Hub : Genes

Slc6a11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000005697 0.13 0.1 1.6e-03 0.01 0.06 0.04 0.03 5.6e-02 6.6e-04 2.3e-03 7.1e-03
2 BLA mRNA stability ENSRNOG00000005697 0.31 0.13 6.5e-13 0.21 0.23 0.2 0.26 2.6e-11 8.0e-13 9.0e-11 4.4e-14
3 Brain gene expression ENSRNOG00000005697 0.12 0.07 1.1e-05 0.06 0.05 0.05 0.05 4.6e-06 1.1e-05 1.2e-05 4.4e-05
4 Brain mRNA stability ENSRNOG00000005697 0.06 0.04 1.9e-04 0.04 0.04 0.03 0.03 7.9e-05 3.3e-04 1.5e-03 1.8e-03
5 Eye gene expression ENSRNOG00000005697 0.26 0.14 9.9e-03 0.11 0.03 -0 0.05 8.6e-03 1.2e-01 3.8e-01 5.7e-02
6 NAcc mRNA stability ENSRNOG00000005697 0.1 0.05 3.9e-09 0.07 0.08 0.09 0.08 4.0e-06 1.8e-06 5.7e-07 1.7e-06
7 OFC mRNA stability ENSRNOG00000005697 0.2 0.09 8.2e-04 0.12 0.14 0.12 0.09 8.3e-04 3.3e-04 8.4e-04 3.6e-03
8 PL gene expression ENSRNOG00000005697 0.07 0.05 1.1e-03 0.03 0.03 0.02 0.02 3.4e-03 4.1e-03 1.1e-02 1.6e-02
9 PL mRNA stability ENSRNOG00000005697 0.09 0.05 9.5e-06 0.08 0.06 0.07 0.07 1.2e-06 5.1e-05 5.0e-06 4.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.72.14.01.01.21.42.0-1.71.71.41.11.2
BMI without tail0.20.30.80.30.70.90.7-0.50.80.2-0.10.5
Body weight0.83.65.0-0.01.72.11.6-2.12.22.22.02.0
Epididymis fat weight0.30.81.5-1.20.71.1-0.5-0.90.71.10.01.0
Glucose2.64.06.70.82.62.41.5-2.62.21.61.12.3
Heart weight0.40.61.90.60.90.71.4-0.50.80.50.10.8
Left kidney weight1.44.15.5-1.2-2.0-2.0-1.82.1-2.4-2.4-2.2-1.9
Right kidney weight1.33.76.5-2.5-2.1-1.5-2.51.6-2.1-1.5-1.8-1.3
Tail length0.10.21.0-0.70.20.3-1.00.1-0.2-0.3-0.50.2
Length with tail0.20.81.7-1.30.70.9-0.6-0.80.60.91.11.0
Length without tail0.20.52.5-1.6-0.5-0.1-0.4-0.2-0.10.70.90.1
Liver weight, left0.30.41.9-1.40.20.4-1.2-0.5-0.10.1-0.00.3
Liver weight, right0.81.32.8-1.7-1.2-0.9-1.70.6-1.0-0.6-0.9-1.0
Parametrial fat weight0.50.92.9-0.80.61.20.2-1.70.91.2-0.01.0
Retroperitoneal fat weight0.00.10.4-0.7-0.50.1-0.50.2-0.10.4-0.40.0
Intraocular pressure0.30.41.2-0.20.81.10.3-0.90.50.2-0.60.8
Extensor digitorum longus weight4.618.636.62.63.63.76.0-3.95.04.84.33.9
Soleus weight0.72.15.01.51.31.02.2-1.21.71.21.41.0
Tibialis anterior weight1.13.97.3-1.41.62.21.3-2.42.12.71.62.1
Tibia length0.41.02.4-1.0-1.0-0.6-1.30.6-1.2-0.7-1.5-0.5
Number of licking bursts0.20.20.7-0.80.50.3-0.6-0.60.20.10.20.4
Food consumed during 24 hour testing period0.30.31.4-1.2-0.30.20.0-0.5-0.10.1-1.00.3
Times rat made contact with spout0.10.10.8-0.1-0.1-0.0-0.3-0.2-0.2-0.2-0.90.1
Mean time between licks in bursts1.01.42.5-0.21.01.40.7-1.41.21.60.91.4
Mean num. licks in bursts0.60.71.50.8-1.0-0.80.10.9-0.8-0.7-1.2-0.8
Std. dev. time between licks in bursts0.30.41.30.9-0.3-0.40.00.6-0.5-0.6-1.1-0.3
