Hub : Genes

Desi1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000007424 0.03 0.02 1.0e-03 0.02 0.01 0.01 0.01 1.8e-03 1.6e-02 8.2e-03 2.5e-02
2 Adipose alternative TSS ENSRNOT00000103557 0.04 0.03 2.2e-04 0.01 0.02 0.01 0.01 1.4e-02 3.9e-03 1.4e-02 8.6e-03
3 Adipose isoform ratio ENSRNOT00000007424 0.05 0.03 1.0e-04 0.03 0.02 0.01 0.02 4.3e-04 2.7e-03 1.0e-02 1.6e-03
4 Adipose isoform ratio ENSRNOT00000103557 0.05 0.03 1.0e-04 0.03 0.02 0.02 0.02 4.5e-04 2.8e-03 5.3e-03 1.5e-03
5 Adipose mRNA stability ENSRNOG00000005577 0.46 0.12 0.0e+00 0.34 0.34 0.34 0.35 1.8e-39 1.9e-39 1.2e-38 7.9e-40
6 BLA gene expression ENSRNOG00000005577 0.16 0.09 6.3e-04 0.06 0.05 0.04 0.05 5.4e-04 1.0e-03 5.2e-03 1.7e-03
7 BLA mRNA stability ENSRNOG00000005577 0.06 0.05 6.6e-03 0.05 0.03 0.02 0.03 1.4e-03 9.3e-03 3.3e-02 6.7e-03
8 Brain gene expression ENSRNOG00000005577 0.44 0.13 0.0e+00 0.28 0.29 0.29 0.3 1.4e-26 3.8e-27 1.9e-27 1.1e-27
9 Brain mRNA stability ENSRNOG00000005577 0.05 0.03 1.7e-05 0.04 0.04 0.04 0.03 1.6e-04 3.3e-04 1.0e-04 1.7e-03
10 LHb gene expression ENSRNOG00000005577 0.52 0.18 2.5e-04 0.05 0.08 0.07 0.07 2.1e-02 7.0e-03 9.8e-03 9.7e-03
11 NAcc gene expression ENSRNOG00000005577 0.06 0.04 6.8e-03 0.03 0.02 0.01 0.02 1.6e-03 8.2e-03 4.0e-02 1.0e-02
12 NAcc mRNA stability ENSRNOG00000005577 0.03 0.02 7.9e-03 0.01 0.01 0.01 0.01 6.0e-02 3.3e-02 7.6e-02 9.2e-02
13 PL gene expression ENSRNOG00000005577 0.09 0.07 8.4e-03 0.02 0.01 0 0.01 7.3e-03 4.6e-02 1.8e-01 4.2e-02
14 PL mRNA stability ENSRNOG00000005577 0.05 0.04 3.2e-03 0.01 0.03 0.02 0.01 4.0e-02 4.1e-03 1.3e-02 2.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.23.76.02.1-2.52.3-2.32.2-0.8-2.2-0.4-1.12.31.4-2.21.9-2.0
BMI without tail0.00.10.30.5-0.1-0.00.00.1-0.2-0.30.2-0.40.6-0.30.0-0.00.2
Body weight1.14.87.92.7-2.32.6-2.62.7-1.9-2.8-1.7-0.91.61.0-2.61.0-2.6
Epididymis fat weight2.35.310.52.3-1.52.8-2.83.1-2.8-2.3-3.2-1.50.5-0.4-2.90.3-2.6
Glucose0.40.51.1-0.80.4-0.90.9-0.90.80.81.10.50.4-0.10.80.21.0
Heart weight2.53.67.32.6-2.41.3-1.32.0-0.6-2.4-0.4-1.82.72.2-1.91.9-1.6
Left kidney weight9.928.444.76.7-5.65.8-5.86.3-4.8-6.5-4.4-4.03.93.0-6.32.4-6.7
Right kidney weight10.930.948.26.9-6.15.9-5.96.5-4.7-6.8-4.1-4.64.33.5-6.52.8-6.9
Tail length0.20.61.1-0.31.0-1.11.1-0.7-0.10.5-0.1-0.3-0.8-0.80.8-1.00.9
Length with tail0.31.02.51.4-0.60.9-0.91.1-1.4-1.4-1.6-0.3-0.00.2-1.0-0.5-1.3
Length without tail1.12.34.61.6-1.62.0-2.01.7-1.1-1.7-1.4-0.30.71.1-1.80.6-2.1
Liver weight, left0.81.34.91.0-0.10.9-0.91.3-1.9-1.0-2.2-0.0-0.4-0.8-1.0-1.0-1.0
Liver weight, right1.93.18.41.3-0.42.2-2.22.1-2.8-1.4-2.90.1-0.3-1.5-1.9-0.7-1.7
Parametrial fat weight0.10.30.90.2-0.60.7-0.70.30.2-0.10.2-0.60.60.6-0.60.9-0.3
Retroperitoneal fat weight2.68.515.22.9-2.73.9-3.93.8-2.7-3.0-2.9-1.41.60.6-3.81.4-3.5
Intraocular pressure0.30.41.50.3-0.20.8-0.81.0-0.7-0.1-1.2-0.7-0.5-0.2-0.7-0.2-0.7
Extensor digitorum longus weight0.10.51.1-0.20.7-1.01.0-1.10.10.40.60.40.0-0.61.0-0.61.0
Soleus weight0.10.30.9-0.0-0.1-0.90.9-0.70.70.11.0-0.40.10.90.40.50.1
Tibialis anterior weight0.51.64.1-1.00.6-1.41.4-1.62.01.21.90.1-0.00.21.40.61.5
Tibia length0.72.04.11.8-1.51.6-1.61.7-1.2-1.7-1.3-0.80.71.0-1.60.3-2.0
Number of licking bursts0.30.30.7-0.50.6-0.80.8-0.80.40.50.60.2-0.8-0.20.7-0.40.4
Food consumed during 24 hour testing period1.41.72.61.2-1.61.6-1.61.4-0.6-1.3-0.3-1.31.30.9-1.51.1-1.5
