Hub : Genes

Aco1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000008337 0.52 0.17 3.4e-04 -0 0 0.02 0 6.5e-01 1.1e-01 3.3e-03 1.1e-01
2 Adipose alternative polyA ENSRNOT00000100040 0.47 0.18 3.4e-04 0 0 0.01 0 2.1e-01 8.7e-02 1.0e-02 7.2e-02
3 Adipose mRNA stability ENSRNOG00000005849 0.12 0.06 4.0e-10 0.09 0.09 0.09 0.09 4.1e-10 2.4e-10 7.6e-10 5.3e-10
4 BLA gene expression ENSRNOG00000005849 0.33 0.12 6.8e-14 0.27 0.24 0.24 0.24 8.4e-15 4.9e-13 4.5e-13 2.2e-13
5 BLA mRNA stability ENSRNOG00000005849 0.21 0.16 1.9e-03 0.03 0.05 0.04 0.06 6.1e-03 1.4e-03 2.2e-03 4.9e-04
6 Brain gene expression ENSRNOG00000005849 0.24 0.1 7.8e-16 0.18 0.17 0.15 0.18 7.5e-17 1.4e-15 3.9e-14 3.5e-16
7 Brain mRNA stability ENSRNOG00000005849 0.2 0.1 1.6e-13 0.17 0.13 0.16 0.16 3.2e-15 3.0e-12 2.4e-14 2.0e-14
8 LHb gene expression ENSRNOG00000005849 0.21 0.11 1.3e-04 0.05 0.08 0.07 0.07 2.8e-02 6.5e-03 1.0e-02 1.1e-02
9 Liver alternative polyA ENSRNOT00000008337 0.02 0.01 9.6e-03 0.01 0.02 -0 0.02 1.4e-02 6.0e-03 6.2e-01 3.8e-03
10 Liver alternative polyA ENSRNOT00000100040 0.02 0.02 8.5e-03 0.02 0.02 -0 0.02 1.9e-03 3.5e-03 4.5e-01 9.6e-04
11 NAcc gene expression ENSRNOG00000005849 0.31 0.11 3.3e-16 0.24 0.22 0.21 0.22 1.5e-17 5.5e-16 7.6e-16 1.3e-16
12 NAcc mRNA stability ENSRNOG00000005849 0.14 0.08 6.6e-09 0.11 0.1 0.1 0.11 1.8e-08 5.5e-08 9.8e-08 9.8e-09
13 OFC isoform ratio ENSRNOT00000008337 0.15 0.1 4.6e-03 0.11 0.04 0.04 0.08 1.4e-03 4.1e-02 3.5e-02 5.1e-03
14 OFC isoform ratio ENSRNOT00000100040 0.15 0.1 3.5e-03 0.11 0.04 0.07 0.08 1.4e-03 4.2e-02 1.0e-02 5.2e-03
15 PL gene expression ENSRNOG00000005849 0.04 0.03 8.6e-04 0.04 0.02 0.02 0.02 9.2e-04 2.0e-02 1.2e-02 1.1e-02
16 PL mRNA stability ENSRNOG00000005849 0.17 0.11 1.5e-08 0.13 0.1 0.12 0.12 2.6e-10 3.1e-08 9.5e-10 1.9e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
BMI with tail1.24.06.7-1.41.42.01.92.02.21.92.5-1.92.61.92.2-2.02.01.91.9
BMI without tail1.94.08.5-0.60.71.91.81.71.81.72.9-1.82.11.61.9-2.72.72.91.5
Body weight1.87.613.6-1.51.72.22.52.62.82.43.7-2.53.72.52.8-3.23.23.42.5
Epididymis fat weight0.40.92.5-0.60.40.40.50.70.60.51.3-0.51.40.60.9-1.61.61.30.6
Glucose0.91.42.8-0.00.30.41.31.31.41.31.2-1.21.71.41.2-1.11.11.11.3
Heart weight1.52.14.1-0.20.21.31.71.71.41.61.7-1.62.01.41.5-1.61.60.91.4
Left kidney weight0.41.36.30.9-0.30.50.60.50.20.51.6-0.62.50.30.4-1.71.71.50.3
Right kidney weight0.41.15.02.2-1.80.70.50.50.10.41.3-0.52.20.30.2-0.70.70.50.2
Tail length0.92.87.6-0.50.71.41.41.31.41.42.4-1.41.61.21.5-2.32.32.81.2
Length with tail0.31.24.3-0.40.90.20.50.60.70.51.6-0.51.50.50.7-1.81.82.10.5
Length without tail0.20.41.6-0.20.5-1.3-0.9-0.6-0.5-0.9-0.60.90.3-0.5-0.60.3-0.3-0.6-0.5
Liver weight, left0.91.42.6-0.80.61.11.11.21.11.11.5-1.11.11.21.3-1.61.61.11.2
Liver weight, right0.20.33.21.2-1.8-0.1-0.00.0-0.1-0.0-0.10.00.1-0.0-0.20.0-0.0-0.00.0
Parametrial fat weight0.20.40.9-0.70.7-0.9-0.6-0.7-0.5-0.6-0.00.60.1-0.6-0.3-0.90.90.4-0.5
Retroperitoneal fat weight0.10.41.10.6-1.0-0.2-0.6-0.6-0.7-0.7-0.50.6-0.3-0.7-0.50.5-0.5-0.7-0.7
Intraocular pressure0.81.12.4-0.81.20.80.71.00.80.81.4-0.81.40.81.0-1.21.21.50.9
Extensor digitorum longus weight5.321.428.1-2.63.13.84.85.04.94.85.3-4.95.24.94.9-4.64.64.84.9
Soleus weight0.41.06.32.5-1.7-0.9-0.9-0.7-0.9-1.0-0.31.0-0.2-0.9-1.0-0.00.00.1-0.8
Tibialis anterior weight5.518.928.8-2.73.53.54.14.34.24.15.3-4.24.74.24.4-5.15.15.44.2
Tibia length0.20.50.90.70.10.10.70.70.70.70.8-0.70.90.70.5-0.90.90.70.7
Number of licking bursts5.96.99.4-2.42.02.52.62.62.62.53.1-2.52.42.62.9-3.03.02.82.6
Food consumed during 24 hour testing period1.92.34.90.10.40.41.81.81.71.71.5-1.72.21.81.6-1.51.51.31.8
