Hub : Genes

Pclo

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000005726 0.17 0.09 0.0e+00 0.16 0.15 0.15 0.12 8.1e-17 8.7e-17 2.9e-16 4.9e-13
2 BLA gene expression ENSRNOG00000005726 0.08 0.05 5.7e-05 0.07 0.08 0.07 0.07 1.1e-04 4.5e-05 1.0e-04 8.5e-05
3 BLA mRNA stability ENSRNOG00000005726 0.11 0.08 9.1e-04 0.03 0.03 0.03 0.02 6.5e-03 7.8e-03 1.4e-02 2.1e-02
4 Brain alternative polyA ENSRNOT00000007608 0.08 0.06 2.3e-03 0.03 0.01 0.03 0.04 1.5e-03 2.0e-02 7.0e-04 2.3e-04
5 Brain alternative polyA ENSRNOT00000008637 0.08 0.06 2.0e-03 0.03 0.01 0.03 0.04 1.6e-03 1.8e-02 7.1e-04 1.9e-04
6 Brain gene expression ENSRNOG00000005726 0.04 0.03 1.8e-04 0.04 0.02 0.03 0.03 1.3e-04 4.3e-03 6.6e-04 1.1e-03
7 Brain isoform ratio ENSRNOT00000007608 0.05 0.04 6.9e-03 0.01 0.01 0.03 0.01 5.4e-02 6.2e-02 1.0e-03 3.2e-02
8 Brain isoform ratio ENSRNOT00000008637 0.05 0.05 5.2e-03 0.01 0.01 0.03 0.01 4.4e-02 4.0e-02 5.5e-04 2.1e-02
9 Brain mRNA stability ENSRNOG00000005726 0.28 0.11 0.0e+00 0.19 0.2 0.24 0.22 3.0e-17 9.3e-19 4.1e-22 1.2e-20
10 IL gene expression ENSRNOG00000005726 0.39 0.19 2.9e-03 0.05 0.1 0.1 0.06 2.4e-02 2.4e-03 2.4e-03 1.5e-02
11 LHb intron excision ratio chr4:19838555:19842972 0.18 0.11 9.5e-03 0.05 0.04 0.05 0.04 3.0e-02 3.6e-02 2.9e-02 5.3e-02
12 Liver gene expression ENSRNOG00000005726 0.02 0.02 4.1e-03 0 0.01 0 0 3.2e-01 1.5e-02 8.1e-02 1.3e-01
13 NAcc gene expression ENSRNOG00000005726 0.07 0.05 2.0e-03 0.03 0.03 0.03 0.03 2.5e-03 4.3e-03 4.6e-03 4.4e-03
14 PL alternative polyA ENSRNOT00000008637 0.19 0.11 8.1e-03 0.04 0.02 0.04 0.03 4.8e-04 6.6e-03 1.1e-03 1.2e-03
15 PL gene expression ENSRNOG00000005726 0.43 0.18 1.1e-03 0 0.01 0 0 1.4e-01 6.7e-02 2.6e-01 2.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.20.72.1-0.50.6-0.61.1-1.10.61.4-1.4-0.80.90.40.20.5-0.21.0
BMI without tail1.73.69.2-1.60.9-1.82.7-2.70.93.0-3.0-2.30.31.7-0.22.10.11.2
Body weight0.10.51.40.51.10.30.3-0.21.10.3-0.30.11.2-0.41.00.30.61.1
Epididymis fat weight0.61.45.60.22.00.60.0-0.02.0-0.40.40.60.6-0.81.71.32.40.9
Glucose0.30.52.10.4-1.10.3-0.50.5-1.1-0.10.10.30.4-0.2-0.5-1.5-1.3-0.2
Heart weight2.63.85.62.41.92.2-2.02.01.8-2.01.92.01.6-2.22.3-0.72.01.4
Left kidney weight0.10.42.90.70.60.20.3-0.30.50.4-0.50.11.7-0.40.7-0.4-0.40.7
Right kidney weight0.31.02.10.01.1-0.71.4-1.41.01.2-1.2-0.91.40.20.70.80.21.0
Tail length0.31.02.1-0.90.2-1.01.4-1.40.21.3-1.3-1.3-0.41.1-0.41.30.30.0
Length with tail0.00.10.20.10.1-0.20.3-0.20.2-0.30.4-0.3-0.10.20.00.40.4-0.2
Length without tail0.61.33.71.40.11.2-1.41.40.1-1.91.91.40.5-1.20.7-1.20.4-0.4
Liver weight, left0.30.51.61.20.10.6-0.60.60.3-0.70.60.61.3-0.70.5-0.9-0.30.4
Liver weight, right0.61.03.80.3-0.3-1.60.8-0.9-0.40.1-0.1-1.31.70.4-0.4-0.3-1.91.3
Parametrial fat weight0.10.30.6-0.7-0.7-0.40.2-0.2-0.50.3-0.3-0.4-0.80.5-0.7-0.1-0.5-0.8
Retroperitoneal fat weight0.30.92.5-1.10.6-0.71.2-1.20.51.3-1.3-0.9-0.70.7-0.01.60.70.3
Intraocular pressure0.81.12.50.1-1.00.6-1.31.4-0.9-1.51.61.1-1.5-0.5-0.5-1.0-0.2-0.6
Extensor digitorum longus weight0.31.33.0-1.2-1.7-1.10.5-0.4-1.7-0.20.3-1.1-1.41.2-1.7-0.3-1.5-0.8
Soleus weight6.819.834.94.92.05.0-5.95.92.1-5.95.85.62.2-5.53.8-3.22.62.3
Tibialis anterior weight0.82.64.41.91.01.9-1.91.91.1-1.51.42.01.3-2.11.6-1.00.71.9
Tibia length0.20.61.40.70.90.8-0.50.60.9-1.21.10.70.6-0.60.90.41.00.1
Number of licking bursts0.60.72.00.80.81.1-0.80.80.8-1.01.01.00.0-0.90.9-0.01.40.1
Food consumed during 24 hour testing period0.60.71.90.6-0.01.1-1.41.40.2-0.90.91.4-0.1-1.10.5-0.90.4-0.1