Times rat made contact with spout0.80.91.51.2-1.21.0-1.00.8-0.2-1.20.1-1.20.70.9-1.01.0-1.1
Mean time between licks in bursts0.50.71.3-1.00.8-1.11.1-0.80.91.10.7-0.1-0.5-0.60.90.01.1
Mean num. licks in bursts1.51.82.81.6-1.41.7-1.71.6-0.9-1.5-1.0-1.51.10.6-1.60.8-1.5
Std. dev. time between licks in bursts0.91.12.5-1.00.4-1.61.6-1.31.21.11.50.40.20.51.3-0.01.0
Water consumed over 24 hours0.91.12.21.4-1.11.1-1.10.9-0.8-1.5-0.6-1.30.70.8-1.00.2-1.3
Indifference point 0 sec0.40.71.7-0.4-0.0-1.01.0-0.91.00.31.30.80.71.00.80.10.7
Indifference point AUC0.10.10.5-0.10.1-0.20.2-0.40.10.10.20.3-0.70.10.1-0.4-0.3
Indifference point function ln k0.71.11.81.3-0.91.2-1.21.1-1.0-1.3-1.0-0.91.00.5-1.10.2-0.9
Indifference point function log k0.71.11.81.3-0.91.2-1.21.1-1.0-1.3-1.0-0.91.00.5-1.10.2-0.9
Delay discounting total patch changes 0 sec0.50.81.8-0.40.1-1.21.2-1.01.10.41.30.70.60.91.00.00.8
Delay discounting total patch changes 12 sec0.10.20.80.1-0.5-0.00.0-0.20.2-0.10.50.50.70.9-0.00.3-0.3
Delay discounting total patch changes 18 sec0.20.31.3-0.1-0.5-0.60.6-0.30.8-0.10.90.20.61.10.30.40.1
Delay discounting total patch changes 24 sec0.20.30.9-0.40.3-0.60.6-0.60.40.40.40.9-0.30.10.5-0.40.4
Delay discounting total patch changes 6 sec0.30.52.10.3-0.4-0.90.9-0.80.6-0.31.40.10.71.10.50.00.0
Delay discounting time to switch 0 sec0.30.41.8-1.00.5-0.00.0-0.1-0.11.1-0.21.3-0.1-0.90.3-0.20.6
Delay discounting water rate 0 sec0.40.62.10.9-0.4-0.70.7-0.60.6-1.11.1-1.10.81.50.30.20.1
Delay discounting water rate 12 sec0.20.30.70.10.5-0.80.8-0.60.2-0.20.3-0.1-0.20.20.8-0.70.6
Delay discounting water rate 18 sec0.81.02.5-0.50.9-1.61.6-1.50.60.61.00.6-0.50.31.4-1.01.0
Delay discounting water rate 24 sec0.40.62.01.1-0.7-0.10.10.00.2-1.00.3-1.41.11.3-0.10.1-0.3
Delay discounting water rate 6 sec0.60.92.5-0.51.2-1.21.2-1.1-0.10.30.10.2-1.0-0.81.2-1.60.8
Locomotor activity1.72.75.12.3-1.32.0-2.01.8-2.0-2.0-1.8-1.40.90.3-1.7-0.1-1.8
Locomotor testing distance0.00.00.10.00.20.1-0.1-0.0-0.00.2-0.1-0.2-0.2-0.30.1-0.10.1
Locomotor testing rearing1.01.63.11.5-1.01.5-1.51.8-1.4-1.4-1.4-1.20.4-0.3-1.50.4-1.4
Light reinforcement 10.30.62.30.60.3-0.40.40.4-1.5-0.4-1.01.0-0.5-0.90.0-1.3-0.5
Light reinforcement 20.40.51.20.4-0.40.9-0.91.0-1.1-0.5-1.10.40.3-0.7-0.90.1-0.7
Reaction time number correct1.21.84.8-1.31.8-1.21.2-1.0-0.01.2-0.30.8-2.2-1.81.2-1.71.1
Reaction time mean minus median0.20.20.90.70.00.2-0.20.3-0.9-0.6-0.5-0.80.1-0.4-0.2-0.3-0.1
Reaction time mean minus median AUC0.50.72.00.9-0.41.0-1.00.9-0.9-0.8-0.9-1.40.3-0.3-0.80.3-0.5
Reaction time num false alarms0.40.61.90.00.8-0.50.5-0.1-1.3-0.0-0.80.5-0.7-1.40.4-1.30.3
Reaction time num false alarms AUC0.50.61.90.00.9-0.70.7-0.3-1.30.0-0.80.3-0.8-1.30.5-1.40.3
Reaction time trials correct on left1.21.84.8-1.31.8-1.21.2-1.0-0.01.2-0.30.8-2.2-1.81.2-1.71.1
Reaction time trials on left1.31.95.2-1.31.9-1.21.2-1.1-0.01.3-0.30.8-2.3-1.81.3-1.81.1
Reaction time mean0.10.10.4-0.20.3-0.70.7-0.30.30.20.2-0.20.1-0.10.4-0.20.6
Reaction time mean AUC0.10.10.3-0.20.3-0.50.5-0.30.30.30.2-0.20.0-0.10.4-0.10.6
Median of all reaction times0.20.30.8-0.50.4-0.90.9-0.60.80.60.5-0.00.10.10.6-0.10.8
Reaction time omissions0.30.40.8-0.40.9-0.90.9-0.5-0.20.4-0.1-0.5-0.9-0.70.6-0.80.6
Reaction time false alarm rate0.10.20.80.5-0.1-0.10.10.3-0.9-0.5-0.4-0.20.5-0.3-0.2-0.1-0.2
Reaction time premature initiation rate0.30.51.70.0-0.5-0.50.5-0.70.60.11.30.71.10.90.50.20.2