Times rat made contact with spout0.30.41.7-1.30.70.60.40.30.40.30.6-0.30.20.40.6-0.70.70.80.4
Mean time between licks in bursts0.50.73.71.8-1.9-0.3-0.4-0.4-0.4-0.3-0.50.3-0.3-0.4-0.60.7-0.7-0.9-0.4
Mean num. licks in bursts3.03.75.31.2-1.3-1.7-1.9-1.9-1.9-1.9-2.31.9-1.8-1.9-2.02.3-2.3-2.0-1.9
Std. dev. time between licks in bursts0.70.82.91.3-1.70.0-0.8-0.8-0.8-0.7-0.70.7-0.7-0.8-0.91.2-1.2-0.6-0.8
Water consumed over 24 hours1.41.62.6-0.70.51.01.31.31.21.11.6-1.11.21.31.4-1.61.61.51.3
Indifference point 0 sec0.50.92.60.50.6-1.6-1.1-1.0-0.9-1.0-0.31.1-0.4-0.9-0.8-0.90.91.1-0.9
Indifference point AUC4.65.49.2-1.31.41.32.52.52.22.52.5-2.53.02.42.4-2.32.32.72.4
Indifference point function ln k1.52.12.61.1-1.1-1.1-1.5-1.6-1.4-1.3-1.61.3-1.6-1.5-1.61.4-1.4-1.6-1.6
Indifference point function log k1.52.12.61.1-1.1-1.1-1.5-1.6-1.4-1.3-1.61.3-1.6-1.5-1.61.4-1.4-1.6-1.6
Delay discounting total patch changes 0 sec0.50.72.3-0.11.0-1.2-0.7-0.7-0.5-0.70.20.8-0.1-0.6-0.4-1.41.41.5-0.6
Delay discounting total patch changes 12 sec1.21.63.1-0.70.90.61.31.41.41.21.3-1.21.81.51.3-1.01.01.61.4
Delay discounting total patch changes 18 sec0.20.31.01.0-0.90.10.40.60.20.30.4-0.30.60.40.3-0.40.40.90.5
Delay discounting total patch changes 24 sec0.81.03.0-0.40.80.60.91.00.50.81.4-0.71.20.70.7-1.41.41.70.8
Delay discounting total patch changes 6 sec1.01.54.6-0.30.9-0.01.11.10.90.91.3-0.81.51.01.0-1.91.92.11.0
Delay discounting time to switch 0 sec1.01.54.10.7-1.1-0.4-0.7-0.7-0.8-0.8-1.70.8-1.4-0.9-1.02.0-2.0-2.0-0.8
Delay discounting water rate 0 sec0.40.72.8-0.51.1-0.40.00.10.20.20.9-0.10.70.30.4-1.51.51.70.1
Delay discounting water rate 12 sec0.10.10.3-0.10.6-0.3-0.2-0.3-0.3-0.20.20.2-0.1-0.2-0.2-0.50.50.4-0.2
Delay discounting water rate 18 sec0.60.71.5-1.11.01.20.70.81.00.71.1-0.70.60.80.9-0.70.70.50.7
Delay discounting water rate 24 sec0.10.10.6-0.80.50.8-0.10.00.2-0.10.40.1-0.40.10.3-0.30.3-0.20.0
Delay discounting water rate 6 sec0.81.22.8-1.21.00.80.90.80.80.91.4-0.80.30.91.1-1.71.71.40.8
Locomotor activity0.00.00.2-0.00.1-0.30.10.0-0.1-0.2-0.10.20.4-0.0-0.10.1-0.10.1-0.1
Locomotor testing distance0.10.10.70.5-0.2-0.80.0-0.00.1-0.1-0.20.20.5-0.1-0.1-0.30.30.1-0.2
Locomotor testing rearing0.60.91.9-0.40.7-0.21.01.01.11.00.8-0.91.31.00.9-1.11.11.40.9
Light reinforcement 11.32.47.30.40.8-0.61.61.61.41.61.2-1.62.71.51.2-1.41.42.41.6
Light reinforcement 20.40.51.70.40.7-1.2-0.1-0.00.1-0.00.4-0.11.20.1-0.0-1.11.11.30.0
Reaction time number correct0.10.21.21.1-0.8-0.5-0.2-0.3-0.3-0.3-0.30.3-0.6-0.3-0.40.2-0.20.0-0.3
Reaction time mean minus median1.72.35.5-0.5-0.12.31.81.91.81.81.2-1.81.22.01.60.5-0.50.11.9
Reaction time mean minus median AUC2.53.25.6-0.5-0.02.42.22.32.22.21.6-2.11.62.42.0-0.20.20.82.3
Reaction time num false alarms0.30.41.50.1-0.91.20.70.70.60.60.7-0.60.50.60.8-0.20.20.10.6
Reaction time num false alarms AUC0.60.81.70.0-0.61.30.91.00.90.81.2-0.81.00.91.2-0.80.80.80.9
Reaction time trials correct on left0.10.21.21.1-0.8-0.5-0.2-0.3-0.3-0.3-0.30.3-0.6-0.3-0.40.2-0.20.0-0.3
Reaction time trials on left0.20.31.51.2-1.0-0.5-0.3-0.4-0.4-0.4-0.40.4-0.7-0.4-0.50.3-0.3-0.1-0.4
Reaction time mean0.81.13.21.0-1.51.4-0.4-0.20.0-0.5-0.50.4-1.00.0-0.31.8-1.8-1.8-0.0
Reaction time mean AUC0.91.23.61.1-1.71.4-0.5-0.3-0.0-0.5-0.60.5-1.1-0.1-0.31.9-1.9-1.8-0.1
Median of all reaction times1.72.45.31.7-2.00.6-1.4-1.2-0.9-1.5-1.21.3-1.8-1.0-1.22.1-2.1-2.3-1.0
Reaction time omissions1.41.811.22.7-3.40.3-0.5-0.4-0.6-0.6-0.70.5-0.2-0.7-0.91.5-1.5-1.4-0.7
Reaction time false alarm rate0.20.21.2-0.4-0.41.10.30.50.30.30.6-0.30.60.30.7-0.30.30.10.3
