Hub : Genes

Tle2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000005874 0.02 0.02 5.5e-03 0.01 0.01 0.01 0.01 9.9e-03 1.1e-02 8.5e-03 1.2e-02
2 BLA gene expression ENSRNOG00000005874 0.06 0.05 5.6e-04 0.07 0.06 0.06 0.06 1.6e-04 2.5e-04 3.9e-04 2.8e-04
3 IL gene expression ENSRNOG00000005874 0.35 0.17 1.0e-06 0.16 0.11 0.12 0.13 9.1e-05 1.1e-03 9.1e-04 4.5e-04
4 Liver gene expression ENSRNOG00000005874 0.08 0.07 1.6e-04 0.03 0.03 0.01 0.03 1.8e-04 5.3e-04 9.5e-03 6.6e-04
5 NAcc gene expression ENSRNOG00000005874 0.04 0.03 1.4e-03 0.03 0.03 0.03 0.03 1.6e-03 4.1e-03 2.9e-03 5.5e-03
6 OFC gene expression ENSRNOG00000005874 0.21 0.13 2.1e-04 0.13 0.11 0.12 0.1 5.4e-04 1.8e-03 8.3e-04 2.7e-03
7 PL gene expression ENSRNOG00000005874 0.17 0.1 7.6e-13 0.17 0.16 0.17 0.16 1.1e-12 3.9e-12 9.6e-13 1.4e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail5.818.723.44.8-4.7-4.60.8-4.6-4.6-4.6
BMI without tail2.55.37.32.4-2.7-2.41.0-2.5-2.4-2.4
Body weight1.35.37.02.6-2.6-2.40.6-2.4-2.4-2.4
Epididymis fat weight0.10.10.4-0.50.20.30.70.30.30.2
Glucose1.11.62.11.4-1.4-1.30.4-1.3-1.3-1.3
Heart weight0.30.41.1-1.00.70.40.70.40.40.4
Left kidney weight0.30.71.6-0.50.80.8-1.30.90.80.8
Right kidney weight1.64.66.0-2.42.52.2-0.72.22.22.2
Tail length2.06.08.2-2.92.42.60.52.62.62.7
Length with tail1.55.56.7-2.52.52.5-0.42.62.52.6
Length without tail0.20.51.1-0.30.80.6-1.00.60.60.6
Liver weight, left2.43.94.71.9-2.0-2.20.9-2.2-2.2-2.2
Liver weight, right1.32.22.91.7-1.5-1.60.0-1.6-1.6-1.6
Parametrial fat weight0.20.40.7-0.80.70.60.40.70.60.7
Retroperitoneal fat weight0.82.63.21.7-1.8-1.71.0-1.7-1.7-1.6
Intraocular pressure0.30.42.2-0.2-0.4-0.31.5-0.3-0.3-0.3
Extensor digitorum longus weight4.719.022.54.3-4.6-4.72.1-4.7-4.7-4.7
Soleus weight7.622.227.85.3-5.0-5.00.8-5.0-5.0-5.1
Tibialis anterior weight0.82.63.61.9-1.8-1.70.1-1.7-1.7-1.7
Tibia length0.61.72.7-1.61.41.30.21.31.31.4
Number of licking bursts0.60.71.90.2-0.6-0.81.4-0.8-0.8-0.7
Food consumed during 24 hour testing period0.40.50.60.8-0.8-0.80.2-0.8-0.8-0.7
Times rat made contact with spout0.40.40.80.2-0.5-0.70.9-0.7-0.7-0.6
Mean time between licks in bursts2.73.75.7-2.42.02.00.52.02.02.0
Mean num. licks in bursts0.10.10.3-0.10.30.2-0.50.20.20.2
Std. dev. time between licks in bursts1.41.71.9-1.01.41.3-1.21.31.31.3
Water consumed over 24 hours0.20.31.10.7-0.3-0.3-1.1-0.3-0.3-0.3
Indifference point 0 sec0.10.20.40.6-0.5-0.5-0.1-0.4-0.5-0.5
Indifference point AUC0.91.11.7-1.31.11.1-0.01.11.11.1
Indifference point function ln k0.30.40.50.7-0.6-0.70.3-0.7-0.7-0.7
Indifference point function log k0.30.40.50.7-0.6-0.70.3-0.7-0.7-0.7
Delay discounting total patch changes 0 sec0.10.20.30.6-0.5-0.50.1-0.5-0.5-0.5
Delay discounting total patch changes 12 sec0.50.70.80.6-0.9-0.90.9-0.9-0.9-0.8