Water consumed over 24 hours0.10.10.2-0.3-0.10.20.2-0.20.30.5-0.10.3
Indifference point 0 sec0.30.50.90.21.00.8-0.0-0.50.60.50.90.9
Indifference point AUC2.22.66.3-0.8-1.4-1.3-1.61.4-1.6-1.9-2.5-1.4
Indifference point function ln k2.12.98.70.71.21.21.8-1.41.82.03.01.3
Indifference point function log k2.12.98.70.71.21.21.8-1.41.82.03.01.3
Delay discounting total patch changes 0 sec0.30.51.10.31.00.90.2-0.60.60.61.10.9
Delay discounting total patch changes 12 sec0.81.13.20.5-0.1-0.4-1.20.7-1.1-1.6-1.8-0.4
Delay discounting total patch changes 18 sec0.70.92.0-0.8-0.4-0.5-1.40.6-1.0-1.3-1.3-0.5
Delay discounting total patch changes 24 sec0.20.31.60.1-0.2-0.1-0.30.3-0.3-0.6-1.3-0.2
Delay discounting total patch changes 6 sec0.50.81.80.81.31.10.5-0.90.90.50.41.2
Delay discounting time to switch 0 sec1.11.62.9-0.11.11.31.1-1.01.51.71.61.3
Delay discounting water rate 0 sec1.52.44.31.6-1.2-1.9-0.51.5-1.5-2.1-1.0-1.9
Delay discounting water rate 12 sec0.00.00.30.00.00.0-0.1-0.60.10.10.20.0
Delay discounting water rate 18 sec0.20.31.81.3-0.0-0.10.60.10.1-0.20.1-0.3
Delay discounting water rate 24 sec0.30.51.00.3-0.6-0.8-0.20.3-0.9-1.0-0.1-0.9
Delay discounting water rate 6 sec0.10.20.50.3-0.4-0.6-0.10.1-0.6-0.7-0.1-0.6
Locomotor activity0.30.51.5-0.60.30.0-1.2-0.0-0.6-1.0-1.1-0.0
Locomotor testing distance1.01.74.30.2-0.4-1.0-1.50.6-1.5-2.1-2.1-0.9
Locomotor testing rearing1.21.95.2-1.3-0.6-0.6-2.20.3-1.5-1.5-2.3-0.6
Light reinforcement 10.30.52.3-0.8-0.7-0.5-1.50.3-0.8-0.3-0.5-0.3
Light reinforcement 20.71.02.4-1.40.20.90.2-0.60.81.61.21.0
Reaction time number correct0.71.12.50.10.80.80.9-0.91.21.41.60.9
Reaction time mean minus median0.91.22.10.7-1.0-1.2-0.21.4-1.1-1.3-1.1-1.4
Reaction time mean minus median AUC1.01.32.11.2-0.9-1.2-0.31.4-1.1-1.3-1.0-1.4
Reaction time num false alarms0.40.62.11.40.40.11.4-0.20.50.10.90.2
Reaction time num false alarms AUC0.30.41.71.30.4-0.01.1-0.10.3-0.10.60.1
Reaction time trials correct on left0.71.12.50.10.80.80.9-0.91.21.41.60.9
Reaction time trials on left0.60.92.20.10.70.70.9-0.81.11.31.50.8
Reaction time mean1.92.66.2-0.0-1.7-1.4-1.11.6-1.7-1.6-2.5-1.7
Reaction time mean AUC1.72.24.90.3-1.5-1.4-1.01.6-1.6-1.5-2.2-1.6
Median of all reaction times1.52.06.0-0.2-1.4-1.1-1.11.3-1.4-1.3-2.4-1.4
Reaction time omissions2.23.04.50.3-1.6-1.9-0.92.0-1.9-2.1-2.0-2.0
Reaction time false alarm rate0.40.51.31.0-0.4-0.80.20.7-0.7-1.1-0.4-0.7
Reaction time premature initiation rate2.02.67.6-0.5-1.9-1.4-1.31.3-1.7-1.5-2.8-1.4
Reaction time premature initiations0.91.33.5-0.7-1.5-1.0-1.00.8-1.2-0.9-1.9-1.0
Std. dev. reaction times3.44.67.01.0-2.1-2.4-0.72.5-2.2-2.5-2.5-2.7
Reaction time trials completed0.60.92.20.10.70.70.9-0.81.11.31.50.8
Reaction time trials AUC0.60.92.10.20.60.70.9-0.81.11.31.50.8
