Hub : Genes

Ca8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000005669 0.12 0.05 4.3e-15 0.1 0.1 0.09 0.09 5.0e-11 4.2e-11 2.0e-10 1.4e-10
2 Adipose mRNA stability ENSRNOG00000005669 0.21 0.09 8.0e-12 0.07 0.09 0.1 0.09 5.9e-08 1.9e-10 8.4e-11 4.3e-10
3 BLA gene expression ENSRNOG00000005669 0.18 0.08 3.3e-07 0.1 0.16 0.11 0.13 4.2e-06 1.2e-08 1.3e-06 1.4e-07
4 Brain gene expression ENSRNOG00000005669 0.18 0.09 2.7e-07 0.06 0.08 0.09 0.09 3.6e-06 5.3e-08 1.1e-08 2.9e-08
5 Brain mRNA stability ENSRNOG00000005669 0.13 0.06 2.0e-06 0.06 0.05 0.04 0.05 2.0e-06 4.1e-05 5.3e-05 3.6e-05
6 Eye gene expression ENSRNOG00000005669 0.65 0.16 2.6e-03 -0 0.01 0 -0 3.4e-01 2.3e-01 3.3e-01 3.9e-01
7 LHb gene expression ENSRNOG00000005669 0.57 0.12 8.6e-11 0.18 0.26 0.23 0.2 5.4e-05 5.2e-07 3.5e-06 1.6e-05
8 Liver gene expression ENSRNOG00000005669 0.05 0.03 2.1e-03 0.03 0.01 0 0.02 4.6e-04 1.8e-02 8.4e-02 6.1e-03
9 Liver intron excision ratio chr5:21334289:21348043 0.03 0.02 5.6e-03 0.02 0 0 0.01 2.4e-03 8.4e-02 9.8e-02 1.6e-02
10 Liver intron excision ratio chr5:21350416:21354203 0.04 0.02 7.5e-03 0.01 0.01 0.01 0.01 7.4e-03 7.1e-02 5.5e-02 6.0e-02
11 Liver intron excision ratio chr5:21354298:21390247 0.12 0.05 1.1e-13 0.09 0.08 0.09 0.09 1.2e-09 1.8e-09 1.8e-10 1.7e-10
12 Liver mRNA stability ENSRNOG00000005669 0.03 0.02 2.5e-03 0 0 -0 -0 1.6e-01 1.6e-01 8.7e-01 4.0e-01
13 NAcc gene expression ENSRNOG00000005669 0.38 0.1 0.0e+00 0.42 0.4 0.42 0.41 4.2e-33 2.3e-31 1.2e-33 5.6e-33
14 OFC gene expression ENSRNOG00000005669 0.81 0.08 9.4e-16 0.55 0.51 0.53 0.52 1.3e-15 4.9e-14 6.5e-15 2.2e-14
15 PL gene expression ENSRNOG00000005669 0.55 0.19 0.0e+00 0.22 0.24 0.26 0.25 2.7e-16 5.5e-18 2.2e-19 4.7e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.82.76.21.7-1.72.50.0-1.0-0.1-1.5-0.8-1.7-0.72.0-1.62.32.02.2
BMI without tail1.02.04.82.2-1.51.5-0.50.4-0.6-1.90.7-2.00.61.4-1.61.91.41.4
Body weight1.04.110.80.5-0.2-1.8-2.02.9-2.90.41.7-0.03.3-2.61.3-1.0-2.7-2.6
Epididymis fat weight1.12.67.42.7-0.90.9-2.10.1-0.3-2.61.3-1.30.21.4-2.12.21.41.4
Glucose0.10.21.10.1-0.10.70.8-0.2-0.6-0.11.00.0-0.50.10.1-0.10.10.1
Heart weight2.63.78.2-1.3-0.5-2.1-0.80.3-2.62.20.42.60.5-2.92.2-1.9-2.9-2.3
Left kidney weight1.13.16.9-0.30.7-1.50.11.6-2.60.82.51.11.9-2.41.7-1.6-2.4-2.5
Right kidney weight0.51.43.4-0.80.3-0.50.80.3-1.91.11.41.30.4-1.51.6-1.2-1.4-1.4
Tail length2.36.914.2-0.81.0-3.3-1.43.4-2.51.42.61.03.5-3.42.2-2.6-3.5-3.8
Length with tail3.513.027.6-1.61.1-4.3-2.14.2-3.62.52.31.94.3-5.13.5-3.5-5.1-5.3
Length without tail2.65.712.3-1.90.8-2.3-1.01.9-2.32.50.32.02.1-3.53.1-2.5-3.5-3.4
Liver weight, left0.60.95.31.1-1.1-0.8-2.31.0-1.2-0.50.5-0.21.2-0.6-0.30.6-0.7-0.4
Liver weight, right0.60.92.2-1.30.2-0.70.4-0.1-0.51.5-0.51.30.2-1.21.5-1.0-1.2-1.0
Parametrial fat weight0.51.02.21.3-1.11.3-0.91.0-0.5-1.0-0.1-1.50.80.9-0.71.40.90.7
Retroperitoneal fat weight0.31.04.10.6-0.4-0.3-1.61.8-1.2-0.10.3-0.72.0-0.80.40.1-0.8-0.9
Intraocular pressure0.71.02.71.30.2-1.0-1.61.5-0.5-1.21.5-0.71.6-0.4-0.70.3-0.4-0.3
Extensor digitorum longus weight1.87.214.9-3.31.1-2.11.40.6-1.93.60.13.30.6-3.63.9-3.2-3.6-3.0
Soleus weight4.011.722.8-3.22.3-3.70.33.1-2.03.41.82.73.3-4.64.1-4.3-4.6-4.8
Tibialis anterior weight0.41.43.3-0.1-0.2-1.6-1.20.3-1.70.71.11.50.6-1.80.9-0.8-1.8-1.3
Tibia length0.72.16.92.3-1.90.3-2.61.6-1.7-1.50.5-1.31.30.2-1.11.70.2-0.1
Number of licking bursts0.40.42.5-0.90.90.01.6-0.50.30.50.10.6-0.6-0.20.6-0.7-0.2-0.0
Food consumed during 24 hour testing period0.40.53.3-0.3-0.21.31.8-0.8-0.40.3-0.00.1-0.70.20.50.20.20.7