Delay discounting total patch changes 18 sec0.70.91.2-1.11.01.0-0.11.01.01.1
Delay discounting total patch changes 24 sec0.10.20.3-0.30.20.5-0.30.40.50.5
Delay discounting total patch changes 6 sec0.10.10.2-0.40.50.40.10.40.40.4
Delay discounting time to switch 0 sec0.81.32.61.6-1.1-1.0-1.0-1.1-1.0-1.1
Delay discounting water rate 0 sec0.30.42.1-0.3-0.3-0.51.5-0.3-0.5-0.4
Delay discounting water rate 12 sec1.82.73.21.2-1.6-1.81.6-1.8-1.8-1.7
Delay discounting water rate 18 sec1.01.36.5-0.2-0.8-0.82.5-0.7-0.8-0.7
Delay discounting water rate 24 sec2.73.79.80.7-1.7-1.93.1-1.8-1.9-1.7
Delay discounting water rate 6 sec0.40.53.3-0.70.0-0.01.8-0.1-0.00.0
Locomotor activity3.86.07.3-2.22.62.7-1.42.72.72.6
Locomotor testing distance2.03.34.1-1.71.82.0-0.92.02.02.0
Locomotor testing rearing0.00.00.1-0.0-0.1-0.10.3-0.0-0.10.0
Light reinforcement 15.09.110.9-3.33.33.2-0.53.23.23.3
Light reinforcement 21.31.82.2-1.41.41.4-0.21.51.41.5
Reaction time number correct1.11.61.80.9-1.3-1.31.3-1.3-1.3-1.3
Reaction time mean minus median0.71.01.6-0.90.81.1-0.51.31.11.1
Reaction time mean minus median AUC0.60.83.0-0.10.50.7-1.70.90.70.7
Reaction time num false alarms0.10.10.20.0-0.1-0.30.4-0.4-0.3-0.2
Reaction time num false alarms AUC0.20.30.70.2-0.5-0.60.8-0.7-0.6-0.5
Reaction time trials correct on left1.11.61.80.9-1.3-1.31.3-1.3-1.3-1.3
Reaction time trials on left1.11.51.70.9-1.2-1.31.2-1.3-1.3-1.3
Reaction time mean0.30.41.70.20.10.4-1.30.60.40.4
Reaction time mean AUC0.20.31.60.30.00.3-1.20.40.30.3
Median of all reaction times0.20.31.50.7-0.3-0.1-1.20.0-0.1-0.1
Reaction time omissions0.20.30.5-0.40.40.6-0.50.70.60.7
Reaction time false alarm rate0.00.00.0-0.00.10.1-0.2-0.00.10.1
Reaction time premature initiation rate0.40.61.2-1.10.80.61.00.60.60.6
Reaction time premature initiations0.40.53.2-0.70.1-0.11.8-0.1-0.1-0.0
Std. dev. reaction times0.50.71.1-0.50.60.8-1.01.00.80.9
Reaction time trials completed1.11.51.70.9-1.2-1.31.2-1.3-1.3-1.3
Reaction time trials AUC1.21.72.20.8-1.3-1.41.5-1.4-1.4-1.3
Social response proportion1.01.11.7-1.21.31.1-0.61.01.11.0
Social responses8.811.413.5-3.53.73.7-1.53.53.73.5
Social time0.91.11.51.1-1.1-1.10.5-1.2-1.1-1.2
Conditioned locomotion2.83.43.81.5-1.9-2.01.6-2.0-2.0-1.9
Cocaine response after cond. corrected6.37.18.62.3-2.7-2.91.8-2.9-2.9-2.9
Cocaine response after cond. not corrected7.17.89.42.4-2.8-3.11.9-3.1-3.1-3.0
Cocaine response before conditioning0.50.70.9-0.60.70.9-0.60.90.90.9
Saline control response0.10.20.30.4-0.6-0.40.5-0.4-0.4-0.3
Condit. Reinf. active minus inactive responses1.31.72.9-1.71.31.20.81.21.21.3
Condit. Reinf. active-inactive response ratio0.40.52.6-0.3-0.3-0.41.6-0.4-0.4-0.3
Condit. Reinf. active responses2.02.73.7-1.91.81.7-0.01.71.71.8