Times rat made contact with spout0.50.62.0-1.40.1-0.80.7-0.70.00.5-0.4-0.5-1.40.7-0.41.30.7-0.2
Mean time between licks in bursts1.01.42.7-1.4-0.5-1.61.6-1.6-0.51.2-1.1-1.5-1.01.2-1.11.1-0.60.3
Mean num. licks in bursts0.80.91.8-1.3-0.7-1.41.0-1.0-0.81.0-1.0-1.0-0.81.1-1.10.5-1.0-0.2
Std. dev. time between licks in bursts1.51.83.5-1.6-1.1-1.91.5-1.5-1.11.1-1.1-1.8-1.11.6-1.60.6-1.3-0.3
Water consumed over 24 hours0.20.21.2-0.8-0.6-0.20.0-0.0-0.50.3-0.3-0.0-1.10.2-0.50.1-0.0-0.5
Indifference point 0 sec0.10.20.6-0.30.70.6-0.00.00.60.3-0.30.2-0.2-0.10.40.80.80.5
Indifference point AUC0.50.52.21.10.10.2-0.40.40.3-0.20.10.31.5-0.90.5-0.9-0.51.4
Indifference point function ln k0.40.63.0-0.6-0.60.5-0.50.5-0.7-0.50.60.4-1.40.2-0.5-0.10.4-1.7
Indifference point function log k0.40.63.0-0.6-0.60.5-0.50.5-0.7-0.50.60.4-1.40.2-0.5-0.10.4-1.7
Delay discounting total patch changes 0 sec0.20.30.8-0.10.90.70.0-0.00.80.4-0.50.20.1-0.20.70.80.90.8
Delay discounting total patch changes 12 sec0.50.72.61.00.90.6-0.50.51.0-0.30.20.41.5-0.81.0-0.10.11.6
Delay discounting total patch changes 18 sec0.81.13.21.21.11.2-0.70.81.2-0.20.20.91.2-1.31.3-0.30.91.8
Delay discounting total patch changes 24 sec1.72.13.71.90.71.4-1.61.60.8-1.41.41.31.9-1.81.4-1.40.01.9
Delay discounting total patch changes 6 sec1.52.36.5-0.52.20.20.8-0.92.21.6-1.7-0.0-0.0-0.31.42.62.12.2
Delay discounting time to switch 0 sec0.40.62.40.11.40.00.4-0.41.40.1-0.10.10.0-0.00.91.41.60.2
Delay discounting water rate 0 sec0.61.03.01.0-0.81.0-1.31.4-0.8-1.21.20.90.5-0.9-0.0-1.7-0.8-0.2
Delay discounting water rate 12 sec2.23.37.31.80.32.7-2.62.60.2-2.02.02.70.1-2.11.2-1.51.4-0.4
Delay discounting water rate 18 sec2.43.26.91.5-0.02.4-2.62.6-0.2-2.62.62.4-0.0-1.90.8-1.70.8-0.5
Delay discounting water rate 24 sec1.52.15.51.4-1.01.8-1.91.9-1.0-1.61.61.80.1-1.30.0-2.3-0.4-1.1
Delay discounting water rate 6 sec1.72.55.61.6-0.41.5-2.32.3-0.2-2.42.41.90.3-1.70.6-1.90.0-0.3
Locomotor activity0.30.52.10.60.90.20.4-0.41.00.6-0.6-0.31.5-0.30.90.10.31.1
Locomotor testing distance0.71.13.51.60.31.3-0.90.90.6-0.60.60.71.9-1.20.9-1.5-0.30.9
Locomotor testing rearing0.30.41.90.40.0-0.70.4-0.40.20.0-0.1-0.71.3-0.10.1-0.4-0.91.4
Light reinforcement 10.40.82.50.01.50.20.2-0.21.40.2-0.30.20.6-0.51.11.11.21.6
Light reinforcement 20.20.31.2-0.9-0.6-0.30.1-0.1-0.80.1-0.1-0.1-1.10.4-0.70.1-0.1-0.9
Reaction time number correct0.81.22.51.11.61.3-0.40.41.5-0.50.50.91.3-1.11.60.21.50.3
Reaction time mean minus median1.51.94.1-1.3-1.1-1.81.7-1.7-1.21.4-1.4-2.00.01.6-1.40.2-1.7-0.6
Reaction time mean minus median AUC2.02.55.0-1.7-1.4-2.01.8-1.8-1.51.4-1.4-2.2-0.21.9-1.80.1-2.0-0.8
Reaction time num false alarms0.30.41.50.2-1.10.3-0.20.3-1.00.1-0.1-0.10.00.1-0.7-1.2-1.2-0.5
Reaction time num false alarms AUC0.60.83.30.5-1.30.8-0.80.9-1.2-0.40.40.40.2-0.3-0.6-1.8-1.4-0.5
Reaction time trials correct on left0.81.22.51.11.61.3-0.40.41.5-0.50.50.91.3-1.11.60.21.50.3
Reaction time trials on left0.71.02.51.01.61.1-0.30.31.5-0.40.30.71.4-1.01.50.31.40.4
Reaction time mean2.12.95.4-1.6-1.3-2.02.1-2.1-1.42.0-1.9-2.3-0.52.1-1.80.4-1.9-0.5
Reaction time mean AUC2.53.46.1-1.7-1.6-2.22.2-2.1-1.62.0-2.0-2.5-0.52.2-2.00.3-2.3-0.6
Median of all reaction times1.62.23.8-1.3-1.1-1.61.9-1.8-1.11.9-1.8-2.0-0.41.8-1.50.3-1.6-0.4
Reaction time omissions3.54.710.7-2.1-0.4-3.13.0-3.0-0.52.6-2.5-3.30.42.4-1.31.4-1.91.0
Reaction time false alarm rate0.71.03.4-0.2-1.9-0.0-0.50.5-1.8-0.10.1-0.2-0.80.4-1.3-1.5-1.8-0.7