Times rat made contact with spout0.60.72.80.4-1.7-0.3-1.20.1-1.50.4-1.10.50.1-0.80.30.4-0.80.0
Mean time between licks in bursts0.81.13.3-1.50.6-1.10.6-0.60.01.5-0.21.8-0.5-1.01.3-1.2-1.0-0.8
Mean num. licks in bursts0.81.05.41.2-2.00.0-2.30.4-1.2-0.4-0.6-0.40.6-0.1-0.51.1-0.10.2
Std. dev. time between licks in bursts0.50.62.2-1.20.10.50.5-0.9-0.11.1-1.01.5-0.80.01.1-0.10.00.2
Water consumed over 24 hours0.10.10.4-0.3-0.3-0.00.30.1-0.60.5-0.00.30.1-0.60.5-0.3-0.6-0.0
Indifference point 0 sec3.25.114.1-3.40.3-1.51.1-0.4-1.23.7-1.73.2-0.6-2.43.4-2.5-2.4-2.0
Indifference point AUC2.22.66.11.41.5-0.7-1.22.51.4-2.22.0-2.42.40.7-1.60.20.7-0.2
Indifference point function ln k1.01.45.5-0.2-1.50.90.7-2.3-0.20.7-2.00.8-2.40.4-0.00.70.40.9
Indifference point function log k1.01.45.5-0.2-1.50.90.7-2.3-0.20.7-2.00.8-2.40.4-0.00.70.40.9
Delay discounting total patch changes 0 sec3.35.314.6-3.40.3-1.51.0-0.2-1.33.8-1.83.2-0.3-2.53.5-2.5-2.4-2.1
Delay discounting total patch changes 12 sec1.01.32.9-0.80.7-1.7-1.01.6-0.50.90.40.61.5-1.31.1-1.3-1.4-1.5
Delay discounting total patch changes 18 sec0.40.61.4-0.90.1-0.60.30.7-0.61.1-0.00.60.6-0.81.2-0.9-0.8-0.9
Delay discounting total patch changes 24 sec2.43.17.6-2.70.6-1.31.21.0-0.52.8-1.31.50.8-1.82.5-2.2-1.8-1.9
Delay discounting total patch changes 6 sec1.21.84.6-2.11.8-0.81.60.70.21.60.21.00.5-1.21.8-2.0-1.2-1.4
Delay discounting time to switch 0 sec0.50.82.00.2-1.40.9-0.2-1.1-0.90.3-1.30.8-1.20.40.21.00.51.0
Delay discounting water rate 0 sec0.20.30.7-0.60.3-0.30.40.6-0.50.70.20.30.5-0.70.8-0.7-0.7-0.8
Delay discounting water rate 12 sec3.65.413.3-3.40.8-1.71.8-0.4-0.93.7-1.12.7-0.3-2.73.2-3.0-2.7-2.5
Delay discounting water rate 18 sec5.87.716.8-4.01.8-1.42.30.2-1.44.0-0.13.20.1-3.24.1-3.7-3.1-3.1
Delay discounting water rate 24 sec2.13.07.9-2.2-0.6-0.10.8-0.9-2.02.8-1.02.5-1.0-1.92.7-1.3-1.9-1.2
Delay discounting water rate 6 sec0.81.13.0-1.70.3-0.41.4-1.10.21.7-0.81.3-1.0-0.81.2-1.2-0.8-0.6
Locomotor activity3.35.310.8-2.31.0-1.2-0.0-0.0-2.62.71.53.2-0.0-3.13.3-2.8-3.1-2.6
Locomotor testing distance1.82.96.6-1.90.2-0.60.3-0.3-2.12.30.62.6-0.4-2.12.6-2.0-2.1-1.8
Locomotor testing rearing3.45.414.7-3.40.1-0.41.7-0.3-2.03.8-1.02.8-0.4-2.63.8-2.7-2.6-2.0
Light reinforcement 10.61.13.2-1.50.60.11.2-1.3-0.21.4-0.21.8-1.3-0.71.3-0.9-0.6-0.3
Light reinforcement 20.60.82.8-1.70.40.61.6-0.20.11.5-1.00.4-0.4-0.31.3-1.0-0.3-0.5
Reaction time number correct1.52.26.3-1.0-0.8-0.60.0-0.6-2.51.90.22.0-0.2-2.12.0-1.2-2.1-1.5
Reaction time mean minus median2.02.65.22.2-1.41.9-0.8-0.9-0.1-2.00.4-0.9-1.21.9-1.92.31.91.9
Reaction time mean minus median AUC1.21.54.02.0-1.41.2-1.4-0.1-0.7-1.60.5-0.9-0.31.1-1.41.81.11.1
Reaction time num false alarms0.10.10.4-0.1-0.1-0.5-0.70.3-0.30.20.00.40.3-0.20.2-0.4-0.2-0.6
Reaction time num false alarms AUC0.10.21.30.4-0.6-0.4-1.10.4-0.7-0.10.10.30.4-0.00.00.0-0.0-0.4
Reaction time trials correct on left1.52.26.3-1.0-0.8-0.60.0-0.6-2.51.90.22.0-0.2-2.12.0-1.2-2.1-1.5
Reaction time trials on left1.52.16.7-0.9-1.0-0.5-0.1-0.7-2.61.80.22.0-0.3-2.01.9-1.1-2.0-1.3
Reaction time mean2.43.37.82.8-1.61.0-1.6-1.1-0.0-2.50.7-0.6-1.51.9-2.52.61.92.4
Reaction time mean AUC2.63.47.12.7-1.81.2-1.5-1.5-0.1-2.30.4-0.4-1.91.9-2.42.61.92.6
Median of all reaction times2.12.96.62.6-1.30.7-1.6-1.00.2-2.30.6-0.6-1.41.7-2.42.31.72.3
Reaction time omissions2.12.88.02.8-2.01.2-2.4-0.4-1.4-2.11.0-0.7-0.61.1-1.72.41.11.6
Reaction time false alarm rate0.40.51.30.80.1-0.4-1.10.80.8-1.0-0.1-0.80.60.9-1.00.50.90.1
