2-0.2-0.3-0.7-0.4-0.30.70.7-0.4-0.50.20.10.4
Locomotion velocity, session 31.11.32.5-0.90.9-0.91.00.9-1.3-1.4-1.41.50.5-0.8-1.6-0.8-0.91.5
Locomotion distance, session 30.30.30.7-0.20.2-0.20.20.4-0.6-0.5-0.80.80.7-0.8-0.5-0.2-0.40.7
Stereotopy head waving bouts, day 30.10.10.8-0.10.1-0.10.1-0.1-0.30.10.2-0.3-0.90.60.10.10.1-0.2
Stereotopy head waving duration, day 30.10.10.90.1-0.10.1-0.1-0.3-0.1-0.10.1-0.2-1.00.7-0.30.40.1-0.1
Locomotion velocity, session 74.44.96.7-2.32.2-2.32.22.4-2.5-2.0-2.52.4-0.9-2.1-1.7-2.3-2.62.3
Locomotion distance, session 70.20.31.5-0.20.1-0.20.10.5-0.70.9-0.1-0.30.1-0.51.2-0.3-0.5-0.4
Stereotopy head waving bouts, day 70.20.30.70.6-0.60.6-0.6-0.70.3-0.30.00.1-0.00.5-0.70.80.50.0
Stereotopy head waving duration, day 70.60.71.41.0-1.01.0-0.9-1.20.7-0.30.5-0.10.90.9-0.81.20.8-0.1
Locomotion velocity, session 80.50.61.5-0.80.8-0.80.70.9-0.6-0.9-1.00.5-1.2-0.4-0.9-0.8-0.60.5
Locomotion distance, session 80.20.31.1-0.30.3-0.30.30.5-1.00.1-0.70.5-0.9-0.90.2-0.3-0.40.3
Degree of sensitization distance0.60.63.10.0-0.10.0-0.10.00.31.40.7-1.3-0.40.51.80.00.1-1.2
Degree of sensitization stereotypy0.30.30.60.7-0.70.7-0.7-0.60.6-0.4-0.00.20.20.3-0.80.80.60.0
Condit. Reinf. active minus inactive responses0.91.03.80.6-0.60.6-0.6-0.21.11.80.7-1.3-0.20.42.00.70.6-1.4
Condit. Reinf. active-inactive response ratio0.70.71.70.6-0.60.6-0.6-0.21.21.30.7-1.20.00.81.30.60.7-1.3
Condit. Reinf. active responses1.01.23.20.7-0.70.7-0.7-0.71.31.61.2-1.41.30.81.80.80.5-1.4
Condit. Reinf. inactive responses0.40.52.60.4-0.40.4-0.3-0.80.70.41.0-0.71.60.80.40.50.2-0.6
Incentive salience index mean0.50.62.80.5-0.50.5-0.5-0.40.41.50.5-0.70.7-0.21.70.60.2-0.8
Condit. Reinf. lever presses0.10.20.60.3-0.20.3-0.2-0.4-0.40.6-0.00.10.6-0.60.70.3-0.40.1
Time in familiar zone, hab. session 11.21.12.21.3-1.31.3-1.4-1.1-0.11.40.6-0.7-0.8-0.11.40.91.5-0.6
Time in novel zone, hab. session 11.11.05.0-0.40.4-0.40.40.22.0-0.80.6-0.82.21.6-1.0-0.2-0.4-0.9
Total zone transitions, hab. session 10.30.52.20.0-0.00.00.0-0.2-1.0-0.7-0.50.91.5-0.8-0.8-0.2-0.40.9
Total locomotion distance, hab. session 11.52.28.31.7-1.61.7-1.5-1.90.90.61.5-0.92.91.20.31.51.3-1.1
Locomotion velocity, hab. session 10.81.15.41.3-1.21.3-1.1-1.40.20.10.9-0.42.30.7-0.31.10.9-0.5
Time in familiar zone, hab. session 21.41.42.31.3-1.41.3-1.4-1.11.21.11.1-1.40.21.21.01.01.5-1.2