Reaction time premature initiation rate2.02.88.11.2-0.8-1.2-1.3-1.3-1.1-1.3-2.21.3-1.4-1.2-1.62.8-2.8-2.0-1.3
Reaction time premature initiations1.92.76.81.6-1.1-1.4-1.3-1.3-1.1-1.3-2.11.3-1.5-1.2-1.62.6-2.6-1.8-1.2
Std. dev. reaction times0.50.73.1-0.0-0.51.80.60.80.90.50.2-0.5-0.00.90.61.3-1.3-0.80.8
Reaction time trials completed0.20.31.51.2-1.0-0.5-0.3-0.4-0.4-0.4-0.40.4-0.7-0.4-0.50.3-0.3-0.1-0.4
Reaction time trials AUC0.20.31.11.1-0.8-0.5-0.3-0.4-0.4-0.4-0.40.4-0.7-0.4-0.50.3-0.3-0.2-0.4
Social response proportion1.21.34.3-0.40.3-1.2-1.1-1.3-0.9-1.1-1.31.1-0.7-1.1-1.11.0-1.0-2.1-1.1
Social responses0.50.72.4-0.60.9-0.30.80.70.80.80.6-0.81.50.90.7-0.50.50.80.9
Social time0.40.64.02.0-1.9-0.1-0.00.0-0.3-0.0-0.20.00.4-0.0-0.30.7-0.7-0.20.1
Conditioned locomotion0.60.72.40.6-0.4-1.6-0.9-1.0-0.9-0.9-0.80.9-0.8-0.9-0.90.1-0.10.2-0.9
Cocaine response after cond. corrected1.82.03.21.2-0.9-1.6-1.7-1.6-1.6-1.7-1.21.8-1.1-1.7-1.60.7-0.7-0.7-1.7
Cocaine response after cond. not corrected1.51.73.11.1-0.9-1.4-1.7-1.6-1.5-1.7-0.91.8-0.9-1.6-1.50.3-0.3-0.4-1.6
Cocaine response before conditioning1.21.52.3-1.00.71.21.21.21.31.11.5-1.21.31.31.3-1.41.41.21.2
Saline control response0.91.33.3-0.20.80.90.70.80.80.71.6-0.81.20.70.8-1.81.81.80.7
Condit. Reinf. active minus inactive responses1.01.32.3-0.30.40.81.41.31.31.51.1-1.41.51.31.1-0.70.70.81.3
Condit. Reinf. active-inactive response ratio0.10.10.2-0.30.50.30.40.30.30.50.2-0.50.30.30.20.0-0.0-0.10.3
Condit. Reinf. active responses2.23.15.1-0.50.81.42.02.01.92.11.9-2.02.31.91.8-1.51.51.71.9
Condit. Reinf. inactive responses3.84.76.6-0.80.42.22.42.52.52.42.4-2.42.62.52.4-1.71.72.02.5
Condit. Reinf. lever presses2.94.06.2-0.70.62.42.32.42.32.42.2-2.32.52.32.1-0.90.91.72.3
Condit. Reinf. lever reinforcers received2.73.76.2-0.60.91.52.22.22.12.32.1-2.22.52.22.0-1.51.51.92.1
Pavlov. Cond. lever latency2.73.65.71.1-0.9-2.4-2.1-2.2-2.1-2.1-2.22.1-2.2-2.2-2.01.1-1.1-1.8-2.1
Pavlov. Cond. magazine entry latency0.20.21.20.7-1.10.7-0.2-0.0-0.1-0.2-0.10.2-0.2-0.1-0.20.8-0.8-0.6-0.1
Pavlov. Cond. change in total contacts1.11.53.9-0.70.42.01.41.51.41.51.2-1.51.41.41.3-0.00.00.51.4
Pavlov. Cond. index score0.40.62.4-0.2-0.21.60.70.90.80.80.8-0.80.90.80.70.2-0.20.20.8
Pavlov. Cond. latency score0.70.83.0-0.40.11.71.01.11.01.01.0-1.01.11.00.90.1-0.10.41.0
Pavlov. Cond. lever contacts1.41.93.6-0.60.31.91.51.61.61.61.6-1.51.71.61.4-0.70.71.21.6
Pavlov. Cond. magazine entry number0.20.21.90.40.1-1.4-0.3-0.5-0.4-0.4-0.40.4-0.3-0.4-0.4-0.30.30.1-0.4
Pavlov. Cond. intertrial magazine entries0.40.50.7-0.40.6-0.20.80.70.60.80.6-0.80.70.70.7-0.80.80.80.7
Pavlov. Cond. lever-magazine prob. diff.0.40.52.7-0.1-0.21.60.70.90.80.70.8-0.70.80.80.70.3-0.30.20.8
Pavlov. Cond. response bias0.60.82.9-0.40.11.70.91.00.90.91.1-0.91.01.00.9-0.20.20.61.0
Conditioned reinforcement - actives0.30.30.9-0.20.40.80.60.50.60.70.6-0.70.50.60.30.1-0.10.90.5
Conditioned reinforcement - inactives0.70.81.7-0.40.5-0.41.01.00.91.30.2-1.31.21.20.8-0.20.20.91.1
Conditioned locomotion0.20.21.7-1.01.3-0.4-0.0-0.0-0.30.2-0.2-0.2-0.30.1-0.1-0.00.00.80.1
Intermittent access intake day 1-15 change1.41.43.30.9-1.21.81.81.41.01.70.8-1.70.71.10.90.4-0.40.41.2
Intermittent access intake escalation1.51.53.41.0-1.21.21.91.51.11.70.6-1.71.01.21.00.2-0.20.71.4
Intermittent access intake escalation 21.71.73.5-0.1-0.41.71.91.71.21.81.0-1.80.91.51.4-0.20.20.91.6
Intermitt. access day 1 inactive lever presses0.60.75.0-1.92.2-1.0-0.3-0.1-0.30.1-0.1-0.10.2-0.20.0-0.50.50.7-0.2
Intermitt. access day 15 inactive lever presses0.20.31.3-0.71.2-0.60.30.20.30.7-0.0-0.70.30.20.1-0.40.40.50.2