Condit. Reinf. inactive responses1.72.12.4-1.41.51.6-0.91.61.61.6
Condit. Reinf. lever presses1.41.92.7-1.61.21.40.61.41.41.5
Condit. Reinf. lever reinforcers received1.41.93.0-1.71.51.40.31.41.41.5
Pavlov. Cond. lever latency0.81.01.50.9-0.8-1.20.3-1.2-1.2-1.2
Pavlov. Cond. magazine entry latency0.50.60.8-0.60.70.9-0.60.90.90.9
Pavlov. Cond. change in total contacts0.71.01.3-1.11.01.10.01.11.11.1
Pavlov. Cond. index score0.71.01.4-0.90.81.1-0.21.11.11.2
Pavlov. Cond. latency score0.81.01.4-0.90.91.1-0.51.11.11.2
Pavlov. Cond. lever contacts0.50.71.0-0.90.71.00.11.01.01.0
Pavlov. Cond. magazine entry number0.91.11.50.8-0.9-1.20.6-1.2-1.2-1.2
Pavlov. Cond. intertrial magazine entries0.81.01.20.9-1.1-1.10.9-1.1-1.1-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.11.5-0.90.91.2-0.41.21.21.2
Pavlov. Cond. response bias1.31.82.3-1.41.21.50.11.51.51.5
Conditioned reinforcement - actives2.82.83.7-1.91.91.7-0.51.71.71.7
Conditioned reinforcement - inactives1.51.71.91.1-1.3-1.41.3-1.4-1.4-1.3
Conditioned locomotion7.08.411.4-3.43.23.0-0.33.03.03.1
Intermittent access intake day 1-15 change4.54.46.5-2.52.22.20.32.22.22.3
Intermittent access intake escalation3.13.05.2-2.31.61.71.31.71.71.8
Intermittent access intake escalation 24.34.37.2-2.72.02.11.12.12.12.2
Intermitt. access day 1 inactive lever presses0.20.30.7-0.80.40.30.90.30.30.3
Intermitt. access day 15 inactive lever presses0.20.20.6-0.80.60.20.60.20.20.3
Intermitt. access escalation Index0.40.32.00.30.10.2-1.40.20.20.2
Intermittent access day 1 total infusions0.10.10.30.5-0.4-0.3-0.1-0.3-0.3-0.3
Intermittent access day 15 total infusions0.70.81.3-1.10.80.90.70.90.90.9
Intermittent access terminal intake (last 3 days)0.80.81.1-1.00.91.0-0.11.01.01.0
Intermittent access total infusions0.00.00.2-0.20.10.10.40.10.10.1
Intermittent access day 1 locomotion0.10.10.2-0.30.20.20.40.20.20.2
Intermittent access day 15 total locomotion1.92.03.1-1.71.51.50.51.51.51.5
Intermittent access total locomotion0.60.60.8-0.90.80.90.10.90.90.9
Intermittent access standard deviation2.22.34.0-2.01.71.50.41.51.51.6
Cocaine induced anxiety1.72.02.2-1.11.41.5-1.41.51.51.4
Post-drug Anxiety1.92.13.7-0.81.21.5-1.91.51.51.4
Baseline Anxiety0.10.10.3-0.1-0.1-0.20.6-0.2-0.2-0.2
Lifetime Intake0.00.00.0-0.10.00.10.00.10.10.1
Incentive Sensitization - Responses0.30.30.7-0.80.60.40.40.40.40.4
Incentive Sensitization - Breakpoint0.40.40.9-0.90.70.60.10.60.60.6
Progressive ratio test 1 active lever presses0.40.40.60.6-0.7-0.70.5-0.7-0.7-0.6
Progressive ratio test 1 breakpoint0.40.40.60.7-0.8-0.70.4-0.7-0.7-0.6
Progressive ratio test 1 inactive lever presses0.00.00.00.00.00.00.00.00.00.0
Progressive ratio test 2 active lever presses0.10.10.3-0.50.30.20.50.20.20.2
Progressive ratio test 2 breakpoint0.30.30.6-0.70.70.6-0.10.60.60.6