Social response proportion1.71.87.4-2.7-1.0-0.6-2.00.2-1.2-0.7-1.2-0.4
Social responses2.32.94.8-0.2-1.6-1.9-1.51.5-2.0-2.2-1.9-1.6
Social time0.70.92.2-1.1-1.5-0.8-0.50.6-0.9-0.4-1.3-0.9
Conditioned locomotion2.42.95.7-0.52.42.00.4-1.91.71.31.92.0
Cocaine response after cond. corrected2.62.95.3-0.9-1.3-1.5-1.81.4-2.0-2.3-2.2-1.5
Cocaine response after cond. not corrected5.46.09.0-1.5-2.2-2.2-2.52.1-2.9-2.9-3.0-2.3
Cocaine response before conditioning1.11.32.4-0.8-1.5-1.1-1.01.2-1.2-0.8-1.1-1.2
Saline control response1.31.75.8-2.4-0.6-0.2-2.2-0.2-1.1-0.6-1.7-0.2
Condit. Reinf. active minus inactive responses1.51.83.4-0.0-1.3-1.1-1.41.4-1.6-1.4-1.8-1.3
Condit. Reinf. active-inactive response ratio0.91.02.10.7-1.0-0.9-0.31.1-1.1-1.1-1.5-1.0
Condit. Reinf. active responses0.81.12.3-0.1-0.8-0.8-1.31.0-1.3-1.3-1.5-1.0
Condit. Reinf. inactive responses0.30.41.3-1.20.60.6-1.0-0.60.10.00.10.4
Condit. Reinf. lever presses0.20.20.6-0.8-0.20.0-0.60.2-0.4-0.5-0.8-0.1
Condit. Reinf. lever reinforcers received1.31.83.6-0.4-1.1-0.9-1.71.1-1.6-1.5-1.9-1.1
Pavlov. Cond. lever latency0.20.21.01.0-0.4-0.60.40.4-0.00.10.2-0.5
Pavlov. Cond. magazine entry latency0.30.30.9-0.6-0.5-0.2-0.20.6-0.5-0.6-1.0-0.2
Pavlov. Cond. change in total contacts0.81.12.3-0.5-0.6-0.7-1.01.0-1.3-1.5-1.4-0.8
Pavlov. Cond. index score0.20.30.9-0.6-0.2-0.2-0.40.5-0.7-0.9-1.0-0.2
Pavlov. Cond. latency score0.20.30.6-0.6-0.4-0.3-0.30.6-0.7-0.8-0.8-0.3
Pavlov. Cond. lever contacts0.10.10.3-0.30.50.3-0.2-0.1-0.1-0.5-0.30.2
Pavlov. Cond. magazine entry number1.01.32.30.41.11.00.7-1.41.31.31.50.9
Pavlov. Cond. intertrial magazine entries0.10.20.5-0.3-0.7-0.4-0.70.2-0.30.30.1-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.41.1-0.4-0.4-0.3-0.40.6-0.8-1.0-1.0-0.3
Pavlov. Cond. response bias0.10.10.3-0.10.50.4-0.1-0.1-0.1-0.5-0.50.3
Conditioned reinforcement - actives1.01.02.00.90.40.71.3-1.40.81.31.00.9
Conditioned reinforcement - inactives0.10.10.3-0.2-0.5-0.1-0.5-0.5-0.30.3-0.5-0.1
Conditioned locomotion0.40.51.8-0.10.10.40.2-1.30.21.10.70.7
Intermittent access intake day 1-15 change1.21.23.31.80.70.41.5-1.30.90.80.90.4
Intermittent access intake escalation0.70.72.81.70.40.11.1-0.80.60.60.70.1
Intermittent access intake escalation 21.11.13.31.80.30.31.7-1.11.01.00.60.2
Intermitt. access day 1 inactive lever presses1.41.52.5-0.7-1.6-1.5-1.10.9-1.3-1.2-1.2-1.4
Intermitt. access day 15 inactive lever presses0.70.82.30.4-0.4-0.6-0.80.8-0.9-1.3-1.5-0.6
Intermitt. access escalation Index1.11.03.3-1.21.11.0-0.2-0.31.00.71.80.9
Intermittent access day 1 total infusions0.60.71.8-0.30.60.9-0.0-1.40.61.10.61.1
Intermittent access day 15 total infusions1.82.04.31.21.21.01.1-2.11.31.61.51.3