Time in novel zone, hab. session 21.81.83.3-1.61.7-1.61.71.3-0.8-1.3-1.11.20.3-1.2-1.1-1.4-1.81.1
Total zone transitions, hab. session 20.81.03.0-0.50.5-0.50.50.9-0.9-1.4-1.51.4-0.8-0.9-1.7-0.5-0.61.3
Total locomotion distance, hab. session 20.10.21.20.1-0.10.1-0.10.1-0.3-0.7-0.50.60.3-0.2-1.10.2-0.00.4
Locomotion velocity, hab. session 20.10.10.80.3-0.30.3-0.2-0.1-0.3-0.5-0.30.50.4-0.1-0.90.30.10.2
Novel to familiar place preference ratio0.70.81.6-1.21.2-1.21.11.30.3-0.7-0.60.0-0.90.2-0.7-1.1-0.80.1
Novelty place preference0.80.92.0-1.31.3-1.31.21.40.4-0.7-0.7-0.0-0.90.2-0.6-1.2-0.80.1
Time in novel zone, NPP test1.01.12.4-1.51.4-1.51.31.50.5-0.8-0.70.0-0.70.1-0.7-1.5-1.00.1
Total zone transitions, NPP test1.01.43.2-0.80.9-0.90.90.7-1.7-1.3-1.31.80.4-1.4-1.4-0.7-1.01.6
Total locomotion distance, NPP test0.40.52.9-0.20.3-0.20.3-0.0-1.7-0.2-0.51.00.9-1.3-0.1-0.2-0.30.7
Locomotion velocity, NPP test0.40.63.8-0.30.3-0.30.40.1-2.0-0.3-0.61.10.4-1.1-0.3-0.0-0.40.9
Pavlov. Cond. lever latency0.50.74.60.3-0.20.3-0.2-0.40.9-0.40.9-0.72.11.2-0.60.20.6-0.7
Pavlov. Cond. magazine entry latency0.20.31.1-0.40.4-0.40.40.30.00.0-0.70.4-1.0-1.00.2-0.5-0.40.5
Pavlov. Cond. change in total contacts1.01.15.5-0.90.8-0.90.81.1-0.80.2-1.10.7-2.3-1.40.5-1.0-1.00.6
Pavlov. Cond. index score0.50.73.4-0.40.4-0.40.40.5-0.60.4-0.90.6-1.8-1.50.7-0.5-0.70.6
Pavlov. Cond. latency score0.50.73.5-0.40.4-0.40.40.5-0.80.4-0.90.7-1.9-1.60.7-0.4-0.60.7
Pavlov. Cond. lever contacts0.81.04.5-0.60.6-0.60.50.8-1.00.2-1.21.0-2.1-1.60.5-0.5-1.00.9
Pavlov. Cond. magazine entry number0.40.52.20.5-0.50.5-0.4-0.70.00.00.9-0.51.51.1-0.10.60.6-0.6
Pavlov. Cond. intertrial magazine entries1.31.57.21.2-1.11.2-1.1-1.40.70.61.4-0.92.71.30.41.20.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.63.6-0.40.4-0.40.40.5-0.50.3-0.90.6-1.9-1.40.6-0.5-0.70.6
Pavlov. Cond. response bias0.30.41.9-0.40.3-0.40.30.40.00.1-0.70.5-1.4-1.00.3-0.4-0.70.5
Bone: apparent density0.30.42.4-0.00.1-0.00.1-0.40.60.80.6-0.7-1.60.51.00.2-0.3-0.7
Bone surface1.32.23.9-1.71.7-1.71.81.4-0.9-1.1-1.31.4-1.7-1.2-0.9-1.5-2.01.3
Bone volume1.01.74.1-1.51.5-1.51.61.3-1.0-0.4-1.00.9-2.0-1.30.0-1.3-1.70.9
Bone: connectivity density0.50.82.20.5-0.50.5-0.5-0.81.20.90.9-1.0-1.51.01.00.60.1-1.1
