Pmm1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000005358 0.12 0.05 1.7e-16 0.11 0.12 0.12 0.12 1.7e-12 1.7e-13 2.0e-13 4.9e-13
2 BLA gene expression ENSRNOG00000005358 0.33 0.14 1.7e-16 0.25 0.28 0.28 0.28 1.4e-13 4.5e-15 3.7e-15 3.5e-15
3 Brain gene expression ENSRNOG00000005358 0.44 0.12 0.0e+00 0.52 0.54 0.55 0.55 2.7e-55 2.3e-58 2.4e-60 6.0e-61
4 Brain mRNA stability ENSRNOG00000005358 0.05 0.03 1.5e-05 0.07 0.05 0.06 0.06 3.6e-07 1.3e-05 7.9e-06 2.1e-06
5 IL gene expression ENSRNOG00000005358 0.23 0.12 4.4e-04 0.03 0.08 0.05 0.05 8.3e-02 6.8e-03 2.7e-02 3.0e-02
6 LHb gene expression ENSRNOG00000005358 0.27 0.12 5.9e-06 0.22 0.26 0.22 0.22 7.4e-06 6.8e-07 5.4e-06 4.9e-06
7 NAcc gene expression ENSRNOG00000005358 0.2 0.09 2.4e-13 0.11 0.15 0.14 0.15 2.2e-08 2.9e-11 1.1e-10 5.6e-11
8 OFC gene expression ENSRNOG00000005358 0.47 0.16 8.2e-07 0.09 0.14 0.16 0.09 3.2e-03 2.7e-04 1.2e-04 4.0e-03
9 PL gene expression ENSRNOG00000005358 0.2 0.08 0.0e+00 0.26 0.24 0.24 0.25 9.5e-20 3.8e-18 1.7e-18 7.4e-19
10 PL mRNA stability ENSRNOG00000005358 0.03 0.02 7.7e-03 0.03 0.01 0.01 0.02 1.4e-03 2.8e-02 2.9e-02 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail1.13.66.3-1.6-2.4-1.32.3-1.1-2.4-1.1-0.8-2.52.4
BMI without tail0.10.10.3-0.3-0.5-0.00.10.5-0.10.50.5-0.50.3
Body weight1.56.59.6-2.4-2.9-2.62.6-2.1-2.6-2.0-1.7-3.03.1
Epididymis fat weight4.19.511.6-3.4-3.0-3.42.9-3.0-2.9-2.9-3.4-3.03.0
Glucose0.71.01.90.90.71.0-0.51.40.71.31.40.8-0.8
Heart weight1.52.24.6-1.3-2.1-0.92.2-0.6-2.0-0.7-0.6-1.81.4
Left kidney weight12.435.740.9-5.7-6.4-5.86.3-5.8-5.9-6.0-5.1-6.36.3
Right kidney weight13.036.943.4-5.8-6.6-5.76.6-5.9-6.2-6.0-4.9-6.46.5
Tail length0.10.30.80.20.50.2-0.80.60.90.60.20.6-0.7
Length with tail0.41.63.1-1.3-1.2-1.81.0-1.4-0.8-1.4-1.2-1.11.4
Length without tail1.43.14.2-1.3-1.6-1.81.7-2.0-1.6-2.0-1.6-1.72.0
Liver weight, left1.21.93.7-1.8-1.2-1.91.2-1.4-0.8-1.4-1.5-1.11.1
Liver weight, right3.15.28.1-2.9-2.1-2.62.1-2.2-1.8-2.1-2.6-2.12.1
Parametrial fat weight0.10.20.5-0.2-0.4-0.00.7-0.1-0.7-0.1-0.4-0.70.6
Retroperitoneal fat weight4.113.618.3-3.6-3.7-3.63.8-3.3-3.8-3.3-3.5-3.94.3
Intraocular pressure0.60.91.7-0.9-0.6-1.10.5-1.2-0.7-1.2-1.3-1.00.8
Extensor digitorum longus weight0.20.91.30.50.80.9-0.71.11.01.10.91.1-1.1
Soleus weight0.10.40.80.90.70.8-0.40.20.50.10.60.7-0.7
Tibialis anterior weight0.82.83.91.91.52.0-1.51.81.21.81.61.6-1.6
Tibia length0.92.53.7-1.3-1.6-1.81.5-1.9-1.3-1.9-1.2-1.61.6
Number of licking bursts0.30.40.70.70.70.6-0.80.20.80.20.40.7-0.8
Food consumed during 24 hour testing period1.41.63.3-0.9-1.5-1.01.4-0.9-1.5-0.9-0.6-1.71.8
Times rat made contact with spout0.60.71.2-0.5-0.9-0.41.0-0.9-1.0-0.8-0.7-0.91.1
Mean time between licks in bursts0.71.01.40.91.11.0-0.91.00.71.20.91.1-1.2
Mean num. licks in bursts1.82.22.9-1.4-1.6-1.31.7-1.2-1.6-1.2-1.4-1.51.7