Reaction time premature initiation rate0.40.51.4-0.80.5-0.20.7-0.70.30.9-0.9-0.2-0.70.50.11.11.2-0.6
Reaction time premature initiations0.30.52.9-0.21.10.50.3-0.30.90.4-0.40.3-0.0-0.10.70.91.7-0.6
Std. dev. reaction times2.93.97.4-2.1-1.6-2.42.4-2.3-1.72.1-2.0-2.7-0.52.4-2.10.4-2.3-0.7
Reaction time trials completed0.71.02.51.01.61.1-0.30.31.5-0.40.30.71.4-1.01.50.31.40.4
Reaction time trials AUC0.91.22.71.11.71.3-0.50.41.5-0.50.50.91.4-1.11.60.21.60.4
Social response proportion0.10.10.4-0.3-0.1-0.60.5-0.50.00.1-0.1-0.60.10.3-0.20.2-0.0-0.2
Social responses0.50.71.6-0.80.3-1.21.1-1.10.40.9-0.9-1.30.70.7-0.20.8-0.50.8
Social time0.40.51.40.71.10.70.4-0.40.90.5-0.50.21.0-0.31.00.21.20.1
Conditioned locomotion0.40.51.0-0.6-0.8-0.90.4-0.4-1.0-0.30.4-0.8-0.80.7-0.90.1-0.8-0.4
Cocaine response after cond. corrected0.60.62.60.01.30.4-0.0-0.01.10.5-0.60.4-0.1-0.31.01.11.60.8
Cocaine response after cond. not corrected0.10.10.20.20.40.1-0.10.10.30.2-0.30.2-0.0-0.20.30.20.50.3
Cocaine response before conditioning0.70.83.80.5-1.4-0.5-0.20.3-1.2-0.70.7-0.30.60.0-0.8-1.5-1.9-0.4
Saline control response0.10.10.40.6-0.30.2-0.10.1-0.3-0.10.1-0.10.6-0.1-0.1-0.7-0.5-0.4
Condit. Reinf. active minus inactive responses0.60.82.30.60.50.7-1.11.00.6-1.51.51.00.5-1.00.7-0.40.50.4
Condit. Reinf. active-inactive response ratio0.30.41.30.4-0.10.4-0.80.8-0.0-1.11.10.60.2-0.60.2-0.7-0.0-0.0
Condit. Reinf. active responses0.30.41.70.10.50.1-0.60.60.5-1.31.30.30.2-0.50.50.20.30.8
Condit. Reinf. inactive responses0.30.42.0-0.50.6-0.80.6-0.50.60.0-0.0-0.70.20.30.21.0-0.01.4
Condit. Reinf. lever presses3.04.211.81.13.40.9-0.50.53.3-0.80.71.01.7-1.62.91.92.93.0
Condit. Reinf. lever reinforcers received0.40.61.80.30.90.2-0.70.60.9-1.31.30.40.4-0.70.80.40.71.1
Pavlov. Cond. lever latency2.22.98.6-1.1-2.9-0.40.1-0.0-2.90.3-0.2-0.4-2.11.1-2.4-1.5-2.0-2.8
Pavlov. Cond. magazine entry latency0.60.62.00.31.4-0.1-0.0-0.01.4-0.50.40.10.9-0.41.10.91.01.2
Pavlov. Cond. change in total contacts1.41.96.90.82.2-0.2-0.20.22.2-0.70.60.21.5-0.81.81.31.32.6
Pavlov. Cond. index score1.92.57.11.02.70.2-0.20.22.6-0.80.70.51.9-1.12.21.41.82.5
Pavlov. Cond. latency score1.92.36.21.22.50.4-0.40.42.5-0.90.80.71.9-1.22.21.11.72.3
Pavlov. Cond. lever contacts2.83.911.51.23.40.5-0.10.13.3-0.70.50.52.3-1.32.81.82.43.0
Pavlov. Cond. magazine entry number0.60.72.2-0.2-1.50.3-0.20.2-1.40.5-0.40.0-0.80.3-1.1-1.1-1.0-1.2
Pavlov. Cond. intertrial magazine entries0.50.72.0-0.0-1.40.5-0.10.1-1.30.4-0.30.2-0.00.1-0.9-1.4-1.4-1.1
Pavlov. Cond. lever-magazine prob. diff.2.02.67.21.12.70.2-0.30.22.6-0.80.70.51.9-1.12.31.41.82.6
Pavlov. Cond. response bias2.23.09.00.93.00.3-0.0-0.02.9-0.60.50.31.8-1.02.41.82.22.8
Conditioned reinforcement - actives1.81.83.71.91.11.9-1.21.21.0-0.70.61.71.4-1.81.6-1.21.30.5
Conditioned reinforcement - inactives0.40.51.20.60.51.1-0.80.80.6-0.10.10.90.0-0.90.7-0.41.0-0.2
Conditioned locomotion1.31.53.61.90.71.3-1.21.21.0-1.31.21.11.7-1.51.3-1.30.40.8
Intermittent access intake day 1-15 change3.23.27.02.41.31.8-1.91.91.4-1.21.11.82.6-2.32.0-1.30.51.9
Intermittent access intake escalation2.72.77.62.20.91.5-1.71.81.0-1.11.11.52.8-2.11.6-1.7-0.31.8
Intermittent access intake escalation 21.01.02.91.2-0.41.0-1.11.1-0.1-0.80.80.91.4-1.20.4-1.7-0.80.0
Intermitt. access day 1 inactive lever presses3.63.99.0-1.7-3.0-1.90.5-0.4-2.8-0.20.3-1.8-2.42.0-2.9-0.5-2.6-2.4
Intermitt. access day 15 inactive lever presses0.50.51.0-0.6-0.9-0.70.7-0.6-1.00.6-0.6-1.0-0.40.7-0.9-0.2-0.8-0.7
Intermitt. access escalation Index3.43.05.2-2.3-0.8-1.81.9-1.9-1.02.2-2.1-1.9-2.22.1-1.61.7-0.3-0.8