Reaction time premature initiations0.30.40.9-0.40.2-0.80.8-0.90.60.51.00.80.10.20.8-0.40.5
Std. dev. reaction times0.30.41.11.0-0.30.4-0.40.8-1.0-0.8-0.8-1.00.4-0.1-0.5-0.1-0.4
Reaction time trials completed1.31.95.2-1.31.9-1.21.2-1.1-0.01.3-0.30.8-2.3-1.81.3-1.81.1
Reaction time trials AUC1.01.54.1-1.21.7-1.11.1-0.9-0.11.1-0.40.6-2.0-1.71.1-1.71.0
Social response proportion0.40.52.60.5-0.80.1-0.10.10.6-0.50.70.21.61.1-0.10.90.2
Social responses0.10.20.60.10.4-0.30.3-0.3-0.4-0.1-0.10.8-0.4-0.70.3-0.70.1
Social time1.62.13.7-1.81.1-1.61.6-1.61.71.71.91.3-0.7-0.51.60.11.7
Conditioned locomotion0.50.61.80.6-0.00.7-0.70.9-1.2-0.6-1.30.3-0.4-1.0-0.7-0.3-0.6
Cocaine response after cond. corrected0.10.10.30.20.10.4-0.40.1-0.4-0.3-0.30.2-0.3-0.6-0.1-0.3-0.1
Cocaine response after cond. not corrected0.10.10.60.20.30.2-0.2-0.1-0.7-0.3-0.20.3-0.1-0.80.1-0.50.0
Cocaine response before conditioning0.10.20.3-0.40.3-0.50.5-0.5-0.10.40.40.30.3-0.40.5-0.10.5
Saline control response0.40.52.50.80.5-0.20.2-0.1-1.6-0.7-1.0-0.7-0.1-0.90.1-1.1-0.0
Condit. Reinf. active minus inactive responses0.30.41.50.1-0.9-0.00.00.20.7-0.00.6-0.90.61.2-0.30.8-0.6
Condit. Reinf. active-inactive response ratio0.60.72.60.2-1.20.4-0.40.40.8-0.10.7-0.71.01.6-0.41.1-0.7
Condit. Reinf. active responses0.50.71.70.9-1.10.6-0.60.9-0.5-0.9-0.4-0.90.60.9-0.90.4-1.3
Condit. Reinf. inactive responses0.60.81.80.9-0.70.8-0.81.1-1.3-1.0-1.1-0.50.0-0.1-1.1-0.0-1.3
Condit. Reinf. lever presses0.20.30.9-0.4-0.1-0.60.6-0.70.80.30.90.00.50.80.50.20.3
Condit. Reinf. lever reinforcers received0.30.41.00.5-0.90.3-0.30.6-0.1-0.5-0.1-0.70.61.0-0.60.5-1.0
Pavlov. Cond. lever latency0.71.02.00.7-0.21.4-1.41.4-0.9-0.7-1.4-0.5-0.7-1.0-1.20.3-0.9
Pavlov. Cond. magazine entry latency2.83.39.0-1.80.5-2.02.0-2.33.01.72.6-0.00.51.61.90.71.9
Pavlov. Cond. change in total contacts1.31.88.2-0.1-1.1-0.80.8-1.01.80.12.1-0.01.92.90.61.10.3
Pavlov. Cond. index score1.82.45.4-1.40.3-1.81.8-2.02.31.32.30.20.71.61.70.41.5
Pavlov. Cond. latency score2.32.97.0-1.50.3-2.02.0-2.22.61.52.60.10.81.71.80.61.6
Pavlov. Cond. lever contacts0.71.02.3-0.80.1-1.21.2-1.41.10.71.50.61.01.21.20.00.9
Pavlov. Cond. magazine entry number1.62.05.91.3-0.11.5-1.51.6-2.4-1.2-2.00.3-0.6-1.8-1.3-0.7-1.2
Pavlov. Cond. intertrial magazine entries2.12.74.31.8-1.92.0-2.02.0-0.7-1.7-0.5-1.21.40.7-2.11.9-1.8
Pavlov. Cond. lever-magazine prob. diff.1.82.35.1-1.50.4-1.81.8-2.02.21.42.20.30.61.51.70.31.5
Pavlov. Cond. response bias0.91.33.2-0.9-0.1-1.21.2-1.41.60.91.80.51.01.71.10.40.9
Conditioned reinforcement - actives0.40.41.00.4-0.40.7-0.70.9-0.7-0.5-0.7-0.7-0.6-0.2-0.70.1-1.0
Conditioned reinforcement - inactives0.40.41.20.0-0.6-0.70.7-0.00.90.01.1-1.00.60.90.10.9-0.0
Conditioned locomotion1.62.03.71.4-1.71.9-1.91.8-0.8-1.3-0.5-0.50.80.8-1.61.2-1.9
Intermittent access intake day 1-15 change0.30.30.5-0.60.4-0.40.4-0.60.70.60.70.7-0.3-0.20.5-0.40.5
Intermittent access intake escalation0.40.40.6-0.60.4-0.60.6-0.70.80.60.70.7-0.2-0.30.6-0.40.6
Intermittent access intake escalation 20.20.20.3-0.40.4-0.60.6-0.50.10.30.20.5-0.2-0.20.5-0.50.4
Intermitt. access day 1 inactive lever presses1.21.34.71.1-1.4-0.00.00.50.6-1.20.9-1.21.82.2-0.61.3-0.6
Intermitt. access day 15 inactive lever presses1.92.15.31.1-1.90.4-0.40.81.1-1.11.1-2.11.92.3-1.02.2-1.0
Intermitt. access escalation Index0.20.20.70.0-0.5-0.50.50.00.7-0.10.8-0.00.40.70.10.2-0.1