Std. dev. time between licks in bursts1.92.23.61.61.51.5-1.31.31.31.21.91.5-1.5
Water consumed over 24 hours0.91.11.7-0.8-1.2-1.00.9-1.1-0.8-1.1-0.7-1.11.3
Indifference point 0 sec0.71.12.41.20.81.1-0.61.20.91.11.50.8-1.0
Indifference point AUC0.20.20.40.40.60.1-0.3-0.60.3-0.7-0.40.4-0.1
Indifference point function ln k0.81.12.0-1.2-1.4-1.21.2-0.6-1.1-0.6-0.6-1.31.0
Indifference point function log k0.81.12.0-1.2-1.4-1.21.2-0.6-1.1-0.6-0.6-1.31.0
Delay discounting total patch changes 0 sec0.81.42.51.30.91.2-0.81.31.01.21.61.0-1.1
Delay discounting total patch changes 12 sec0.00.10.20.40.30.20.10.00.1-0.10.40.20.1
Delay discounting total patch changes 18 sec0.20.30.90.90.40.6-0.20.40.30.41.00.5-0.5
Delay discounting total patch changes 24 sec0.20.30.60.60.80.5-0.50.30.60.20.30.8-0.6
Delay discounting total patch changes 6 sec0.40.61.41.00.71.1-0.40.50.70.41.20.9-0.7
Delay discounting time to switch 0 sec0.10.20.6-0.00.4-0.1-0.10.70.20.80.60.2-0.1
Delay discounting water rate 0 sec0.20.30.80.7-0.00.9-0.40.50.50.40.70.4-0.5
Delay discounting water rate 12 sec0.40.51.10.50.30.5-1.10.60.90.50.70.8-1.0
Delay discounting water rate 18 sec1.41.83.31.31.21.1-1.81.11.70.91.41.4-1.3
Delay discounting water rate 24 sec0.00.00.30.1-0.50.1-0.20.20.1-0.00.3-0.10.1
Delay discounting water rate 6 sec0.60.92.20.60.80.6-1.30.51.50.40.61.2-1.3
Locomotor activity2.03.24.3-2.0-2.1-2.01.6-1.6-1.4-1.7-1.5-1.82.0
Locomotor testing distance0.00.00.10.00.00.0-0.3-0.00.20.0-0.10.0-0.1
Locomotor testing rearing1.52.33.0-1.7-1.6-1.51.6-1.4-1.5-1.3-1.5-1.61.3
Light reinforcement 10.10.20.6-0.8-0.2-0.70.3-0.70.2-0.7-0.20.1-0.4
Light reinforcement 20.70.91.4-1.2-0.9-0.91.1-0.8-1.0-0.8-0.9-0.90.7
Reaction time number correct0.71.02.90.51.10.4-1.70.21.40.3-0.01.1-1.5
Reaction time mean minus median0.10.20.6-0.8-0.5-0.50.5-0.1-0.3-0.1-0.4-0.20.1
Reaction time mean minus median AUC0.60.81.4-1.2-1.0-1.01.0-0.5-1.0-0.4-1.0-0.90.9
Reaction time num false alarms0.10.10.5-0.70.0-0.4-0.2-0.10.4-0.1-0.30.4-0.4
Reaction time num false alarms AUC0.10.20.5-0.60.2-0.2-0.3-0.20.6-0.2-0.30.7-0.6
Reaction time trials correct on left0.71.02.90.51.10.4-1.70.21.40.3-0.01.1-1.5
Reaction time trials on left0.81.13.10.51.10.5-1.80.21.40.3-0.01.2-1.5
Reaction time mean0.20.30.70.30.30.4-0.40.70.30.70.60.6-0.8
Reaction time mean AUC0.20.20.50.30.30.4-0.40.60.30.60.40.5-0.7
Median of all reaction times0.50.71.20.70.60.7-0.81.00.60.90.80.8-1.1
Reaction time omissions0.20.20.90.10.40.3-0.60.20.60.20.00.6-0.9
Reaction time false alarm rate0.10.10.5-0.7-0.3-0.30.6-0.1-0.3-0.2-0.20.10.2
Reaction time premature initiation rate0.50.72.11.00.71.0-0.40.90.60.81.50.7-0.3
Reaction time premature initiations0.60.81.21.00.91.0-1.00.81.00.71.10.9-0.7
Std. dev. reaction times0.30.40.9-0.9-0.8-0.80.8-0.4-0.6-0.4-0.5-0.50.2