Reaction time premature initiation rate2.02.69.3-0.9-0.22.53.0-1.61.60.4-2.1-1.0-1.71.8-0.20.51.81.6
Reaction time premature initiations1.01.46.1-0.8-0.72.22.5-1.50.20.7-1.5-0.4-1.40.90.30.20.90.9
Std. dev. reaction times3.04.210.63.3-2.01.7-1.7-0.7-0.5-2.80.7-1.2-1.12.1-2.63.02.12.3
Reaction time trials completed1.52.16.7-0.9-1.0-0.5-0.1-0.7-2.61.80.22.0-0.3-2.01.9-1.1-2.0-1.3
Reaction time trials AUC1.31.96.1-0.8-0.9-0.5-0.1-0.8-2.51.70.31.9-0.4-1.91.8-1.1-1.9-1.3
Social response proportion1.31.43.2-0.7-0.8-0.9-1.1-0.1-1.81.5-0.51.7-0.2-1.81.5-0.6-1.8-0.9
Social responses1.62.04.4-0.60.9-1.2-0.31.4-1.70.81.81.21.2-2.11.5-1.4-2.1-1.8
Social time0.60.82.4-0.61.5-1.30.30.80.50.11.10.20.5-1.10.3-1.3-1.1-1.1
Conditioned locomotion0.20.30.90.60.20.5-0.2-0.40.1-0.81.0-0.3-0.20.6-0.50.60.60.4
Cocaine response after cond. corrected1.21.33.10.50.70.60.4-1.61.8-1.20.4-0.4-1.51.4-1.40.71.41.5
Cocaine response after cond. not corrected1.81.97.80.51.60.40.9-1.02.8-1.60.7-1.3-1.11.7-1.90.41.71.3
Cocaine response before conditioning0.81.02.90.21.4-0.60.61.71.4-0.80.9-1.71.30.4-0.8-0.60.3-0.6
Saline control response0.81.05.60.5-2.41.2-0.6-0.4-2.20.5-0.70.4-0.5-0.20.60.8-0.20.5
Condit. Reinf. active minus inactive responses0.50.62.70.4-0.50.8-0.10.80.6-0.4-1.0-1.70.80.9-0.60.60.80.4
Condit. Reinf. active-inactive response ratio0.50.51.8-0.30.60.20.51.01.3-0.1-0.9-1.31.00.6-0.3-0.10.60.2
Condit. Reinf. active responses0.40.51.50.8-0.90.8-0.90.7-0.2-0.6-0.4-1.20.60.6-0.50.90.60.4
Condit. Reinf. inactive responses0.40.51.31.1-0.80.6-0.80.2-1.0-0.81.0-0.60.20.2-0.50.80.20.2
Condit. Reinf. lever presses0.30.41.90.50.1-0.10.11.00.3-0.60.5-1.41.10.0-0.50.10.0-0.2
Condit. Reinf. lever reinforcers received0.40.62.10.7-0.71.1-0.40.60.1-0.6-0.4-1.40.50.8-0.60.90.80.5
Pavlov. Cond. lever latency0.50.72.6-1.30.3-0.10.1-0.8-0.31.3-0.71.6-0.6-0.51.3-0.8-0.5-0.3
Pavlov. Cond. magazine entry latency0.70.83.1-0.51.8-0.41.41.21.2-0.20.7-0.81.0-0.00.0-0.8-0.0-0.5
Pavlov. Cond. change in total contacts0.30.40.80.30.9-0.80.30.90.8-0.60.8-0.80.8-0.2-0.5-0.2-0.2-0.4
Pavlov. Cond. index score0.40.51.80.30.8-0.50.61.30.6-0.60.9-1.11.1-0.1-0.4-0.2-0.1-0.4
Pavlov. Cond. latency score0.30.41.3-0.01.1-0.41.10.61.1-0.40.6-0.80.50.1-0.4-0.40.1-0.1
Pavlov. Cond. lever contacts0.40.52.40.80.1-0.20.21.30.3-0.90.7-1.61.20.0-0.80.20.0-0.1
Pavlov. Cond. magazine entry number0.20.31.4-0.3-0.50.2-0.3-1.2-0.30.5-0.60.9-1.00.10.20.00.10.3
Pavlov. Cond. intertrial magazine entries1.01.34.11.8-2.00.4-2.0-0.1-0.9-1.1-0.1-0.9-0.00.7-1.21.40.70.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.90.40.6-0.30.61.40.6-0.70.8-1.41.2-0.0-0.5-0.1-0.0-0.3
Pavlov. Cond. response bias0.81.15.40.70.4-0.7-0.22.3-0.0-0.71.1-1.62.2-0.5-0.4-0.2-0.5-0.9
Conditioned reinforcement - actives1.01.06.0-1.21.90.72.4-0.41.40.20.6-0.1-0.20.20.4-1.00.2-0.1
Conditioned reinforcement - inactives0.91.12.70.50.51.10.8-0.51.6-1.20.3-1.2-0.41.5-1.20.61.51.1
Conditioned locomotion1.31.58.40.21.8-0.20.7-0.02.9-1.50.7-1.40.11.3-1.6-0.11.30.5
Intermittent access intake day 1-15 change1.31.23.0-1.50.6-0.21.60.0-0.81.50.11.20.2-1.21.7-1.4-1.2-1.1
Intermittent access intake escalation1.11.12.7-1.20.2-0.11.2-0.4-1.31.40.21.5-0.2-1.11.6-1.1-1.1-0.9
Intermittent access intake escalation 20.70.72.2-0.60.8-0.11.50.3-0.90.60.90.70.5-1.01.0-1.0-1.0-1.0
Intermitt. access day 1 inactive lever presses0.40.41.5-1.0-0.70.70.3-0.8-0.31.2-0.70.6-0.6-0.01.0-0.30.00.1
Intermitt. access day 15 inactive lever presses0.30.41.2-0.6-0.20.30.7-0.9-0.50.70.11.1-0.9-0.20.7-0.3-0.1-0.1