Progressive ratio test 2 inactive lever presses0.10.10.1-0.30.40.2-0.20.20.20.2
Total sessions with >9 infusions0.30.31.2-0.10.40.5-1.10.50.50.5
Short access day 1 total inactive lever presses0.00.00.0-0.0-0.00.10.00.10.10.1
Short access day 10 total inactive lever presses0.10.10.7-0.1-0.1-0.20.8-0.2-0.2-0.1
Short access day 1 total infusions0.40.51.3-0.00.30.7-1.10.70.70.7
Short access day 10 total infusions0.00.00.00.1-0.1-0.0-0.1-0.0-0.00.0
Short access total infusions0.10.10.60.10.00.3-0.80.30.30.3
Short access day 1 locomotion0.70.70.9-0.70.90.9-0.50.90.90.9
Short access day 10 total locomotion2.62.84.6-2.21.81.70.51.71.71.7
Short access total locomotion0.70.71.0-0.80.81.0-0.31.01.01.0
Compulsive drug intake0.50.51.01.0-0.8-0.7-0.2-0.7-0.7-0.8
One hour access (0.3 mA shock)0.30.40.40.6-0.6-0.70.3-0.7-0.7-0.7
One hour access (shock baseline)0.10.10.6-0.0-0.1-0.30.7-0.3-0.3-0.2
Number of responses in last shaping day0.10.10.2-0.30.30.4-0.20.40.40.4
Context. condit. distance diff. score0.30.40.50.6-0.6-0.70.2-0.7-0.7-0.7
Locomotion velocity, session 11.61.72.0-1.01.41.3-1.41.31.31.3
Locomotion distance, session 11.01.23.4-0.51.01.0-1.81.01.00.9
Locomotion velocity, session 25.46.37.1-2.22.72.7-2.12.72.72.6
Locomotion distance, session 23.04.34.9-1.62.22.1-2.12.12.12.1
Locomotion velocity, session 35.05.87.9-2.82.62.5-0.22.52.52.6
Locomotion distance, session 30.00.00.1-0.20.10.00.20.00.00.0
Stereotopy head waving bouts, day 34.55.46.3-2.42.52.5-1.02.52.52.5
Stereotopy head waving duration, day 34.96.06.9-2.62.62.6-0.82.62.62.6
Locomotion velocity, session 71.01.11.4-1.11.21.1-0.61.11.11.1
Locomotion distance, session 70.20.30.80.1-0.4-0.50.9-0.5-0.5-0.5
Stereotopy head waving bouts, day 70.40.52.0-0.00.50.5-1.40.50.50.5
Stereotopy head waving duration, day 70.81.02.7-0.40.90.9-1.70.90.90.9
Locomotion velocity, session 81.72.04.1-0.81.41.4-2.01.41.41.3
Locomotion distance, session 80.20.30.5-0.40.70.6-0.70.60.60.5
Degree of sensitization distance0.30.30.50.7-0.7-0.60.0-0.6-0.6-0.6
Degree of sensitization stereotypy1.01.02.01.4-1.0-0.9-1.0-0.9-0.9-0.9
Condit. Reinf. active minus inactive responses3.84.25.5-2.32.32.2-0.42.22.22.2
Condit. Reinf. active-inactive response ratio1.41.52.5-1.61.31.20.51.21.21.2
Condit. Reinf. active responses4.35.26.5-2.32.52.4-1.32.42.42.4
Condit. Reinf. inactive responses1.72.02.3-1.11.51.5-1.51.51.51.4
Incentive salience index mean2.83.44.3-1.82.11.9-1.11.91.91.9
Condit. Reinf. lever presses0.91.24.1-0.41.00.9-2.00.90.90.8
Time in familiar zone, hab. session 11.51.42.1-1.51.21.20.31.21.21.2
Time in novel zone, hab. session 10.50.51.30.9-0.4-0.5-1.2-0.5-0.5-0.5
Total zone transitions, hab. session 11.82.52.8-1.21.71.6-1.61.61.61.6