Reaction time trials completed0.81.13.10.51.10.5-1.80.21.40.3-0.01.2-1.5
Reaction time trials AUC0.60.82.50.40.90.3-1.60.21.30.2-0.11.0-1.4
Social response proportion0.30.41.00.3-0.40.30.51.0-0.31.00.9-0.20.3
Social responses0.00.00.2-0.10.2-0.0-0.1-0.10.4-0.1-0.00.4-0.1
Social time2.12.84.21.81.72.0-1.51.71.41.71.61.6-1.6
Conditioned locomotion0.80.91.6-1.3-0.8-1.21.1-0.9-0.8-0.8-1.0-0.80.6
Cocaine response after cond. corrected0.10.10.1-0.4-0.2-0.30.1-0.3-0.1-0.2-0.3-0.10.3
Cocaine response after cond. not corrected0.00.00.2-0.4-0.1-0.20.1-0.00.1-0.0-0.00.20.0
Cocaine response before conditioning0.20.20.40.20.50.60.00.60.40.60.60.6-0.5
Saline control response0.20.31.0-1.0-0.2-0.50.5-0.30.2-0.5-0.70.3-0.2
Condit. Reinf. active minus inactive responses0.10.10.40.60.10.20.0-0.3-0.1-0.40.3-0.1-0.1
Condit. Reinf. active-inactive response ratio0.10.10.40.7-0.10.20.0-0.2-0.3-0.20.5-0.40.3
Condit. Reinf. active responses0.50.61.6-0.4-0.6-0.70.9-1.2-0.7-1.3-0.5-0.70.4
Condit. Reinf. inactive responses1.21.42.4-1.2-0.9-1.11.4-1.6-1.0-1.5-1.2-0.90.8
Condit. Reinf. lever presses0.40.51.11.00.60.8-0.30.60.60.51.10.6-0.7
Condit. Reinf. lever reinforcers received0.20.20.8-0.1-0.4-0.40.6-0.8-0.4-0.9-0.1-0.40.2
Pavlov. Cond. lever latency1.52.04.5-1.5-1.2-1.21.1-1.5-1.4-1.4-2.1-1.31.4
Pavlov. Cond. magazine entry latency4.85.59.03.02.12.5-2.42.51.92.32.72.0-1.9
Pavlov. Cond. change in total contacts1.41.96.21.90.81.4-0.71.50.81.32.50.8-0.8
Pavlov. Cond. index score3.24.26.92.51.82.1-1.82.21.72.02.61.8-1.7
Pavlov. Cond. latency score4.05.08.02.81.92.4-2.02.31.92.22.81.9-1.9
Pavlov. Cond. lever contacts1.42.04.81.61.11.3-0.91.61.31.42.21.2-1.2
Pavlov. Cond. magazine entry number2.43.05.6-2.4-1.5-1.81.8-1.8-1.4-1.6-2.1-1.41.3
Pavlov. Cond. intertrial magazine entries2.53.26.5-1.5-1.8-1.02.6-1.5-2.3-1.4-1.5-1.91.9
Pavlov. Cond. lever-magazine prob. diff.3.34.26.92.51.82.1-1.82.21.82.02.61.8-1.7
Pavlov. Cond. response bias1.72.35.51.91.21.4-1.11.71.31.52.31.2-1.2
Conditioned reinforcement - actives0.70.72.0-0.7-0.7-0.60.5-1.4-0.6-1.4-1.0-0.60.4
Conditioned reinforcement - inactives0.20.20.80.70.20.8-0.10.30.00.30.90.1-0.5
Conditioned locomotion1.72.13.0-1.1-1.5-1.11.6-1.6-1.7-1.5-0.8-1.71.5
Intermittent access intake day 1-15 change0.30.30.60.70.50.8-0.60.40.50.50.40.6-0.6
Intermittent access intake escalation0.50.50.80.80.60.9-0.60.60.60.60.50.8-0.7
Intermittent access intake escalation 20.20.20.50.30.40.5-0.30.40.40.40.30.6-0.7
Intermitt. access day 1 inactive lever presses0.20.30.60.2-0.80.20.80.2-0.60.10.7-0.40.3
Intermitt. access day 15 inactive lever presses0.50.51.30.3-0.90.31.1-0.3-1.1-0.40.2-0.80.8
Intermitt. access escalation Index0.20.20.80.60.10.4-0.00.30.00.40.90.1-0.0
Intermittent access day 1 total infusions0.91.11.7-0.7-1.2-0.81.0-1.1-1.2-1.1-0.6-1.31.0
Intermittent access day 15 total infusions0.00.00.20.4-0.20.4-0.0-0.1-0.2-0.10.3-0.1-0.0