Intermittent access day 1 total infusions0.20.21.20.10.20.4-0.50.40.2-0.20.20.4-1.1-0.30.10.31.1-0.5
Intermittent access day 15 total infusions0.91.12.31.30.91.3-1.21.20.9-0.40.31.20.7-1.51.2-0.41.00.8
Intermittent access terminal intake (last 3 days)0.70.71.60.70.21.2-1.31.30.2-0.60.61.2-0.4-1.20.6-0.51.1-0.2
Intermittent access total infusions0.70.81.90.70.21.2-1.41.40.2-0.80.81.2-0.6-1.10.6-0.51.2-0.4
Intermittent access day 1 locomotion0.30.31.00.3-0.20.3-1.01.0-0.0-1.01.00.4-0.6-0.4-0.0-0.30.2-0.2
Intermittent access day 15 total locomotion2.22.35.92.11.31.0-1.51.51.6-1.21.11.22.4-1.81.7-0.90.21.9
Intermittent access total locomotion1.61.83.81.50.41.4-2.01.90.7-1.61.61.70.8-1.71.1-1.20.50.7
Intermittent access standard deviation0.10.10.90.40.1-0.20.0-0.10.10.1-0.2-0.30.9-0.10.1-0.1-0.60.5
Cocaine induced anxiety0.50.62.3-0.4-0.9-0.50.7-0.7-1.00.3-0.3-0.6-0.40.9-0.9-0.6-0.6-1.5
Post-drug Anxiety0.70.82.6-0.8-1.2-0.60.3-0.3-1.3-0.50.5-0.5-1.21.0-1.2-0.4-0.6-1.6
Baseline Anxiety0.30.30.9-1.0-0.3-0.80.3-0.3-0.5-0.10.1-0.5-0.80.6-0.60.7-0.3-0.0
Lifetime Intake0.70.82.20.90.91.2-1.11.00.7-0.50.41.2-0.0-1.21.0-0.11.50.1
Incentive Sensitization - Responses0.20.20.60.50.20.6-0.70.60.1-0.10.10.60.2-0.80.4-0.50.40.4
Incentive Sensitization - Breakpoint0.30.30.80.60.20.8-0.80.70.1-0.20.20.70.2-0.90.5-0.60.40.4
Progressive ratio test 1 active lever presses0.50.51.80.51.00.6-0.50.50.90.0-0.00.6-0.1-0.60.90.61.40.7
Progressive ratio test 1 breakpoint0.40.52.30.21.00.5-0.30.30.80.2-0.20.4-0.5-0.30.70.91.50.6
Progressive ratio test 1 inactive lever presses0.40.40.8-0.6-0.7-0.90.3-0.3-0.7-0.00.0-0.8-0.90.8-0.80.3-0.7-0.2
Progressive ratio test 2 active lever presses0.40.51.00.70.70.8-0.80.80.5-0.30.20.80.1-1.00.8-0.11.00.7
Progressive ratio test 2 breakpoint0.40.51.20.70.60.9-0.90.80.4-0.30.30.9-0.1-1.00.8-0.11.10.4
Progressive ratio test 2 inactive lever presses0.20.30.9-0.1-0.70.0-0.50.5-0.8-0.40.4-0.1-1.0-0.0-0.6-0.5-0.2-0.5
Total sessions with >9 infusions0.20.20.8-0.10.9-0.0-0.20.10.6-0.10.10.3-0.1-0.20.60.70.90.6
Short access day 1 total inactive lever presses0.60.71.51.1-0.20.9-1.21.20.0-0.90.90.70.5-1.00.3-1.0-0.00.1
Short access day 10 total inactive lever presses1.21.42.7-1.2-1.3-1.51.0-0.9-1.10.7-0.6-1.6-1.11.2-1.60.4-1.4-0.8
Short access day 1 total infusions0.30.31.1-0.20.5-0.00.4-0.40.40.7-0.8-0.1-0.5-0.00.30.91.00.0
Short access day 10 total infusions1.51.64.51.21.81.4-0.90.81.6-0.30.21.30.7-1.51.80.42.11.1
Short access total infusions0.30.31.70.41.00.4-0.10.00.80.3-0.30.30.1-0.40.80.61.30.1
Short access day 1 locomotion1.01.12.5-1.4-0.5-0.91.2-1.2-0.51.0-1.0-0.8-1.61.0-0.91.10.2-1.2
Short access day 10 total locomotion2.02.23.92.00.81.4-1.91.91.2-1.91.81.51.2-1.71.4-0.90.71.0
Short access total locomotion0.50.50.90.60.70.5-0.90.90.8-1.00.90.70.2-0.80.80.20.90.6
Compulsive drug intake0.40.41.30.6-0.4-0.4-0.20.3-0.3-0.50.5-0.41.1-0.2-0.1-1.1-1.10.8
One hour access (0.3 mA shock)0.60.71.31.10.81.0-1.01.00.8-0.50.50.90.7-1.11.0-0.51.00.5
One hour access (shock baseline)0.50.62.10.30.61.0-0.80.80.4-0.40.41.1-0.6-0.80.60.11.5-0.6
Number of responses in last shaping day1.11.13.20.60.40.9-1.41.40.3-1.81.81.3-0.2-1.10.6-0.40.90.0
Context. condit. distance diff. score1.21.44.5-0.71.4-1.01.4-1.41.31.5-1.6-0.90.20.60.52.10.91.0
Locomotion velocity, session 10.91.03.20.30.11.1-1.11.10.2-1.81.81.0-1.1-0.80.3-0.11.1-0.3
Locomotion distance, session 12.63.38.11.6-0.12.0-2.62.60.2-2.82.92.3-0.2-2.00.8-1.50.70.0