Total locomotion distance, hab. session 13.04.36.4-1.42.22.1-2.52.12.12.0
Locomotion velocity, hab. session 13.04.34.9-1.72.22.1-2.12.12.12.1
Time in familiar zone, hab. session 24.04.16.6-2.62.12.10.82.12.12.1
Time in novel zone, hab. session 22.62.64.52.1-1.6-1.6-1.0-1.6-1.6-1.7
Total zone transitions, hab. session 20.50.63.30.20.40.4-1.80.40.40.3
Total locomotion distance, hab. session 21.72.32.7-1.31.61.6-1.41.61.61.5
Locomotion velocity, hab. session 22.02.63.2-1.21.71.7-1.81.71.71.6
Novel to familiar place preference ratio2.02.13.92.0-1.4-1.3-1.3-1.3-1.3-1.4
Novelty place preference1.11.12.21.5-0.9-0.9-1.3-0.9-0.9-0.9
Time in novel zone, NPP test1.31.42.61.6-1.1-1.0-1.2-1.0-1.0-1.1
Total zone transitions, NPP test0.10.20.9-0.10.40.3-0.90.30.30.3
Total locomotion distance, NPP test0.30.41.9-0.10.60.5-1.40.50.50.4
Locomotion velocity, NPP test0.50.71.8-0.40.80.7-1.30.70.70.6
Pavlov. Cond. lever latency0.30.41.80.1-0.5-0.51.3-0.5-0.5-0.4
Pavlov. Cond. magazine entry latency2.02.53.7-1.91.71.70.11.71.71.7
Pavlov. Cond. change in total contacts0.10.10.1-0.30.40.3-0.20.30.30.3
Pavlov. Cond. index score0.70.91.0-0.81.01.0-0.91.01.00.9
Pavlov. Cond. latency score0.91.21.7-0.71.11.1-1.31.11.11.0
Pavlov. Cond. lever contacts0.80.92.6-0.40.90.8-1.60.80.80.8
Pavlov. Cond. magazine entry number0.50.60.80.9-0.9-0.80.1-0.8-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.9-0.2-0.2-0.11.0-0.1-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.01.31.6-1.11.31.2-0.91.21.21.2
Pavlov. Cond. response bias0.91.21.4-1.21.21.1-0.31.11.11.1
Bone: apparent density1.22.07.0-0.31.21.2-2.61.21.21.1
Bone surface3.25.715.1-0.92.22.2-3.92.22.22.0
Bone volume3.45.715.1-0.92.22.2-3.92.22.22.0
Bone: connectivity density0.50.83.90.10.60.6-2.00.60.60.4
Bone: cortical apparent density1.21.52.11.4-1.4-1.30.2-1.3-1.3-1.2
Bone: cortical area0.30.42.00.8-0.2-0.2-1.4-0.2-0.2-0.3
Bone: cortical porosity0.80.91.1-0.91.11.0-0.81.01.01.0
Bone: cortical porosity0.40.51.3-0.30.70.6-1.20.60.60.5
Bone: cortical thickness0.71.11.91.4-1.0-1.0-0.6-1.0-1.0-1.1
Bone: cortical thickness0.10.20.7-0.0-0.3-0.30.8-0.3-0.3-0.2
Bone: cortical tissue density0.91.21.61.3-1.2-1.10.2-1.1-1.1-1.1
Bone: elastic displacement0.30.30.4-0.60.60.6-0.20.60.60.6
Bone: elastic work0.10.10.30.4-0.2-0.2-0.6-0.2-0.2-0.2
Bone: endosteal estimation0.10.20.60.6-0.2-0.3-0.8-0.3-0.3-0.3
Bone: endosteal perimeter0.61.32.0-0.81.21.2-1.41.21.21.1
Bone: final force0.50.81.51.2-0.7-0.7-1.2-0.7-0.7-0.8
Bone: final moment0.40.61.31.1-0.6-0.6-1.1-0.6-0.6-0.7
Bone: marrow area0.10.20.60.6-0.3-0.3-0.7-0.3-0.3-0.4
Bone: maximum diameter1.32.43.1-1.01.61.6-1.81.61.61.5
Bone: maximum force0.61.01.91.4-0.9-0.9-0.9-0.9-0.9-1.0
Bone: maximum moment0.50.81.51.2-0.8-0.8-0.9-0.8-0.8-0.9
Bone: minimum diameter0.10.31.30.00.40.4-1.10.40.40.3