Intermittent access terminal intake (last 3 days)2.62.85.51.41.31.31.6-2.31.71.91.71.4
Intermittent access total infusions1.71.94.80.41.21.40.6-2.21.21.61.41.5
Intermittent access day 1 locomotion1.31.32.60.20.91.20.9-1.61.11.50.81.4
Intermittent access day 15 total locomotion1.11.12.01.40.40.61.1-1.31.11.31.01.0
Intermittent access total locomotion1.01.22.21.10.60.81.1-1.51.01.31.01.1
Intermittent access standard deviation0.20.20.80.9-0.7-0.5-0.1-0.1-0.30.3-0.2-0.5
Cocaine induced anxiety0.30.30.7-0.2-0.4-0.7-0.30.7-0.5-0.8-0.0-0.7
Post-drug Anxiety3.13.45.6-0.4-1.8-2.0-1.52.4-2.0-2.2-1.7-2.0
Baseline Anxiety1.31.32.4-0.8-1.2-0.9-1.41.1-1.4-0.8-1.6-0.9
Lifetime Intake1.61.84.3-0.01.01.30.6-2.11.21.81.51.5
Incentive Sensitization - Responses0.80.82.60.40.60.70.9-1.60.90.90.60.7
Incentive Sensitization - Breakpoint0.90.92.90.50.70.81.0-1.71.01.00.70.8
Progressive ratio test 1 active lever presses0.50.51.8-0.90.40.6-0.2-1.40.40.80.50.8
Progressive ratio test 1 breakpoint0.70.72.4-0.70.40.70.1-1.60.51.00.70.9
Progressive ratio test 1 inactive lever presses0.10.10.3-0.5-0.4-0.2-0.40.2-0.20.10.1-0.0
Progressive ratio test 2 active lever presses1.11.23.20.50.80.90.9-1.81.01.21.01.1
Progressive ratio test 2 breakpoint1.11.33.40.30.81.00.9-1.81.11.30.91.3
Progressive ratio test 2 inactive lever presses0.10.10.40.1-0.00.2-0.1-0.60.10.4-0.30.4
Total sessions with >9 infusions1.01.15.3-2.3-0.20.4-1.4-1.3-0.20.8-0.00.3
Short access day 1 total inactive lever presses0.60.74.7-2.2-0.5-0.0-1.0-0.0-0.40.3-0.20.2
Short access day 10 total inactive lever presses1.51.72.40.2-1.3-1.4-1.21.5-1.3-1.5-1.6-1.3
Short access day 1 total infusions1.01.12.1-1.40.31.0-0.0-1.40.61.51.11.0
Short access day 10 total infusions0.70.81.8-0.00.40.90.4-1.30.81.40.90.9
Short access total infusions0.91.02.2-1.20.20.9-0.2-1.50.51.50.91.0
Short access day 1 locomotion2.93.05.70.31.31.71.4-2.31.72.41.91.9
Short access day 10 total locomotion0.20.30.70.0-0.9-0.5-0.4-0.1-0.5-0.1-0.8-0.4
Short access total locomotion0.20.20.6-0.5-0.30.1-0.3-0.8-0.10.7-0.20.4
Compulsive drug intake3.83.86.70.8-1.8-2.5-0.72.5-1.8-2.4-1.2-2.6
One hour access (0.3 mA shock)0.70.92.31.50.20.20.8-1.20.71.01.30.3
One hour access (shock baseline)4.45.110.10.71.92.21.3-3.22.22.72.62.3
Number of responses in last shaping day4.24.26.91.41.61.82.3-2.62.12.32.02.1
Context. condit. distance diff. score2.02.46.62.61.61.12.2-1.41.51.00.61.2
Locomotion velocity, session 10.20.20.6-0.2-0.8-0.5-0.20.7-0.6-0.2-0.3-0.6
Locomotion distance, session 10.20.20.4-0.6-0.4-0.4-0.60.5-0.6-0.5-0.5-0.3
Locomotion velocity, session 21.01.22.0-1.0-1.4-1.1-1.01.2-1.2-0.7-1.0-1.1
Locomotion distance, session 20.50.62.7-1.6-0.7-0.5-1.10.5-0.7-0.4-0.3-0.4