Intermittent access terminal intake (last 3 days)0.10.10.2-0.2-0.3-0.10.2-0.4-0.3-0.4-0.3-0.20.1
Intermittent access total infusions0.20.20.5-0.2-0.6-0.30.4-0.5-0.7-0.5-0.2-0.60.5
Intermittent access day 1 locomotion0.30.30.6-0.3-0.7-0.20.5-0.3-0.8-0.30.0-0.80.6
Intermittent access day 15 total locomotion0.10.10.2-0.2-0.5-0.30.1-0.4-0.4-0.4-0.2-0.40.3
Intermittent access total locomotion0.30.30.8-0.2-0.7-0.30.5-0.5-0.9-0.4-0.2-0.90.8
Intermittent access standard deviation0.40.41.0-0.3-0.9-0.31.0-0.2-1.0-0.2-0.1-0.80.6
Cocaine induced anxiety0.40.51.4-0.2-0.8-0.20.8-0.0-1.2-0.1-0.3-0.81.1
Post-drug Anxiety0.10.10.40.1-0.3-0.30.30.1-0.40.00.3-0.20.6
Baseline Anxiety0.80.81.80.71.20.5-1.10.51.40.60.71.1-0.9
Lifetime Intake0.60.71.5-0.2-1.0-0.30.9-0.7-1.2-0.6-0.2-1.10.9
Incentive Sensitization - Responses0.30.31.40.90.41.2-0.40.30.20.30.50.3-0.5
Incentive Sensitization - Breakpoint0.20.21.10.80.21.0-0.20.2-0.00.10.40.1-0.3
Progressive ratio test 1 active lever presses0.40.41.1-0.1-0.70.00.7-0.6-1.0-0.6-0.4-0.70.6
Progressive ratio test 1 breakpoint0.30.30.8-0.1-0.60.00.5-0.6-0.9-0.5-0.5-0.60.5
Progressive ratio test 1 inactive lever presses0.40.41.10.5-0.70.80.80.5-1.10.40.6-0.60.3
Progressive ratio test 2 active lever presses0.10.10.60.60.00.8-0.1-0.3-0.3-0.3-0.1-0.0-0.1
Progressive ratio test 2 breakpoint0.10.10.60.6-0.10.80.1-0.2-0.5-0.3-0.0-0.20.1
Progressive ratio test 2 inactive lever presses0.60.72.31.40.41.5-0.30.80.00.60.80.5-0.7
Total sessions with >9 infusions1.41.62.7-0.7-1.4-0.71.5-1.3-1.6-1.2-0.6-1.51.5
Short access day 1 total inactive lever presses0.91.01.9-0.6-1.4-0.81.3-1.0-1.1-1.0-0.1-1.30.9
Short access day 10 total inactive lever presses0.50.50.9-0.8-1.0-1.00.8-0.7-0.6-0.8-0.4-0.70.6
Short access day 1 total infusions1.31.42.7-0.7-1.5-0.61.6-1.0-1.6-1.0-0.3-1.41.1
Short access day 10 total infusions0.50.61.5-0.3-0.9-0.20.9-0.4-1.2-0.3-0.3-1.21.0
Short access total infusions1.81.94.3-0.6-1.7-0.61.8-1.0-2.1-0.9-0.3-1.91.7
Short access day 1 locomotion0.20.20.60.1-0.40.40.70.2-0.70.20.5-0.60.3
Short access day 10 total locomotion0.20.30.80.20.00.40.30.8-0.20.90.9-0.30.1
Short access total locomotion0.90.92.3-0.4-1.1-0.21.4-0.3-1.5-0.20.2-1.41.1
Compulsive drug intake1.51.52.51.41.61.1-1.60.61.60.50.61.3-1.3
One hour access (0.3 mA shock)0.20.20.50.60.50.7-0.60.30.30.40.30.4-0.5
One hour access (shock baseline)0.10.10.3-0.2-0.3-0.00.30.0-0.60.1-0.2-0.20.3
Number of responses in last shaping day1.92.04.31.71.02.1-0.41.60.51.71.90.9-1.0
Context. condit. distance diff. score7.49.011.2-3.3-3.1-3.13.1-2.8-2.8-2.8-3.1-2.82.9
Locomotion velocity, session 10.40.51.6-0.5-0.0-0.8-0.3-1.20.4-1.3-0.60.0-0.1
Locomotion distance, session 11.62.14.11.31.91.0-2.00.41.90.50.71.7-1.8
Locomotion velocity, session 20.20.30.5-0.7-0.5-0.50.6-0.6-0.2-0.6-0.2-0.50.4