Locomotion velocity, session 20.60.73.4-1.3-0.7-0.60.5-0.5-0.70.5-0.5-0.5-1.80.8-1.00.8-0.0-0.6
Locomotion distance, session 20.60.82.2-0.2-1.00.0-1.11.1-0.8-1.41.50.6-1.2-0.4-0.6-0.8-0.5-0.1
Locomotion velocity, session 31.82.15.80.62.01.2-0.90.92.0-1.61.61.40.2-1.21.81.22.40.9
Locomotion distance, session 30.60.72.2-0.11.50.00.2-0.21.3-0.20.20.30.2-0.21.01.51.31.0
Stereotopy head waving bouts, day 30.40.50.80.60.60.6-0.80.80.7-0.90.90.80.2-0.70.70.00.70.5
Stereotopy head waving duration, day 30.81.02.80.6-0.11.1-1.41.4-0.1-1.71.71.2-0.6-0.70.2-0.60.6-0.5
Locomotion velocity, session 70.20.31.2-0.00.30.2-0.40.40.4-1.01.10.5-0.4-0.20.20.60.60.1
Locomotion distance, session 70.81.13.60.51.90.30.3-0.41.8-0.0-0.00.41.2-0.51.41.31.51.0
Stereotopy head waving bouts, day 72.12.35.12.01.51.5-1.41.41.7-0.70.61.32.1-1.81.9-0.50.82.3
Stereotopy head waving duration, day 71.72.03.51.81.01.9-1.81.81.2-1.01.01.61.1-1.81.6-0.81.01.5
Locomotion velocity, session 80.70.81.50.40.60.9-1.21.20.8-0.90.91.2-0.1-1.20.90.01.10.6
Locomotion distance, session 80.71.14.2-1.30.8-1.31.1-1.10.71.0-1.0-0.9-0.90.8-0.02.10.70.8
Degree of sensitization distance0.30.30.60.1-0.2-0.30.6-0.7-0.10.8-0.8-0.40.80.3-0.2-0.4-0.6-0.4
Degree of sensitization stereotypy1.31.45.11.51.21.0-0.90.91.30.1-0.20.71.7-1.41.5-0.40.52.3
Condit. Reinf. active minus inactive responses0.10.10.70.20.30.0-0.20.20.3-0.10.10.2-0.3-0.30.30.10.50.8
Condit. Reinf. active-inactive response ratio0.10.10.3-0.10.0-0.3-0.10.10.1-0.30.3-0.1-0.5-0.0-0.10.20.20.4
Condit. Reinf. active responses0.30.40.80.80.20.7-0.70.80.2-0.40.40.80.1-0.90.5-0.70.40.7
Condit. Reinf. inactive responses0.50.52.00.9-0.41.0-1.01.0-0.4-0.40.41.00.3-0.90.2-1.4-0.3-0.0
Incentive salience index mean0.10.20.60.30.10.1-0.60.60.1-0.50.50.4-0.3-0.50.2-0.20.20.8
Condit. Reinf. lever presses0.91.22.61.1-0.10.9-1.61.6-0.1-1.31.41.30.7-1.30.5-1.5-0.30.6
Time in familiar zone, hab. session 10.60.51.61.00.30.7-0.70.70.3-0.60.60.81.3-0.90.7-0.8-0.20.6
Time in novel zone, hab. session 10.90.91.6-1.0-0.7-1.21.0-1.0-0.70.8-0.8-1.3-0.81.2-1.10.5-0.8-0.6
Total zone transitions, hab. session 12.13.06.02.21.71.6-1.41.41.9-1.61.61.52.4-2.12.1-0.71.01.6
Total locomotion distance, hab. session 10.50.73.51.31.00.6-0.10.01.1-0.30.20.31.9-0.71.1-0.40.40.5
Locomotion velocity, hab. session 10.60.93.21.41.20.9-0.40.31.3-0.40.40.61.8-1.01.3-0.40.80.6
Time in familiar zone, hab. session 20.50.62.60.6-0.6-0.3-0.10.1-0.30.2-0.2-0.31.6-0.2-0.2-1.3-1.60.6
Time in novel zone, hab. session 20.70.72.7-0.20.40.8-0.60.50.4-0.90.90.8-1.6-0.30.30.71.6-0.8
Total zone transitions, hab. session 20.20.20.6-0.00.4-0.70.7-0.70.50.0-0.0-0.70.20.30.10.60.20.5
Total locomotion distance, hab. session 20.50.71.8-0.5-0.2-1.21.3-1.3-0.11.1-1.0-1.30.00.9-0.50.4-0.4-0.3
Locomotion velocity, hab. session 20.40.51.4-0.4-0.1-1.01.1-1.20.00.9-0.9-1.00.00.7-0.40.4-0.3-0.3
Novel to familiar place preference ratio1.21.22.4-1.6-0.2-1.21.4-1.4-0.31.3-1.2-1.2-1.21.4-0.91.4-0.2-0.4
Novelty place preference1.51.53.1-1.8-0.4-1.41.5-1.5-0.51.3-1.3-1.3-1.31.6-1.11.4-0.3-0.5
Time in novel zone, NPP test1.41.53.0-1.7-0.5-1.31.4-1.4-0.61.2-1.1-1.3-1.41.6-1.11.3-0.4-0.7
Total zone transitions, NPP test0.60.91.61.10.60.9-1.01.00.7-1.21.11.00.5-1.30.9-0.40.51.1
Total locomotion distance, NPP test0.30.51.40.40.7-0.30.7-0.70.80.8-0.9-0.51.2-0.10.50.3-0.11.1
Locomotion velocity, NPP test0.30.51.30.30.5-0.40.8-0.80.61.1-1.1-0.61.10.10.30.3-0.31.0
Pavlov. Cond. lever latency0.60.71.5-1.1-0.1-0.71.0-1.0-0.10.9-0.9-1.0-1.11.1-0.61.20.3-0.2