Locomotion velocity, session 30.40.51.5-0.8-0.8-0.5-0.70.4-0.7-0.5-1.2-0.5
Locomotion distance, session 30.30.41.8-1.4-0.5-0.1-0.8-0.3-0.40.2-0.4-0.0
Stereotopy head waving bouts, day 31.62.03.2-0.4-1.7-1.7-0.71.8-1.4-1.2-1.1-1.8
Stereotopy head waving duration, day 32.53.05.00.2-2.2-2.0-0.42.1-1.8-1.6-1.9-2.1
Locomotion velocity, session 70.10.10.4-0.20.10.1-0.7-0.4-0.3-0.3-0.50.1
Locomotion distance, session 71.01.33.0-0.21.01.30.4-1.71.11.40.81.4
Stereotopy head waving bouts, day 71.92.13.0-0.3-1.6-1.7-1.51.6-1.7-1.4-0.9-1.7
Stereotopy head waving duration, day 72.53.14.5-0.2-2.0-2.1-1.52.0-1.9-1.6-1.3-2.1
Locomotion velocity, session 80.10.20.70.30.50.20.2-0.10.50.20.90.2
Locomotion distance, session 80.81.22.11.41.31.01.4-1.11.10.70.51.0
Degree of sensitization distance0.70.71.61.31.10.80.7-0.80.70.40.50.8
Degree of sensitization stereotypy0.50.50.9-0.0-0.8-0.9-0.80.8-0.8-0.7-0.0-0.9
Condit. Reinf. active minus inactive responses2.52.85.4-0.6-1.2-1.5-2.01.2-2.0-2.2-2.3-1.4
Condit. Reinf. active-inactive response ratio4.04.37.8-0.6-1.5-2.0-2.51.7-2.5-2.8-2.4-1.9
Condit. Reinf. active responses0.50.61.4-0.4-0.6-0.7-1.00.3-1.0-1.0-1.2-0.5
Condit. Reinf. inactive responses1.72.03.3-0.41.21.61.0-1.61.41.81.41.6
Incentive salience index mean3.03.66.2-0.2-1.5-2.0-1.91.6-2.2-2.5-2.4-1.8
Condit. Reinf. lever presses1.82.44.60.2-1.3-1.9-1.01.6-1.7-2.1-1.3-1.8
Time in familiar zone, hab. session 10.50.41.41.20.2-0.3-0.10.3-0.5-1.1-0.8-0.3
Time in novel zone, hab. session 10.20.20.7-0.5-0.8-0.6-0.10.5-0.20.20.1-0.5
Total zone transitions, hab. session 10.40.61.8-1.30.30.2-0.9-0.2-0.5-0.8-1.20.3
Total locomotion distance, hab. session 10.10.20.5-0.70.50.5-0.0-0.30.1-0.2-0.50.6
Locomotion velocity, hab. session 10.10.20.8-0.90.40.4-0.2-0.20.0-0.2-0.50.5
Time in familiar zone, hab. session 20.10.10.20.20.40.3-0.2-0.00.20.00.40.3
Time in novel zone, hab. session 20.60.61.00.6-0.8-0.9-0.00.8-0.8-0.8-1.0-0.9
Total zone transitions, hab. session 20.70.95.0-2.2-0.50.2-1.2-0.2-0.50.1-0.90.3
Total locomotion distance, hab. session 20.60.83.8-1.9-0.7-0.2-1.30.2-0.8-0.2-0.8-0.1
Locomotion velocity, hab. session 20.60.84.5-2.1-0.7-0.1-1.20.1-0.6-0.0-0.80.0
Novel to familiar place preference ratio0.20.20.40.70.0-0.4-0.10.5-0.2-0.6-0.6-0.3
Novelty place preference0.40.41.21.1-0.2-0.60.10.8-0.3-0.7-0.7-0.6
Time in novel zone, NPP test0.40.41.71.3-0.1-0.50.20.6-0.3-0.8-0.8-0.5
Total zone transitions, NPP test0.71.03.2-0.1-1.0-0.7-0.80.9-1.2-0.9-1.8-0.7
Total locomotion distance, NPP test0.00.10.40.10.00.10.10.0-0.10.0-0.60.2
Locomotion velocity, NPP test0.00.10.3-0.2-0.3-0.0-0.10.3-0.30.0-0.50.0
Pavlov. Cond. lever latency0.10.10.30.3-0.2-0.10.10.50.10.30.3-0.1