Intermitt. access escalation Index0.90.83.60.5-0.6-1.6-1.91.3-0.0-0.1-0.5-0.71.3-0.5-0.40.1-0.6-0.6
Intermittent access day 1 total infusions0.80.94.7-0.72.2-0.61.20.31.8-0.41.0-0.30.3-0.0-0.3-1.1-0.0-0.4
Intermittent access day 15 total infusions1.01.24.3-1.61.8-0.32.1-0.40.90.70.70.9-0.4-0.60.9-1.5-0.6-0.7
Intermittent access terminal intake (last 3 days)1.01.15.4-0.82.3-0.22.2-0.11.3-0.31.50.10.0-0.20.0-1.2-0.2-0.4
Intermittent access total infusions0.91.04.6-1.12.0-0.12.1-0.61.70.00.80.3-0.50.10.0-1.10.1-0.2
Intermittent access day 1 locomotion1.11.26.8-0.91.50.21.9-0.92.6-0.30.1-0.4-0.70.9-0.6-0.40.90.6
Intermittent access day 15 total locomotion1.31.45.6-2.11.00.72.4-1.30.91.4-0.41.1-1.10.01.2-1.20.1-0.1
Intermittent access total locomotion0.91.04.3-1.00.70.92.1-1.61.50.2-0.00.4-1.40.9-0.1-0.30.90.7
Intermittent access standard deviation0.70.82.50.71.40.00.30.70.9-1.41.6-1.10.70.5-1.0-0.20.5-0.1
Cocaine induced anxiety1.82.04.6-0.7-2.02.21.5-1.9-1.31.3-1.91.0-1.90.61.00.80.61.1
Post-drug Anxiety0.30.41.2-0.6-0.10.50.9-1.10.00.6-0.50.8-1.10.10.4-0.00.20.3
Baseline Anxiety1.11.13.50.51.9-1.7-1.10.91.2-1.11.8-0.30.9-0.4-0.8-0.6-0.4-0.7
Lifetime Intake0.91.04.5-1.12.1-0.22.0-0.51.9-0.10.80.2-0.40.1-0.1-1.10.1-0.2
Incentive Sensitization - Responses0.30.31.7-0.70.90.01.1-0.21.30.1-0.6-0.2-0.20.4-0.1-0.30.40.2
Incentive Sensitization - Breakpoint0.30.31.3-0.60.8-0.00.9-0.11.10.1-0.5-0.2-0.10.4-0.1-0.30.40.2
Progressive ratio test 1 active lever presses0.60.62.2-0.51.10.91.5-0.81.4-0.40.6-0.3-0.60.7-0.3-0.20.70.6
Progressive ratio test 1 breakpoint0.80.83.1-0.51.80.51.7-0.41.7-0.61.2-0.5-0.10.5-0.4-0.50.50.3
Progressive ratio test 1 inactive lever presses0.40.51.6-1.30.30.81.3-0.60.21.0-0.20.4-0.5-0.01.0-0.70.0-0.1
Progressive ratio test 2 active lever presses1.01.04.8-1.21.40.82.2-1.01.70.3-0.20.1-0.90.70.1-0.60.70.5
Progressive ratio test 2 breakpoint1.01.15.5-1.41.60.82.3-0.81.90.3-0.3-0.0-0.60.60.2-0.70.60.4
Progressive ratio test 2 inactive lever presses0.80.94.8-1.31.6-0.12.2-0.61.00.50.40.6-0.5-0.20.5-1.2-0.1-0.3
Total sessions with >9 infusions1.11.23.8-1.00.11.31.9-1.81.30.4-0.70.4-1.81.00.00.21.01.1
Short access day 1 total inactive lever presses0.60.71.9-1.2-0.30.50.9-1.40.71.0-1.10.8-1.30.30.5-0.20.30.5
Short access day 10 total inactive lever presses1.21.32.5-1.00.3-1.0-0.60.7-1.11.40.31.20.7-1.61.6-1.4-1.6-1.4
Short access day 1 total infusions0.70.83.4-0.70.90.41.6-1.01.9-0.0-0.3-0.1-0.90.8-0.4-0.20.80.7
Short access day 10 total infusions1.01.13.10.51.60.70.8-0.51.8-1.51.4-0.9-0.41.1-1.30.21.10.7
Short access total infusions0.80.93.5-0.81.90.01.9-0.51.8-0.30.7-0.1-0.40.4-0.3-0.70.40.1
Short access day 1 locomotion1.01.03.2-0.8-0.61.41.4-1.80.50.7-1.10.5-1.60.90.30.40.91.0
Short access day 10 total locomotion0.20.31.3-0.60.20.51.1-0.70.70.3-0.10.1-0.50.40.1-0.20.40.2
Short access total locomotion0.80.83.1-0.70.60.81.6-1.11.8-0.0-0.3-0.3-0.81.0-0.3-0.01.00.7
Compulsive drug intake0.80.84.0-0.4-1.70.1-1.60.3-0.41.1-2.00.00.00.00.50.40.00.2
One hour access (0.3 mA shock)1.41.67.8-0.92.8-0.41.70.82.3-0.51.3-0.91.00.1-0.2-1.30.1-0.7
One hour access (shock baseline)1.82.06.30.72.50.21.30.22.3-2.12.2-1.50.41.0-1.6-0.11.00.2
Number of responses in last shaping day0.60.62.2-0.90.50.41.5-1.4-0.10.70.51.2-1.0-0.20.8-0.6-0.2-0.0
Context. condit. distance diff. score3.34.08.81.9-1.42.30.2-2.40.6-1.9-0.1-0.5-2.62.4-2.22.62.53.0
Locomotion velocity, session 13.43.67.71.3-0.92.50.5-1.81.5-1.5-1.4-1.6-1.72.6-1.92.32.62.8