Intermitt. access escalation Index0.40.31.1-0.50.6-0.00.40.40.60.40.4-0.40.10.30.5-1.11.11.00.3
Intermittent access day 1 total infusions1.51.63.10.9-0.8-1.3-1.8-1.7-1.3-1.3-1.41.3-1.3-1.4-1.40.8-0.8-0.6-1.6
Intermittent access day 15 total infusions0.20.30.60.8-0.80.10.60.40.30.8-0.2-0.80.20.40.20.4-0.40.50.4
Intermittent access terminal intake (last 3 days)0.30.31.5-0.30.30.30.70.50.40.80.3-0.80.20.60.5-0.40.41.20.6
Intermittent access total infusions0.10.10.8-0.00.1-0.20.20.00.30.5-0.0-0.50.30.20.2-0.20.20.90.2
Intermittent access day 1 locomotion3.53.66.20.8-0.6-1.6-2.5-2.3-2.0-2.2-2.12.2-2.4-2.1-2.01.4-1.4-1.3-2.2
Intermittent access day 15 total locomotion2.12.25.32.2-2.3-1.0-1.2-1.2-1.3-1.0-1.71.0-1.3-1.3-1.51.8-1.8-1.2-1.2
Intermittent access total locomotion1.11.22.41.0-1.3-0.6-1.1-1.1-0.9-0.7-1.40.7-1.4-0.9-1.01.5-1.5-1.0-0.9
Intermittent access standard deviation0.50.61.6-0.30.30.21.10.80.81.30.3-1.30.60.90.8-0.30.30.50.9
Cocaine induced anxiety1.61.83.60.1-0.2-0.6-1.7-1.7-1.7-1.7-1.01.6-1.9-1.8-1.40.7-0.7-0.6-1.8
Post-drug Anxiety0.50.52.1-1.31.40.2-0.6-0.6-0.4-0.50.40.5-0.2-0.6-0.3-0.70.70.9-0.6
Baseline Anxiety1.92.03.7-1.11.11.01.61.61.91.61.3-1.61.81.71.5-0.80.80.61.7
Lifetime Intake0.30.31.6-0.00.3-0.40.40.20.50.60.1-0.60.50.40.2-0.60.61.30.3
Incentive Sensitization - Responses0.30.31.91.3-1.4-0.4-0.1-0.2-0.10.1-0.3-0.00.1-0.0-0.20.4-0.40.7-0.1
Incentive Sensitization - Breakpoint0.40.42.81.6-1.7-0.4-0.1-0.2-0.20.0-0.4-0.00.1-0.1-0.30.6-0.60.6-0.1
Progressive ratio test 1 active lever presses0.30.31.2-0.91.1-0.3-0.4-0.40.10.10.0-0.1-0.2-0.3-0.2-0.70.71.0-0.2
Progressive ratio test 1 breakpoint0.40.41.9-1.01.4-0.4-0.4-0.4-0.00.0-0.0-0.0-0.2-0.3-0.2-0.60.61.1-0.3
Progressive ratio test 1 inactive lever presses0.40.52.1-0.81.4-1.3-0.3-0.20.10.1-0.2-0.10.4-0.1-0.2-0.50.51.4-0.1
Progressive ratio test 2 active lever presses0.20.31.21.1-1.0-0.8-0.1-0.4-0.10.3-0.5-0.2-0.0-0.3-0.40.1-0.10.7-0.3
Progressive ratio test 2 breakpoint0.30.31.21.1-1.0-0.8-0.3-0.5-0.20.1-0.7-0.1-0.2-0.4-0.50.3-0.30.4-0.4
Progressive ratio test 2 inactive lever presses0.20.21.1-0.10.0-0.50.30.20.50.6-0.1-0.50.30.40.3-0.40.41.00.3
Total sessions with >9 infusions0.20.20.90.4-0.0-1.00.20.20.20.1-0.1-0.20.70.30.0-0.40.40.70.3
Short access day 1 total inactive lever presses1.41.68.5-2.32.9-1.30.30.20.20.60.2-0.60.50.40.4-1.21.22.20.3
Short access day 10 total inactive lever presses0.80.92.3-1.21.5-0.41.01.10.81.00.5-1.01.31.00.8-0.40.40.81.0
Short access day 1 total infusions1.21.24.7-1.21.7-0.90.60.50.80.60.6-0.60.90.50.6-1.71.72.20.5
Short access day 10 total infusions0.30.41.10.10.3-1.1-0.8-0.9-0.4-0.5-0.40.5-0.4-0.6-0.6-0.40.40.7-0.8
Short access total infusions0.20.21.3-0.10.4-0.8-0.0-0.30.20.2-0.1-0.20.0-0.0-0.1-0.80.81.1-0.1
Short access day 1 locomotion0.70.81.60.9-0.9-1.2-0.8-0.8-0.9-0.4-1.30.4-0.9-1.0-1.00.6-0.6-0.7-1.0
Short access day 10 total locomotion0.70.82.61.1-1.4-0.1-0.6-0.3-0.6-0.2-1.00.2-0.7-0.4-0.41.6-1.6-1.3-0.4
Short access total locomotion0.50.51.00.10.1-0.9-1.0-0.8-0.9-0.7-1.00.7-0.9-0.8-0.80.7-0.7-0.2-0.8
Compulsive drug intake0.20.20.3-0.10.5-0.3-0.5-0.3-0.4-0.5-0.20.5-0.5-0.6-0.50.1-0.10.4-0.6
One hour access (0.3 mA shock)0.20.20.80.9-0.6-0.60.2-0.1-0.20.4-0.3-0.40.5-0.1-0.40.5-0.50.9-0.1
One hour access (shock baseline)0.20.21.20.4-0.1-1.10.2-0.1-0.30.3-0.4-0.30.70.1-0.20.1-0.10.70.1
Number of responses in last shaping day0.30.41.80.40.5-1.3-0.3-0.2-0.0-0.30.10.30.7-0.2-0.4-0.90.90.9-0.2
Context. condit. distance diff. score0.20.20.6-0.50.4-0.4-0.4-0.4-0.4-0.4-0.60.4-0.8-0.4-0.40.4-0.4-0.4-0.4
Locomotion velocity, session 11.31.44.40.41.1-2.1-1.4-1.4-1.4-1.3-0.61.3-0.7-1.4-1.1-0.80.80.9-1.4