Pavlov. Cond. magazine entry latency0.50.62.20.2-0.2-0.8-0.80.5-1.0-1.5-0.6-0.7
Pavlov. Cond. change in total contacts0.10.10.2-0.00.1-0.3-0.10.1-0.2-0.50.1-0.3
Pavlov. Cond. index score0.10.10.70.10.3-0.2-0.3-0.4-0.4-0.8-0.2-0.1
Pavlov. Cond. latency score0.20.20.9-0.00.1-0.4-0.4-0.2-0.6-1.0-0.6-0.3
Pavlov. Cond. lever contacts0.10.10.3-0.30.20.0-0.2-0.6-0.2-0.4-0.20.1
Pavlov. Cond. magazine entry number0.60.72.4-0.50.10.90.8-0.51.01.50.50.8
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.40.10.70.6-0.80.71.10.10.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.10.3-0.1-0.4-0.4-0.3-0.7-0.2-0.1
Pavlov. Cond. response bias0.30.41.30.0-0.1-0.7-0.70.2-0.8-1.1-0.2-0.6
Bone: apparent density1.93.14.8-1.01.92.0-0.3-1.91.72.02.22.0
Bone surface0.50.91.6-0.71.11.3-0.7-0.90.81.00.71.1
Bone volume1.11.82.7-0.31.61.6-0.2-1.41.41.41.61.5
Bone: connectivity density1.01.62.6-0.81.21.4-0.1-1.21.21.61.61.4
Bone: cortical apparent density0.30.40.60.5-0.7-0.8-0.30.8-0.6-0.5-0.3-0.8
Bone: cortical area0.00.10.30.30.10.2-0.1-0.0-0.1-0.1-0.60.0
Bone: cortical porosity1.51.74.02.0-0.8-1.40.31.7-0.8-1.4-0.8-1.4
Bone: cortical porosity1.11.23.61.9-0.7-1.10.51.4-0.5-1.0-0.8-1.1
Bone: cortical thickness0.50.81.51.2-0.7-0.80.00.9-0.7-0.9-1.1-0.9
Bone: cortical thickness0.10.20.40.2-0.3-0.3-0.40.4-0.5-0.6-0.7-0.2
Bone: cortical tissue density0.30.30.60.5-0.7-0.8-0.20.7-0.6-0.5-0.2-0.7
Bone: elastic displacement1.11.32.5-1.01.31.5-0.0-1.41.01.00.41.6
Bone: elastic work1.52.03.3-0.91.41.80.5-1.61.51.60.81.8
Bone: endosteal estimation0.40.91.4-0.31.01.20.3-1.01.11.20.91.1
Bone: endosteal perimeter0.61.33.6-1.91.01.3-0.8-1.20.60.90.51.3
Bone: final force0.30.53.31.8-0.0-0.11.00.20.2-0.0-0.5-0.2
Bone: final moment0.30.53.21.80.30.11.0-0.00.50.2-0.20.1
Bone: marrow area0.40.81.3-0.41.01.10.2-1.01.01.10.81.0
Bone: maximum diameter0.20.42.2-1.5-0.00.4-1.1-0.3-0.20.2-0.10.2
Bone: maximum force0.50.92.11.40.70.71.3-0.61.11.10.60.7
Bone: maximum moment0.71.12.11.40.90.91.3-0.81.21.20.80.9
Bone: minimum diameter0.50.91.20.80.81.01.1-0.91.11.10.71.0
Bone: periosteal estimation0.20.40.8-0.10.70.90.0-0.70.70.80.40.7
Bone: periosteal perimeter0.30.52.5-1.6-0.00.3-1.2-0.2-0.3-0.0-0.40.2
Bone: post-yield work0.10.20.3-0.00.50.6-0.1-0.50.40.50.20.6
Bone: stiffness0.50.91.51.00.70.81.0-0.51.01.21.10.7
Bone: tissue strength0.60.61.5-1.20.50.8-0.9-0.70.40.90.60.7
Bone: trabecular number0.91.51.9-1.41.11.4-0.8-1.20.91.41.31.3
Bone: trabecular spacing0.20.20.50.7-0.2-0.50.50.3-0.2-0.6-0.5-0.4
Bone: trabecular thickness2.42.94.3-1.11.82.00.1-2.01.71.91.92.1
Bone: trabecular tissue density1.31.83.9-1.5-1.4-0.7-1.90.8-1.5-0.9-2.0-0.9
Breakpoint value in progressive ratio session8.49.316.9-0.92.43.42.1-3.13.34.13.73.2