Locomotion distance, session 10.91.24.6-0.7-0.6-0.4-0.3-2.1-0.11.0-1.32.1-2.1-0.30.60.0-0.20.5
Locomotion velocity, session 21.92.24.70.30.51.30.9-2.12.2-1.0-0.7-0.7-2.02.0-1.41.02.02.0
Locomotion distance, session 20.91.24.1-1.4-0.0-1.0-0.0-1.30.31.5-1.72.0-1.4-0.61.0-0.7-0.6-0.0
Locomotion velocity, session 32.22.610.5-0.1-1.31.60.3-3.00.20.4-2.01.6-3.21.3-0.11.21.31.8
Locomotion distance, session 31.61.86.0-0.6-0.91.20.6-2.30.40.8-2.31.3-2.41.00.20.71.01.3
Stereotopy head waving bouts, day 31.41.74.0-0.70.2-0.5-1.01.6-2.01.01.01.01.6-1.41.9-0.8-1.4-1.7
Stereotopy head waving duration, day 30.91.12.7-0.5-0.2-0.8-1.11.0-1.61.00.21.10.9-1.41.4-0.7-1.4-1.4
Locomotion velocity, session 72.32.65.61.2-0.31.60.3-1.31.6-1.5-0.9-1.0-1.72.3-1.91.82.32.4
Locomotion distance, session 70.81.12.9-0.0-0.40.91.0-1.31.0-0.1-1.70.0-1.41.2-0.50.91.31.6
Stereotopy head waving bouts, day 70.80.91.7-0.0-0.5-1.2-1.31.1-1.20.50.50.70.7-1.30.6-0.6-1.3-1.3
Stereotopy head waving duration, day 70.50.63.70.7-1.5-0.3-1.90.3-1.2-0.0-0.30.5-0.0-0.4-0.10.5-0.4-0.1
Locomotion velocity, session 80.70.92.00.6-1.30.80.1-1.40.1-0.2-1.30.1-1.40.7-0.71.10.71.3
Locomotion distance, session 82.13.19.31.3-1.61.2-0.7-2.80.4-1.1-0.90.9-3.01.8-1.52.11.82.6
Degree of sensitization distance0.70.72.41.00.4-0.20.11.20.5-1.20.7-1.61.30.4-1.00.40.40.2
Degree of sensitization stereotypy0.20.31.10.3-0.8-1.1-0.8-0.0-0.20.1-0.40.3-0.3-0.6-0.4-0.2-0.6-0.3
Condit. Reinf. active minus inactive responses0.20.20.7-0.0-0.50.10.1-0.60.50.1-0.90.2-0.60.4-0.40.20.40.8
Condit. Reinf. active-inactive response ratio0.30.31.0-0.7-0.1-0.20.6-0.80.50.7-1.00.6-0.8-0.10.2-0.4-0.10.4
Condit. Reinf. active responses0.50.61.31.0-0.90.2-1.1-0.10.2-0.8-0.4-0.4-0.10.8-1.01.10.81.2
Condit. Reinf. inactive responses1.21.44.01.9-1.10.4-2.00.9-0.6-1.50.5-1.10.90.7-1.21.70.70.7
Incentive salience index mean0.20.30.80.2-0.00.2-0.2-0.10.9-0.4-0.6-0.2-0.10.8-0.60.40.80.9
Condit. Reinf. lever presses0.50.71.31.0-0.10.3-0.90.80.7-1.10.1-1.10.60.9-1.10.90.90.7
Time in familiar zone, hab. session 11.71.65.30.6-0.61.60.4-2.30.7-0.7-0.7-0.0-2.11.4-1.01.31.41.9
Time in novel zone, hab. session 10.40.40.7-0.4-0.4-0.8-0.40.6-0.80.8-0.20.70.4-0.80.8-0.6-0.8-0.8
Total zone transitions, hab. session 11.11.55.0-1.5-0.2-1.1-0.6-1.1-0.11.8-2.22.2-0.9-0.91.3-0.7-0.9-0.5
Total locomotion distance, hab. session 10.50.71.9-1.41.1-0.8-0.10.10.61.1-0.91.00.3-0.51.1-0.8-0.5-0.5
Locomotion velocity, hab. session 10.50.81.6-1.31.3-1.0-0.00.80.51.0-0.60.70.8-0.71.1-0.9-0.7-0.8
Time in familiar zone, hab. session 20.20.20.80.6-0.20.90.10.1-0.4-0.60.8-0.6-0.30.4-0.30.60.40.2
Time in novel zone, hab. session 20.30.32.1-0.40.3-1.4-0.4-0.10.70.3-0.50.70.0-0.4-0.0-0.6-0.4-0.2
Total zone transitions, hab. session 20.91.13.0-0.0-0.7-1.0-1.6-1.70.70.3-1.71.5-1.70.1-0.40.40.20.7
Total locomotion distance, hab. session 20.50.72.7-0.41.0-1.6-1.6-0.21.50.1-0.60.8-0.3-0.1-0.2-0.3-0.10.1
Locomotion velocity, hab. session 20.40.62.7-0.30.9-1.5-1.6-0.11.40.0-0.70.5-0.2-0.0-0.3-0.2-0.00.1
Novel to familiar place preference ratio2.32.47.41.50.2-1.8-2.52.70.1-1.41.3-1.82.7-0.6-1.2-0.0-0.6-1.0
Novelty place preference2.72.88.11.70.3-1.8-2.42.90.2-1.71.6-2.02.8-0.5-1.40.0-0.5-1.0
Time in novel zone, NPP test2.52.67.51.70.2-1.7-2.32.70.2-1.71.6-2.02.7-0.4-1.50.1-0.5-0.8
Total zone transitions, NPP test0.81.13.5-0.6-1.3-0.4-1.0-1.3-0.81.2-1.91.9-1.2-0.50.80.1-0.50.2
Total locomotion distance, NPP test0.20.21.0-0.70.3-0.4-0.50.10.30.7-1.00.60.1-0.10.6-0.1-0.10.1
Locomotion velocity, NPP test0.10.21.2-0.60.3-0.3-0.6-0.10.40.6-1.10.5-0.00.00.5-0.00.00.2