Intermittent access day 1 total infusions0.91.02.31.0-1.30.7-0.71.4-0.4-1.1-0.4-1.50.80.9-1.20.9-1.2
Intermittent access day 15 total infusions0.10.20.40.1-0.5-0.10.10.30.7-0.10.6-0.50.30.7-0.20.4-0.2
Intermittent access terminal intake (last 3 days)0.00.00.20.0-0.20.2-0.20.4-0.0-0.1-0.1-0.2-0.10.1-0.30.1-0.3
Intermittent access total infusions0.30.30.60.4-0.70.4-0.40.80.1-0.4-0.1-0.70.40.6-0.70.7-0.6
Intermittent access day 1 locomotion0.40.40.80.5-0.90.6-0.60.90.0-0.60.2-0.90.70.7-0.60.8-0.6
Intermittent access day 15 total locomotion0.10.20.40.3-0.40.6-0.60.60.0-0.2-0.2-0.40.10.4-0.40.1-0.4
Intermittent access total locomotion0.50.51.00.6-1.00.8-0.80.90.2-0.50.1-0.80.70.8-0.80.9-0.7
Intermittent access standard deviation0.50.61.30.6-1.10.5-0.51.00.3-0.70.00.11.10.8-0.81.1-0.6
Cocaine induced anxiety1.11.22.70.8-1.41.2-1.20.80.6-0.70.2-0.91.61.5-1.11.6-0.7
Post-drug Anxiety0.40.41.20.8-0.90.5-0.50.40.3-0.50.1-0.31.01.1-0.50.7-0.5
Baseline Anxiety1.11.22.0-1.01.4-1.11.1-1.2-0.00.90.31.1-1.4-1.21.3-1.41.0
Lifetime Intake0.91.02.30.7-1.50.7-0.71.20.4-0.80.2-0.91.01.3-1.11.5-1.1
Incentive Sensitization - Responses0.50.51.6-0.3-0.3-0.60.6-0.41.30.31.2-0.60.40.80.21.00.2
Incentive Sensitization - Breakpoint0.50.51.5-0.1-0.6-0.30.3-0.21.20.21.2-0.60.61.0-0.01.2-0.0
Progressive ratio test 1 active lever presses0.60.61.40.4-1.10.6-0.60.90.6-0.40.3-0.80.71.0-0.91.2-0.8
Progressive ratio test 1 breakpoint0.30.30.80.1-0.70.5-0.50.70.5-0.30.2-0.60.30.6-0.80.9-0.6
Progressive ratio test 1 inactive lever presses1.41.54.60.4-1.50.1-0.10.71.4-0.41.4-1.12.01.8-0.72.2-0.3
Progressive ratio test 2 active lever presses0.40.41.5-0.2-0.6-0.00.00.11.20.20.8-0.90.30.9-0.31.2-0.3
Progressive ratio test 2 breakpoint0.50.62.10.1-0.90.2-0.20.31.2-0.11.0-1.00.71.1-0.51.4-0.4
Progressive ratio test 2 inactive lever presses1.01.24.1-0.4-0.7-0.80.8-0.32.00.51.7-1.31.01.40.21.50.4
Total sessions with >9 infusions1.51.63.51.3-1.90.9-0.91.7-0.2-1.2-0.0-0.91.11.2-1.61.5-1.7
Short access day 1 total inactive lever presses1.61.83.31.8-1.81.0-1.01.3-0.5-1.7-0.1-1.51.51.7-1.20.9-1.5
Short access day 10 total inactive lever presses0.60.61.41.2-0.80.4-0.40.9-0.8-1.1-0.7-1.00.60.8-0.70.0-0.8
Short access day 1 total infusions1.92.04.01.6-2.00.8-0.81.7-0.3-1.50.0-1.41.61.6-1.51.6-1.6
Short access day 10 total infusions0.60.71.70.4-1.11.0-1.01.00.3-0.50.2-0.20.90.6-1.11.3-0.8
Short access total infusions2.32.65.91.3-2.31.2-1.21.90.3-1.40.3-1.01.81.8-1.92.4-1.7
Short access day 1 locomotion0.30.31.20.1-0.80.0-0.00.50.5-0.20.8-0.20.90.7-0.51.1-0.3
Short access day 10 total locomotion0.20.20.6-0.5-0.2-0.20.20.20.50.50.80.10.5-0.20.10.80.4
Short access total locomotion1.01.13.20.5-1.51.0-1.01.40.2-0.60.5-0.11.20.9-1.21.8-1.0
Compulsive drug intake1.31.32.4-1.11.2-1.31.3-1.61.01.30.80.9-1.3-0.51.4-0.71.1
One hour access (0.3 mA shock)0.30.41.1-1.00.5-0.60.6-0.30.80.90.40.4-0.6-0.30.50.30.6
One hour access (shock baseline)0.10.10.3-0.5-0.10.4-0.40.50.10.2-0.20.20.0-0.2-0.40.40.0
Number of responses in last shaping day1.41.45.9-0.9-0.2-1.31.3-1.01.90.92.40.20.90.70.81.10.9
Context. condit. distance diff. score4.85.98.92.9-1.92.7-2.73.0-2.8-2.9-2.9-2.21.20.2-2.90.4-2.7
Locomotion velocity, session 10.50.62.50.40.4-0.30.30.1-1.3-0.4-1.0-0.1-1.1-0.60.0-1.6-0.7
Locomotion distance, session 11.92.54.9-1.81.9-1.91.9-1.70.41.70.51.0-2.2-1.31.7-1.61.2