Distance traveled before self-admin1.51.64.5-0.8-1.2-0.8-1.80.8-1.4-1.0-2.1-0.9
Distance traveled after self-admin2.02.23.7-0.1-1.8-1.7-0.81.4-1.6-1.5-1.9-1.5
Delta time in closed arm before/after self-admin0.30.21.91.4-0.3-0.20.20.4-0.10.10.1-0.3
Delta time in open arm before/after self-admin0.10.10.7-0.8-0.2-0.1-0.00.30.1-0.10.3-0.2
Diff in mean of infusions in LGA sessions2.02.23.6-1.31.81.9-0.2-1.81.31.40.91.9
Extinction: sum of active levers before priming0.60.61.9-0.60.50.80.1-0.60.71.21.40.5
Active lever presses in extinction session 63.23.15.21.11.31.82.2-1.61.92.31.61.7
Delta distance traveled before/after self-admin0.20.20.70.5-0.0-0.40.8-0.30.2-0.10.8-0.1
Delta ambulatory time before/after self-admin0.20.21.00.4-0.0-0.30.7-0.50.3-0.01.0-0.2
Time in closed arm before self-admin0.00.10.40.00.1-0.00.10.30.1-0.1-0.6-0.1
Time in closed arm after self-admin0.40.42.81.70.2-0.20.40.50.1-0.3-0.4-0.1
Time in open arm before self-admin0.30.40.70.50.60.70.1-0.80.50.50.80.7
Time in open arm after self-admin0.80.91.6-1.30.61.00.1-1.20.81.11.00.9
Sum of active levers in priming session hrs 5-61.01.02.0-0.30.50.90.8-1.40.81.31.40.9
Time to tail flick, vehicle, before self-admin1.61.73.1-1.7-1.4-0.8-1.61.2-1.2-0.6-1.6-0.9
Time to tail flick, vehicle, after self-admin0.10.10.40.20.70.40.5-0.10.40.10.10.4
Time to tail flick, test, before self-admin0.10.10.20.50.1-0.0-0.1-0.1-0.1-0.3-0.3-0.2
Time to tail flick, test, after self-admin0.30.31.0-1.0-0.4-0.2-0.60.6-0.30.10.4-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.50.70.3-0.30.30.1-0.0-0.50.2-0.2
Delta time to tail flick, test, before/after SA0.60.63.0-1.7-0.6-0.2-1.00.6-0.40.10.3-0.4
Ambulatory time before self-admin0.91.03.1-0.6-0.9-0.5-1.30.7-1.1-0.8-1.8-0.6
Ambulatory time after self-admin0.70.81.80.2-1.3-1.1-0.30.8-0.9-0.7-0.9-1.0
Total heroin consumption1.92.35.8-1.90.61.40.4-1.41.32.41.81.3
Area under the delay curve0.20.31.5-1.2-0.50.0-0.20.00.00.70.00.1
Delay disc. indifference point, 0s delay0.20.20.8-0.6-0.10.20.3-0.40.40.90.10.4
Delay disc. indifference point, 16s delay0.10.10.2-0.1-0.5-0.4-0.10.4-0.40.0-0.0-0.3
Delay disc. indifference point, 2s delay1.01.13.6-0.60.41.20.6-1.11.21.90.61.1
Delay disc. indifference point, 24s delay0.60.61.2-1.1-0.8-0.8-0.80.8-0.8-0.5-0.6-0.7
Delay disc. indifference point, 4s delay0.10.10.7-0.8-0.10.1-0.0-0.10.10.5-0.00.1
Delay disc. indifference point, 8s delay0.60.63.2-1.8-1.1-0.2-0.60.2-0.30.6-0.3-0.2
Delay discount exponential model param0.30.31.71.30.5-0.10.2-0.0-0.0-0.7-0.0-0.1
Delay discount hyperbolic model param0.20.31.31.10.4-0.20.10.1-0.2-0.9-0.1-0.2
Fecal boli incidents, locomotor time 10.30.31.6-1.30.20.2-0.8-0.2-0.10.10.20.1