Pavlov. Cond. lever latency0.30.41.6-0.81.1-0.01.2-0.30.20.40.70.3-0.1-0.20.6-0.7-0.2-0.4
Pavlov. Cond. magazine entry latency1.01.32.7-0.80.2-1.5-0.41.2-0.81.10.40.81.0-1.61.1-1.4-1.6-1.5
Pavlov. Cond. change in total contacts1.01.02.1-0.5-0.5-1.3-0.91.1-1.21.0-0.30.90.9-1.51.1-0.8-1.5-1.1
Pavlov. Cond. index score0.70.92.0-0.3-0.4-1.3-1.21.2-1.10.70.20.70.9-1.40.7-0.8-1.4-1.1
Pavlov. Cond. latency score0.70.92.0-0.0-0.5-1.2-1.41.1-1.10.50.20.70.9-1.30.6-0.5-1.3-1.0
Pavlov. Cond. lever contacts0.20.21.40.5-0.9-0.3-1.20.1-0.5-0.1-0.40.2-0.1-0.2-0.20.4-0.20.1
Pavlov. Cond. magazine entry number1.82.24.71.3-0.11.60.2-1.41.3-1.7-0.3-1.1-1.22.2-1.81.82.22.0
Pavlov. Cond. intertrial magazine entries1.92.34.71.3-1.71.8-0.9-1.40.2-1.0-1.6-0.2-1.51.9-1.22.21.92.2
Pavlov. Cond. lever-magazine prob. diff.0.60.71.6-0.4-0.4-1.2-1.10.9-0.90.8-0.10.80.6-1.20.7-0.7-1.2-1.0
Pavlov. Cond. response bias0.40.51.1-0.4-0.2-1.0-0.40.8-0.60.70.00.40.5-1.10.6-0.8-1.1-0.9
Bone: apparent density0.20.31.30.4-1.11.00.10.1-0.80.0-0.8-0.50.20.20.10.80.20.4
Bone surface0.20.30.6-0.5-0.20.00.30.6-0.60.6-0.40.10.8-0.50.8-0.3-0.5-0.7
Bone volume0.10.20.4-0.3-0.20.20.40.3-0.70.5-0.20.10.5-0.50.6-0.1-0.5-0.4
Bone: connectivity density0.30.52.60.1-1.30.90.0-0.6-0.40.3-1.6-0.1-0.40.40.00.90.40.7
Bone: cortical apparent density1.11.44.20.51.01.00.90.42.0-1.3-0.1-2.00.41.6-1.30.71.60.9
Bone: cortical area0.40.61.2-0.80.3-0.40.7-0.0-0.80.90.51.10.0-0.91.1-0.9-0.9-0.9
Bone: cortical porosity0.20.21.60.6-0.1-0.30.20.5-0.3-0.61.3-0.40.4-0.1-0.5-0.1-0.1-0.4
Bone: cortical porosity0.30.40.90.7-0.9-0.5-0.50.8-0.9-0.30.4-0.50.8-0.4-0.30.0-0.4-0.6
Bone: cortical thickness0.30.61.9-0.6-0.3-0.30.5-0.6-0.90.90.11.4-0.8-0.80.8-0.7-0.8-0.7
Bone: cortical thickness0.20.20.90.30.2-0.9-0.20.70.3-0.30.2-0.30.7-0.2-0.3-0.3-0.2-0.5
Bone: cortical tissue density1.01.34.10.51.10.90.90.52.0-1.3-0.1-2.00.51.5-1.20.61.50.8
Bone: elastic displacement1.21.46.0-0.92.00.02.0-1.32.4-0.10.5-0.4-1.20.7-0.6-0.90.70.3
Bone: elastic work0.40.61.6-0.51.3-1.20.60.10.60.21.00.30.2-0.70.1-1.2-0.7-0.9
Bone: endosteal estimation0.20.51.2-0.30.3-0.10.10.7-1.00.41.10.40.9-0.80.9-0.4-0.8-0.9
Bone: endosteal perimeter0.10.20.6-0.20.6-0.5-0.1-0.2-0.20.10.80.80.0-0.50.4-0.3-0.5-0.4
Bone: final force0.91.42.9-1.20.9-0.60.81.2-1.01.20.70.81.2-1.41.7-1.3-1.4-1.5
Bone: final moment0.91.53.1-1.30.7-0.80.81.0-1.11.40.61.01.1-1.51.8-1.4-1.5-1.7
Bone: marrow area0.20.51.1-0.30.3-0.20.10.8-1.00.41.10.41.0-0.80.9-0.5-0.8-0.9
Bone: maximum diameter0.50.92.2-0.60.5-0.60.10.3-1.30.71.51.30.4-1.21.2-0.9-1.2-1.2
Bone: maximum force0.61.12.0-0.80.5-0.70.31.0-1.21.00.80.91.1-1.41.4-1.0-1.4-1.4
Bone: maximum moment0.71.22.4-0.90.2-0.90.40.8-1.31.20.61.20.9-1.51.5-1.1-1.5-1.5
Bone: minimum diameter0.30.51.3-0.50.10.51.1-0.7-1.00.60.90.9-0.5-0.50.9-0.4-0.5-0.4
Bone: periosteal estimation0.40.82.2-0.60.1-0.40.30.3-1.50.81.01.20.5-1.21.3-0.7-1.2-1.1
Bone: periosteal perimeter0.10.10.30.4-0.3-0.0-0.3-0.4-0.5-0.20.50.4-0.2-0.1-0.10.4-0.10.1
Bone: post-yield work1.21.73.5-1.0-0.5-0.9-0.30.9-1.91.50.01.80.7-1.81.9-0.9-1.8-1.4
Bone: stiffness0.81.22.5-0.20.2-0.9-0.31.5-1.60.51.50.61.5-1.41.2-0.8-1.4-1.4
Bone: tissue strength0.20.20.50.2-0.70.4-0.2-0.7-0.40.0-0.40.4-0.70.2-0.00.40.30.4
Bone: trabecular number0.20.21.0-0.0-0.50.10.10.9-0.30.3-0.7-0.71.0-0.20.30.1-0.2-0.2
Bone: trabecular spacing0.20.31.00.50.0-0.1-0.9-0.7-0.2-0.51.00.6-0.80.0-0.40.30.00.3
Bone: trabecular thickness0.20.31.40.1-0.7-0.40.20.1-1.20.30.30.50.2-0.80.4-0.2-0.8-0.5