Bone: cortical apparent density2.02.74.8-1.61.7-1.71.71.6-1.1-2.1-1.81.8-0.2-0.9-2.2-1.4-1.81.7
Bone: cortical area2.43.65.4-1.91.9-1.92.01.6-2.1-1.9-2.02.30.4-2.0-1.8-1.7-2.02.2
Bone: cortical porosity1.61.72.8-1.21.2-1.21.21.1-1.2-1.7-1.41.6-0.0-1.2-1.6-1.3-1.11.6
Bone: cortical porosity0.30.31.0-0.40.3-0.40.30.4-0.2-0.9-0.60.70.5-0.4-1.0-0.4-0.30.7
Bone: cortical thickness1.72.84.8-1.61.7-1.61.81.3-1.4-2.2-1.72.00.4-1.3-2.2-1.5-1.71.8
Bone: cortical thickness0.50.51.9-0.60.7-0.60.80.3-1.4-0.4-0.70.90.1-1.1-0.3-0.4-0.70.8
Bone: cortical tissue density2.02.64.6-1.61.7-1.61.71.7-1.1-2.1-1.81.8-0.2-0.9-2.1-1.4-1.81.6
Bone: elastic displacement0.40.41.5-0.10.1-0.10.10.2-1.1-1.0-0.70.7-0.6-0.4-1.2-0.30.00.7
Bone: elastic work0.40.52.00.2-0.10.2-0.1-0.1-0.8-1.1-0.60.91.3-0.3-1.40.0-0.00.8
Bone: endosteal estimation0.20.41.1-0.60.6-0.60.60.6-0.90.4-0.40.40.5-1.10.7-0.5-0.70.6
Bone: endosteal perimeter0.20.41.5-0.40.4-0.40.40.4-1.10.5-0.40.6-0.2-1.20.8-0.4-0.50.8
Bone: final force1.52.53.6-1.61.6-1.61.71.7-1.9-1.4-1.71.80.9-1.6-1.3-1.5-1.61.7
Bone: final moment1.11.82.8-1.21.3-1.21.31.3-1.7-1.2-1.41.61.6-1.3-1.1-1.1-1.21.4
Bone: marrow area0.20.41.1-0.60.6-0.60.60.6-0.90.4-0.40.40.5-1.00.6-0.5-0.80.6
Bone: maximum diameter1.42.65.5-1.51.6-1.51.61.4-2.3-0.9-1.72.0-0.2-2.3-0.6-1.4-1.62.0
Bone: maximum force1.22.13.0-1.51.5-1.51.61.4-1.7-1.3-1.61.70.9-1.6-1.2-1.3-1.61.6
Bone: maximum moment0.81.43.3-0.91.0-1.01.10.9-1.4-1.0-1.21.41.8-1.2-1.0-0.8-1.21.2
Bone: minimum diameter0.71.33.1-1.21.2-1.21.31.0-1.1-0.8-1.01.21.8-1.2-0.7-0.9-1.31.2
Bone: periosteal estimation1.22.44.1-1.61.6-1.61.71.4-2.0-1.0-1.51.80.5-2.0-0.7-1.4-1.81.8
Bone: periosteal perimeter0.20.31.5-0.30.3-0.30.30.3-0.90.4-0.50.60.3-1.20.6-0.3-0.30.6
Bone: post-yield work0.30.40.9-0.70.8-0.70.80.6-1.0-0.0-0.70.60.0-0.90.2-0.6-0.90.6
Bone: stiffness0.50.71.1-1.01.0-1.01.00.9-0.7-0.7-0.90.90.4-0.7-0.6-0.8-1.10.8
Bone: tissue strength0.40.31.70.7-0.60.6-0.6-0.40.3-0.30.2-0.01.30.6-0.60.50.6-0.1
Bone: trabecular number0.71.12.60.4-0.40.4-0.4-0.61.21.41.2-1.5-1.61.21.50.70.3-1.4
Bone: trabecular spacing0.70.82.5-0.20.3-0.20.30.4-1.6-1.0-1.01.21.3-1.2-1.1-0.3-0.51.3
Bone: trabecular thickness0.20.31.2-0.40.4-0.40.40.20.50.60.2-0.4-1.10.10.9-0.2-0.3-0.5
Bone: trabecular tissue density1.72.33.8-1.41.4-1.41.31.3-0.8-2.0-1.61.9-0.9-1.3-1.9-1.5-1.61.9