Locomotion distance, session 10.50.71.4-0.00.3-1.2-1.0-1.0-1.0-1.0-0.31.0-0.8-1.0-0.7-0.80.80.6-1.0
Locomotion velocity, session 21.21.42.3-1.41.01.30.91.01.01.01.5-1.01.11.01.2-1.51.51.31.0
Locomotion distance, session 20.71.03.6-1.11.3-0.10.40.40.50.41.0-0.40.60.50.7-1.91.91.70.5
Locomotion velocity, session 30.70.84.5-0.20.8-2.1-0.9-1.0-0.8-0.9-1.00.9-0.5-0.9-0.8-0.20.20.6-0.9
Locomotion distance, session 30.60.62.4-0.50.9-0.60.50.50.60.50.6-0.50.80.60.7-1.21.21.50.6
Stereotopy head waving bouts, day 30.10.10.30.20.50.0-0.3-0.3-0.3-0.30.40.30.0-0.3-0.2-0.50.50.6-0.3
Stereotopy head waving duration, day 30.10.10.3-0.10.40.50.10.10.00.10.5-0.10.30.00.2-0.30.30.30.0
Locomotion velocity, session 70.10.10.20.00.0-0.3-0.3-0.3-0.3-0.3-0.50.3-0.3-0.2-0.30.4-0.4-0.2-0.2
Locomotion distance, session 70.30.31.9-0.91.4-0.9-0.3-0.4-0.4-0.4-0.40.4-0.2-0.3-0.2-0.30.30.5-0.3
Stereotopy head waving bouts, day 72.93.35.7-1.52.01.51.61.61.51.62.3-1.62.01.51.9-2.42.42.11.5
Stereotopy head waving duration, day 71.51.93.6-0.71.11.41.21.31.21.31.9-1.31.61.21.4-1.71.71.41.2
Locomotion velocity, session 80.80.91.9-0.51.4-1.0-1.1-1.1-1.1-1.1-0.31.1-1.0-1.1-0.7-1.01.00.4-1.1
Locomotion distance, session 80.40.61.5-0.81.2-1.2-0.7-0.7-0.7-0.7-0.40.7-0.8-0.7-0.5-0.70.70.5-0.7
Degree of sensitization distance0.50.51.0-0.10.1-0.2-0.7-0.7-0.8-0.7-0.80.7-1.0-0.8-0.70.8-0.8-1.0-0.8
Degree of sensitization stereotypy1.61.73.2-1.11.41.01.11.11.11.11.7-1.11.41.11.4-1.81.81.41.1
Condit. Reinf. active minus inactive responses0.30.30.6-0.70.80.00.50.50.60.40.4-0.40.50.50.6-0.60.60.70.5
Condit. Reinf. active-inactive response ratio0.60.71.60.4-0.1-0.7-0.7-0.7-0.6-0.8-1.10.8-1.0-0.7-0.81.2-1.2-1.0-0.7
Condit. Reinf. active responses2.42.93.6-1.00.71.11.81.81.91.71.8-1.71.81.81.9-1.91.91.91.8
Condit. Reinf. inactive responses3.94.55.8-1.00.21.72.32.32.32.32.4-2.32.42.32.4-2.32.32.02.3
Incentive salience index mean2.42.85.7-1.31.30.81.51.51.61.51.9-1.51.71.61.7-2.22.22.41.6
Condit. Reinf. lever presses6.08.116.1-2.22.21.32.42.42.42.43.4-2.43.12.52.7-4.04.04.02.5
Time in familiar zone, hab. session 10.90.83.1-1.1-0.01.80.91.00.91.00.4-1.00.40.90.80.8-0.8-0.90.9
Time in novel zone, hab. session 13.93.86.82.6-2.0-2.2-2.2-2.2-2.1-2.2-1.72.2-1.6-2.1-2.10.7-0.7-0.8-2.1
Total zone transitions, hab. session 10.40.61.3-1.01.0-0.6-0.8-0.9-0.9-0.8-0.70.8-1.1-0.9-0.70.2-0.2-0.2-0.9
Total locomotion distance, hab. session 10.71.05.5-2.31.91.00.70.60.70.70.7-0.70.40.71.0-0.70.70.30.7
Locomotion velocity, hab. session 11.52.26.5-2.62.31.51.21.21.21.21.4-1.20.91.21.5-1.41.41.11.2
Time in familiar zone, hab. session 20.50.51.50.5-1.00.90.40.50.50.5-0.1-0.50.40.50.31.2-1.2-1.20.5
Time in novel zone, hab. session 22.72.84.31.1-0.7-1.8-2.0-2.0-2.0-2.1-1.52.1-2.0-2.1-1.90.5-0.5-0.4-2.1
Total zone transitions, hab. session 20.40.51.4-1.01.1-1.1-0.4-0.5-0.4-0.4-0.00.4-0.2-0.4-0.1-1.21.20.8-0.4
Total locomotion distance, hab. session 20.70.92.0-1.31.10.50.70.70.70.71.0-0.70.70.81.0-1.41.41.00.8
Locomotion velocity, hab. session 20.71.02.3-1.31.10.70.70.70.70.71.1-0.70.70.81.0-1.51.51.00.8
Novel to familiar place preference ratio5.65.98.61.9-1.0-2.2-2.7-2.7-2.8-2.8-2.62.8-2.9-2.8-2.81.8-1.8-1.6-2.8
Novelty place preference6.97.210.71.9-1.1-2.3-3.0-3.0-3.0-3.0-2.83.0-3.3-3.0-3.02.1-2.1-2.0-3.0
Time in novel zone, NPP test7.98.311.62.1-1.1-2.5-3.2-3.2-3.2-3.2-3.13.2-3.4-3.2-3.32.3-2.3-2.1-3.2
Total zone transitions, NPP test0.40.51.6-1.01.2-0.7-0.4-0.5-0.4-0.40.30.4-0.1-0.4-0.0-1.31.31.0-0.4
Total locomotion distance, NPP test0.91.23.8-1.41.6-0.10.60.60.60.61.1-0.61.00.60.9-1.91.91.60.6