Locomotion velocity, session 20.20.31.20.5-0.30.6-0.60.4-1.1-0.6-0.40.30.2-0.3-0.4-0.6-0.7
Locomotion distance, session 21.72.44.7-1.90.9-1.91.9-2.02.01.82.20.7-0.60.41.80.11.5
Locomotion velocity, session 30.50.62.00.20.40.7-0.70.4-1.4-0.2-1.30.0-0.7-1.2-0.4-1.1-0.6
Locomotion distance, session 31.31.44.9-1.41.7-1.01.0-0.90.01.3-0.20.3-2.2-1.61.0-1.40.8
Stereotopy head waving bouts, day 30.70.91.71.3-0.91.1-1.11.0-1.1-1.2-0.9-0.40.80.4-1.0-0.1-1.2
Stereotopy head waving duration, day 32.73.36.02.4-1.62.1-2.12.0-2.4-2.3-1.9-0.21.40.3-1.8-0.3-2.1
Locomotion velocity, session 70.30.30.8-0.40.20.8-0.80.4-0.60.4-0.50.3-0.7-0.9-0.4-0.3-0.3
Locomotion distance, session 70.40.51.6-1.30.10.4-0.4-0.11.01.20.80.1-0.3-0.0-0.01.00.3
Stereotopy head waving bouts, day 72.83.19.42.2-0.61.4-1.41.9-3.1-2.1-2.9-0.1-0.0-0.7-1.5-1.7-2.0
Stereotopy head waving duration, day 72.02.47.21.8-0.31.3-1.31.6-2.7-1.7-2.60.1-0.0-1.0-1.2-1.6-1.4
Locomotion velocity, session 82.22.75.52.3-1.71.8-1.81.6-1.5-2.3-1.1-1.21.31.3-1.60.2-2.0
Locomotion distance, session 80.60.92.21.2-0.60.9-0.91.1-1.5-1.1-1.2-1.00.5-0.0-1.0-0.0-1.0
Degree of sensitization distance2.52.56.01.2-2.11.9-1.91.40.3-1.20.2-0.72.41.7-1.72.4-1.1
Degree of sensitization stereotypy2.12.37.21.6-0.21.0-1.01.6-2.6-1.6-2.7-0.2-0.6-1.0-1.1-1.7-1.5
Condit. Reinf. active minus inactive responses0.20.30.8-0.8-0.1-0.40.4-0.40.70.90.90.10.30.20.30.50.2
Condit. Reinf. active-inactive response ratio0.20.20.50.4-0.50.5-0.50.5-0.5-0.3-0.4-0.50.3-0.0-0.60.1-0.7
Condit. Reinf. active responses1.21.53.1-1.60.6-1.41.4-1.41.41.71.80.50.1-0.01.20.41.3
Condit. Reinf. inactive responses2.22.74.6-2.11.4-1.91.9-1.91.72.01.90.8-0.4-0.31.90.12.2
Incentive salience index mean0.60.82.1-1.30.1-0.90.9-0.81.21.41.50.50.30.20.60.80.6
Condit. Reinf. lever presses0.91.22.8-1.70.5-1.31.3-1.01.11.61.51.2-0.1-0.21.00.41.0
Time in familiar zone, hab. session 10.20.10.90.00.1-0.10.10.4-0.40.2-0.40.2-0.9-0.5-0.3-0.3-0.5
Time in novel zone, hab. session 10.70.72.51.4-0.50.8-0.80.5-1.0-1.6-0.7-0.51.10.2-0.5-0.3-0.4
Total zone transitions, hab. session 12.63.66.1-2.12.3-2.52.5-2.20.82.00.70.9-2.4-1.32.1-1.71.7
Total locomotion distance, hab. session 11.92.77.1-1.22.2-1.71.7-1.5-0.81.2-0.40.9-2.3-2.01.6-2.71.1
Locomotion velocity, hab. session 11.92.75.1-1.52.1-2.02.0-1.7-0.31.50.11.0-2.1-1.71.8-2.31.3
Time in familiar zone, hab. session 20.70.72.7-0.61.0-0.30.30.2-1.00.4-1.00.9-1.4-1.60.1-1.10.2
Time in novel zone, hab. session 20.90.92.71.3-1.10.3-0.3-0.10.4-1.20.6-1.51.41.6-0.30.7-0.5
Total zone transitions, hab. session 20.50.72.2-0.70.4-1.51.5-1.00.60.61.00.3-0.50.41.0-0.20.4
Total locomotion distance, hab. session 20.50.61.3-0.70.6-1.21.2-1.00.50.71.00.6-0.4-0.11.0-0.40.7
Locomotion velocity, hab. session 20.91.32.9-1.10.9-1.71.7-1.40.71.11.20.8-0.7-0.31.4-0.61.1
Novel to familiar place preference ratio3.13.28.32.9-1.11.8-1.81.6-1.9-2.7-2.2-2.00.70.6-1.6-0.6-1.7
Novelty place preference3.94.110.03.2-1.22.1-2.11.9-2.2-3.0-2.5-2.20.60.5-1.8-0.7-2.0
Time in novel zone, NPP test4.85.111.93.4-1.52.3-2.32.1-2.4-3.3-2.7-2.50.80.7-2.1-0.6-2.3
Total zone transitions, NPP test1.92.85.7-1.71.9-2.42.4-1.90.71.60.80.5-2.1-1.01.9-1.51.4
Total locomotion distance, NPP test0.81.12.1-1.11.1-1.41.4-1.40.61.10.80.4-1.1-0.41.4-1.01.0
Locomotion velocity, NPP test1.72.43.6-1.81.7-1.91.9-1.80.81.91.01.0-1.6-1.11.8-1.21.5