Bone: periosteal estimation0.20.42.50.7-0.1-0.1-1.6-0.1-0.1-0.2
Bone: periosteal perimeter0.61.02.9-0.30.90.9-1.70.90.90.8
Bone: post-yield work0.60.81.01.0-0.9-1.00.1-1.0-1.0-0.9
Bone: stiffness1.82.84.42.1-1.7-1.7-0.5-1.7-1.7-1.8
Bone: tissue strength1.41.42.11.4-1.2-1.2-0.2-1.2-1.2-1.3
Bone: trabecular number2.03.23.6-1.31.81.9-1.91.91.91.8
Bone: trabecular spacing2.53.26.80.9-1.7-1.72.6-1.7-1.7-1.6
Bone: trabecular thickness2.93.611.9-0.51.71.6-3.51.61.61.4
Bone: trabecular tissue density3.54.95.72.1-2.4-2.41.4-2.4-2.4-2.3
Breakpoint value in progressive ratio session3.13.45.1-2.31.82.00.41.92.02.0
Distance traveled before self-admin0.10.10.20.5-0.3-0.3-0.4-0.2-0.3-0.2
Distance traveled after self-admin1.11.21.5-1.11.11.2-0.41.21.21.2
Delta time in closed arm before/after self-admin2.42.34.90.8-1.5-1.52.2-1.5-1.5-1.4
Delta time in open arm before/after self-admin1.00.91.31.1-0.9-1.1-0.2-1.0-1.1-1.0
Diff in mean of infusions in LGA sessions1.21.31.8-1.41.21.2-0.01.21.21.2
Extinction: sum of active levers before priming0.60.61.4-1.20.70.51.10.50.50.6
Active lever presses in extinction session 63.13.04.0-2.02.01.8-0.51.81.81.8
Delta distance traveled before/after self-admin1.41.51.8-1.31.21.4-0.21.41.41.3
Delta ambulatory time before/after self-admin2.02.22.6-1.51.51.6-0.71.61.61.6
Time in closed arm before self-admin0.50.51.31.1-0.7-0.4-1.1-0.4-0.4-0.5
Time in closed arm after self-admin0.00.00.00.1-0.20.20.10.20.20.2
Time in open arm before self-admin1.01.12.0-1.41.21.00.30.91.00.9
Time in open arm after self-admin0.90.91.40.7-0.7-1.20.5-1.2-1.2-1.1
Sum of active levers in priming session hrs 5-60.00.00.10.2-0.3-0.20.2-0.2-0.2-0.1
Time to tail flick, vehicle, before self-admin1.61.72.7-0.60.91.4-1.71.41.41.4
Time to tail flick, vehicle, after self-admin0.20.20.9-0.60.2-0.10.9-0.1-0.1-0.0
Time to tail flick, test, before self-admin1.11.12.6-0.61.01.0-1.60.91.00.9
Time to tail flick, test, after self-admin0.60.61.1-0.40.60.8-1.10.80.80.8
Delta time to tail flick, vehicle, before/after SA1.61.53.10.4-0.9-1.31.8-1.3-1.3-1.3
Delta time to tail flick, test, before/after SA0.20.10.9-0.1-0.3-0.11.0-0.1-0.1-0.1
Ambulatory time before self-admin0.10.10.20.5-0.4-0.4-0.2-0.3-0.4-0.3
Ambulatory time after self-admin0.60.60.8-0.80.80.8-0.30.90.80.9
Total heroin consumption1.82.22.6-1.61.51.6-0.51.61.61.6
Area under the delay curve1.41.52.51.6-1.3-1.2-0.4-1.2-1.2-1.2
Delay disc. indifference point, 0s delay3.94.37.82.8-2.0-2.0-1.6-2.0-2.0-2.0
Delay disc. indifference point, 16s delay0.10.10.20.5-0.4-0.3-0.2-0.3-0.3-0.3
Delay disc. indifference point, 2s delay3.94.47.82.8-2.3-2.0-0.8-2.0-2.0-2.1
Delay disc. indifference point, 24s delay0.30.30.40.6-0.6-0.60.2-0.6-0.6-0.6