Locomotion velocity, NPP test1.11.64.3-1.51.40.30.80.80.80.81.3-0.81.10.91.1-2.12.11.80.9
Pavlov. Cond. lever latency6.17.713.22.5-2.6-1.4-2.5-2.5-2.5-2.5-3.12.5-2.8-2.5-2.83.6-3.6-3.6-2.5
Pavlov. Cond. magazine entry latency0.20.20.80.4-0.60.90.20.30.30.20.8-0.20.30.30.3-0.50.50.50.3
Pavlov. Cond. change in total contacts1.81.93.6-1.11.4-0.11.31.21.41.31.1-1.31.31.31.3-1.81.81.91.3
Pavlov. Cond. index score2.22.94.7-1.21.01.41.51.61.61.52.2-1.51.71.61.7-2.12.12.11.6
Pavlov. Cond. latency score2.02.64.3-1.21.01.41.51.51.51.42.0-1.41.61.51.6-2.02.02.11.5
Pavlov. Cond. lever contacts4.14.88.1-1.92.01.32.02.02.02.02.5-2.02.22.02.2-2.82.82.92.0
Pavlov. Cond. magazine entry number0.30.41.00.1-0.0-0.8-0.5-0.5-0.5-0.4-1.00.4-0.6-0.5-0.50.9-0.9-0.8-0.5
Pavlov. Cond. intertrial magazine entries0.20.20.4-0.20.00.30.50.60.50.60.4-0.60.40.60.6-0.40.40.70.6
Pavlov. Cond. lever-magazine prob. diff.2.02.64.1-1.10.81.61.51.61.61.52.0-1.51.61.61.7-1.81.81.91.6
Pavlov. Cond. response bias1.82.24.1-1.00.91.11.31.31.41.31.9-1.31.51.41.5-2.02.02.01.4
Bone: apparent density1.01.72.9-1.71.31.01.31.31.31.21.4-1.11.21.31.4-1.21.21.31.3
Bone surface0.61.02.0-0.30.10.51.11.11.11.01.2-0.91.41.11.1-1.11.11.21.1
Bone volume0.40.71.4-0.70.30.80.80.80.70.71.2-0.70.90.80.9-1.11.11.10.8
Bone: connectivity density0.71.01.7-0.90.20.81.21.31.31.11.0-0.91.21.31.2-0.60.60.71.3
Bone: cortical apparent density0.10.21.8-0.40.01.40.20.20.20.20.2-0.2-0.40.20.30.3-0.3-0.50.2
Bone: cortical area3.45.27.4-1.00.82.72.52.62.42.42.7-2.52.62.52.5-1.91.91.82.5
Bone: cortical porosity0.70.81.8-0.40.3-0.1-1.1-1.1-1.1-1.1-0.61.1-1.3-1.2-0.80.2-0.2-0.6-1.2
Bone: cortical porosity0.30.30.8-0.80.90.1-0.6-0.6-0.6-0.60.00.6-0.7-0.7-0.3-0.40.40.1-0.7
Bone: cortical thickness1.62.75.0-1.30.82.21.71.81.81.61.9-1.71.71.81.9-1.31.30.91.8
Bone: cortical thickness0.10.20.4-0.70.40.30.40.40.40.40.2-0.50.40.50.4-0.10.1-0.40.5
Bone: cortical tissue density0.10.21.4-0.3-0.11.20.10.10.0-0.00.10.0-0.60.00.10.4-0.4-0.50.0
Bone: elastic displacement4.14.68.01.1-1.5-1.3-2.1-2.1-2.0-2.1-2.62.0-2.4-2.1-2.12.6-2.6-2.8-2.1
Bone: elastic work1.11.44.10.3-1.01.1-0.9-0.8-0.8-0.9-0.90.9-1.3-0.9-0.91.9-1.9-2.0-0.9
Bone: endosteal estimation0.61.22.60.30.20.51.21.21.01.21.3-1.31.61.11.0-1.11.11.61.1
Bone: endosteal perimeter0.71.53.10.70.00.91.21.21.01.21.6-1.31.51.11.0-1.31.31.81.1
Bone: final force1.01.73.7-0.81.21.81.11.21.11.01.9-1.01.31.11.2-1.41.41.61.1
Bone: final moment0.91.53.8-0.60.82.01.11.21.01.01.8-1.01.21.11.2-1.11.11.41.1
Bone: marrow area0.71.52.70.20.30.61.31.31.11.31.4-1.51.61.21.1-1.11.11.61.2
Bone: maximum diameter2.74.98.1-0.50.62.52.32.42.22.32.8-2.42.62.32.3-2.22.22.22.3
Bone: maximum force2.84.98.9-1.41.82.52.12.22.12.13.0-2.02.52.12.2-2.32.32.52.1
Bone: maximum moment2.44.27.5-1.11.32.62.02.12.02.02.7-1.92.32.02.1-1.91.92.22.0
Bone: minimum diameter0.10.20.60.7-0.60.80.20.20.10.20.2-0.30.40.20.00.6-0.6-0.30.2
Bone: periosteal estimation1.63.35.4-0.30.71.72.02.01.81.92.2-2.12.31.91.8-1.71.71.91.9
Bone: periosteal perimeter0.81.42.61.1-0.50.91.31.31.11.21.4-1.41.61.21.0-1.01.01.21.2
Bone: post-yield work1.62.13.80.3-0.11.31.51.61.51.61.9-1.51.91.51.4-1.31.31.71.5
Bone: stiffness4.16.59.8-1.92.12.42.62.62.52.53.1-2.42.82.52.6-2.62.62.82.5
Bone: tissue strength0.10.10.7-0.10.60.8-0.00.00.0-0.00.60.10.0-0.00.1-0.30.30.3-0.0
Bone: trabecular number1.01.52.5-1.61.01.31.31.31.31.21.4-1.01.11.31.4-1.01.01.21.3
Bone: trabecular spacing0.20.20.9-0.2-0.11.00.50.50.40.50.5-0.60.20.50.5-0.20.2-0.00.5
Bone: trabecular thickness0.40.40.8-0.3-0.1-0.4-0.8-0.8-0.9-0.8-0.50.8-0.8-0.9-0.70.3-0.3-0.4-0.9
Bone: trabecular tissue density3.44.87.9-2.82.81.21.91.91.92.12.1-2.11.82.02.3-2.62.62.22.0