Pavlov. Cond. magazine entry latency0.20.31.50.50.4-0.60.4-0.40.40.2-0.1-0.41.2-0.10.30.1-0.50.9
Pavlov. Cond. change in total contacts0.10.10.50.30.0-0.50.0-0.0-0.1-0.10.1-0.10.7-0.00.0-0.1-0.60.6
Pavlov. Cond. index score0.20.31.30.90.10.0-0.30.30.1-0.40.40.21.2-0.50.4-0.7-0.50.6
Pavlov. Cond. latency score0.20.30.70.80.00.1-0.50.50.0-0.50.60.40.9-0.60.3-0.7-0.40.4
Pavlov. Cond. lever contacts0.20.21.40.4-0.4-0.4-0.10.1-0.4-0.20.3-0.00.9-0.1-0.2-0.7-1.20.4
Pavlov. Cond. magazine entry number0.20.31.9-0.7-0.40.4-0.30.3-0.4-0.0-0.00.4-1.40.1-0.40.10.4-0.9
Pavlov. Cond. intertrial magazine entries1.31.52.4-1.5-0.4-1.21.5-1.6-0.61.5-1.5-1.2-1.51.4-1.01.1-0.0-0.8
Pavlov. Cond. lever-magazine prob. diff.0.20.21.20.70.0-0.2-0.20.20.1-0.30.40.01.1-0.40.2-0.6-0.60.6
Pavlov. Cond. response bias0.30.43.30.90.3-0.30.2-0.20.4-0.10.2-0.11.8-0.30.5-0.5-0.70.7
Bone: apparent density0.50.91.71.30.60.8-1.11.10.7-1.21.20.81.0-1.10.9-0.60.40.9
Bone surface0.40.72.10.9-0.80.0-0.80.8-0.6-1.01.00.30.8-0.5-0.2-1.5-1.40.3
Bone volume0.61.02.61.3-0.30.7-1.41.4-0.0-1.61.60.80.7-1.00.4-1.3-0.40.5
Bone: connectivity density0.40.61.61.30.80.7-0.60.60.9-0.70.70.71.1-0.91.0-0.20.50.7
Bone: cortical apparent density0.81.04.01.5-0.50.7-1.01.0-0.3-0.70.70.71.6-0.90.3-2.0-1.20.4
Bone: cortical area0.81.35.7-0.2-1.9-0.9-0.10.1-1.7-0.50.6-0.70.10.6-1.4-1.4-2.4-0.5
Bone: cortical porosity0.80.93.6-0.7-1.5-0.2-0.10.1-1.5-0.30.3-0.0-0.90.5-1.2-0.9-1.1-1.9
Bone: cortical porosity2.32.55.5-1.6-2.3-1.20.9-0.9-2.30.5-0.4-1.2-1.41.6-2.2-0.6-2.0-2.3
Bone: cortical thickness0.20.31.60.1-0.5-0.60.3-0.2-0.4-0.10.1-0.70.90.3-0.4-0.6-1.30.6
Bone: cortical thickness0.40.40.90.9-0.10.7-0.80.8-0.1-0.90.90.60.8-0.50.3-0.9-0.3-0.1
Bone: cortical tissue density0.70.93.41.4-0.40.7-0.91.0-0.2-0.60.60.71.5-0.90.3-1.8-1.10.4
Bone: elastic displacement0.50.61.5-0.40.9-0.70.9-1.00.90.7-0.7-0.70.80.40.41.20.20.9
Bone: elastic work0.20.20.40.4-0.30.4-0.60.7-0.3-0.60.60.40.4-0.30.0-0.7-0.5-0.2
Bone: endosteal estimation0.40.92.7-0.2-1.6-0.1-0.60.7-1.6-0.60.60.1-0.90.2-1.2-1.2-1.5-0.8
Bone: endosteal perimeter0.71.34.0-0.4-2.0-0.7-0.20.2-2.0-0.50.5-0.3-0.70.5-1.6-1.4-2.0-1.4
Bone: final force0.50.82.4-0.6-1.4-0.70.2-0.1-1.50.2-0.2-0.8-0.60.7-1.3-0.7-1.5-0.5
Bone: final moment0.50.82.5-0.6-1.5-0.70.1-0.0-1.50.1-0.0-0.6-0.60.7-1.3-0.8-1.6-0.6
Bone: marrow area0.40.92.7-0.1-1.6-0.1-0.60.7-1.7-0.60.60.1-0.80.2-1.2-1.3-1.5-0.8
Bone: maximum diameter2.03.711.6-0.9-3.3-1.4-0.10.1-3.1-0.80.9-0.9-1.01.2-2.7-2.1-3.4-2.2
Bone: maximum force0.81.45.3-0.4-2.0-0.80.10.0-2.0-0.20.2-0.8-0.40.8-1.6-1.4-2.3-1.0
Bone: maximum moment0.91.55.3-0.5-2.1-0.8-0.10.1-2.1-0.40.4-0.6-0.50.7-1.7-1.4-2.3-1.1
Bone: minimum diameter0.91.65.7-0.5-2.2-1.1-0.00.1-2.1-0.40.5-0.8-0.60.7-1.8-1.4-2.4-1.0
Bone: periosteal estimation0.91.85.8-0.5-2.3-0.8-0.30.4-2.3-0.60.7-0.5-0.90.7-1.8-1.6-2.4-1.1
Bone: periosteal perimeter0.71.24.8-0.5-1.8-1.00.1-0.1-1.7-0.40.4-0.8-0.20.7-1.5-1.2-2.2-0.9
Bone: post-yield work0.81.14.00.7-1.50.5-1.21.2-1.3-1.01.00.60.0-0.4-0.7-2.0-1.4-0.8
Bone: stiffness2.43.710.2-1.3-3.2-1.50.5-0.4-3.20.1-0.0-1.3-1.81.7-2.8-1.5-2.8-2.4
Bone: tissue strength1.11.12.91.1-0.00.7-1.31.30.1-1.71.71.01.0-1.10.5-1.3-0.40.5
Bone: trabecular number0.91.43.41.81.01.1-1.21.21.1-1.31.21.01.5-1.31.4-0.60.71.0
Bone: trabecular spacing0.71.02.4-1.3-1.3-0.90.6-0.5-1.30.7-0.6-0.8-1.51.0-1.4-0.1-1.0-0.6
Bone: trabecular thickness0.20.30.80.4-0.10.8-0.80.9-0.0-0.70.70.7-0.2-0.60.2-0.40.30.1