Delay disc. indifference point, 4s delay0.50.51.11.0-0.6-0.5-1.1-0.5-0.5-0.6
Delay disc. indifference point, 8s delay1.21.21.51.0-1.1-1.20.6-1.2-1.2-1.2
Delay discount exponential model param1.31.32.3-1.51.31.20.31.21.21.2
Delay discount hyperbolic model param1.92.03.4-1.81.61.40.41.41.41.4
Fecal boli incidents, locomotor time 12.52.73.51.5-1.8-1.91.0-1.6-1.9-1.6
Change in fecal boli incidents, locomotor task1.21.12.1-0.61.11.1-1.41.01.10.9
Time >=10cm from walls, locomotor time 10.20.20.90.5-0.1-0.3-1.0-0.1-0.3-0.2
Bouts of movement, locomotor time 10.10.10.3-0.50.40.20.20.40.20.4
Total resting periods, locomotor time 10.20.20.3-0.50.50.4-0.10.60.40.5
Rest time, locomotor task time 10.20.20.3-0.40.50.4-0.30.60.40.6
Distance moved, locomotor task time 10.20.21.00.6-0.2-0.0-1.0-0.2-0.0-0.3
Vertical activity count, locomotor time 10.10.10.20.2-0.3-0.20.4-0.3-0.2-0.3
Time >=10cm from walls, locomotor time 21.41.52.01.2-1.3-1.20.8-1.4-1.2-1.3
Bouts of movement, locomotor time 21.01.11.6-0.91.30.9-1.21.10.91.0
Total resting periods, locomotor time 21.11.21.8-0.91.30.9-1.31.10.91.0
Rest time, locomotor task time 20.81.01.4-0.81.01.0-0.91.21.01.1
Distance moved, locomotor task time 21.21.41.91.0-1.1-1.21.0-1.4-1.2-1.3
Vertical activity count, locomotor time 21.71.92.41.0-1.3-1.41.6-1.5-1.4-1.4
Weight adjusted by age0.50.50.80.2-0.5-0.90.8-0.8-0.9-0.7
Seeking ratio, delayed vs. immediate footshock5.15.97.5-2.32.32.7-0.92.72.72.7
Locomotion in novel chamber0.40.61.0-1.00.70.70.40.90.70.7
Locomotion in novel chamber post-restriction0.50.60.9-0.80.70.8-0.20.80.80.9
Progressive ratio0.20.20.3-0.1-0.1-0.50.6-0.6-0.5-0.5
Food seeking constrained by brief footshock0.10.20.3-0.50.50.4-0.10.40.40.3
Seeking ratio, punishment vs. effort0.10.10.20.10.00.3-0.30.40.30.3
Run reversals in cocaine runway, females1.71.72.2-1.31.51.4-1.01.31.41.2
Run reversals in cocaine runway, males1.61.62.0-1.01.11.4-0.91.41.41.4
Latency to leave start box in cocaine runway1.92.02.7-0.91.31.5-1.51.61.51.6
Latency to leave start box in cocaine runway, F1.01.14.70.00.60.8-2.20.90.80.8
Latency to leave start box in cocaine runway, M1.91.83.4-1.81.41.21.01.21.21.3
Cd content in liver0.20.20.40.6-0.6-0.3-0.1-0.3-0.3-0.4
Co content in liver0.30.40.6-0.80.60.60.50.50.60.5
Cu content in liver0.20.21.30.10.30.2-1.20.20.20.2
Fe content in liver0.10.10.5-0.2-0.0-0.20.7-0.2-0.2-0.2
K content in liver0.40.41.3-0.30.70.5-1.10.50.50.4
Mg content in liver0.60.62.1-0.30.80.6-1.40.60.60.5
Mn content in liver3.64.26.9-1.42.22.0-2.62.02.01.9
Na content in liver0.50.50.80.9-0.6-0.7-0.6-0.7-0.7-0.7
Rb content in liver0.30.42.00.7-0.2-0.0-1.40.0-0.0-0.1
Se content in liver0.30.40.6-0.70.80.6-0.30.50.60.6
Sr content in liver0.40.41.8-0.0-0.4-0.41.3-0.5-0.4-0.4
Zn content in liver1.11.23.0-1.60.90.71.70.60.70.7