Change in fecal boli incidents, locomotor task0.10.10.2-0.40.40.20.0-0.20.2-0.0-0.50.3
Time >=10cm from walls, locomotor time 13.13.14.5-1.6-1.5-1.7-2.11.8-2.0-1.7-1.9-1.6
Bouts of movement, locomotor time 10.40.51.00.91.00.80.7-0.50.80.50.20.6
Total resting periods, locomotor time 10.91.11.81.21.31.21.1-0.91.20.80.31.0
Rest time, locomotor task time 16.57.19.81.23.03.13.0-2.23.12.72.72.4
Distance moved, locomotor task time 15.45.98.9-0.3-2.4-2.6-2.72.3-3.0-2.7-2.7-2.0
Vertical activity count, locomotor time 12.52.64.0-0.2-1.8-2.0-1.71.5-1.9-1.7-1.3-1.5
Time >=10cm from walls, locomotor time 21.11.12.9-1.5-0.7-0.8-1.71.0-1.0-0.9-1.0-0.5
Bouts of movement, locomotor time 20.80.81.9-0.8-1.1-0.8-0.50.6-1.0-0.8-1.4-0.9
Total resting periods, locomotor time 21.01.12.4-0.9-1.3-0.9-0.60.7-1.1-0.9-1.5-1.0
Rest time, locomotor task time 20.70.91.80.00.61.01.3-0.81.21.30.60.8
Distance moved, locomotor task time 21.21.42.80.3-0.8-1.1-1.71.4-1.4-1.5-1.2-0.8
Vertical activity count, locomotor time 20.10.10.50.70.2-0.3-0.30.3-0.2-0.30.30.0
Weight adjusted by age0.20.20.9-0.9-0.9-0.1-0.6-0.0-0.20.40.0-0.1
Seeking ratio, delayed vs. immediate footshock0.50.62.00.30.10.51.4-1.10.80.90.40.5
Locomotion in novel chamber0.30.42.2-1.5-0.3-0.10.5-0.10.00.40.90.2
Locomotion in novel chamber post-restriction1.01.23.4-0.2-1.1-1.3-0.41.8-1.0-1.1-0.2-1.2
Progressive ratio1.72.04.1-1.30.91.60.8-1.51.62.01.21.5
Food seeking constrained by brief footshock6.47.812.3-0.62.32.92.1-3.43.03.53.22.8
Seeking ratio, punishment vs. effort0.20.21.71.30.1-0.20.50.0-0.1-0.30.0-0.2
Run reversals in cocaine runway, females0.80.84.0-2.0-0.6-0.4-1.10.6-0.7-0.5-0.3-0.7
Run reversals in cocaine runway, males0.40.30.9-0.0-0.8-0.70.00.9-0.7-0.3-0.3-0.7
Latency to leave start box in cocaine runway3.33.65.0-1.5-1.9-1.9-2.21.7-2.1-1.8-1.8-1.9
Latency to leave start box in cocaine runway, F2.83.14.2-0.5-1.7-2.0-1.41.6-2.1-2.0-2.0-1.9
Latency to leave start box in cocaine runway, M0.90.95.1-2.2-0.10.2-1.60.0-0.20.3-0.00.1
Cd content in liver1.01.14.22.11.10.51.7-0.60.90.20.00.6
Co content in liver2.83.34.61.32.11.92.0-2.12.11.61.01.9
Cu content in liver0.60.71.60.90.50.70.9-0.50.91.11.30.6
Fe content in liver0.30.41.61.30.4-0.10.60.20.50.01.1-0.0
K content in liver1.71.73.7-1.6-1.9-1.4-1.51.4-1.2-0.2-0.0-1.3
Mg content in liver1.31.43.2-0.5-1.8-1.4-0.91.4-1.2-0.6-0.8-1.4
Mn content in liver0.10.10.40.10.10.2-0.5-0.2-0.10.1-0.60.3
Na content in liver1.51.62.8-1.0-1.4-1.4-1.71.3-1.3-1.0-0.2-1.3
Rb content in liver0.30.41.0-0.1-0.6-0.6-1.00.6-0.7-0.2-0.6-0.6
Se content in liver0.40.52.81.7-0.3-0.31.00.30.30.30.5-0.2
Sr content in liver0.50.42.8-1.7-0.10.3-0.7-0.30.00.40.20.3
Zn content in liver0.20.20.6-0.2-0.8-0.5-0.40.5-0.6-0.2-0.3-0.5