Breakpoint value in progressive ratio session0.50.61.31.1-0.3-1.1-0.9-0.7-0.9-1.0-0.61.00.0-0.6-1.00.6-0.6-0.4-0.6
Distance traveled before self-admin3.84.015.0-3.23.9-0.21.01.00.51.01.7-1.11.20.81.3-3.13.12.90.7
Distance traveled after self-admin3.33.75.4-1.91.51.32.32.22.02.11.9-1.71.42.12.3-2.12.11.52.0
Delta time in closed arm before/after self-admin1.31.22.0-0.1-0.61.41.31.21.21.41.1-1.40.61.31.4-0.90.91.01.2
Delta time in open arm before/after self-admin0.20.21.11.1-0.50.0-0.2-0.2-0.2-0.1-0.20.1-0.0-0.3-0.50.7-0.7-0.2-0.2
Diff in mean of infusions in LGA sessions0.20.20.80.8-0.9-0.10.10.00.0-0.0-0.50.2-0.00.50.00.9-0.9-0.40.4
Extinction: sum of active levers before priming0.90.92.40.7-0.5-0.9-0.7-0.7-0.5-0.7-1.30.8-1.0-0.6-0.91.6-1.6-1.2-0.6
Active lever presses in extinction session 60.80.82.81.4-1.70.1-0.6-0.7-1.1-0.8-0.30.6-0.2-0.7-0.70.4-0.4-1.5-0.8
Delta distance traveled before/after self-admin0.50.53.01.1-1.70.50.70.70.80.50.1-0.10.10.70.50.2-0.2-0.50.7
Delta ambulatory time before/after self-admin0.50.54.11.1-2.00.20.60.50.80.4-0.20.1-0.10.50.50.1-0.1-0.90.6
Time in closed arm before self-admin2.42.75.61.5-1.2-0.7-1.4-1.4-1.6-1.6-1.71.5-1.3-1.6-1.82.2-2.2-2.4-1.5
Time in closed arm after self-admin0.20.20.80.4-0.7-0.2-0.3-0.2-0.3-0.4-0.60.3-0.6-0.2-0.20.6-0.6-0.9-0.2
Time in open arm before self-admin1.41.54.8-2.12.2-0.8-0.1-0.20.10.00.70.10.0-0.10.4-2.22.22.1-0.2
Time in open arm after self-admin0.80.92.8-0.71.00.10.60.50.60.81.1-0.70.80.60.7-1.51.51.70.6
Sum of active levers in priming session hrs 5-62.72.77.22.7-2.1-1.6-1.0-1.3-1.3-0.9-1.91.1-1.0-1.1-1.72.1-2.1-1.9-1.1
Time to tail flick, vehicle, before self-admin1.61.63.11.6-1.6-0.7-1.1-1.0-1.3-1.2-1.31.1-0.3-1.2-1.21.8-1.8-1.5-1.0
Time to tail flick, vehicle, after self-admin0.70.81.70.5-0.30.51.21.30.91.10.7-0.81.31.20.9-0.10.1-0.01.3
Time to tail flick, test, before self-admin0.60.61.2-0.70.90.51.10.90.80.90.5-0.90.50.70.8-0.30.30.60.9
Time to tail flick, test, after self-admin0.30.31.50.6-1.01.2-0.00.00.00.00.20.3-0.8-0.0-0.10.9-0.9-0.2-0.1
Delta time to tail flick, vehicle, before/after SA1.21.22.0-0.20.10.91.41.31.21.31.1-1.10.81.41.2-1.01.00.71.4
Delta time to tail flick, test, before/after SA1.21.12.31.3-1.50.0-1.0-1.0-0.9-0.8-0.71.0-1.2-0.8-1.11.3-1.3-0.8-1.0
Ambulatory time before self-admin2.82.913.1-2.93.6-0.70.80.60.30.71.1-0.90.90.51.0-2.62.62.40.5
Ambulatory time after self-admin2.02.23.8-1.31.00.21.91.61.71.61.2-1.21.21.51.7-1.91.91.01.5
Total heroin consumption0.40.40.90.50.1-0.9-0.6-0.5-0.7-0.7-0.70.7-0.0-0.6-0.91.0-1.0-0.2-0.6
Area under the delay curve0.30.41.21.1-1.0-0.5-0.3-0.3-0.5-0.3-0.70.2-0.5-0.5-0.60.5-0.5-0.9-0.5
Delay disc. indifference point, 0s delay0.80.81.30.10.7-0.9-0.9-0.9-1.1-0.9-0.90.9-0.9-1.0-1.11.0-1.0-0.9-0.9
Delay disc. indifference point, 16s delay1.01.04.62.1-1.9-1.1-0.4-0.5-0.5-0.3-1.10.2-0.1-0.8-1.00.9-0.9-0.7-0.7
Delay disc. indifference point, 2s delay0.10.21.6-0.20.11.20.30.10.00.30.6-0.3-0.2-0.10.2-0.10.10.20.1
Delay disc. indifference point, 24s delay0.20.21.40.9-1.20.2-0.1-0.1-0.1-0.1-0.40.0-0.4-0.2-0.30.2-0.2-0.7-0.3
Delay disc. indifference point, 4s delay0.10.10.40.3-0.3-0.10.20.2-0.10.2-0.4-0.2-0.50.1-0.00.6-0.6-0.60.1
Delay disc. indifference point, 8s delay0.10.10.50.4-0.70.40.40.40.20.30.1-0.40.00.30.2-0.20.2-0.40.2
Delay discount exponential model param0.30.31.1-1.11.10.50.20.30.50.20.7-0.20.50.40.5-0.40.40.90.4
Delay discount hyperbolic model param0.30.31.0-1.00.90.50.20.40.50.30.7-0.20.60.50.6-0.40.40.80.5
Fecal boli incidents, locomotor time 11.92.14.92.2-2.1-0.6-0.6-0.8-1.3-0.3-1.60.3-1.3-1.2-1.52.2-2.2-1.3-1.2