Locomotion distance, session 22.73.95.82.42.12.1-2.01.61.81.62.11.8-2.0
Locomotion velocity, session 30.50.61.3-1.1-0.3-1.00.2-1.1-0.2-1.1-1.2-0.30.5
Locomotion distance, session 30.60.71.80.41.20.4-1.4-0.21.1-0.1-0.41.0-0.9
Stereotopy head waving bouts, day 30.80.91.3-1.0-1.1-1.21.0-0.9-0.8-1.0-0.6-1.01.0
Stereotopy head waving duration, day 33.13.75.2-2.3-2.1-2.32.2-1.7-1.6-1.8-1.2-1.91.9
Locomotion velocity, session 70.30.30.6-0.6-0.3-0.50.2-0.7-0.4-0.6-0.8-0.70.6
Locomotion distance, session 70.10.10.50.60.40.7-0.30.1-0.30.2-0.2-0.20.1
Stereotopy head waving bouts, day 73.54.08.0-2.6-1.9-2.81.6-2.2-1.0-2.3-1.7-1.61.6
Stereotopy head waving duration, day 72.43.06.1-2.4-1.8-2.51.5-1.7-0.9-1.7-1.5-1.31.4
Locomotion velocity, session 82.12.63.7-1.6-1.7-1.61.9-1.7-1.4-1.8-1.2-1.51.4
Locomotion distance, session 80.91.32.0-1.4-1.1-1.21.3-1.1-1.0-1.2-1.2-0.90.9
Degree of sensitization distance1.61.73.8-0.7-1.6-0.51.9-0.2-2.0-0.2-0.3-1.71.6
Degree of sensitization stereotypy2.73.06.3-2.2-1.6-2.51.2-2.0-0.8-2.0-1.7-1.31.3
Condit. Reinf. active minus inactive responses0.30.30.60.80.70.7-0.50.40.30.30.70.3-0.4
Condit. Reinf. active-inactive response ratio0.30.30.6-0.5-0.4-0.50.5-0.7-0.5-0.7-0.5-0.60.5
Condit. Reinf. active responses1.82.23.51.61.61.9-1.21.51.11.41.51.4-1.5
Condit. Reinf. inactive responses3.44.05.51.92.02.3-1.62.21.62.11.82.0-2.2
Incentive salience index mean0.70.91.61.31.11.2-0.60.80.50.81.20.6-0.7
Condit. Reinf. lever presses1.01.42.11.31.41.4-0.71.20.81.21.40.9-1.1
Time in familiar zone, hab. session 10.30.20.8-0.3-0.0-0.50.1-0.9-0.2-0.8-0.6-0.30.4
Time in novel zone, hab. session 10.40.41.1-0.9-1.1-0.70.80.1-0.50.0-0.1-0.40.4
Total zone transitions, hab. session 12.33.25.71.62.21.4-2.40.82.30.80.82.2-2.2
Total locomotion distance, hab. session 11.01.43.60.31.50.5-1.60.11.90.00.01.7-1.7
Locomotion velocity, hab. session 11.42.04.10.81.80.9-1.70.42.00.40.51.9-2.0
Time in familiar zone, hab. session 20.20.20.6-0.80.1-0.50.0-0.40.1-0.3-0.70.10.0
Time in novel zone, hab. session 20.10.10.20.3-0.50.20.20.1-0.1-0.10.3-0.20.0
Total zone transitions, hab. session 20.71.01.51.21.10.9-0.90.41.10.31.11.1-1.2
Total locomotion distance, hab. session 20.81.11.51.01.11.0-0.90.71.10.71.21.1-1.2
Locomotion velocity, hab. session 21.41.92.61.31.51.4-1.21.01.51.01.51.5-1.6
Novel to familiar place preference ratio3.23.35.2-2.0-2.2-2.31.3-1.7-1.2-1.8-1.8-1.71.8
Novelty place preference4.54.76.7-2.4-2.5-2.61.6-2.1-1.5-2.2-2.2-2.02.1
Time in novel zone, NPP test5.55.88.0-2.7-2.8-2.81.8-2.3-1.7-2.4-2.5-2.32.3
Total zone transitions, NPP test2.02.84.61.52.11.3-2.00.62.10.60.92.1-2.1
Total locomotion distance, NPP test1.11.52.31.21.51.0-1.50.61.50.60.91.5-1.5
Locomotion velocity, NPP test1.82.53.91.52.01.4-1.81.01.91.01.21.9-1.9
Pavlov. Cond. lever latency1.31.62.5-1.4-1.4-1.61.0-1.3-1.0-1.3-1.4-1.11.2