Bone: trabecular tissue density0.60.81.8-0.9-0.4-1.01.3-1.3-0.41.2-1.2-1.10.20.8-0.70.3-0.90.0
Breakpoint value in progressive ratio session0.70.82.0-1.00.4-1.11.0-1.00.51.2-1.2-0.9-0.60.8-0.21.40.40.5
Distance traveled before self-admin2.42.65.01.91.42.2-1.71.71.5-1.11.02.01.4-2.21.9-0.81.70.9
Distance traveled after self-admin1.41.64.81.41.22.2-1.21.21.5-0.10.11.51.2-1.41.5-0.21.30.8
Delta time in closed arm before/after self-admin0.90.81.81.30.11.2-1.11.10.1-0.80.70.91.1-1.00.6-1.3-0.30.7
Delta time in open arm before/after self-admin0.80.71.5-1.1-1.0-0.90.8-0.8-1.00.3-0.2-0.8-1.21.0-1.10.2-0.5-1.1
Diff in mean of infusions in LGA sessions0.20.20.30.40.40.3-0.50.50.5-0.50.50.50.1-0.40.40.00.40.6
Extinction: sum of active levers before priming0.10.10.3-0.2-0.0-0.1-0.30.3-0.0-0.40.40.4-0.5-0.2-0.00.20.10.5
Active lever presses in extinction session 60.90.83.90.51.11.0-0.70.71.2-0.80.70.8-0.4-0.71.00.62.0-0.1
Delta distance traveled before/after self-admin0.30.31.5-0.0-0.30.00.5-0.5-0.11.2-1.2-0.50.40.5-0.30.1-0.7-0.1
Delta ambulatory time before/after self-admin1.21.33.5-1.1-0.4-0.81.5-1.5-0.31.9-1.8-1.4-0.51.4-0.91.0-0.6-0.6
Time in closed arm before self-admin0.50.50.9-0.8-0.4-0.60.9-0.9-0.50.9-0.9-0.8-0.70.9-0.70.6-0.3-0.8
Time in closed arm after self-admin0.20.31.40.9-0.10.4-0.20.2-0.10.0-0.1-0.11.2-0.20.2-0.8-0.80.2
Time in open arm before self-admin0.70.71.91.00.50.8-1.01.00.7-0.40.41.01.4-1.00.9-0.70.00.9
Time in open arm after self-admin0.30.31.0-0.7-0.80.0-0.30.3-0.8-0.50.60.3-1.00.2-0.7-0.3-0.2-0.8
Sum of active levers in priming session hrs 5-60.60.61.30.90.50.5-0.80.80.9-1.11.10.80.4-0.90.8-0.30.60.9
Time to tail flick, vehicle, before self-admin2.32.45.61.80.71.3-1.71.70.9-2.42.31.91.4-1.81.3-0.90.30.9
Time to tail flick, vehicle, after self-admin1.01.13.11.60.61.0-1.01.00.9-0.80.71.01.8-1.41.1-0.70.00.8
Time to tail flick, test, before self-admin0.60.61.10.90.80.8-0.80.80.6-0.80.81.00.4-1.10.9-0.20.80.9
Time to tail flick, test, after self-admin1.41.43.01.10.51.5-1.61.60.6-1.61.51.70.0-1.50.9-0.61.10.4
Delta time to tail flick, vehicle, before/after SA0.80.81.5-1.0-0.4-0.61.0-1.0-0.51.2-1.2-1.1-0.91.0-0.80.7-0.0-0.6
Delta time to tail flick, test, before/after SA0.20.20.40.10.10.5-0.60.60.3-0.60.60.6-0.3-0.40.2-0.10.6-0.2
Ambulatory time before self-admin1.71.73.41.41.21.8-1.51.41.3-1.00.91.60.9-1.71.6-0.61.60.6
Ambulatory time after self-admin0.40.41.50.50.61.2-0.30.30.90.5-0.50.60.2-0.40.60.21.1-0.4
Total heroin consumption0.10.20.30.00.20.3-0.30.40.3-0.50.50.5-0.6-0.40.20.20.60.4
Area under the delay curve0.20.21.2-0.1-0.10.2-0.50.5-0.1-0.50.50.5-0.7-0.20.1-0.10.9-1.1
Delay disc. indifference point, 0s delay0.20.21.0-0.20.8-0.20.1-0.10.6-0.40.40.2-0.10.20.51.00.90.1
Delay disc. indifference point, 16s delay0.50.61.30.80.50.7-0.90.90.5-0.60.60.90.3-1.00.8-0.51.2-0.2
Delay disc. indifference point, 2s delay0.50.61.40.6-0.50.9-1.11.1-0.2-0.70.70.80.2-0.70.1-1.2-0.1-1.0
Delay disc. indifference point, 24s delay0.60.61.1-0.1-1.00.4-1.01.0-1.0-0.80.80.6-0.8-0.3-0.5-1.1-0.3-1.0
Delay disc. indifference point, 4s delay0.20.21.0-0.10.30.8-0.30.30.30.2-0.20.8-0.5-0.20.30.21.0-0.7
Delay disc. indifference point, 8s delay0.60.62.8-0.3-0.10.0-0.50.5-0.2-0.91.00.4-1.40.1-0.10.21.4-1.7
Delay discount exponential model param0.30.31.50.10.3-0.20.5-0.50.30.4-0.5-0.50.80.10.10.3-0.61.2
Delay discount hyperbolic model param0.20.21.50.00.2-0.40.5-0.50.20.4-0.4-0.60.60.2-0.00.3-0.71.2
Fecal boli incidents, locomotor time 11.01.12.21.10.81.5-1.21.20.8-1.00.91.50.5-1.21.1-0.51.10.2