Breakpoint value in progressive ratio session1.21.315.2-0.30.2-0.30.01.0-1.00.6-1.0-0.1-3.9-0.70.7-0.40.1-0.1
Distance traveled before self-admin0.20.21.40.10.10.10.2-0.2-1.20.40.10.30.5-0.70.7-0.1-0.30.3
Distance traveled after self-admin1.41.54.4-1.21.2-1.21.21.2-2.1-0.7-1.31.3-0.6-1.5-0.4-1.3-1.31.3
Delta time in closed arm before/after self-admin0.00.00.20.2-0.20.2-0.1-0.1-0.10.40.2-0.1-0.1-0.10.50.10.1-0.1
Delta time in open arm before/after self-admin0.10.10.70.1-0.10.1-0.0-0.4-0.40.60.30.00.5-0.50.80.1-0.00.0
Diff in mean of infusions in LGA sessions0.20.31.1-0.30.4-0.30.5-0.1-0.9-0.10.10.51.1-0.80.2-0.3-0.50.5
Extinction: sum of active levers before priming0.50.51.40.8-0.70.8-0.6-0.90.30.80.8-0.51.20.20.90.70.5-0.5
Active lever presses in extinction session 60.50.51.6-0.60.5-0.60.51.0-1.1-0.1-1.00.4-1.3-0.70.0-0.7-0.40.4
Delta distance traveled before/after self-admin1.31.42.4-1.31.2-1.31.11.6-0.7-1.3-1.51.0-1.2-0.8-1.3-1.2-1.01.0
Delta ambulatory time before/after self-admin0.60.75.8-0.60.4-0.60.31.2-0.0-0.4-1.20.1-2.4-0.1-0.6-0.5-0.10.1
Time in closed arm before self-admin0.30.31.1-0.40.5-0.40.6-0.2-0.8-0.50.00.61.1-0.6-0.4-0.4-0.60.6
Time in closed arm after self-admin0.80.83.00.9-0.80.9-0.6-1.3-0.00.81.3-0.51.70.30.90.80.5-0.5
Time in open arm before self-admin0.40.54.60.1-0.20.1-0.30.70.4-0.2-0.6-0.4-2.10.8-0.50.00.4-0.4
Time in open arm after self-admin0.40.54.50.0-0.20.1-0.30.50.6-0.3-0.5-0.4-2.10.8-0.60.10.4-0.4
Sum of active levers in priming session hrs 5-60.30.31.3-0.50.5-0.50.60.2-0.5-0.3-0.30.61.1-0.8-0.1-0.5-0.60.6
Time to tail flick, vehicle, before self-admin2.22.213.8-1.11.3-1.11.40.4-0.6-1.3-0.51.53.7-1.3-0.9-1.2-1.51.5
Time to tail flick, vehicle, after self-admin1.92.03.01.4-1.51.4-1.6-1.21.31.71.2-1.7-0.31.01.61.51.7-1.7
Time to tail flick, test, before self-admin0.80.85.6-0.50.6-0.50.6-0.00.1-1.2-0.00.72.40.1-1.3-0.4-0.70.7
Time to tail flick, test, after self-admin0.70.76.00.4-0.30.3-0.2-0.81.3-0.10.8-0.12.50.6-0.20.40.1-0.1
Delta time to tail flick, vehicle, before/after SA4.74.617.01.7-2.01.8-2.2-1.01.22.31.0-2.4-4.11.61.91.92.4-2.4
Delta time to tail flick, test, before/after SA0.10.10.70.3-0.30.3-0.3-0.20.80.20.2-0.3-0.20.40.10.30.3-0.3
Ambulatory time before self-admin0.60.63.0-0.20.4-0.20.5-0.2-1.40.30.10.61.7-1.10.8-0.4-0.60.6