Pavlov. Cond. lever latency1.01.22.51.6-0.71.0-1.01.3-1.1-1.6-1.6-1.20.10.1-1.1-0.3-1.2
Pavlov. Cond. magazine entry latency1.01.24.0-1.40.3-1.01.0-1.11.71.52.00.5-0.10.30.91.01.0
Pavlov. Cond. change in total contacts1.31.35.2-1.30.1-1.01.0-1.21.71.32.30.70.20.80.91.10.9
Pavlov. Cond. index score0.70.93.6-1.1-0.1-0.50.5-0.81.51.11.90.40.50.70.51.30.6
Pavlov. Cond. latency score0.60.83.1-1.0-0.1-0.50.5-0.81.41.01.80.40.50.70.51.20.6
Pavlov. Cond. lever contacts1.31.63.8-1.70.7-1.21.2-1.41.61.72.00.8-0.00.11.20.71.4
Pavlov. Cond. magazine entry number0.70.93.11.2-0.20.8-0.80.9-1.5-1.3-1.7-0.20.1-0.3-0.6-1.1-0.7
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.60.4-1.01.0-1.11.10.71.00.2-0.10.51.0-0.10.8
Pavlov. Cond. lever-magazine prob. diff.0.81.03.5-1.40.1-0.70.7-0.91.61.41.90.60.10.40.61.20.8
Pavlov. Cond. response bias1.11.44.2-1.70.3-0.90.9-1.11.71.72.00.80.10.30.81.21.0
Bone: apparent density0.20.30.7-0.60.4-0.30.3-0.70.70.60.50.8-0.10.20.7-0.20.7
Bone surface0.20.31.90.10.5-0.20.2-0.5-0.7-0.2-0.20.6-0.5-0.00.5-1.4-0.1
Bone volume0.10.10.50.10.20.1-0.1-0.2-0.5-0.1-0.20.5-0.2-0.00.2-0.7-0.0
Bone: connectivity density0.10.10.5-0.30.10.2-0.2-0.40.50.20.30.70.00.40.4-0.10.3
Bone: cortical apparent density0.40.51.2-1.10.6-0.80.8-0.80.81.10.60.3-0.7-0.10.8-0.10.7
Bone: cortical area1.11.73.01.6-1.51.4-1.41.7-1.4-1.6-1.1-0.31.00.6-1.50.3-1.7
Bone: cortical porosity0.30.30.70.5-0.40.6-0.60.5-0.9-0.4-0.60.30.7-0.3-0.50.0-0.4
Bone: cortical porosity0.90.91.81.1-0.81.3-1.31.0-1.3-1.0-0.90.21.0-0.1-1.00.0-1.0
Bone: cortical thickness0.50.92.80.3-1.30.7-0.70.70.8-0.20.8-0.61.21.4-0.71.7-0.7
Bone: cortical thickness0.80.92.80.6-1.30.4-0.40.70.7-0.60.7-1.01.01.5-0.81.7-0.8
Bone: cortical tissue density0.40.51.1-1.00.5-0.80.8-0.80.81.10.60.2-0.6-0.10.8-0.00.6
Bone: elastic displacement0.40.52.00.90.20.2-0.20.1-1.2-0.8-0.9-0.2-0.4-0.3-0.0-1.4-0.4
Bone: elastic work1.82.45.12.2-1.61.8-1.81.6-1.5-2.0-1.1-0.61.51.1-1.50.0-1.7
Bone: endosteal estimation1.22.510.12.0-0.21.0-1.01.1-3.2-2.0-2.30.20.0-0.8-0.9-2.0-1.5
Bone: endosteal perimeter1.93.813.12.1-0.41.7-1.72.0-3.6-2.1-3.10.7-0.2-1.4-1.6-1.8-1.9
Bone: final force1.52.44.51.5-2.11.8-1.81.6-0.2-1.5-0.1-0.81.71.9-1.71.6-1.8
Bone: final moment1.72.85.11.8-2.21.8-1.81.7-0.4-1.8-0.2-1.01.92.0-1.81.5-2.0
Bone: marrow area1.22.610.52.1-0.31.1-1.11.2-3.2-2.2-2.40.20.1-0.7-1.0-2.0-1.6
Bone: maximum diameter3.25.810.73.3-2.32.4-2.43.0-3.0-3.2-2.4-0.81.60.7-2.70.1-3.1
Bone: maximum force2.44.16.72.3-2.62.3-2.32.2-1.0-2.3-0.7-1.22.11.8-2.31.5-2.5
Bone: maximum moment2.74.77.52.6-2.72.4-2.42.4-1.2-2.6-0.8-1.32.22.0-2.41.5-2.6
Bone: minimum diameter0.61.03.81.1-0.40.7-0.71.2-2.0-1.1-1.50.60.1-0.6-0.9-0.9-1.1
Bone: periosteal estimation1.43.08.82.3-1.01.6-1.61.8-3.0-2.3-2.2-0.00.7-0.2-1.5-1.2-2.0
Bone: periosteal perimeter2.74.511.22.5-1.42.2-2.22.7-3.3-2.4-2.90.10.5-0.6-2.3-0.9-2.5
Bone: post-yield work0.40.51.20.7-1.10.4-0.40.50.1-0.80.5-0.31.01.0-0.60.9-0.8
Bone: stiffness1.22.03.71.4-1.91.5-1.51.7-0.6-1.4-0.3-0.51.71.1-1.61.4-1.7
Bone: tissue strength0.20.20.40.6-0.50.3-0.30.4-0.4-0.7-0.3-0.30.30.4-0.3-0.1-0.6
Bone: trabecular number0.20.30.6-0.30.50.5-0.50.2-0.40.2-0.70.8-0.8-0.8-0.0-0.60.1
Bone: trabecular spacing0.81.02.00.9-1.41.0-1.01.3-0.3-0.9-0.2-0.50.80.8-1.31.1-1.4
Bone: trabecular thickness0.10.20.5-0.50.4-0.40.4-0.50.20.50.20.30.2-0.10.5-0.10.7