Pavlov. Cond. magazine entry latency1.21.53.11.61.31.8-1.01.20.61.31.30.9-0.9
Pavlov. Cond. change in total contacts1.81.93.61.81.31.9-1.01.30.81.31.71.0-1.1
Pavlov. Cond. index score0.70.92.31.30.91.5-0.51.00.21.01.10.4-0.5
Pavlov. Cond. latency score0.60.82.11.20.81.4-0.51.00.31.01.10.4-0.6
Pavlov. Cond. lever contacts1.72.03.71.61.51.9-1.11.50.91.51.51.1-1.3
Pavlov. Cond. magazine entry number0.70.82.2-1.3-1.0-1.50.7-0.9-0.4-0.9-0.8-0.50.6
Pavlov. Cond. intertrial magazine entries1.11.31.81.31.01.1-1.31.01.10.91.21.2-1.1
Pavlov. Cond. lever-magazine prob. diff.0.81.02.51.41.11.6-0.71.00.41.01.10.6-0.7
Pavlov. Cond. response bias1.21.53.21.61.31.8-0.81.30.51.31.30.7-0.8
Bone: apparent density0.30.50.80.80.60.5-0.90.90.70.80.90.6-0.5
Bone surface0.10.20.80.10.3-0.1-0.6-0.20.9-0.30.30.6-0.3
Bone volume0.00.00.2-0.10.1-0.1-0.2-0.10.4-0.10.10.2-0.0
Bone: connectivity density0.10.20.40.60.30.2-0.60.50.40.40.60.2-0.0
Bone: cortical apparent density0.50.61.11.01.00.7-0.90.50.80.50.70.7-0.9
Bone: cortical area1.42.12.7-1.4-1.5-1.51.6-1.4-1.4-1.4-0.8-1.61.5
Bone: cortical porosity0.30.30.8-0.9-0.6-0.60.9-0.2-0.6-0.2-0.3-0.60.6
Bone: cortical porosity1.01.01.6-1.3-1.2-1.21.2-0.6-1.0-0.6-0.5-1.21.1
Bone: cortical thickness0.20.30.70.3-0.40.10.6-0.1-0.8-0.10.3-0.80.7
Bone: cortical thickness0.20.30.90.1-0.50.20.8-0.3-0.9-0.3-0.0-0.70.6
Bone: cortical tissue density0.40.61.01.00.90.7-0.90.40.80.40.60.7-0.9
Bone: elastic displacement0.20.30.7-0.7-0.4-0.8-0.1-0.60.2-0.7-0.5-0.20.1
Bone: elastic work1.72.23.2-1.6-1.8-1.71.5-1.2-1.3-1.3-0.8-1.61.7
Bone: endosteal estimation1.12.35.2-2.3-1.5-2.11.4-1.7-0.5-1.8-1.3-0.91.0
Bone: endosteal perimeter2.34.78.8-3.0-2.0-2.91.9-2.3-1.2-2.3-1.9-1.71.8
Bone: final force1.11.83.4-0.7-1.5-1.01.6-1.1-1.6-1.2-0.5-1.81.8
Bone: final moment1.22.13.5-0.9-1.7-1.11.7-1.2-1.7-1.3-0.6-1.81.9
Bone: marrow area1.22.55.5-2.3-1.5-2.11.5-1.7-0.5-1.9-1.4-0.91.1
Bone: maximum diameter4.07.38.9-2.9-2.9-3.03.0-2.6-2.4-2.7-1.9-2.72.7
Bone: maximum force2.23.85.6-1.5-2.2-1.62.3-1.7-2.2-1.7-1.0-2.32.4
Bone: maximum moment2.44.26.0-1.6-2.4-1.72.4-1.8-2.3-1.9-1.1-2.42.4
Bone: minimum diameter0.71.22.4-1.6-1.0-1.51.1-1.2-0.7-1.3-0.9-0.80.8
Bone: periosteal estimation1.73.45.7-2.4-1.9-2.31.9-1.9-1.2-2.0-1.4-1.51.6
Bone: periosteal perimeter4.06.69.8-3.1-2.6-3.12.5-2.6-2.0-2.5-2.1-2.52.5
Bone: post-yield work0.10.20.6-0.0-0.40.00.8-0.3-0.6-0.30.3-0.40.4
Bone: stiffness1.11.83.2-1.0-1.5-1.01.8-1.0-1.7-1.0-0.5-1.71.7
Bone: tissue strength0.10.10.2-0.2-0.4-0.40.1-0.4-0.2-0.5-0.1-0.20.4
Bone: trabecular number0.10.10.3-0.4-0.1-0.6-0.2-0.30.0-0.2-0.4-0.20.4
Bone: trabecular spacing0.91.22.1-0.7-1.1-0.81.2-1.1-1.3-1.0-0.6-1.41.3
Bone: trabecular thickness0.30.30.60.30.50.5-0.50.80.50.70.50.7-0.6
Bone: trabecular tissue density2.33.24.41.81.42.0-1.42.11.52.02.11.8-1.8