Bone: trabecular tissue density0.40.51.3-0.50.3-0.10.20.7-1.10.60.70.60.6-0.91.1-0.5-0.9-0.9
Breakpoint value in progressive ratio session0.30.31.2-0.40.00.50.6-0.6-0.80.5-0.01.1-0.7-0.30.7-0.2-0.3-0.1
Distance traveled before self-admin0.70.73.3-1.41.8-0.5-0.10.31.40.50.30.3-0.1-0.30.5-1.2-0.3-0.7
Distance traveled after self-admin0.50.52.70.11.0-0.4-0.1-0.51.7-0.80.60.1-0.90.7-1.0-0.10.70.3
Delta time in closed arm before/after self-admin0.90.94.3-0.60.7-2.1-0.00.40.20.70.21.00.5-1.30.5-1.2-1.3-1.2
Delta time in open arm before/after self-admin0.40.41.50.3-0.41.20.01.0-1.2-0.10.7-0.70.6-0.00.30.2-0.0-0.2
Diff in mean of infusions in LGA sessions0.50.62.1-1.00.2-0.11.4-1.10.40.8-0.81.1-1.2-0.00.5-0.40.00.2
Extinction: sum of active levers before priming1.91.95.7-1.9-0.5-0.50.9-0.5-1.22.4-1.12.1-0.6-1.42.1-1.3-1.4-0.9
Active lever presses in extinction session 61.61.53.9-2.00.40.00.9-0.6-0.82.0-0.61.8-0.8-1.12.0-1.5-1.1-1.0
Delta distance traveled before/after self-admin2.02.24.82.2-1.60.9-0.1-1.40.0-1.80.2-0.6-1.31.6-2.02.01.61.9
Delta ambulatory time before/after self-admin1.41.54.42.1-1.40.5-0.2-1.0-0.3-1.70.4-0.5-0.81.2-1.71.71.21.4
Time in closed arm before self-admin1.51.74.51.2-0.21.60.50.11.2-1.6-0.3-2.10.01.9-1.61.41.91.4
Time in closed arm after self-admin0.90.92.71.00.6-0.5-0.10.51.6-1.4-0.0-1.50.70.9-1.50.50.90.4
Time in open arm before self-admin2.12.38.4-1.5-0.3-1.10.2-1.5-1.52.00.12.9-1.2-1.71.9-1.3-1.7-0.9
Time in open arm after self-admin0.70.82.6-0.8-0.60.30.4-0.4-1.61.30.41.3-0.4-1.01.4-0.6-1.0-0.5
Sum of active levers in priming session hrs 5-61.71.74.80.22.2-1.5-0.22.10.3-0.72.1-0.52.0-0.9-0.1-1.2-0.9-1.5
Time to tail flick, vehicle, before self-admin3.03.08.2-1.6-2.10.1-0.2-1.8-2.02.7-1.92.9-1.9-1.12.2-0.4-1.1-0.1
Time to tail flick, vehicle, after self-admin0.80.82.41.5-0.0-0.3-1.30.40.5-1.50.8-0.90.30.6-1.50.90.60.6
Time to tail flick, test, before self-admin1.41.43.92.0-1.31.3-1.0-0.6-1.2-1.50.4-0.8-0.30.8-1.21.80.81.3
Time to tail flick, test, after self-admin1.51.63.0-1.30.4-1.31.2-0.4-0.81.50.41.7-0.1-1.71.5-1.5-1.7-1.2
Delta time to tail flick, vehicle, before/after SA3.13.09.22.21.7-0.4-0.51.51.6-3.02.3-2.51.61.0-2.50.71.00.4
Delta time to tail flick, test, before/after SA3.22.96.5-2.41.9-2.41.70.11.11.9-0.21.70.1-1.71.5-2.5-1.7-1.7
Ambulatory time before self-admin0.50.52.9-1.01.7-0.20.00.11.10.30.50.3-0.2-0.20.3-1.0-0.2-0.5
Ambulatory time after self-admin0.20.31.30.00.8-0.70.10.00.1-0.31.10.6-0.2-0.4-0.1-0.6-0.4-0.5
Total heroin consumption0.30.41.60.30.0-0.5-1.1-1.00.4-0.3-0.00.9-1.20.4-0.50.20.40.4
Area under the delay curve1.31.44.1-0.71.8-2.00.31.20.30.41.20.61.2-1.20.6-1.5-1.2-1.6
Delay disc. indifference point, 0s delay2.52.79.0-2.51.2-0.63.0-0.3-0.22.3-0.41.9-0.3-1.22.3-2.0-1.2-1.3
Delay disc. indifference point, 16s delay1.21.23.51.10.9-1.0-0.81.80.2-1.31.9-1.21.7-0.0-0.9-0.1-0.1-0.6
Delay disc. indifference point, 2s delay0.30.41.2-0.71.1-0.80.20.50.30.40.30.40.5-0.60.6-0.9-0.6-0.7
Delay disc. indifference point, 24s delay1.41.35.11.31.0-1.5-0.81.50.1-1.42.3-0.71.7-0.4-1.0-0.2-0.4-0.7
Delay disc. indifference point, 4s delay1.41.54.3-1.31.6-2.10.50.70.50.90.31.10.8-1.30.9-1.7-1.3-1.5
Delay disc. indifference point, 8s delay1.31.44.1-1.01.4-2.0-0.01.00.10.80.61.01.0-1.30.9-1.5-1.3-1.8
Delay discount exponential model param1.51.54.90.5-1.92.20.1-1.5-0.6-0.1-1.3-0.3-1.61.1-0.31.51.11.6
Delay discount hyperbolic model param1.41.44.30.7-1.92.1-0.1-1.4-0.5-0.3-1.1-0.4-1.41.1-0.51.51.11.6
Fecal boli incidents, locomotor time 10.60.62.50.8-1.60.6-1.0-1.0-1.1-0.3-0.30.4-1.00.3-0.31.00.30.6