Bone: trabecular tissue density1.11.53.8-0.70.5-1.61.6-1.81.50.81.90.30.70.91.50.11.5
Breakpoint value in progressive ratio session0.20.20.9-0.0-0.3-0.00.0-0.40.70.10.9-0.00.70.50.20.50.3
Distance traveled before self-admin0.80.83.0-0.7-0.6-0.60.60.11.60.61.3-0.80.90.9-0.11.70.3
Distance traveled after self-admin0.40.41.10.8-1.0-0.20.20.20.4-0.80.8-0.11.00.8-0.20.7-0.5
Delta time in closed arm before/after self-admin1.11.02.11.0-1.31.1-1.11.3-0.3-0.9-0.3-0.50.70.5-1.41.4-1.4
Delta time in open arm before/after self-admin0.40.41.2-0.71.0-0.20.2-0.3-0.40.3-0.60.2-0.8-0.50.7-1.10.7
Diff in mean of infusions in LGA sessions0.30.31.1-0.80.3-0.30.3-0.81.00.51.00.3-0.50.30.40.30.4
Extinction: sum of active levers before priming0.10.10.40.0-0.20.3-0.3-0.10.30.20.6-0.20.20.2-0.00.4-0.0
Active lever presses in extinction session 60.30.30.70.5-0.50.8-0.80.10.0-0.30.3-0.80.80.6-0.30.6-0.2
Delta distance traveled before/after self-admin1.01.13.21.7-0.50.7-0.70.7-1.8-1.7-1.30.2-0.1-0.2-0.5-1.1-1.3
Delta ambulatory time before/after self-admin1.31.44.42.1-0.70.6-0.60.7-1.9-2.0-1.2-0.30.10.1-0.5-1.1-1.5
Time in closed arm before self-admin4.55.28.5-2.31.9-2.92.9-2.92.12.32.61.8-0.5-0.52.8-1.02.9
Time in closed arm after self-admin0.20.20.70.3-0.50.4-0.40.4-0.4-0.40.10.70.6-0.1-0.50.8-0.4
Time in open arm before self-admin0.30.31.1-0.10.50.3-0.30.3-0.70.0-1.10.3-0.9-1.0-0.3-0.5-0.3
Time in open arm after self-admin0.70.82.1-1.01.30.1-0.1-0.3-0.50.6-1.10.7-1.3-1.20.7-1.50.8
Sum of active levers in priming session hrs 5-60.10.10.5-0.20.10.0-0.0-0.30.30.30.50.70.20.20.20.00.4
Time to tail flick, vehicle, before self-admin0.20.21.00.60.1-0.10.1-0.2-1.0-0.4-0.5-0.2-0.1-0.2-0.0-0.8-0.3
Time to tail flick, vehicle, after self-admin1.51.65.1-0.71.9-0.40.4-1.0-1.00.8-0.80.7-1.8-1.91.2-2.31.0
Time to tail flick, test, before self-admin0.50.51.6-0.10.6-0.00.00.1-1.20.3-1.2-0.0-1.0-1.3-0.1-0.7-0.2
Time to tail flick, test, after self-admin1.21.22.3-1.31.2-1.11.1-1.00.61.50.71.3-1.0-0.81.2-0.81.2
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.30.20.2-0.2-0.30.50.50.3-0.20.1-0.40.4-0.00.6
Delta time to tail flick, test, before/after SA2.01.83.5-1.21.1-1.91.9-1.61.31.11.51.0-0.50.01.7-0.81.6
Ambulatory time before self-admin0.60.61.9-0.6-0.5-0.80.80.11.30.51.1-0.80.60.6-0.01.40.3
Ambulatory time after self-admin0.20.20.70.3-0.1-0.80.8-0.50.4-0.30.8-0.60.10.10.6-0.30.1
Total heroin consumption0.20.20.70.4-0.60.3-0.3-0.00.3-0.10.7-0.80.50.6-0.20.6-0.4
Area under the delay curve0.20.30.9-0.90.3-0.40.4-0.30.70.90.6-0.2-0.60.10.30.40.2
Delay disc. indifference point, 0s delay0.50.61.50.5-0.90.6-0.60.8-0.5-0.5-0.2-0.71.20.7-0.91.0-0.6
Delay disc. indifference point, 16s delay1.21.22.1-1.41.1-1.01.0-1.11.41.41.11.3-1.1-0.41.2-0.41.1
Delay disc. indifference point, 2s delay0.10.10.7-0.4-0.30.3-0.30.40.20.30.2-0.4-0.10.2-0.40.8-0.3
Delay disc. indifference point, 24s delay0.40.42.7-0.40.50.1-0.10.0-0.30.7-0.60.3-1.7-0.80.1-0.9-0.4
Delay disc. indifference point, 4s delay0.50.61.90.2-0.8-0.30.30.00.8-0.01.0-1.40.91.3-0.21.1-0.3
Delay disc. indifference point, 8s delay0.80.82.5-1.50.8-0.80.8-0.71.11.60.90.3-1.0-0.30.80.10.8
Delay discount exponential model param0.30.30.90.9-0.30.5-0.50.3-0.6-1.0-0.60.30.70.0-0.3-0.3-0.3
Delay discount hyperbolic model param0.20.20.60.7-0.10.3-0.30.1-0.5-0.7-0.50.50.4-0.1-0.1-0.4-0.1
Fecal boli incidents, locomotor time 10.20.30.6-0.60.4-0.40.4-0.70.60.50.80.6-0.3-0.10.6-0.10.5