Breakpoint value in progressive ratio session0.30.30.60.60.30.8-0.40.70.20.70.80.1-0.5
Distance traveled before self-admin0.30.30.90.80.10.90.20.7-0.50.70.6-0.2-0.0
Distance traveled after self-admin0.10.21.10.5-0.20.30.10.2-0.20.21.1-0.2-0.0
Delta time in closed arm before/after self-admin1.41.43.0-0.9-1.0-0.61.7-1.2-1.5-1.1-1.0-1.21.0
Delta time in open arm before/after self-admin0.20.20.70.00.3-0.3-0.80.40.70.30.20.4-0.6
Diff in mean of infusions in LGA sessions0.30.40.80.90.70.9-0.70.40.40.40.40.7-0.4
Extinction: sum of active levers before priming0.00.00.30.20.20.5-0.00.1-0.10.10.10.0-0.1
Active lever presses in extinction session 60.10.00.2-0.1-0.20.20.40.1-0.40.0-0.0-0.20.2
Delta distance traveled before/after self-admin0.70.81.9-1.0-0.8-1.30.5-1.3-0.1-1.4-0.5-0.40.3
Delta ambulatory time before/after self-admin0.80.82.2-1.0-0.8-1.30.6-1.4-0.0-1.5-0.4-0.40.2
Time in closed arm before self-admin7.48.411.12.72.72.8-2.63.32.73.33.32.9-2.7
Time in closed arm after self-admin0.20.31.2-0.5-0.4-0.11.1-0.1-0.70.0-0.0-0.40.5
Time in open arm before self-admin0.40.41.6-0.7-0.2-0.70.1-0.8-0.2-0.8-1.3-0.30.5
Time in open arm after self-admin0.20.20.9-0.20.4-0.6-1.00.20.80.2-0.30.2-0.4
Sum of active levers in priming session hrs 5-60.10.10.30.20.20.4-0.00.50.20.50.40.2-0.3
Time to tail flick, vehicle, before self-admin0.10.10.4-0.5-0.0-0.30.2-0.50.2-0.6-0.40.30.1
Time to tail flick, vehicle, after self-admin0.60.72.1-0.10.9-0.0-1.40.31.40.2-0.11.2-0.8
Time to tail flick, test, before self-admin0.40.41.3-0.9-0.0-0.90.1-0.8-0.1-0.8-1.2-0.00.4
Time to tail flick, test, after self-admin1.01.11.80.91.30.9-0.70.91.21.01.01.2-1.1
Delta time to tail flick, vehicle, before/after SA0.20.20.50.40.30.4-0.70.70.30.70.40.1-0.1
Delta time to tail flick, test, before/after SA3.12.83.51.71.51.7-1.31.61.71.61.91.7-1.9
Ambulatory time before self-admin0.20.20.70.70.10.80.00.5-0.30.50.5-0.3-0.1
Ambulatory time after self-admin0.40.51.50.90.50.5-0.70.30.80.31.20.5-0.7
Total heroin consumption0.00.00.10.2-0.00.4-0.0-0.1-0.2-0.20.0-0.2-0.2
Area under the delay curve0.20.20.40.60.60.6-0.40.00.20.10.10.5-0.4
Delay disc. indifference point, 0s delay0.50.61.5-0.8-0.8-0.41.2-0.2-1.1-0.2-0.2-0.80.8
Delay disc. indifference point, 16s delay1.31.42.01.41.31.2-1.40.81.20.90.81.3-1.2
Delay disc. indifference point, 2s delay0.10.10.4-0.1-0.1-0.00.5-0.4-0.6-0.3-0.3-0.50.5
Delay disc. indifference point, 24s delay0.40.41.20.10.5-0.4-0.7-1.10.3-1.0-0.70.2-0.2
Delay disc. indifference point, 4s delay0.10.10.40.60.10.60.30.1-0.20.00.50.1-0.2
Delay disc. indifference point, 8s delay0.70.71.41.01.21.0-1.00.50.60.60.40.9-0.8
Delay discount exponential model param0.20.20.5-0.6-0.7-0.60.40.0-0.2-0.0-0.1-0.50.5
Delay discount hyperbolic model param0.10.10.2-0.4-0.5-0.50.20.1-0.00.1-0.0-0.30.3
Fecal boli incidents, locomotor time 10.40.40.50.70.70.7-0.60.60.60.60.60.7-0.5