Ambulatory time after self-admin1.01.14.1-0.91.0-0.91.00.8-2.0-0.2-0.81.10.1-1.70.3-1.0-1.11.1
Total heroin consumption0.50.61.30.7-0.80.7-0.8-0.60.51.10.6-0.9-0.00.31.10.80.9-0.9
Area under the delay curve0.30.30.6-0.60.6-0.60.50.7-0.4-0.5-0.80.5-0.6-0.4-0.5-0.6-0.50.5
Delay disc. indifference point, 0s delay2.93.24.1-1.92.0-1.92.01.5-1.9-1.6-1.62.00.1-2.0-1.2-1.9-2.02.0
Delay disc. indifference point, 16s delay0.60.60.8-0.90.8-0.90.80.8-0.6-0.9-0.90.8-0.1-0.5-0.9-0.8-0.80.8
Delay disc. indifference point, 2s delay0.60.64.1-0.40.3-0.40.30.5-1.20.6-0.60.3-2.0-1.10.9-0.4-0.30.3
Delay disc. indifference point, 24s delay2.92.87.5-1.61.5-1.61.32.5-1.0-1.3-2.41.2-2.7-1.1-1.3-1.7-1.21.2
Delay disc. indifference point, 4s delay0.10.10.40.2-0.10.2-0.0-0.5-0.30.40.40.00.3-0.30.60.1-0.00.0
Delay disc. indifference point, 8s delay0.10.10.40.2-0.20.2-0.3-0.10.6-0.00.0-0.4-0.30.6-0.30.20.4-0.4
Delay discount exponential model param0.20.20.40.5-0.40.4-0.3-0.60.30.30.7-0.30.60.30.30.40.3-0.3
Delay discount hyperbolic model param0.20.20.70.4-0.40.4-0.3-0.60.50.10.6-0.30.80.50.10.50.3-0.3
Fecal boli incidents, locomotor time 10.50.52.20.6-0.70.6-0.7-0.4-0.00.90.4-0.8-1.50.30.80.70.8-0.8
Change in fecal boli incidents, locomotor task0.40.41.10.7-0.60.7-0.5-1.00.30.60.9-0.40.80.30.70.50.4-0.4
Time >=10cm from walls, locomotor time 13.13.14.21.8-1.91.8-1.9-1.51.62.01.6-1.91.51.32.01.81.9-1.9
Bouts of movement, locomotor time 10.20.32.4-0.10.1-0.10.1-0.50.5-0.50.60.11.60.3-0.60.2-0.10.1
Total resting periods, locomotor time 10.20.21.2-0.20.1-0.20.1-0.30.4-0.70.40.01.10.4-0.90.2-0.00.0
Rest time, locomotor task time 11.21.32.61.3-1.31.3-1.3-1.21.40.31.2-1.20.11.6-0.01.21.2-1.2
Distance moved, locomotor task time 11.01.15.2-0.81.0-0.91.10.5-0.6-0.5-0.51.22.3-1.1-0.1-0.9-1.21.2
Vertical activity count, locomotor time 11.01.01.8-1.01.1-1.01.11.3-0.5-0.6-1.21.11.1-1.1-0.3-1.1-1.11.1
Time >=10cm from walls, locomotor time 21.92.011.21.2-1.11.2-1.0-1.51.50.71.7-1.03.31.20.61.31.0-1.0
Bouts of movement, locomotor time 20.30.41.5-0.60.5-0.60.40.8-0.0-1.0-0.50.4-0.60.1-1.2-0.4-0.40.4
Total resting periods, locomotor time 20.30.31.5-0.50.4-0.50.30.6-0.0-1.0-0.30.2-0.70.3-1.2-0.2-0.20.2
Rest time, locomotor task time 20.70.87.6-0.50.4-0.50.40.5-0.8-0.8-0.90.3-2.8-0.1-1.0-0.6-0.30.3
Distance moved, locomotor task time 20.91.010.9-0.50.6-0.50.70.10.0-0.10.20.83.3-0.90.3-0.4-0.80.8