Change in fecal boli incidents, locomotor task0.90.92.60.7-0.10.7-0.71.1-1.3-0.7-1.6-0.6-1.1-0.5-0.7-0.9-1.2
Time >=10cm from walls, locomotor time 10.00.00.1-0.1-0.20.3-0.30.2-0.20.0-0.10.40.10.2-0.20.0-0.3
Bouts of movement, locomotor time 10.20.31.1-0.1-0.21.1-1.10.50.00.1-0.4-0.2-0.2-0.0-0.70.5-0.4
Total resting periods, locomotor time 10.20.30.9-0.5-0.20.8-0.80.20.70.50.30.2-0.10.2-0.40.9-0.1
Rest time, locomotor task time 10.70.73.6-0.3-0.91.0-1.00.61.00.10.80.30.70.9-0.71.9-0.3
Distance moved, locomotor task time 10.50.51.90.8-0.20.3-0.30.8-1.4-0.7-1.3-0.80.3-0.1-0.6-0.5-0.7
Vertical activity count, locomotor time 10.10.10.90.3-0.0-0.30.30.0-0.3-0.2-0.4-1.00.30.30.1-0.50.0
Time >=10cm from walls, locomotor time 20.30.32.2-0.50.4-0.60.6-0.3-0.10.40.31.5-0.5-0.40.5-0.40.2
Bouts of movement, locomotor time 20.60.62.10.1-0.90.9-0.90.60.7-0.30.6-0.40.81.1-0.61.4-0.4
Total resting periods, locomotor time 20.60.62.20.0-0.90.8-0.80.50.9-0.30.8-0.40.81.2-0.61.5-0.4
Rest time, locomotor task time 20.10.10.5-0.50.00.0-0.0-0.30.70.30.7-0.2-0.20.30.20.40.1
Distance moved, locomotor task time 20.50.51.70.6-0.40.5-0.51.1-1.3-0.5-1.2-0.50.4-0.4-0.90.1-0.7
Vertical activity count, locomotor time 20.30.30.90.6-0.30.4-0.40.7-0.9-0.6-0.9-0.00.4-0.0-0.5-0.2-0.5
Weight adjusted by age0.40.41.70.40.4-0.40.4-0.1-1.1-0.4-0.80.1-0.9-0.70.1-1.3-0.4
Seeking ratio, delayed vs. immediate footshock2.83.25.4-2.31.4-1.91.9-2.02.32.32.21.7-0.7-0.42.0-0.32.1
Locomotion in novel chamber1.51.86.0-0.51.7-1.11.1-0.3-1.30.6-0.81.4-1.8-2.51.2-2.00.8
Locomotion in novel chamber post-restriction1.31.54.1-1.51.3-1.01.0-0.90.61.70.52.0-1.2-1.51.1-0.61.2
Progressive ratio0.20.31.1-0.0-0.1-0.40.4-0.50.60.10.8-1.10.70.50.30.20.5
Food seeking constrained by brief footshock1.31.63.21.2-1.31.4-1.41.8-1.1-1.1-1.2-1.30.60.2-1.50.8-1.6
Seeking ratio, punishment vs. effort0.50.71.70.6-0.81.0-1.01.3-0.7-0.6-0.90.30.0-0.0-1.10.6-1.2
Run reversals in cocaine runway, females1.31.22.8-1.01.4-1.01.0-0.7-0.70.7-0.41.2-1.7-1.50.9-1.70.7
Run reversals in cocaine runway, males1.21.23.31.0-0.21.0-1.00.9-1.5-1.0-1.8-1.6-0.7-0.4-0.8-0.7-1.1
Latency to leave start box in cocaine runway0.20.20.60.2-0.30.8-0.80.4-0.2-0.3-0.30.30.40.1-0.50.4-0.2
Latency to leave start box in cocaine runway, F0.20.30.9-0.60.6-0.30.3-0.70.20.40.30.9-0.3-0.30.6-0.30.7
Latency to leave start box in cocaine runway, M1.91.83.71.1-1.51.9-1.91.6-0.3-1.0-0.7-1.01.31.1-1.61.4-1.3
Cd content in liver0.70.82.21.5-0.50.7-0.70.9-1.2-1.4-0.9-0.90.2-0.3-0.90.0-0.9
Co content in liver0.40.51.11.1-0.90.6-0.60.5-0.1-1.00.1-0.50.90.9-0.60.9-0.6
Cu content in liver3.23.96.2-2.51.8-2.52.5-2.31.72.51.61.8-1.1-0.62.3-0.62.3
Fe content in liver0.20.20.80.80.0-0.10.1-0.0-0.9-0.8-0.70.10.5-0.10.1-0.8-0.0
K content in liver0.50.51.4-0.4-0.0-0.90.9-0.91.00.51.20.10.50.80.70.40.5
Mg content in liver1.11.23.0-1.2-0.0-1.21.2-1.11.61.11.70.90.60.91.00.80.8
Mn content in liver0.20.20.60.30.10.4-0.40.5-0.80.0-0.7-0.2-0.6-0.7-0.4-0.3-0.5
Na content in liver2.22.33.7-1.81.4-1.81.8-1.91.51.81.41.1-0.8-0.31.8-0.41.9
Rb content in liver0.10.10.30.1-0.4-0.40.4-0.00.3-0.00.2-0.40.40.5-0.10.3-0.2
Se content in liver0.60.71.3-0.91.1-0.80.8-1.00.20.80.10.6-0.9-0.81.0-1.00.9
Sr content in liver0.80.71.5-1.21.0-0.70.7-0.90.81.20.60.4-0.9-0.70.9-0.01.1
Zn content in liver1.11.22.5-1.11.2-1.61.6-1.20.31.00.31.1-0.9-0.91.3-1.01.1