Change in fecal boli incidents, locomotor task0.50.51.30.11.10.30.4-0.41.00.8-0.7-0.00.7-0.30.81.01.00.6
Time >=10cm from walls, locomotor time 11.91.94.7-0.9-2.0-1.10.5-0.4-2.1-0.10.1-0.9-0.91.5-1.9-0.8-2.2-2.0
Bouts of movement, locomotor time 11.01.12.6-1.20.1-1.11.3-1.3-0.21.1-1.1-1.3-1.31.0-0.61.60.7-0.1
Total resting periods, locomotor time 10.91.03.0-1.10.3-1.11.3-1.30.11.0-1.0-1.3-1.10.9-0.41.70.70.1
Rest time, locomotor task time 10.40.41.60.20.90.6-0.10.20.9-0.40.40.2-0.0-0.50.70.91.30.4
Distance moved, locomotor task time 11.31.57.70.1-1.7-0.80.3-0.3-1.60.7-0.7-0.81.00.6-1.2-1.9-2.8-0.4
Vertical activity count, locomotor time 10.50.52.00.1-1.10.1-0.30.3-1.10.3-0.2-0.10.50.3-0.7-1.4-1.4-0.6
Time >=10cm from walls, locomotor time 20.20.20.70.10.20.6-0.80.80.3-0.40.40.6-0.2-0.10.20.10.1-0.5
Bouts of movement, locomotor time 22.12.38.9-2.0-1.9-1.50.3-0.3-1.9-0.70.8-0.9-3.01.3-2.00.0-0.7-2.0
Total resting periods, locomotor time 22.22.39.7-2.0-1.8-1.20.1-0.0-2.0-0.91.0-0.6-3.11.2-2.0-0.0-0.4-2.2
Rest time, locomotor task time 20.60.73.0-1.0-0.6-0.20.9-0.9-0.90.5-0.5-0.3-1.20.7-0.80.40.4-1.7
Distance moved, locomotor task time 20.60.73.81.00.8-0.2-0.30.30.90.1-0.1-0.21.9-0.50.9-0.4-0.51.6
Vertical activity count, locomotor time 20.20.21.00.30.5-0.30.0-0.10.60.3-0.3-0.50.90.10.30.1-0.31.0
Weight adjusted by age0.30.31.3-0.9-0.1-0.20.5-0.5-0.00.7-0.6-0.4-1.20.5-0.40.80.4-0.3
Seeking ratio, delayed vs. immediate footshock0.30.40.8-0.7-0.7-0.70.4-0.4-0.60.2-0.1-0.7-0.40.7-0.8-0.1-0.8-0.9
Locomotion in novel chamber0.81.03.91.41.10.3-0.50.51.50.0-0.10.22.0-1.01.3-0.30.41.3
Locomotion in novel chamber post-restriction0.40.51.3-0.30.6-0.10.9-0.80.91.0-1.0-0.6-0.50.30.31.01.10.2
Progressive ratio0.20.20.9-0.3-0.6-0.4-0.30.3-0.4-0.50.5-0.3-0.10.1-0.5-0.3-1.00.3
Food seeking constrained by brief footshock2.63.17.31.70.72.7-2.42.30.9-1.91.92.50.2-2.21.4-1.21.50.5
Seeking ratio, punishment vs. effort1.11.44.01.50.92.0-1.21.10.8-0.40.31.80.6-1.61.3-0.81.40.3
Run reversals in cocaine runway, females0.10.10.7-0.3-0.4-0.10.0-0.0-0.40.2-0.2-0.3-0.50.3-0.4-0.10.0-0.8
Run reversals in cocaine runway, males0.20.20.4-0.2-0.5-0.30.0-0.0-0.5-0.30.4-0.6-0.60.6-0.6-0.1-0.2-0.7
Latency to leave start box in cocaine runway1.92.14.21.70.81.8-1.61.60.9-2.12.01.90.8-1.51.3-0.91.2-0.3
Latency to leave start box in cocaine runway, F1.61.73.31.81.41.8-0.90.91.5-0.70.61.51.7-1.51.8-0.41.50.2
Latency to leave start box in cocaine runway, M0.90.94.00.5-0.60.4-1.11.1-0.5-2.02.00.7-0.3-0.4-0.2-0.9-0.3-0.7
Cd content in liver0.40.41.50.70.60.6-0.30.30.8-0.30.20.21.0-0.70.8-0.20.31.2
Co content in liver1.61.94.20.8-1.21.7-2.02.0-1.0-1.41.51.8-0.5-1.1-0.2-2.0-0.4-1.3
Cu content in liver0.10.10.4-0.0-0.60.0-0.10.2-0.60.1-0.0-0.2-0.30.1-0.4-0.6-0.4-0.3
Fe content in liver0.40.51.11.00.81.0-0.50.60.8-0.30.30.60.9-0.61.0-0.10.80.5
K content in liver1.61.62.9-1.5-1.4-1.71.1-1.1-1.40.2-0.1-1.5-1.21.6-1.70.3-1.4-1.1
Mg content in liver0.91.02.7-1.1-0.1-1.61.4-1.4-0.20.7-0.7-1.6-0.11.2-0.71.0-0.70.4
Mn content in liver0.81.01.8-1.0-0.6-1.31.3-1.3-0.51.2-1.2-1.3-0.41.1-0.90.5-0.90.2
Na content in liver2.12.28.1-1.90.8-2.41.7-1.80.60.5-0.5-1.8-1.21.5-0.42.80.60.9
Rb content in liver0.50.72.21.0-0.40.7-1.11.1-0.4-1.41.50.8-0.1-0.4-0.0-0.8-0.2-0.4
Se content in liver2.32.85.0-0.71.8-1.42.2-2.21.72.1-2.2-1.81.31.00.82.20.81.7
Sr content in liver0.10.10.20.20.50.10.2-0.20.50.2-0.20.10.2-0.10.40.30.50.2
Zn content in liver0.20.20.7-0.40.2-0.50.8-0.80.10.6-0.6-0.7-0.10.5-0.10.50.1-0.0