Vertical activity count, locomotor time 20.91.010.5-0.50.6-0.50.80.40.1-0.4-0.10.93.2-0.7-0.1-0.5-0.90.9
Weight adjusted by age0.30.43.1-0.30.3-0.30.30.5-0.90.1-0.60.3-1.7-0.70.3-0.4-0.30.3
Seeking ratio, delayed vs. immediate footshock0.20.21.00.4-0.30.3-0.2-0.4-0.50.80.5-0.1-0.0-0.41.00.30.2-0.2
Locomotion in novel chamber0.91.23.11.1-1.11.1-1.1-1.11.50.11.0-1.10.51.8-0.41.11.1-1.1
Locomotion in novel chamber post-restriction0.81.02.4-0.91.0-0.91.01.0-1.5-0.4-1.11.1-0.5-1.3-0.1-1.1-1.01.0
Progressive ratio0.91.14.01.0-0.91.0-0.8-1.20.41.11.3-0.72.00.31.21.00.7-0.7
Food seeking constrained by brief footshock0.50.66.0-0.50.3-0.50.20.8-0.1-0.2-0.80.1-2.4-0.1-0.3-0.4-0.10.1
Seeking ratio, punishment vs. effort1.01.39.1-1.00.8-1.00.61.3-0.6-0.6-1.40.5-3.0-0.5-0.7-0.9-0.50.5
Run reversals in cocaine runway, females0.90.88.50.4-0.30.4-0.3-0.61.2-0.40.6-0.22.90.8-0.60.40.3-0.3
Run reversals in cocaine runway, males1.61.57.2-0.81.0-0.81.10.1-1.9-0.30.01.32.7-1.60.2-0.8-1.31.3
Latency to leave start box in cocaine runway3.43.710.2-1.81.7-1.81.72.3-0.6-2.1-2.41.6-3.2-1.0-2.2-2.0-1.61.6
Latency to leave start box in cocaine runway, F2.52.77.0-1.61.6-1.61.61.7-1.3-1.3-1.81.6-2.6-1.6-1.1-1.7-1.61.6
Latency to leave start box in cocaine runway, M1.11.03.3-0.60.5-0.60.41.40.8-1.4-1.40.3-1.80.6-1.8-0.8-0.30.3
Cd content in liver0.50.51.40.6-0.70.6-0.7-0.50.41.10.5-0.9-0.70.31.20.50.7-0.9
Co content in liver0.10.10.30.3-0.30.3-0.3-0.1-0.50.3-0.30.1-0.0-0.40.20.30.10.1
Cu content in liver2.22.63.9-1.91.9-1.91.91.7-0.9-1.9-1.41.3-0.8-0.8-1.8-2.0-1.91.3
Fe content in liver0.50.61.30.9-0.90.9-0.9-0.90.40.40.9-0.80.50.70.30.71.1-0.8
K content in liver2.32.34.6-1.31.4-1.31.51.1-1.7-1.5-1.32.10.9-1.6-1.3-1.2-1.62.1
Mg content in liver0.90.93.5-0.50.5-0.50.60.5-1.9-0.6-0.81.50.1-1.5-0.5-0.4-0.81.5
Mn content in liver0.70.91.5-1.11.1-1.11.11.0-0.8-0.6-0.80.7-1.2-0.8-0.4-0.9-1.00.7
Na content in liver0.50.51.6-0.10.1-0.10.20.1-0.8-1.0-0.71.30.3-0.5-1.30.2-0.31.3
Rb content in liver1.21.52.01.3-1.31.3-1.3-1.21.01.31.4-1.30.51.01.21.11.3-1.3
Se content in liver0.40.41.7-0.50.5-0.50.60.2-0.7-1.0-0.20.51.3-0.1-1.0-0.5-0.80.5
Sr content in liver0.10.00.2-0.10.1-0.10.1-0.0-0.40.2-0.10.1-0.3-0.40.3-0.10.00.1
Zn content in liver0.20.21.2-0.20.3-0.20.4-0.40.8-0.10.6-0.11.10.1-0.0-0.3-0.4-0.1