Change in fecal boli incidents, locomotor task0.60.63.4-0.71.8-0.11.4-0.21.1-0.11.10.2-0.20.20.1-0.70.2-0.2
Time >=10cm from walls, locomotor time 10.50.62.2-0.90.2-0.00.3-1.3-0.20.9-0.01.5-1.3-0.40.7-0.5-0.4-0.0
Bouts of movement, locomotor time 10.50.62.80.5-1.71.2-0.3-0.1-1.10.1-1.0-0.5-0.00.40.00.80.40.4
Total resting periods, locomotor time 10.60.73.50.0-1.91.2-0.1-0.5-1.30.6-1.50.0-0.40.20.50.60.20.4
Rest time, locomotor task time 12.93.27.3-1.1-2.40.70.4-2.4-2.62.3-1.92.7-2.4-1.11.90.0-1.10.1
Distance moved, locomotor task time 12.42.76.20.72.5-1.6-0.62.52.5-1.71.4-2.02.50.4-1.5-0.40.4-0.6
Vertical activity count, locomotor time 12.22.35.50.92.0-0.6-0.32.32.0-1.71.5-2.32.30.8-1.4-0.10.8-0.3
Time >=10cm from walls, locomotor time 20.70.73.3-0.6-0.50.2-0.1-1.40.70.7-1.80.9-1.50.40.10.30.40.8
Bouts of movement, locomotor time 20.20.21.4-0.5-0.50.2-0.30.2-0.40.9-1.20.20.20.10.7-0.20.1-0.0
Total resting periods, locomotor time 20.40.42.0-0.5-0.90.2-0.6-0.1-0.81.0-1.40.4-0.1-0.10.8-0.1-0.1-0.0
Rest time, locomotor task time 20.91.13.7-0.1-1.30.0-0.5-1.6-1.90.80.11.7-1.5-0.80.8-0.1-0.8-0.1
Distance moved, locomotor task time 20.81.05.6-0.71.8-0.50.91.12.4-0.2-0.4-1.00.90.6-0.4-0.50.5-0.1
Vertical activity count, locomotor time 20.80.95.8-0.71.7-0.20.80.72.4-0.3-0.6-1.00.70.8-0.5-0.40.8-0.0
Weight adjusted by age0.60.72.3-1.2-0.60.91.50.1-0.31.4-1.5-0.20.1-0.01.2-0.3-0.0-0.0
Seeking ratio, delayed vs. immediate footshock0.50.52.00.9-1.10.1-1.4-0.8-1.2-0.3-0.00.8-0.8-0.1-0.20.8-0.10.1
Locomotion in novel chamber1.01.33.6-1.6-0.50.81.3-0.8-1.11.9-0.51.4-1.0-0.71.8-0.8-0.6-0.5
Locomotion in novel chamber post-restriction2.52.97.7-2.80.30.12.1-1.80.22.6-1.72.6-1.9-1.02.1-1.4-1.0-0.5
Progressive ratio0.30.41.6-0.3-0.30.1-0.2-1.3-0.40.6-0.41.2-1.1-0.10.5-0.0-0.10.2
Food seeking constrained by brief footshock1.01.25.61.9-0.1-0.6-2.4-0.5-0.3-1.71.5-0.0-0.20.4-1.50.90.40.5
Seeking ratio, punishment vs. effort0.40.51.40.90.5-0.4-0.60.90.5-1.21.1-1.00.80.2-1.00.20.2-0.0
Run reversals in cocaine runway, females1.91.94.8-2.0-0.30.52.1-1.71.21.8-2.21.3-1.80.31.0-0.60.30.6
Run reversals in cocaine runway, males0.50.52.50.2-0.20.20.5-0.3-1.60.01.50.8-0.1-0.60.5-0.1-0.6-0.5
Latency to leave start box in cocaine runway0.30.31.0-0.9-0.10.20.90.1-0.51.0-0.50.10.4-0.51.0-0.5-0.5-0.4
Latency to leave start box in cocaine runway, F0.40.42.0-0.5-0.21.11.4-0.20.40.3-1.0-0.80.00.50.20.30.60.5
Latency to leave start box in cocaine runway, M0.50.51.4-0.20.1-0.7-0.40.0-1.00.41.11.2-0.1-1.00.7-0.6-1.0-0.6
Cd content in liver3.74.011.83.4-2.00.9-2.2-0.2-0.2-3.00.7-2.30.21.6-2.92.81.61.7
Co content in liver0.91.14.0-1.2-0.70.40.4-1.7-0.11.4-2.01.3-1.6-0.10.9-0.3-0.10.3
Cu content in liver0.50.61.1-0.90.9-1.0-0.10.4-0.00.70.30.70.6-1.00.8-1.0-1.0-1.1
Fe content in liver0.60.71.60.90.10.2-0.4-0.91.0-1.10.1-0.5-0.81.1-1.30.81.11.0
K content in liver0.40.41.50.20.60.71.00.5-0.4-0.41.2-0.91.10.00.2-0.10.0-0.3
Mg content in liver0.40.42.50.30.70.41.10.5-0.3-0.51.6-0.60.9-0.00.0-0.2-0.0-0.3
Mn content in liver1.11.33.9-0.5-0.5-0.8-0.70.7-2.01.20.31.30.8-1.51.4-0.7-1.5-1.4
Na content in liver0.20.21.6-0.10.60.51.3-0.50.4-0.20.2-0.0-0.30.3-0.00.20.30.3
Rb content in liver2.73.37.4-1.7-0.6-1.0-0.90.8-2.52.5-0.62.20.9-2.52.7-1.6-2.5-2.0
Se content in liver1.21.45.70.31.5-0.50.32.0-0.1-0.72.4-1.12.1-0.60.0-0.6-0.6-1.3
Sr content in liver1.71.63.60.9-1.71.3-0.3-1.9-0.0-0.5-1.30.1-1.91.3-1.01.51.31.6
Zn content in liver0.20.20.7-0.3-0.70.80.7-0.5-0.60.6-0.80.10.1-0.00.60.1-0.00.0