Change in fecal boli incidents, locomotor task1.41.33.1-1.0-0.7-1.60.4-1.8-0.5-1.7-1.3-0.70.9
Time >=10cm from walls, locomotor time 10.00.00.1-0.1-0.0-0.3-0.0-0.1-0.2-0.10.0-0.20.3
Bouts of movement, locomotor time 10.40.41.2-0.4-0.5-0.40.1-0.6-0.7-0.6-1.1-0.70.9
Total resting periods, locomotor time 10.10.10.50.1-0.10.1-0.1-0.1-0.6-0.1-0.5-0.40.7
Rest time, locomotor task time 10.30.31.10.2-0.30.20.50.1-1.00.20.1-0.51.1
Distance moved, locomotor task time 10.60.61.4-1.2-0.7-1.00.9-0.8-0.5-0.8-0.8-0.60.1
Vertical activity count, locomotor time 10.00.00.3-0.2-0.1-0.10.10.10.10.00.10.0-0.5
Time >=10cm from walls, locomotor time 20.20.20.70.30.50.1-0.50.30.40.40.80.2-0.4
Bouts of movement, locomotor time 20.40.41.40.1-0.7-0.10.6-0.0-0.90.10.1-1.20.9
Total resting periods, locomotor time 20.30.31.00.3-0.60.10.60.1-0.80.10.2-1.00.7
Rest time, locomotor task time 20.10.10.40.60.30.5-0.20.10.20.20.30.30.1
Distance moved, locomotor task time 20.70.81.8-1.3-0.9-1.01.0-0.8-0.9-0.8-0.8-1.00.3
Vertical activity count, locomotor time 20.40.40.8-0.9-0.6-0.80.7-0.5-0.5-0.5-0.5-0.70.2
Weight adjusted by age0.20.20.5-0.6-0.1-0.60.1-0.70.3-0.7-0.5-0.1-0.1
Seeking ratio, delayed vs. immediate footshock3.84.45.82.42.12.3-2.02.21.82.22.21.8-1.9
Locomotion in novel chamber0.50.62.3-0.30.7-0.1-0.60.11.30.20.21.1-1.5
Locomotion in novel chamber post-restriction0.81.01.70.81.30.9-1.10.91.01.00.61.1-1.1
Progressive ratio0.20.30.60.50.30.7-0.10.80.30.70.60.5-0.2
Food seeking constrained by brief footshock1.92.33.6-1.3-1.5-1.81.4-1.5-1.5-1.4-1.1-1.91.7
Seeking ratio, punishment vs. effort0.91.11.8-0.9-1.0-1.20.8-1.2-1.1-1.1-0.8-1.30.9
Run reversals in cocaine runway, females0.40.41.00.00.80.1-0.90.11.00.10.20.8-0.9
Run reversals in cocaine runway, males1.71.73.7-1.3-1.0-1.50.3-1.8-0.6-1.9-1.9-0.80.8
Latency to leave start box in cocaine runway0.20.20.6-0.5-0.4-0.30.4-0.1-0.6-0.1-0.6-0.30.8
Latency to leave start box in cocaine runway, F0.20.30.50.30.50.4-0.60.60.50.60.30.7-0.3
Latency to leave start box in cocaine runway, M1.91.83.2-1.1-1.4-1.01.6-0.9-1.8-0.9-1.2-1.51.7
Cd content in liver1.01.11.8-1.3-1.2-0.91.2-0.9-0.9-0.9-1.2-0.90.8
Co content in liver0.20.20.5-0.4-0.7-0.20.7-0.2-0.7-0.2-0.1-0.50.4
Cu content in liver4.45.36.22.22.52.1-2.52.22.32.22.12.4-2.5
Fe content in liver0.10.10.3-0.5-0.3-0.50.10.20.20.00.10.1-0.1
K content in liver0.90.91.51.20.81.1-0.90.90.80.81.20.8-0.9
Mg content in liver1.91.93.71.81.31.5-1.11.41.01.31.91.2-1.2
Mn content in liver0.30.30.7-0.7-0.2-0.60.5-0.9-0.3-0.8-0.8-0.30.3
Na content in liver3.23.44.41.81.91.7-2.11.81.71.81.61.9-1.9
Rb content in liver0.00.00.10.30.10.1-0.1-0.00.0-0.10.20.1-0.1
Se content in liver0.50.61.10.50.90.5-1.10.61.10.50.41.0-0.9
Sr content in liver0.80.71.00.81.01.0-0.90.80.70.80.30.9-1.0
Zn content in liver1.11.21.90.91.20.7-1.40.91.40.91.01.3-1.3