Change in fecal boli incidents, locomotor task1.51.45.3-1.92.1-0.6-0.4-0.30.7-0.40.70.40.20.30.6-2.32.31.00.1
Time >=10cm from walls, locomotor time 10.60.61.40.10.2-0.6-1.0-1.0-0.9-1.1-0.41.2-0.7-1.0-0.9-0.10.10.0-1.1
Bouts of movement, locomotor time 10.50.61.70.3-0.4-1.3-0.4-0.5-0.4-0.7-1.30.5-0.3-0.5-0.61.3-1.3-0.8-0.5
Total resting periods, locomotor time 11.01.13.40.9-1.2-0.9-0.5-0.7-0.6-0.7-1.40.6-0.6-0.7-0.81.8-1.8-1.1-0.7
Rest time, locomotor task time 10.70.82.60.7-1.41.6-0.3-0.4-0.3-0.3-0.30.2-0.9-0.4-0.41.4-1.4-1.1-0.5
Distance moved, locomotor task time 10.80.95.1-1.32.3-1.4-0.10.20.1-0.00.30.20.80.40.2-1.11.11.50.4
Vertical activity count, locomotor time 10.70.83.5-1.01.9-1.3-0.4-0.1-0.3-0.40.30.60.2-0.10.1-1.31.31.40.1
Time >=10cm from walls, locomotor time 20.60.71.5-0.50.9-0.9-0.8-0.8-1.2-0.8-0.60.9-1.0-1.0-1.00.1-0.10.2-1.1
Bouts of movement, locomotor time 23.03.26.60.7-1.21.32.42.22.02.41.5-2.62.11.91.8-1.11.10.91.9
Total resting periods, locomotor time 22.22.45.10.9-1.31.12.21.91.72.11.2-2.31.81.61.5-0.70.70.51.6
Rest time, locomotor task time 20.50.51.20.5-0.90.1-0.5-0.8-0.6-0.6-0.70.4-0.7-0.8-0.71.1-1.1-0.7-0.8
Distance moved, locomotor task time 20.20.21.5-0.81.20.0-0.10.4-0.0-0.10.10.30.10.30.10.3-0.30.40.2
Vertical activity count, locomotor time 20.20.21.3-0.51.2-0.1-0.40.0-0.4-0.20.30.4-0.1-0.2-0.2-0.30.30.7-0.2
Weight adjusted by age0.40.41.9-0.40.9-1.4-0.7-0.5-0.2-0.7-0.00.60.6-0.4-0.2-0.60.60.6-0.3
Seeking ratio, delayed vs. immediate footshock1.61.96.8-2.12.60.21.31.01.31.31.0-1.21.21.11.1-0.90.91.91.1
Locomotion in novel chamber0.30.41.9-1.41.30.7-0.10.20.2-0.10.50.1-0.5-0.00.3-1.01.0-0.2-0.0
Locomotion in novel chamber post-restriction3.94.77.9-0.6-0.42.82.32.62.32.32.4-2.41.82.42.6-2.12.11.12.4
Progressive ratio0.30.41.11.0-1.0-0.40.50.70.80.3-0.3-0.40.60.90.30.4-0.4-0.60.8
Food seeking constrained by brief footshock6.57.913.1-2.02.81.12.62.72.82.63.2-2.53.12.72.7-3.43.43.62.7
Seeking ratio, punishment vs. effort1.92.35.9-1.82.21.01.00.90.91.21.9-1.01.20.71.2-2.12.12.40.8
Run reversals in cocaine runway, females0.30.21.3-1.11.10.00.30.40.40.1-0.2-0.20.10.40.40.0-0.0-0.70.4
Run reversals in cocaine runway, males0.20.20.5-0.40.3-0.6-0.7-0.40.2-0.7-0.40.7-0.1-0.3-0.30.7-0.7-0.1-0.4
Latency to leave start box in cocaine runway0.91.03.0-1.71.70.90.50.50.60.41.3-0.20.70.60.9-1.41.41.00.4
Latency to leave start box in cocaine runway, F0.40.41.5-0.10.3-0.2-1.0-0.9-0.6-1.0-0.11.2-0.3-0.7-0.60.1-0.1-0.1-0.8
Latency to leave start box in cocaine runway, M2.42.36.3-2.52.40.40.80.90.80.81.5-0.80.70.71.3-2.52.51.80.7
Cd content in liver1.92.15.0-0.5-0.22.21.71.71.71.71.6-1.71.31.71.6-0.80.80.71.7
Co content in liver0.70.82.81.6-1.7-0.9-0.5-0.5-0.6-0.5-1.00.5-0.2-0.5-0.81.0-1.0-0.8-0.5
Cu content in liver0.20.31.20.3-1.10.5-0.4-0.4-0.3-0.4-0.20.4-0.3-0.4-0.30.6-0.6-1.1-0.4
Fe content in liver0.30.42.21.5-0.9-0.2-0.2-0.1-0.1-0.20.50.20.5-0.1-0.2-0.90.90.8-0.2
K content in liver0.60.61.60.3-0.5-1.3-0.9-0.9-0.8-0.9-0.90.9-0.6-0.8-0.80.2-0.2-0.5-0.9
Mg content in liver1.11.21.40.7-1.2-0.9-1.2-1.2-1.1-1.2-1.11.2-1.0-1.2-1.20.9-0.9-1.2-1.2
Mn content in liver1.11.21.8-1.10.51.01.31.31.31.31.0-1.30.91.31.3-0.80.80.61.3
Na content in liver0.60.61.40.8-1.2-0.2-0.6-0.6-0.6-0.6-0.80.6-0.9-0.6-0.70.9-0.9-1.1-0.6
Rb content in liver3.84.76.82.3-1.9-2.0-2.0-2.0-2.1-2.0-2.62.0-1.9-2.1-2.32.6-2.6-2.2-2.0
Se content in liver4.25.17.4-2.21.91.72.52.52.72.52.1-2.52.52.62.5-1.71.71.52.5
Sr content in liver0.60.61.3-1.11.10.80.60.60.60.60.8-0.60.50.60.7-0.80.80.80.6
Zn content in liver0.10.10.5-0.7-0.10.60.30.30.40.30.3-0.30.50.30.40.1-0.1-0.20.3